SIAPEC-IAP 2015 Congresso Annuale Il Team Roche Ti Aspetta Allo Stand! Di Anatomia Patologica 02Vol

Total Page:16

File Type:pdf, Size:1020Kb

SIAPEC-IAP 2015 Congresso Annuale Il Team Roche Ti Aspetta Allo Stand! Di Anatomia Patologica 02Vol ISSN 0031-2983 Cited in Index Medicus/MEDLINE, BIOSIS Previews, SCOPUS Guardare alla sicurezza del paziente da un nuovo punto di vista... Journal of the Italian Society of Anatomic Pathology and Diagnostic Cytopathology, Italian Division of the International Academy of Pathology Società Italiana di Anatomia Patologica e Citopatologia diagnostica Divisione Italiana della International Academy of Pathology Congresso SIAPEC-IAP 2015 Congresso Annuale Il team Roche ti aspetta allo stand! di Anatomia Patologica 02Vol. 107 June 2015 SIAPEC-IAP 2015 Innovazione e sostenibilità al servizio del malato Centro Congressi MiCo Milano 23-25 Settembre 2015 art. 1, comma DCB PISA Società Italiana di Anatomia Patologica e Citopatologia Diagnostica, Periodico trimestrale – POSTE ITALIANE SPA - Spedizione in Abbonamento Postale D.L. 353/2003 conv. L. 27/02/2004 n° 46 Aut. Trib. di Genova n. 75 del 22/06/1949 Divisione Italiana della International Academy of Pathology Cited in Index Medicus/MEDLINE, BIOSIS Previews, SCOPUS Journal of the Italian Society of Anatomic Pathology and Diagnostic Cytopathology, Italian Division of the International Academy of Pathology Editor-in-Chief A.G. Rizzo, Palermo Copyright Marco Chilosi, Verona G. Rossi, Modena Società Italiana di Anatomia G. Santeusanio, Roma Patologica e Citopatologia Associate Editor A. Sapino, Torino Diagnostica, Divisione Roberto Fiocca, Genova L. Saragoni, Forlì Italiana della International G.L. Taddei, Firenze Academy of Pathology Managing Editor G. Tallini, Bologna Roberto Bandelloni, Genova L. Ventura, L’Aquila Publisher Vol. 107 June 2015 G. Zamboni, Verona Pacini Editore S.p.A. 02 Scientific Board Via Gherardesca, 1 R. Alaggio, Padova Editorial Secretariat 56121 Pisa, Italy G. Angeli, Bologna M. Brunelli, Verona Tel. +39 050 313011 V. Barresi, Messina G. Martignoni, Verona Fax +39 050 3130300 A. Bondi, Bologna F. Pedica, Milano [email protected] G. Bulfamante, Milano www.pacinimedicina.it G. Cenacchi, Bologna Governing Board M. Colecchia, Milano SIAPEC-IAP P. Cossu-Rocca, Olbia President: G. d’Amati, Roma G. De Rosa, Napoli E. d’Amore, Vicenza A. D’Errico, Bologna President Elect: C. Doglioni, Milano M. Truini, Genova F. Facchetti, Brescia G. Fornaciari, Pisa General Secretary: M.P. Foschini, Bologna L. Molinaro, Torino G. Fraternali Orcioni, Genova Past President: E. Fulcheri, Genova C. Clemente, Milano W. Grigioni, Bologna M. Guido, Padova Members: L. Leoncini, Siena M. Basciu, Monza M. Lestani, Vicenza A. Bondi, Bologna G. Magro, Catania G. Botti, Napoli E. Maiorano, Bari F. Crivelli, Busto Arsizio A. Marchetti, Chieti A. Fassina, Padova G. Marucci, Bologna R. Fiocca, Genova B. Murer, Venezia A.M. Florena, Palermo O. Nappi, Napoli A. Marchetti, Chieti G. Negri, Bolzano D. Massi, Firenze A. Orlandi, Roma G. Mazzoleni, Bolzano M. Papotti, Torino L. Resta, Bari M. Paulli, Pavia G. Tinacci, Firenze G. Pelosi, Milano S. Pileri, Bologna Associate Members P. Querzoli, Ferrara Representative: L. Resta, Bari T. Zanin, Genova G. Rindi, Roma Società Italiana di Anatomia Patologica e Citopatologia Diagnostica, Divisione Italiana della International Academy of Pathology Updated information for Authors including editorial standards for the preparation of manuscripts Pathologica is intended to provide a medium for the Do not send the text in PDF. communication of results and ideas in the field of morphological Text and individual tables must be stored in separate files. research on human diseases in general and on human pathology The article must include: in particular. (1) a title (in English); The journal welcomes contributions concerned with experimental (2) an abstract (in English); morphology, ultrastructural research, immunocytochemical (3) a set of key words (in English); analysis, and molecular biology. Reports of work in other fields (4) titles and legends for all of the tables and figures. relevant to the understanding of human pathology may be The Authors are required to correct and return (within 48 hours of submitted as well all papers on the application of new methods their being sent) the first set of galley proofs of their paper. and techniques in pathology. The official language of the journal is On the first page of the manuscript should appear: Italian. Articles from foreign authors will be published in English. A concise title; a set of key words (no more than 5); the names Authors are invited to submit manuscripts according to the of the authors and the institution or organisation to which each instructions outlined below: author is affiliated; the category under which the authors intend by mail addressed to: the work to be published (although the final decision here rests Pathologica – [email protected] with the Editor-in- Chief); and the name, mailing address, and The manuscript must have the following enclosures: telephone and fax numbers of the author to whom correspondence 1) The manuscript must be submitted by e-mail to the address: and the galley proofs should be sent. [email protected] The second page should contain the abstract. At the end of the text The files containing the article, illustrations and tables must be should appear the bibliography, the legends to the tables and figures, sent in attachment and the statements of the Authors indicated at and specification (where applicable) of the congress at which all or the previous points 2 and 3 must also be enclosed or sent by air part of the data in the paper may have already been presented. mail. Tables 2) A separate covering letter, signed by every Author, must state Must be limited in number (the same data should not be presented that the material submitted has not been previously published, twice, in both the text and tables), typewritten one to a page, and and is not under consideration (in whole or in part) elsewhere, numbered consecutively with Roman numbers. In the text and and that it is conform with the regulations currently in force legend of the tables, Authors must use, in the exact order, the regarding research ethics. The Authors are solely responsible for following symbols: *, †, ‡, ¶, **, ††, ‡‡ … the statements made in their paper, and must state that they have Figures obtained the informed consent of patients for their participation Send pictures in separate files from text and tables. in the experiments and for the reproduction of photographs. For - Software and format: preferably send images in .TIFF or .JPEG studies performed on laboratory animals, the authors must state format, resolution at least 300 dpi (100 x 150 mm). Will not be that the relevant national laws or institutional guidelines have been accepted for publication manuscript with images of bad quality. adhered to. The references must be limited to the most essential and relevant Only papers that have been prepared in strict conformity with the citations, identified in the text by Arabic numbers and listed at the editorial norms outlined herein will be considered for publication. end of the manuscript in the order in which they are cited. The Their eventual acceptance is conditional upon a critical assessment format of the references in the bibliography section should conform by experts in the field, the implementation of any changes with the examples provided in N Engl J Med 1997;336:309-15. requested, and the final decision of the Editor-in-Chief. The first six Authors must be indicated, followed by et al. Journals 3) Conflict of Interests. in the letter accompanying the article, should be cited according to the abbreviations reported on Index Authors must declare if they got funds, or other forms of Medicus. personal or institutional financing – or even if they are under Examples of the correct format for bibliographic citations: contract – from Companies whose products are mentioned in the Journal articles: Jones SJ, Boyede A. Some morphological article. This declaration will be treated by the Editor-in-Chief as observations on osteoclasts. Cell Tissue Res 1977;185:387-97. confidential, and will not be sent to the referees. Accepted works Books: Taussig MJ. Processes in pathology and microbiology. will be published accompanied by a suitable declaration, stating Oxford: Blackwell 1984. the source and nature of the financing. Chapters from books: Vaughan MK. Pineal peptides: an overview. Editorial standards for the preparation of manuscripts: In Reiter RJ (ed.). The pineal gland. New York: Raven 1984:39- Pathologica will accept for publication only manuscript in English. 81. The article, in English, should be written in Microsoft Word™ Acknowledgements and information on grants or any other preferably, saving files in .RTF, .DOC or .DOCX format. Any forms of financial support must be cited at the end of the references. other programme can be used, including open source programmes: Notes to the text, indicated by an asterisk or similar symbol, please always save files in .RTF, .DOC or .DOCX format. should be shown at the bottom of the page. Do not use, under any circumstances, graphical layout programmes Mathematical terms, formulae, abbreviations, units and such as Publisher™, Pacemaker™, Quark X-press™, Adobe measures should conform to the standards set out in Science Indesign™. Do not format the text in any way (avoid styles, 1954;120:1078. borders, shading …); use only character styles such as italics, Drugs should be referred to by their chemical name; the bold, underlined. commercial name should be used only when absolutely unavoidable (capitalizing the first letter of the product name and articles or present original data. When referring to already giving the name of the pharmaceutical firm manufacturing the published articles, the letter will be sent to the authors of the drug, town and country). articles and their reply published in the same issue. They should The editorial office accepts only papers that have been prepared in not exceed 8000 characters including spaces, with one table or strict conformity with the general and specific editorial norms for figure and 2-3 references. each survey. The acceptance of the papers is subject to a critical revision by experts in the field, to the implementation of any Reprints changes requested, and to the final decision of the Editor in Chief.
Recommended publications
  • Comparative Study of Frozen Section and Squash Preparation For
    International Journal of Clinical and Diagnostic Pathology 2019; 2(1): 263-267 ISSN (P): 2617-7226 ISSN (E): 2617-7234 www.patholjournal.com Comparative study of frozen section and squash 2019; 2(1): 263-267 Received: 28-11-2018 preparation for intraoperative diagnosis of CNS Accepted: 29-12-2018 lesions and their correlation with paraffin sections in a Dr. SP Hiryur tertiary care hospital, Vadodara Associate Professor, Department of Pathology, Government Medical College, Vadodara, Gujarat, India Dr. SP Hiryur, Dr. Ushma Patel and Dr. Sivaranjini N Dr. Ushma Patel DOI: https://doi.org/10.33545/pathol.2019.v2.i1d.40 Consultant Pathologist, SNEH Pathology Laboratory, Patan, Abstract North Gujarat, India Background: The main usefulness of intraoperative consultation on lesions of the CNS is to confirm or Dr. Sivaranjini N rule out the presence or absence of neoplasia and to define the neoplastic cell type and histologic grade Resident (2nd Year), of the tumor. Two main techniques for the intra-operative diagnosis of specimens are available: Department of Pathology, cryostat (frozen) sections and smear (squash,crush) preparations. The choice of the most suitable Government Medical College, investigative technique depends on individual experience and preference. Vadodara, Gujarat, India Aims and objectives: This study aims to assess the sensitivity / diagnostic accuracy by squash preparation and frozen section, by comparing it with paraffin sections. Materials and Methods: This study comprised of 65 cases of CNS tumours received and analysed. Intraoperative squash smears and frozen sections were prepared and intraoperative diagnosis were compared with paraffin sections. Results: Out of total 65 cases, 18 cases were of Meningioma, 12 cases were of Glial Tumour and 7 cases were of Schwannoma.
    [Show full text]
  • Rapid MALDI Mass Spectrometry Imaging for Surgical Pathology
    www.nature.com/npjprecisiononcology BRIEF COMMUNICATION OPEN Rapid MALDI mass spectrometry imaging for surgical pathology Sankha S. Basu 1, Michael S. Regan2, Elizabeth C. Randall3, Walid M. Abdelmoula2, Amanda R. Clark2, Begoña Gimenez-Cassina Lopez2, Dale S. Cornett4, Andreas Haase5, Sandro Santagata1,6 and Nathalie Y. R. Agar 2,3 Matrix assisted laser desorption ionization mass spectrometry imaging (MALDI MSI) is an emerging analytical technique, which generates spatially resolved proteomic and metabolomic images from tissue specimens. Conventional MALDI MSI processing and data acquisition can take over 30 min, limiting its clinical utility for intraoperative diagnostics. We present a rapid MALDI MSI method, completed under 5 min, including sample preparation and analysis, providing a workflow compatible with the clinical frozen section procedure. npj Precision Oncology (2019) 3:17 ; https://doi.org/10.1038/s41698-019-0089-y INTRODUCTION TOF analysis in two-dimensions, the spatial distribution of The frozen section procedure dates back over a century1 and thousands of molecules within the specimen can be mapped in remains the primary mode of intraoperative tissue analysis in a single analysis. This methodology has shown tremendous nearly every operating room in the world. Briefly, the procedure potential in a variety of research applications, although lengthy involves transport of a surgical specimen to the frozen section pre-analytical processing and acquisition times (collectively 12 room, where it is rapidly frozen in embedding medium, >30 min) have limited the clinical application of MALDI MSI, a cryosectioned, stained with hematoxylin and eosin (H&E), and problem that is particularly relevant for intraoperative diagnosis microscopically assessed by an experienced pathologist.2 The by pathologists in which time is of the essence.
    [Show full text]
  • Pathologist's Role During Parathyroid Exploration In
    PATHOLOGIST’S ROLE DURING ANATOMIC PARATHYROID EXPLORATION IN A PATHOLOGY RESOURCE POOR SETTING Bimalka Seneviratne1, Bawantha Gamage2, Randi Mendis3 1. Department of Pathology / Cancer Research Centre, Faculty of Medical Sciences, University of Sri Jayewardenepura, Colombo, Sri Lanka 2. Department of Surgery, Faculty of Medical Sciences, University of Sri Jayewardenepura, Colombo, Sri Lanka 3. Histopathology division, Lanka Hospital Diagnostics, Narahenpita, Colombo, Sri Lanka INTRODUCTION Table 1: Gross examination findings of surgical (parathyroid) specimens Removal of parathyroid is recommended for patients suffering from Concordance (between Sensitivity Specificity surgeon & pathologist) hypercalcemia due to excess parathyroid hormone levels. There are Gross examination & 98% 98% >95% several causes for a hyper functioning parathyroid gland out of which identification parathyroid adenoma is the most common pathological entity. There is great variation in the number and location of parathyroid glands. Table 2: Sensitivity & specificity of intra-operative frozen section procedure In addition, the small size of parathyroid glands renders it difficult to Sensitivity Specificity Parathyroid abnormalities 100% 100% be correctly identified during surgery. Hence, intra-operative Non- parathyroid tissue (small lymph nodes, fat 100% 100% confirmation of parathyroid tissue makes it easier for the surgeon to globules & thyroid nodules in the vicinity) be confident of the outcome of the procedure and assure the patient of a permanent cure. Table
    [Show full text]
  • Frozen Section: an Overview
    Available online a t www.scholarsresearchlibrary.com Scholars Research Library Annals of Biological Research, 2012, 3 (11):5363-5366 (http://scholarsresearchlibrary.com/archive.html) ISSN 0976-1233 CODEN (USA): ABRNBW Frozen section: An overview Hamed Ganjali Ph.D Student of Histology, Veterinarian Department, Ferdowsi University of Mashhad, Iran _____________________________________________________________________________________________ ABSTRACT Frozen section is a specimen of tissue that has been quick-frozen, cut by microtome, and stained immediately for rapid diagnosis of possible malignant lesions. A specimen processed in this manner is not satisfactory for detailed study of the cells, but it is valuable because it is quick and gives the surgeon immediate information regarding the malignancy of a piece of tissue. Frozen: said of material kept at less than 0°C. Biological materials are frozen solid because of their high water con ten. Key word: frozen section, tissue, quick frozen, Microtome, surgeon. _____________________________________________________________________________________________ INTRODUCTION Frozen section A thin slice of tissue that is cut from a frozen specimen and is often used for rapid microscopic diagnosisen section and a histo logic section of tissue that has been frozen by exposure to dry ice. The frozen section procedure is a pathological laboratory procedure to perform rapid microscopic analysis of a specimen. It is used most often in on cological surgery. The technical name for this pro cedur is cryo section ( Gal AA ,2005). The quality of the slides produced by frozen section is of lower quality than formalin fixed, wax embedded tissue processing. While diagnosis can be rendered in many cases, fixed tissue processing is preferred in many conditions for more accurate diagnosis.
    [Show full text]
  • Kimianet: Training a Deep Network for Histopathology Using High-Cellularity
    KimiaNet: Training a Deep Network for Histopathology using High-Cellularity by Abtin Riasatian A thesis presented to the University of Waterloo in fulfillment of the thesis requirement for the degree of Master of Applied Science in Systems Design Engineering Waterloo, Ontario, Canada, 2020 c Abtin Riasatian 2020 Author's Declaration I hereby declare that I am the sole author of this thesis. This is a true copy of the thesis, including any required final revisions, as accepted by my examiners. I understand that my thesis may be made electronically available to the public. ii Abstract With the recent progress in deep learning, one of the common approaches to represent images is extracting deep features. A primitive way to do this is using off-the-shelf models. However, these features could be improved through fine-tuning or even training a network from scratch by domain-specific images. This desirable task is hindered by lack of annotated or labeled images in the field of histopathology. In this thesis, a new network, namely KimiaNet, is proposed that uses an existing dense topology but is tailored for generating informative and discriminative deep features from histopathology images for image representation. This model is trained based on the existing DenseNet-121 architecture but by using more than 240,000 image patches of 1000 × 1000 pixels acquired at 20× magnification. Considering the high cost of histopathology image annotation, which makes the idea impractical at the large scale, a high-cellularity mosaic approach is suggested which could be used as a weak or soft labeling method. Patches used for training the KimiaNet are extracted from 7,126 whole slide images of formalin-fixed paraffin-embedded (FFPE) biopsy samples, spanning 30 cancer sub-types and publicly available through TCGA repository.
    [Show full text]
  • Mucinous Tubular and Spindle Cell Carcinoma of the Kidney: Case
    Peter Hufnagl, diagnostic pathology 2016, 2:112 ISSN 2364-4893 DOI: http://dx.doi.org/10.17629/www.diagnosticpathology.eu-2016-2:112 Research Comparing Coventional and Telepathological Diagnosis in Routine Frozen Section Service Peter Hufnagl1*, Klaus-Dieter Winzer2, Hans Guski1, Jörg Hering3, Thomas Schrader4, Klaus Kayser1, Cornelia Tennstedt5, Manfred Dietel1 Affiliation: 1 – Institute for Pathology, Charité – Universitätsmedizin Berlin, Berlin, Germany 2 – Department of Gynecology, Charité – Universitätsmedizin Berlin, Berlin, Germany 3 – Vivantes Clinic Neukölln, Berlin, Germany 4 – University of Applied Sciences Brandenburg, Brandenburg, Germany 5 – Practice of Pathology, Mühlhausen, Germany Corresponding author: Prof. Dr. Peter Hufnagl; Institute of Pathology, Charité – Universitätsmedizin Berlin, 10098 Berlin. Abstract Aims In a prospective randomised study the diagnostic accuracy of frozen section service of conventional and telepathological procedures was compared for routine breast surgery. Material and Methods In the telepathological approach the surgeon performed the gross examination and macroscopic cutting directly supervised via videoconference by a pathologist. Then a technician prepared the frozen sections and the staining. The on-line histological diagnosis was done using a remote controlled robotic microscope. The images were transferred to the computer screen of the pathologist. In the conventional mode, the pathologist himself manually performed the gross and microscopic tissue examination in the same laboratory.
    [Show full text]
  • A Retrospective Veterinary Autopsy Study
    Stern; Frozen sections compared with paraffin-embedded sections: A retrospective veterinary autopsy study. 12 Braz J Vet Pathol, 2020, 13(1), 12 – 16 DOI: 10.24070/bjvp.1983-0246.v13i1p12-16 Original Full Paper Frozen sections compared with paraffin-embedded sections: A retrospective veterinary autopsy study Adam W. Stern Adam W. Stern, DVM, CMI-IV, CFC, DACVP, Associate Professor of Forensic Pathology, Department of Comparative, Diagnostic, and Population Medicine, College of Veterinary Medicine, University of Florida, 2015 SW 16th Avenue, Gainesville, FL 32608. E-mail: [email protected] Submitted June, 25th 2019, Accepted December, 23th 2019 Abstract Histologic examination of tissues collected at autopsy are typically prepared using conventional methods (formalin fixed, paraffin‐embedded tissue). In this study, twenty-five tissue specimens from twelve animals were collected at autopsy and examined using the frozen section technique. Of the 25 specimens examined, an accurate and specific diagnosis was obtained in 21 specimens; the pathologic process was correctly identified, but a specific diagnosis was not obtained in 1 specimen; the diagnosis was missed in 2 specimens, and in 1 specimen the diagnosis was deferred. Of the two incorrect diagnoses, one was due to a sampling error and one was due to an interpretation error. Overall, the use of postmortem frozen sections allowed for complete agreement with conventional methods in 21 specimens (84%) and the results from this study support the use of frozen section examination of tissue samples collected postmortem. Key words: frozen section procedure, cryosection, histopathology, postmortem Introduction histopathology. Frozen section histology has many uses including the ability to establish the presence of a lesion, Postmortem examinations are performed for a establish the nature of a lesion, and determine the number of reasons including determination of the cause of adequacy of margins (5).
    [Show full text]
  • Validation of Frozen Section in Intraoperative Decision Making in Malignancies”Is a Bonafide Work Done by Dr
    Validation of frozen section in intraoperative decision making in malignancies Dept of Surgical Oncology Centre for Oncology Govt. Royapettah hospital Kilpauk Medical College Dissertation submitted in partial fulfillment of the Requirement for the award of degree of MChBranch VII (Surgical Oncology) AUGUST 2014 TAMIL NADU DR. MGR MEDICAL UNIVERSITY CHENNAI- 600032 CERTIFICATE This is to certify that the dissertation entitled “Validation of frozen section in Intraoperative decision making in malignancies”is a bonafide work done by Dr. K. Kavitha , Department of Surgical Oncology, Centre for Oncology, Government Royapettah hospital and Kilpauk Medical College , Chennai, in partial fulfillment of the University rules and regulations , for the award of M.Ch.Degree (Branch VII) in Surgical Oncology , under my guidance and supervision during the academic yearAugust 2011 to August 2014. Prof .Dr.R.Rajaraman, MS., MCh Guide , Professor and Head Department of Surgical Oncology Centre for Oncology Government Royapettah Hospital & Kilpauk Medical College Chennai Dean Kilpauk Medical College Chennai – 10 DECLARATION I solemnly declare that the dissertation titled “Validation of frozen section in intraoperative decision making in malignancies was done by me at Department of Surgical Oncology, Kilpauk Medical College andGovernment Royapettah Hospital, Chennai between August 2011 to February 2014 under theguidance and supervision of Prof. Dr. R.Rajaraman. The Dissertation is submitted to The TamilNaduDr.M.G.R. Medical University towards the partial fulfillment
    [Show full text]
  • Scientific Article
    SCIENTIFIC ARTICLE Role of routine frozen sections for parathyroid exploration in a resource poor setting U. Bimalka Seneviratne1, Bawantha Gamage2 1Department of Pathology / Cancer Research Centre, Faculty of Medical Sciences, University of Sri Jayewardenepura 2Department of Surgery, Faculty of Medical Sciences, University of Sri Jayewardenepura Key words: Parathyroid; frozen section diagnosisl Introduction parathyroid hormone Parathyroid glands were discovered for the first time in 1852 by Richard Owen in Indian rhinoceros (1). In 1880 a Swedish Abstract medical student at the Uppsala University noted its existence Removal of parathyroid is recommended for patients in humans, dogs, cats, horses and rabbits (2, 3). Removal of suffering from hypercalcemia due to excess parathyroid parathyroid dates back to 1928 and Isaac Y Olch, a medical hormone levels. There are several causes for a doctor had been acknowledged for performing parathyroid hyperfunctioning parathyroid gland out of which parathyroid surgery for the first time in human beings (4). adenoma is the most common pathological entity. There is great variation in the number and location of parathyroid Parathyroid glands are usually located on the posterior aspect glands. Hence, intra-operative confirmation of parathyroid of the right and left lobes of thyroid, but separated from it by a tissue makes it easier for the surgeon to be confident of the delicate connective tissue capsule. Parathyroid glands are outcome of the procedure and assure the patient of a known to be derivatives of 3rd and 4th branchial pouches of permanent cure. the primitive foregut during embryogenesis (5). There are two pairs of parathyroid glands; superior and inferior. The vast A descriptive cross sectional study was done in a cohort of 26 majority has four glands although there is variation in the patients who presented with elevated total serum calcium and number (6).
    [Show full text]
  • Correlation of Intraoperative Frozen Section Report and Histopathological Diagnosis
    Original Research Article Correlation of intraoperative frozen section report and histopathological diagnosis Hiral Samir Shah1, Meena Rajiv Daveshwar2*, Neema Ankur Rana3 1Tutor, 2Associate Professor,3Assistant Professor, Pathology Department, SSG Hospital and Medical College, Baroda- 390001. Gujarat, INDIA. Email: [email protected] Abstract Frozen section (FS) is an accurate and reliable test for intraoperative consultation. More accurate sampling plus better communication between pathologist and surgeon is recommended to help reducing the rate of discordant and deferral cases. Frozen section is subject to various limitations which both surgeon and pathologist should keep in mind when ordering and performing the procedure. The present study reviewed 264 tissues of 110 cases of frozen section biopsy, to assess the indication, accuracy and discrepancies in morphological examination to diagnose normal, nonneoplastic and neoplastic lesions. When FS were compared with paraffin sections, seven cases were discordant that included three cases of false negative(1.1%) and four cases of false positive (1.5%) diagnosis on frozen section. Key Words: Frozen section, Histopathology, Intraoperative consultation. *Address for Correspondence: Dr. Meena Rajiv Daveshwar, 18, Yantrika Society, Near Chanakyapuri, New Sama Road, Vadodara, Gujarat. 390024. Email: [email protected] Received Date: 20/10/2019 Revised Date: 17/11/2019 Accepted Date: 12/12/2019 DOI: https://doi.org/10.26611/1051239 confirmation of presence of representative samples for Access this article online paraffin section diagnosis and to determine further surgical treatment protocols.5,6 Quick Response Code: Website: www.medpulse.in MATERIALS AND METHODS It was a prospective analysis of 264 tissues of 110 cases of frozen section procedure. The gross specimens were Accessed Date: cut into thin slices and examined.
    [Show full text]
  • Experience with a Dynamic Inexpensive Video-Conferencing System for Frozen Section Telepathology 1
    169 Experience with a dynamic inexpensive video-conferencing system for frozen section telepathology 1 ∗ J.P.A. Baak a,b, , P.J. van Diest a and G.A. Meijer a there was a clear learning effect: 5 of the 8 FS/TP discrepan- cies occurred in the first 42 cases (5/42 = 11.9%), the re- a Department of Pathology, University Hospital VU, maining 3 in the following 86 cases (3/86 = 3.5%). Discus- sion: The results are encouraging. However, TP evaluation is Amsterdam, The Netherlands b time-consuming (5–15 min for one case instead of 2–4 min Department of Pathology, Medisch Centrum although speed went up with more experience) and is more Alkmaar, Alkmaar, The Netherlands tiring. The system has the following technical drawbacks: no possibility to point at objects or areas of interest in the life Aim: To evaluate the feasibility of an inexpensive, gener- image at the other end, resolution (rarely) may become sub- ally applicable video-conferencing system for frozen section optimal (blocky), storage of images evaluated (which is es- telepathology (TP). Methods: A commercially widely avail- sential for legal reasons) is not easy and no direct control of able PC-based dynamic video-conferencing system (Picture- a remote motorized microscope. Yet, all users were positive Tel LIVE, model PCS 100) has been evaluated, using two, about the system both for telepathology and personal contact four and six ISDN channels (128–384 kilobits per second by video-conferencing. Conclusion: With a relatively simple (kbs)) bandwidths. 129 frozen sections have been analyzed videoconferencing system, accurate dynamic telepathology which were classified by TP as benign, uncertain (the remark frozen section diagnosis can be obtained without false posi- probably benign, or probably malignant was allowed), ma- tive or negative results, although a limited number of uncer- lignant, or not acceptable image quality.
    [Show full text]
  • Cardiophrenic Lymph Nodes
    E-PÔSTER XIV Congresso Brasileiro de Cirurgia Oncológica TEMÁRIO: CIRURGIA CITORREDUTORA / HIPEC disease, as well as the higher risk of postoperative CÓDIGO: 88345 complications. CARDIOPHRENIC LYMPH NODES: WHAT IS Contato: Mariana Sousa Arakaki THEIR VALUE IN PATIENTS WITH PERITONEAL [email protected] CARCINOMATOSIS? WHAT CHANGES IN THE MANAGEMENT AND PROGNOSIS OF THESE TEMÁRIO: CIRURGIA CITORREDUTORA / HIPEC PATIENTS? CÓDIGO: 87883 Autores: Eduardo Hiroshi Akaishi / Akaishi, E. H. / Hospital das Clínicas da FMUSP; Mariana Sousa Arakaki CYTOREDUCTIVE SURGERY WITH CHEMO- / Arakaki, M. S. / Hospital das Clínicas da FMUSP; Helber THERAPY INTRAPERITONEAL HYPERTEN- Vidal Gadelha Lima / Lima, H. V. G. / Hospital das Clínicas SION (HIPEC) WITH PARTIAL HEPATECTOMY da FMUSP; Ivan Vinicius Andrade Galindo / Galindo, I. BY METASTATIC RIGHT COLON ADENOCAR- V. A. / A.C.Camargo Cancer Center; Lucas Afonso Daia CINOMA / Daia, L. A. / Hospital das Clínicas da FMUSP; Tomas Mansur Duarte de Miranda Marques / Marques, T. M. Autores: Matheus Pingerno dos Santos / SANTOS, M. D. M. / A.C.Camargo Cancer Center; Edivaldo Massazo P. / Universidade do Sul de Santa Catarina - UNISUL; Utiyama / Utiyama, E. M. / Hospital das Clínicas da Ariane Elias Antunes / ANTUNES, A. E / Universidade do FMUSP. Sul de Santa Catarina - UNISUL; Lucas Camargo Gamba Martins Do Amaral / AMARAL, L. C. G. M. / Universidade Introduction: Most primary tumors that occur within do Sul de Santa Catarina - UNISUL; Murilo Jebai the abdominal cavity can spread via hematogenous, Monteiro / MONTEIRO, M. J. / Universidade do Sul de lymphatic and peritoneal implantation. In the past, Santa Catarina - UNISUL; Italo Mattos Rinaldi / RINALDI, peritoneal carcinomatosis was considered fatal, I. M. / Universidade do Sul de Santa Catarina - UNISUL; causing intestinal obstruction and death in months Beatriz de Oliveira Kock / KOCK, B.
    [Show full text]