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Protecting Yourself with Repellents

Originally developed by Dr. Sonja L. Swiger and Molly Keck with Mike Merchant What is a repellent?

Anything that repels, or disrupts the normal host seeking behavior of, a pest. Repellents are a kind of

 Any substance or mixture of substances used to prevent, destroy, repel pest or reduce the damage caused by pests  Subject to same label requirements as all

Learn the label

 Look for the EPA registration and Establishment numbers on the repellent product label. ◉ This registration number means the company provided EPA with technical information on the effectiveness of the product against mosquitoes and/or .  Some repellents may state that they are exempt from federal labeling laws under a Section 25(b) exemption Learn the label

 Read all the directions for use  Label instructions are legal requirements, not suggestions

N,N-diethyl-m-toluamide (DEET)

 U.S. military discovered repellency of DEET in 1953  Broad spectrum repellent effective against all mosquitoes, some and ticks  Est. 78 million people in U.S. use DEET safely US troops receiving repellents at the end of each year WWII. and other insect born diseases were a major source of casualties in the Pacific theater, leading to ground breaking research on repellents. DEET

 Principal, most effective repellent available today  The standard against which all other repellents are compared  Most thoroughly studied and tested with protection documented up to 6-8 hours Health concerns with DEET?

 Reports linking it to seizures, encephalopathy, neurotoxicity, especially in children  Very small number of cases, most of which associated with excessive or inappropriate use  1998 EPA re-assessment of DEET concluded that if label directions are followed, repellents with DEET do not pose a health concern to the general population, including children and pregnant women.

The Four Ds are changing

◉ Drain standing water ◉ Stay indoors during Dawn and Dusk ◉ Dress in long sleeves and pants ◉ DEET ◉ DEET no longer the only acceptable product for repellency Commercial Insect Repellents

 EPA Registered Repellents:  CDC Approved Products: ◉ DEET ◉ DEET ◉ Picaridin ◉ Picaradin ◉ IR3535 ◉ IR3535 ◉ Citronella ◉ Oil of Lemon Eucalyptus ◉ 2-undecanone ◉ Oil of Lemon Eucalyptus ◉ Oil

CDC recommendations:

 Products containing these active ingredients typically provide reasonably long-lasting protection: ◉ DEET ◉ Picaridin ◉ Oil of Lemon Eucalyptus* or PMD (Chemical Name: para- Menthane-3,8-diol) the synthesized version of oil of lemon eucalyptus ◉ IR3535 (Chemical Name: 3-[N-Butyl-N-acetyl]-aminopropionic acid, ethyl ester) Picaridin (2-(2-hydroxyethyl)-1-piperidinecarboxylic acid 1-methylpropyl ester; KBR3023)

 Registered by US EPA 2003  High level of control comparable in many studies to DEET  Low odor, not oily  EPA lists as 3-8 hours repellency for different concentrations Oil of Lemon Eucalyptus Para-menthane-3,8-diol (PMD)

 Derived from leaves of eucalyptus plant  Similar smell and cooling to  EPA lists protection time at 6 hrs for most products containing 30-40% active ingredient IR3535 3-[N-Butyl-N-acetyl]-aminopropionic acid, ethyl ester

 Used in Europe for 20 years prior to US registration in 1999  Relatively short complete protection time, less than one-hour in some studies  Among recommended products by CDC, for those needing shorter protection times than DEET BioUD 2 - undecanone

 Registered 2007 by EPA  Originally derived from wild tomatoes  North Carolina State University 2008 lab studies ◉ Arm cage studies compared favorably to DEET for  Not yet on recommended list from CDC Citronella

 Not included on CDC recommended list, but shows some repellency for shorter times (generally less than one hour)  Commercial product examples ◉ Buzz Away ◉ Citronella, cedarwood, eucalyptus, lemongrass ◉ Alleged USDA 8 hour protection ◉ 1997, Oregon State Study – slight repellency at 0.5 hours, none after ◉ Green Ban ◉ Citronella, cedarwood, eucalyptus, lavender, sassfras, …. ◉ No repellency

Off! Clip-On Mosquito Repellent

 Releases vaporized form of (pyrethroid) and expels via small fan. To be clipped on a belt. ◉ Spatial repellency ◉ Mortality of mosquitoes  Wind, personal movement may reduce effectiveness  Limited studies ◉ 70% & 79% protection, Aedes albopictus, A. taeniorhychus (Xue et al, 2012)

Repellents for clothing  Certain products containing are recommended ◉ on clothing ◉ shoes ◉ bed nets ◉ camping gear  Permethrin products should not be applied directly to skin  Repellent treated clothing good for 30-40 washings Choosing an Insect Repellent: How Do I Know Which Repellent is Right?

 Key points to remember when selecting an insect repellent include: ◉ from which you want protection ◉ Length of time you need protection ◉ Active ingredient and percent

Repellents and Children

◉ DEET products should not be used on children less than 2 months old ◉ American Academy of Pediatrics recommends using products containing no more than 30% DEET on children ◉ Oil of lemon eucalyptus products should not be used on children under the age of three. ◉ The CDC does not recommend use of products that combine a sunscreen with an insect repellent because the sunscreen has to be reapplied more often than the repellent.

Repellents and Children

 Common label precautions ◉ "Do not allow children to handle this product, and do not apply to children’s hands. When using on children, apply to your own hands and then put it on the child. ◉ “After returning indoors, wash your child’s treated skin and clothes with soap and water or bathe."

Repellents and Children

 Additional Information About Safe Use of Insect Repellents ◉ Insect Repellent Use and Safety - Centers for Disease Control and Prevention (CDC) ◉ Using Insect Repellents on Children- Centers for Disease Control and Prevention (CDC) ◉ Traveler's Health: Mosquito and Protection - Centers for Disease Control and Prevention (CDC) ◉ Safety Tips on Using Personal Insect Repellents - Health Canada ◉ Repellents and Children - American Academy of Pediatrics ◉ DEET General Fact Sheet – NPIC

Insect Repellent calculators

http://cfpub.epa.gov/oppref/insect Insect repellent calculators

National Pesticide Information Center

http://pi.ace.orst.edu/repellents/ Home remedies that don’t work Consumer Report 2012

http://www.consumerreports.org/cro/2012/08/best-insect-repellents/index.htm