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Front Matter (PDF) Th eJournal of Immunology VOLUME 196, NUMBER 7 • APRIL 1, 2016 • WWW.JIMMUNOL.ORG ™ IMMUNOLOGYPROGRAM ISSUE2016 IMMUNOLOGY 2016 ™ PROGRAM PREVIEW The American Association of Immunologists AAI Annual Meeting May 13–17, 2016 | Seattle, Washington Washington State Convention Center The American Association of Immunologists Career Award Recipients for 2016 The American Association of Immunologists proudly announces the 2016 recipients of AAI awards for outstanding research and career achievements. The 2016 AAI award winners will be recognized at IMMUNOLOGY 2016™ May 13–17, Seattle, Washington. AAI Lifetime AAI Distinguished Achievement Award Service Award In recognition of a career For outstanding service to AAI of scientific achievement and and the immunology community contributions to AAI and as the AAI Secretary-Treasurer fellow immunologists for two terms, 2009–2015 Olivera J. Finn, Ph.D. Mitchell Kronenberg, Ph.D. University of Pittsburgh School of Medicine La Jolla Institute for Allergy & Immunology AAI-Steinman Award for AAI-BioLegend AAI-Thermo Fisher Human Immunology Research Herzenberg Award Meritorious Career Award For significant, For outstanding For outstanding sustained research research achievement in contributions contributions immunology to the field to the field research pertinent of immunology of immunology to human disease pathogenesis, in the area prevention, or of B cell biology therapy Lieping Chen, M.D., Ph.D. John F. Kearney, Ph.D. Kenneth M. Murphy, M.D., Ph.D. Yale School of Medicine University of Alabama, Birmingham HHMI, Washington University School of Medicine AAI-BD Biosciences AAI Excellence Investigator Award in Mentoring Award For outstanding, early-career In recognition of exemplary research contributions career contributions to a future to the field of immunology generation of scientists Ming Li, Ph.D. Richard A. Flavell, Ph.D. Memorial Sloan Kettering Cancer Center HHMI, Yale School of Medicine and Cornell University www.IMMUNOLOGY2016.org PROGRAM PREVIEW IMMUNOLOGY 2016 ™ AAI PRESIDENT’S PROGRAM AAI President’s Address FRIDAY, MAY 13, 5:00 PM Washington State Convention Center, Ballroom 6BC Dan R. Littman HHMI, New York University School of Medicine, AAI President From the thymus to the mucosa: a three-decade journey Arthur Weiss , HHMI, University of California, San Francisco Dan R. Littman Introduction AAI President’s Symposium: Host Immune Responses to Viruses MONDAY, MAY 16, 12:30 PM – 2:30 PM Washington State Convention Center, Ballroom 6BC Chair: Dan R. Littman, HHMI, New York University School of Medicine, AAI President Speakers: Adolfo Akiko Iwasaki Garcia-Sastre Adolfo Garcia-Sastre, Mount Sinai School of Medicine Regulation of innate immune pathways during RNA virus infections Akiko Iwasaki, HHMI, Yale School of Medicine Antiviral immune responses at mucosal surfaces Louis J. Picker, Oregon Health & Science University CD8+ T cell recognition of cytomegalovirus: who is in charge? E. John Wherry, University of Pennsylvania Development and reversal of T cell exhaustion Louis J. Picker E. John Wherry IMMUNOLOGY 2016™ THE AMERICAN ASSOCIATION OF IMMUNOLOGISTS AAI President’s Symposium Adolfo Garcia-Sastre is a consummate virologist and one of the leading authorities on infl uenza virus. His studies have led to an understanding of how diverse negative strand RNA viruses evade host innate immune responses and provided key insights toward developing better vaccines. His laboratory pioneered approaches to generate recombinant infl uenza viruses which led to major breakthroughs in revealing the molecular basis of infl uenza virus pathogenicity. Akiko Iwasaki studies how viruses interact with the host immune system at mucosal surfaces. She has studied immune responses to herpes simplex viruses in the genital tract and to infl uenza virus infection in the lung. Her laboratory has characterized the role of pattern recognition Dan R. Littman receptors and of autophagy in antiviral responses and AAI President host tolerance to virus-induced damage. Her research also has revealed the mechanism by which mucosal dendritic cells prime virus-specifi c T cell responses. Akiko’s recent innovative work on developing mucosal vaccines that elicit t has been a privilege to serve the immunology resident memory T cells holds great promise. Icommunity during my years as an AAI Council member and offi cer. It is a particular pleasure to organize the Louis Picker studies antiviral effector and memory T President’s Symposium for this year’s annual meeting - a cell responses in humans and non-human primates. His milestone meeting being the 100th!* I have chosen a theme group has developed approaches to elicit lasting antiviral that remains dear to my heart. While I was a postdoctoral immunity against pathogenic SIV and has studied the fellow working on cloning genes encoding T cell surface potential of CMV vectors for this purpose. They have molecules, the AIDS epidemic struck, and it quickly investigated the properties of CMV genes in priming T cell became clear that the virus attacks T helper cells. Because responses in macaques and shown that they can use CMV of my work on CD4, called T4 at that time, the mechanism vectors to generate diverse T cell responses, including CD8 of viral entry became a major focus of my new laboratory. T cells specifi c for primate lentiviral antigens presented by MHC-II and MHC-E. These advances have provided In the 20 years since the discovery of CCR5 as the major valuable insights for developing effective HIV vaccines. “co-receptor” required for HIV entry, awareness has grown of the importance of diverse innate signaling pathways Investigation of antiviral T cell responses has provided in protecting the host from pathogenic viruses, and invaluable insights into mechanisms of tumor-specifi c our interest has shifted toward elucidating the roles of immunity. John Wherry has been a key contributor in dendritic cells in HIV pathogenesis. At the same time, it this area. His early studies of CD8 T cell responses to has become increasingly clear that development of an HIV LCMV revealed the phenomenon of “T cell exhaustion” vaccine would be a monumental task requiring a much and the role of inhibitory receptors such as PD-1 in this better understanding of how both adaptive and innate process. Wherry’s ongoing studies on the molecular and immune system components interact with the virus and epigenetic underpinning of T cell exhaustion are relevant its products. Although progress in this area has been slow, for developing both antiviral and antitumor therapies. there have been very encouraging advances during the past few years, and there is renewed hope that effective * AAI canceled three successive annual meetings (1943-1945) vaccines will be developed. because of travel restrictions imposed during World War II. I have chosen to highlight some of the recent exciting work in virus-host interactions by inviting four investigators who are doing pioneering work on diverse viruses and their interactions with innate and adaptive branches of the immune system. www.IMMUNOLOGY2016.org AAI LECTURES AND AWARD PRESENTATIONS AAI DISTINGUISHED LECTURERS AAI BUSINESS MEETING & AWARDS PRESENTATIONS SATURDAY, MAY 14 SATURDAY, MAY 14, 1:00 PM - 2:30 PM 6:00 PM, BALLROOM 6BC AAI reports on the “state of the association” to its members Ulrich H. von Andrian at every AAI annual meeting. Members will hear from the Harvard Medical School Executive Director, the Secretary-Treasurer, the Editor-in- Career decisions: how T cells remember Chief of The Journal of Immunology (The JI), and the Chair of pathogens the Committee on Public Affairs on the fi nancial standing of AAI, the status of The JI, important public policy issues, and other items of interest to the membership. Selected 2016 AAI awards will also be presented during this session. AAI Distinguished Service Award Presentation SATURDAY, MAY 14, 1:00 PM SUNDAY, MAY 15 Mitchell Kronenberg, La Jolla Institute for 6:00 PM, BALLROOM 6BC Allergy & Immunology Susan K. Pierce For outstanding service to AAI and the NIAID, NIH immunology community as the AAI How B cells adapt in a changing world Secretary-Treasurer for two terms, 2009-2015 AAI annually provides more than 800 AAI meeting travel awards and grants to recognize the promise and bolster the professional development of investigators of all career stages, including underrepresented scientists and trainees. Travel award and grant presentations and acknowledgments will include: MONDAY, MAY 16 Presentations 6:00 PM, BALLROOM 6BC John J. O’Shea AAI-Thermo Fisher Trainee Achievement Awards NIAMS, NIH Chambers-eBioscience Memorial Award Cytokine signaling: genes, genomes, and Lefrançois-BioLegend Memorial Award drugs Lustgarten-eBioscience Memorial Award Pfi zer-Showell Travel Award Acknowledgments AAI Early Career Faculty Travel Grants AAI Laboratory Travel Grants FASEB MARC Poster/Platform (Oral) Presenter Travel Awards Sponsored by FASEB MARC Program under a grant from NIGMS, NIH [FASEB MARC Program: T36-GM08059-32 NCE] AAI Undergraduate Faculty Travel Grants AAI Trainee Abstract Awards AAI Trainee Poster Awards IMMUNOLOGY 2016™ THE AMERICAN ASSOCIATION OF IMMUNOLOGISTS AAI AWARD LECTURES AND PRESENTATIONS AAI Lifetime Achievement Award Presentation AAI-BioLegend Herzenberg Award Presentation and Lecture FRIDAY, MAY 13, 5:00 PM Generously supported by BioLegend Ballroom 6BC Chair: SUNDAY, MAY 15, 1:30 PM – 2:30 PM Dan R. Littman, HHMI, New York University School of Medicine, Ballroom 6E AAI President Chair: Award Recipient: Dan R. Littman, HHMI, New York University School of Medicine, Olivera J. Finn, University of Pittsburgh AAI President School of Medicine Award Recipient: John F. Kearney, University of Alabama, AAI President Dan R. Littman will introduce Birmingham the awardee and present the award prior to the B cell repertoire ontogeny infl uences allergy and start of the President’s Address. autoimmunity The AAI Lifetime Achievement Award is the highest honor bestowed by the AAI Council upon an AAI member. This award recognizes a deserving member for a career of scientifi c achievement and for AAI President Dan R. Littman, Gene Lay, Chief Executive contributions to AAI and fellow immunologists.
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