WOUND HEALING SUPPORT

DOGS+ HORSES + CATS

SKIN CREAM WITH Zinc Oxide + 9 Herbal Extracts

With different regenerative properties that are an aid to natural wound healing. Speeds up wound healing DERM-10 Unique composition Regenerates and soothes damaged skin ZINC is a cofactor for ECHINACEA PURPUREA CALENDULA OFFICINALIS many metalloenzymes induces a stimulation is one of the best wound Applicable to all types required for cell membrane of the immune healing and antiseptic repair, cell proliferation, responses mediated phytotherapeutic agents. growth and immune either by macrophages Calendula is used for of non-penetrating system function. It plays or lymphocytes5. In healing of all kinds of a major role in regulating addition, can bind with wounds, especially indicated or superficial wounds every phase of the hyaluronic acid and form for the treatment of wound healing process; a stable complex unable chronic suppurative lesions ranging from membrane to be broken down by which are extremely repair, oxidative stress, hyaluronidase. Also, difficult to cicatrize. coagulation, inflammation stimulates fibroblasts Has also important anti- and immune defense, cell growth which inflammatory and analgesic tissue re-epithelialization, participates in the wound properties and contributes angiogenesis, to fibrosis/ healing process. in easing the pain9,10,11. DERM-10 is a smooth cream containing scar formation1,2. powerful wound healing agents for a rapid recovery of all kinds of non-penetrating CENTELLA ASIATICA HAMAMELIS VIRGINIANA THUJA OCCIDENTALIS or superficial wounds. can promote wound healing restores and strenghtens can be used topically for by inhibiting inflammation, vein elasticity and healing of many kind of DERM-10 works quickly and deeply. inducing collagen synthesis, stimulates new skin infected wounds. Evidence promoting angiogenesis, micro-circulation within has shown it has antiviral, The rapid healing helps to prevent the inducing vasodilation, and the new-formed tissue. anti-inflammatory, and developments of scar tissue and allows reducing wound oxidative This property also antibacterial properties12. to regain the normal hair structure and color SKIN CREAM WITH stress. In addition, C. prevents formation of asiatica extracts have been scar tissue. Its astringent after total recovery. ZINC OXIDE + 9 HERBAL EXTRACTS shown to affect cellular and hemostatic property MELALEUCA VIRIDIFLORA Centella asiatica, Echinacea purpurea, Calendula officinalis, growth and proliferation helps to treat skin it’s used mainly for its anti- 3 DERM-10 can be applied as a preventative on Hamamelis virginiana, Melaleuca viridiflora, Thuja occidentalis, in injured tissues . inflammations and protect microbial effect without 6,7 irritating sensitive tissues13. areas where the skin is frequently at risk of injury. Lavandula angustifolia, Salvia lavandulifolia, Arnica montana against infections .

LAVANDULA ARNICA MONTANA SALVIA WOUNDS SKIN FREQUENTLY AT RISK OF INJURY ANGUSTIFOLIA can be used for sprains, LAVANDULIFOLIA accelerates wound healing dislocations, edema has been traditionally through: formation of associated with used for its antiseptic, granulation tissue by fractures, in arthralgia analgesic, sedative and collagen synthesis; tissue and rheumatic pain in anesthetic activities14. remodeling by collagen the joints. It has anti- replacement; and wound inflammatory and mild ABRASIONS ULCERS BURNS INSECT BITES ELBOWS HARNESS SADDLES contraction (shrinking)4. analgesic effect8. SUPPORT POINTS SUPPORT POINTS

Easy and Proven efficacy + hygienic synergic wound healing properties Main benefits of DERM-10

PROVEN EFFICACY CONVENIENCE APPLICATION

All components are recognised Air less dispenser bottle for 1 Clean the injured tissue and SKIN SKIN LOCAL surrounding skin before applying. ANTISEPTIC REGENERATION INFLAMMATION HEMOSTASIS ANTIOXIDANTS NUTRITION by scientific bibliography for easy and hygienic application. their properties. 2 presentations: 50 and 150 ml. If there are crusts, they must ZINC OXIDE be washed off gently, until its CENTELLA ASIATICA VERSATILITY Cream with pleasant smell, complete removal. doesn’t taint the skin or leave ECHINACEA PURPUREA 2 Apply enough to create a thin Can be applied to any type any stains on fabrics. protective layer of cream CALENDULA OFFICINALIS of superficial injury. on the surface. HAMAMELIS VIRGINIANA Apply at least twice a day COMPATIBILITY Airless dispenser MELALEUCA VIRIDIFLORA (when using a bandage, can be applied only once a day). THUJA OCCIDENTALIS Can be used on its own

LAVANDULA ANGUSTIFOLIA or along side other products.

SALVIA LAVANDULIFOLIA

ARNICA MONTANA WOUND HEALING SUPPORT

DIRECTIONS FOR USE COMPOSITION

Wound healing enhancer for skin PER 100 g Excipients: Water, Polysorbate 20, regeneration of abrasions, lacerations, Centella asiatica 2 g Polysorbate 80, Glycerol monostearate, ulcers, burns, insect bites and stings. Echinacea purpurea 1,73 g Ethyl alcohol,Liquid paraffin, Arachis Preventively on areas where the skin oil, Isopropyl myristate, Glycerol, Aerosil Calendula officinalis 1,7 g is frequently at risk of injury. 200-silica, Methylparahydroxybenzoate, Hamamelis virginiana 1,66 g Can be used single or in combination with Propylparahydroxybenzoate. other products. Melaleuca viridiflora 1,12 g Helps to prevent the development of scar Zinc oxide 0,9 g tissue and allows to regain the normal hair Thuja occidentalis 0,57 g RECOMMENDATIONS structure and colour after total recovery. Lavandula angustifolia 0,55 g For dogs, cats and horses. Do not use in cases where a possible Salvia lavandulifolia 0,35 g or known hypersensitivity to any of the Arnica montana 0,11 g components is known. APPLICATION If ingested, do not encourage vomiting, give plenty of water. Can be applied to uncovered or dressed If in contact with the eyes, rinse with wounds. plenty of water for at least 15 minutes. Crusts should be washed off gently Store in a cool and dry place. before application. Apply enough cream to create a thin protective layer on the affected surface, at least twice a day. Airless dispenser

1. PEI-HUI LIN, et al (2017) Zinc in Wound Healing Modulation. Nutrients 8. KRIPLANI P, et al (2017) Arnica montana L. - a plant of healing: review. J Pharm Pharmacol. 69(8): 925-945. 2. AGREN MS1, et al (1993) Effects on wound healing of zinc oxide in a hydrocolloid dressing. J Am Acad Dermatol. 29(2 Pt 1): 221-7. 9. FLEISCHNER AM (1985) Plant extracts: to accelerate healing and reduce inflammation. Cosmet toilet. 100: 45. 3. SOMBOONWONG J1, et al (2012) Wound healing activities of different extracts of Centella asiatica in incision and burn wound models: an experimental animal study. 10. PEYROUX J, et al (1981) Propriétés anti-oedémateuses et anti hyperhémiantes BMC Complement Altern Med.12: 103. du Calendula officinalis. Plant. Méd. Phytotherap. 15: 201-216.

4. HIROKO-MIYUKI MORI, et al (2016) Wound healing potential of lavender oil by 11. KIOUCEK-POPOVA E, et al (1982) Influence of the physiological regeneration acceleration of granulation and wound contraction through induction of TGF- and epithelization using fractions isolated from Calendula officinalis. Acta Physiol. in a rat model. BMC Complement Altern Med. 2016; 16: 144. Pharmacol. Bulg. 8: 63-67.

5. LUETTIG B, et al (1989) Macrophage activation by the polysaccharide 12. ŞULEA D, et al (2009) Collagen-thuja tincture biomaterials for wound treatment. arabinogalactan isolated from the plant cell cultures of Echinacea purpurea. Revue Roumaine de Chimie. 54: 11-12, 1097-1101. J. Nat Cancer Inst. 81(9): 669-75. 13. RAMANOELINA AR, et al (1987) Antibacterial action of essential oils extracted 6. NEWAL C., et al (1996) Herbal medicines: a guide for health-care professionals. from Madagascar plants. Arch Inst Pasteur Madagascar. 53(1): 217-26. Pharmaceutical Press London. 14. PORRES-MARTINEZ M, et al (2013) Pharmacological activity of Salvia lavandulifolia 7. Van Hellemont J (1986) Compendium de Phytotherapie. Eds APB Brussels. and chemical components of its essential oil. A Review. Lazaroa 34(1): 237-254. DERM1020EN3

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