Producers of Machines for Electrospinning Usage of Electrospun Materials

Výrobci zařízení pro elektrostatické zvlákňování Použití elektrostaticky zvlákněných nanovláken

PRODUCERS OF MACHINES FOR ELECTROSPINNING USAGE OF ELECTROSPUN MATERIALS

5. přednáška MACHINES FOR ELECTROSPINNING ON MARKET Elmarco (Czech Republic) NS, NanospiderTM Three diferent spinning electrodes: Elmarco

Laboratory devices – spinning from the wire http://www.youtube.com/watch?feature=player_embedded&v=R01BLyqrWlQ http://www.youtube.com/watch?v=IRc120Ceq9o&feature=player_embedded http://www.youtube.com/watch?feature=player_embedded&v=R01BLyqrWlQ Contipro (Czech Republic) 4SPIN® CONTIPRO GROUP CONTIPRO GROUP CONTIPRO GROUP Spinning electrodes

Collectors CONTIPRO GROUP

Electroblowing Technika kombinující elektrostatické zvlákňování s prouděním vzduchu kolem zvlákňovací elektrody

Umožňuje: - úpravu klimatických podmínek kolem zvlákňovací elektrody -Snížení viskozity (při zvýšené teplotě proudícího vzduchu) -Zvýšení rychlosti odpařování rozpouštědla -Ovlivnění morfologie nanovláken -Atd. CONTIPRO GROUP

4SPIN video http://www.youtube.com/watch?feature=player_embedded&v=40W- WABZJaY SPUR (Czech Republic) SPIN Line http://www.spur-nanotechnologies.cz/video/Spur1.swf MECC (Japonsko) Nanon Zvlákňovací elektrody MECC

Jehlová elektroda Jehlová elektroda - klipová - Pro malá množství roztoku

Jehlová elektroda - koaxiální KOLEKTORY MECC

Deskový Diskový

Bubnový - Jádrovitý – pro výrobu tubulárních válcovitý nanovlákenných útvarů Prezentační video MECC http://www.youtube.com/watch?v=KBvHJs3A9k4&feature=player_ embedded FNM (Irán) Nanorassam ® (průmyslová výroba) Electroris ® (laboratorní výroba)

Melt electrospinning Electrospunra (Čína) Laboratorní – roztok Laboratorní – tavenina Ruční zařízení

TOPTEC (South Korea) Electrospinning from jets

http://cdn.intechopen.com/pdfs-wm/23289.pdf www.toptec.co.kr NanoStatics (Ohio, USA) Electrospinning from jets

http://cdn.intechopen.com/pdfs-wm/23289.pdf

NanoStatics Corporation has developed advancements in electrohydrodynamic spinning (EHS) technology for the production of high through-put nanofibers. - See more at: http://www.bioohio.com/directory/nanostatics- corporation/#sthash.tMkb3O7p.dpuf Electrospun materials Utilization - Applications

Eva Košťáková KNT, FT, TUL http://www.elmarco.com/nano/industry- applications 2005 Ramakrishna S., An introduction to Electrospinning and Nanofibers Statistics on the literature published on the advanced applications of electrospun fibers in the period 2001–2012 (search made through Scifinder: Keywords Electrospinning + area of application).

http://www.sciencedirect.com/science/article/pii/S1381514812002416 FILTRATION

Air

WOUND DRESSING

Fabrics of nanofibers can be used to cover wounds, where they provide oxygen to penetrate, drainage of exudate while preventing bacteria from entering the wound. At the same time they can be connected some supporting materials, such as antimicrobial and hemostatic drug or medicament for accelerating the healing process; Sound absorbtion

Basic fibrous material with the nanofibrous layers of different area densities (colored curves) vs. Basic material without the nanofibers (black curve)

0,8

0,6  0,4

0,2

0 100 1000 10000 f [Hz]

basic material nano-1 g.m-2 nano-0,5 g.m-2 nano-0,1 g.m-2 http://www.protext.cz/english/zprava.php?id=76 74 Agriculture The dosage of fertilizers Membranes for clothing industry

A nanofiber membrane made by NANOPROTEX can boast of extremely high steam permeability, which is given by the unique nanofiber structure, and a nanofiber diameter which is only 150 nm (those are the finest fibres ever used in the textile industry). The research team found additional inspiration for nanofiber membrane development in human skin, which enables the so-called insensible perspiration. Thanks to this structure and nanofiber diameter the NANOPROTEX nanomembranes have more pores per given area compared to microporous membranes. This results in the steam permeability of the 2-layer laminate (face fabric + nanofiber membrane) Ret below 1.5 Pa.m2.W-1. The steam permeability of the nanofiber membrane itself is Ret 0.0 Pa.m2.W-1. Membranes for clothing industry Membranes for clothing industry

Permeability

Breathability (vapor permeability) hydrostatic pressure (the water column)

Wind resistance Drug delivery systems Tissue Engineering Tissue Engineering The temporary structure built around a building for the "convenience" of work of employees

What is the scaffold?

The construction for the cultivation of cells and tissues. Tissue Engineering Tissue Engineering

PES nanofibers and stem cells Textile scaffold Nonwoven material In vitro testing

Electrospun material - PCL PCL electrospun nanofibers (3D structure + hydroxyapatite) with fibroblasts after 10 days cultivation in-vitro Aligned and non-uniform nanofibrous structure with cells

a b c d

Zhong, S., Teo, W., E., Zhu, X., Beuerman, R., W., Ramakrishna, S., Yung, L., Y., L.: An aligned nanofibrous collagen scaffold by electrospinning and its effects on in vitro fibroblast culture, Journal of Biomedical Materials Research Part A, pg.456-463, 2006, http://sites.google.com/site/biophysicsgroupucl/Home/recent-publications-1 E. Košťáková, KNT, FT, TUL Nejpoužívanější materiály pro výrobu elektrostaticky zvlákněných materiálů užívaných v tkáňovém inženýrství:

PLA – polylactid acid

PGA – polyglycolic acid

PLGA – copolymer of lactid and glycolic acid

PCL – poly--caprolactone

Chitosan Gelatine Collagen Etc. Nanofibers – Production, Properties and Functional Applications 290 Fig. 3. The cross-sectional images of a double-layered small diameter PU vascular graft before (a) and after (b) cell culturing (Blue, nuclei; green, F-action; red,scaffold) (Soletti et al., 2010). A scaffold production

In vitro – testing

Implantation – in vivo testing Textile scaffold In vivo testing Normal and new cartilage

80x Textile scaffold In vivo testing

Mag. 40x

New cartilage Old cartilage

Chondrocytes has to penetrated to the scaffold, created structures typical for cartilage (collage type II), has to treat osteochondral defects.. http://www.spellmanhv.com/en/About/Typical-Applications/Electrospinning.aspx http://www.electrospunra.com/sub/ped.html#page_1/ The electrospinning is capable to prepare novel materials with enhanced electrochemical properties of the primary functional components (electrolyte, anode and cathode) of lithium ion batteries.

Principle of LiFePO4 charge/discharge process in lithium Schematic representation of charging and http://www.sciencedirect.com/science/article/pii/S13815148ion battery. discharging processes of lithium ion battery 12002416# with PE based on ESM. HOMEWORK to 11.12.2013

Find in a literature (articles, monographs, www etc.) any interesting application of electrospun nanofibers. Write about it one A4 page (text can include also figures).

You can bring it printed or send me it by email. Kompozitní a nanokompozitní materiály pro tkáňové inženýrství PĚNY

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