Lobbying Contacts Report 1St January - 30Th June 2016
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The Promise of Human Genome Editing for Rare and Genetic Disease Summary Report of the 2019 FORUM Annual Lecture
The promise of human genome editing for rare and genetic disease Summary report of the 2019 FORUM Annual Lecture The Academy of Medical Sciences The Academy of Medical Sciences is the independent body in the UK representing the diversity of medical science. Our mission is to promote medical science and its translation into benefits for society. The Academy’s elected Fellows are the United Kingdom’s leading medical scientists from hospitals, academia, industry and the public service. We work with them to promote excellence, influence policy to improve health and wealth, nurture the next generation of medical researchers, link academia, industry and the NHS, seize international opportunities and encourage dialogue about the medical sciences. Opinions expressed in this report do not necessarily represent the views of all participants at the event, the Academy of Medical Sciences, or its Fellows. All web references were accessed in February 2020. This work is © Academy of Medical Sciences and is licensed under Creative Commons Attribution 4.0 International. The Academy of Medical Sciences 3 The promise of human genome editing for rare and genetic disease Summary report of the 2019 FORUM Annual Lecture Contents Executive summary .................................................................................................... 4 An introduction to genome editing ................................................................................ 6 Genome editing: moving to the clinic ........................................................................... -
WEEK in BRUSSELS Week Ending Friday 23 January
WEEK IN BRUSSELS Week ending Friday 23 January SMMT strengthens UK auto EU to support studies on dialogue with EU electric vehicle traffic SMMT held its reception in Brussels ‘The UK development automotive industry in Europe’ this week. The reception brought together senior automotive industry The EU’s TEN-T Programme will back a market study executives, UK and EU government officials, MEPs and a pilot on the deployment of electric vehicles and and representatives of the European Commission. A their charging infrastructure along the main highways keynote speech was delivered by Lord Hill, in southern Sweden, Denmark and northern Germany. Commissioner for Financial Stability, Financial The €1 million project aims to contribute to removing Services and Capital Markets Union, in which he barriers for long distance ‘green’ travel across announced the re-launch of the European borders. One of the main barriers to the widespread Commission’s CARS 2020 initiative. Also speaking at use of electric vehicles on European roads is lack of the event were Glenis Willmott MEP, Syed Kamall convenient service stations and their incompatibility MEP and Mike Hawes, SMMT Chief Executive. The with other kinds of vehicles. This project will carry out event presented a key opportunity to demonstrate the feasibility studies on consumer preferences and user strength and importance of the UK automotive acceptance of electric vehicles and the related industry to European colleagues, and to emphasise charging infrastructure, as well as the supporting how having a strong voice in Europe is critical to the consumer services. It will also make a pilot continuing success of the UK automotive sector. -
A Guide to the EU Referendum Debate
‘What country, friends, is this?’ A guide to the EU referendum debate ‘What country, friends, is this?’ A guide to the EU referendum debate Foreword 4 Professor Nick Pearce, Director of the Institute for Policy Research Public attitudes and political 6 discourses on the EU in the Brexit referendum 7 ‘To be or not to be?’ ‘Should I stay or should I go?’ and other clichés: the 2016 UK referendum on EU membership Dr Nicholas Startin, Deputy Head of the Department of Politics, Languages & International Studies 16 The same, but different: Wales and the debate over EU membership Dr David Moon, Lecturer, Department of Politics, Languages & International Studies 21 The EU debate in Northern Ireland Dr Sophie Whiting, Lecturer, Department of Politics, Languages & International Studies 24 Will women decide the outcome of the EU referendum? Dr Susan Milner, Reader, Department of Politics, Languages & International Studies 28 Policy debates 29 Brexit and the City of London: a clear and present danger Professor Chris Martin, Professor of Economics, Department of Economics 33 The economics of the UK outside the Eurozone: what does it mean for the UK if/when Eurozone integration deepens? Implications of Eurozone failures for the UK Dr Bruce Morley, Lecturer in Economics, Department of Economics 38 Security in, secure out: Brexit’s impact on security and defence policy Professor David Galbreath, Professor of International Security, Associate Dean (Research) 42 Migration and EU membership Dr Emma Carmel, Senior Lecturer, Department of Social & Policy Sciences 2 ‘What country, friends, is this?’ A guide to the EU referendum debate 45 Country perspectives 46 Debating the future of Europe is essential, but when will we start? The perspective from France Dr Aurelien Mondon, Senior Lecturer, Department of Politics, Languages & International Studies 52 Germany versus Brexit – the reluctant hegemon is not amused Dr Alim Baluch, Teaching Fellow, Department of Politics, Languages & International Studies 57 The Brexit referendum is not only a British affair. -
BBSRC Annual Report and Accounts 2007-08 HC
ANNUAL REPORT & ACCOUNTS 2007-2008 Biotechnology and Biological Sciences Research Council ANNUAL REPORT & ACCOUNTS 2007-2008 Presented to Parliament by the Secretary of State, and by the Comptroller and Auditor General, in pursuance of Schedule 1, Sections 2 [2] and 3 [3] of the Science and Technology Act 1965. Ordered to be printed by the House of Commons 16 July 2008. HC761 LONDON: The Stationery Office £18.55 Contents PART 1: MANAGEMENT COMMENTARY Chairman’s statement 1 Chief Executive’s report 3 Supporting world class research 6 Key funding data 7 Embedding Systems Biology 11 Major collaborative and multidisciplinary programmes 12 Delivering economic and social benefits 14 Collaborative research with industry 14 Commercialising research outputs 17 Tackling major challenges 20 People, skills, training and knowledge flows 22 Embedding our science in society 26 Opinion gathering and public dialogue 26 Outreach and engagement 28 Engaging young people in science 29 Corporate information 30 2007-2008 Council 30 Boards, Panels and Committees 31 Organisational developments 36 Financial review 39 Remuneration report 42 PART 2: ANNUAL ACCOUNTS Financial statements for the year ended 31 March 2008 45 This Annual Report covers the period from 1 April 2007 to 31 March 2008. BBSRC ANNUAL REPORT & ACCOUNTS BBSRC ANNUAL The Biotechnology and Biological Sciences Research Council (BBSRC), established by Royal Charter in 1994, is the UK’s principal funder of basic and strategic research across the biosciences (www. bbsrc.ac.uk). It is funded primarily by the Science Budget, through the Department for Innovation, Universities and Skills (DIUS). Our mission is to support high-class science and research training, and to promote knowledge transfer in support of bio-based industries and public engagement in bioscience. -
Winter for the Membership of the American Crystallographic Association, P.O
AMERICAN CRYSTALLOGRAPHIC ASSOCIATION NEWSLETTER Number 4 Winter 2004 ACA 2005 Transactions Symposium New Horizons in Structure Based Drug Discovery Table of Contents / President's Column Winter 2004 Table of Contents President's Column Presidentʼs Column ........................................................... 1-2 The fall ACA Council Guest Editoral: .................................................................2-3 meeting took place in early 2004 ACA Election Results ................................................ 4 November. At this time, News from Canada / Position Available .............................. 6 Council made a few deci- sions, based upon input ACA Committee Report / Web Watch ................................ 8 from the membership. First ACA 2004 Chicago .............................................9-29, 38-40 and foremost, many will Workshop Reports ...................................................... 9-12 be pleased to know that a Travel Award Winners / Commercial Exhibitors ...... 14-23 satisfactory venue for the McPherson Fankuchen Address ................................38-40 2006 summer meeting was News of Crystallographers ...........................................30-37 found. The meeting will be Awards: Janssen/Aminoff/Perutz ..............................30-33 held at the Sheraton Waikiki Obituaries: Blow/Alexander/McMurdie .................... 33-37 Hotel in Honolulu, July 22-27, 2005. Council is ACA Summer Schools / 2005 Etter Award ..................42-44 particularly appreciative of Database Update: -
On Faithfulness and Factuality in Abstractive Summarization
On Faithfulness and Factuality in Abstractive Summarization Joshua Maynez∗ Shashi Narayan∗ Bernd Bohnet Ryan McDonald Google Research fjoshuahm,shashinarayan,bohnetbd,[email protected] Abstract understanding how maximum likelihood training and approximate beam-search decoding in these It is well known that the standard likelihood models lead to less human-like text in open-ended training and approximate decoding objectives text generation such as language modeling and in neural text generation models lead to less human-like responses for open-ended tasks story generation (Holtzman et al., 2020; Welleck such as language modeling and story gener- et al., 2020; See et al., 2019). In this paper we ation. In this paper we have analyzed limi- investigate how these models are prone to gener- tations of these models for abstractive docu- ate hallucinated text in conditional text generation, ment summarization and found that these mod- specifically, extreme abstractive document summa- els are highly prone to hallucinate content that rization (Narayan et al., 2018a). is unfaithful to the input document. We con- Document summarization — the task of produc- ducted a large scale human evaluation of sev- eral neural abstractive summarization systems ing a shorter version of a document while preserv- to better understand the types of hallucinations ing its information content (Mani, 2001; Nenkova they produce. Our human annotators found and McKeown, 2011) — requires models to gener- substantial amounts of hallucinated content in ate text that is not only human-like but also faith- all model generated summaries. However, our ful and/or factual given the document. The exam- analysis does show that pretrained models are ple in Figure1 illustrates that the faithfulness and better summarizers not only in terms of raw factuality are yet to be conquered by conditional metrics, i.e., ROUGE, but also in generating text generators. -
The European Conservatives and Reformists in the European Parliament
The European Conservatives and Reformists in the European Parliament Standard Note: SN/IA/6918 Last updated: 16 June 2014 Author: Vaughne Miller Section International Affairs and Defence Section Parties are continuing negotiations to form political groups in the European Parliament (EP) following European elections on 22-25 May 2014. This note looks at the future composition of the European Conservatives and Reformists group (ECR), which was established by UK Conservatives when David Cameron took them out of the centre-right EPP-ED group in 2009. It also considers what the entry of the German right-wing Alternative für Deutschland group into the ECR group might mean for Anglo-German relations. The ECR might become the third largest political group in the EP, although this depends on support for the Liberals and Democrats group. The final number and composition of EP political groups will not be known until after 24 June 2014, which is the deadline for registering groups. For detailed information on the EP election results, see Research paper 14/32, European Parliament Elections 2014, 11 June 2014. This information is provided to Members of Parliament in support of their parliamentary duties and is not intended to address the specific circumstances of any particular individual. It should not be relied upon as being up to date; the law or policies may have changed since it was last updated; and it should not be relied upon as legal or professional advice or as a substitute for it. A suitably qualified professional should be consulted if specific advice or information is required. -
Astex Pharmaceuticals Announces the Appointment of President Harren Jhoti, Phd to the Bioindustry Association Board of Directors
October 10, 2012 Astex Pharmaceuticals Announces the Appointment of President Harren Jhoti, PhD to the BioIndustry Association Board of Directors DUBLIN, Calif., Oct. 10, 2012 (GLOBE NEWSWIRE) -- Astex Pharmaceuticals, Inc. (Nasdaq:ASTX), a pharmaceutical company dedicated to the discovery and development of novel small molecule therapeutics, announced that Harren Jhoti, PhD, president and director of Astex Pharmaceuticals, was appointed to the BioIndustry Association (BIA) Board of Directors. About Harren Jhoti, PhD Dr. Harren Jhoti has served as Astex Pharmaceuticals president and member of the Board of Directors since the company's formation in July 2011. He co-founded Astex Therapeutics in 1999 and was chief scientific officer until November 2007 when he was appointed chief executive. Dr. Jhoti was awarded the Prous Institute-Overton and Meyer Award for New Technologies in Drug Discovery by the European Federation for Medicinal Chemistry in 2012 and was also named by the Royal Society of Chemistry as "Chemistry World Entrepreneur of the Year" for 2007. He has published widely including in leading journals such as Nature and Science and has also been featured in TIME magazine after being named by the World Economic Forum a Technology Pioneer in 2005. Dr. Jhoti served as a non-executive director of Iconix Inc. Before starting up Astex Therapeutics in 1999, he was head of Structural Biology and Bioinformatics at GlaxoWellcome in the United Kingdom (1991-1999). Prior to Glaxo, Dr. Jhoti was a post-doctoral scientist at Oxford University. He received a BSc (Hons) in Biochemistry in 1985 and a PhD in Protein Crystallography from the University of London in 1989. -
Exclusive Interview with Dr
State: A Last Resort for People Exclusive interview with Dr. Syed Kamall Conducted by Bardia Garshasbi in London– July 2014 Syed Kamall is a phenomenon in his own right. He comes from an ordinary Guyanese family who migrated to London in mid-1950s. His father was a bus driver, and now at the age of 47, he is the leader of the Britain’s Conservative Party in the European Parliament, representing the people of London in that parliament since 2005, when he was only 38! Having degrees from some of the world’s most prestigious universities (London School of Economics and City University London) Dr. Kamall also chairs the European Conservatives and Reformist Group, the EU Parliament’s third largest group with 70 MEPs who are campaigning for urgent reform of the EU and of whom Syed is, as he proudly puts it, “the first group leader from an ethnic minority and the first Muslim ever”. Dr. Kamall is one of the few successful and highly educated politicians in Europe who does not come from an elite background or rich family. His path to success has been uphill and demanding. He has firsthand knowledge of the challenges low-income families are facing in their daily lives. That is why the relief of poverty has always been a top priority for him. He works tirelessly to find ways to tackle poverty by educating the young and by creating incentives and equal opportunities for hard- working people. His constituents in London and his peers in both Britain and Europe know him for his intelligence, decency, and eloquence. -
Anew Drug Design Strategy in the Liht of Molecular Hybridization Concept
www.ijcrt.org © 2020 IJCRT | Volume 8, Issue 12 December 2020 | ISSN: 2320-2882 “Drug Design strategy and chemical process maximization in the light of Molecular Hybridization Concept.” Subhasis Basu, Ph D Registration No: VB 1198 of 2018-2019. Department Of Chemistry, Visva-Bharati University A Draft Thesis is submitted for the partial fulfilment of PhD in Chemistry Thesis/Degree proceeding. DECLARATION I Certify that a. The Work contained in this thesis is original and has been done by me under the guidance of my supervisor. b. The work has not been submitted to any other Institute for any degree or diploma. c. I have followed the guidelines provided by the Institute in preparing the thesis. d. I have conformed to the norms and guidelines given in the Ethical Code of Conduct of the Institute. e. Whenever I have used materials (data, theoretical analysis, figures and text) from other sources, I have given due credit to them by citing them in the text of the thesis and giving their details in the references. Further, I have taken permission from the copyright owners of the sources, whenever necessary. IJCRT2012039 International Journal of Creative Research Thoughts (IJCRT) www.ijcrt.org 284 www.ijcrt.org © 2020 IJCRT | Volume 8, Issue 12 December 2020 | ISSN: 2320-2882 f. Whenever I have quoted written materials from other sources I have put them under quotation marks and given due credit to the sources by citing them and giving required details in the references. (Subhasis Basu) ACKNOWLEDGEMENT This preface is to extend an appreciation to all those individuals who with their generous co- operation guided us in every aspect to make this design and drawing successful. -
Speakers 2020
Institute of Economic Affairs SPEAKERS 2020 [email protected] iea.org.uk AdamAdam BarthaBartha Adam isis the the Director Director of ofEPICENTER, EPICENTER, a network a network of nine of leadingnine leading free-market free-market think tanks think from tanks across fromEurope.from across He is Europe.responsible He for is responsiblethe co-ordination for the and coordinationco-operation ofand the cooperation network and offor the organising networkthe private and and for public organising events programmethe private inand Brussels. public Adam events gives programme regular talks in Brussels.on topics ranging Adamfrom the gives rule ofregular law, authoritarian talks on topics populism, ranging free from market the reforms, rule of and law, the authoritarian political affairs of the CEE populism,region. Adam free was market previously reforms, European and Outreachthe political Manager affairs at EPICENTERof the CEE and region. a Koch Adam Summer was Fellow previouslyin the Publications European Department Outreach of theManager Independent at EPICENTER Institute in and California. a Koch He Summer also has Fellow experience in in thedomestic Publi-cations party politics Department in Germany of and the Hungary. Independent Adam hasInstitute a BA (Hons) in California. in Politics He and also International has experienceRelations from in thedomestic University party of Sheffield politics inand Germany an MSc in and Political Hungary. Theory Adam from hasthe Londona BA (Hons) School of inEconomics.in PoliticsPolitics and andAdam InternationalInternational is fluent in RelationsEnglish,Relations German fromfrom thetheand UniversityUniversityHungarian. ofof SheffieldSheffield andand anan MScMSc inin PoliticalPossible topics Theory include from EU the integration, London School Populism, of Economics.Rule of Law, Central-andAdam is fluent Eastern in English,European Political Germanand Economic and Hungarian.Affairs. -
Dr Syed Kamall MEP Hosts Virtual Currencies and Blockchain
Dr Syed Kamall MEP hosts virtual currencies and blockchain exhibition in European Parliament organised by The Cobden Centre Submitted by: Jessica King PR Tuesday, 19 April 2016 As a group leader within the European Parliament Dr Syed Kamall MEP, the Chairman of the European Conservatives and Reformists Group, has the opportunity to host an exhibition within the Parliament during his 5 year term. He has chosen to have the exhibition on virtual currencies and blockchain technology, an event which is being organised by The Cobden Centre in association with EDCAB. Attendees will include the World Bank, IMF, OECD, Bank for International Settlements, Europol and the United Nations (UNICRI). It will be the first time these institutions have come together for a blockchain event. They will be joined by academics, startups, established companies and thinkers. "I am delighted to be hosting this exhibition on blockchain and virtual currencies in the European Parliament. The technology offers some very exciting opportunities but as legislators internationally, we must also make sure that consumers have trust in it,” commented Dr Syed Kamall MEP. “This is a unique opportunity to have some of the world’s top economic institutions here to discuss the issues we need to consider in the European Parliament." Virtual currencies are now being looked at by central banks, treasuries and financial institutions. The technology behind them, known as blockchain technology or distributed ledger technology, is of particular interest. This allows assets to be transferred peer to peer in much the same way that bitcoins can be transferred peer to peer. In theory it could mean that large sections of the economy could trade without centralised intermediaries like banks.