The Cigarette Century
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Richard Doll
2825 Obituary: Richard Doll Sir Richard Doll died earlier this year at age 92. The most The studies by Doll are bold and original science. They celebrated epidemiologist of the 20th century, Doll is best represent an important part of the foundation of modern known for his work on smoking and lung cancer, but there was population-based chronic disease research. By the early 1960s, so much more to his career. they constituted adequate evidence for public health action to His father was a general practitioner in London, and it was reduce tobacco smoking; in 1964, the U.S. Surgeon General’s from St. Thomas’s that Doll himself graduated in Medicine in first report on the adverse health consequences of tobacco was 1937. Even as a student, he showed his interest in epidemi- published. Today, they continue to remind us how carefully ologic and statistical tools, publishing on the need for proper crafted observational studies can advance scientific knowledge analysis and statistical testing in population studies of disease. regarding social and health issues that are not amenable to Later, Doll served in the Royal Medical Corps in France and experimentation on human populations. the Middle East throughout the Second World War. He began Asbestos. By the early 1930s, work in the asbestos products his research career at the Middlesex Hospital, studying industry in Britain was known to increase the risk of a occupational factors in the development of peptic ulceration. sometimes fatal nonmalignant pulmonary disease, termed He married Dr. Joan Faulkner around this time, and it was she asbestosis. -
Date of Preparation October 1, 2020 Format of This CV: Committee On
Date of Preparation October 1, 2020 Format of this CV: Committee on Appointments and Promotions Mailman School of Public Health, Columbia University Personal data Steven D. Stellman Birthdate: May 7, 1945 Birthplace: Toronto, Canada Citizenship: USA Academic appointments 1966-71 Teaching Fellow, Department of Chemistry, New York University 1971-73 Research Associate, Division of Biochemical Sciences, Princeton University 1973-74 Lecturer in Chemistry, University of Colorado, Denver 1978-82 Adjunct Associate Professor, Hunter College of the City University of New York, Depts. of Chemistry and Environmental Health Sciences 1979-82 Adjunct Associate Professor, Dept. of Research Medicine, University of Pennsylvania School of Medicine 1980-81 Adjunct Associate Professor, Dept. of Epidemiology, Cornell University School of Medicine 1981-94 Adjunct Associate Professor, Dept. of Community Medicine, Mt. Sinai School of Medicine, New York, NY 2000 - Professor of Clinical Epidemiology, Mailman School of Public Health, Columbia University; Assoc Chair, 2016- Education Ohio State University, B.Sc. 09/1964 to 06/1966, Chemistry. New York University, Ph.D. 09/1966 to 1971, Physical chemistry. Thesis title: Computer simulation of polymer conformation and conformational thermodynamics. Sponsor: Paul J. Gans, Ph.D. Citations: (1) Stellman SD, Froimowitz M, Gans PJ. J Computational Physics 1971; 7:179-182. (2) Stellman SD, Gans PJ. Macromolecules 1972; 5:516-526. (3) Stellman SD, Gans PJ. Macromolecules 1972; 5:720-729. Columbia University, M.P.H., 09/1990 to 06/1992, Executive MPH Program in Health Policy & Management Traineeships 1968-71 New York University, National Science Foundation Graduate Traineeship 1971-73 Princeton University, Post-doctoral fellow, Dept. of Biochemical Sciences Professional organizations and societies Society for Epidemiologic Research American College of Epidemiology American Public Health Association American Chemical Society American Society of Preventive Oncology Steven D. -
The P53 Tumour Suppressor Gene and the Tobacco Industry
Lancet Manuscript 03ART/3495 Revised 1 The p53 Tumor Suppressor Gene and the Tobacco Industry: Research, Debate, and Conflict of Interest Asaf Bitton, BA Mark D. Neuman, BA Joaquin Barnoya, MD MPH Stanton A. Glantz, PhD Center for Tobacco Control Research and Education University of California, San Francisco San Francisco, CA 94143 This work was supported by National Cancer Institute Grant CA-87472 and the American Legacy Foundation. Address for correspondence and Reprints: Stanton A. Glantz, PhD Professor of Medicine Box 1390 University of California San Francisco, CA 94143 415-476-3893 fax 415-514-9345 [email protected] Lancet Manuscript 03ART/3495 Revised 2 Summary Background: Mutations in the p53 tumor suppressor gene lead to uncontrolled cell division and are found in over 50% of all human tumors, including 60% of lung cancers. Research published in 1996 by Mikhail Denissenko et al. demonstrated patterned in vitro mutagenic effects on p53 of benzo[a]pyrene, a carcinogen present in tobacco smoke. We investigate the tobacco industry’s strategies in responding to p53 research linking smoking to cancer. Methods: We searched online tobacco document archives, including the Legacy Tobacco Documents Library and Tobacco Documents Online, and archives maintained by tobacco companies such as Philip Morris and RJ Reynolds. Documents were also obtained from the British American Tobacco Company depository near Guildford, England. Informal correspondence was carried out with scientists, lawyers, and tobacco control experts in the United States and Europe. Findings: Individuals at the highest levels of the tobacco industry anticipated and carefully monitored p53 research. Tobacco scientists conducted research intended to cast doubt on the link between smoking and p53 mutations. -
A Frank Statement to Cigarette Smokers 1
1 A FRANK STATEMENT TO CIGARETTE SMOKERS Recent reports on experiments with mice have given wide publicity to the theory that cigarette smoking is in some way linked with lung cancer in human beings. Although conducted by doctors of professional standing, these experiments are not regarded as conclusive in the field of cancer research. However, we do not believe that any serious medical research, even though its results are inconclusive, should be disregarded or lightly dismissed. At the same time, we feel it is in the public interest to call attention to the fact that eminent doctors and research scientists have publicly questioned the claimed significance of these experiments. Distinguished authorities point out: 1. That medical research of recent years indicates many possible causes of lung cancer. 2. That there is no agreement among the authorities regarding what the cause is. 3. That there is no proof that cigarette smoking is one of the causes. 4. That statistics purporting to link cigarette smoking with the disease could apply with equal force to any one of many other aspects of modern life. Indeed, the validity of the statistics themselves is questioned by numerous scientists. We accept an interest in people’s health as a basic responsibility, paramount to every other consideration in our business. We believe the products we make are not injurious to health. We always have and always will cooperate closely with those whose task it is to safeguard the public health. For more than 300 years tobacco has given solace, relaxation and enjoyment to mankind. At one time or another during those years critics have held it responsible for practically every disease of the human body. -
Tobacco Control
TOBACCO CONTROL Playbook World Health Organization ABSTRACT Tobacco control is difficult and complex and obstructed by the tactics of the tobacco industry and its allies to oppose effective tobacco control measures. This document was developed by the WHO Regional Office for Europe by collecting numerous evidence-based arguments from different thematic areas, reflecting the challenges that tobacco control leaders have faced while implementing various articles of the WHO FCTC and highlighting arguments they have developed in order to counter and succeed against the tobacco industry. KEY WORDS TOBACCO CONTROL WHO FCTC HEALTH EFFECTS TOBACCO INDUSTRY ARGUMENTS © World Health Organization 2019 All rights reserved. The Regional Office for Europe of the World Health Organization welcomes requests for permission to reproduce or translate its publications, in part or in full. The designations employed and the presentation of the material in this publication do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted lines on maps represent approximate border lines for which there may not yet be full agreement. The mention of specific companies or of certain manufacturers’ products does not imply that they are endorsed or recommended by the World Health Organization in preference to others of a similar nature that are not mentioned. Errors and omissions excepted, the names of proprietary products are distinguished by initial capital letters. All reasonable precautions have been taken by the World Health Organization to verify the information contained in this publication. -
Amicus Curiae Public Health Advocacy Institute in Support of Appellants
COMMONWEALTH OF MASSACHUSETTS SUPREME JUDICIAL COURT FOR THE COMMONWEALTH OF MASSACHUSETTS No. SJC-11641 ___________________________ STEVEN P. ABDOW, STEPHANIE C. CRIMMONS, JOSEPH A. CURATONE, GERI EDDINS, MARK A. GOTTLIEB, CELESTE B. MEYERS, KRISTIAN M. MINEAU, KATHLEEN CONLEY NORBUT, JOHN F. RIBEIRO, and SUSAN C. TUCKER, Plaintiffs/Appellants v. GEORGE DUCHARME, ET AL., DANIEL RIZZO, ET AL., and DOMENIC J. SARNO, ET AL., Interveners/Appellants, v. ATTORNEY GENERAL and SECRETARY OF THE COMMONWEALTH, Defendants/Appellees. ___________________________ BRIEF OF AMICUS CURIAE PUBLIC HEALTH ADVOCACY INSTITUTE IN SUPPORT OF APPELLANTS ___________________________ Edward L. Sweda, Jr. BBO #489820 Public Health Advocacy Institute 360 Huntington Ave., 117 CU Boston, MA 02115 (617) 373-2026 Counsel for the Public Health Advocacy Institute TABLE OF CONTENTS TABLE OF AUTHORITIES................................ ii CORPORATE DISCLOSURE STATEMENT....................... 1 STATEMENT OF INTEREST OF THE AMICI CURIAE............ 1 INTRODUCTION......................................... 2 SUMMARY OF ARGUMENT.................................. 4 ARGUMENT............................................. 6 CONCLUSION.......................................... 42 CERTIFICATE OF COMPLIANCE WITH MASS. R. APP. P. 16(k) .................................................... 44 i TABLE OF AUTHORITIES Cases Aspinall v. Philip Morris Cos., Inc., 2014 Mass. Super. LEXIS 26 (Mass. 2014) ....................................................... 15 Donovan v. Philip Morris USA, Inc., -
AATS Graham Foundation
AATS GRAHAM FOUNDATION 1973-2013 40YEARS OF SUPPORTING DRIVING LEADERSHIP, LEARNING AND INNOVATION IN THE PURSUIT OF EXCELLENCE 2013 ANNUAL REPORT Excellence! 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 40 -
The Origins, Development, Effects, and Future of the WHO Framework
Viewpoint The origins, development, eff ects, and future of the WHO Framework Convention on Tobacco Control: a personal perspective Derek Yach Worldwide, more than 1 billion people use tobacco, resulting in about 6 million deaths per year. The tobacco Lancet 2014; 383: 1771–79 industry’s documented history of subverting control eff orts required innovative approaches by WHO—led by Published Online Gro Harlem Brundtland—including invocation of its constitutional authority to develop treaties. In 2003, WHO January 22, 2014 member states adopted the WHO Framework Convention on Tobacco Control (WHO FCTC). In the decade since, http://dx.doi.org/10.1016/ S0140-6736(13)62155-8 177 countries have ratifi ed and started to implement its full provisions. Success has been tempered by new challenges. The Vitality Institute, New York, Tobacco use has fallen in countries that are members of the Organisation for Economic Co-operation and Development NY, USA (D Yach MBChB) but increased in low-income and middle-income countries, a result in no small part of illicit trade and cheap products Correspondence to: from China and other unregulated state monopolies. This review of 50 years of policy development aimed at reducing Derek Yach, 3 Columbus Circle, the burden of disease attributable to tobacco reviews the origins and strategies used in forging the WHO FCTC, from Suite 1656, New York, NY 10019, the perspective of one who was there. USA [email protected] Introduction advertising of tobacco products beginning in 1971 and In 1954, the tobacco industry issued A Frank Statement to campaigns to protect non-smokers from exposure to Cigarette Smokers,1 claiming, “we believe the products we second-hand smoke. -
A “Frank Statement” for the 21St Century?
Editorial Tob Control: first published as 10.1136/tobaccocontrol-2017-054080 on 24 October 2017. Downloaded from industry pig, but in a way it’s far worse A “Frank Statement” for the this time: by using a formerly high profile WHO leader as a spokesperson, PMI can 21st Century? also accelerate its longstanding ambition to splinter the tobacco control movement.5 Ruth E Malone,1 Simon Chapman,2 Prakash C Gupta,3 It’s also not true, as the video suggests, 4 5 6 7 that tobacco control efforts have Rima Nakkash, Tih Ntiabang, Eduardo Bianco, Yussuf Saloojee, “plateaued.” Cigarette consumption is 8 9 9 10 Prakit Vathesatogkit, Laurent Huber, Chris Bostic, Pascal Diethelm, declining and since 2003, more than Cynthia Callard,11 Neil Collishaw,11 Anna B Gilmore12 180 countries have become parties to the WHO Framework Convention on Tobacco Control (FCTC), committing The surprise announcement by the former from having any influence over how the themselves to implement effective policy head of the WHO’s Tobacco Free Initia- Foundation spends its funds or focuses its measures and building public support for 2 tive, Derek Yach, that he would head a activities.’ ending the epidemic. PMI knows this, newly-established organisation called the Except that is what a broad range of hence its ongoing, covert and overt efforts 1 ‘Foundation for a Smoke-free World’ to industry front groups, sometimes headed to stymie the FCTC.6 ‘accelerate the end of smoking’ was met by respected and even well-intentioned For example, at the last Conference of with gut-punched disappointment by leaders, have been saying since the ‘Frank the Parties, the meetings where implemen- 3 those who have worked for decades to Statement’ of 1954. -
How Americans Learned About the Dangers of Cigarette Smoking In: the Case of Florida
ATINER CONFERENCE PRESENTATION SERIES No: HUM2017-0002 ATINER’s Conference Paper Proceedings Series HUM2017-0002 Athens, 18 January 2017 How Americans Learned about the Dangers of Cigarette Smoking in: The Case of Florida Terry Parssinen Athens Institute for Education and Research 8 Valaoritou Street, Kolonaki, 10683 Athens, Greece ATINER’s conference paper proceedings series are circulated to promote dialogue among academic scholars. All papers of this series have been blind reviewed and accepted for presentation at one of ATINER’s annual conferences according to its acceptance policies (http://www.atiner.gr/acceptance). © All rights reserved by authors. 1 ATINER CONFERENCE PRESENTATION SERIES No: HUM2017-0002 ATINER’s Conference Paper Proceedings Series HUM2017-0002 Athens, 18 January 2017 ISSN: 2529-167X Terry Parssinen, PhD, Professor of History, University of Tampa,USA How Americans Learned about the Dangers of Cigarette Smoking in: The Case of Florida ABSTRACT The rate of cigarette smoking in America from the 1950s until the present has dropped from 44% to about 18%. The causes of this decline can be traced to concrete measures such as the prohibition of smoking in public areas, and the increase in cigarette taxes, making it more expensive for regular smokers to maintain their habits. However, underlying these changes has been a growing awareness of the health dangers from smoking. From 1950 until 1964, medical and scientific researchers announced the results of experiments and survey data that showed a strong positive correlation between cigarette smoking and various diseases, beginning with lung cancer, but eventually including COPD, heart disease, and other forms of cancer. -
The Adverse Health Effects of Smoking and the Tobacco Industry’S Efforts to Limit Tobacco Control
THE ADVERSE HEALTH EFFECTS OF SMOKING AND THE TOBACCO INDUSTRY’S EFFORTS TO LIMIT TOBACCO CONTROL Prepared by: Jonathan M. Samet, MD, MS Director, USC Institute for Global Health Distinguished Professor and Flora L. Thornton Chair, Department of Preventive Medicine, Keck School of Medicine of USC University of Southern California 2001 North Soto Street, Suite 330A Los Angeles, California 90089-9239, USA Phone: +1 323 865 0803 Fax: +1 323 865 0854 Email: [email protected] 1 Table of Contents Summary ....................................................................................................................................................... 4 Professional Qualifications ........................................................................................................................... 6 Approach ....................................................................................................................................................... 9 Introduction and Context ............................................................................................................................ 10 Scientific approaches to smoking and health ......................................................................................... 11 Epidemiological research ........................................................................................................................ 14 Identifying causes of disease................................................................................................................... 15 The -
Failed Promises of the Cigarette Industry and Its Effect on Consumer Misperceptions About the Health Risks of Smoking K M Cummings, C P Morley, a Hyland
i110 Tob Control: first published as 10.1136/tc.11.suppl_1.i110 on 1 March 2002. Downloaded from Failed promises of the cigarette industry and its effect on consumer misperceptions about the health risks of smoking K M Cummings, C P Morley, A Hyland ............................................................................................................................. Tobacco Control 2002;11(Suppl I):i110–i117 Background: In January 1954, US tobacco manufacturers jointly sponsored an advocacy advertise- ment entitled “A Frank Statement to Cigarette Smokers” which appeared in 448 newspapers in 258 cities reaching an estimated 43 245 000 Americans. The advertisement questioned research findings implicating smoking as a cause of cancer, promised consumers that their cigarettes were safe, and pledged to support impartial research to investigate allegations that smoking was harmful to human health. Objective: To examine (1) the extent to which cigarette companies fulfilled the promises made to con- sumers in the 1954 “Frank Statement”, and (2) the effect of these promises on consumer knowledge, beliefs, and smoking practices. Methods: This study reviews statements made since 1954 by the tobacco companies individually and collectively through the Tobacco Institute and Tobacco Industry Research Committee/Council for Tobacco Research on the subject of smoking as a cause disease, and the industry’s pledge to support and disclose the results of impartial research on smoking and health. Many of the industry documents evaluated in this study were obtained from a collection consisting of 116 documents entitled the “State- ment of Defendants’ Misrepresentations” prepared by attorneys representing the state of Connecticut in the Medicaid litigation against the tobacco industry in 1998. In addition, we searched for corroborat- ing material from tobacco industry documents collected from the tobacco industry’s document websites.