Genes and Gene Action 2 Course Guide 2019-2020
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Genes and Gene Action 2 Course Guide 2019-2020 Course Organiser: Prof.David Finnegan Dr Elizabeth Bayne Course Email: [email protected] Name: ____________________________ If you require this document in an alternative format, such as large print or a coloured background, please contact the Biology Teaching Organisation, University of Edinburgh, James Clerk Maxwell Building, King’s Buildings, Edinburgh or email Carolyn Wilson at [email protected] ASSESSMENT DEADLINES AND FEEDBACK Assessment Available Due Feedback % of % of ICA Course mark mark Course Problem Jan 24th Feb 17th - noon Tutorial 3 12.5% 5% Lecture Quiz 1 Jan 21st - 11am Jan 28th - 11am Quiz 2 Jan 28th - 11am Feb 4th - 11am Quiz 3 Feb 4th -11am Feb 11th -11am Quiz 4 Feb 11th - 11am Feb 25th - 11am On Quiz 5 Feb 25th -11am Mar 3rd -11am submission 25% 10% Quiz 6 Mar 3rd - 11am Mar 10th -11am Quiz 7 Mar 10th -11am Mar 17th -11am Quiz 8 Mar 17th -11am Mar 24th - 11am Quiz 9 Mar 24th - 11am Mar 31st -11am PeerWise Jan 17th Day of Exam After exam 12.5% 5% Data Handling April 1 April 1 On 50% 20% Test Submission The semester 2 exam diet will run from Monday 27th April 2020 to Friday 22nd May 2020. Exam dates will be published on Monday 2nd March 2020. Who to contact if you... If you don’t know what tutorial or practical group you are in Need timetable information then check your online timetable or Learn If you still need help, ask at BTO reception. *Complete the Group Change Request form at https://www.edweb.ed.ac.uk/timetabling- examinations/timetabling/personalised-timetables/group- change-request Have a timetable clash *Please note that due to the high number of students enrolled on the course this year it may not be possible to move you to your chosen group and you may be asked to arrange to swap groups with a fellow student. Need general GGA2 information Email the course secretary: [email protected] No need to contact anyone. Check the Learn site as lecture Have missed a lecture notes and recordings are uploaded regularly. If possible speak to others who have attended and make sure that you understand any problems and solutions that Have missed a practical or tutorial have been discussed. Should any points of difficulty remain you should seek clarification from your tutor or practical leader Contact your Personal Tutor or Student Support Tutors. For Have health or personal problems details see ‘Special Circumstances’ section of the “Essential Information for Biological Science Students” Need academic advice about the Contact the Course Organiser: [email protected] course: Have a question about a specific Email the relevant Lecturer. lecture Student intranet: https://www.wiki.ed.ac.uk/display/SBSUndergraduateIntranet/School+of+Biological+Scienc es+Undergraduate+Students%27+Intranet 1 GENES AND GENE ACTION 2019 - 2020 CONTENTS Assessment deadlines 1 Aims of Course 3 Learning Objectives 3 Graduate Attributes 3 Timetable 5 Teaching Staff 6 Recommended Textbooks 7 Course discussion board 7 Structure of the Course 7 Synopsis of Lectures 8 Lecture “flipping” 10 Organisation of Practical and Tutorial Groups 11 Schedule of Practicals and Tutorials 12 Lab and Tutorial records 13 Assessment 14 PeerWise 14 Course Problem 14 Data Handling Test 15 Exam 15 Common Marking Scheme 17 Feedback (to you and from you) 18 FAQ 19 Tutorial 1 21 Tutorial 2 23 Tutorial 3 25 Tutorial 4 26 Synopsis of Practicals 29 Practical Schedule 31 Practical 1 32 Practical 2 36 Practical 3 46 Practical 4 55 Practical 5 59 Further Information 65 2 GENES AND GENE ACTION 2 2019-2020 This guide should be used in conjunction with information and learning support material available on Learn. AIMS OF THE COURSE The course aims to provide an introduction to modern genetics to prepare students for third year courses. This is achieved through an integrated series of lectures, practicals and tutorials designed to give an appreciation of the systems and methods used for classical genetic and molecular genetic analysis. LEARNING OUTCOMES As a result of successfully completing this course you should: 1] be able to explain how genetics is used to analyse a variety of biological phenomena. 2] be able to carry out genetic experiments and to analyse and interpret the results of these experiments. 3] be able to solve genetic problems related to the topics covered during the course 4] be able to use collaborative learning to develop your personal effectiveness. DEVELOPMENT OF “GRADUATE ATTRIBUTES’ The University has identified a set of four clusters of skills and abilities that students should develop throughout their degree programme to strengthen your attitude towards lifelong learning and personal development, as well as future employability. The graduate attributes we hope to develop with the Genes and Gene Action 2 course are indicated below. Research and Enquiry This course aims to increase your understanding of classic, modern and molecular genetics and also your problem solving skills. The knowledge obtained, and the development of research and technical skills, will be of benefit to you during the rest of your degree and beyond. The course will develop your research and problem solving capabilities through your work on the course problem and the data handling test, and the feedback that you will obtain from these tasks. Staff will assist you to learn and practice problem-solving skills during tutorials and practicals throughout the course. Personal and Intellectual Autonomy You are expected to take responsibility for your own learning and to work independently to meet the challenges of the course. You are expected to explore textbooks, and occasionally research papers, not only to expand your knowledge of the topics covered in the lectures, but to broaden your understanding of areas of genetics that interest you. You are encouraged to discuss the course problem and questions in the tutorials and practicals with other students but answers that you submit must be entirely your own work. You are also responsible for making your own record of practical and tutorial exercises. These are integral part of the course and will help you when preparing for both the data handling test and the degree exam while peer marking of the course problem will develop your ability to assess the ideas of others. 3 Communication Through discussion and collaboration with students in practical and tutorial groups you will be able to communicate your views and ideas and to learn from your peers. Genes and Gene Action has an active Learn discussion board and you can benefit greatly from participating. You are also required, as part of the course assessment, to engage in peer marking, and to use the online PeerWise system to share and discuss course related questions. The opportunities to benefit academically from such communications are proven and considerable. Personal Effectiveness Throughout your degree programme you will learn transferable skills that will benefit you not only across the courses you are enrolled in, but in future employment and further study. In this course, as in others, time management is an important skill that you will learn as you develop ways to organise your work and meet deadlines. Effective participation in the Peer wise exercise, for example, requires that you submit your questions reasonably early in the course in order to allow others to answer, comment and discuss your questions with you. Working effectively as a member of a group is an important transferable skill. This will be enhanced by collaborating with other students in tutorials and practicals. This will help you become aware of your skills and talents (and possibly your limitations) and to develop your own scientific style. 4 TIMETABLE Week Date Lectures and Quectures Practicals Tutorials Quizzes Title Lecturer # Groups Tutors Start End 14-Jan 1: Introduction – DF DF – – – – 1 15-Jan – – Practical 1 – Group 1 (am); Group 2 (pm) – – – 16-Jan 2: Recombination and Maps 1 DF – – – – 17-Jan 3: Recombination and Maps 2 DF – – – – 21-Jan 4: Recombination and Maps 3 DF – – – Quiz 1 – 2 22-Jan – – Practical 1 – Group 3 (am) 1 A to F HW, HM, AD, JG, DF, VM 23-Jan 5: Thinking about Genes DF Practical 1 – Group 4 (pm) 1 G, H & Q HW, KH, JS 24-Jan 6: Mendelian Genetic Analysis HM – – – 28-Jan 7: Chromosome Structure HM 1 S DF Quiz 2 Quiz 1 3 29-Jan – – Practical 2 – Group 1 (am); Group 2 (pm) 1 I to N HW, HM, AD, JG, DF, VM 30-Jan 8: Eukaryotic Genes and Genomes HM – 1 O, P & R HW, KH, JS 31-Jan 9: Genetic Interactions HM – – – – 04-Feb 10: DNA Replication MeK – – – – Quiz 3 Quiz 2 4 05-Feb – – Practical 2 – Group 3 (am) 2 A to F HW, HM, AD, JG, DF, VM 06-Feb 11: Mutation, Mutagenesis and Repair MeK Practical 2 – Group 4 (pm) 2 G, H & Q HW, KH, JS 07-Feb 12: Gene Expression: Transcription and Translation MeK – – – – 11-Feb 13: The Prokaryotic Gene: structure and regulation MeK – 2 S DF Quiz 4 Quiz 3 5 12-Feb – – Practical 3 – Group 1 (am); Group 2 (pm) 2 I to N HW, HM, AD, JG, DF, VM 13-Feb 14: The Genetic Code and Consequencs of Mutation MeK – 2 O, P & R HW, KH, JS 14-Feb 15: Plasmids DL – – – – 18-Feb No quiz – 19-Feb 20-Feb Flexible Learning Week 21-Feb 25-Feb 16: Bacterial Transpsons DL – – – Quiz 5 Quiz 4 6 26-Feb – – Practical 3 – Group 3 (am) 3 A to F HW, HM, AD, JG, DF, VM 27-Feb 17: Conjugation DL Practical 3 – Group 4 (pm) 3 G, H & Q HW, KH, JS 28-Feb 18: Transduction and Transformation DL – – – 03-Mar 19: Mid-semester feedback and Revision Session DF, MeK, DL HM – 3 S DF Quiz 6 Quiz 5 7 04-Mar – – Practical 4 – Group 1 (am); Group 2(pm) 3 I to