ATP2A3 Antibody Cat. No.: 26-148

ATP2A3 Antibody

Antibody used in WB on Jurkat cells at 0.2-1 ug/ml.

Specifications

HOST SPECIES: Rabbit

SPECIES REACTIVITY: Human

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region IMMUNOGEN: of human ATP2A3.

TESTED APPLICATIONS: ELISA, WB

ATP2A3 antibody can be used for detection of ATP2A3 by ELISA at 1:312500. ATP2A3 APPLICATIONS: antibody can be used for detection of ATP2A3 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

POSITIVE CONTROL: 1) Cat. No. 1205 - Jurkat Cell Lysate

PREDICTED MOLECULAR 109 kDa WEIGHT:

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PURIFICATION: Antibody is purified by peptide affinity chromatography method.

CLONALITY: Polyclonal

CONJUGATE: Unconjugated

PHYSICAL STATE: Liquid

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% BUFFER: sucrose.

CONCENTRATION: batch dependent

For short periods of storage (days) store at 4˚C. For longer periods of storage, store STORAGE CONDITIONS: ATP2A3 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Additional Info

OFFICIAL SYMBOL: ATP2A3

ALTERNATE NAMES: ATP2A3, SERCA3

ACCESSION NO.: NP_005164

PROTEIN GI NO.: 28373103

GENE ID: 489

USER NOTE: Optimal dilutions for each application to be determined by the researcher.

Background and References

ATP2A3 is one of the SERCA Ca (2+)-, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the to the lumen, and is involved in calcium sequestration associated with muscular excitation and contraction.This encodes one of the SERCA Ca (2+)-ATPases, which are BACKGROUND: intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in calcium sequestration associated with muscular excitation and contraction. Alternative splicing results in multiple transcript variants encoding different isoforms.

REFERENCES: 1) Korosec, B., (2008) Cancer Genet. Cytogenet. 181 (2), 112-118.

ANTIBODIES FOR RESEARCH USE ONLY.

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