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Transitional Features of Acute Herpetic Stomatitis in Children and Modern Approaches to Treatment

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Transitional Features of Acute Herpetic Stomatitis in Children and Modern Approaches to Treatment NOVATEUR PUBLICATIONS JournalNX- A Multidisciplinary Peer Reviewed Journal ISSN No: 2581 - 4230 VOLUME 6, ISSUE 9, Sep. -2020 TRANSITIONAL FEATURES OF ACUTE HERPETIC STOMATITIS IN CHILDREN AND MODERN APPROACHES TO TREATMENT UMAROVA ODINAHON NUMANOVNA Andijan State Medical Institute, Faculty of Dentistry and Assistant of the Department of Propaedeutics of Dental Diseases Phon: +99891 6166658, e-mail: [email protected] ABSTRACT: Herpetic stomatitis Herpesviruses are widespread us in Herpetic stomatitis is a viral infection of the human population. They capable of the mouth that causes sores and ulcers. These hitting almost everyone organs and systems, mouth ulcers are not the same as canker sores, induce neoplastic static processes and which are not caused by a virus. development of atherosclerosis, have an Gingivostomatitis is a highly contagious adverse effect, and sometimes a fatal effect infection of the mouth. Its main symptoms on the body nism of the fetus and include pain, swollen gums, blisters, and sores. newborns.The article presents These sores can develop on the tongue, under characteristic peculiarities of herpetic the tongue, and on the cheeks inside the mouth, stomatitis in children. It describes as well as on the lips and gums. It usually differential diagnostic symptoms. The spreads through the saliva of an infected treatment approaches are given depending individual or by direct contact with a lesion or on the severity degree of the disease. sore. KEYWORDS: herpes virus, infection, Gingivostomatitis is most common in groprinosin, Oral infection, young children, usually under 6 years old, but gingivostomatitis. can also occur in adults. Older people may experience more severe symptoms. INTRODUCTION: Gingivostomatitis is sometimes called herpetic Herpetic gingivostomatitis is a stomatitis because it is usually the result of manifestation of herpes simplex virus type 1 infection by the herpes simplex virus. Herpes (HSV-1) and is characterized by high-grade simplex also causes cold sores. However, it is fever and painful oral lesions. While herpetic important to note that many different factors gingivostomatitis most commonly occurs in can cause the irritation and sores in the mouth children from ages 6 months to 5 years, it may that are characteristic of gingivostomatitis. also occur in adults. HSV-1 is usually spread The general medical term for from direct contact or via droplets of oral inflammation of the mouth and lips is secretions or lesions from an asymptomatic or stomatitis. Factors that can cause stomatitis symptomatic individual. Once a patient is include: herpes viruses enteroviruses, such as infected with the herpes simplex virus, the the coxsackievirus, bacteria, allergies, exposure infection can recur in the form of herpes to irritating chemicals or other substances, labialis (cold sores) with intermittent re- radiation and chemotherapy activation occurring throughout life. Symptoms 123 | P a g e NOVATEUR PUBLICATIONS JournalNX- A Multidisciplinary Peer Reviewed Journal ISSN No: 2581 - 4230 VOLUME 6, ISSUE 9, Sep. -2020 MATERIALS AND METHODS: DNA genome. HSV-1 is mostly responsible for The symptoms of gingivostomatitis oral, ocular, and facial infections as it has a include: pain around the gums and mouth, red, tropism for oral epithelium. While most cases swollen gums blisters on the gums, lips, tongue, of herpetic gingivostomatitis are associated cheeks, and roof of the mouth, ulcers in the with HSV-1 infection, some adult cases have mouth, fever, drooling, especially in children, been reported where HSV-2 was isolated from bad breath, and reluctance to eat or drink. the oral lesions. Oral infection with HSV-2 is Some cases of gingivostomatitis may be probably transmitted through orogenital subclinical, which means that the symptoms contact and has also been observed in HIV- are not severe, or easy to identify and diagnose. positive patients and patients undergoing In other cases, some individuals may go immunosuppressive therapy. through a period of feeling feverish and having Epidemiology general malaise before the sores develop. Primary herpetic gingivostomatitis Swollen gums and sores in the mouth make typically occurs in children younger than the eating and drinking uncomfortable. This can age of 5 years, but can also occur in adolescents cause children to refuse food and drinks. One and adults. HSV-1 is usually acquired in study found that 89 percent of children with childhood by coming into contact with the oral gingivostomatitis drank less than usual. To secretions. It is estimated that almost 90% of prevent dehydration and poor nutrition, adults ¥®• Ø≤¨§ï≥ Ø∞µ¨°¥©Øn is seropositive for HSV- ≥®Øµ¨§ ØÆ©¥Ø≤ £®©¨§≤•Æï≥ £ØÆ≥µ≠¥©ØÆ °Æ§ 1 by 35 years of age, and half of the individuals ensure they are getting enough fluids. carrying the virus will experience reactivation Adopting a diet consisting of soft foods in the form of herpes labialis. Herpetic and avoiding citrus or carbonated beverages gingivostomatitis is equally distributed can help. In some cases, a person can apply amongst gender and race groups and is not numbing medication to provide relief at found to have a particular seasonal or mealtimes. geographic distribution. DISCUSSION AND ACKNOWLEDGEMENT: Treatment: Causes: Treating gingivostomatitis focuses on Herpetic stomatitis is an infection providing relief from the painful symptoms and caused by the herpes simplex virus (HSV), or getting rid of the infection. oral herpes. Young children commonly get it Standard ways to reduce the discomfort when they are first exposed to HSV. The first associated with gingivostomatitis include: outbreak is usually the most severe. HSV can Taking over-the-counter pain relievers, easily be spread from one child to another. If as directed rinsing the mouth with a saltwater you or another adult in the family has a cold solution (1/2 teaspoon of salt in 1 cup of warm sore, it could have spread to your child and water) using medicinal mouthwashes drinking caused herpetic stomatitis. More likely, you plenty of water; eating soft, bland foods, such won't know how your child became infected. as applesauce, mashed bananas, and warm Etiology oatmeal, that make eating less painful. The causative agent is Herpes simplex A doctor may also prescribe acyclovir, virus type 1 (HSV-1), which belongs to the which also helps treat chickenpox, herpes alphaherpesvirus group. The virus is simplex, and shingles. Studies have found that enveloped and has a linear double-stranded the use of acyclovir: 124 | P a g e NOVATEUR PUBLICATIONS JournalNX- A Multidisciplinary Peer Reviewed Journal ISSN No: 2581 - 4230 VOLUME 6, ISSUE 9, Sep. -2020 shortened the duration of symptoms by immunobiological drugs. Immunomodulators 2050 percent led to more rapid healing of are prescribed in the acute period of the sores helped people return to regular eating disease and in the early stage convalescence, and drinking habits faster. and later - for prevention of relapse. Symptoms of gingivostomatitis usually As an etiotropic therapy for of disappear without medical treatment within 1 herpesvirus infections in many European to 2 weeks, but the infection may recur. People countries and the Republic of Belarus also need to take steps to prevent the spread of Groprinosin is used successfully. gingivostomatitis, particularly among young Groprinosin (inosine pranobex) - children. The condition spreads through saliva complex synthetic preparation, possessing and by touching the sores, so it is sensible to universal immuno- modulating properties and try to avoid close contact with infected people, direct antiviral activity: and not to allow children with Enhances differentiation T lymphocytes to gingivostomatitis to share toys or personal killer T cells; items. Modulates the relationship between T- OGS treatment involves the suppressors and T-helpers; appointment etiotropic, pathogenetic and Activates chemotaxis and phagocytosis; symptomatic remedies. Prescribed pain 3¥©¨°¥•≥ the synthesis of antiherpetic medications before each meal topically on the antibodies; oral mucosa: 5-10% solution anesthesin in Activates the complement system and peach oil, gels with lidocaine, gels with synthesis of endogenous interferon; articaine, etc. After eating, antiseptic treatment Suppresses the replication of viruses the of the oral cavity solution rum furacillin 1: binding to ribosomes affected virus cells and 5000, 3% solution , hydrogen peroxide, 0.1% violation of transcription and translation of solution of rivanola, 0.12% chlorhexidine viral i-RNA. With acute herpetic stomatitis. solution, 0.01% , solution of miramistin, spray "Hexoral". It is also possible to use ©Æ§•≤ï≥ CONCLUSION: means: a strong solution of freshly brewed tea, Those Groprinosin is prescribed to sage broth, etc. Antiviral drugs are prescribed children from the 1st year of life at the rate of tea during the period of rash: 5% ointment 50-100 mg / kg per 3-4 doses (after meals), on with aci- clovir is applied to the lesions 5 times average 5-7 days. For preventive purposes, it is a day. Less effective oxo linen, tebrofen, mean at a dose of 50 mg / kg per day 3 times in florenal, alpisarin ointment. In severe cases week for 3-9 weeks. For the prevention of acyclovir is prescribed internally based on 40 acute herpes it is necessary to protect drive 80 mg / kg / day 5 times a day. strict sanitary control with the use of individual However, clinical experience has been applied masks hygiene products and dishes, cleanliness treatment of antiviral medicinal drugs showed control stats of hands, a ban on kissing a child that none of they are not able to completely and samples of his food, regularly ventilated eliminate remove herpes viruses from the body room installation, etc. and prevent recurrence of herpes infections. Given the constant persistence herpes viruses in the body, their suppressive strong influence on the immune system, in complex therapy of herpetic infection factions include 125 | P a g e NOVATEUR PUBLICATIONS JournalNX- A Multidisciplinary Peer Reviewed Journal ISSN No: 2581 - 4230 VOLUME 6, ISSUE 9, Sep. -2020 REFERENCES: 1) Elizarova V. M., Drobotoko L. N., Strakhova S. Yu. / / Lech. doctor. - 2000. - no. 8.
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