DOCSLIB.ORG

Abstract Book RCAW 2015 03 20 Book.Pdf

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text

Load more

2015 We would like to give a special thanks to ECU School of Art and Design graphic design undergraduate student Kristen Bitar, for her cover design, poster, and program art. We would also like to recognize Master of Adult Education student Laura Taylor and Doctoral of Physics student Taylor Dement, for their development and managment of the program. 4 2015 | RCAW East Carolina University® Division of Research & March 2015 Graduate Studies Greenville Centre Ste 1500 2200 S. Charles Blvd Greetings! Mailstop 157 Greenville, NC 27858-4353 I am pleased to invite you to participate in the East Carolina University Research and Creative Achievement Week (RCAW). The week of March 23-27, 2015, has been set aside to highlight the extraordinary accomplishments of our students in research and creative activities. It is the hope of the organizing committee Michael R. Van Scott, PhD Institutional Official & Chief that you will attend, as much as your time allows, in order to see and hear what our students have achieved. Research Officer; In addition, we hope that you will strongly encourage your students to attend. The event is sponsored by a Associate Vice Chancellor, Interim 252-328-9471 partnership of these entities: Division of Academic Affairs, Division of Health Sciences, Brody Graduate Student 252-328-2769 fax Association, Graduate and Professional Student Senate, Office of Undergraduate Research, Office of Postdoctoral Affairs, Graduate School, and Division of Research & Graduate Studies. Research and Creative Achievement Week is a showcase of graduate and undergraduate student research and creative activities that are taking place here at ECU. There will be over 375 student presentations, an impressive number that reflects the current growth in research and creative activities at ECU in a variety of fields and disciplines. Oral and poster presentations will take place on Monday, March 23 (Graduate Presentation Day); Tuesday, March 24 (Postdoctoral Scholar presentations); and Wednesday, March 25 (Undergraduate Presentation Day) with most posters on display for an additional day each. In addition, we have online presentations for both undergraduate and graduate students. This year, we are making an emphasis on student and student-faculty collaborative work. The Honors College Research Poster Showcase is a new event to be held on Tuesday evening. The International Scholars Symposium will take place on Tuesday afternoon. The College of Education Faculty and Student Research Showcase will be on Wednesday afternoon. The Scholar-Teacher Awards and Symposium at which faculty will be recognized for the integration of research into their teaching will be held on Thursday, March 26. The whole week is capped off with the announcement of the student and postdoctoral scholar award winners at noon on Friday, March 27. Please consider encouraging your classes to attend specific discipline-related oral student presentations on Monday, Tuesday, and Wednesday or to view the poster presentations Monday through Thursday. Visit the RCAW blog at http://blog.ecu.edu/sites/rcaw/ for a schedule of events (click on Schedule). What an exciting week and a great experience for our students! We look forward to seeing you at Mendenhall Student Center and participating in these events. Michael R. Van Scott 2015 | RCAW 5 6 2015 | RCAW Table of Contents 05 Letter from Vice Chancellor, Michael R. Van Scott 09 Program Sponsors 10 Research and Creative Achievement Week Committees 11 Event Schedule 13 Lectures and Symposia 29 Mentor Listing 30 Student Presenter Schedule 30 Graduate Oral Presentations 35 Graduate Poster Presentations 42 Online Poster Presentations 43 Postdoctoral Poster Presentations 44 Undergraduate Oral Presentations 47 Undergraduate Poster Presentations 56 Graduate Abstracts 56 Oral Presentations 82 Poster Presentations 130 Online Presentations 132 Postdoctoral Abstracts 132 Poster Presentations 136 Undergraduate Abstracts 136 Oral Presentations 148 Poster Presentations 194 Presenters’ Index 2015 | RCAW 7 8 2015 | RCAW Program Sponsors Division of Academic Affairs Division of Health Sciences Brody Graduate Student Association Graduate and Professional Student Senate Office of Undergraduate Research Office of Postdoctoral Affairs Graduate School Division of Research and Graduate Studies 2015 | RCAW 9 Planning Committee Tom McConnell: The Graduate School, RCAW Chair Melani Duffrin: Nutrition and Dietetics, College of Human Ecology Mary Farwell: Biology, Office of Undergraduate Research, RCAW Co-Chair Nehad Elsawaf: Economics, Thomas Harriot College of Arts and Sciences Abbie Brown: Mathematics, Science, and Instructional Technology Education, College of Education Rich Franklin: Microbiology & Immunology, Brody School of Medicine Virginia Carraway-Stage: Nutrition Science, College of Human Ecology Derrick Isler: The Graduate School Bob Chin: Technology Systems, College of Engineering and Donna Kain: English, Thomas Harriot College of Arts and Sciences Technology Margaret Pio: Research & Graduate Studies Thomas Croskery: President, Graduate & Professional Student Senate, Mathematics, Thomas Harriot College of Arts and Sciences Alan Skirnick: English Student, Thomas Harriot College of Arts and Sciences Taylor Dement: Biomedical Physics Student, Thomas Harriot College of Arts and Sciences Laura Taylor: Adult Education Student, College of Education Nicole Devaul: President, Brody Graduate Association, Anatomy and Joseph Wilck: Engineering, College of Technology and Computer Cell Biology, Brody School of Medicine Science Paul DeVita: Kinesiology, College of Health and Human Performance Guili Zhang: Special Education, Foundations & Research, College of Education Christyn Dolbier: Psychology, Thomas Harriot College of Arts and Sciences Technical Committee Josh Brown, Tony Cooke, Wendy Creasey, Laurie Godwin, Derrick Isler, Charlie Justice, Matthew Powell, Ginny Sconiers, John Southworth 10 2015 | RCAW March Twenty-Third — March Twenty-Seventh MARCH TWENTY-THIRD 8:15 am – 5:30 pm | Graduate Student Presentations Oral sessions in MSC Great Rooms 1+2+3 Graduate Posters in MSC Social Room Graduate Posters in MSC 221 Graduate Posters in MSC Gallery Monday 12:15 pm – 1:15 pm | USPTO Patent Presentation| MSC 244 MARCH TWENTY-FOURTH 9:00 am – 11:00 am | Intersection of Arts and Sciences | MSC 244 7:30 am – 12:00 pm | Graduate Posters | Posters taken down by 12 pm 10:00 am – 12:00 pm | Postdoctoral Scholar Posters | MSC Great Room 2 2:30 pm – 6:00 pm | International Scholars Symposium | MSC 244 Tuesday 6:30 pm - 8:30 pm | Honors College Research Poster Showcase and Reception | MSC Great Rooms MARCH TWENTY-FIFTH 8:15 am – 4:00 pm | Undergraduate Student Presentations Oral Sessions | MSC Great Rooms 1+2 Undergraduate Posters | MSC Social Room Undergraduate Posters | MSC 221 Undergraduate Posters | MSC Gallery 4:00 pm – 6:00 pm | Invited Faculty Research Lecture Wednesday College of Education Faculty and Student Research Showcase | MSC 244 MARCH TWENTY-SIXTH 7:30 am – 3:00 pm | Undergraduate Posters | Posters taken down after 2 pm 12:00 pm – 1:15 pm | Scholar-Teacher Luncheon (Invitation Only) | MSC Great Rooms 2+3 1:30 pm – 3:15 pm | Scholar-Teacher Symposium | MSC Great Room 1 & MSC 244 Thursday MARCH TWENTY-SEVENTH 12:00 pm – 1:30 pm | Student Awards Luncheon (Invitation Only) | MSC Great Rooms 1+2+3 RCAW Awards Thesis/Dissertation Awards Friday ECU Distinguished Faculty Mentor Awards Excellence in Health Disparities Carol F. Volkman Recognition 2015 | RCAW 11 12 2015 | RCAW Lectures & Symposia College of Education Faculty and Student Research Showcase ECU Scholar-Teacher Awards and Symposium Global Issues Virtual Conference Honors College Research Poster Showcase and Reception International Scholars Symposium Intersection of Arts and Sciences USPTO Patent Presentation 2015 | RCAW 13 14 2015 | RCAW College of Education Faculty and Student Research Showcase Date: W e d n e s d a y , March 25, 2015 Time: 4:00 PM - 6:00 PM L o c a t i o n : M S C 2 4 4 Presenters and Research Studies: F a c u l t y i n v i t e d p a p e r p r e s e n t a t i o n ( 4 : 1 5 - 4 : 4 5 ) : Benjamin Blaisdell, Schools as racial spaces: Understanding and resisting structural racism F a c u l t y i n v i t e d r o u n d t a b l e p r e s e n t a t i o n ( 5 : 0 0 - 5 : 4 5 ) : Abbie Brown, 3D Printing in Instructional Settings: Identifying A Curricular Hierarchy of Activities Christina Tschida, It Just Works Better: Introducing the 2:1 Model of Co-Teaching in Teacher Preparation G r a d u a t e s t u d e n t p o s t e r p r e s e n t a t i o n s ( 5 : 0 0 - 5 : 4 5 ) : The Effects of Background Music on Student Work Thinking Maps and Latin Instruction Catherine Bademian Kristin Justice The Effectiveness of Technology on Reading in the Multiplication Fact Fluency: Traditional Instructional Classroom Practices versus iPad/Web Based Applications Jennifer Burleson Lisa Howell Langley Explicit Instruction vs. Student Led Learning Literature Based Instruction vs. Phonics in Isolation Experiences Ashley Lynn Kathryn V. Cayco Does Integrating the Arts, Specifically Music, into the The Effects of Music in the Elementary Classroom Math Class, Increase Student Performance? Audrey Dexter Heather Marshall Stability Balls in the Classroom – Does Usage Reading Comprehension Strategies Increase Student Achievement Blythe McGowan Samantha Dinner Singapore Math: The Modeling of Word Problems Best Small Group Reading Instruction Method for Tracy Lynn McIntyre Upper Elementary: Guided Reading or Literature
Recommended publications
  • Human Small Maf Proteins Form Heterodimers with CNC Family Transcription Factors and Recognize the NF-E2 Motif

    Human Small Maf Proteins Form Heterodimers with CNC Family Transcription Factors and Recognize the NF-E2 Motif

    Oncogene (1997) 14, 1901 ± 1910 1997 Stockton Press All rights reserved 0950 ± 9232/97 $12.00 Human small Maf proteins form heterodimers with CNC family transcription factors and recognize the NF-E2 motif Tsutomu Toki1, Jugou Itoh2, Jun'ichi Kitazawa1, Koji Arai1, Koki Hatakeyama3, Jun-itsu Akasaka4, Kazuhiko Igarashi5, Nobuo Nomura6, Masaru Yokoyama1, Masayuki Yamamoto5 and Etsuro Ito1 1Department of Pediatrics, 2Medicine, School of Medicine; 3Department of Biology, Faculty of Sciences, Hirosaki University, Hirosaki 036; 4Department of Biochemistry, Tohoku University School of Medicine, Sendai 980-77; 5Center for TARA and Institute of Basic Medical Sciences, University of Tsukuba, Tsukuba 305; 6Kazusa DNA Institute, Kisarazu 292, Japan The transcription factor NF-E2, a heterodimeric protein Talbot et al., 1990; Talbot and Grosveld, 1991; complex composed of p45 and small Maf family Kotkow and Orkin, 1995). Recent analyses demon- proteins, is considered crucial for the regulation of strated that NF-E2 is composed of two subunits erythroid gene expression and platelet formation. To (Andrews et al., 1993a,b; Igarashi et al., 1994). The facilitate the characterization of NF-E2 functions in large p45 subunit belongs to a family of basic leucine- human cells, we isolated cDNAs encoding two members zipper (bZip) proteins that is closely related to the of the small Maf family, MafK and MafG. The human Drosophila Cap`n'colar (the CNC family) factor mafK and mafG genes encode proteins of 156 and 162 (Mohler et al., 1991). It cannot bind to the NF-E2 amino acid residues, respectively, whose deduced amino sequence as a homodimer, but does do after forming acid sequences show approximately 95% identity to their heterodimers with chicken small Maf family proteins, respective chicken counterparts.
  • A Comprehensive Survey of Trends in Oracles for Software Testing

    A Comprehensive Survey of Trends in Oracles for Software Testing

    1 A Comprehensive Survey of Trends in Oracles for Software Testing Mark Harman, Phil McMinn, Muzammil Shahbaz and Shin Yoo Abstract—Testing involves examining the behaviour of a system in order to discover potential faults. Determining the desired correct behaviour for a given input is called the “oracle problem”. Oracle automation is important to remove a current bottleneck which inhibits greater overall test automation; without oracle automation, the human has to determine whether observed behaviour is correct. The literature on oracles has introduced techniques for oracle automation, including modelling, specifications, contract-driven development and metamorphic testing. When none of these is completely adequate, the final source of oracle information remains the human, who may be aware of informal specifications, expectations, norms and domain specific information that provide informal oracle guidance. All forms of oracle, even the humble human, involve challenges of reducing cost and increasing benefit. This paper provides a comprehensive survey of current approaches to the oracle problem and an analysis of trends in this important area of software testing research and practice. Index Terms—Test oracle; Automatic testing; Testing formalism. F 1 INTRODUCTION undecidable problem. For example, attempting to cover all branches [6], [10], [16], [64], [77], Much work on testing seeks to automate as [159], [177] in a system under test can never be much of the test process as practical and de- complete because branch reachability is known sirable, in order to make testing faster, cheaper to be undecidable in general [192]. and more reliable. In order to automate testing, The problem of generating test inputs to we need an oracle, a procedure that determines achieve coverage of test adequacy criterion what the correct behaviour of a system should has been the subject of research interest for be for all input stimuli with which we wish nearly four decades [48], [106] and has been to subject the system under test.
  • Β-Cell-Specific Mafk Overexpression Impairs Pancreatic Endocrine Cell Development

    Β-Cell-Specific Mafk Overexpression Impairs Pancreatic Endocrine Cell Development

    RESEARCH ARTICLE β-Cell-Specific Mafk Overexpression Impairs Pancreatic Endocrine Cell Development Ahmed M. Abdellatif1,2, Hisashi Oishi1,3,4*, Takahiro Itagaki1,3, Yunshin Jung1,3, Hossam H. Shawki1,3, Yukari Okita5, Yoshikazu Hasegawa3, Hiroyuki Suzuki5, Salah E. El-Morsy2, Mesbah A. El-Sayed2, Mahmoud B. Shoaib2, Fumihiro Sugiyama3, Satoru Takahashi1,3,4,6* 1 Department of Anatomy and Embryology, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan, 2 Department of Anatomy and Embryology, Faculty of Veterinary Medicine, Mansoura University, Mansoura, Egypt, 3 Laboratory of Animal Resource Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan, 4 Life Science Center, Tsukuba Advanced Research Alliance (TARA), University of Tsukuba, Tsukuba, Ibaraki, Japan, 5 Department of Experimental Pathology, Faculty of Medicine, University a11111 of Tsukuba, Tsukuba, Ibaraki, Japan, 6 International Institute for Integrative Sleep Medicine (WPI-IIIS), University of Tsukuba, Tsukuba, Ibaraki, Japan * [email protected] (ST); [email protected] (HO) Abstract OPEN ACCESS Citation: Abdellatif AM, Oishi H, Itagaki T, Jung Y, The MAF family transcription factors are homologs of v-Maf, the oncogenic component of Shawki HH, Okita Y, et al. (2016) β-Cell-Specific Mafk the avian retrovirus AS42. They are subdivided into 2 groups, small and large MAF proteins, Overexpression Impairs Pancreatic Endocrine Cell according to their structure, function, and molecular size. MAFK is a member of the small Development. PLoS ONE 11(2): e0150010. MAF family and acts as a dominant negative form of large MAFs. In previous research we doi:10.1371/journal.pone.0150010 generated transgenic mice that overexpress MAFK in order to suppress the function of Editor: Bridget Wagner, Broad Institute of Harvard large MAF proteins in pancreatic β-cells.
  • Leadership and Democracy

    Leadership and Democracy

    HIGHER EDUCATION EXCHANGE 2019 Leadership and Democracy Articles Maura Casey Michaela Grenier Matthew R. Johnson William V. Muse and Carol Farquhar Nugent Mark Wilson Interviews Dennis Donovan and Harry C. Boyte Katrina S. Rogers and Keith Melville Afterword David Mathews Editors: Derek W. M. Barker and Alex Lovit Managing Editor: Joey Easton Proofreader: Ellen Dawson-Witt Formatting: Long’s Graphic Design, Inc. The Higher Education Exchange is founded on a thought articulated by Thomas Jefferson in 1820: I know no safe depository of the ultimate powers of the society but the people themselves; and if we think them not enlightened enough to exercise their control with a wholesome discretion, the remedy is not to take it from them, but to inform their discretion by education. In the tradition of Jefferson, the Higher Education Exchange agrees that a central goal of higher education is to help make democracy possible by preparing citizens for public life. The Higher Education Exchange is part of a movement to strengthen higher education’s democratic mission and foster a more democratic culture throughout American society. Working in this tradition, the Higher Education Exchange publishes case studies, analyses, news, and ideas about efforts within higher education to develop more democratic societies. The Kettering Foundation is a nonprofit operating foundation, chartered in 1927, that does not make grants but welcomes partnerships with other institutions (or groups of institutions) and individuals who are actively working on problems of communities, governing, politics, and edu- cation. The interpretations and conclusions contained in the Higher Education Exchange, unless expressly stated to the contrary, represent the views of the author or authors and not necessarily those of the foundation, its trustees, or officers.
  • Novel Insights Into the Regulation of the Antioxidant Response Element

    Novel Insights Into the Regulation of the Antioxidant Response Element

    Novel insights into the regulation of the antioxidant response element mediated gene expression by electrophiles: induction of the transcriptional repressor BACH1 by NRF2 Henna-Kaisa Jyrkkänen, Suvi M Kuosmanen, Merja Heinäniemi, Heidi Laitinen, Emilia Kansanen, Eero Mella-Aho, Hanna Leinonen, Seppo Ylä-Herttuala, Anna-Liisa Levonen To cite this version: Henna-Kaisa Jyrkkänen, Suvi M Kuosmanen, Merja Heinäniemi, Heidi Laitinen, Emilia Kansanen, et al.. Novel insights into the regulation of the antioxidant response element mediated gene expression by electrophiles: induction of the transcriptional repressor BACH1 by NRF2. Biochemical Journal, Portland Press, 2011, 440 (2), pp.167-174. 10.1042/BJ20110526. hal-00642837 HAL Id: hal-00642837 https://hal.archives-ouvertes.fr/hal-00642837 Submitted on 19 Nov 2011 HAL is a multi-disciplinary open access L’archive ouverte pluridisciplinaire HAL, est archive for the deposit and dissemination of sci- destinée au dépôt et à la diffusion de documents entific research documents, whether they are pub- scientifiques de niveau recherche, publiés ou non, lished or not. The documents may come from émanant des établissements d’enseignement et de teaching and research institutions in France or recherche français ou étrangers, des laboratoires abroad, or from public or private research centers. publics ou privés. Biochemical Journal Immediate Publication. Published on 03 Aug 2011 as manuscript BJ20110526 NOVEL INSIGHTS INTO THE REGULATION OF THE ANTIOXIDANT RESPONSE ELEMENT MEDIATED GENE EXPRESSION BY ELECTROPHILES: INDUCTION OF THE TRANSCRIPTIONAL REPRESSOR BACH1 BY NRF2 Henna-Kaisa Jyrkkänen1, Suvi Kuosmanen2, Merja Heinäniemi3, Heidi Laitinen1, Emilia Kansanen1, Eero Mella-Aho1, Hanna Leinonen1, Seppo Ylä-Herttuala1, Anna-Liisa Levonen1* 1Department of Biotechnology and Molecular Medicine, A.
  • Organization and Committees

    Organization and Committees

    Committees General Chair Aleksander Spivakovsky, Verkhovna Rada of Ukraine, Kherson State University, Ukraine Steering Committee Vadim Ermolayev, Zaporizhzhya National University, Ukraine Heinrich C. Mayr, Alpen-Adria-Universät Klagenfurt, Austria Mykola Nikitchenko, Taras Shevchenko National University of Kyiv, Ukraine Aleksander Spivakovsky, Verkhovna Rada of Ukraine, Kherson State University, Ukraine Mikhail Zavileysky, DataArt, Russian Federation Grygoriy Zholtkevych, V.N.Karazin Kharkiv National University, Ukraine Program Chairs Nick Bassiliades, Aristotle University of Thessaloniki, Greece Vadim Ermolayev, Zaporizhzhya National University, Ukraine Proceedings Chairs Hans-Georg Fill, Universität Wien, Austria Vitaliy Yakovyna, Lviv Polytechnic National University, Ukraine Presentations Chair Heinrich C. Mayr, Alpen-Adria-Universät Klagenfurt, Austria Workshops Chair Vyacheslav Kharchenko, National Aerospace University “KhAI”, Ukraine Poster and Demo Chair Yaroslav Prytula, Ukrainian Catholic University, Ukraine PhD Symposium Chairs Grygoriy Zholtkevych, V.N. Karazin Kharkiv National University, Ukraine Frédéric Mallet, Université Cote d’Azur, Cnrs, Inria, I3S, France IT Talks Chairs Aleksander Spivakovsky, Verkhovna Rada of Ukraine, Kherson State University, Ukraine Mikhail Zavileysky, DataArt, Russian Federation Local Organization Chairs Anatoly Anisimov (chair), Taras Shevchenko National University of Kyiv, Ukraine Mykola Nikitchenko (chair), Taras Shevchenko National University of Kyiv, Ukraine Volodymyr Shevchenko (vice-chair),
  • The Roles of NFE2L1 in Adipocytes

    The Roles of NFE2L1 in Adipocytes

    The roles of NFE2L1 in adipocytes: Structural and mechanistic insight from cell and mouse models Suping Ren, China Medical University Yiying Bian, China Medical University Yongyong Hou, China Medical University Zhendi Wang, China Medical University Zhuo Zuo, China Medical University Zhiyuan Liu, China Medical University Yue Teng, Harbin Medical University Jingqi Fu, China Medical University Huihui Wang, China Medical University Yuanyuan Xu, China Medical University Only first 10 authors above; see publication for full author list. Journal Title: Redox Biology Volume: Volume 44 Publisher: Elsevier Inc | 2021-08-01, Pages 102015-102015 Type of Work: Article | Final Publisher PDF Publisher DOI: 10.1016/j.redox.2021.102015 Permanent URL: https://pid.emory.edu/ark:/25593/vm003 Final published version: http://dx.doi.org/10.1016/j.redox.2021.102015 Copyright information: © 2021 The Authors This is an Open Access work distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (https://creativecommons.org/licenses/by-nc-nd/4.0/). Accessed September 30, 2021 6:05 PM EDT Redox Biology 44 (2021) 102015 Contents lists available at ScienceDirect Redox Biology journal homepage: www.elsevier.com/locate/redox The roles of NFE2L1 in adipocytes: Structural and mechanistic insight from cell and mouse models Suping Ren a, Yiying Bian a, Yongyong Hou a, Zhendi Wang a, Zhuo Zuo a, Zhiyuan Liu a, Yue Teng b, Jingqi Fu a, Huihui Wang c, Yuanyuan Xu c, Qiang Zhang d, Yanyan Chen e,**, Jingbo Pi a,* a Program of Environmental Toxicology, School of Public Health, China Medical University. No. 77 Puhe Road, Shenyang North New Area, Shenyang, Liaoning, 110122, China b Department of Hepatopancreatobiliary Surgery, The Forth Affiliated Hospital, Harbin Medical University, Harbin, China c Group of Chronic Disease and Environmental Genomics, School of Public Health, China Medical University, No.
  • Research and Creative Achievement Week 2011

    Research and Creative Achievement Week 2011

    East Carolina2011 Universi ty : Research and Creative Achievement Week 2011 East Carolina University Creating a Better Tomorrow 5th Annual Research & Creative Achievement Week Mendenhall Student Center April 4 – 8 2011 1 East Carolina University : Research and Creative Achievement Week 2011 Research and Creative Achievement Week April 4 – 8, 2011 Mendenhall Student Center 2 East Carolina University : Research and Creative Achievement Week 2011 Research and Creative Achievement Week Table of Contents Letter from Vice Chancellor Deirdre M. Mageean…………………………... 4 Program Sponsors……………………………………………………………. 6 Research and Creative Achievement Week Planning Committee…………… 7 Research and Creative Achievement Week Subcommittees………………… 8 Schedule of Events…………………………………………………………… 9 Faculty Recognition: Research and Creative Activity……………………….. 12 Faculty Recognition: Inventor Discovery……………………………………. 17 Lectures and Symposia………………………………………………………. 18 Presentation of Awards………………………………………………………. 29 Index: Judges…………………………………………………………………. 32 Index: Mentors……………………………………………………………….. 34 Oral and Poster Presentation Sessions……………………………………… 38 Graduate Abstracts: Online, Oral, and Poster………………………………... 64 Undergraduate Abstracts: Online, Oral, and Poster………………………….. 174 3 East Carolina University : Research and Creative Achievement Week 2011 Letter from the Vice Chancellor March 2011 Dear ECU Community: The Division of Research and Graduate Studies invites you to participate in the ECU Research and Creative Achievement Week on the campus of East Carolina University. The week of April 4-8, 2011, has been set aside to highlight the extraordinary accomplishments of our students in research and creative activities. Because the number of events has increased, events will also be held the previous week. It is the hope of the organizing committee that you will attend, as much as your time allows, in order to see and hear what our students have achieved.
  • GATA2-Dependent and Region-Specific Regulation of Gata2

    GATA2-Dependent and Region-Specific Regulation of Gata2

    GATA2-dependentBlackwellAutoregulationD Nozawa Publishing et al. of Gata2 Inc gene in midbrain and region-specific regulation of Gata2 transcription in the mouse midbrain Daisuke Nozawa1,2†, Norio Suzuki1,2†, Maki Kobayashi-Osaki1,2, Xiaoqing Pan1,2,3, James Douglas Engel4 and Masayuki Yamamoto1,2,3* 1Center for Tsukuba Advanced Research Alliance, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8577, Japan 2Department of Molecular and Developmental Biology, Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8577, Japan 3Department of Medical Biochemistry, Tohoku University Graduate School of Medicine, 2-1 Seiryo-cho, Aoba-ku, Sendai 980-8575, Japan 4Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI 48109-2200, USA Transcription factor GATA2 is expressed in numerous mammalian tissues, including neural, hemato- poietic, cardiovascular and urogenital systems, and yet it plays important roles in the regulation of tissue-restricted gene expression. The Gata2 gene itself is also under stringent tissue-specific control and multiple cis-regulatory domains have been identified in the Gata2 locus. In this study we sought out and then examined in detail the domains that regulate Gata2 in the midbrain. We identified two discrete domains in the Gata2 promoter that direct midbrain expression; these distal 5H and proximal 2H regulatory domains are located 3.0 and 1.9 kbp, respectively, upstream of the transcriptional initiation site. Importantly, both domains contain GATA factor binding sites. Our analyses further revealed that GATA2 is essential for Gata2 gene expression in the midbrain, whereas GATA3 is not. Both the 2H and 5H domains have the independent ability to activate Gata2 gene expression in the midbrain superior colliculus, whereas the distal-5H domain is additionally capable of activating Gata2 transcription in the inferior colliculus.
  • HTLV-1 Basic Leucine Zipper Factor Protects Cells from Oxidative Stress by Upregulating Expression of Heme Oxygenase I

    HTLV-1 Basic Leucine Zipper Factor Protects Cells from Oxidative Stress by Upregulating Expression of Heme Oxygenase I

    RESEARCH ARTICLE HTLV-1 basic leucine zipper factor protects cells from oxidative stress by upregulating expression of Heme Oxygenase I 1 1 1 1 Amanda W. RushingID *, Blake RushingID , Kimson HoangID , Stephanie V. SandersID , 2 1 1 Jean-Marie PeÂloponèse, Jr.ID , Nicholas PolakowskiID , Isabelle LemassonID * 1 Department of Microbiology and Immunology, Brody School of Medicine, East Carolina University, Greenville, North Carolina, United States of America, 2 Institut de Recherche en Infectiologie de Montpellier, Centre National de la Recherche Scientifique, Universite de Montpellier, Montpellier, France a1111111111 * [email protected] (AWR); [email protected] (IL) a1111111111 a1111111111 a1111111111 a1111111111 Abstract Adult T-cell Leukemia (ATL) is a lymphoproliferative disease of CD4+ T-cells infected with Human T-cell Leukemia Virus type I (HTLV-1). With the exception of allogeneic hematopoi- etic stem cell transplantation, there are no effective treatments to cure ATL, and ATL cells OPEN ACCESS often acquire resistance to conventional chemotherapeutic agents. Accumulating evidence Citation: Rushing AW, Rushing B, Hoang K, shows that development and maintenance of ATL requires key contributions from the viral Sanders SV, PeÂloponèse J-M, Jr., Polakowski N, et protein, HTLV-1 basic leucine zipper factor (HBZ). In this study we found that HBZ activates al. (2019) HTLV-1 basic leucine zipper factor expression of Heme Oxygenase 1 (HMOX-1), a component of the oxidative stress response protects cells from oxidative stress by upregulating expression of Heme Oxygenase I. PLoS Pathog 15 that functions to detoxify free heme. Transcription of HMOX1 and other antioxidant genes is (6): e1007922. https://doi.org/10.1371/journal. regulated by the small Mafs.
  • MAF Proteins: a Family of Regulating and Regulated Molecules

    MAF Proteins: a Family of Regulating and Regulated Molecules

    Editorial Page 1 of 5 MAF proteins: a family of regulating and regulated molecules Maria Maddalena Simile, Gavinella Latte, Rosa Maria Pascale Department of Medical, Surgery and Experimental Sciences, University of Sassari, Sassari, Italy Correspondence to: Rosa Maria Pascale. Department of Medical, Surgery and Experimental Sciences, Division of Molecuolar Pathology, University of Sassari, Sassari, Italy. Email: [email protected]. Provenance: This is an invited Editorial commissioned by Guest Section Editor Kaiping Zhang (Academic Director, AME Publishing Company). Comment on: Liu T, Yang H, Fan W, et al. Mechanisms of MAFG dysregulation in cholestatic liver injury and development of liver cancer. Gastroenterology 2018;155:557-571.e14. Received: 19 October 2018; Accepted: 26 October 2018; Published: 16 November 2018. doi: 10.21037/dmr.2018.10.02 View this article at: http://dx.doi.org/10.21037/dmr.2018.10.02 The proteins of MAF family (the cellular counterpart In addition to the transcription regulators containing of viral oncogene MAF, isolated from avian bZip regions, Jun, Fos, and Bach1, and several other factors musculoaponeurotic fibrosarcoma) are transcription factors heterodimerize with v-/c-MAF proteins. The component regulating gene expression. On the bases of the size, they of the helix-loop-helix zipper transcription factors, USF2 are sub-grouped into two families: the “large” (L-MAFs: inhibits c-MAF. In turn, c-MAF forms with c-Myb a MAFA, MAFB, c-MAF, and Nrl) and the “small” (S-MAFs: transcriptionally inert complex, involved to guide the MAFF, MAFK, and MAFG) MAF proteins (1). development of myeloid cells lineage. Similarly, MAFB The MAFs are evolutionary conserved among represses the transcriptional activity of c-Ets-1, inhibiting vertebrates, and they are expressed in a wide range of erythroid cells differentiation (3).
  • FACS FACTS Newsletter in 2006

    FACS FACTS Newsletter in 2006

    Issue 2007-1 December 2007 FACS A C T S The Newsletter of the Formal Aspects of Computing Science (FACS) Specialist Group ISSN 0950-1231 FACS FACTS Issue 2007-1 December 2007 About FACS FACTS FACS FACTS [ISSN: 0950-1231] is the newsletter of the BCS Specialist Group on Formal Aspects of Computing Science (FACS). FACS FACTS is distributed in electronic form to all FACS members. Submissions to FACS FACTS are always welcome. Please visit the newsletter area of the FACS website [http://www.bcs-facs.org/newsletter] for further details. Back issues of FACS FACTS are available to download from: http://www.bcs-facs.org/newsletter/facsfactsarchive.html The FACS FACTS Team Newsletter Editor Margaret West [[email protected]] Editorial Team Jonathan Bowen, Paul Boca Contributors to this Issue Paul Boca, Jonathan Bowen, Tim Denvir. Margaret West 2 FACS FACTS Issue 2007-1 December 2007 The activities of FACS (e.g., sponsoring conferences and workshops, offering student bursaries and hosting evening seminars) are funded solely from membership subscriptions. The more paid-up FACS members we have, the more we can do. ☺ If you would like to become a FACS member – or renew your lapsed membership – please complete the membership form on Page 24 of this issue of FACS FACTS. If you have any questions about FACS, please send these to Paul Boca [[email protected]] From Margaret West: I am sorry for the rather sparse News Letter. I hope to make up for this next year! The next copy should include items omitted from this issue. Newsletter Editor, Algarve, Portugal, September 2007 3 FACS FACTS Issue 2007-1 December 2007 Editorial Jonathan Bowen, Chair, BCS-FACS Please accept our apologies for the long delay since the last edition of the FACS FACTS Newsletter in 2006.