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TRINITY COLLEGE Cambridge Trinity College Cambridge College Trinity Annual Record Annual
2016 TRINITY COLLEGE cambridge trinity college cambridge annual record annual record 2016 Trinity College Cambridge Annual Record 2015–2016 Trinity College Cambridge CB2 1TQ Telephone: 01223 338400 e-mail: [email protected] website: www.trin.cam.ac.uk Contents 5 Editorial 11 Commemoration 12 Chapel Address 15 The Health of the College 18 The Master’s Response on Behalf of the College 25 Alumni Relations & Development 26 Alumni Relations and Associations 37 Dining Privileges 38 Annual Gatherings 39 Alumni Achievements CONTENTS 44 Donations to the College Library 47 College Activities 48 First & Third Trinity Boat Club 53 Field Clubs 71 Students’ Union and Societies 80 College Choir 83 Features 84 Hermes 86 Inside a Pirate’s Cookbook 93 “… Through a Glass Darkly…” 102 Robert Smith, John Harrison, and a College Clock 109 ‘We need to talk about Erskine’ 117 My time as advisor to the BBC’s War and Peace TRINITY ANNUAL RECORD 2016 | 3 123 Fellows, Staff, and Students 124 The Master and Fellows 139 Appointments and Distinctions 141 In Memoriam 155 A Ninetieth Birthday Speech 158 An Eightieth Birthday Speech 167 College Notes 181 The Register 182 In Memoriam 186 Addresses wanted CONTENTS TRINITY ANNUAL RECORD 2016 | 4 Editorial It is with some trepidation that I step into Boyd Hilton’s shoes and take on the editorship of this journal. He managed the transition to ‘glossy’ with flair and panache. As historian of the College and sometime holder of many of its working offices, he also brought a knowledge of its past and an understanding of its mysteries that I am unable to match. -
Autism and MMR Vaccine Study an 'Elaborate Fraud,' Charges BMJ Deborah Brauser Authors and Disclosures
Autism and MMR Vaccine Study an 'Elaborate Fraud,' Charges BMJ Deborah Brauser Authors and Disclosures January 6, 2011 — BMJ is publishing a series of 3 articles and editorials charging that the study published in The Lancet in 1998 by Andrew Wakefield and colleagues linking the childhood measles-mumps-rubella (MMR) vaccine to a "new syndrome" of regressive autism and bowel disease was not just bad science but "an elaborate fraud." According to the first article published in BMJ today by London-based investigative reporter Brian Deer, the study's investigators altered and falsified medical records and facts, misrepresented information to families, and treated the 12 children involved unethically. In addition, Mr. Wakefield accepted consultancy fees from lawyers who were building a lawsuit against vaccine manufacturers, and many of the study participants were referred by an antivaccine organization. In an accompanying editorial, BMJ Editor-in-Chief Fiona Godlee, MD, Deputy BMJ Editor Jane Smith, and Associate BMJ Editor Harvey Marcovitch write that there is no doubt that Mr. Wakefield perpetrated fraud. "A great deal of thought and effort must have gone into drafting the paper to achieve the results he wanted: the discrepancies all led in 1 direction; misreporting was gross." A great deal of thought and effort must have gone into drafting the paper to achieve the results he wanted: the discrepancies all led in 1 direction; misreporting was gross. Although The Lancet published a retraction of the study last year right after the UK General Medical Council (GMC) announced that the investigators acted "dishonestly" and irresponsibly," the BMJ editors Dr. -
Dr Fiona Godlee
QUARTER ONE / 2017 INSIGHT A QUARTERLY PUBLICATION FOR MEMBERS DR FIONA GODLEE DEMENTIA DENTISTRY ON MAKING AN APP FRIENDING DILEMMA Profile of the BMJ editor A new toolkit offers guidance What goes into the Is it ever okay to accept a and campaigning medical on providing dental care to development and testing of a Facebook Friend request from journalist dementia patients medical app? a patient? QUARTER ONE / 2017 Editor Dr Barry Parker 10 12 Managing editor Jim Killgore Associate editor Joanne Curran Editorial departments Medical Dr Richard Brittain Dental Mr Aubrey Craig Legal Simon Dinnick Design and production Connect Communications 19 0131 561 0020 www.connectmedia.cc Printing and distribution L&S Litho Correspondence Insight Editor MDDUS Mackintosh House 120 Blythswood Street Glasgow G2 4EA Photograph: Magda Rakita Photograph: [email protected] 4 MDDUS news 16 Case files QUARTER ONE / 2017 INSIGHT 6 News digest Decade of neglect, Google gaffe, A QUARTERLY PUBLICATION FOR MEMBERS Transgender records, Recurrent cancer, 8 Briefing Out of scope, He said, she said Can we reduce overtreatment? 20 Dilemma 9 Risk Do I accept a “Friend” request from Free will in consent a patient? DR FIONA GODLEE DEMENTIA DENTISTRY ON MAKING AN APP FRIENDING DILEMMA Profile of the BMJ editor A new toolkit offers guidance What goes into the Is it ever okay to accept a and campaigning medical on providing dental care to development and testing of a Facebook Friend request from journalist dementia patients medical app? a patient? 10 The accidental editor 21 Ethics COVER IMAGE Adam Campbell meets Dr Fiona A vice-like grip on virtue Nor any drop to drink, Gail Lemasurier Godlee, the forthright BMJ editor not Screenprint, 1993 afraid to take a stand 22 Addenda Gail studied fine art printmaking at Manchester Book choice: A is for arsenic, 12 Making a medical app Metropolitan University and graduated in 1990. -
Joint Statement on Public Disclosure of Results from Clinical Trials
Joint statement on public disclosure of results from clinical trials Signatories on 18 May 2017 Indian Council of Medical Research Research Council of Norway UK Medical Research Council Médecins Sans Frontières Epicentre CEPI PATH Institut Pasteur Bill and Melinda Gates Foundation Wellcome Trust Introduction The current 2013 Declaration of Helsinki states that “Every research study involving human subjects must be registered in a publicly accessible database before recruitment of the first subject.” and that “Researchers have a duty to make publicly available the results of their research .... Negative and inconclusive as well as positive results must be published or otherwise made publicly available”. In addition to the ethical imperative, poor allocation of resources for product development and financing of available interventions, and suboptimal regulatory and public health recommendations may occur where decisions are based on only a subset of all completed clinical trials. The signatories of this joint statement affirm that the prospective registration and timely public disclosure of results from all clinical trials is of critical scientific and ethical importance. Furthermore timely results disclosure reduces waste in research, increases value and efficiency in use of funds and reduces reporting bias, which should lead to better decision-making in health. Within 12 months of becoming a signatory of this statement, we each pledge to develop and implement a policy with mandated timeframes for prospective registration and public disclosure of the results of clinical trials that we fund, co-fund, sponsor or support. We each agree to monitor registration and endorse the development of systems to monitor results reporting on an ongoing basis. -
PODCAST TRANSCRIPT the RECOMMENDED DOSE with RAY MOYNIHAN | Australia.Cochrane.Org/Trd EPISODE 1
PODCAST TRANSCRIPT THE RECOMMENDED DOSE WITH RAY MOYNIHAN | australia.cochrane.org/trd EPISODE 1 - Dr Fiona Godlee, Editor-in-Chief of the BMJ (British Medical Journal) 18 October 2017 Ray Moynihan: Hello, and welcome to The Recommended Dose, a podcast encouraging a more questioning approach to healthcare. Today, it's our great privilege to feature Dr. Fiona Godlee, editor in chief of the British Medical Journal, one of the oldest and most influential journals in the world, which has a reputation for upsetting vested interests. Pushing, for example, for much greater transparency about [00:00:30] the ties between doctors and drug companies, or as Fiona says, stirring up hornets' nests. And as we'll hear, while she leads one of the top doctors' journals on the planet, owned by the British Medical Association, or BMA, she's actually not that keen on visiting doctors herself, unless it's really necessary. Fiona Godlee: I think I'm one of those people who'd rather not take pills if I don't have to, and rather not see doctors if I don't have to, so that's my bias. Ray Moynihan: [00:01:00] Whether you're a hardened researcher, a hard-working student or health professional, someone running a hospital or health system, and especially if you don't work within the world of medicine, I have no doubt you'll love listening to the BMJ's editor in chief, Fiona Godlee, and hear her stirring up a few more hornets' nests. Fiona Godlee: Well thanks Ray, I do see it as a privilege. -
Transparency in the Time of Constant Change
PhUSE 2014 Paper RG02 Transparency in the Time of Constant Change Todd Case, Biogen Idec, Cambridge MA, USA ABSTRACT The time has come, after years of hard work, to submit your application to the regulatory agency for review and possible approval! What a relief to be able to finally hand off all of your hard work and, wait a minute, ensure that all data can be reproducible?!? While CDISC has been widely adopted and its SDTM and AdAM models widely implemented, there is still the need to understand the process of ensuring that all the data is a reflection of how it was originally collected, which in some cases can be very challenging. This paper will discuss some more trending ways of both creating and presenting data in ways that ensure it is consumable and can be understood not only for analysis/submission purposes but also that post-approval it is transparent and that everyone who has a vested stake can review the data in an appropriate way. INTRODUCTION With the publication of Bad Pharma: How Medicine is Broken , and How We Can Fix it, by Dr. Ben Goldacre in 2013 a bright spotlight was shone on the data behind/supporting clinical trials. A large part of his thesis is that pharmaceutical companies exaggerate the efficacy of successful trials and that, in addition to drug companies, regulators , physicians (who are educated by the drug companies) and even patient groups have failed to protect us. Another rather striking revelation was that a clinical trial with positive results is twice more likely to be published than one with negative results (although it should be noted that this specifically is related to results – the protocol is always provided). -
Patents, Partnerships, and the Pre-Competitive Collaboration Myth in Pharmaceutical Innovation
Patents, Partnerships, and the Pre-Competitive Collaboration Myth in Pharmaceutical Innovation Liza S. Vertinsky* Public-private partnerships offer a promising alternative paradigm for pharmaceutical innovation in complex disease areas where there are both strong commercial interests and significant public need. They have the potential to reduce the tremendous waste associated with duplicative unsuccessful drug development efforts and to encourage the sharing of knowledge essential to accelerate pharmaceutical innovation. Patents threaten the potential of partnership strategies, however, by making it harder to sustain robust systems of knowledge sharing. Policymakers have tried to avoid this problem by focusing partnership strategies on areas deemed to be pre-competitive — areas of collaboration without competition and typically also without patents. This Article suggests that the current pre-competitive approach to partnership strategies in pharmaceutical innovation is fundamentally flawed for two reasons. First, it ignores the competitive market pressures that both shape what is deemed to be pre-competitive and fuel tensions * Copyright © 2015 Liza S. Vertinsky. Associate Professor of Law, Emory University School of Law. Many thanks to Timothy Holbrook, Timothy Terrell, Yaniv Heled, Cynthia Ho, Kevin Outterson, and Michael Carroll, as well as Sean O’Connor, Roger Ford, Dan Burk, Mark McKenna, and other participants of the Yale Innovation Beyond IP conference 2014; Arti Rai, Jerome Reichman, Katherine Strandburg, Brett Frischmann, Michael Madison, Peter Lee, Margaret Chon, Sonali Shah, and the other participants in the Medical Commons Workshop at NYU in May 2014 and the 2nd Thematic Conference on the Knowledge Commons at NYU in September 2014; participants in the summer workshop at Georgia State College of Law in July 2014; participants of the Emory Faculty Colloquium; Simon Stern, Abraham Drassinower, Margaret J. -
Report on Transparency and Registration in Clinical Research In
Transparency and Registration in Clinical Research in the Nordic Countries By the Nordic Trial Alliance Working Group on Transparency and Registration Transparency and Registration in Clinical Research in the Nordic Countries Nordic Trial Alliance NordForsk Stensberggata 25 NO-0170 Oslo www.nta.nordforsk.org Design: jnd.no Printed by: 07 Group ISSN 1504-8640 ER JØM KE IL T M 2 4 9 1 7 3 Trykksak Transparency and Registration in Clinical Research in the Nordic Countries By the Nordic Trial Alliance Working Group on Transparency and Registration 1 Table of Contents Preface 4 The Nordic Trial Alliance Working Group on Transparency and Registration 6 Conflicts of Interest 7 Abbreviations 8 1. Executive summary 16 2. Background 20 3. Introduction to transparency 30 4. International policies and regulations impacting the future of transparency 36 4.1 The Declaration of Helsinki 36 4.2 The Food and Drug Administration Amendments Act of 2007 36 4.3 The European Clinical Research Infrastructures Network (ECRIN) 37 4.4 European Medicines Agency 37 4.5 Horizon 2020 38 4.6 Regulation on clinical trials on medicinal product for human use 39 4.7 EU Regulation for data protection 40 5. Arguments in favour of and against transparency 44 5.1 Arguments in favour 44 5.2 Arguments against 49 6. Does publication of trial protocols or trial results in registers impede journal publications? 54 7. Registries and repositories 58 2 8. Status of the Nordic countries 62 8.1 Current national procedures for public, prospective registration and reporting of clinical -
Histories of Medical Lobbying’
‘Histories of medical lobbying’ The lobbying of government ministers by medical professionals is a live issue. In Britain and around the world medical practitioners have become active in the pursuit of legislative change. In the UK, the AllTrials campaign co-founded by the physician-researcher Ben Goldacre continues to exert pressure on parliamentarians in a bid to force greater transparency in the publication of clinical trial results. Meanwhile, the California Medical Association advocates the legalisation of the recreational use of marijuana, and doctors in Australia refuse to release child refugees from hospital into detention centres damaging to their mental health. It was precisely the lobbying of medical humanitarians such as Médecins sans Frontières in France that effected a change in the law there in 1998, permitting undocumented immigrants with life-threatening conditions to remain in the country for medical treatment. Each of these examples represents an organised attempt on the part of medical professionals to change government policy on matters related to public health – in other words, lobbying. Yet a recent announcement by the UK cabinet office suggests that henceforth recipients of public funding will be banned from directly lobbying government ministers in the hope of changing public policy. When questioned in parliament David Cameron stated that charities should be devoting themselves to ‘good causes’ rather than ‘lobbying ministers’. Unless some qualification is forthcoming, medical researchers too will be proscribed from carrying out such activity. This insinuates that lobbying is in some way outside the proper remit of researchers, medical or otherwise. Yet even a cursory glance at the history of the medical profession’s engagement with public health reveals a longstanding and significant engagement with the political process. -
SENSE ABOUT SCIENCE 14A Clerkenwell Green London EC1R 0DP T 020 7490 9590
SENSE ABOUT SCIENCE 14A Clerkenwell Green London EC1R 0DP T 020 7490 9590 Registered Charity No. 1146170 Company No. 6771027 Registered in England and Wales Response to House of Commons Science and Technology Select Committee inquiry on research integrity 10th March 2017 Sense about Science is an independent charity that challenges the misrepresentation of science and scientific evidence in public life. We advocate for openness and honesty about research findings, and work to ensure the public interest in sound science and evidence is represented and recognised in public discussion and policy making. Sense about Science runs the AllTrials campaign which calls for all past and present clinical trials to be registered and their full methods and summary results reported. The AllTrials campaign is providing a separate submission for this inquiry. However there are two other areas under the terms of this inquiry that we would like to bring the committee’s attention. A single, publicly searchable database of all government-commissioned research In June 2015 Sense about Science began an inquiry into whether the government is reporting the policy research it commissions, following a spate of accusations of suppression of inconvenient results. Led by the former Appeal Court judge, Rt Hon Sir Stephen Sedley, its report Missing Evidence was published in June 2016.1 The inquiry revealed widespread confusion in the way research commissioned by government is handled, both internally and with the public: • There are significant differences in the way departments report and record research; • 11 government departments were unable to provide a list of research they have commissioned; • Of these, seven said that they did not hold that information centrally and it would be too costly to gather. -
Improving Medicines for Children in Canada
IMPROVING MEDICINES FOR CHILDREN IN CANADA The Expert Panel on Therapeutic Products for Infants, Children, and Youth Science Advice in the Public Interest IMPROVING MEDICINES FOR CHILDREN IN CANADA The Expert Panel on Therapeutic Products for Infants, Children, and Youth ii Improving Medicines for Children in Canada THE COUNCIL OF CANADIAN ACADEMIES 180 Elgin Street, Suite 1401, Ottawa, ON, Canada K2P 2K3 Notice: The project that is the subject of this report was undertaken with the approval of the Board of Governors of the Council of Canadian Academies (the Council). Board members are drawn from the Royal Society of Canada (RSC), the Canadian Academy of Engineering (CAE), and the Canadian Academy of Health Sciences (CAHS), as well as from the general public. The members of the expert panel responsible for the report were selected by the Council for their special competencies and with regard for appropriate balance. This report was prepared for the Government of Canada in response to a request from the Minister of Health. Any opinions, findings, or conclusions expressed in this publication are those of the authors, the Expert Panel on Therapeutic Products for Infants, Children, and Youth, and do not necessarily represent the views of their organizations of affiliation or employment. Library and Archives Canada Cataloguing in Publication Library and Archives Canada Cataloguing in Publication Improving medicines for children in Canada / The Expert Panel on Therapeutic Products for Infants, Children, and Youth. Issued also in French under title: Améliorer les médicaments pour enfants au Canada. Includes bibliographical references and index. Issued in print and electronic formats. -
How Open Science Helps Researchers Succeed Abstract Open Access, Open Data, Open Source and Other Open Scholarship Practices Are Growing in Popularity and Necessity
FEATURE ARTICLE POINT OF VIEW How open science helps researchers succeed Abstract Open access, open data, open source and other open scholarship practices are growing in popularity and necessity. However, widespread adoption of these practices has not yet been achieved. One reason is that researchers are uncertain about how sharing their work will affect their careers. We review literature demonstrating that open research is associated with increases in citations, media attention, potential collaborators, job opportunities and funding opportunities. These findings are evidence that open research practices bring significant benefits to researchers relative to more traditional closed practices. DOI: 10.7554/eLife.16800.001 ERIN C MCKIERNAN*, PHILIP E BOURNE, C TITUS BROWN, STUART BUCK, AMYE KENALL, JENNIFER LIN, DAMON MCDOUGALL, BRIAN A NOSEK, KARTHIK RAM, COURTNEY K SODERBERG, JEFFREY R SPIES, KAITLIN THANEY, ANDREW UPDEGROVE, KARA H WOO AND TAL YARKONI Introduction advantage to gain more citations, media atten- Recognition and adoption of open research tion, potential collaborators, job opportunities practices is growing, including new policies that and funding opportunities. We address common increase public access to the academic literature myths about open research, such as concerns (open access; Bjo¨rk et al., 2014; Swan et al., about the rigor of peer review at open access 2015) and encourage sharing of data (open journals, risks to funding and career advance- data; Heimsta¨dt et al., 2014; Michener, 2015; ment, and forfeiture of author rights. We recog- Stodden et al., 2013), and code (open nize the current pressures on researchers, and source; Stodden et al., 2013; Shamir et al., offer advice on how to practice open science 2013).