International Journal of Environmental Research and Public Health Article Maternal Prepregnancy Body Mass Index, Gestational Weight Gain, and Risk of Adverse Perinatal Outcomes in Taiwan: A Population-Based Birth Cohort Study Chi-Nien Chen 1,* , Ho-Sheng Chen 2,3 and Heng-Cheng Hsu 4,5 1 Department of Pediatrics, National Taiwan University Hospital Hsinchu Branch, Hsinchu 30059, Taiwan 2 Department of Pediatrics, National Taiwan University Children’s Hospital, Taipei 10041, Taiwan;
[email protected] 3 Department of Emergency, National Taiwan University Hospital, Taipei 10048, Taiwan 4 Department of Obstetrics and Gynecology, National Taiwan University Hospital Hsinchu Branch, Hsinchu 30059, Taiwan;
[email protected] 5 Department of Obstetrics and Gynecology, National Taiwan University Hospital, Taipei 10048, Taiwan * Correspondence:
[email protected] Received: 30 December 2019; Accepted: 12 February 2020; Published: 14 February 2020 Abstract: Epidemiological studies have shown that maternal prepregnancy body mass index (BMI) and gestational weight gain (GWG) are associated with increased risk of perinatal outcomes. However, the evidence of such associations in Asian populations is limited. We conducted a secondary data analysis to investigate the relationships of prepregnancy BMI and GWG with the risks of adverse perinatal outcomes, including gestational diabetes (GDM), gestational hypertension (GHTN), preeclampsia, cesarean delivery, preterm birth, low birth weight (LBW), and macrosomia. We categorized prepregnancy BMI by the WHO classification and GWG by the Institute of Medicine guidelines. We performed adjusted logistic regression models to estimate the odds ratios of adverse perinatal outcomes. A total of 19,052 women were included; prepregnancy overweight and obesity were associated with a greater risk of GDM, GHTN, preeclampsia, cesarean delivery, preterm birth, and macrosomia.