THE LIFE AND TIMES OF DR. WILLIAM HARVEY* By SIR WILMOT HERRINGHAM, K.C.M.G., C.B., M.D., F.R.C.P. HAMPSTEAD, ENGLAND
Part ii * difficulty made it harder for English- in. Harv ey fr om 1600 to 1628 men to study in Italy, and the Dutch On leaving Cambridge Harvey went schools rose to the first place. to Padua to complete his medical Harvey’s master in anatomy, of studies. He there appears as D. whom he always speaks in terms of Gulielmus Arveius, Anglus, first in the highest veneration, was Fabricius the list of the English students in the ‘da Aquapendente. Galileo was lectur- Universitas Juristarum for 1600. There ing to immense audiences when Harvey was also at Padua a Universitas was there, but Fabricius’ theater, Artistarum (Universitas in medieval which is still in existence, is a small Latin was used of any club association area surrounded by a steep series of or corporation), including the faculties steps on which the students stood and of divinity, medicine and philosophy, looked down upon the dissection be- to which Harvey would more properly neath, much as fifty years ago students have belonged, but the Jurists’ Uni- looked down on operations in some versitas was the more fashionable of surgical theaters at our London schools. the two. The entry is repeated in 1601, Harvey’s diploma, which is pre- and there is also a record on August 1, served at the College of Physicians, 1600, 1601, and 1602 that Harvey was is couched in very florid language, and elected Member of Council (Con- has sometimes been quoted as a proof ciliarius) of the English nation in of his early excellence, but, judging the same association, so that though from other diplomas, it was the he took his degree April 25, 1602, he language ordinarily used. It bears at appears to have remained at Padua at the top of the first page “an oval any rate until August. shield gules a dexter sleeved arm and Padua had been during the 16th hand issuant from the sinister side, century, the chief center of anatom- sustaining pale-wise a candle lighted ical research and teaching. Vesalius, argent with rays or issuant from the Eustachius, Columbus, Falloppius and flame and entwined by two serpents of Fabricius, who by dissection of the the second.”12 This shield is painted human body, which was unknown to twice in the lower cloister at Padua, Galen, had laid afresh the foundation and is reproduced also in the portrait of human anatomy, were all professors of Harvey at Ditchingham, where it is at Padua, and English physicians accompanied by the motto Piu arde beginning with Caius, who lived in the piu splende, “The more it burns, the same house with Vesalius, and Linacre, more it shines.” A copy also hangs in resorted thither to learn medicine, the library of the College of Physicians. and commonly took the Paduan m.d . In 1602, Harvey returned to Eng- In the 17th century the religious land, incorporated m.d . at Cambridge, * Part i of this article appeared in the March, 1932 issue of the Annals of Medi cal Hist ory , vol. iv, No. 2, p. 109. and settled in St. Martin’s, Ludgate. Elizabeth and King James, and died To his early years belongs the in 1605.14 following record; perhaps to 1604.13 On June 5, 1607, Harvey was elected a Fellow of the college, and on Febru- ary 25, 1609, he applied for the post To the Right Honourable Sir Thomas Lowe Knight. of Physician in Reversion, correspond- ing to what is now Assistant Phy- Whereas it hath pleased His Majesty to direct his privy seal to William Harvey sician, to St. Bartholomew’s Hospital, doctor of physic for to borrow of him six bringing letters of recommendation pounds and thirteen shillings and four- from the King, obtained, perhaps, pence we whose names are underwritten through his brother John, and testi- do certify unto you that the said Doctor monials from Dr. Adkyns, President Harvey is a young man whose father is of the College of Physicians, and other yet living and that being to begin the Fellows. The Court of Governors world and to live by his profession his “granted at the contemplation of means and abilities are such as in our His Majesty’s letters that the said judgment he is unfit to lend. Mr. Harvey shall have the said office Robert Shawe Joseph Fenton next after the decease or other depar- [Signature illegible] Richard Coop ture of Mr. Doctor Wilkenson who Ric. Mapes. Edw. Grayne now holdeth the same,” provided he Adam [illegible] Henry Warden. be not then in any other employment [These persons who are unknown were that may hinder him in performing probably neighbors.] the duties of the office.15 Dr. Wilkenson died that summer, He was admitted a Candidate, which and the house committee, on August corresponds to the membership of the 28, provisionally appointed Harvey to College of Physicians of the present execute his office until the Court time, on August 7, 1604. For some should meet. On October 14, the reason his examination was inter- Court made the appointment. All rupted. He presented himself for the officers of the Hospital to the present first time on May 4, 1603, ubi examina- day receive a charge on appointment, tus ad omnia satis apte respondit. and Harvey’s Charge is preserved in Nihilo minus in alium tempus dilatus the Journals and printed at length est cum conniventia ad Praxin, that is, by Sir D’Arcy Power.16 he was allowed to practice though A curious episode occurred a week the examination was left unfinished. later, when John Harvey prosecuted He was examined a second time Marten Llewellyn the Steward of the on April 2, 1604, and on August Hospital for a debt of £52.10.0, long 7, was again examined and elected overdue to William Harvey. The (et eligitur). He was formally admitted steward was ordered by the Lord a sworn “Secundum formam Statuto- Mayor and Aidermen to pay the rum pro Candidatis” on Oct. 5, follow- whole of his yearly stipend of £10 to ing. On November 24 of that year Dr. Harvey till the debt should be he was married at St. Sepulchre’s, at fully paid.17 the corner of Giltspur Street, to In 1613 Harvey was appointed Elizabeth, daughter of Dr. Lancelot Censor of the College of Physicians. Browne, who was Physician to Queen It was an office of great responsibility then, as it is now. He was appointed James 1 to William Harvey Censor again in 1625, and in 1629. Royal Letters, Warrants. On August 4,1615, he was appointed Trustye and welbeloved, wee greet you Lumleian Lecturer to the College. well. Whereas we were graciously pleased The Lumleian was a lectureship on heretofore to promise you the next place surgery and anatomy founded by which should fall voyde by death, resig- Lord Lumley at the instance of Dr. nation or otherwise of Dr. Attkins, Dr. Mayerne, Dr. Chambers or Dr. Lister, Caldwell in 1581. Lord Lumley was a our foure physitians in ordinarie which Knight of the Bath and highly re- wee intend shall be certainly performed, spected for his character. He died in we have though fitt neverthelesse out of 1609 without issue. Dr. Caldwell was our speciall favor unto you, in respect a well-known and respected physician both of your ability in your profession who had the unusual honor of being and allso of your long being our servant appointed Censor the very day that extraordinary, to lett you knowe that in he was elected Fellow, December 22, the meantyme your attendance upon our 1559. He was President in 1570 and Person shall be as gratefull and with as died in 1584. A regular course extend- much freedome to waite as our other ing over six years was laid down for physitions doe. Given under our signet at the lectures, which were to consist of our pallace of Westmr. the third day of ffebruary in the twentieth year of our readings from received authors on Raigne of Great Brittain, ffrance and surgery with comments, partly in Ireland. Latin and partly in English, together with dissections in the winter. Harvey, In March, 1625, he and his brother John however, gave his first anatomical were admitted Members of Gray’s lectures, on the viscera, on April 16, Inn and in that month he attended 17 and 18, 1616. His notes, half King James in his last illness. Latin and half English, written in his When, in 1626, the House of Com- execrable handwriting, were found, mons accused Buckingham of High after they had long been lost, in the Treason before the House of Lords, British Museum, in 1876. They were the thirteenth Article of the Accusa- photographed, deciphered and printed tion stated that the Duke had been by the College. guilty of “transcendent presumption” On May 7, 1618, the College pub- in administering to the King a plaster lished the “Pharmacopoeia Londinen- and a posset, which the physicians sis,” in which Harvey, who had been a did not advise, and the ingredients member of the committee which dealt of which were unknown. Harvey had with it, is described as Medicus been examined by a Committee of Regius juratus. This is the first intima- the House before they drew up this tion of his appointment as Physician charge. The popular belief was that to the King. Buckingham, being out of favor with In February, 1620, he was appointed the old King and in intimate friend- with Mayerne and Clement on a ship with Charles, had poisoned the Committee to watch the proceedings father to place the son on the throne. of the Surgeons. The following letter Traces of this opinion may be found or warrant, mentioned by Lawrence18 in the speeches of the *accusers. But in his Life, was written to Harvey by * It is repeated long afterwards by Milton James 1 in 1623: in the “Defensio,” Ch. v. “Nero” inquis Harvey’s evidence shows that the which his fame commonly rests. “Ex- medicaments used had been found of ercitatio Anatomica de Motu Cordis benefit both by Warwick and Buck- et Sanguinis.” ingham, that the King, who “took Harvey’s whole life was dominated divers things whether they would [or] by two remarkable books, the “De not, undervaluing physicians,” desired Motu” which occupied him until he to use them, and that Harvey, though was fifty, and the “De Generatione” not advising the plaster because he which was published when he was did not know its ingredients, it being seventy-three. This seems a fitting “a secret of a man of Essex” [Reming- occasion to review the work of the ton of Dunmow who attended War- first part of his life, and in order to wick], “gave way to it, thinking it understand it we must consider the easy and could do no harm,” which it state of knowledge before his time. evidently did not. The drugs in the The first physiological question posset apparently were known and which presented itself to the ancients the King drank it once or twice and was: Why does the body remain warm commended it.19 during life and become cold after All historians have agreed in believ- death? We moderns answer it by ing Buckingham innocent, but there saying that through all the minute can be no doubt about his “transcend- and intricate changes which the assim- ent presumption.” ilation of food involves, one great In 1626 Harvey was offered an principle is maintained. The body official residence in the precincts of takes in oxygen, and a vast variety of St. Bartholomew’s where many nota- preparations of carbon, converts them ble people lived, but refused it,20 and into carbon dioxide, which is dis- received instead an increase of salary charged through the lungs, and in from £25 to £33.6.8. the process of conversion produces In 1627 he served on a committee heat as does every machine which appointed by the College at the re- burns coal or any other form of quest of the Privy Council, to report carbon. This action takes place only on some alum works in St. Botofph’s, during life, but what life is we know Aidgate, which the committee con- no more than the ancients. We our- demned as a nuisance.21 selves have only reached this explana- By Gwynne’s death in November, tion since the discovery of oxygen by 1627, a vacancy was made in the Lavoisier, who perished in the French Electi. The position was offered to Revolution, but the ancients guessed Mayerne, but as he excused himself on that something of the kind took place, account of his constant employment though their notions were dominated at Court, Harvey was elected. by the facts of the kitchen rather than He was elected Treasurer of the by those of the laboratory. They College in 1628, and in that year he drew their analogies most often from published at Frankfurt the book on a boiling sauce-pan. It is not until the 16th century that Caesalpinus uses similes from chemistry. They “matrem suam ferro necavit”; Carolus et patrem et regem veneno. That and many always connected the “natural” heat other passages are a lasting disgrace to (calor innatus, deppaala tp.(pvros) with the Milton. blood, and ascribed it to some kind of “concoction” or “fermentation,” to the portal system of veins. He for their similes recall now one and thought that it carried the products now the other, which took place in of the “first concoction” (roughly the veins and especially in the heart. the same as “digestion”) to the liver, The latter was considered the hottest and then after a “second concoction” place in the body. in the liver, returned the blood, now The second problem was respira- provided with “natural” spirit and tion. What function had the lungs? suitable for nourishment, to the same Aristotle thought that their only parts. He thus gave the portal veins purpose was to reduce by the proxim- a double function, first collective and ity of the cold air inspired, the exces- then distributive, in which the blood sive heat generated in the heart. Galen ran in opposite directions. The in- made an advance on this. He thought ferior vena cava distributed the same that the blood generated waste prod- blood from the liver downwards to ucts (Juligines, rd \tyvva)8es, like the the other parts of the body below smoke from a lamp) which escaped the diaphragm, while the vena cava through the lungs and the skin, and superior, which was thought to be that it also received from the inspired continuous with it, carried it to the air something which in the heart upper parts. changed it from purple to scarlet, But a small part of the “natural” and turned what he called the “nat- or “nutritive” blood went by the ural” Spirit (Trvev/j-a William Petty was sitting under a hedge with the who travelled for him in Italy, two young princes reading a book, Greece and the Levant. The Arundel when a cannon-ball came so near them marbles were given to Oxford by his that they had to shift their quarters. descendants. He had known Harvey Harvey told him of the condition in since 1616 and he now made him a which Adrian Scrope was found next member of his suite. Harvey accom- day, so that he must have seen some- panied him to the Emperor’s Court, thing of the wounded. but after taking part in one or two In 1643 Harvey, for the last time, hunting parties, and a great dinner, drew his salary as Physician to the and after admiring the Queen of Hun- Hospital, and in that year Parlia- gary’s babies, left him, and proceeded ment, which claimed a great deal of to Italy. His adventures there will authority that did not belong to it, be described later. He rejoined the ordered the Hospital to dismiss him, Earl at Ratisbon in November, re- and appoint Dr. Micklethwayte. Par- turned with him to England at the * See Dr. William Harvey and Aberdeen by end of the year, and was present at a W. C. Souter (Aberdeen University Review meeting of the College on February Nov. 1931) who gives a conjectural explana- 13, 1637. tion of Harvey’s visit. liament sent a similar order to St. There is an additional note by Rich. Thomas’ Hospital to dismiss Mullins, Cave that the Army is about to march their surgeon and appoint Cleere. to Plymouth. The letter was therefore St. Thomas’ replied that they were probably written early in 1645 w^en accustomed to appoint their own Grenvile besieged Plymouth. officers. St. Bartholomew’s answer is Harvey was with the King at Ox- not recorded, but they did not appoint ford, and when, in January, 1645, Micklethwayte till 1648. The follow- Lennox and Southampton went to ing letter23 addressed to Prince Rupert Uxbridge to treat with the Parlia- refers to Harvey’s attendance on mentary Commissioners, Harvey went Prince Maurice during the Campaign. in the suite of the former, and his It is undated. friend, Edmund Smith, in that of the May it please your Highness. latter (Journal House of Lords). The This last night arrived here at Milton University conferred on him the degree Dr. Harvey and Dr. Smyth and this of M.D. morning they with the two other doctors Then followed the picturesque epi- having seen and spoken with His High- sode of his appointment as Warden of ness your brother intreated me to write Merton. Nathaniel Brent, a lawyer, as followeth. and vicar-general of the Province of That his sickness is the ordinary raging Canterbury, in which position he had fever of the army, a slowe fever with carried out Laud’s policy, had been great dejection of strength and since elected Warden in 1622. But on the Friday he hath talked idly and slept not outbreak of the Civil War he had but very unquietly yet the last night he joined the Parliamentary party and began to sleep of himself and took his rest so quietly that this morning when had left Oxford. In January, 1645, Dr. Harvey came to him he knew him the King pronounced his deposition and welcomed Dr. Smyth respectively as a three years’ absentee and a and upon Dr. Harvey’s expression of rebel, and directed the seven senior His Majesty’s sorrow and great care of Fellows to present three names for him he shewed an humble thankful sense the King’s choice. Following, no doubt, thereof. Dr. Harvey asking His Highness indications of the royal wishes, five of how he did he answered that he was very the seven placed Harvey first on their weak and he seemed to be very glad to lists, and he was appointed by the hear from Your Highness as was delivered King on January 27. His speech on by Dr. Harvey. Now the doctors having his reception by the College is not in conferred and computed the time have his happiest vein. He said that perhaps good hopes of his recovery yet by reason that the disease is very dangerous and his predecessors had coveted the office fraudulent they dare not yet give credit that they might enrich themselves to this alteration. And concluding the (and this charge was definitely brought disease to be venomous they do resolve against Brent), but his own hopes to give very little physic, only a regular were that he might rather enrich and diet and cordial antidotes. The doctors profit the College than himself. He present their most humble service to your ended by urging good fellowship upon Highness and subscribe themselves the Fellows. Will Harvey There was an abortive siege of Robert Vilvain Oxford by Fairfax in 1645. Naseby Edmund Smith was fought on June 14, and on April Thos King. 27, 1646, the King fled in disguise. (Journal House of Lords) in which On May 11, Fairfax summoned the Sir Edward Walker asked that either town," which on June 24 surrendered Harvey or Wetherborn,* Physicians on honorable terms. to the King, and Humfrey Painter There is I am told no record at his Surgeon might be sent to him at Merton of Harvey’s year of office. We Newport. But the request does not know however that he was accustomed seem to have been granted. Herbert to go to the rooms of George Bathurst, a says that Charles was never out of Fellow of Trinity (not Ralph Bathurst health all the last two years and a afterwards President, and f .r .s .), half of his life. He was beheaded on where the two made many observations January 30, 1649. on the incubation of eggs and the devel- Harvey, meanwhile, was living, as opment of the chick. These no doubt Ent tells us, near London, probably formed the substance of a good deal of sometimes at Roehampton with Eliab, the “De Generatione.” and sometimes at Combe with Daniel, f The Queen had been living in Mer- In 1650 he was given a pass to go to ton during the early years of Harvey’s London to see his old patient, Lady residence in Oxford, but had left in Thynne, who was on her deathbed, 1644, before Harvey became warden, and she had to guarantee that he to go to Exeter, where Mayerne and would do nothing to the prejudice Lister attended her, and where she of the Commonwealth. Harvey was was confined of Princess Elizabeth. not of the make of a conspirator, With the capture of Oxford Harvey’s but the Government were just then wardenship ended. Brent resumed exceedingly frightened by the Prince’s office, but was shortly replaced by dealings with the Scotch, and in Goddard, a well known Fellow of the February, 1650, had passed an Act College of Physicians, and one of the ordering all suspected persons, Papists, Physicians attached to Cromwell. soldiers of fortune and delinquents, Meanwhile the King had taken to leave London by March 20. It refuge with the Scotch Army, and was just at this time that Lady had by them been taken as a virtual Thynne lay dying. In this year prisoner to Newcastle. In November, occurred the interview with Ent which 1646, a pass was issued to “Dr. resulted in the publication of the Harvey, the King’s Physician,” to “De Generatione.” go to Newcastle to attend him (Jour- Harvey was, of course, reckoned as nal, House of Lords), and this was the a delinquent, in spite of his having last time that Harvey was in attend- acted under the sanction of Parlia- ance on, or saw the King. We know all ment, and Lloyd24 states that he was the details of Charles’ life after this, fined £2000 on this ground. from Herbert’s “Memoirs.” Neither It is uncertain when he obtained Harvey nor any other physician is permission to live in London again. mentioned as belonging to his scanty He had no home of his own, but when household. When Pembroke fell ill at Holmby House, John Bathurst, Crom- * Wetherborn was a Scotchman and was in the carriage with Bacon when Bacon caught well’s doctor, came down to look after the chill which caused his death. him. On September 7, 1648, a letter f Eliab and Daniel were brothers of was read to the House of Lords William. in town lived at the great mansion, At the next election, Michaelmas, Cokayne House in Broad Street, which 1654, the College elected Harvey Eliab bought in 1654. Howell, how- President. He was absent, and when ever, addressed a letter to him, prob- his election was conveyed to him by ably before this date, at Laurence Alston and Harney, declined the honor Pountney Hill where the Harveys had in very courteous terms, alleging his their house of business. But he also old age and ill health, and begged them spent his time partly at Roehampton to re-elect Dr. Prujean, which they and partly with Daniel’s widow at did. Combe or Lambeth, for he left house Harvey, however, consented to take linen of his own there as well as in office as Conciliarius, and was reap- London. pointed up to his death. A year later began that great In 1656 he resigned his Lumleian benefaction by which the College Lectureship, which he had held for hitherto somewhat unmindful of its forty years, and at the same time greatest Fellow, was driven at last, made over to the College lands in the though somewhat tardily, to recognize parish of Burmarsh in Kent, then his merits. valued at £56 per annum, which he On July 4, 1651, at an Extraordinary had inherited from his father. He Comitia: charged the revenue with an hono- “Postremo Dns Praeses a schedule, rarium to be paid for a yearly Oration (written scheluda) legit in haec verba, to commemorate College benefactors, quae avroXk&t hie inseri jussit.” and to inculcate the necessity of The President evidently read from experiment, with provision for an a sheet of paper without adding the Annual Feast, and with a salary for signature, or letting Harney, then the keeper of the Museum and Library. Register, see it. What he read was as The Harveian Oration and the Har- follows: veian Dinner are still held, and the Librarian is still the Harveian Libra- If I can procure one that will build us a rian, but though the College still owns Library and a Repository for Simples and the land, the funds have now to be Rarities, such a one as shall be suitable supplied chiefly from other sources, and honourable to the College, will you assent to have it done or no, and give me and of the Library which the College leave and such others as I shall desire, possessed only 140 volumes were saved to be the designers and overlookers of the at the Great Fire. All the rest were work both for conveniency and ornament? burned. Harvey died of cerebral hemorrhage, The offer was unanimously accepted. at Roehampton, in the eightieth year Harvey paid for the Museum, and of his age, on June 3, 1657. His body gave a large donation of books not was carried first to the Broad Street only on medicine, but also on geome- house, and thence was transported on try, astronomy, music, optics, natural June 26 to the family vault at history and travels. It was formally Hempstead Church, Essex, being es- opened on February 2, 1654, when corted out of the City by a large Harvey gave the President all the body of the Fellows of the College. title deeds and other papers connected The vault now contains about fifty with the property. of the Harvey family, each body wrapped in lead, usually without any seen to occur day by day in the hen’s wooden coffin. Harvey himself was egg, when watched through a lens in a thus buried, but in 1883, the lead basin of silver (by which the light wrapping having cracked, and the was reflected and made to illuminate conditions become unseemly, the re- the preparation). mains were ceremoniously removed to The changes are recorded daily for a marble sarcophagus erected by the the first week, and at longer intervals College of Physicians in the Chapel up to the hatch, and with these above. observations, as with the former, are The “De Generatione Animalium” mingled copious notes of animal life, contains the work of Harvey’s later always interesting, and sometimes years. He contemplated writing a delightful for the quaintness of the larger work of the same kind including English version. insects, and refers to it more than once. But he had lost all his notes on And if you listen close for some days before exclusion [hatching] you may insects when the mob sacked his perceive the chickens kick, make a noise, house in 1643, and the design, in com- and cry after their manner, which kind mon with others, was never carried out. of commotions when the sitting henne The “De Generatione” does not, discovereth in her nest, she removeth the like the “De Motu,” lead to any egges and rowleth them to and fro (as conclusion of a practical kind, and carefull mothers do their disquiet and for that reason has never excited the peevish infants in the cradle) till the interest of the earlier work, but to chickens being accomodated with con- my thinking it is the more interesting venient posture, lye hushed and still. . . of the two. It is a mine of information, The yolk is now concluded in the and it embodies a view of develop- Abdomen between the Guts; and that ment which was then completely new, not onely while the chicken remaines in the eggs, but also when he is excluded, but is that now generally held. when he walkes abroad with his Mother The book opens with a preface to seek his provision . . . urging the importance of personal observation, against which no author- Throughout, Harvey has professed ity, not even the writer’s own, should that Aristotle is his leader and Fabri- be weighed. cius his “ Praemonstrator,” and though He then selects the common fowl he occasionally corrects Aristotle he and its egg as the example by which more often corrects the criticisms he means to illustrate the stages of passed upon Aristotle by Fabricius. generation. The first thirteen chapters After he has traced the chick to its are taken up with a careful anatomical hatching he turns to the metaphysical description of the external and in- problems which arise out of it. He ternal parts of the fowl, interspersed discusses the different senses in which with continual observations on the one thing can be considered the cause natural habits of all kinds of creatures, of another, and debates whether the mammals, birds, fishes and insects, cock or hen or both can be called the and on the various ways in which they efficient or material cause of the egg, propagate their species. or the egg of the chick. At Chapter xiv begins an accurate Here we begin to understand why record of the changes which can be Bacon had such an aversion to Aris- totle. Such questions as these have that the conception of the egg in the lost all interest to us, and Bacon was ovary of the hen might literally be sufficiently modern in his outlook to paralleled by the conception of the see that how a thing happened was of elSos or mental image in the brain of much more importance, at any rate the painter. in matters concerning life, than why In the “De Motu,” when he came it happened. up against a fact that was beyond his Harvey, who is a genuine disciple of powers, such as the communication Aristotle plunges into metaphysics between the minute arteries and veins, with all his master’s fervor. He is, he made a guess which though not however, driven at last to confess quite accurate produced a workable that the father and mother are nothing theory. Here, however, he refuses to more than instruments, and that the accept the guess that had seemed efficient cause of life, or the soul, or reasonable to others. The result of the individual, whichever way it is this error has been that the “De considered, can only be referred to Generatione” has been decried, and God Himself. that nearly all opinion has ascribed Of secondary causes the soul or Harvey’s merit to the “De Motu.” principle of life resides not in the But this is a very erroneous view. heart but in the blood. In the first place the observations From Chapter lxii i to Chapter upon the development of the chick lxxii he describes the conditions in in the egg are the first reliable state- the vivipara, represented chiefly by ment of the facts. Harvey saw the man and the deer, in the same order small white spot or cicatricula, real- and method as he had those of the ized that it was the starting point of ovipara, and these descriptions again the chick, and traced its gradual are made extremely interesting not development in words which are true only by the accurate accounts which to this day. No one had done that he gives of the habits of deer and before, and Fabricius had made state- other animals, but also by a wealth of ments that were entirely erroneous. pathological details drawn from his Secondly, and this is an even greater experience as a medical practitioner. title to fame, Harvey was the first Finally there are some sections on person to formulate the theory which obstetrical practice which are full of we now hold, that development is a sound observation and advice. process of gradual differentiation from It must be allowed that all Harvey’s an originally homogeneous mass, with- speculations are vitiated by a funda- out any addition from the outside. mental mistake. Aristotle and all This was the hypothesis advocated ordinary physicians believed that both in what Huxley calls “that remarkable male and female parent made some work which would give Harvey a claim material contribution to the embryo. to rank among the founders of biologi- But Fabricius denied it and so did cal science even had he not been the Harvey. He could not see any material discoverer of the circulation of the left by the cock in the hen’s ovary, blood.”25 Harvey called the process and therefore he refused to allow that Epigenesis. there was any. The opinions that Harvey wished to He was driven to such straits by disprove were those held by the his scepticism that he even suggested ancients that growth took place by the accretion of outside bodies, whether showing that from the very first the elements or atoms. Secondly, he wished ovum contained the perfect being on to distinguish epigenesis from another a minute scale, and that this doctrine kind of generation which he called obtained then the name of the theory metamorphosis, and exemplified by of development or evolution. Though the birth of insects, which either with Wolff denied it in 1759, his work or without the pupal stage, are as he passed unheeded, and it was not until thought produced with their parts the 19th century began that Harvey’s ready made instead of gradually grow- doctrine was reestablished. We now be- ing out of a homogeneous jelly. lieve what he taught, though the the- It is a curious thing that the whole ory has taken the very names which of the 18th century was devoted to his opponents used for their own. disproving Harvey’s theory, and to (To Be Continued)