RPS6KA1 monoclonal antibody, Summary: This gene encodes a member of the clone 8C12 RSK (ribosomal S6 ) family of serine/threonine . This kinase contains 2 nonidentical kinase Catalog Number: MAB0792 catalytic domains and phosphorylates various substrates, including members of the mitogen-activated Regulatory Status: For research use only (RUO) kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and Product Description: Mouse monoclonal antibody differentiation. Alternate transcriptional splice variants, raised against partial recombinant RPS6KA1. encoding different isoforms, have been characterized. [provided by RefSeq] Clone Name: 8C12 References: Immunogen: Recombinant His fusion protein 1. Phosphorylation of p90 (RSK) corresponding to amino acids 418-735 of human regulates extracellular signal-regulated kinase docking RPS6KA1. and RSK activity. Roux PP, Richards SA, Blenis J. Mol Cell Biol. 2003 Jul;23(14):4796-804. Host: Mouse 2. Role and regulation of 90 kDa ribosomal S6 kinase (RSK) in . Frodin M, Gammeltoft S. Reactivity: Human Mol Cell Endocrinol. 1999 May 25;151(1-2):65-77. Applications: ELISA, IP, WB-Ce 3. Evidence for two catalytically active kinase domains in (See our web site product page for detailed applications pp90rsk. Fisher TL, Blenis J. Mol Cell Biol. 1996 information) Mar;16(3):1212-9.

Protocols: See our web site at http://www.abnova.com/support/protocols.asp or product page for detailed protocols

Form: Liquid

Purification: Ammonium sulfate precipitation

Isotype: IgG1, kappa

Recommend Usage: Western Blot (1:1800) Immunoprecipitation (0.5 ul) The optimal working dilution should be determined by the end user.

Storage Buffer: In HEPES, 150 mM NaCl (50% glycerol, 0.01% BSA, 0.03% sodium azide)

Storage Instruction: Store at -20°C. Aliquot to avoid repeated freezing and thawing.

Entrez GeneID: 6195

Gene Symbol: RPS6KA1

Gene Alias: HU-1, MAPKAPK1A, RSK, RSK1

Page 1/1

Powered by TCPDF (www.tcpdf.org)