Getting Off Right: a Safety Manual For
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An Intramuscular Injection Is an Injection Given Directly Into The
Depo Lupron and Testosterone are both given by intramuscular injection. The following is a guideline on their administration. Eileen Durham, RN, NP Version 12 Jan 2010 Description Intramuscular (IM) injections are given directly into the central area of selected muscles. There are a number of sites that are suitable for IM injections; there are three sites that are most commonly used in this procedure described below. The volume of viscosity of the medication to be injected determines the site that should be used. IM injections cause stretching of the muscle fiber so the larger the muscle used the less discomfort. Intramuscular Injection Sites Depo Lupron Depo Lupron 3 month preparation should only be injected into the Gluteus medius due to the viscosity and volume of the medication approx. 1.5 – 2 cc. Depo Lupron 1 month preparation can be injection into the vastus lateralis or the gluteus medius. Testosterone Testosterone administered to adolescents and adults can be injected into any of the sites listed below, as long as the volume is 1 cc or less. For a volume of 1.5 use the vastus lateralis or Gluteus medius, if the volume is 2 cc you must you the largest muscle the Gluteus medius. If the volume is greater then 2 cc you must divide the dose and give 2 injections as the maximum volume in the Gluteal muscle is 2 cc. Testosterone administered to infants and toddlers use only the anteriolateral aspect of the thigh. Deltoid muscle The deltoid muscle located laterally on the upper arm can be used for intramuscular injections. -
Intravenous Therapy Procedure Manual
INTRAVENOUS THERAPY PROCEDURE MANUAL - 1 - LETTER OF ACCEPTANCE __________________________________________ hereby approves (Facility) the attached Reference Manual as of _____________________. (Date) The Intravenous Therapy Procedure Manual will be reviewed at least annually or more often when deemed appropriate. Revisions will be reviewed as they occur. Current copies of the Intravenous Therapy Procedure Manual shall be maintained at each appropriate nursing station. I have reviewed this manual and agree to its approval. __________________________ (Administrator) __________________________ (Director of Nursing) __________________________ (Medical Director) - 2 - TABLE OF CONTENTS TABLE OF CONTENTS INTRODUCTION A. Purpose 1 B. Local Standard of Practice 1 RESPONSIBILITIES A. Responsibilities: M Chest Pharmacy 1 B. Responsibilities: Administrator 1 C. Responsibilities: Director of Nursing Services (DON/DNS) 1 D. Skills Validation 2 AMENDMENTS GUIDELINES A. Resident Candidacy for IV Therapy 1 B. Excluded IV Medications and Therapies 1 C. Processing the IV Order 1 D. IV Solutions/Medications: Storage 2 E. IV Solutions/Medications: Handling 3 F. IV Solutions and Supplies: Destroying and Returning 4 G. IV Tubing 5 H. Peripheral IV Catheters and Needles 6 I. Central Venous Devices 7 J. Documentation and Monitoring 8 K. IV Medication Administration Times 9 L. Emergency IV Supplies 10 I TABLE OF CONTENTS PROTOCOLS A. IV Antibiotic 1 1. Purpose 2. Guidelines 3. Nursing Responsibilities B. IV Push 2 1. Purpose 2. Guidelines C. Anaphylaxis Allergic Reaction 4 1. Purpose 2. Guidelines 3. Nursing Responsibilities and Interventions 4. Signs and Symptoms of Anaphylaxis 5. Drugs Used to Treat Anaphylaxis 6. Physician Protocol PRACTICE GUIDELINES A. Purpose 1 B. Personnel 1 C. Competencies 1 D. -
Wesst Arceen Named As the Sole Contingent Beneficiary
Texas High School Mock Trial Competition 2017 Case Materials State of Texoma v. Houston Whit Cause No. 16-908 § STATE OF TEXOMA § IN THE CRIMINAL COURT § v. § § OF HOUSTON WHIT, § LANDRY COUNTY, TEXOMA § Defendant § § § § CASE MATERIALS PREPARED BY: Stephen W. Gwinn, Esq. Chair, Mock Trial Committee Fred Moss, Esq. Mock Trial Committee Sarah Flournoy, Esq. Co-Vice Chair, Mock Trial Committee Tasha James, Esq. Co-Vice Chair, Mock Trial Committee Brad Johnson, Esq. Co-Vice Chair, Mock Trial Committee James D. Blume, Esq. Spencer Bryson, Esq. Jacquelyn Clark, Esq. Jaclyn Kerbow, Esq. Cari LaSala, Esq. Scott Seelhoff, Esq. Stephen Stapleton, Esq. Cover Design, Cari LaSala, Esq. COPYRIGHT 2016-2017 TEXAS HIGH SCHOOL MOCK TRIAL COMPETITION. ALL RIGHTS RESERVED. Cause No. 16-908 § STATE OF TEXOMA § § IN THE CRIMINAL DISTRICT COURT v. § § OF HOUSTON WHIT, § § LANDRY COUNTY, TEXOMA Defendant. § § STIPULATIONS OF THE PARTIES The parties agree and stipulate as to the following: I. This is a criminal trial that will be tried before a jury. The Prosecution is being made by and in the name of the State of Texoma. Houston Whit is the Defendant. The Defendant has been charged by information with the criminal offense of murder. This will be a bifurcated trial. The parties will only try the issue of guilt or innocence. Should the Defendant be found guilty, there will be a separate trial on the issue of punishment at some future date. An appropriate punishment or the range of punishment is, therefore, not at issue in this trial and is not to be argued. Each person who is a witness has been properly advised of their constitutional rights. -
HIV and Substance Use October 2016
HIV and Substance Use October 2016 Fast Facts • Alcohol and other drugs can affect a person’s judgment and increase risk of getting or transmitting HIV. • In people living with HIV, substance use can worsen the overall consequences of HIV. • Social and structural factors make it difficult to prevent HIV among people who use substances. Substance use disorders, which are problematic patterns of using alcohol or another substance, such as crack cocaine, methamphetamine (“meth”), amyl nitrite (“poppers”), prescription opioids, and heroin, are closely associated with HIV and other sexually transmitted diseases. Injection drug use (IDU) can be a direct route of HIV transmission if people share needles, syringes, or other injection materials that are contaminated with HIV. However, drinking alcohol and ingesting, smoking, or inhaling drugs are also associated with increased risk for HIV. These substances alter judgment, which can lead to risky sexual behaviors (e.g., having sex without a condom, having multiple partners) that can make people more likely to get and transmit HIV. In people living with HIV, substance use can hasten disease progression, affect adherence to antiretroviral therapy (HIV medicine), and worsen the overall consequences of HIV. Commonly Used Substances and HIV Risk • Alcohol. Excessive alcohol consumption, notably binge drinking, can be an important risk factor for HIV because it is linked to risky sexual behaviors and, among people living with HIV, can hurt treatment outcomes. • Opioids. Opioids, a class of drugs that reduce pain, include both prescription drugs and heroin. They are associated with HIV risk behaviors such as needle sharing when injected and risky sex, and have been linked to a recent HIV outbreak. -
Injection Technique 1: Administering Drugs Via the Intramuscular Route
Copyright EMAP Publishing 2018 This article is not for distribution except for journal club use Clinical Practice Keywords Intramuscular injection/ Medicine administration/Absorption Practical procedures This article has been Injection technique double-blind peer reviewed Injection technique 1: administering drugs via the intramuscular route rugs administered by the intra- concerns that nurses are still performing Author Eileen Shepherd is clinical editor muscular (IM) route are depos- outdated and ritualistic practice relating to at Nursing Times. ited into vascular muscle site selection, aspirating back on the syringe Dtissue, which allows for rapid (Greenway, 2014) and skin cleansing. Abstract The intramuscular route allows absorption into the circulation (Dough- for rapid absorption of drugs into the erty and Lister, 2015; Ogston-Tuck, 2014). Site selection circulation. Using the correct injection Complications of poorly performed IM Four muscle sites are recommended for IM technique and selecting the correct site injection include: administration: will minimise the risk of complications. l Pain – strategies to reduce this are l Vastus lateris; outlined in Box 1; l Rectus femoris Citation Shepherd E (2018) Injection l Bleeding; l Deltoid; technique 1: administering drugs via l Abscess formation; l Ventrogluteal (Fig 1, Table 1). the intramuscular route. Nursing Times l Cellulitis; Traditionally the dorsogluteal (DG) [online]; 114: 8, 23-25. l Muscle fibrosis; muscle was used for IM injections but this l Injuries to nerves and blood vessels muscle is in close proximity to a major (Small, 2004); blood vessel and nerves, with sciatic nerve l Inadvertent intravenous (IV) access. injury a recognised complication (Small, These complications can be avoided if 2004). -
22428 Moxifloxacin Statisical PREA
U.S. Department of Health and Human Services Food and Drug Administration Center for Drug Evaluation and Research Office of Translational Science Office of Biostatistics S TATISTICAL R EVIEW AND E VALUATION CLINICAL STUDIES NDA/Serial Number: 22,428 Drug Name: Moxifloxacin AF (moxifloxacin hydrochloride ophthalmic solution) 0.5% Indication(s): Treatment of bacterial conjunctivitis Applicant: Alcon Pharmaceuticals, Ltd. Date(s): Letter date:21 May 2010; Filing date: 18 June, 2010; PDUFA goal date: 19 November 2010 Review Priority: Priority Biometrics Division: Anti-infective and Ophthalmology Products Statistical Reviewer: Mark. A. Gamalo, Ph.D. Concurring Reviewers: Yan Wang, Ph.D. Medical Division: Anti-infective and Ophthalmology Products Clinical Reviewer: Lucious Lim, M.D. Project Manager: Lori Gorski Keywords: superiority, Moxifloxacin hydrochloride ophthalmic solution, bacterial conjunctivitis, bulbar conjunctival injection, conjunctival discharge/exudate TABLE OF CONTENTS TABLE OF CONTENTS................................................................................................................ 2 LIST OF TABLES.......................................................................................................................... 3 1. EXECUTIVE SUMMARY ...................................................................................................... 4 1. 1 Conclusions and Recommendations..................................................................................... 4 1. 2 Brief Overview of Clinical Studies ..................................................................................... -
Self-Administering a Vitamin B12 Injection
Self-administering a Vitamin B12 injection This is usually given as an intramuscular injection, every 2-3 months. Alternatives to an intramuscular injection are: Oral Vitamin B12 at a dose of at least 1000mcg per day. • Available as tablets or a spray. They can be bought over the counter and available at most health food stores and pharmacies. • Oral Vitamin B12 is not recommended if: - If you have a bowel condition such as inflammatory bowel disease, Coeliac disease, small bowel overgrowth, bile acid malabsorption and short bowel (you will require injections) - You require an initial loading of B12 (soon after diagnosis) It is important to monitor your symptoms if you change to oral B12. If symptoms return, then the oral/sublingual dose can be increased to 2000mcg or you may need to consider starting back on injections. https://www.hollandandbarrett.com/shop/product/betteryou-pure-energy-b12-boost-oral-spray-60099160?skuid=099160 https://www.hollandandbarrett.com/search?query=%20Vitamin%20B12%20Tablets&utm_medium=cpc&utm_source=google&isSearch=true# gclid=EAIaIQobChMIh5nLgOH26AIVxLTtCh0JIA_GEAAYASAAEgJL-fD_BwE&gclsrc=aw.ds Subcutaneous (SC) injection; this is off-licence but still effective. It is considered an easier method of administration. It is how insulin and blood thinning medication are usually self-administered. Equipment needed to self-inject - Prescribed medicine - 1 syringe (2 ml) - 2 needles (1 for drawing up the drug and 1 for administration – you can use the same size needle for both). o For an IM injection; the needle gauge should be 19-25. The needle length is 1- 1 ½ inches (up to 3 inches for larger adults) o For a SC injection; the needle gauge should be 25-27. -
Advisory Council on the Misuse of Drugs
ACMD Advisory Council on the Misuse of Drugs Chair: Dr Owen Bowden-Jones Secretary: Zahi Sulaiman 1st Floor (NE), Peel Building 2 Marsham Street London SW1P 4DF Tel: 020 7035 1121 [email protected] Sarah Newton MP Minister for Vulnerability, Safeguarding and Countering Extremism Home Office 2 Marsham Street London SW1P 4DF 10 March 2017 Dear Minister, RE: Further advice on methylphenidate-related NPS In February 2016, my predecessor Professor Les Iversen wrote to the then minister for Preventing Abuse, Exploitation and Crime, requesting that the Temporary Class Drug Order (TCDO) on seven methylphenidate-related Novel Psychoactive Substances be re-laid for a further 12 months. This TCDO was re-laid until June 2017, to allow the Advisory Council on the Misuse of Drugs (ACMD) more time to collect the evidence required to provide further advice for full control under the Misuse of Drugs Act 1971. The ACMD believes that the TCDO has been effective in reducing the prevalence of these substances and that the TCDO level of control was proportionate in the interim. I am now pleased to present to you the ACMD’s further advice on this matter in the enclosed report. The ACMD’s recommendation for full control applies to the seven substances currently controlled under the TCDO and extends to an additional five closely-related substances. These five similar substances have subsequently appeared on markets following the TCDO and are included in this advice due to their potential for similar harms. Recommendation The ACMD recommends that the -
Needle Sharing Among Intravenous Drug Abusers: National and International Perspectives
Needle Sharing Among Intravenous Drug Abusers: National and International Perspectives U. S. DEPARTMENT OF HEALTH AND HUMAN SERVICES • Public Health Service • Alcohol, Drug Abuse, and Mental Health Administration Needle Sharing Among Intravenous Drug Abusers: National and International Perspectives Editors: Robert J. Battjes, D.S.W. Roy W. Pickens, Ph.D. Division of Clinical Research National Institute on Drug Abuse NIDA Research Monograph 80 1988 U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES Public Health Service Alcohol, Drug Abuse, and Mental Health Administration National Institute on Drug Abuse 5600 Fishers Lane Rockville, MD 20857 For sale by the Superintendent of Documents, U.S. Government Printing Office Washington, DC 20402 NIDA Research Monographs are prepared by the research divisions of the National Institute on Drug Abuse and published by its Office of Science. The primary objective of the series is to provide critical reviews of research problem areas and techniques, the content of state-of-the-art conferences, and integrative research reviews. Its dual publication emphasis is rapid and targeted dissemination to the scientific and professional community. Editorial Advisors MARTIN W. ADLER, Ph.D. MARY L. JACOBSON Temple University School of Medrcrne National Federation of Parents for Philadelphia. Pennsylvania Drug-Free Youth Omaha, Nebraska SYDNEY ARCHER, Ph.D. Rensselaer Polytechnic Institute Troy, New York REESE T. JONES, M.D. Langley Porter Neuropsychiatric lnstitute RICHARD E. BELLEVILLE. Ph.D. San Francisco, California NB Associates, Health Sciences RockviIle, Maryland DENISE KANDEL, Ph.D. KARST J. BESTEMAN College of Physicians and Surgeons of Alcohol and Drug Problems Association Columbia University of North America New York, New York Washington, D. -
Treatment of Alzheimer's Disease and Blood–Brain Barrier Drug Delivery
pharmaceuticals Review Treatment of Alzheimer’s Disease and Blood–Brain Barrier Drug Delivery William M. Pardridge Department of Medicine, University of California, Los Angeles, CA 90024, USA; [email protected] Received: 24 October 2020; Accepted: 13 November 2020; Published: 16 November 2020 Abstract: Despite the enormity of the societal and health burdens caused by Alzheimer’s disease (AD), there have been no FDA approvals for new therapeutics for AD since 2003. This profound lack of progress in treatment of AD is due to dual problems, both related to the blood–brain barrier (BBB). First, 98% of small molecule drugs do not cross the BBB, and ~100% of biologic drugs do not cross the BBB, so BBB drug delivery technology is needed in AD drug development. Second, the pharmaceutical industry has not developed BBB drug delivery technology, which would enable industry to invent new therapeutics for AD that actually penetrate into brain parenchyma from blood. In 2020, less than 1% of all AD drug development projects use a BBB drug delivery technology. The pathogenesis of AD involves chronic neuro-inflammation, the progressive deposition of insoluble amyloid-beta or tau aggregates, and neural degeneration. New drugs that both attack these multiple sites in AD, and that have been coupled with BBB drug delivery technology, can lead to new and effective treatments of this serious disorder. Keywords: blood–brain barrier; brain drug delivery; drug targeting; endothelium; Alzheimer’s disease; therapeutic antibodies; neurotrophins; TNF inhibitors 1. Introduction Alzheimer’s Disease (AD) afflicts over 50 million people world-wide, and this health burden costs over 1% of global GDP [1]. -
Epidemics of HIV, HCV and Syphilis Infection Among Synthetic Drugs
www.nature.com/scientificreports OPEN Epidemics of HIV, HCV and syphilis infection among synthetic drugs only users, heroin-only users and Received: 7 November 2017 Accepted: 28 March 2018 poly-drug users in Southwest China Published: xx xx xxxx Shu Su1, Limin Mao 2, Jinxian Zhao3, Liang Chen3, Jun Jing4, Feng Cheng4 & Lei Zhang 1,4,5 The number of poly-drug users who mix use heroin and synthetic drugs (SD) is increasing worldwide. The objective of this study is to measure the risk factors for being infected with hepatitis C (HCV), human immunodefciency virus (HIV) and syphilis among SD-only users, heroin-only users and poly- drug users. A cross-sectional study was conducted in 2015 from a national HIV surveillance site in Southwest China, 447 poly-drug, 526 SD-only and 318 heroin-only users were recruited. Poly-drug users have higher drug-use frequency, higher rates of drug-sharing and unsafe sexual acts than other users (p < 0.05). About a third (36.7%) of poly-drug users experienced sexual arousal due to drug efects, which is higher than the rate among other drug users. Poly-drug users had the highest prevalence of HIV (10.5%) and syphilis (3.6%), but heroin-only users had the highest prevalence of HCV (66.0%) (all p < 0.05) among three groups. Logistic regression shows among poly-drug users, having sex following drug consumption and using drugs ≥1/day were the major risk factors for both HIV (Adjusted odds ratio (AOR) = 2.4, 95% CI [1.8–3.4]; 2.3, [1.6–3.1]) and syphilis infection (AOR = 4.1, [2.1–6.9]; 3.9, [1.8–5.4]). -
Karaoke Book
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