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493 Subpart B—Food Additive Listing

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493 Subpart B—Food Additive Listing Food and Drug Administration, HHS § 573.160 Subpart B—Food Additive Listing kanr gene along with the genetic mate- rial of interest. § 573.120 Acrylamide-acrylic acid [59 FR 26711, May 23, 1994] resin. Acrylamide-acrylic acid resin § 573.140 Ammoniated cottonseed (hydrolized polyacrylamide), only for meal. the purposes of this section as de- The food additive ammoniated cot- scribed below, may be safely used in ac- tonseed meal may be safely used in ac- cordance with the following prescribed cordance with the following conditions: conditions: (a) The food additive is the product (a) The additive is produced by po- obtained by the treatment of cotton- lymerization of acrylamide with par- seed meal with anhydrous ammonia tial hydrolysis, or by copolymerization until a pressure of 50 pounds per square of acrylamide and acrylic acid with the inch gauge is reached. greater part of the polymer being com- (b) It is used or intended for use in posed of acrylamide units. the feed of ruminants as a source of protein and/or as a source of non- (b) The additive meets the following protein nitrogen in an amount not to specifications: exceed 20 percent of the total ration. (1) A minimum molecular weight of 3 (c) To assure safe use, the label and million. labeling of the additive and of any feed (2) Viscosity range: 3,000 to 6,000 cen- additive supplement, concentrate, or tipoises at 77 °F in a 1 percent aqueous premix prepared therefrom shall bear, solution as determined by LVF Brook- in addition to the other information re- field Viscometer or equivalent using a quired by the act, the following: number 6 spindle at 20 r.p.m. (1) The name of the additive. (3) Residual acrylamide: Not more (2) The maximum percentage of than 0.05 percent. equivalent crude protein from the non- (c) It is used as a thickener and sus- protein nitrogen. pending agent in nonmedicated aque- (3) Directions for use to provide not ous suspensions intended for addition more than 20 percent of the additive in to animal feeds. the total ration. (4) A statement: [41 FR 38652, Sept. 10, 1976, as amended at 45 (i) That not more than one-third of FR 38058, June 6, 1980] the total protein in the feed should come from nonprotein nitrogen § 573.130 Aminoglycoside 3′-phospho- transferase II. sources. (ii) That the additive is not to be The food additive aminoglycoside 3′- given to debilitated or starved animals. phosphotransferase II may be safely (iii) ‘‘Warning—This feed should be used in the development of genetically used only in accordance with directions modified cotton, oilseed rape, and to- furnished on the label.’’ matoes in accordance with the fol- lowing prescribed conditions: [41 FR 38652, Sept. 10, 1976, as amended at 42 FR 52397, Sept. 30, 1977] (a) The food additive is the enzyme aminoglycoside 3′-phosphotransferase § 573.160 Ammoniated rice hulls. II (CAS Reg. No. 58943–39–8) which cata- The food additive ammoniated rice lyzes the phosphorylation of certain hulls may be safely used in accordance aminoglycoside antibiotics, including with the following prescribed condi- kanamycin, neomycin, and gentamicin. tions: (b) Aminoglycoside 3′- (a) The food additive is the product phosphotransferase II is encoded by the obtained by the treatment of ground kanr gene originally isolated from rice hulls with monocalcium phosphate transposon Tn5 of the bacterium Esch- and anhydrous ammonia at a tempera- erichia coli. ture of 350 °F and a pressure of 175 (c) The level of the additive does not pounds per square inch. exceed the amount reasonably required (b) It is used or intended for use in for selection of plant cells carrying the the feed of beef cattle as a source of 493 VerDate Mar<15>2010 09:09 Aug 04, 2014 Jkt 232075 PO 00000 Frm 00503 Fmt 8010 Sfmt 8010 Y:\SGML\232075.XXX 232075 wreier-aviles on DSK5TPTVN1PROD with CFR.
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