Bio-Chemistry
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Metal Ions in Life Sciences"
I N S T R U C T I O N S F O R A U T H O R S Contributing to "Metal Ions in Life Sciences" edited by Astrid Sigel, Helmut Sigel, and Roland K. O. Sigel published by Walter de Gruyter GmbH, Berlin, Germany www.mils-WdG.com (for previous volumes visit www.bioinorganic-chemistry.org/mils) Contents 1. GENERAL REMARKS ............................................................................................... 2 2. SUBMISSION OF THE MANUSCRIPT ................................................................. 2 3. PREPARATION OF THE MANUSCRIPT ............................................................. 3 3.1. Arrangement of the Manuscript .......................................................................... 3 3.2. Organization of the Content of the Manuscript .................................................. 3 3.3. Text .................................................................................................................... 4 3.3.1. General ................................................................................................... 4 3.3.2. Further Directions ................................................................................ 4 3.4. Citations and Reference Style ............................................................................. 4 3.5. Tables ................................................................................................................. 5 3.6. Artwork ............................................................................................................... 5 3.6.1. General -
Chemistry Courses 2005-2006
Chemistry Courses 2005-2006 Autumn 2005 Chem 11101 General Chemistry I, Variant A Lee Chem 11102 General Chemistry I, Variant B Norris Chem 12200 Honors General Chemistry I Levy Chem 22000 Organic Chemistry I Yu Chem 22300 Intermediate Organic Chemistry Mrksich Chem 26100 Quantum Mechanics Mazziotti Chem 30100 Advanced Inorganic Chemistry Hopkins Chem 30900 Bioinorganic Chemistry He Chem 32100 Physical Organic Chemistry I Ismagilov Chem 32200 Organic Synthesis and Structure Rawal Chem 32600 Protein Fundamentals Piccirilli Chem 36100 Wave Mechanics & Spectroscopy Butler Chem 36400 Chemical Thermodynamics Dinner Winter 2006 Chem 11201 General Chemistry II, Variant A Scherer Chem 11202 General Chemistry II, Variant B Butler Chem 12300 Honors General Chemistry II Dinner Chem 20100 Inorganic Chemistry I Hillhouse Chem 22100 Organic Chemistry II Rawal Chem 23100 Honors Organic Chemistry II Kozmin Chem 26200 Thermodynamics Norris Chem 26700 Experimental Physical Chemistry Levy Chem 30200 Synthesis & Physical Methods in Inorganic Chemistry Jordan Chem 30400 Organometallic Chemistry Bosnich Chem 32300 Tactics of Organic Synthesis Yamamoto Chem 32400 Physical Organic Chemistry II Mrksich Chem 36200 Quantum Mechanics Freed Chem 36300 Statistical Mechanics Mazziotti Chem 38700 Biophysical Chemistry Lee Spring 2006 Chem 11301 General Chemistry III, Variant A Kozmin Chem 11302 General Chemistry III, Variant B Guyot-Sionnest Chem 20200 Inorganic Chemistry II Jordan Chem 22200 Organic Chemistry III Kent Chem 23200 Honors Organic Chemistry III Yamamoto Chem 22700 Advanced Organic / Inorganic Laboratory (8 students) He Chem 26300 Chemical Kinetics and Dynamics Sibner Chem 26800 Computational Chemistry & Biology Freed Chem 30600 Chemistry of the Elements Hillhouse Chem 31100 Supramolecular Chemistry Bosnich Chem 32500 Bioorganic Chemistry Piccirilli Chem 32900 Polymer Chemistry Yu Chem 33000 Complex Systems Ismagilov Chem 36500 Chemical Dynamics Scherer Chem 36800 Advanced Computational Chemistry & Biology Freed . -
Curriculum of Department of Pharmacy (6-Year Program)
Curriculum of Department of Pharmacy (6-year program) 1st year 2nd year 3rd year 4th year 5th year 6th year Basic Subjects for Pharmacy Student; Lectures and Practices of Basic Specialized Lectures and Practices Drug Therapy and its Related Practical Training and Beginning of Research for Graduation and SGL and more Sciences Research for Graduation Advanced Lectures Fundamental Education Professional Education Ⅰ Professional Education Ⅱ ■Humanism ■Humanism ■Preparatory Pharmacy Education ■Professional Pharmacy Education ■Practical Training ■Advanced Education Introduction to Humanism I Introduction to Humanism Ⅱ English for Pharmacy Oriental Medicine Preparation for Practical Training Research for Graduation Pharmacotherapeutics Practical Training in Hospital Advanced Clinical Training ■Preparatory Pharmacy Education ■Professional Pharmacy Education Drug Information Science Practical Training in Community Phrarmacy General Pharmacy Practice II ■Introduction of Pharmacy Basic English and English for Pharmacy Clinical Chemistry Drug Development and Production Japanese Traditional Medicine Invitation to Pharmacy Basic Statistics Synthesis of Target Molecules Pharmacy and Society ■Advanced Education Clinical Pharmacokinetics Early Exposure to Pharmacy Practical Trainings for Pharmacy Bioorganic Chemistry General Pharmacy Practice Research for Graduation Clinical Drug Evaluation Students Pharmaceutical Health Care Training Medical Economy Natural Products Chemistry ■Practical Training Education Drug Safty Evaluation and Pharmacoepidemiology -
Recreating Ancient Metabolic Pathways Before Enzymes Kamila B
Recreating ancient metabolic pathways before enzymes Kamila B. Muchowska, Elodie Chevallot-Beroux, Joseph Moran To cite this version: Kamila B. Muchowska, Elodie Chevallot-Beroux, Joseph Moran. Recreating ancient metabolic path- ways before enzymes. Bioorganic and Medicinal Chemistry, Elsevier, 2019, 27 (12), pp.2292-2297. 10.1016/j.bmc.2019.03.012. hal-02516541 HAL Id: hal-02516541 https://hal.archives-ouvertes.fr/hal-02516541 Submitted on 23 Mar 2020 HAL is a multi-disciplinary open access L’archive ouverte pluridisciplinaire HAL, est archive for the deposit and dissemination of sci- destinée au dépôt et à la diffusion de documents entific research documents, whether they are pub- scientifiques de niveau recherche, publiés ou non, lished or not. The documents may come from émanant des établissements d’enseignement et de teaching and research institutions in France or recherche français ou étrangers, des laboratoires abroad, or from public or private research centers. publics ou privés. Graphical Abstract To create your abstract, type over the instructions in the template box below. Fonts or abstract dimensions should not be changed or altered. Recreating ancient metabolic pathways Leave this area blank for abstract info. before enzymes Kamila B. Muchowskaa* , Elodie Chevallot-Berouxa, and Joseph Morana* University of Strasbourg, CNRS, ISIS UMR 7006, 67000 Strasbourg, France Bioorganic & Medicinal Chemistry journal homepage: www.elsevier.com Recreating ancient metabolic pathways before enzymes Kamila B. Muchowska,a* Elodie Chevallot-Beroux,a and Joseph Morana* a University of Strasbourg, CNRS, ISIS UMR 7006, 67000 Strasbourg, France. ARTICLE INFO ABSTRACT Article history: The biochemistry of all living organisms uses complex, enzyme-catalyzed metabolic reaction Received networks. -
CHEMISTRY Faculty Douglas A
CHEMISTRY Faculty Douglas A. Fantz, associate professor of chemistry and chair Lilia C. Harvey, interim associate vice president for academic affairs and associate dean of the college and professor of chemistry Ruth E. Riter, professor of chemistry T. Leon Venable, associate professor of chemistry Sarah A. Winget, associate professor of chemistry Agnes Scott’s academic program in chemistry, approved by the American Chemical Society (ACS), introduces students to the principles, applications, and communication of chemical knowledge and provides extensive practical experience with modern instrumentation in laboratory courses and through research opportunities. The science of chemistry concerns the structure and properties of matter with an interest in the changes that occur as matter reacts. The study of chemistry is particularly appropriate to students interested in medicine, academic or industrial scientific research, forensics, or teaching. Two major options (ACS approved or non-ACS approved track) and a minor option are available. The ACS approved major curriculum is most appropriate for students interested in entering industry or continuing their studies in graduate school. The non-ACS approved major curriculum, while rigorous, affords a student flexibility to pursue other academic interests during their time at Agnes Scott. The curriculum for majors requires a strong foundation in all five subdisciplines of chemistry (analytical, inorganic, organic, physical, and biochemistry), while allowing students to tailor upper-level requirements -
Clinical Chemistry Analyzer
Clinical Chemistry Analyzer UMDNS GMDN 16298 Analyzers, Laboratory, Clinical Chemistry, 35918 Laboratory urine analyser IVD, automated Automated 56676 Laboratory multichannel clinical chemistry analyser IVD, automated Other common names: Biochemistry analyzer Health problem addressed Perform tests on whole blood, serum, plasma, or urine samples to determine concentrations of analytes (e.g., cholesterol, electrolytes, glucose, calcium), to provide certain hematology values (e.g., hemoglobin concentrations, prothrombin times), and to assay certain therapeutic drugs (e.g., theophylline), which helps diagnose and treat numerous diseases, including diabetes, cancer, HIV, STD, hepatitis, kidney conditions, fertility, and thyroid problems. Product description Chemistry analyzers can be benchtop devices or placed on a cart; other systems require fl oor space. They are used to determine the concentration of certain metabolites, electrolytes, proteins, and/or drugs in samples of serum, plasma, urine, cerebrospinal fl uid, and/or other body fl uids. Samples are inserted in a slot or loaded onto a tray, and tests are programmed via a keypad or Use and maintenance bar-code scanner. Reagents may be stored within the analyzer, User(s): Laboratory technician and it may require a water supply to wash internal parts. Results Maintenance: Laboratory technician; are displayed on a screen, and typically there are ports to biomedical or clinical engineer connect to a printer and/or computer. Training: Initial training by manufacturer and Core medical equipment - Information Principles of operation manuals After the tray is loaded with samples, a pipette aspirates a precisely measured aliquot of sample and discharges it into the Environment of use reaction vessel; a measured volume of diluent rinses the pipette. -
A Survey of Carbon Fixation Pathways Through a Quantitative Lens
Journal of Experimental Botany, Vol. 63, No. 6, pp. 2325–2342, 2012 doi:10.1093/jxb/err417 Advance Access publication 26 December, 2011 REVIEW PAPER A survey of carbon fixation pathways through a quantitative lens Arren Bar-Even, Elad Noor and Ron Milo* Department of Plant Sciences, The Weizmann Institute of Science, Rehovot 76100, Israel * To whom correspondence should be addressed. E-mail: [email protected] Received 15 August 2011; Revised 4 November 2011; Accepted 8 November 2011 Downloaded from Abstract While the reductive pentose phosphate cycle is responsible for the fixation of most of the carbon in the biosphere, it http://jxb.oxfordjournals.org/ has several natural substitutes. In fact, due to the characterization of three new carbon fixation pathways in the last decade, the diversity of known metabolic solutions for autotrophic growth has doubled. In this review, the different pathways are analysed and compared according to various criteria, trying to connect each of the different metabolic alternatives to suitable environments or metabolic goals. The different roles of carbon fixation are discussed; in addition to sustaining autotrophic growth it can also be used for energy conservation and as an electron sink for the recycling of reduced electron carriers. Our main focus in this review is on thermodynamic and kinetic aspects, including thermodynamically challenging reactions, the ATP requirement of each pathway, energetic constraints on carbon fixation, and factors that are expected to limit the rate of the pathways. Finally, possible metabolic structures at Weizmann Institute of Science on July 3, 2016 of yet unknown carbon fixation pathways are suggested and discussed. -
Editorial Highlights for Organi Chemistry: Current Research
n ISSN: 2161-0401 Organic Chemistry: Current Research Editorial Editorial Note on Bioorganic Chemistry Sandhya Kille Department of Microbiology, Acharya Nagarjuna University, India EDITORIAL structure-function studies of therapeutics, and bio conjugates. Students focused on this area at Oregon Bioorganic chemistry could also be a rapidly growing develop a solid foundation in synthetic chemistry and even content that mixes science and biochemistry. It’s that have the good thing about the outstanding branch of bioscience that deals with the study of biochemistry/molecular biology research environment at biological processes using chemical methods. UO. Bioorganic chemistry applies the principles and Protein and enzyme function are samples of those techniques of chemistry to unravel problems of biological processes. Sometimes biochemistry is utilized relevance, taking inspiration from biology to develop new interchangeably for bioorganic chemistry; the excellence chemical processes. being that bioorganic chemistry is chemistry that's Cornell bioorganic chemists emphasize chemical and focused on the biological aspects. While biochemistry molecular approaches to solving important biological aims at understanding biological processes using problems. Research areas include the applying of chemistry, bioorganic chemistry attempts to expand synthetic and scientific discipline to the study of enzymes, organic-chemical researches (that is, structures, metabolic pathways and nucleic acids. This includes the synthesis, and kinetics) toward biology. event of mechanism-based enzyme inhibitors; elucidation When investigating metalloenzymes and cofactors, of enzyme mechanism and structure and studies of bioorganic chemistry overlaps bioinorganic chemistry. coenzyme reactivity. Chemical investigations are extended Bioorganic Chemistry and Chemical Biology, broadly to studies of receptor recognition, hormone and drug defined, are fields during which organic synthetic activity, and also the mechanism of chemical chemistry plays an unlimited role within the life sciences. -
Are Enzymes Accurate Indicators of Postmortem Interval?: a Biochemical Analysis Karly Laine Buras Louisiana State University and Agricultural and Mechanical College
Louisiana State University LSU Digital Commons LSU Master's Theses Graduate School 2006 Are enzymes accurate indicators of postmortem interval?: a biochemical analysis Karly Laine Buras Louisiana State University and Agricultural and Mechanical College Follow this and additional works at: https://digitalcommons.lsu.edu/gradschool_theses Part of the Social and Behavioral Sciences Commons Recommended Citation Buras, Karly Laine, "Are enzymes accurate indicators of postmortem interval?: a biochemical analysis" (2006). LSU Master's Theses. 177. https://digitalcommons.lsu.edu/gradschool_theses/177 This Thesis is brought to you for free and open access by the Graduate School at LSU Digital Commons. It has been accepted for inclusion in LSU Master's Theses by an authorized graduate school editor of LSU Digital Commons. For more information, please contact [email protected]. ARE ENZYMES ACCURATE INDICATORS OF POSTMORTEM INTERVAL? A BIOCHEMICAL ANALYSIS A Thesis Submitted to the Graduate Faculty of the Louisiana State University and Agricultural and Mechanical College in partial fulfillment of the requirements for the degree of Master of Arts in The Department of Geography and Anthropology by Karly Laine Buras B.S., Louisiana State University, 2001 May 2006 ACKNOWLEDGEMENTS I would like to thank the members of my thesis committee for their continued encouragement and help throughout my program. My heartfelt thanks go out to Bob Tague, Mary Manhein, and Grover Waldrop for helping me along the way. I would especially like to thank Grover Waldrop for his contributions to my thesis expenses, as well as for the use of his lab for my research. I would not have been able to do any of this without his help. -
Laboratory Classes in Bioorganic Chemistry
MINISTRY OF HEALTH OF REPUBLIC OF BELARUS VITEBSK STATE MEDICAL UNIVERSITY LABORATORY CLASSES IN BIOORGANIC CHEMISTRY L.G. Hidranovich, O.A. Khodos ( 2 - e « З Д / ) For Foreign students of the 1-st year Vitebsk 20t£ УДК 54 (042.3/4) ББК 24.239 L.G. Hidranovich, О.Л. Khodos LABORATORY CLASSES IN BIOORGANIC CHEMISTRY for foreign students of the 1-sl year: Manual./ L.G. Hidranovich, O.A. Khodos. - Vitebsk: v s m u , 20i b - 128 p. ( 2 - е м а д д ISBN 978-985-466-5$S‘-3 This issue contains program questions, problems, laboratory' works for the classes in bioorgamc chemistry, examination questions, tests, reference tables.The issue was wrote according to the typical educational program for the students o f higher medical educa tional establishments. Утверждено и рекомендовано к изданию Центральным учебно-научно методическим Советом непрерывного медицинского и фармацевтического образо вания Витебского государственного медицинского университета, 21.04________ 2007 г , протокол №4. ISBN 978-985-466-581-3 У Д К 54 (042.3/4) ББК 24.239 © Гидранович Л.Г., Ходос О А., 20/3 ©УО «Витебский государственный медицинский университет», 20'Й CONTENTS Thematic p!a:: of the lectures. 4 Thematic plan of the laboratory classes. 5 Accident prevention. 6 Theme 1. Classification and FJPAC nomenclature of organic com 7 pounds. Theme 2. Electronic structure of chemical bonds. Inductive and reso 9 nance effects. Theme 3. Stereochemistry of organic compounds. 11 Configuration and conformation of the organic compounds. Theme 4 Acid-base properties of organic compounds. 14 Theme 5. Classification and mechanisms of the reactions in organic 16 chemistry Saturated, unsaturated and aromatic hydrocarbons. -
Bioorganic Chemistry
Lecture 1. Biomedical and Bioorganic Chemistry Lecturer Yanovska Anna Olexandrivna Calculate grade: • Total (200) • General module (80 total) • Tests (Nomenclature - 10 points, Heterofunctional compounds – 14 points, Lipids – 14 points, Aminoacids, Peptides – 14 points). • Individual homework (30 possible) • 20 points (laboratory works) • 18 points work in class • Grades: • 170-200 - excellent • 169 – 140 - good • 139 – 120 – satisfied • Less than 120 - unsatisfied Organic chemistry is the chemistry of compounds of carbon. Bioorganic chemistry is the part of organic chemistry that studies the carbon compounds, which are present in the living organism – the so-called biomolecules. The major biomolecules are carbohydrates, proteins, lipids, and nucleic acids. It also studies drugs and their derivatives. By carbon chain organic compounds are classified in following way: Organic Chemistry • The chemistry of carbon compounds. • What’s special about carbon? – tetravalent (sp3 hybridization) – wide choice in oxidation states – CO2 C, +4 – CH4 C, -4 – bonds well to O, N, halides,itself,etc. – Covalent bonds are very strong Bond formation in molecules of organic compounds Functional Groups Term used to refer to parts of organic molecules where reactions tend to occur. By amount of functional groups and their type organic compounds are classified onto - Monofunctional (one functional group): alcohol C2H5-OH, carboxylic acid CH3COOH - Polyfunctional – has two or more same functional groups: HO-CH2-CH2-OH - Heterofunctional – has two or more different functional groups: HO-CH2-CH2-NH2 Functional Group is a part of an organic compound, by which it belongs to class of organic compounds and has specific properties. Structure of Carbon Compounds • There are three hybridization states and geometries found in organic compounds: – sp3 Tetrahedral – sp2 Trigonal planar – sp Linear Hydrocarbons (contain only H and C) • Four types: – Alkanes – Alkenes – Alkynes – Aromatic hydrocarbon s Alkanes • Only single bonds. -
Chiral Monolithic Silica-Based HPLC Columns for Enantiomeric
molecules Review Chiral Monolithic Silica-Based HPLC Columns for Enantiomeric Separation and Determination: Functionalization of Chiral Selector and Recognition of Selector-Selectand Interaction Mufarreh Asmari 1, Xiaoyu Wang 2 , Natalia Casado 3 , Marjan Piponski 4 , Sergiy Kovalenko 5, Liliya Logoyda 6, Rasha Sayed Hanafi 7 and Sami El Deeb 8,* 1 College of Pharmacy, King Khalid University, Abha 62529, Saudi Arabia; [email protected] 2 Department of Chemical and Biomolecular Engineering, University of Notre Dame, Notre Dame, IN 46556, USA; [email protected] 3 Departamento de Tecnología Química y Ambiental, E.S.C.E.T, Universidad Rey Juan Carlos, C/Tulipán s/n, Móstoles, 28933 Madrid, Spain; [email protected] 4 Replek Farm Ltd., st. Kozle 188, 1000 Skopje, North Macedonia; [email protected] 5 Department of Organic and Bioorganic Chemistry, Zaporizhzhia State Medical University, Maiakovskyi avenue 26, 69035 Zaporizhzhia, Ukraine; [email protected] 6 Department of Pharmaceutical Chemistry, I. Horbachevsky Ternopil National Medical University, Maidan Voli 1, 46001 Ternopil, Ukraine; [email protected] 7 Department of Pharmaceutical Chemistry, Faculty of Pharmacy and Biotechnology, German University in Citation: Asmari, M.; Wang, X.; Cairo, Cairo 11835, Egypt; rasha.hanafi@guc.edu.eg 8 Casado, N.; Piponski, M.; Kovalenko, Institute of Medicinal and Pharmaceutical Chemistry, Technische Universität Braunschweig, S.; Logoyda, L.; Hanafi, R.S.; El Deeb, 38106 Braunschweig, Germany * Correspondence: [email protected]; Tel.: +49-531-391-7301 S. Chiral Monolithic Silica-Based HPLC Columns for Enantiomeric Abstract: This review draws attention to the use of chiral monolithic silica HPLC columns for the Separation and Determination: enantiomeric separation and determination of chiral compounds.