2007 ANNUAL REPORT

IN SEARCH OF LASTING SOLUTIONS TO HIV/AIDS

THE FOUNDATION FOR AIDS RESEARCH amfAR, The Foundation f o r A i d S R e s e ar c h , i s dedicated to ending the global AIDS epidemic t h r o u g h i n n o v at i v e research.

Cover photos (from top): TREAT Community Programs Manager Jennifer I-Ching Ho holds an HIV-positive child (photo: Karl Grobl); Dr. Nolwenn Jouvenet, Aaron Diamond AIDS Research Center (photo: Dr. Rowena Johnston); Shan Grant, Miguel Rivera, and Robert Green (photo: Winnie McCroy). FROM THE CHAIRMAN 02 A Global Force Against a Global Epidemic

FROM THE CHIEF EXECUTIVE OFFICER 03 Good Research Drives Good Policy

PEOPLE LIVING WITH HIV/AIDS 04

MAJOR ACCOMPLISHMENTS 06 RESEARCH 08

GLOBAL INITIATIVES 15 PUBLIC POLICY 22

EDUCATION AND INFORMATION 26

GIVING 30 Individual Giving Institutional Giving In-Kind Contributions Planned Giving Volunteer Support Workplace Giving

FINANCIAL SUMMARY 44 From the Treasurer and the Chair of the Finance and Budget Committee Statement of Activities and Changes in Net Assets Statement of Financial Position

LEADERSHIP AND ADVISORY COMMITTEES 46

ACKNOWLEDGMENTS from the Chairman

A Global Force Against a Global EPIDEMIC

Of the 33 million people living with HIV/AIDS, more than 90 percent are in the develop- ing world. For most of its 23 years at the leading edge of the fight against AIDS, amfAR has brought AIDS research, prevention, and education to countries hard hit by the epidemic. A global health threat demands nothing less than a global response. A couple of years ago, we changed our name from the American Foundation for AIDS Research to The Foundation for AIDS Research to reflect the increasingly international scope of both the epidemic and amfAR’s work. The TREAT Asia Network that amfAR formed in 2001 is now a highly regarded of regional collaboration on HIV/AIDS research, education, and training across Asia and

amfAR Annual Report 2007 the Pacific. In 2007 we launched an important new international venture: the MSM Initiative. The first round of community awards that form the core of this initiative will support front-line organizations working to combat the rapid and deadly spread of HIV among men who have sex with men (MSM) in Africa, the Caribbean, and Southeast Asia. In 2008, additional awards will be made for innovative programs in Latin America and Asia and the Pacific. Here in the U.S., some of our own cities have rates of infection that rival parts of the developing world. In Washington, D.C., one in 20 residents is HIV positive. So we continue to fight for evidence-based policies that are essential to reducing infection rates 02 and for adequate levels of government funding for HIV/AIDS research, treatment, and From the Chairman prevention. The international growth of amfAR’s programs has been matched by a correspond- ing expansion in the fundraising arena. For many years, our successful Cinema Against AIDS series has raised funds and brought AIDS awareness to a global audience during the Cannes International Film Festival. In 2007 we were invited to bring the event to the Rome and film festivals. These new venues enable us to teach new audiences about the vital importance of AIDS research and to combat HIV-related stigma. Our fundraising efforts will be greatly assisted by the passion and dedication of Sharon Stone, who has taken on the role of global fundraising chairman. On the staff side, we are pleased that Kevin Frost, who ably served for many years as vice president for global initiatives, has accepted the position of chief executive officer. Kevin’s experi- ence, energy, and vision will help guide and drive amfAR as we expand our international initiatives while maintaining our fundamental commitment to AIDS research. As we embrace the challenges that confront us, we recognize that our work and accomplishments would not be possible without the continued support of generous individuals and organizations. Your ongoing commitment inspires us and enables us to quicken the pace of our efforts to end this deadly epidemic.

Kenneth Cole Chairman of the Board from the ChIEF EXECUTIVE OFFICER

Good Research Drives Good Policy

I like to think that amfAR has the mind of a scientist and the soul of an activist. For 23 years, we have pushed at the frontiers of AIDS research, investing in unexplored areas that have yielded new treatments, improved prevention methods, and vital clues to HIV eradication. And we have pushed for AIDS-related policies rooted in science, compas- sion, and common sense. Both advocacy and research require patience and persistence, and can take years to bear fruit. Studies that amfAR funded in 1995, for example, pointed the way to the development and approval in 2007 of the first medication in a brand new class of AIDS drugs. These so-called CCR5 blockers bring an important new option—and new hope— to patients developing resistance to currently available treatments. While past amfAR grants and fellowships continue to influence the discoveries of today, we launched a new initiative in 2007 that will help shore up the future of AIDS research. Young scientists are often those with the most ingenious ideas, but increas- ingly fierce competition for funds threatens to drive them away from research on AIDS. Our Mathilde Krim Fellowships in Basic Biomedical Research provide a critical source of amfAR Annual Report 2007 amfAR funds that will help nurture these AIDS research leaders of tomorrow. While substantial resources are quite rightly being invested in the delivery of treat- 03 ment to those who need it, there is a growing consensus that insufficient attention is being paid to research. That consensus was enshrined in the Sydney Declaration of 2007, which recommends that 10 percent of all HIV/AIDS funding be devoted to research. amfAR was among almost 2,000 signatories of the Declaration, which stressed that the necessary research should extend well beyond the laboratory. Basic science is essential, of course, but above all, research is about people, communities, and human behavior.

As the Sydney Declaration states, “good research drives good policy.” We couldn’t the Chief Executive Officer From agree more, since it is good policy that delivers the benefits of research to people. As scientists and activists, we shall continue to support the best AIDS research and the smartest AIDS policies until we bring this deadly epidemic to an end.

Kevin Robert Frost Chief Executive Officer PEOPLE LIVING WITH HIV/AIDS, 2007 amfAR Annual Report 2007

North America 1.3 million (480,000–1.9 million)

04 Caribbean People Living With HIV/AIDS 230,000 (210,000–270,000)

World at a Glance • 33.2 million people were living with HIV/AIDS in 2007. Latin America • 2.1 million of them were 1.6 million under the age of 15. (1.4–1.9 million) • 2.5 million people were estimated to be infected with HIV in 2007. • 420,000 were under the age of 15. • 6,800 people contract HIV every day—283 every hour. • 2.1 million people died from AIDS in 2007. • 290,000 of them were under the age of 15.

Source:Source: UNAIDSUNAIDS/World Health Organization Global Total: 33.2 million (30.6–36.1 million)

Eastern Europe & Central Asia Western & 1.6 million Central Europe (1.2–2.1 million) 760,000 (600,000–1.1 million) East Asia

800,000 Annual Report 2007 amfAR (620,000–960,000)

South & 05 Southeast Asia North Africa & 4 million Middle East (3.3–5.1 million) 380,000 (270,000–500,000) People Living With HIV/AIDS Living People

Sub-Saharan Africa 22.5 million (20.9–24.3 million) Oceania 75,000 (53,000–120,000)

The numbers indicated in parentheses define the boundaries within which the actual numbers lie, based on the best available information. Major ACCOMPLISHMENTS, 2007

Securing the Future of AIDS Research Advocacy Efforts Pay Off Funding sources for promising young scientists have become amfAR has been a leading advocate of the increased federal increasingly difficult to secure, yet these same young research- funding for AIDS research that is necessary to continue U.S. ers are often those with the most innovative ideas. To support leadership in cutting-edge discoveries related to the preven- these future leaders of AIDS research and to advance their tion, care, and treatment of HIV/AIDS. The Foundation’s efforts promising studies, in 2007 amfAR launched the Mathilde Krim contributed to a $619.5 million increase in the FY 2007 budget Fellowships in Basic Biomedical Research. Named for amfAR’s of the National Institutes of Health and an additional $330 founding chairman, the million increase in FY 2008. amfAR Annual Report 2007 Krim Fellowships moved from concept to funding in Syringe Exchange Funding Ban Overturned less than a year. In Washington, D.C., where one in 20 residents is living with HIV, the federal government long banned the city from using New HIV/AIDS local taxpayer dollars to fund syringe exchange programs— Drug Class a proven approach to HIV prevention. Since the ban was Gains Approval imposed, amfAR has provided grants to support syringe In August, the Food and exchange in the District and has been vocal and persistent in Drug Administration its opposition to the ban. In 2007, both the House and Senate 06 approved maraviroc, the finally removed the restrictive legislative language, an advocacy Major Accomplishments first in a new class of anti- triumph that was a decade in the making. HIV drugs called CCR5- blockers. amfAR played Stemming the Tide of AIDS Among Men a major role in spurring Who Have Sex with Men the early development of maraviroc through initial research Recent studies show surging rates of HIV infection among men by amfAR grantee Dr. Nathaniel Landau, who first described who have sex the vital role of CCR5 in HIV infection and the likelihood that with men (MSM) blocking it would not be detrimental to human health. A study in resource-limited showed that by simply adding maraviroc to existing combina- countries, where tion antiretroviral therapy, patients are twice as likely to attain discrimination undetectable virus levels. and denial of male-male sex Cutting-Edge Grants and Fellowships continue to fuel In 2007, amfAR awarded 18 research grants and fellowships the epidemic. in two cycles totaling more than $2.1 million. One round of In an effort to awards supported a range of projects aimed at increasing bolster prevention and treatment efforts and to combat stigma, understanding and prevention of rectal HIV transmission; the amfAR launched the MSM Initiative. The cornerstone of the second focused on research that would increase understanding Initiative is a community awards program that will funnel of the social and biological factors that influence, or undermine, urgently needed resources to grassroots groups in developing the effective treatment of HIV/AIDS. countries in support of their innovative HIV/AIDS programs that build on and extend the benefits of current research. Saving the Lives of Children in Asia funded investigators were published in leading peer-reviewed Close to 200,000 children are living with HIV/AIDS in Asia journals. These reports and their dissemination among the and it is estimated that only 20 percent of them are receiv- scientific community are essential for researchers to fit together ing the treatment and care they so desperately need. To help the pieces of the intricate AIDS puzzle. improve and extend life for these children, Educating Healthcare Providers amfAR’s TREAT Asia amfAR is one of a small group of AIDS organizations accredited Network launched a to provide continuing medical education to physicians and pediatrics initiative in other healthcare providers. In 2007, the Foundation presented 2006. The initiative a continuing medical education series in 10 U.S. cities address- involves 22 pediatric ing the needs of treatment-experienced patients. The series clinics, hospitals, and reached more than 550 health- research centers across care professionals, primarily Asia that are working nurse practitioners and physician collaboratively on HIV assistants with heavy HIV case

treatment and clinical loads. Two community forums Annual Report 2007 amfAR research. A pediatric on antiretroviral therapy were 07 HIV observational also conducted, along with eight database, established think tanks that examined gaps in 2007, is now pooling patient information that will help in HIV/AIDS education in the U.S. researchers find urgently needed answers to the optimal treat- and ways to fill them. ment of pediatric HIV. Charting the Worldwide Major Accomplishments Major Giant Steps for MSM in Asia Course of AIDS HIV infection rates are disproportionately high among MSM in In an effort to create a global database large enough to many parts of Asia. To fight collectively for regional HIV preven- address detailed questions about the worldwide course of HIV/ tion and treatment services for this long-ignored population, a AIDS, U.S. health authorities established an ambitious interna- consortium of more than 80 grassroots HIV organizations has tional collaboration known as the International Epidemiologic come together as the Purple Sky Network. Its activities across Databases to Evaluate AIDS. TREAT Asia was selected to a large swath of Southeast Asia are coordinated by TREAT Asia. manage the Asia/Pacific section of this project, which began its Thanks in part to the efforts of the Purple Sky Network, five out first year of operation in 2006. of the six countries in the Mekong region have adopted specific plans that address the HIV/AIDS needs of MSM. Tracking the Spread of Drug-Resistant HIV HIV drug resistance is perhaps the single greatest factor Expanding the HIV Knowledge Base influencing the long-term success of treatment scale-up efforts amfAR-funded research continues to generate a steady stream in Asia. In 2007, TREAT Asia began enrolling clinical studies of important new knowledge about HIV/AIDS. In 2007, more to monitor the development of HIV drug resistance in Asia. than 40 scientific papers authored or co-authored by amfAR- These studies will help to develop capacity for monitoring and surveillance of the spread of drug-resistant HIV in developing countries. RESEARCH

illions of people with HIV/AIDS are living longer, healthier lives as a direct result of AIDS research. The powerful anti-HIV drugs that are increasingly finding their way to even the most far-flung populationsM all had their genesis in the laboratory. Three of the AIDS drug classes in use today have their origins in amfAR-funded research. Similarly, AIDS research has helped prevent countless new HIV infections. In many parts of the developed world, for example, mother-to-child transmission of HIV has been all but eliminated. This is in large part due to the use of antiretroviral drugs to block mother-to-child transmission, a concept pioneered by amfAR-supported research in the early days of the epidemic. Today, amfAR continues to support pioneering studies in the timing of their establishment, in order to understand how areas that are not being adequately investigated by others. potential cures must work. Working on the frontiers of AIDS research, amfAR-funded scientists are attacking HIV from numerous angles. amfAR’s New AIDS Drug Has Roots in amfAR Research research strategy can be divided into three objectives: In 2007, the first in a new class of anti-HIV drugs became available to patients who are not responding to other AIDS • Ensuring that all people living with HIV reap the benefits of medications. Approved by the FDA in August, maraviroc acts past research accomplishments; by blocking HIV’s access to the CCR5 protein on the surface of RESEARCH • Addressing the current needs of vulnerable populations, susceptible cells. A study of more than 600 patients showed particularly in the area of HIV prevention; and that adding maraviroc to combination antiretroviral therapy • Searching for lasting solutions leading to an AIDS-free was twice as likely to result in undetectable virus levels. It was future. amfAR grantee Dr. Nathaniel Landau and others who, in the 1990s, identified the key role of CCR5 in HIV infection and Spreading the Benefits of AIDS Research: illuminated a path to developing a new drug class. Optimizing Treatment amfAR grantee Dr. Nancy Shulman of Stanford University Not everyone has benefited equally from the enormous and Palo Alto V.A. Medical Center has explored whether mara- advances in HIV/AIDS treatment of recent years. Biological viroc can also decrease the activation of the immune system, factors can influence responses to treatment, while social which may also help prevent disease. She said of her research, circumstances can hinder access to HIV testing and medical “If maraviroc can decrease HIV disease both by blocking HIV care. In June 2007, amfAR granted nearly $1.2 million for entry into cells as well as decreasing immune activation, this amfAR Annual Report 2007 amfAR 10 studies aimed at gaining a better understanding of these could have implications for broadening the use of maraviroc— impediments to optimal HIV treatment and care. even in patients who might otherwise seem to be unsuitable 09 Grantee Dr. Jennifer Sayles of the University of California, candidates for the drug.” Los Angeles, is studying the validity of a new measure of HIV-

related stigma in women, with the long-term goal of identify- Research ing factors that might guide future interventions to improve the quality of women’s healthcare. The number of women “Twenty-five years after the living with HIV is increasing, and around the world, women face stigma and even violence because of their HIV status. The first identification of AIDS, U.S. is no exception, according to a survey conducted by Harris Interactive for amfAR in 2007 (see page 29). Reducing stigma the taboos that surround an would dismantle a pervasive barrier to HIV testing, treatment, open discussion of sexual and care. Three of the new studies will assess the implications of behavior are still haunting changes in HIV testing recommendations adopted by the us in our efforts to contain Centers for Disease Control and Prevention (CDC) in 2007. In the face of stubbornly high infection rates in the U.S., the CDC this pandemic. It is time for now advises healthcare professionals to perform routine HIV screening of adults, adolescents, and pregnant women. us to take an honest and un- Other researchers will examine the influence of biologi- flinching look at how HIV is cal factors on treatment patterns. Dr. Stephen Kent of the University of Melbourne, , is studying HIV reservoirs, spread and how to minimize where the virus persists beyond the reach of the immune the risks.” system or antiretroviral therapy. He is examining the nature of

the virus strains that become part of these reservoirs, as well as “The Krim Fellowships are an excellent example of how The Krim Fellowships are a fitting tribute to the vision amfAR facilitates and unwavering commitment the entry of young to research of amfAR Founding Chairman scientists into the Dr. Mathilde Krim. field of AIDS research. They’ll be the leaders

amfAR Annual Report 2007 of tomorrow.” Rejuvenating the Field of AIDS Research

n January 2007, amfAR launched a new research initiative in honor of its founding chairman: The Mathilde Krim Fellowships in Basic Biomedical Research. The aim was to confront an urgent Understanding Rectal HIV problem. At a time when HIV/AIDS kills more than 2 million Transmission people each year, it has become increasingly difficult for bright “Twenty-five years after the first identification young scientists to secure funding for their innovative research of AIDS, the taboos that surround an open 10 projects. discussion of sexual behavior are still haunting Research The proportion of funding awarded to scientists aged 35 or younger has us in our efforts to contain this pandemic,” said Ideclined steadily from 23 percent in 1980 to below four percent in 2001, Dr. Rowena Johnston, amfAR’s vice president for according to a study by the National Institutes of Health. Meanwhile, the research. “It is time for us to take an honest and share of grants going to older scientists has increased sharply. The result is unflinching look at how HIV is spread and how that young scientists, looking for support for original ideas, are increasingly to minimize the risks.” forced to leave academia. Up until now, there have been few studies Addressing this gap and moving from concept to funding in less than a of the extent to which HIV is spread by anal year, the Krim Fellowships are designed to support bright young scientists’ intercourse—a gap in knowledge that has left biomedical research aimed at treating, preventing, and eradicating HIV/AIDS. both men and women vulnerable to infection. The program funds two years of postdoctoral research, with the possibility of Increased understanding of rectal transmission one additional year of research support during the first year in a tenure-track will play an important role in developing strate- position. gies to reach people who have previously been The first round of applications for the Krim Fellowships was reviewed overlooked in HIV prevention. In January 2007, in the fall of 2007. “We received many applications of extraordinarily high amfAR awarded eight grants and fellowships to- caliber from leading laboratories around the world,” said Dr. Rowena taling nearly $1 million for research that tackles Johnston, amfAR’s vice president of research. “The overwhelming response both the biological and social aspects of rectal to this program underscores the pressing funding needs of new researchers transmission in order to remove the barriers to as support has dried up from other sources.” understanding and preventing this widespread “The Krim Fellowships are an excellent example of how amfAR facilitates mode of transmission. the entry of young scientists into the field of AIDS research,” said Dr. Paul Bieniasz of the Aaron Diamond AIDS Research Center in . “They’ll Toward a Cure be the leaders of tomorrow.” The development of highly active antiretroviral therapy (HAART), which has extended and improved the lives of many people living with HIV, has been “elite controllers” may provide insight into slowing or even hailed as one of the great scientific achievements of the last stopping viral reproduction. 25 years. But the ultimate goal is to find ways to eradicate the virus from the body completely, and to free HIV patients from Expanding the HIV Knowledge Base the burden of taking medications—which can cause debilitat- An important indicator of the caliber and productivity of ing side effects—for the rest of their lives. amfAR-supported researchers is the quantity of studies amfAR-funded scientists are rising to the challenge. A published in peer-reviewed journals. In fiscal year 2007, more number of researchers who received grants under amfAR’s viral than 40 papers by amfAR grantees and fellows appeared in eradication initiative continued their important work in 2007, the scientific press, contributing a wealth of important new exploring potential methods of flushing out latent virus that is knowledge about HIV that can be exploited by the broader hidden beyond the reach of current antiretroviral therapy. research community.

• amfAR fellow Dr. Fedde Groot is studying the ways in which Defining Drug Targets HIV targets uninfected cells in the gastrointestinal (GI) tract Dr. Jacqueline Reeves of Monogram Biosciences and Dr. Oliver and how virus spread can be controlled by drugs or antibodies. Hartley of the University of Geneva studied the process of Since the degree of cell loss in the gastrointestinal tract may mutation by which HIV is able to evade containment by current largely determine the course of the disease, Dr. Groot’s findings drug therapies. There are two varieties of co-receptor that HIV may guide future efforts to reduce or prevent cell loss. uses to bind to a cell: CCR5 and CXCR4. CCR5 is the portal • In a similar vein, Dr. Martin Markowitz and his team at the that HIV uses in nearly all cases of initial HIV infection. But Aaron Diamond AIDS Research Center are exploring potential over time, particularly in the absence of anti-HIV treatment, the viral reservoirs in the GI tract, and have found that T-cell levels virus often evolves into a form that can use CXCR4. And this Annual Report 2007 amfAR in the intestinal tract remained below normal despite treat- mutated version usually signals a much more virulent disease. ment. These study results will help guide interventions aimed at Drs. Reeves, Hartley, and colleagues identified the intermediate 11 preventing the loss of, or replenishing, immune cells in the GI steps the virus progresses through in the switch from using

tract, which are killed early in infection. CCR5 to CXCR4. Their research, published in the Journal of Research • Dr. Steven Deeks of the University of California, San Fran- Virology, will help determine both the potential and the limita- cisco, is examining HIV-positive people whose immune systems tions of anti-HIV drugs that target the CCR5 co-receptor. have controlled the virus without treatment. Studying these Another amfAR grantee, Dr. Pantelis Poumbourios of the

Working with a group of amfAR-funded researchers in Australia, Dr. Ya-Lin Chiu identified a new group of immune cells that harbor HIV. Burnet Institute in Victoria, Australia, described in the Journal of capitalize on recent research findings and emerging areas of Biological Chemistry his exploration of HIV-cell fusion, a process study. In addition to one-year grants for senior researchers, targeted by one of the newest anti-HIV drugs, Fuzeon the Foundation funds two-year fellowships for postdoctoral (enfuvirtide). The new knowledge gained by Dr. Poumbourios scientists working with an established mentor. The Founda- and his research group may facilitate the discovery of new tion’s support of early-stage and sometimes high-risk projects drugs to block the fusion process, and thus the formation of is a proven investment: for every dollar scientists receive from infectious virus. amfAR, they receive an average of $12 in subsequent funding from other sources. Identifying Roadblocks to a Cure amfAR grantee Dr. Suzanne Crowe of the Burnet Institute in A Relentless Pursuit of Prevention, Treatment, Melbourne, Australia, worked with amfAR fellows Dr. Ya-Lin and Cure Chiu and Dr. Secondo Sonza to identify a new group of immune In the months and years ahead, amfAR will continue to make

amfAR Annual Report 2007 cells that harbor HIV. They found that, in addition to CD4+ judicious investments in the research that is essential for the cells, a small subset of immune cells known as monocytes also ultimate conquest of AIDS. Preventing all new HIV infections harbor HIV during HAART. The group found that these cells calls for contributions from every area of HIV/AIDS research. may represent a continuing source of viral persistence, even Progress towards designing an AIDS vaccine or microbicide, in individuals with viral loads suppressed below detectable for example, is being made by biomedical researchers, while limits for prolonged periods of time, and could therefore limit social and behavioral scientists seek to understand the social the potential for a cure. Their findings, which appeared in the and psychological factors that can affect the adoption of HIV Journal of Immunology, support the necessity of pursuing all prevention and risk reduction behaviors. Unlike other funders possible concepts for curing HIV/AIDS, for people at all stages of HIV/AIDS research, amfAR aims to integrate these facets of 12 of the disease. research in the drive to ensure not only that new prevention Research and treatment interventions are discovered but also that they Minor HIV Genes are successfully put into practice. The amfAR-funded lab of Dr. Nathaniel Landau and amfAR- The often debilitating side effects of current AIDS drugs and supported fellow Dr. Lei Fang researched two accessory or the inexorable spread of drug-resistant strains of HIV demand “minor” genes of HIV, Vif and Vpr. Writing in Virology and the continual pursuit of new treatments. amfAR-funded Proceedings of the National Academy of Sciences, the research team scientists will continue to search for new angles from which described their work, which could point the way to new targets to attack the virus. Our brightest hope for the future, however, for anti-HIV drug development. lies in understanding the mechanisms by which HIV evades not only the vigorous immune response mounted by those who HIV and the Brain are infected, but also the very potent drugs that constitute the amfAR-funded scientist Dr. Beau Ances studied the changes current arsenal of anti-HIV therapy. A clearer understanding of in mental function associated with HIV infection and the these mechanisms will help create the roadmap to a cure. impact of HAART on cognitive function. Despite a decline in the incidence of HIV-related dementia due to increased use of HAART, it appears that some patients still experience cognitive problems. Writing in Archives of Neurology, Dr. Ances and his team described the new, more sensitive test they created to measure HIV’s effects on the brain.

Securing the Future of AIDS Research With the help of its Scientific Advisory Committee and other independent HIV/AIDS experts who volunteer to take part in the peer-review selection process, amfAR moves quickly to 2007 RESEARCH GRANTS AND AWARDS Impact of PD-1 on the establish- Vif:APOBEC3G: assay and structure ment and maintenance of the HIV-1 Nathaniel Landau, Ph.D. All projects listed below were supported by amfAR during the period reservoir Salk Institute for Biological Studies October 1, 2006, to September 30, 2007. Grants funded during fiscal Elias Haddad, Ph.D. La Jolla, CA Université de Montréal, Centre de $90,000 (2004) year 2007 but awarded in previous years are shown with the year of Recherche du CHUM the award in parentheses. Montréal, Canada Antibody mimetic inhibitors $107,568 of HIV fusion Richard Roberts, Ph.D. Establishment of the HIV reservoir California Institute of Technology during acute infection Pasadena, CA Research Grants HIV-1 infection of mucosal Stephen Kent, M.D. $86,302 (2004) lymphocytes and tissue explants University of Melbourne Preventing HIV Transmission Benjamin K. Chen, M.D., Ph.D. Melbourne, Australia Mount Sinai School of Medicine $120,000 Pursuing HIV Eradication Development of a standard rectal New York, NY microbicide delivery device $90,000 (2006) How to test: policy and practice after Genetic screens for inhibitors of HIV Alex Carballo-Diéguez, Ph.D. the CDC recommendations latency Research Foundation for Mental Interaction of HIV with the macaque Lori Leonard, Sc.D. Paul Bieniasz, Ph.D. Hygiene, Inc. female genital tract Johns Hopkins School of Public Health Aaron Diamond AIDS Research Center New York, NY Thomas J. Hope, Ph.D. Baltimore, MD New York, NY $119,992 Northwestern University $120,000 $120,000 (2006) Chicago, IL Colorectal explants to study HIV $90,000 (2006) CDC HIV testing guidelines: unresolved HIV controllers: a potential model for transmission and microbicides ethical concerns HIV eradication Charlene Dezzutti, Ph.D. Viral transmission and replicative Roland Merchant, M.D., Sc.D. Steven Deeks, M.D. Magee-Womens Research Institute fitness Rhode Island Hospital University of California, San Francisco and Foundation Dale McPhee, Ph.D. Providence, RI San Francisco, CA Pittsburgh, PA St Vincent’s Institute $120,000 $120,000 (2006) Fitzroy, Australia $120,000 Annual Report 2007 amfAR $90,000 (2006) AHI awareness and entry into care The role of CCR7 ligands and dendritic Epithelial injury and HIV penetration among high risk populations cells in latent HIV infection Female genital ulcer as a portal of 13 after simulated ejaculation Robert Remien, Ph.D. Sharon Lewin, F.R.A.C.P., Ph.D. Craig Hendrix, M.D. HIV entry Research Foundation for Mental Monash University Johns Hopkins University School of Eva Rakasz, Ph.D. Hygiene, Inc. Melbourne, Australia Medicine University of Wisconsin–Madison New York, NY $120,000 (2006) Research Baltimore, MD Madison, WI $119,654 $120,000 $90,000 (2006) Reservoirs of SIV in long-term The impact of stigma on access to HIV nonprogressors in rhesus macaques Mediation effect of network function Understanding the properties of treatment and care Binhua Ling, M.D., Ph.D. on HIV risk behavior among Chinese transmitted HIV-1 variants Jennifer Sayles, M.D. Tulane National Primate Research Hongjie Liu, Ph.D. Manish Sagar, M.D. University of California, Los Angeles, Center School of Medicine, Virginia Brigham and Women’s Hospital/ David Geffen School of Medicine Covington, LA Commonwealth University Harvard Medical School Los Angeles, CA $120,000 (2006) Richmond, VA Boston, MA $120,000 $119,988 $90,000 (2006) The GI tract may be a reservoir of Immunologic benefits of CCR5 ongoing viral replication during HAART Anal sex practices in high-risk South Amphibian derived microbicides that inhibitor intensification Martin Markowitz, M.D. African women and men inhibit HIV infection Nancy Shulman, M.D. Aaron Diamond AIDS Research Center Joanne Mantell, Ph.D. Derya Unutmaz, M.D. Palo Alto Veterans Administration New York, NY Research Foundation for Mental Vanderbilt University Medical School Medical Center and $120,000 (2006) Hygiene, Inc. Nashville, TN Stanford University New York, NY $90,000 (2005) Palo Alto, California Role of lymph node dendritic cells in $119,946 $107,644 HIV infection David McDonald, Ph.D. Rectal transmission of HIV-1 in a novel Optimizing HIV Treatment Evolutionary screen to identify novel Case Western Reserve University mouse model TRIM restriction factors Cleveland, OH Roberto Speck, M.D. Recent changes in HIV testing recom- Harmit Malik, Ph.D. $120,000 (2006) Division of Infectious Diseases, mendations: impact on youth at risk Fred Hutchinson Cancer Research Department of Internal Medicine, Marya Gwadz, Ph.D. Center Identifying the major tissue reservoirs University Hospital of Zurich NDRI USA, Inc. Seattle, WA in SIV/SHIV infected macaques Zurich, New York, NY $90,000 (2005) Bapi Pahar, Ph.D. $119,822 $119,598 Tulane National Primate Research Center Covington, LA $120,000 (2006) Effects of valproic acid therapy on gut Viral persistance in the MGT of RT- Relative fitness of early and late Identification of novel host factors mucosal HIV reservoirs SHIV infected macaques on HAART variants of SIV in vitro for HIV replication Jean-Pierre Routy, M.D. Miranda Xhilaga, Ph.D. Yegor Voronin, Ph.D. Lei Fang, M.D., Ph.D. McGill University Health Centre Mentor: Sharon Lewin, F.R.A.C.P., Ph.D. Mentor: Michael Emermann, Ph.D. Mentor: Nathaniel Landau, Ph.D. Montréal, Canada Monash University Fred Hutchinson Cancer Research The Salk Institute for Biological $119,827 (2006) Melbourne, Australia Center Studies $125,000 Seattle, WA La Jolla, CA $99,000 (2004) $99,000 (2005) Research Fellowships Molecular mechanisms of the HIV-1 coreceptor CCR5 function Characterization of HIV env variants Gabriel Birrane, Ph.D. Pursuing HIV Eradication that persist during HAART Preventing HIV Transmission Mentor: John Ladias, M.D. Patrick Harrington, Ph.D. Beth Deaconess Medical Center Quantitative fMRI of CNS-T ART on Mentor: Ronald Swanstrom, Ph.D. Colorectal responses to HIV-1 and Boston, MA HIV brain reservoirs University of North Carolina at modulation by microbicides $99,000 (2006) Beau Ances, M.D., Ph.D. Chapel Hill Carolina Herrera, Ph.D. Mentor: Ronald Ellis, M.D., Ph.D. Chapel Hill, NC Mentor: Robin Shattock, Ph.D. Designing inducible Pol II systems for University of California San Diego $99,000 (2005) St George’s University of London RNA interference of HIV-1 San Diego, CA

amfAR Annual Report 2007 London, United Kingdom Hoshang Unwalla, Ph.D. $125,000 (2006) Kinetics of HIV reactivation in latently $125,000 Mentor: John Rossi, Ph.D. infected T cells Beckman Research Institute of the City HIV-1 cell-cell spread in viral Young Kyeung Kim, Ph.D. Anal intercourse, STIs and HIV among of Hope dissemination and persistence Mentor: Jonathan Karn, Ph.D. STD clinic clients Duarte, CA Fedde Groot, M.Sc. Case Western Reserve University Marjan Javanbakht, Ph.D. $99,000 (2006) Mentor: Quentin Sattentau, Ph.D. Cleveland, OH Mentor: Peter Anton, M.D. The Sir William Dunn School of $99,000 (2005) University of California, Los Angeles The APOBEC3G-Vif interaction as a Pathology, University of Oxford Los Angeles, CA new HIV therapeutic target Oxford, United Kingdom Human cellular factors that restrict $112,193 Hendrik Huthoff, Ph.D. $124,882 (2006) HIV infection Mentor: Michael Malim, D.Phil. Susana Valente, Ph.D. HIV mucosal transmission in King’s College London Virologic correlates of subtype-A HIV Mentor: Stephen Goff, Ph.D. humanized mice model London, United Kingdom transmission in the City of 14 Liguo Zhang, Ph.D. $99,000 (2005) Richard Haaland, Ph.D. New York Mentor: Lishan Su, Ph.D. Mentor: Eric Hunter, Ph.D. New York, NY Research University of North Carolina at Mechanistic study of retroviral entry Emory University $99,000 (2005) Chapel Hill and restriction in vitro Atlanta, GA Chapel Hill, NC Virginie Sandrin, Ph.D. $99,000 (2006) $99,000 (2006) Mentor: Wesley Sundquist, Ph.D. Research Awards University of Utah Role of Tat methylation in HIV latency Harnessing RNA interference as an Salt Lake City, UT Sara Pagans, Ph.D. New York HIV research centers HIV microbicide $99,000 (2005) Mentor: Melanie Ott, M.D. consortium meeting Deborah Palliser, Ph.D. The J. David Gladstone Institutes Sherry Deren, Ph.D. Mentor: Judy Lieberman, M.D., Ph.D. Mechanism of postentry restriction of San Francisco, CA National Development and Research CBR Institute for Biomedical Research HIV-1 by TRIM5alpha $125,000 (2006) Institutions, Inc Boston, MA Chisu Song, Ph.D. New York, NY $99,000 (2005) Mentor: Christopher Aiken, Ph.D. Macrophage matrix metalloprotein- $5,000 Vanderbilt University School of ases role in persistence of HIV-1 in Structure based design of gp41 Medicine CNS 2008 Rectal Microbicide Satellite analogs for HIV1 vaccines Nashville, TN Nicole Webster, Ph.D. Meeting Florence Brunel, Ph.D. $99,000 (2005) Mentor: Suzanne Crowe, M.D. Ian McGowan, M.D., Ph.D. Mentor: Philip Dawson, Ph.D. Macfarlane Burnet Institute for Magee-Womens Research Institute Scripps Research Institute Negative regulation of HIV-1 cellular Medical Research and Public Health and Foundation La Jolla, CA co-factor P-TEFb Melbourne, Australia Pittsburgh, PA $99,000 (2004) Matjaz Barboric, Ph.D. $125,000 (2006) $25,000 Mentor: Matija Peterlin, M.D. University of California, San Francisco HIV reservoir in central memory T cells Optimizing HIV Treatment San Francisco, CA Nicolas Chomont, Ph.D. $99,000 (2004) Mentor: Rafick-Pierre Sekaly, Ph.D. Impulsivity, drug abuse, and HIV Université de Montréal medication adherence: An fMRI study HIV-1 envelope-gag interactions and Centre de Recherches du CHUM Christina Meade, Ph.D. assembly in lipid rafts Montréal, Canada Mentor: Steven Safren, Ph.D. Jayanta Bhattacharya, Ph.D. $83,100 (2005) Harvard Medical School–McLean Mentor: Ramesh Paranjape, Ph.D. Hospital/Massachusetts General National AIDS Research Institute Hospital Pune, India Belmont, MA $9,000 (2004) $124,000 GLOBAL INITIATIVES

he widespread availability of antiretroviral drugs has transformed HIV/AIDS for many into a manageable condition—at least in the developed world. But in resource-limited regions, economic constraints, limited healthcare infrastructure, stigma, discrimination, and gender inequality combine to fuel the spread of the epidemic and prevent people with HIV/AIDST from getting the help they need. More than 90 percent of the 33.2 million people with HIV/AIDS live in developing countries, and most do not know they are infected. Over the past two decades, amfAR has steadily expanded its international reach through carefully targeted research, prevention, education, and training initiatives in resource- limited countries. The MSM Initiative works in partnership with activists such as Dr. Steave Nemande

amfAR Annual Report 2007 (left), president of Alternatives- Cameroun, an organization working on MSM and HIV/AIDS issues in Douala, Cameroon, and Dr. Paul Semugoma (right), a physician in Kampala, Uganda.

The MSM Initiative • To advocate for effective policies and increased funding for 16 Around the world, men who have sex with men (MSM) suffer HIV programs for MSM. Global Initiatives disproportionately high rates of HIV infection. It is estimated that fewer than one in 20 MSM has access to HIV prevention, The cornerstone of the MSM Initiative is a community treatment, care, and services. “MSM have been largely ignored awards program through which amfAR supports the efforts by both social and public health structures in many countries of grassroots groups in developing countries to provide HIV for too long,” stated a recently published study in the journal prevention, treatment, care, and support services to MSM. PLoS Medicine. Looking at HIV prevalence rates in 38 low- and Targeting MSM organizations and networks in Africa, the middle-income countries, the study found that on average Caribbean, and Southeast Asia, an initial request for proposals MSM had a 19.3 times greater chance of being infected than elicited more than 120 applications—85 from Africa alone— the general population. and underscored the enormity of the unmet need. A second Laws against male-male sex exist in 85 countries around request for proposals will target groups working in Central and the world. Even in countries without legal prohibitions against South America and in Asia and the Pacific, and awards will be same-sex behavior, pervasive stigma often prevents MSM announced in 2008. from accessing HIV/AIDS prevention services or care. Without The community awards are complemented by advocacy appropriate health messages and support, many MSM in these activities, which aim to increase levels of support from govern- countries unknowingly engage in behavior that increases ments and nongovernmental institutions for prevention, treat- their risk of HIV infection. It is small wonder, then, that HIV ment, and support services for MSM. They will also advance prevalence among MSM is as high as 40 percent in Kenya, 27 domestic and international policy efforts to end the stigma, percent in Ukraine, and 21 percent in Uruguay. discrimination, and violence that threaten the lives of MSM and It is against this backdrop that amfAR launched the MSM fuel the spread of HIV/AIDS. Initiative in 2007. The Initiative has three primary goals: amfAR’s partners in the MSM Initiative are the United Na- tions Joint Programme on HIV/AIDS (UNAIDS) and the Global • To support and empower grassroots MSM organizations; Forum on MSM and HIV. The Initiative is supported by generous • To build understanding and awareness of HIV epidemics grants from the AIDS Foundation, the Elton among MSM; and John AIDS Foundation, GlaxoSmithKline’s Positive Fighting Pediatric AIDS: It Takes a Village Action programme, and the M•A•C AIDS Fund. or almost 200,000 children living with HIV/AIDS in Asia, survival TREAT Asia depends on much more than medication. Family and community In the Asia-Pacific region, approximately 4.8 support are as important as sophisticated medical care, and million people are living with HIV and 432,000 without access to education, nutrition, transportation, and other became newly infected in 2007. In anticipation necessities, the prognosis for HIV-positive children remains dire. of escalating rates of infection and a potentially Dr. Pagakrong Lumbiganon has been treating HIV-positive devastating epidemic, in 2001 amfAR launched children at ’s Srinagarind Hospital, a TREAT Asia site, for Therapeutics Research, Education, and AIDS Fmore than a decade and every day she sees the limits of what doctors can achieve. Training in Asia—TREAT Asia. This network of “As physicians,” she says, “we can only provide maybe 20 percent of what children hospitals, clinics, and research institutions now need. With children, HIV infection is not treated just by pills. Children need the care includes 20 adult and 22 pediatric sites in 14 of family, they have to have friends, they have to go to school. It’s not just medical countries. TREAT Asia works with civil society to care.” ensure the safe and effective delivery of HIV treat- The importance of a network of care is an article of faith among HIV/AIDS ment across the Asia-Pacific region, to provide pediatricians. As TREAT Asia steering committee member Dr. Annette Sohn stated at treatment and prevention education to healthcare the network’s September 2007 meeting, “The quality of the collaborative relation- providers and the HIV/AIDS community, and to ship between the caretaker and the child will determine the success of treatment.” conduct clinical research specific to patient Across Asia, government funding for HIV/AIDS pediatric treatment rarely covers populations in the region. support services of any kind. But some TREAT Asia-affiliated pediatric programs

have been able to contrive a variety of innovative strategies to help them offer a Annual Report 2007 amfAR Improving Treatment and Care for Children broader range of services. Close to 200,000 children are living with HIV/ Dr. Pagakrong’s pediatric HIV/AIDS team at Srinagarind Hospital has looked out- 17 AIDS in Asia and it is estimated that only 20 side its own walls for help, gradually establishing relationships with multiple NGOs, percent of them are receiving the treatment and each of which supports a different aspect of social and family services. care they so desperately need. Since most clinical But in spite of her successes, Dr. Pagakrong worries about what will happen to research has focused on the treatment of adults, her young patients as they come into adulthood. Shaking her head firmly, she says, Global Initiatives “We have to do more.”

“The pediatrics network is unique in that it is made up of clinicians who are on the front lines of pediatric HIV treatment and clinical research The pediatric HIV/AIDS team at Srinagarind Hospital in Thailand has been able to contrive in Asia.” innovative strategies to help them offer a broader range of services for HIV-positive children. little is known about the proper treatment of children with HIV. generated a range of useful information for researchers and Pediatricians must grapple with complex questions, such as physicians across Asia. In 2007 alone, seven reports on treat- when to initiate treatment, which drugs to use and at which ment patterns and co-infections were published in prestigious dosages, and when to switch regimens to avoid side effects peer-reviewed journals including The Journal of Acquired Immune or treatment failure. Children face their own psychosocial Deficiency Syndrome, HIV Medicine, and Clinical Infectious Diseases. issues, and require care that extends well beyond antiretroviral An important component of the pediatrics initiative is a therapy. pediatric HIV observational database that was established in To help improve treatment, care, and quality of life for 2007 and is now pooling vital information on the epidemiol- children living with HIV/AIDS across Asia, a pediatrics initiative ogy of pediatric HIV in Asia, disease patterns, and treatment was launched alongside the TREAT Asia network in 2006. The outcomes. The information gathered and analyzed will help initiative’s goals are to: researchers find urgently needed answers to the optimal treatment of pediatric HIV. • Conduct research that is specific and responsive to the TREAT Asia also manages the Asia-Pacific section of the amfAR Annual Report 2007 needs of HIV-positive children in the region; International Epidemiologic Databases to Evaluate AIDS • Educate and train healthcare professionals in pediatric (IeDEA), a collaboration established by the U.S. National Insti- treatment and care; tute of Allergy and Infectious Diseases that began its first year • Undertake communications and policy activities that ad- of operation in 2006. The aim of this ambitious initiative is to dress issues surrounding pediatric treatment and care; and create a global database large enough for detailed study of • Strengthen civil society’s understanding of pediatric HIV/ the spread of HIV infection worldwide and to identify trends in AIDS and its capacity for the safe and effective treatment of the use and efficacy of treatments in different regions. TREAT children with the virus. Asia is contributing anonymous data to IeDEA from more than 18 6,000 patients at 44 clinical centers in the Asia-Pacific region, Global Initiatives The pediatrics initiative coordinates the efforts and pools including Australia. the resources of healthcare professionals and researchers at Drug resistance represents a significant long-term threat to 22 sites in Australia, Cambodia, China, India, Indonesia, Laos, the efficacy of antiretroviral therapy. The TREAT Asia Studies Malaysia, Thailand, and Vietnam. The network represents a to Evaluate Resistance (TASER) are a collaborative effort by combined caseload of more than 4,300 children with HIV. TREAT Asia and the PharmAccess Foundation of the Nether- “The pediatrics network is unique in that it is made up of lands to monitor the emergence and transmission of HIV drug clinicians who are on the front lines of pediatric HIV treat- resistance in Asia and Africa. ment and clinical research in Asia,” said Dr. Annette Sohn, a representative of the pediatrics initiative on the TREAT Asia Help for MSM Steering Committee. “Some of us have had years of experi- TREAT Asia lies at the center of efforts to stem the rising tide ence with antiretroviral treatment, while others lack access to of HIV among men who have sex with men in Southeast Asia. these drugs, but all of us are committed to providing care and In 2006 it was selected as regional coordination secretariat for treatment to children with HIV. By coming together, we have Purple Sky, a network of more than 80 organizations working an opportunity to develop our regional capacity to conduct to improve prevention, treatment, and care for MSM in the multinational research and share clinical expertise.” Greater Mekong Sub-Region, which encompasses Cambo- dia, China’s Yunnan and Guangxi provinces, Laos, Myanmar, Tracking the Epidemic Thailand, and Vietnam. Collecting accurate data on patterns of HIV disease, demo- Purple Sky was organized in 2006, and by the fall of graphics, modes of transmission, and treatment outcomes is 2007 its advocacy efforts had already made a difference. The essential to developing and implementing effective treatment network was instrumental in convincing the governments of and prevention strategies for the region. The TREAT Asia HIV Cambodia, China, and Laos to add MSM-specific interventions Observational Database (TAHOD), the region’s first such to their national strategic plans on HIV/AIDS. database for HIV/AIDS, houses anonymous data from more “This is a huge change,” said Clif Cortez, a member of the than 3,800 patients at 17 sites. The database has already Purple Sky Network’s advisory board and USAID’s Bangkok Jennifer I-Ching Ho, manager of TREAT Asia’s community programs, holds an HIV-positive child during a site visit in China.

regional senior advisor. “Prior to the work of the Purple Sky Inspiring Young Activists

Network, none of the national governments in this region were The Asian Community for AIDS Treatment and Advocacy Annual Report 2007 amfAR anywhere near being at the table as partners on MSM and (ACATA) is a TREAT Asia mentoring program initiated in 19 HIV.” 2005 with support from GlaxoSmithKline’s Positive Action programme. ACATA has brought young treatment advocates Education and Training together from around the region to increase their knowledge Providing education and training for physicians and other of HIV/AIDS, build their advocacy skills, share experiences, and healthcare professionals is essential to improving HIV treat- connect them to the medical and scientific communities. Most Global Initiatives ment and care. Since its inception, TREAT Asia has sponsored ACATA members have reached the end of their three-year and conducted workshops and training sessions in many training cycle and are considering future projects they may countries in the region. undertake together. In Cambodia, TREAT Asia supports several components of the National HIV Care Training program. It provides training Responding to an Epidemic Without Borders for new opportunistic infection/antiretroviral therapy teams at As the world grows smaller through increased travel and district hospitals, support and mentoring visits to new and migration, preventing the spread of infectious diseases such existing teams, regional workshops for the teams, and an as HIV/AIDS becomes ever more urgent. A successful global annual national symposium on care and treatment. response to the pandemic must respond to the needs of people During 2007, TREAT Asia also supported a range of com- at the local level, strengthen national treatment and preven- munity education and training programs, notably in Cambodia, tion efforts, and foster regional cooperation. Such a response China, Thailand, and Vietnam. In addition to establishing Red involves listening to many voices, including national govern- Ribbon Centers through local partnerships in China, which ments, the medical and scientific communities, grassroots provide highly effective treatment support and education for organizations, and individuals in marginalized groups such people affected by HIV/AIDS, TREAT Asia implemented a treat- as sex workers, injection drug users, and MSM. Through its ment literacy training program for women in Cambodia, helped international initiatives and collaborations, amfAR will continue create treatment literature with the Thai AIDS Treatment Action to invest in carefully targeted programs with the greatest Group, and initiated training for peer treatment educators in potential for extending and improving lives among the world’s 10 Vietnamese provinces. It also co-facilitated workshops on most vulnerable populations. antiretroviral treatment for Cambodian women. 2007 GLOBAL INITIATIVES GRANTS AND AWARDS Thira Sirisanthana, M.D. Australia HIV Observational Chiang Mai University Database All projects listed below were supported by amfAR during the period Chiang Mai, Thailand October 1, 2006, to September 30, 2007. Grants funded during $15,000 (Year 1 Subaward) Debra Allen, M.B.Ch.B., Dip Med $15,000 (Year 2 Subaward) Northern Sydney Central Coast Area fiscal year 2007 but awarded in previous years are shown with the Health Services, Holden Street Clinic year of the award in parentheses. Somnuek Sungkanuparph, M.D. Gosford, Australia Ramathibodi Hospital $2,925 (Year 1 Subaward) Mahidol University $1,725 (Year 2 Subaward) Bangkok, Thailand Asia Pacific HIV Observational Tuti Parwati Merati, M.D. $15,000 (Year 1 Subaward) Dr. Jonathan Anderson Database Udayana University School of $15,000 (Year 2 Subaward) Carlton Clinic Medicine Carlton, Australia Denpasar, Indonesia Matthew G. Law, Ph.D. Jun Yong Choi, M.D., Ph.D. $7,500 (Year 1 Program Technical $15,000 (Year 1 Subaward) National Centre in HIV Epidemiology Yonsei University College of Medicine Support Agreement) $15,000 (Year 2 Subaward) and Clinical Research Seoul, South Korea $7,500 (Year 2 Program Technical University of New South Wales $15,000 (Year 2 Subaward) Support Agreement) Shinichi Oka, M.D. Sydney, Australia International Medical Center of Japan $157,465 (2006–Year 1 Subaward) David Baker, B.H.B.

amfAR Annual Report 2007 Shinjuku-ku, Japan $19,904 (2006–Bridge Funding TREAT Asia Pediatric HIV 407 Doctors Pty., Ltd. $15,000 (Year 1 Subaward) Grant) Observational Database Sydney, Australia $15,000 (Year 2 Subaward) $239,069 (Year 2 Subaward) $7,500 (Year 1 Program Technical Matthew G. Law, Ph.D. Support Agreement) Adeeba Kamarulzaman, M.B.B.S., National Centre in HIV Epidemiology $7,500 (Year 2 Program Technical F.R.A.C.P. TREAT Asia HIV Observational and Clinical Research Support Agreement) University of Malaya Database University of New South Wales Kuala Lumpur, Malaysia Sydney, Australia Mark Bloch, M.D. $15,000 (Year 1 Subaward) Vonthanak Saphonn, M.D., Ph.D. $172,800 Holdsworth House Medical Practice $15,000 (Year 2 Subaward) National Center for HIV/AIDS, Sydney, Australia Dermatology & STDs / Cambodia Nagalingeswaran Kumarasamy, M.D., $7,500 (Year 1 Program Technical Christopher Lee, M.B.B.S., M.R.C.P. National Institute of Public Health M.B.B.S., Ph.D. Support Agreement) Sungai Buloh Hospital Phnom Penh, Cambodia YRG Center for AIDS Research and $7,500 (Year 2 Program Technical Sungai Buloh, Malaysia $15,000 (Year 1 Subaward) Education, VHS Support Agreement) 20 $15,000 (Year 1 Subaward)

Global Initiatives $15,000 (Year 2 Subaward) Chennai, India $15,000 (Year 2 Subaward) $15,000 Dr. Katherine Brown Yi-Ming Chen, M.D., Sc.D. South East Sydney Illawarra Area Goa Tau, Master Medicine National Yang-Ming University Pagakrong Lumbiganon, M.D. Health Service Port Moresby General Hospital Taipei, China Khon Kaen University Wollongong, Australia Port Moresby, Papua New Guinea $15,000 (Year 1 Subaward) Khon Kaen, Thailand $1,050 (Year 1 Subaward) $15,000 (Year 1 Subaward) $15,000 (Year 2 Subaward) $15,000 $1,725 (Year 2 Subaward) $15,000 (Year 2 Subaward) Fujie Zhang, M.D. Thanyawee Puthanakit, M.D. Andrew Carr, M.D. Rossana Ditangco, M.D. Beijing Ditan Hospital HIV-NAT/Thai Red Cross AIDS Research St. Vincent’s Hospital Sydney, Ltd. Research Institute for Tropical Beijing, China Centre Darlinghurst, Australia Medicine $15,000 (Year 1 Subaward) Bangkok, Thailand $7,500 (Year 1 Subaward) Muntinlupa City, Philippines $15,000 (Year 2 Subaward) $7,500 $7,500 (Year 2 Subaward) $15,000 (Year 1 Subaward) $15,000 (Year 2 Subaward) Patrick Li, M.B.B.S. Virat Sirisanthana, M.D. John Chuah, M.B.B.S., B.Sc. Queen Elizabeth Hospital Chiang Mai University Gold Coast Health Service District Poh-Lian Lim, M.D., M.P.H. Hong Kong, China Research Institute for Health Sciences Miami, Australia Tan Tock Seng Hospital $15,000 (Year 1 Subaward) Chiang Mai, Thailand $7,500 (Year 1 Subaward) Singapore $15,000 (Year 2 Subaward) $15,000 $7,500 (Year 2 Subaward) $15,000 (Year 1 Subaward) $15,000 (Year 2 Subaward) Nagalingeswaran Kumarasamy, M.D., Kulkanya Chokephaibulkit, M.D. Basil Donavon, M.B.B.S. M.B.B.S., Ph.D. Siriraj Hospital Mahidol Univeristy Sydney Sexual Health Centre Praphan Phanupak, M.D., Ph.D. YRG Centre for AIDS Research and Bangkok, Thailand Sydney Hospital HIV-NAT/Thai Red Cross Research Education,VHS $15,000 Sydney, Australia Center Chennai, India $5,025 (Year 1 Subaward) Bangkok, Thailand $15,000 (Year 1 Subaward) $3,525 (Year 2 Subaward) $15,000 (Year 1 Subaward) $15,000 (Year 2 Subaward) $15,000 (Year 2 Subaward) William Donohue, M.B.B.S. Sanjay Pujari, M.D. University of Adelaide Institute of Infectious Diseases Care and Prevention Program Pune, India Adelaide, Australia $15,000 (Year 1 Subaward) $2,250 (Year 1 Subaward) $15,000 (Year 2 Subaward) $2,175 (Year 2 Subaward) David Ellis, M.B.B.S. Catherine O’Connor, M.B.B.S., TREAT Asia Quality Assurance TREAT Asia Awards D.A. Ellis Pty, Ltd. F.A.Ch.S.H.M. Scheme Crofts Harbour, Australia Livingstone Road Sexual Health Treatment literacy project $1,500 (Year 1 Program Technical Centre Matthew G. Law, Ph.D. Pharozin Pheng Support Agreement) Marrickville, Australia National Centre in HIV Epidemiology Cambodian People Living with HIV/ $1,050 (Year 2 Program Technical $1,575 (Year 1 Subaward) and Clinical Research AIDS Network (CPN+) Support Agreement) $750 (Year 2 Subaward) University of New South Wales Phnom Penh, Cambodia Sydney, Australia $10,388 Robert Finlayson, M.B.B.S., Dip Ven David Orth, M.B.B.S., Dip Ven $161,468 Taylor Square Private Clinic Gladstone Road Medical Centre $119,623 (2006) Tenth Bangkok Symposium on HIV Darlinghurst, Australia Highgate Hill, Australia Medicine $450 (Year 1 Program Technical $6,525 (Year 1 Program Technical Prapahan Phanuphak, M.D., Ph.D. Support Agreement) Support Agreement) TREAT Asia Studies to Evaluate HIV Netherlands, Australia, Thailand $6,300 (Year 2 Program Technical $3,000 (Year 2 Program Technical Resistance Research Collaboration (HIV-NAT) Support Agreement) Support Agreement) Bangkok, Thailand Matthew G. Law, Ph.D. $20,000 Jennifer Hoy, M.B.B.S. Dr. Tim Read National Centre in HIV Epidemiology Victorian HIV Service, Infectious Melbourne Sexual Health Centre and Clinical Research Support for special analyses of epide- Diseases Department, Alfred Hospital Carlton, Australia University of New South Wales miological and clinical HIV research Melbourne, Australia $7,500 (Year 1 Subaward) Sydney, Australia Preeyaporn Srasuebkul, M.S. $7,500 (Year 2 Subaward) $6,300 (Year 2 Subaward) $165,530 University of New South Wales $156,297 (2006) Sydney, Australia Dr. Eva Jackson Norman Roth, M.B.B.S., F.A.Ch.S.H.M. $48,345 Blue Mountains Sexual Health and Prahran Market Clinic Pty., Ltd. Nagalingeswaran Kumarasamy, M.D., HIV Clinic South Yarra, Australia M.B.B.S., Ph.D. Katoomba, Australia $7,500 (Year 1 Subaward) YRG Centre for AIDS Research and Global Initiatives Awards $3,600 (Year 1 Subaward) $7,125 (Year 2 Subaward) Education, VHS $1,725 (Year 2 Subaward) Chennai, India Promotion of early CMV retinitis Darren Russell, Medicine $50,000 detection: A definitive teaching tool Mark Kelly, M.B.B.S. Cairns Sexual Health Service David Heiden, M.D.

The Prince Charles Hospital Cairns, Australia Sanjay Pujari, M.D. Pacific Vision Foundation Annual Report 2007 amfAR AIDS Medical Unit $5,925 (Year 1 Subaward) Institute of Infectious Diseases San Francisco, CA Brisbane, Australia $7,600 (Year 2 Subaward) Pune, India $8,200 21 $7,500 (Year 1 Subaward) $50,000 $7,500 (Year 2 Subaward) Dr. David Smith Emergency operating support Sexual Health and AIDS Services Adeeba Kamarulzaman, M.B.B.S., Felix Mwanza Dr. Anuja Kulatunga Lismore, Australia F.R.A.C.P. Treatment Advocacy and Literacy Northern Territory Dept of Health & $7,500 (Year 1 Subaward) University of Malaya Clinical Campaign Community Services, Sexual Health & $5,775 (Year 2 Subaward) Investigation Center Lusaka, Zambia

Blood Borne Virus Program, Clinic 34 Kuala Lumpur, Malaysia $2,000 Global Initiatives Darwin, Australia David Sowden, M.B.B.S. $50,000 $900 (Year 1 Subaward) Nambour General Hospital $975 (Year 2 Subaward) Nambour, Australia Christopher Lee, M.B.B.S., M.R.C.P. $7,500 (Year 1 Subaward) Sungai Buloh Hospital Mun Tong Liang, F.A.Ch.S.H.M. $7,500 (Year 2 Subaward) Sungai Buloh, Malaysia Nepean Sexual Health Clinic $50,000 Sydney, Australia Sharon Taylor, C.N.C. $1,875 (Year 1 Subaward) Hunter New England Health, Bligh Thira Sirisanthana, M.D. $1,350 (Year 2 Subaward) Street Clinic, Tamworth Sexual Health Chiang Mai University Service Chiang Mai, Thailand Simon Mallal, M.D. Tamworth, Australia $50,000 Royal Hospital/Department of $900 (Year 1 Subaward) Clinical Immunology and $675 (Year 2 Subaward) Somnuek Sungkanuparph, M.D. Immunogenetics Ramathibodi Hospital Perth, Australia Ian Woolley, M.B.B.S., F.R.A.C.P. Mahidol University $7,500 (Year 1 Subaward) Monash Medical Centre, Clayton Bangkok, Thailand $7,500 (Year 2 Subaward) Melbourne, Australia $50,000 $3,450 (Year 1 Subaward) Anne Mijch, M.B.B.S. $4125 (Year 2 Subaward) Praphan Phanuphak, M.D., Ph.D. Victorian HIV Service, Infectious Thai Red Cross Research Center Diseases Department, Alfred Hospital Bangkok, Thailand Melbourne, Australia $50,000 $7,500 (Year 1 Subaward) PUBLIC POLICY

arly on in the AIDS epidemic, amfAR established itself as both an effective proponent of comprehensive research, treatment, and prevention programs and a vigorous opponent of HIV-related stigma and discrimination.E Working with partners in the AIDS community and allies in Congress, the Foundation was instrumental in securing the passage of key legislation, including the Hope Act of 1988, the Ryan White CARE Act of 1990, and the Ameri- cans with Disabilities Act of 1990. To this day, that legislation forms the bedrock of the national response to HIV/AIDS. With more than 33 million people worldwide living with HIV/AIDS, including 1.2 million Americans, much work remains “At least a quarter to be done to shape domestic and international policies that of people in the U.S. adequately address HIV research, treatment, prevention, and the protection of the rights of people living with HIV/AIDS. living with HIV are quite Informed by thorough research and analysis, amfAR is a unaware of their infection. highly respected advocate of evidence-based and compassion- ate HIV/AIDS-related public policy. amfAR’s current advocacy And people who are PUBLIC POLICY priorities include: unaware of their infection • Securing necessary increases in funding for AIDS research, are likely to transmit prevention, treatment, and care; • Advancing a research and policy agenda that addresses the HIV to others.” social, structural, and economic factors that contribute to the HIV/AIDS epidemic; At the briefing, actress Gloria Reuben, who played an HIV- • Advocating appropriate federal funding for the U.S. positive physician assistant on the television drama E.R. and is government’s global HIV/AIDS programs; now an AIDS activist, called for increased awareness and dis- • Implementing an evidence-based, national HIV prevention cussion of HIV. “The thing that disturbs me most is to witness strategy; HIV become pandemic in the black community,” Reuben said. • Repealing the current ban on federal funding for syringe “AIDS is the number one killer of black women aged 25–34. amfAR Annual Report 2007 amfAR exchange programs; How could this be?” • Expanding access to treatment and care; and In February 2007, amfAR co-sponsored a conference in Los 23 • Safeguarding legal protections for people with HIV/AIDS. Angeles, It’s All About M.E.E. (Motivation, Education, Empowerment), which was organized by the Black AIDS Institute to address the HIV and Vulnerable Populations spread of HIV among African-American women. Public Policy Women make up nearly half of all HIV infections worldwide, according to the Joint United Nations Programme on HIV/AIDS Harm Reduction and Prevention (UNAIDS). In the U.S., the number of new infections among Numerous scientific studies—including many supported by women has increased steadily since the mid-1980s. Women amfAR—have shown conclusively that the distribution of of color have borne the brunt of this increase, with African- sterile syringes is effective in preventing the transmission of American women accounting for two-thirds of new AIDS HIV and other infections among injection drug users, without cases among women in 2005. Young women are increasingly increasing drug use. Despite the evidence, the U.S. persists vulnerable: by 2005, girls represented 43 percent of teenage in banning the use of federal funds for syringe exchange and infections. other harm reduction measures. To commemorate World AIDS Day on December 1, 2006, Although the federal ban remains firmly in place, advocates amfAR co-sponsored a congressional briefing titledHIV/AIDS in achieved a major victory in 2007 in Washington, D.C., where the U.S.: Focusing on the Needs of African-American Women. Panel- one in 20 residents is living with HIV. In 1998, the federal ists presented scientific and epidemiological updates and policy government banned the District of Columbia from using local recommendations, while testimonials from African-American taxpayer dollars to fund its own syringe exchange programs. women and young people illustrated the profound impact that Since the ban was imposed, amfAR has provided grants to HIV has on daily life for so many American families. The briefing support syringe exchange in Washington, D.C., and has been was co-sponsored by the Sexuality Information and Education vocal in its opposition to the ban. In 2007, both the House and Council of the United States (SIECUS) and AIDS Alliance for Senate finally removed the restrictive legislative language, an Children, Youth, and Families. advocacy triumph that was a decade in the making. In November 2006, amfAR sponsored the 6th Rethinking the Ground Rules for HIV Testing Annual Harm Reduction Coalition Conference, titled Drug User Health: The Politics and the Personal, t least a quarter of people in the U.S. living with in Oakland, California. In February 2007 and HIV are quite unaware of their infection,” said Dr. in collaboration with the Community HIV/AIDS “ Kenneth Mayer, an HIV specialist who serves on Mobilization Project (CHAMP), amfAR co-spon- amfAR’s program board. “And people unaware sored and participated in the planning of an HIV of their infection are likely to transmit HIV to prevention research advocacy workshop in Los others.” Angeles to educate community advocates about In the hope of getting more people to be the latest research and the need for improved tested for HIV and thereby reducing rates of transmission, in the fall of 2007 prevention strategies and technologies. AamfAR announced its support for making HIV testing a part of routine health- amfAR also organized a congressional brief- care. The move followed a shift by the Centers for Disease Control and Preven- ing in March 2007 to educate legislators and amfAR Annual Report 2007 tion, which abandoned previous guidelines that had called for HIV testing to be their staffs about the calamitous influence of in- performed only in tandem with counseling. jection drug use on the spread of HIV throughout Debates have surrounded HIV testing for many years, remembered Peter Asia and Eastern Europe. Entitled Drug Use Fueling Staley, an amfAR program board member. In the 1990s, “we were still living in a Epidemics in the East, the briefing featured a panel time of HIV exceptionalism,” he said. “HIV was not treated like other conditions of international experts who identified increased or other sexually transmitted infections because of the stigma involved and the injection drug use and a lack of harm reduction shock associated with getting a positive reading from an HIV test.” programs as drivers of the epidemic in those “But after the advent of highly active antiretroviral therapy, society came regions. Duong Truong Thuy of Vietnam, a a long way in its perception of HIV,” Staley explained. “One of the things that member of TREAT Asia’s Asian Community for 24 dawned on the medical establishment and activists was that HIV exceptionalism Public Policy AIDS Treatment and Advocacy (see page 19), in itself says stigma. Why shouldn’t this be like a hepatitis test, or cystic fibrosis? submitted a written statement to the brief- There aren’t all these restrictions on how to diagnose cystic fibrosis, nor should ing. Thuy, who was unable to attend in person there be for HIV.” because of U.S. policy restricting visas for people In his own practice, Dr. Mayer encountered the problems presented by with HIV, described his experiences as a former restrictions on HIV testing. “By creating a special system of having to get explicit injection drug user and the need for outreach and informed consent and having to mandate specific kinds of counseling and for drug users in Vietnam. “A lot of people think testing, impediments were being created ‘harm reduction’ sounds criminal,” he wrote. for healthcare workers,” he explained. “But isn’t it more criminal when you know how In recent years, concerns about patient to save people’s lives and you don’t do anything confidentiality have been assuaged by about it?” broad new federal laws. amfAR continues to support the only annual After a careful review of the evidence, national survey of syringe exchange programs in amfAR’s Public Policy committee and staff the U.S., which is published in the CDC’s reached a decision in early 2007. “We Morbidity and Mortality Weekly Report. And through felt that it would lead to broader testing a contract with the New York State Department to uncouple the medical process—the of Health’s AIDS Institute, the Foundation blood test—from the social process— administers the distribution of harm reduction counseling,” said Staley. “Ultimately that supplies to the state’s 17 authorized syringe would lead to saving more lives.” exchange programs. These programs, which also This amfAR-supported mobile unit in provide counseling, prevention education, and New York City provides HIV testing, medical and addiction treatment referrals, have syringe exchange, and other harm served more than 121,000 participants. reduction resources to those who most need them. amfAR co-sponsored a World AIDS Day congressional briefing examining HIV’s impact on black women and families. Panelists included (left to right) Candace Webb, Danielle Warren-Diaz, and actress Gloria Reuben.

Protecting Scientific Integrity Relief, which has brought treatment to millions in developing Annual Report 2007 amfAR amfAR’s Public Policy program is guided by the need to countries, has solid bipartisan support. amfAR will continue to espouse and enact AIDS policies that are firmly rooted in support these measures and other evidence-based policies that 25 scientific evidence rather than politics and ideology. The effectively address the treatment and prevention of HIV in the Foundation is a founding member of the Caucus for Evidence- U.S. and around the world.

Based Prevention, a group of more than 60 U.S.-based NGOs Public Poliicy and their international partners dedicated to the promotion of evidence-based policies for HIV prevention in the United States and internationally. amfAR is also a member of the Integrity of Science Working Group, which is spearheaded by the Union of Concerned Scientists and the Reproductive Health Technolo- 2007 PUBLIC POLICY GRANTS gies Project, and the Coalition to Protect Research, a group AND AWARDS of scientific, medical, and health organizations dedicated to All projects listed below were supported by amfAR promoting public health through research, including sexual during the period October 1, 2006, to September health research. 30, 2007.

National Black Women and Syringe Exchange in the US: A Shifting Landscape? HIV/AIDS Conference State of the Art and State of Phill Wilson Public Support There are encouraging signs that the political climate is shifting Black AIDS Institute Don Des Jarlais, Ph.D. in favor of more progressive HIV/AIDS policies. For the first Los Angeles, CA Beth Israel Medical Center $50,000 New York, New York time in a decade, Washington, D.C., will be able to use its own $75,000 funds to support syringe exchange and other harm reduction Research Advocacy for HIV Prevention: Skills & programs. Some members of Congress are also pressing for Challenges for Activists increases in biomedical research, as well as an end to travel Julie Davids Community HIV/AIDS restrictions that hinder the entry of HIV-positive foreigners into Mobilization Project the U.S. Additionally, the President’s Emergency Plan for AIDS (CHAMP) Providence, RI $3,000 EDUCATION AND INFORMATION

he dissemination of new knowledge gained from AIDS research is integral to all of amfAR’s programs. But keeping AIDS in the public consciousness and keeping healthcare professionals abreast of continuallyT evolving HIV treatment and care strategies requires an ongoing commitment to education and the distribution of information. Through its Education and Information program, amfAR provides updates on the latest research and treatment advances to physicians and other healthcare providers, and helps the public stay informed through the media, public awareness campaigns, the Internet, and a range of publications. Continuing Medical Education Each new development in HIV treatment alters the complex “It is important for us calculations that physicians must grapple with in their daily to remember that we’re decision making. amfAR is one of only a handful of nonprofit organizations accredited by the Accreditation Council for whole people, that Continuing Medical Education to provide HIV education credits we’re not just a virus.” to physicians. amfAR’s professional education courses benefit physicians, nurses, nurse practitioners, physician assistants, and others involved in caring for people with HIV. But the ultimate benefit resides in improved care for patients who must contend the power of exercise, of just trying to live your whole life as a with drug side effects, and lifelong monitoring and adherence whole human being.” to treatment. With drug use continuing to exacerbate HIV infection rates, One of the most serious challenges for longtime HIV amfAR co-sponsored the 2nd National Conference on Methamphet- patients is drug resistance. Over time, a patient’s virus will amine, HIV, and Hepatitis in Salt Lake City in February 2007. The inevitably mutate and evade the effects of one or more of meeting brought together public health officials, physicians, the drugs in a given regimen. However, new drug classes and advocates, researchers, and law enforcement personnel to find evolving treatment strategies offer hope for patients who have ways to diminish the influence of crystal meth use on HIV and exhausted other treatment options. From June to September hepatitis incidence. CME credits were provided to participating 2007, amfAR presented a series of educational programs for physicians. physician assistants and nurse practitioners entitled Improv- amfAR Annual Report 2007 amfAR ing HIV Treatment Outcomes and Care for the Treatment-Experienced Think Tanks and Symposia Patient. Attended by more than 550 participants and featuring The long-term success of HIV prevention and treatment is 27 case-based interactive presentations integrated with study inextricably linked with educational programs that meet data, the CME series was held in Raleigh-Durham, North current and future needs. To identify and plug education gaps, Carolina; Albany, New York; San Diego; Los Angeles; Denver; amfAR organized a series of eight think tanks in 2007 that Atlanta; Indianapolis; Portland, Oregon; Kansas City, Missouri; brought together health experts, community members, and care and Boston. providers from around the country to share best practices and amfAR also conducted community forums on drug resis- develop strategies and goals. Separate sessions for clinicians Education and Information tance in 2007—one in Seattle in January and a second in Las and community members were held in San Francisco, New York, Vegas in May—titled Understanding Antiretroviral Therapy: Lessons Chicago, and Miami. for the Treatment-Experienced Patient. Each forum was attended by In commemoration of World AIDS Day 2006, amfAR nearly 100 participants, including treatment-experienced partnered with Columbia University’s Mailman School of Public individuals, caregivers, social workers, educators, nurses, and Health to organize a symposium entitled HIV Prevention Among other healthcare providers. Support for the meetings was Men Who Have Sex with Men. The symposium, which took place in provided by Boehringer Ingelheim and Gilead Sciences. late November, featured an international panel of experts who At the Seattle community forum, panelists discussed new discussed the epidemiology of HIV among men who have sex treatment strategies, recently approved drugs, and the with men (MSM), as well as prevention methods, prevention importance and difficulties of adherence—but they also challenges among African-American MSM, and healthcare for emphasized that treatment is only one aspect of living with HIV. MSM in the developing world. “It is important for us to remember that we’re whole people, that we’re not just a virus,” said patient advocate Pat Migliore. Spreading Knowledge, Raising Awareness “We have to be really responsible as patients to make sure that In recent years, efforts to institute abstinence-only sex educa- we round out the rest of our lives. I’ve heard it again and again tion in schools across the U.S. have led to a dangerous lack of in here tonight—the power of prayer, the power of spirituality, knowledge among many young people about HIV transmission Sharing Expertise on Treatment-Experienced Patients and prevention. In addition, recent advances in HIV treatment, which have helped to extend the lives eattle internist Dr. Peter Shalit sees hundreds of patients in his of people with the virus, have fueled a widening medical practice, about half of them living with HIV. Over the belief that HIV/AIDS is no longer a serious illness. course of his career as an HIV specialist, Dr. Shalit has worked These developments highlight the ongoing need to keep his patients healthy, but his choices get much more for accurate, science-based public information on complicated when they develop resistance to one or more of HIV/AIDS. their drugs. amfAR’s print and electronic publications, “It used to be until a couple of years ago that we couldn’t which are distributed in the U.S. and around the really do anything for people [with drug resistance] except to world, help to fill this information gap by providing Ssay, ‘stay on what you’re on or we’ll give you a cocktail that doesn’t make you sick, up-to-date news on research developments, HIV/ and hopefully things will kind of stay stable for a while’,” Dr. Shalit said. AIDS policy, the social and economic impact of

amfAR Annual Report 2007 Today, more than 20 anti-HIV drugs are available, but Dr. Shalit and others who the epidemic, and HIV prevention. amfAR News is care for treatment-experienced patients still confront a daunting challenge. “The published twice a year and distributed to 70,000 folks who have resistant viruses are not a majority,” he explained, “but treatment people. A monthly email newsletter reaches more for them is more sophisticated.” than 40,000. The TREAT Asia Report, which includes Along with a small group of HIV experts, Dr. Shalit (son of film critic Gene Shalit) news on the Asian epidemic and updates on served on amfAR’s planning committee for the Continuing Medical Education amfAR’s TREAT Asia program, is a quarterly (CME) series entitled Improving HIV Treatment Outcomes and Care for the Treatment- newsletter that reaches an international audience Experienced Patient (see page 27), and took a leadership role in creating the commu- of 15,000. nity education portion of the program. He also assisted with content development The Foundation’s website, www..org, 28 and spoke at the physician and community forums that addressed the topic. “This receives an average of 55,000 visitors each month. Education and Information is an issue a lot of providers are unaware of,” he said. “I try to educate them. It is Updated daily, the site explains AIDS research and easy to harm someone by giving them a new regimen and having it fail. policy developments, and disseminates a wealth of “This virus is very crafty. It takes advantage of any little opening that a person information on HIV prevention, testing, epidemiol- will give it,” Dr. Shalit said. “But my personal feeling is that with proper treatment, ogy, and amfAR’s programs and activities. amfAR someone with HIV should have the same life expectancy as someone without HIV.” also develops and distributes reports, fact sheets, and issue briefs on a wide range of HIV/AIDS research and policy issues.

“With proper In addition to treating hundreds treatment, someone of HIV-positive men in his Seattle practice, Dr. Peter Shalit educates with HIV should healthcare professionals on the latest strategies for treatment-experienced have the same life patients through amfAR’s Continuing expectancy as Medical Education programs. someone without HIV.”

amfAR Chairman Kenneth Cole and New York City Health Commissioner Dr. Thomas R. Frieden help launch the NYC Condoms program. amfAR Annual Report 2007 amfAR

In spring 2007, amfAR sponsored a national survey to Post, the International Herald Tribune, the San Francisco Chronicle, 29 assess public perceptions of women living with HIV/AIDS. The New Yorker, The Advocate, Reuters, the Associated Press, The results showed pervasive negative views of HIV-positive CNN.com, LATimes.com and Forbes.com. women and a high level of discomfort in interacting with On World AIDS Day 2006, amfAR chairman Kenneth Cole them. Many of the responses displayed a lack of knowledge appeared on the Discovery Health television network in public of how HIV is transmitted and misplaced fear of contracting service announcements about HIV/AIDS. He also participated the virus that indicate a pressing need to scale up prevention in exclusive video and audio interviews on the network’s web- education efforts. Conducted by Harris Interactive for amfAR, site and in an iTunes podcast. Also for World AIDS Day, amfAR Education and Information the survey questioned nearly 5,000 respondents aged 18–44 CEO Kevin Robert Frost appeared on New York’s WCBS TV and covered HIV risk and responsibility, the impact of gender- news to speak about the urgency of addressing the epidemic. based violence, and women’s access to healthcare and health amfAR’s ability to make its voice heard internationally is information, as well as attitudes towards HIV-positive women. considerably enhanced by the active participation of public The survey was made possible by grants from Broadway Cares/ figures. Celebrities from the fields of music, film, fashion, and Equity Fights AIDS and the M•A•C AIDS Fund. fine arts generously donate their time, talents, and resources to advance amfAR’s mission and raise funds in support of Beating the Drum it. amfAR is especially indebted to Dame Elizabeth Taylor In an era of short attention spans and furious competition for and Sharon Stone for their innumerable contributions to the the media spotlight, keeping AIDS on the public radar screen Foundation and the cause of AIDS research. Others who gen- requires continual outreach to the media. As a prominent voice erously lent their voices and support in 2007 include Woody on HIV/AIDS for more than 20 years, amfAR is sought after by Allen and Soon-Yi Previn, Tracy Chapman, Richard Gere, Paris the media for expert commentary on AIDS research and policy Hilton, Cheyenne Jackson, Eve Jeffers, Milla Jovovich, Beyoncé issues. In 2007, amfAR was repeatedly called on to provide Knowles, Liza Minnelli, Kylie Minogue, Natasha Richardson, expert commentary on the latest research findings. Outlets that Julian Schnabel, Liz Smith, Stanley Tucci, Dita Von Teese, featured amfAR and its researchers included The Washington Harvey Weinstein, and Michelle Yeoh. GIVING

amfAR’s accomplishments in the fight against AIDS would not be possible without generous support from individual and institutional amfAR Annual Report 2007 donors. There are many ways you can join us in our efforts to end the global AIDS epidemic.

Donate online at www.amfar.org 30 Write a personal check. Giving Make a gift in honor or memory of a loved one. Include amfAR in your will or other estate plans. Join the “Friends of amfAR” monthly giving program. Ask your employer to match your gift. Designate amfAR in your workplace giving program. Give a “Partners for the Cure” gift of $1,000 or more. Consider a gift of stock or other assets. Attend or sponsor an amfAR benefit event. Donate goods or services.

For more information, call us at (212) 806-1600 or e-mail [email protected] Individual Giving

Generous support from individual donors forms the backbone of amfAR’s efforts to control and eradicate HIV/AIDS. The following individuals and families contributed or raised $1,000 or more between October 1, 2006, and September 30, 2007. amfAR acknowledges with gratitude the thousands of other donors whose generous contributions, tribute gifts, and benefit event ticket purchases have helped bring us closer to our goal of a world without AIDS.

John and Lisa Runyon Hanym Ben-Halim $25,000+ Mohammed Y. El-Khereiji Geoffrey Raynor Carole Bayer Sager and Jean K. Benjamin Lee and Penny Anderson Jeff and Regen Fearon Corrado Riccio Robert Daly Anthony Bergamo, Esq. Gabriel and Ann Barbier- Glenn R. Fuhrman Bruce and Avis Richards Mark Sandelson Cary D. Berman and Mueller Gladwin Gill, M.D. Vincent A. Roberti Steven R. Shareshian Roy B. Hamm Angela Barrett Kenneth Goss and George Edward Rose, III and Samuel and Hannah Shipley Jerome J. Berner Yannis Bilquez Michael Evelyn P. Rose Jim and Jan Showers Anthony M. Berson, M.D. Jaka Bizilj Timothy G. Hanlon Rusty and Deedie Rose Victoria Silvstedt Gerard A. Bertolino David C. Bohnett and Tom Michael Hirtenstein David G. Rosenberg Barry C. Skovgaard and Priscilla Beshears Gregory Marguerite S. Hoffman Nathaniel Rothschild Marc O. Wolinsky Lucy and Henry Billingsley Jean R. Boulle James C. Hormel Daniel and Elizabeth Sharon Stone Allen D. Black and Randy Hermann Bühlbecker Anita M. Jaffe Routman Harold Stream Apgar Tim Byrne Bob and Susan Kaminski Phillip H. Rubin and Allen L. Blaich Luigi Caiola and Sean Maurice Kanbar Lily Safra Stephanie Rutherford Daniel L. Blakemore McGill Donna Karan Cynthia Sarkis Perros Roderick B. Thomson Kurt and Margot Bloch Donald A. Capoccia George and Karen Kollitides Alan D. Schwartz Ralph M. Vicinanza Daniel and Laura Boeckman Roberto Cavalli Mathilde Krim, Ph.D. Natalia Selivanova Patrick Wade Joseph Boerjes Fabrizio Cerina John and Carol Levy Gary A. Tigges, M.D. Anonymous (4) William and Clare Bohnett R. Martin Chavez, Ph.D. Michel Litvak Donald J. Toumey and Brian R. Bolke amfAR Annual Report 2007 amfAR Robert and Suzanne Chute Sheila W. McAdams Paul Chen $1,000–9,999 George and Eleanor Bollag Giuseppe Cipriani Patrick and Suzanne McGee Edward Walson Armand Abhari Paul and Maxine Bradley Kenneth and Maria Cole Michele V. McNeill, Pharm.D. Kevin Wendle Celiena Adcock Peter Bradley and David R. 31 Ugo Colombo Alexandra Melnichenko Derek and Christen Wilson Warren and Jan Adelson Krimm Kenneth and Patricia Crews Jerome and Ann Moss Steven Witkoff Gil and Jeannette Adler Scott Brady Rex Cumming David J. and Nancy Nasher Jonas and Nicole Woods Jay L. Althouse and Sally K. Brent Brake Giving Sindika Dokolo Aviv Nevo Steve Wozencraft Albrecht Philip D. Brandt Vladislav Doronin Ronald Perelman Michael and Sharon Young H. John Amiri and Janet Stephen Brauer Umar Dzhabrailov John and Amy Phelan William and Deborah Zabel Amiri Zev and Mayling Braun John and Jennifer Eagle Howard and Cindy Luigi Zunino Arlen and Michele Andelson Arthur L. Brown Amir and Maria Ecker Rachofsky Anonymous Kurt Anderson Brent Brown Walter and Laura Elcock Michael Rawlings Joseph L. Arena Constance A. Brown Elizabeth K. Armstrong David S. Brown $10,000–24,999 Davidson Mary Ann and Allen Lassiter Ralph Arnold, III and John Gavin Brown Frank Aldridge, III and Bob Dedman, Jr. and Laurence H. Lebowitz and Hannan Lloyd R. Brown Brooke Aldridge Rachael Dedman Naomi Aberly William G. Atmore, M.D. Robert Bryan and Julie A. Omar Amanat Lord and Lady Luis del John and Eleanor Lemak Raul Avila Jensen Louis Andy Campo Bacardi Bruce Lipnick Alex Badia Todd Buchanan Paul Arata and Scott Foster Stuart M. Elsberg Michael K. Longacre Richard K. Baird, Jr. Laurie Burns Nicholas Augustinos and Bess and Ted Enloe Bill and Suzanne Marcus Ken and Ginger Baldwin James and Debbie Burrows Curt Kirschner Katherine Flanagan Richard L. Martin Ray A. Balestri Judd Burstein Steven and Carrie Becker Judy E. Francis Zankel Richard H. Metzner and Merrill Barlow, IV Barbara F. Buzzell Christian J. Beherman Jack P. Freinhar, M.D. Mark Sapitsky David Barnett Molly Byrne Jeff Berg Robert and Ann Fromer Rodney Miller Daniel Barney Renee Cafiero Christina Bloom Gordon and Ann Getty Hon. and Mrs. Michael David Barr and Sam Avrett Walter M. Cain Carla Bruni Eliot Glazer Misick Dan Bartley Karen Campbell Vincent Calcagno Thomas and Deborah Green Nancy and Clay Mulford Ben Barzune Jonathan S. Canno David M. Carrillo and Lisa Jon Halpern Daniel P. Padnos and Scott Bass and Dominic F. Sherman R. Card Sardegna Daniella Helayel Dexter M. Phillip Chiarello Stephen P. Carlino and Tracy Chapman Richard and Sally Henriques Lucilo A. Pena Bruce W. Bastian Dennis R. Fee Vikram Chatwal and Priya Sally Horchow H. Ross and Sarah Perot Alvin H. Baum, Jr. Frank Carucci Sachdev Howard Katz Carol A. Prugh Leo and Naomi Beck Robert and Dolores Steven and Alexandra Alfiya Kuanysheva Nicolas Rachline George W. Beddingfield Cathcart Cohen Harry Kubetz and Gary William and Catherine Rose Lois Beishir Tracy B. Cather Dennis and Janette Burton Robert Rosen Pamela and Al Bendich Satjiv S. Chahil Matthew Chang Sheryl A. Dreyer Tom Freudenheim Steven and Nicole Harf Daniel J. Keyer Martin Samuel Checov Michael and Bobbie Ruthellen Fried, M.D. Irwin and Carolyn Harris Richard M. Kielar and Cameron A. Clarke Drukman Stephen Friedman Annelise Harstick Christian Zimmerman Robert W. Clausen, M.D. Ferrell D. Drum Ronald and Carol Friedsam Margaret S. Havens Bruce C. Kleiman Michael P. Clifford and Jeff Dulock Robert W. Frierson Michael H. Hayes David Kleinberg Robert Levy Jay P. Duncanson Cynthia E. Frost Brook Hazleton Michael and Kathleen Anthony and Catherine Scott H. Dunham and Charlotte Frye Dana A. Hearn Klestoff Clifton Barbara Eliades James W. Gallagher Troy P. Heiden Michael and Ruth Stewart and Kimberley E. Thomas M. Dunning Jonathan Gans and Abigail Martin C. Hemsworth Klingensmith Cohen Norman A. Dupont Turin Mark E. Henderson and Bryan W. Knicely Kim Colby Charlotte S. Dutka Melanie J. Garner and Bruce Wolfe Alex J. Kochnuk Eric Coleman Stefan and Wendy John F. Sienkiewicz Barry and Lana Hendler William G. Kocol Scott Coleman Dyckerhoff Stanlee Gatti Brett Henne Kenneth F. Koen Michael and Linda Connelly Marjorie L. Dyer Earl C. Gauger John W. Hering David A. Kourlas Patrick and Ginger Connolly James Z. Eakes David A. Gentry Michael Herning Ronya and George Albert B. Connor Olga Echevarria and Kevin D. Gertgen John B. Hickey Kozmetsky Alfred and Alvina Contarino James C. Hudton-Wiley William and Vanessa Getty Al Hill, III and Elin Hill Michael and Shelley Krall Frank P. Conway Dory Eckstein Gary L. Gibson Ritchie Q. Ho Ella Krasner

amfAR Annual Report 2007 Joseph H. Cook Israel and Edith Edelstein Raymond and Johnnie Lee and Ann Hobson Peter and Lisa Kraus Andrew and Wendy Cookler Jamshid and Mahshid Gillespie Mary J. Holland Robert W. Krause, M.D. Nancy and Bruce Cooper Ehsani Gregory W. Gingery Thomas C. Holland Daniele Kucera and Richard and Fara Copell Richard and Betsy Eiseman Harold H. Ginsburg Todd Holland and Jeffrey M. Khaner Michael Corman Leslie El Effendi William A. Glasgow Scotch Ellis Loring Mark J. Kulkis George B. Cotkin John M. Ellenwood Lewis N. Glassman Chris and Holly Hollenbeck Frances E. Kumashiro Tom Crane and Richard Robert J. Elsen Richard and Carolyn Douglas A. Holtquist Jeff and Terry Kurz Louie Thomas and Filomena Glickstein Paul and Nadine Hooker William Kwan Christopher Crowley Emanuel Ray H. Goetz Tony and Kim Horton Chal and Chuok Kwon William L. Cruise Dwight and Claire Kay E. Goldberg, Ph.D., Willem Houwink Brian and Rachel Ladin Graham and Kimberly Culp Emanuelson L.Ac. Jack Z. Hruska Jonathan Lamensdorf Mimi F. Cummings Norman and Susan Ember Whoopi Goldberg David L. Hughes William and Mary Lamont J. Patrick Curry Gregg L. Engles John and Marcia Goldman Robert G. Hulteng Maree B. Larson 32 Timothy and Denise Curry Richard and Tucker Richard N. Goldman Arthur F. Humphrey, III Mark H. Laughlin Michelle Curtis Enthoven Andrew D. Goodman and Raye Hurwitz, M.D. Frank and Kathleen Giving Allen and Mason Custard David W. Entsminger Myra Rubin Najah Hussain Al Muntafiq Lauinger Steven Czekala, D.D.S. Lucille Z. Epstein James P. Goodman Julian Iragorri Jeff Leatham Don and Barbara Daseke Jeff and Shannon Estes Bryan E. Gordon Joel Isaacs Sonia Lee and Alan M. Joan C. Davidow Richard A. Eustice and Harold C. Gordon Mark A. Itkin Grumet Sean Davis Donric A. Hall Joyce Goss Gavin and Martha Ivester Lois A. Lenahan Lori and Richard Day Kenneth J. Evanoski Randall G. Goss Grace Izmirian Edward C. Lenhart Juliet de Baubigny Caroline L. Everts Judson and Rosalind Gostin Alyson Jackson Carl Levine Michael and Deborah Dean William L. Exeter Milton and Barbara Gottlieb Cheyenne Jackson Dominique Levy Glynn and Sonia Decoteau John and Susan Fabian Eliot P. Graham and Steven N. Jacobson Jay and Sharon Levy Alan S. Dejarnette Gary T. Farrar John M. Celowanchik Henry G. Jarecki Scott and Allison Levy Salvatore Delorenzo James K. Farrell Anthony and Linda Grant Suzanne Jed F. Bruce and Diana Lewis David and Sylvia Dennison Vernon E. Faulconer Leslie and Joel Greenberg Mrs. Lyndon B. Johnson Erica Lieberman Craig Deodede Jim Fechtenbaum Brad Greenspan Luci B. Johnson Richard Linebaugh Victoria A. Derdivanis Elisha Feder Gregory W. Griffith Gregory Jones John S. Lipsey and Traci Des Jardins Dean R. Feldman Thomas J. Gross Dorothy C. Joseph John E. Alexander John Desmarteau, M.D. and Duane Fernandez, Jr. Seth Grosshandler and Shaji Joseph Steven Lisker Alvin E. Thompson Mark Fichandler and Paul Kim Wainwright Jeffrey Judd and Colleen Michael P. Liskowycz Henry Detering Travis Michael A. Gulish Prince Jeff Little William and Heidi Dillon Joseph S. Fichera Dolph Haas Mark A. Kadzielski William E. Little, Jr. and Michael J. Dion Eric K. Fischl John and Chara Haas Vinod Kalathiveetil Helen Little Salvatore E. Dirschberger Rebecca and F. Barron Alexis B. Hafken Al Kamhi Ming S. Liu D. Kevin and Lisa Dolan Fletcher Robert S. Hagge, Jr. Christopher Kamradt and William and Michelle Paul and Winifred Dooley Miriam Fond Ricardo Halac Janus Valbak Lockhart Simon D. Doonan Curtis Forsythe Jeremy and Nancy Halbreich Donna Kaplan Arthur L. Loeb Jason Dorn William L. Fortune, Jr. and Kenneth Hale Joan E. Karan John Lomibao Pierre J. Dosogne Joseph D. Blakley Howard Hallam Mary A. Kautz George M. Lorenzo Donald G. Dotzauer George Foukas, M.D. Richard V. Hamilton Christopher G. Kelly, Jr. and Joseph and Susan Losak Angelique Dove Hatch Kevin C. Fox Tim and Nancy Hanley Etta Lamberti-Kelly Jesse and Patricia Lovejoy Judith A. Dove David Frankel Fredric Hanson Charles T. Kennedy Mr. and Mrs. Lawrence Joe Dowling and Siobhan Bill Freeman Kevin L. Harder J. Christopher Kennedy Ludgus Cleary David Fremont-Smith Holly A. Hardman Kyle F. Kerr Francis A. Luttmer Randall G. Drain Phillip French Ruth and Rolf Harf Bernard Kester Ruth Luttmer Trek amfAR Morton Milder Howard J. Miller Fred and Susan Miller amfAR staged its third physical challenge fund-raising event, Trek amfAR in Africa, in May William and Patrica Miller 2007. More than 20 amfAR supporters took a ten-day trek through the Namib Desert of Judith R. Minor Ronald P. Minutella Namibia and learned firsthand about the AIDS crisis in sub-Saharan Africa. Trekkers raised Presley Mock, M.D. and $251,000 for amfAR’s programs, led by Peter McManus of Los Angeles who generated Lynn Mock Ronald and Kerry Moelis $40,000. Warren Moen Cynthia Molstad Elena J. Mondini Helena Buzzeo Rowena Johnston Ramneek Rikhy Robert Montagnese Sushama Cisson Natalie Kates Sandra Roy Susan B. Montgomery Derek Cordier Harry Kubetz Danielle Schofs Alona Moore Rainer Facklam Maura Lee John Tarro David E. Morales, M.D. Julie Gilhart Peter McManus Albert Vaccari Michael D. Morgan Patti Gomes Brandon Palacio Michael Walsh Bruce and Donna Morse Glenn Isaacson Dexter Phillip Jenny S. Morton and Mike Wilson John Motondo Jenny Mullen Don Mullins John and Marilyn Murbach Jerry Nahay Edward Tyler Nahem Marty Nealon and Richard Aellen Robert O. Newbury

Mark E. Newell and Annual Report 2007 amfAR Jo Ann L. Newell Adina M. Newman 33 Paul Newman and Joanne Woodward David and Antigoni Newton Connie Ngai Giving Mark Niquist

Paula A. North amfAR Donors Rosie O’Donnell David J. Olesker Joe Olivo and Jeff Wiggins Jay W. Oppenheimer Tom Osborne Mary A. Ostrom M. Chris Overby, M.D. Trekkers rest at an abandoned farmstead. David T. Owsley Robert K. Ozanne Jay and Ruthie Pack Susan L. Page Sonia G. Palacio Bobby B. Lyle Bruce and Gloria Mark N. McConnaughay Victoria L. Meakin Maxwell G. Paley and Frank and Joan Macero Martindale William and Patty Kathryn D. Meister Gregory J. Corrales Thomas S. Magaraci Patricia J. Matson McCormack Bill Melamed, Jr. Daniel and Amy Palladino Todd J. Maldonado William M. Matthes Andrew McFadden Jeffrey D. Meleski Alvin L. Park Irving and Harriet Malitson Christine Mattsson McHale Cappy and Janie McGarr Ron and Wendy Meltsner John and Diana Park Eric C. Malley and John McHale James J. McInerney and Alvaro R. Menendez Joan Parker Carey C. Maloney and David J. Maue and Dave Gary R. Fafard Richard and Ronay Gary and Pamela Patsley Hermes Mallea Gaudette Gordon N. McLeod and Menschel C. Sprague Paynter Michael D. Manshel T. Kirk May, Jr. Melanie Grisanti Manuel R. Merjil Nivia Pedroza Claire P. Mansur and Douglas G. Mayberry Casey and Megan Julie Mesa Thomas E. Pedulla John P. Ryan Kenneth H. Mayer, M.D. McManemin Frank L. Miceli David N. Pennington Steven Mao Mario and Luciana Mazzola Jay McNamara Janet G. Michaels Roberta Perez Robert Marc Alexander McAfee Suzanne R. McPhee Neli P. Mihalkova Christopher A. Perrault Norman Marks Thomas McArdle Rochelle McReynolds Frank and Maryann Robert Perri and John J. Timothy F. McCabe David R. McShane Mihalopoulos Mini Jack M. Perry, Esq. Gregory and Lysa Rohan Jesse B. Shelmire, IV and Greg M. Swalwell Neal Ward Richard and Lisa Perry George Rosenfield and Michelle Shelmire Richard F. Swenson Robert L. Warner, M.D. and Marjorie L. Pflaum Christopher Hoover Rodney Sher and Mary Dale and Denice Swift Larry Bobel Kevin P. Philbin Brian Roth Tobin Lucille Swindoll Marshall Watson and Paul Eric A. Pike Naomi Rothschild William F. Sheridan Carol Tacker S. Sparks David N. Pincus Sandra A. Roy Allan P. Sherman Robert F. Tannenhauser Steven G. Wedge Alden Pinnell Iris R. Rubinfield Timothy and Beth Shields Pamela Tarro Edward and Betty Michael C. Pinson Frances E. Ruddell James Shimizu Jason and Leigh Taylor Weisberger James C. Pirius Peter and Sally Rudoy James C. Shingle Jim Taylor and Anthony Don Weiss Barry and Penny Platnick Lawrence Ruff Gresham Jay Shinn, Jr. and Luongo Marco and Joan Weiss Gloria Polastri James Saakvitne and Tim Hurst Julie Taymor Warren Weitman, Jr. Richard and Karen Pollock Chi Yuen Chow Tina Shone Rick and Sandy Thomas Doris K. Wells Daniel J. Ponder Mitchell Salaway Stephen and Wendy Siegel Paul Thompson John Wendell Patricia Pope Steven S. Saleh Douglas Sills and Todd Shirley Thompson Mona L. Westhaver Adrianna M. Pope Sullivan Dorian P. Sarris Murray Regine Thorre Gary and Nina Wexler Fern Portnoy Mitchell and Bonnie Cameron Silver Andrew P. Tobias Francis W. White Kevin M. Poulos Sassower Albert and Kimberly Silvera Gregory A. Tosko Hall F. Willkie and Thomas Joe Powell Tony M. Scelza Mervyn and Deborah Christopher D. Tower Craveiro amfAR Annual Report 2007 Nani B. Powers Robert Schaffer Silverman John Traina Richard A. Wilpon Randy M. Presuhn and Dennis J. Schank Lee Simerman, M.D. Garry Trudeau and Diane B. Wilsey Timothy Nguyen Leonard J. Schaustal, Jr. Robert G. Simon and Gilles Jane Pauley Aubin E. Wilson Aleksey Pryadko Roger E. Schechter and DeVoe Ivana Trump Brian Wilson Jach Pursel Craig P. Ziskin John and Betsy Simons Brian C. Trust Susan A. Winchell, M.D. Kelli and Allen Questrom Steven V. Schmitz Patricia J. S. Simpson Stanley Tucci John and Barbara Robin O. Quivers Ronald I. Schnur Rosalyn Sinoway Douglas H. Tucker Winkelman Seth D. Radwell Harry Schoening Catherine H. Skove Richard and Adrienne Tufeld William T. Winters, Jr. and Jerome and Karen Radwin Danielle Schofs Eric and Susan Smidt Matthew D. Tumminello Adriana Winters William and Marcia Rafkin Katie Schwab Frank C. Smith Sheldon G. Turley, Jr. Andrew Wise John A. Ramelli, III Armond and Cynthia Mark D. Smith and John Alexander J. Turner C.R. Wishner Jeanne G. Rand Schwartz O’Keefe Heather L. Turner Jack and Lynda Withiam, Jr. Allison Rao Carol S. Schwartz Joseph Sokolosky Richard F. Turner Myron Wojtowycz, M.D. 34 Karl and Carolyn Rathjen Daniel and Barbara Nira Soomekh Robert L. Turner Derik Woods Giving Jordan H. Rednor Schwartz Murat H. Sor, M.D. Kathleen E. Tyrrell Sum Wu Peter S. Reichertz John Schwartz James E. Southworth Robert D. Uher Timothy Wu Brian Reid and Brett Sherwood and Mildred Stan Sroka Kenneth W. Usher Rick Wulff Brenner Schwartz Christina and Sean St. Clair Mandana Vahabzadeh Gordon Youngman Jose R. Reyes Steven T. Schwarz and Miles Peter Staley and Gary James Vergara Ryan Zanin Anthony J. Richardson Kahler Schwartz Dale E. Verlinger Larry Zerner and Temple S. Richardson Gerald J. Seibel Kathryn and Timothy Tom Vinci Graciela Renee Edberg Walter Rieman in Memory James R. Seitz, Jr. Statton David and Karen Wacker David Zippel and Mike of Tom Stoddard Neil L. Selinger and Sue E. Stedman Gerald and Ellen Wacker Johnson Leonard and Peggy Riggs Rima Grad Alan and Cathy Steel Thomas M. Wade Anonymous (13) Timothy A. Robert Kristen Sellgren and David Tom and Blake Stephenson Stephen Wagner and Bonnie G. Robins J. Ennis Andrew T. Stewart Simon Beachley James E. Rocco Dennis Senovich Kristin K. Stitz and J. Scott Barry C. Waldorf David Rockefeller Leslie Serchuck, M.D. Coleman Darren Walker Howard Roffman and David M. Serna Paul and Gayle Stoffel L. Joseph and Karen Walker Duane Waters Adam Shankman Stephen Straty Richard and Jennifer Walsh Leila A. Rogalsky Lionel Shaw Steve and Emily Summers William E. Walsh, Jr., M.D.

If you or your organization has been inadvertently omitted from these lists or listed incorrectly, please accept our apologies and contact amfAR at (212) 806-1732 so that we can adjust our records accordingly. Institutional Giving amfAR is grateful to the many institutions large and small that support the fight against AIDS through grants, event sponsorship, cause-related marketing activities, and in-kind contributions. Major corporate support comes from business sectors ranging from film, fashion, and fine arts to financial services and pharmaceuticals. Additional generous support is provided by corporate and family foundations and by a wide range of civic associations, social clubs, cooperatives, schools, and churches.

$1,000–9,999 Craig Nealy Architects LLP $25,000+ Fashion Accessories Benefit Plaza Motors of Brooklyn 2c design Crawford Communications, Alberta Ferretti SpA Ball Ltd. Abbey Properties, LLC Inc. Avanti Federated Department Quintessentially The Active Network CRR Ventures, LLC Stores Foundation Red Pillar Realty LLC Adelson Family Foundation David Kleinberg Design David Bohnett Foundation Bill & Melinda Gates Red Ribbon Foundation The AEG Family Foundation Associates Bold Films, Inc. Foundation May Ellen & Gerald Ritter American Express The Irene Diamond Fund Broadway Cares/Equity GlaxoSmithKline Foundation Foundation Diesel U.S.A., Inc. Fights AIDS, Inc. Richard and Rhoda Roberto Cavalli SpA Fred & Catalina Aranas Discovery Communications Cartier, Inc. Goldman Fund Rock & Republic Family Foundation Douglas Foundation Chi Eta Phi Sorority, Inc. The Halcyon Company Sergio Rossi Astec Power Duro Dyne National , Inc. Harry Winston, Inc. Skyy Spirits, LLC AT&T California Corporation Chopard Hewlett-Packard Company Sotheby’s Avrum Katz Foundation Edgell Communications, Inc. Christian Couture JG Events Swarovski America Ltd. Azzaro Edward Sulzberger Chubb Elton John AIDS Foundation The Elizabeth Taylor AIDS Bay Area Physicians for Foundation, Inc. Concerned Parents for AIDS Kenneth Cole Productions Foundation Human Rights Thomas and Jeanne Elmezzi Research Krehbiel Family Foundation Tibotec Therapeutics BCM USA, LLC Foundation The Copley Press, Inc. M•A•C AIDS Fund Time Inc. Bennack-Polan Foundation Elmwood Country Club Annual Report 2007 amfAR de Grisogono USA, Inc. Merck & Co., Inc. Trade Associates Group Ltd. Bergman, Walls & Nora Ephron and Nicholas Denise Rich Music, LLC Moët Hennessy Verein AIDS Life Associates, Ltd. Pileggi Foundation 35 Diamond Information The Ambrose Monell Warner Home Video, Inc. Bernhardt Showroom Equinox Foundation, Inc. Center Foundation Wasserman Foundation BJ’s Home Accents, Inc. Estilo, Inc.

Diesel, SpA MTV Networks The Weinstein Company BlackRock Financial Extraordinary Investors, Ltd. Giving Dubai International Film Mymetics Corporation Wells Fargo Management, Inc. Feldman Family 1995 Festival Namakwa Diamonds Yves Saint Laurent Blue Mountain Arts Charitable Lead Trust Dutch Ministry of Foreign Limited The Ruth/Allen Ziegler Boehringer Ingelheim Fine Lines Co. Affairs Nassiri Music Foundation Pharmaceuticals FJC The Eisner Foundation Omega Diamonds Anonymous (4) Brian E. Boyle Charitable Flamm Family Foundation Estee Lauder, Inc. Parfums Christian Dior Foundation Flaxman Family Charitable Family Health International The Picower Foundation Bridges/Larson Foundation Trust Bulgari UK Fragments Collection, Inc. $10,000–24,999 Initial Entertainment Group Walter H. & Phyllis J. Bungalow, LLC Fred B. Bearden, III & The Aliquot Foundation The Karma Foundation Shorenstein Foundation Cable Positive, Inc. Associates, Inc. AMC, Inc. Laurie Kayden Foundation Star Entertainment Carbon de Luxe Freeman Decorating Bloomberg John & Maria Laffin Trust Stephen Friedman Fine Art Cars4Charities Company Cousins Brett Leibowitz and Greenway StepUp Commerce, Inc. Charity Folks The Abraham Fuchsberg D & DF Foundation Family Charitable Talcott Communications Chelsea Eye Associates Family Foundation, Inc. DaimlerChrysler Foundation Corporation CHIS, Inc. The Leo & Eva Gans Corporation Fund Carol Anne Levy Foundation The Tides Foundation Christian Dior Foundation, Inc. Dallas Market Center Liz Claiborne, Inc. Title Associates Chubb & Son, Inc. Ganz Inc. Disney Worldwide Services, Louis Vuitton Torii Pharmaceutical Citibank Private Bank Garibaldis on Presidio, Inc. Inc. Merchandise Mart Company Cloud 9 of St. Stephen’s Gay Men’s Health Crisis, Entendre Limited Properties, Inc. Waldman Bros. Church Inc. Frechette Family Foundation The Non Nobis Solum Theodore & Renee Weiler Colorscope General Maritime Gap Inc. Foundation, Inc. Foundation, Inc. Columbia University Corporation Jean Paul Gaultier Park Place Motorcars Williams-Sonoma, Inc. Common Cents New York, George Little Management, Gilead Sciences, Inc. Adolph and Ruth Anonymous Inc. Inc. The Hagedorn Fund Schnurmacher Community Foundation of GES Exposition Services The Helene Foundation Foundation, Inc. New Jersey A Global Cause, A Global Company

ajor corporations routinely support charitable causes, but it takes the dedication of individuals such as Hewlett- Packard’s Satjiv S. Chahil to champion particular causes, such as AIDS research. Chahil, senior vice president of global marketing for HP, has been a driving force behind HP’s generous support of amfAR at its San Francisco Fall Gala and Cinema Against AIDS Cannes benefit events. “It’s a global cause, and HP is a global company,” said MChahil. But for Chahil, personal experience lies at the root of his commitment. In the 1980s, when HIV/AIDS was “still a whisper; people weren’t saying it publicly,” a key member of Chahil’s

amfAR Annual Report 2007 team at a previous job “withered away because of AIDS.” “We all experienced that firsthand; a whole group of contributors to our industry had been affected with that one experience,” said Chahil. “When something happens so close to you, it always has a more profound impact, and unless you are totally unfeeling, you need to do something about it.” Satjiv S. Chahil, vice As a member of an industry that relies on innovative technology, Chahil was quick to see the president of global market- value of supporting amfAR’s innovative research. His dedication to raising funds for HIV/AIDS ing for Hewlett-Packard’s research was further influenced “by the passion of the people driving the cause,” notably Sharon Personal Systems Group, Stone and Dame Elizabeth Taylor. “When the activities are done by people with so much commit- 36 supports amfAR’s ment and sense of purpose, it inspires others to be for the cause,” he said. Giving innovative research Additionally, Chahil considers it good business to support a cause that is so important to HP’s through corporate giving. key customers, ranging from the entertainment industry to the healthcare and pharmaceutical industries. At times he has reached into his own pocket in order to bolster a particular charitable venture. Chahil believes that if you are passionate about supporting worthwhile causes, the act of corporate philanthropy becomes much more than just a business transaction. This philosophy would surely be embraced by founder Dave Packard, who 40 years ago said that simply writing a check does not end one’s responsibility to a cause. “If you do something as part of your job, it is nine to five,” said Chahil. “But if you do it as part of a cause, you never once look at the clock.”

“If you do something as part of your job, it is nine to five. But if you do it as part of a cause, you never once look at the clock.” Gess Donor Fund of the Jones Apparel Group USA, Medco Health Renaissance, Inc. The T. Rowe Price Program Combined Jewish Inc. Mediavast Richmond American Homes for Charitable Giving Philanthropies Kareli Authors, Inc. Medical Management River Watch Restaurant, Inc. T101 Limited GFI Group Kenneth Cole Productions Solutions, LLC Roche Tailored Benefits GiftBeat Foundation Mellon Bank, N.A. Roman, Inc. Taryn Rose International Gilbert Displays, Inc. Kenneth Ludwig Home Merchandise Mart The Ronson Family Toyota Motor Sales, U.S.A., The Gill Foundation Furnishings, Ltd. Properties, Inc. Philanthropic Fund Inc. Global Health Strategies Key Foundation Mill Management, Inc. Roost Universal Studios, Inc. The Joseph Gluck Kikkerland Design Inc. Mission Fish Rosalie and Friends, Inc. Urban Studio LLC Foundation Klasse Company, Inc. Missoni USA The Rosenberg Group The Veneman Group Gochnauer Family Kline Family Foundation Moda Dora Gift and Home The Norman & Constance Vera Bradley Designs, Inc. Foundation Klub Services, Inc. Ltd. Sadek Foundation, Inc. Bridal House, Moe Greendale Family KPFF, LLC The Morris Foundation, Inc. Sales Producers, Inc. Ltd. Foundation, Inc. Krause Advertising The Morse Family Samsara Foundation VEST & Associates The Niki and Joe Gregory Land America Foundation, Inc. The Sawyer Family Fund Village Capital Inc. Charitable Foundation Larry L. Luing Family NARS Cosmetics, Inc. George H. Scanlon Vincini SpA Mimi & Peter Haas Fund Foundation National Society of Foundation Ellen M. Violett and Mary Annual Report 2007 amfAR Hamlin Capital Legend Merchant Group, Collegiate Scholars at the Shimoda Design Group P.R. Thomas Foundation Management Inc. University of Wisconsin– The Susan Stein Shiva Washington Mutual Bank 37 Hermes of Paris, Inc. Lenore Hecht Foundation, Madison Foundation We All Have AIDS Samuel and Hannah Inc. NATIXIS Silver Lake Technology Western Exhibitors, Inc.

Holzman Trust Bernard Lewis Charitable NCH Corporation Management, LLC William Morris Agency Giving Home Box Office Foundation New Prospect Foundation Sixt GmbH & Co. Winfield Foundation Hover Family Trust L’Oreal USA, Inc. Adina Marta Newman Fund Edward C. Smith Charitable The Marilyn and William The Iacocca Family Lucasfilm Foundation Newmark & Company Annuity Trust Young Charitable Foundation Lynn Mitchell Group, Inc. Old South Lighting The M & H Sommer Foundation ICI Worldwide, Inc. Magna Carta Foundation OneCoast Network Foundation Youngblood Ltd. Imtech Graphics Inc. The Robert Mapplethorpe O’Neil Industries, Inc. Sony BMG Zagwear, Inc. Iron Mountain Film and Foundation and Studio Plasmanet, Inc. Sorenson-Pearson Family Zarathustra Music, Inc. Sound Archives Mark Krueger & Associates, The Foundation Foundation, Inc. Anonymous (2) J.C. Edward Corporation Inc. Premiere Radio Networks Sotheby’s International Margaret G. Jacobs The May Foundation The Louis and Harold Price Realty Charitable Trust The Stephanie and Carter Foundation Jean L. & Robert A. Stern Carl Jacobs Foundation McClelland Foundation The Richard and Ann J. Foundation The Nathan P. Jacobs The Eugene McDermott Prouty Foundation Studios International Foundation Foundation R. Brant Design Swartz Family Foundation Jeffers Design Group John L. McHugh Reed Business Information Gertrude W. and Edward M. Jenny Hammons/Company Foundation, Inc. Reed Family Foundation Swartz Trust IN-KIND CONTRIBUTIONS

In-kind contributions of goods and services—either donated or discounted—are a mainstay of amfAR’s highly successful benefit events. Ranging from small cocktail parties and store openings to art auctions and international galas, these events play a critical role in raising vital funds and building AIDS awareness. amfAR relies on generous contributions by individuals and organizations of in-kind gifts ranging from design and printing of invita- tions and other materials, catering and beverage services, to auction and gift bag items, floral arrangements, entertainment, and more. amfAR extends grateful thanks to Kenneth Cole Productions for its many in-kind contributions, including Kenneth Cole products for meetings and conferences, and to American Airlines for the generous donations of air transportation and related services that allow the Foundation to keep travel expenses to a minimum. Since the early days of the epidemic, the art community has supported the fight against AIDS with steadfast generosity. amfAR is

amfAR Annual Report 2007 especially grateful to the many artists, galleries, and museums that have contributed to the resounding success of Two by Two for AIDS and Art, an annual dinner and auction of works by renowned contemporary artists that benefits amfAR and the Dallas Museum of Art. Graciously hosted each year by Howard and Cindy Rachofsky, Two by Two for AIDS and Art has raised a total of $17 million for amfAR and the Dallas Museum of Art since its inception in 1999. We thank the following donors for their charitable in-kind donations.

ART COMMUNITY Betty Cunningham Gavin Brown’s enterprise Knoedler & Co. Nic Nicosia IN-KIND Danese Gerald Peters Gallery David Kordansky David Noonan 38 303 Gallery Christian Dell Gladstone Gallery Uwe Kowski Adam Ogilvie

Giving John Adelman Nick Dine Goff + Rosenthal Barney Kulok Olafur Eliasson, Werkstatt Ameringer & Yohe Tomory Dodge Gorham Manufacturing Sean Landers & Büro Andrea Rosen Gallery Doner Studio Company Ricardo Lanzarini Jules Olitski Angstrom Gallery Michele Oka Doner April Gornik D’Nell Larson Tom Orr Anthony Meier Fine Arts Donzella Bob Gramsma Darryl Lauster PaceWildenstein Anton Kern Dune Anthony and Linda Grant Barry Le Va Carolanne Patterson Nobuyoshi Araki Dunn & Brown Greenberg van Doren Jody Lee Philip Pearlstein Estate of Diane Arbus Contemporary Gallery Nikki S. Lee Adam Pendleton Architectural Arts Company David Dupuis Isca Greenfield-Sanders Lehmann Maupin Gallery Emilio Perez Hope Atherton Edward Tyler Nahem Fine Theresa Hackett Janaki Lennie Perry Rubenstein Gallery Barry Whistler Gallery Art Trenton Doyle Hancock José Lerma Danica Phelps Marc Baseman Olafur Eliasson Mark Handforth Leslie Tonkonow Artworks Monica Pierce Michael Bell-Smith Elizabeth Dee Gallery Haswellediger & Co. Gallery + Projects John Pomara Bellwether Derek Eller David Hockney Arik Levy R 20th Century Andrew Bennett Tracey Emin Nir Hod Miranda Lichtenstein Robert Rauschenberg William Betts Emily Eveleth Holly Johnson Gallery Siobhan Liddell Jim Richard bitforms Brian Fahlstrom Jenny Holzer Justin Lieberman Road Agent Bortolami Dayan Patrick Faulhaber Tony Horton Luhring Augustine Sergio Rodrigues Bradly Brown Mark Ferguson Hosfelt Gallery Eva Lundsager Susie Rosmarin Jeff Burton Thomas Flechtner Jacqueline Humphries Magen H Gallery Johnnie Winona Ross James Lee Byars Mark Flood Pierre Huyghe Marco Maggi Michal Rovner Kristin Calabrese Florence Lynch Gallery Warren Isensee Marc Foxx Runyon Fine Arts, Inc. Ingrid Calame Fort Street Studio, Brad Jack Shainman Gallery Marian Goodman Gallery Ed Ruscha Scott Calhoun Davis, and Janis Provisor James Cohan Gallery Marianne Boesky Gallery Lisa Sanditz Douglas Leon Cartmel Foxy Production Bill Jensen Marty Walker Gallery Sara Meltzer Gallery Justin Carun Fraenkel Gallery Jewelers’ Werk Galerie Dan McCarthy Derrick Saunders Casey Kaplan Fredericks & Freiser John Berggruen Gallery Metro Pictures Gallery Christoph Schmidberger John Chamberlain Stephen Friedman John Connelly Presents Michael Werner Gallery David Schnell Charles Cowles Gallery Tom Friedman Mado Jolain Jason Middlebrook Björn Schülke Cheim and Read Friedrich Petzel Gallery Otis Jones moniquemeloche gallery Jeff Scott Theresa Chong Galerie Eigen + Art Josee Bienvenu Sarah Morris Sean Kelly Gallery Collage 20th Century Galerie Karsten Greve Oliver Kamm Moss Marco Boggio Sella Classics Galerie Lelong Seydou Keita Ted Muehling Richard Serra Phil Collins Tim Gardner Ted Kincaid Mulcahy Modern Cindy Sherman CRG Gallery Anna Gaskell Per Kirkeby Nicole Klagsbrun Gallery Gary Simmons Allison V. Smith “Over time we John Holt Smith Ken Solomon Sonnabend have really come John Sparagana Sperone Westwater to understand Mart Stam Steuben Glass Zoe Strauss amfAR’s critical Donald Sultan Sarah Sze role in the fight Taka Ishii Gallery Tanya Bonakdar Gallery against AIDS.” Sam Taylor-Wood Juergen Teller Ryan Trecartin and Lizzie Fitch Richard Tuttle Lane Twitchell Lesley Vance Charline Von Heyl Michael Wetzel Dallas art patrons Cindy and Howard Rachofsky have helped raise White Cube $8.5 million for amfAR through their generous support of the Rachel Whiteread Christopher Williams charity event Two by Two for AIDS and Art, which they have Grant Worth hosted since 1999. Yvon Lambert New York Zach Feuer Gallery Xiaoze Zie Andrzej Zielinski Jeff Zimmerman On the Cutting Edge of AIDS and Art Zwirner + Wirth Annual Report 2007 amfAR David Zwirner n 1999, amfAR began teaming up with the Dallas Museum of Art for a joint 39 General In-Kind A Gourmet’s Pantry fundraiser called Two by Two for AIDS and Art, an event designed to rally con- Aaron Barak temporary art lovers to raise funds for both cutting-edge HIV/AIDS research and Giving Abigail’s Adios Golf Club for the museum. When hedge fund investor and art collector Howard Rachofsky Aiden Gray and his wife, Cindy, were asked to host the event at their Richard Meier-designed Alba Interiors Alberta Ferretti home, they were happy to oblige. Alessandro Dell’Acqua Nearly a decade later, the black-tie dinner and art auction has evolved into Joshua Alexander, CMT American Airlines Ione of the city’s premier social events and amfAR’s highest-grossing domestic fundraiser, Lee and Penny Anderson generating $8.5 million for amfAR since its inception. Ann Gish Area San Francisco “We were introduced to amfAR when we were asked to host the first event in 1999,” Armani Casa said Cindy. “We were obviously aware of amfAR’s mission, but over time have really come Arte Italica Arteriors Home to understand its critical role in the fight against AIDS.” Aspen “Maybe we thought it would be a one-time event,” remembered Howard, “but when Azzaro Bag, Borrow, or Steal they asked if we would be willing to do it again, well, we thought it would be fabulous. The Bailey Street cause is good, the plan is cogent, and it’s a wonderful opportunity.” Barbara Cosgrove Lamps Barneys New York The Rachofskys generously volunteer their efforts in coordinating Two by Two’s local Bass/Chiarello leadership, assembling a roster of in-kind donors, and, above all, procuring significant Bayonne Golf Club Beatriz Ball contemporary artwork for auction. Infused with their energy and passion, Two by Two has Beauchamp Communications evolved from a one-night fundraiser to a week of events, including an exclusive Saturday Bella Rose by Chateau Bentley Dallas night black-tie dinner and auction, after-party, and a Sunday awards brunch where Berkeley Hotel amfAR presents its Award of Excellence for Artistic Contributions to the Fight Against AIDS. Bernardaud The Biltmore Hotel “It just made sense to support amfAR, and it quickly caught on,” said Cindy. “It Bing Bang certainly has opened the eyes of many people in our community.” Black Pearl bliss BMW Domain Home Fashions Jardinière National Golf Links of Sebonic Golf Club Bold Films Donna Karan Jean Paul Gaultier America Monica Seles Bonnie Fratis & Associates Jason Dorn Jeanine Payer Nautica Serendipity 3 Boor Bridges Architecture Dubai Duty Free Jeffrey Atlanta New York NDI Sergio Rossi Boucheron Duran Duran Joanne & Company Neiman Marcus Shear Bliss Bougainvillea Bob Egan John Dellaria Salon Lowell Nesbit Sheila Kelley’s S Factor Boulevard Eileen Fisher John Kane New York Knicks Hannah and Samuel Shipley BR Guest Restaurants El Raigon Argentine Asado John Varvatos Enterprises Daniel Nicoletta Kimora Lee Simmons Bradford Renaissance Elie Saab Jovovich-Hawk Sarah Nix Smart Workout Portraits Emanuel Ungaro JP Morgan Chase Private Nobu Fifty Seven Smorgas Chef Restaurants Stephen Brady Airlines Bank Nobu Miami Beach Sony/BMG Music Brick Restaurant Molly and Gregg Engles Judith Leiber Notre Monde Entertainment Romero Britto Enid Alvarez Photography Jumeirah NY Fitness South of France Brooklyn Style Foundation and Design Jane Kaplowitz Oakley John Eric Sparacio Brooks & Ian Etro and Echo Design Kauri Cliffs Lodge and Old World Designs Stella McCartney BRP Group Golf Course, Kerikeri, Olivia Riegel Mr. and Mrs. Spook Stream Todd Buchanan Excalibur New Zealand Oracle Fountains Style Paris Bulgari Facestation Kiehl’s Since 1851 Orla Kiely stylicon Bungalow Michael and Barbara Faure Kenneth Cole Productions Orlandi Sunset Tower Hotel

amfAR Annual Report 2007 Bungalow 8 Fendi Kiton Padmas Plantation Superdeluxe Burj Al Arab Feraud Kramer Photography Palecek TAG Sarah Ferguson, Duchess La Dolce Vita Paper Rad Mario Testino Candle Stick of York Ladybug Paul Smith Michael Tilson Thomas Carbon De Luxe Fine Art Lamps Lafayette 148 New York Peninsula Humane Society Tinicum Civic Association Cartier SA Fine Lines Co. LAFCO New York Perilla Tivol Studios Casa del Bianco Floreal, Inc. LALIQUE Peter Som Todd Event Design Casa Tua Fosters Point Landor Associates Pierre Olivier Deschamps Duane Tollison DJ Cassidy Four Hands Laso Group Tommy Toy’s Cuisine Chaiken Four Seasons Hotel, Alberto and Consuelo PlumpJack Chinoise Chanel San Francisco Lataliste Postrio Toss Designs The Chef’s Table Fragments The Late Show with David Pout Travel Planners Chelsea Eye & Cosmetic Frédéric Fekkai Letterman Handbag Tres Agaves Mexican Surgery Associates Fresh @ Ruby Skye Lauren Merkin Pratesi Kitchen & Tequila Lounge 40 Chez Panisse Restaurant Frette L’Ermitage Progress Trump International Golf Giving and Café Fusion Z Leslie Street Project Runway Club Chopard & Cie SA Gallery Designs Ed Libby The Rainbow Room TUMI Chopra Spa Holly Getty Tom Lieber Ralph Lauren Turner Sports Broadcasting Christian Dior Gianfranco Ferre LightenUp Designs Random Autograph Tzell Travel Giuseppe Cipriani Gianni Versace SpA William E. Little, Jr. Raquels Collection Until There’s A Cure Clayton Brothers Givenchy Livia Dumoulin Brett Ratner Uttermost Coach GoGo Gear Lois Lane Travel Robert Rauschenberg Valentino The Colbert Report Grey Gardens Loloi Rugs Redtoenails Vice Versa Mary Colhoun Gucci Longchamp USA Reinstein/Ross Victoria’s Secret Collections West Hal Boyer Louis Vuitton Hans Reiser, MD Corporation Company C The Halcyon Company Luca Luca Richard Cohen, Inc. Vietri Compass Home Rich Hamilton M∙A∙C Cosmetics Riley James Vikram Chatwal Hotels Completely Bare Spa Hammons Magnolia Casual Pat Riley Village Divers The Container Store Hampton Pet Carriers Mainly Baskets Rittenhouse Vintage Verandah Corona Décor Pamela Hanson Manolo Blahnik The Ritz-Carlton, San Visual Comfort Crabtree & Evelyn Harry Winston Marc Jacobs Francisco Walnut Street Theatre Currey Hayden Harnett Marchesa Robert Marc Opticians Gemma Ward Cyan Design Tim Headington Marco Polo Designs Vincent A. Roberti Waterford Dallas Market Center Hedges Mariana Roberto Cavalli William Wegman Daniel Perry Studios Hen-Feathers David McShane Rock & Republic Janet Weiner Daniel Stuart Hermes Mecca Rodarte The Weinstein Company Danube Restaurant Hewlett-Packard Company Men’s Youth Skincare Rollins Jamaica Well Box The Davenport Roadhouse Homestead General Store Mexico Boutique Hotels Michele Rollins Williams-Sonoma Home at The Cash Store Hotel (The Mercer) Michael Kors Sabine Römer Steven Witkoff Dean Hotel Bel-Air MiMa by Eurofly Rob Rosenbluth and Frank Yamrus, Gregory Lind Decorize Hotel Villa d’Este Liza Minnelli Carolyn Bernstein Gallery Delfina Restaurant Hugo Boss Kylie Minogue Rug Market Yves Saint Laurent DEMDACO The Huntington Hotel and Missoni Safari Zac Posen Department 56 Sales, Inc. Nob Hill Spa Moët Hennessy San Francisco Symphony Durwood Zedd Diane Von Furstenberg IMAX Morgans Hotel Group Sand Castle Winery Zodax Diesel IMG Morton’s Steakhouse Sapa Zuni Café The Dining Room at the Indian Springs Resort MTV Networks Saro Trading Company Ritz-Carlton, San Francisco and Spa The Myriad Restaurant Savim USA/Fornasetti diPietro Todd Salon The Institute for Culinary Group Julian Schnabel Dolce & Gabbana Education Napa Home & Garden Seasonal Living A Landmark Bequest

hose who knew philanthropist Ric Weiland well may not have been surprised to learn that his will included generous provisions for his favorite chari- table causes. But few could have anticipated that, upon his tragic death in 2006, Weiland would leave $8 million to amfAR. The bequest will be paid out through install- Tments over the course of the next eight years, providing a stable funding stream that allows amfAR to respond to emerging challenges in the HIV/ AIDS epidemic with speed and flexibility. Weiland joined his high school classmates and Paul Allen in 1975—the year they founded Microsoft—and became one of the software company’s first five employees. He worked as a project leader, lead program- mer, and developer for Microsoft’s BASIC and COBOL personal computing interfaces. He left Microsoft in 1988 and began to devote his energies to charitable work. Rather than start his own foundation, he chose instead to give tens of millions of dollars to various organizations. Weiland carefully reviewed

the programs and finances of the charities he chose to support and resisted Annual Report 2007 amfAR public acknowledgment of his generous giving. 41 “For many years Ric Weiland was one of amfAR’s most generous and knowledgeable individual donors,” said amfAR’s CEO, Kevin Robert Frost. Giving “His dedication and commitment to our work in ending the global AIDS epidemic was an inspiration to us all.” Weiland died in June 2006 at the age of 53, after a long battle with depression. The bulk of his estate went to establish the Weiland Designated Fund, to be managed by the Seattle-based Pride Foundation, with $65 mil- Philanthropist Ric Weiland—one of lion allocated to a group of national gay rights and HIV/AIDS organizations. Microsoft’s first five employees— “Ric wanted to be sure that his contributions would be used bequeathed $65 million to national gay effectively and efficiently to help improve and extend lives—in amfAR’s rights and HIV/AIDS organizations, case, the lives of people living with HIV/AIDS,” said Frost. “As a donor to including $8 million to amfAR. amfAR, Ric gave both with his head and with his heart.”

“Ric wanted to be sure that his contributions would be used effectively and efficiently to help improve and extend lives—in amfAR’s case, the lives of people living with HIV/AIDS.”

PLANNED GIVING

Planned, or deferred, giving is a farsighted investment in the future. Generous bequests and other planned gifts help ensure that amfAR can sustain its support of innovative HIV/AIDS research programs over the long term. Between October 2006 and September 2007, the Foundation was the grateful beneficiary of the planned gifts listed below, including particularly generous legacies from Gertrude Horowitz, Marie Eliopoulos, Martin F. and Irene R. Murphy, and Lorraine E. Cantor.

amfAR received gifts from the estates of

Maureen E. Bacchi Jean Eastman Jerome H. Lever Jannette Powell Michael F. Bennett Marie Eliopoulos Ralph A. Ludlow James Michael Rampe Mary G. Brakefield Lillian and Frank Fields David Edward MacArthur Peter P. Rossi Mildred Burg Jill & Jayne D. Franklin Galeb H. Maher Roberta Schecter Lorraine E. Cantor Edith Hollander Goldberg Francisco Martin Winifred E. Shaheen Herbert Chiltern Frank L. Gulizia Donna M. Mellem Joseph L. K. Snyder

amfAR Annual Report 2007 Gladys Chinn Gertrude Horowitz Dorothy Merdian Freda Sobel Marilyn Joyce Colbert Bertha M. Jacobson Michael Metzger Robert C. Tesch Frances M. Corrao Steven D. Kaeser Alice Ruth Meyer James Gordon Umberger Susan Ethel Cox Gertrude Kartzmer Margaret W. Midgett Richard W. Weiland Aileen Cramer Andrew Kott Joan Mills Miller Thelma and Clyde West John Perryman Davidson, III Olive M. Laubenthal May M. Moore Roy Glenn Wood Wilfred W. and Ruth J. Davies Michael Le Clair Marice Murphy Claire E. Dick Robert C. Lees Martin F. & Irene R. Murphy

42 VOLUNTEER SUPPORT Giving amfAR’s Board of Trustees, Program Board, and Scientific Advisory Committee are composed entirely of individuals who generously volunteer their time, professional expertise, and financial resources to the Foundation’s benefit. These core volunteers span a range of backgrounds and areas of expertise and include scientists, physicians, academics, and business leaders. In some locales, notably Dallas, Philadelphia/Bucks County, and San Francisco, committed individuals have established volunteer steering committees and have organized benefit events that help attract new supporters and build awareness of amfAR’s work.

In addition, amfAR is fortunate to enjoy the support of many celebrities from the fields of art, fashion, film, music, haute cuisine, publishing, and television who generously donate their time and talents to the Foundation’s benefit events. amfAR is especially grateful for the dedicated support of its founding international chairman, Dame Elizabeth Taylor, and Sharon Stone, global fundraising chairman, who remain highly visible and effective spokeswomen for the Foundation.

For many years, amfAR has benefited enormously from the steadfast support of three unique volunteer organizations:

Concerned Parents for AIDS Research (CPFA) was created in 1989 by a group of parents who, spurred by Alison Gertz’s public revelation that she had AIDS, realized that young people everywhere were at risk. CPFA seeks to secure an AIDS-free future by funding basic biomedical and clinical research to develop a preventive vaccine and a cure for HIV/AIDS, and by working to raise AIDS awareness and encouraging parents to become actively involved in finding a solution to this public health crisis. Since its inception, CPFA has raised $4 million for AIDS research.

Gift for Life (GFL) is a nationwide group of volunteers from the gift, stationery, tabletop, and decorative accessories industries who raise funds for AIDS research and build awareness among friends and colleagues. Founded in 1992, GFL has generated more than $4 million in support of amfAR’s programs. The Bucks County Committee is part of the Greater Philadelphia community, which was among the first to respond to the AIDS crisis in this country. To date, these donors have contributed more than $4.5 million to amfAR, which the Foundation has used to provide grants and fellowships to 80 Philadelphia-area researchers.

CPFA Executive Peter Schauben Naomi Campbell Eva Mendes Board of Directors Gerry Seibel Tracy Chapman Liza Minnelli Andrea Acker Warren Shoulberg Don Cheadle Kylie Minogue Roberta Bogen Cathy Steel George Clooney Liam Neeson Ivy Duneier Paul Thompson Sofia Coppola Petra Nemcova Marjorie Emden Laura Van Zeyl Matt Damon Cynthia Nixon Carol Gertz Joyce Washnik Rosario Dawson Rosie O’Donnell Annie Gilbert Nancy Wolkow Harold Dieterle Orfeh Rosalind Glaser Thom Filicia Aishwarya Rai Dr. Andrew Lipschitz Bucks County Committee Andy Garcia Anthony Rapp Eileen Mitzman Randy Apgar Richard Gere Brett Ratner Lois Nipon Scott Bass Whoopi Goldberg Natasha Richardson Tina Simner Allen Black Elliott Gould Robert Rodriguez Rory Teitelbaum Bob Egan Greg Grunberg Kurt Russell Wendy Wetchler Sally and Richard Henriques Tim Gunn Greg Kammerer Jerry Hall Julian Schnabel GFL Board of Directors David Lewis Marcia Gay Harden Kyra Sedgwick Arun Agarwaal Jim McClelland Goldie Hawn Chloë Sevigny John Amiri David McShane Paris Hilton Garry Shandling Tabitha Bowling Lynn Miller Dennis and Victoria Duffy Hopper Liz Smith Sheila Charton Doug and Betsy Rendall Elizabeth Hurley Kevin Spacey Mary Liz Curtin Renny Reynolds Cheyenne Jackson Barbra Streisand Cole Daugherty Kenneth G. Schaefer Sir Elton John and David Furnish Sharon Stone Sharon Davis Sam and Happy Shipley Eve Jeffers Dame Elizabeth Taylor

Mike Dean Jack Staub Milla Jovovich Tracie Thoms Annual Report 2007 amfAR Debra Gold David Topel Nicole Kidman Stanley Tucci Lisa Goodman Fred White Beyoncé Knowles Dita Von Teese 43 Jenny Hammons Julian Lennon Gemma Ward Su Hilty Celebrity Volunteers Carey Lowell Kerry Washington Kathy Krassner Casey Affleck Diego Luna Sigourney Weaver Giving Terence Morris Ted Allen Harvey Weinstein David Moses Woody Allen and Soon-Yi Previn Sophie Marceau Robin Williams Michael Ruddell Kevin Bacon Jesse L. Martin Michelle Yeoh Jill Sands Ellen Barkin Jack McBrayer John Saxtan Mischa Barton Rose McGowan

WORKPLACE GIVING

Workplace giving programs allow donors to direct a percentage of each paycheck or a fixed dollar amount to amfAR. Among the many generous individuals who contribute in this way are federal employees and U.S. military personnel who make donations through the Combined Federal Campaign (CFC). amfAR is listed with the CFC as AIDS Research Foundation (amfAR), and our CFC designation number is 11996. amfAR is represented in the CFC by Community Health Charities, a federation of national health agencies. Other donors make their contributions through state and municipal employee campaigns, United Way “write-in” designa- tions, and independent corporate workplace giving programs. amfAR is deeply grateful to the companies and agencies that allow it to participate in their campaigns and to the many individuals who direct their workplace contribu- tions to the fight against AIDS. FINANCIAL SUMMARY

FROM THE TREASURER AND THE CHAIR OF THE FINANCE AND BUDGET COMMITTEE

The fiscal year ending September 30, 2007, was a period of solid growth and financial stability for amfAR, The Foundation for AIDS Research, and we are pleased to present a summary of the audited financial statements from this period. The Foundation was able to exceed its ambitious fundraising goal, generating a total of $23.8 million in public support and revenue—a 30 percent increase over the previous year. A low supporting services ratio—the ratio of fundraising and management expenses to total support and revenue—of 18.5 percent demonstrated a high degree of operating efficiency. Another key fiscal indicator, the program spending ratio, came in at a robust 76.9 percent—meaning that 76.9 cents out of every dollar spent was invested directly in vital program activities. The Foundation ended the year with an operating surplus of $4.8 million. This was largely the result of a resoundingly

amfAR Annual Report 2007 successful benefit events season, which generated an unanticipated 47 percent increase in revenues over the previous year. That funding surplus allowed amfAR the flexibility to move quickly in establishing two important new initiatives. The Mathilde Krim Fellowships in Basic Biomedical Research provide a much-needed funding stream for bright young scientists seeking innovative solutions to HIV/AIDS. And the MSM Initiative seeks to address and reverse the alarmingly high rates of HIV infection among men who have sex with men (MSM) in resource-limited countries. Moving from concept to funding in less than a year, amfAR was able to scale up these programs on short notice, and announced initial grants for both just a few months after the close of the fiscal year. In 2007, amfAR again met the stringent requirements of governance and financial accountability demanded by the Better Business Bureau’s Wise Giving Alliance and the federal government’s workplace fundraising program, the Combined Federal 44 Campaign, as well as many state employee workplace giving campaigns. Financial Summary A copy of the complete audited financial statements, prepared in accordance with generally accepted accounting principles for not-for-profit organizations as established by the American Institute of Certified Public Accountants, is available upon request from amfAR at 120 Wall Street, 13th Floor, New York, NY 10005, and can be accessed online at www.amfar.org.

Wallace Sheft, C.P.A. Michael J. Klingensmith Treasurer Chair, Finance and Budget Committee

Public Support and Revenue Expenses

Investment income Management and other revenue: 3.5% and general: 8.9% Government Fundraising: 14.2% funding: 17.3%

Contributions Program Services 79.2% 76.9% STATEMENT OF ACTIVITIES AND CHANGES IN NET ASSETS

For the year ended September 30, 2007

Public Support and Revenue Public support $7,155,947 Special events 9,741,974 Planned giving 1,947,199 Government funding 4,105,703 Investment income and other revenue 845,601 Total public support and revenue $23,796,424

Expenses Research $7,577,791 Global initiatives 2,585,001 Public policy 1,081,867 Education and information 3,366,625 Total program services $14,611,284

Fundraising $2,691,494 Management and general 1,696,126 Total supporting services $4,387,620

Total expenses $18,998,904

Annual Report 2007 amfAR Change in net assets 4,797,520 Net assets, beginning of year 15,168,021 45 Net assets, end of year $19,965,541

STATEMENT OF FINANCIAL POSITION

Financial Summary Assets Cash and investments $21,631,048 Pledges and receivables, net 1,624,941 Prepaid expenses and other assets 453,871 Merchandise inventory and donated assets 513,869 Furniture, equipment, and leasehold improvements, net 840,517 Total assets $25,064,246

Liabilities Accounts payable and accrued expenses $1,267,408 Grants and fellowships payable, net 1,835,159 Deferred support and refundable advances 1,429,967 Other long-term liabilities 566,171 Total liabilities $5,098,705

Net assets Unrestricted $14,848,535 Temporarily restricted 4,815,046 Permanently restricted 301,960 Total net assets $19,965,541 For complete audited financial Total liabilities and net assets $25,064,246 statements, visit www.amfar.org Leadership and Advisory committees

Board of Trustees TRUSTEES Edward L. Milstein Mario Stevenson, Ph.D. 2007 Co-Chairman Director, Center for AIDS Research Arlen H. Andelson Milstein Brothers Capital Partners Professor, Program in Molecular Chairman of the Board Andelson Properties New York, NY Medicine Kenneth Cole Los Angeles, CA University of Massachusetts Medical Chairman and Chief Executive Officer Natasha Richardson School Kenneth Cole Productions Harry Belafonte Actress Worcester, MA New York, NY President New York, NY Belafonte Enterprises, Inc. Vice Chairman New York, NY Vincent A. Roberti HONORARY TRUSTEES Patricia J. Matson Chairman and Chief Executive Officer amfAR Annual Report 2007 Senior Vice President, David Bohnett Palisades Media Corporation Mouna E. Ayoub Communications (emerita) Chairman New York, NY Paris, France ABC, Inc. David Bohnett Foundation New York, NY Beverly Hills, CA Allan Rosenfield, M.D. John F. Breglio, Esq. Dean and DeLamar Professor Paul, Weiss, Rifkind, Wharton & Vice Chairman Zev Braun of Public Health Garrison John C. Simons President and Chief Executive Officer Mailman School of Public Health New York, NY Managing Partner Braun Entertainment Group, Inc. Columbia University Corporate Fuel Partners, LLC Beverly Hills, CA New York, NY Robert L. Burkett New York, NY The Carmen Group Jonathan S. Canno Alan D. Schwartz Washington, D.C. Treasurer New York, NY President Wallace Sheft, C.P.A. The Bear, Stearns Companies, Inc. Michael Fuchs 46 Partner Donald A. Capoccia New York, NY New York, NY

Leadership and Advisory Committees Sheft & Co. Managing Principal and Founder Westbury, NY BFC Partners Diana L. Taylor Sandra Hernández, M.D. New York, NY Managing Director Chief Executive Officer Secretary Wolfensohn & Co. The San Francisco Foundation William D. Zabel, Esq. Jane Breckenridge Eisner New York, NY San Francisco, CA Senior Partner President Schulte Roth & Zabel, LLP The Eisner Foundation Kevin Wendle Sherry Lansing New York, NY Bel Air, CA Entrepreneur Chief Executive Officer/Founder New York, NY; Paris, France The Sherry Lansing Foundation Founding International Arnold W. Klein, M.D. Los Angeles, CA Chairman Professor of Medicine/Dermatology Dame Elizabeth Taylor, D.B.E. University of California, Los Angeles ADJUNCT TRUSTEES Jane F. Nathanson Actress Beverly Hills, CA Psychologist Bel Air, CA David E. Bloom, Ph.D. Chair, Jane and Marc Nathanson Michael J. Klingensmith Chair, Department of Population and Community Foundation Founding Chairman Executive Vice President International Health Los Angeles, CA Mathilde Krim, Ph.D. Time Inc. Harvard School of Public Health Adjunct Professor New York, NY Boston, MA The Rev. Dr. Randolph Nugent Mailman School of Public Health General Secretary (ret.) Columbia University Michele V. McNeill, Pharm.D. R. Martin Chavez, Ph.D. General Board of Global Ministries New York, NY Chairman Partner United Methodist Church McNeill Family Foundation Goldman, Sachs & Co. New York, NY Long Boat Key, FL New York, NY Pauline Phillips Richard H. Metzner Mervyn F. Silverman, M.D., M.P.H. Nationally Syndicated Columnist (ret.) Principal President Los Angeles, CA Metzner-Schneider Associates Mervyn F. Silverman Associates, Inc. Dallas, TX Crockett, CA Leonard Rabinowitz Vice Chair, Global Initiatives members Wafaa El-Sadr, M.D., M.P.H. President Committee Chief, Division of Infectious Diseases Studio CL Adeeba Kamarulzaman, M.B.B.S., Dawn Averitt Bridge Harlem Hospital Center Los Angeles, CA F.R.A.C.P. Founder Professor of Clinical Medicine and Professor The Well Project Epidemiology Michael D. Shriver Head of Infectious Diseases Unit Nellysford, VA Columbia University Co-Director, AIDS Policy Research Department of Medicine New York, NY Center University of Malaya Tim Brown, Ph.D. AIDS Research Institute Kuala Lumpur Senior Fellow, Population and Health Sherry Glied, Ph.D. University of California, San Francisco Malaysia Studies Professor and Chair San Francisco, CA East-West Center Department of Health Policy and Chair, Public Policy Committee Honolulu, HI Management Joel D. Weisman, D.O. David E. Bloom, Ph.D. Mailman School of Public Health Physician Chair, Dept. of Population and Alex Carballo-Diéguez, Ph.D. Columbia University Rancho Mirage, CA International Health Associate Professor and Research New York, NY Harvard School of Public Health Scientist Boston, MA HIV Center for Clinical & Behavioral Jennifer Kates, M.A., M.P.A. IN MEMORIAM Studies Vice President and Director, HIV Vice Chair, Public Policy New York State Psychiatric Institute Policy Sheldon W. Andelson, Esq. Committee New York, NY Kaiser Family Foundation Mrs. Albert D. Lasker Margaret (Peggy) Hamburg, M.D. Washington, D.C. Jonathan M. Mann, M.D., M.P.H. Vice President for Biological Programs Willard (Ward) Cates, Jr., M.D.,

Maxine Mesinger Nuclear Threat Initiative M.P.H. Patrick Chung-ki Li, M.B.B.S. Annual Report 2007 amfAR Peter Scott, Esq. Washington, D.C. President, Research Chief of Service Tom Stoddard Family Health International Department of Medicine 47 Chair, Research Committee Durham, NC Queen Elizabeth Hospital Mario Stevenson, Ph.D. Hong Kong SAR, China Global Fundraising Director, Center for AIDS Research R. Alta Charo, J.D. Chairman Professor, Program in Molecular Warren P. Knowles Professor of Law Kenneth H. Mayer, M.D. Medicine & Bioethics Professor of Medicine and Com- Sharon Stone University of Massachusetts Medical University of Wisconsin Law School munity Health School Madison, WI Brown University/The Miriam Worcester, MA Hospital amfAR AMBASSADORS Grant N. Colfax, M.D. Providence, RI Vice Chair, Research Director of HIV Prevention and Milla Jovovich Committee Research William E. Paul, M.D. Liza Minnelli Sherry Deren, Ph.D. San Francisco Department of Chief, Laboratory of Immunology Michelle Yeoh Director Public Health National Institute of Allergy and Institute for AIDS Research San Francisco, CA Infectious Diseases (NIAID) Advisory Committees Leadership and Center for Drug Use and HIV National Institutes of Health (NIH) Program Board Research Hoosen (Jerry) Coovadia, M.D. Bethesda, MD National Development and Research Victor Daitz Professor of HIV/AIDS Chair Institutes, Inc. Research Peter R. Staley Allan Rosenfield, M.D. New York, NY Doris Duke Medical Research Institute Founder & Editor Dean and DeLamar Professor Nelson Mandela School of Medicine AIDSmeds.com of Public Health Mathilde Krim, Ph.D., ex officio University of KwaZulu Natal Brooklyn, NY Mailman School of Public Health Adjunct Professor Congella Columbia University Mailman School of Public Health South Africa David Vlahov, Ph.D. New York, NY Columbia University Director New York, NY Carl W. Dieffenbach, Ph.D. Center for Urban Epidemiological Chair, Global Initiatives Director, Basic Sciences Program Studies Committee Division of AIDS, NIAID New York Academy of Medicine Mervyn F. Silverman, M.D., M.P.H. Bethesda, MD New York, NY President Mervyn F. Silverman Associates, Inc. Crockett, CA BOARD COMMITTEES Scientific advisory Alan L. Landay, Ph.D. Management group committee Amy Lansky, Ph.D. Executive Committee Jeffrey Laurence, M.D. Kevin Robert Frost Kenneth Cole, Chair Mario Stevenson, Ph.D., Chair Michael Lederman, M.D. Chief Executive Officer Donald A. Capoccia Sherry Deren, Ph.D., Vice Chair Tun-Hou Lee, D.Sc. Michael J. Klingensmith Rafi Ahmed, Ph.D. Michael J. Leibowitz, M.D., Ph.D. Susan J. Blumenthal, M.D., M.P.A. Mathilde Krim, Ph.D. Angela Aidala, Ph.D. Carol Levine, M.A. Senior Policy and Medical Advisor Patricia J. Matson Jonathan S. Allan, D.V.M. Robert J. Levine, M.D. Wallace Sheft, CPA Katheryn Anastos, M.D. Judy Lieberman, M.D., Ph.D. Deborah C. Hernan John C. Simons Deborah Anderson, Ph.D. H. Kim Lyerly, M.D. Assistant Treasurer and Vice Allan Rosenfield, M.D. Warren A. Andiman, M.D. David M. Margolis, M.D. President, Public Information William D. Zabel, Esq. Peter S. Arno, Ph.D. Martin H. Markowitz, M.D. Julia Arnsten, M.D., M.P.H. Marta L. Marthas, Ph.D. Rowena Johnston, Ph.D. Audit Committee Larry O. Arthur, Ph.D. Kenneth Hugh Mayer, M.D. Vice President, Research Wallace Sheft, CPA, Chair Marcel A. Baluda, Ph.D. Justin C. McArthur, M.B.B.S., M.P.H. R. Martin Chavez, Ph.D. Robert B. Belshe, M.D. Joseph M. McCune, M.D., Ph.D. Jeffrey Laurence, M.D. John C. Simons Samuel A. Bozzette, M.D., Ph.D. Ian McGowan, M.D., Ph.D. Senior Scientific Consultant Jason Brenchly, Ph.D. Michael S. McGrath, M.D., Ph.D. Board Development Dennis R. Burton, Ph.D. A.D McNaghten, Ph.D. John F. Logan, Esq. Committee Salvatore T. Butera, D.V.M., Ph.D. John Gordon McNeil, M.D., M.P.H. Assistant Secretary, Vice President, amfAR Annual Report 2007 William D. Zabel, Esq., Chair Alex Carballo-Dieguez, Ph.D. Peter Messeri, Ph.D. and General Counsel Zev Braun David D. Celentano, Sc.D., M.H.S. Donna Mildvan, M.D. Jane B. Eisner Sarah H. Cheeseman, M.D. Christopher Murrill, Ph.D., M.P.H. Bill Melamed Arnold W. Klein, M.D. David B. Clifford, M.D. Jay A. Nelson, Ph.D. Vice President, Development Mathilde Krim, Ph.D. C. Budd Colby, Ph.D. Valerie Len Ng, Ph.D., M.D. Patricia J. Matson Grant Colfax, M.D. Nancy Padian, M.P.H., Ph.D. Scott Newman, M.B.A. Alan Schwartz Deborah Jean Cotton, M.D., M.P.H. Savita Pahwa, M.D. Assistant Treasurer and Vice Bryan Richard Cullen, Ph.D. Tristram G. Parslow, M.D., Ph.D. President, Finance and Compensation & Susanna Cunningham-Rundles, Jeremy Paul, Ph.D. Administration Organizational Ph.D. Matija Peterlin, M.D. Development Committee Richard Thomas D’Aquila, M.D. Anthony John Pinching, F.R.C.P., Monica S. Ruiz, Ph.D., M.P.H. John C. Simons, Chair John Delos DeLamater, Ph.D. D.Phil Acting Director, Public Policy Michael J. Klingensmith Roger Detels, M.D., M.S. William G. Powderly, M.D., 48 Richard H. Metzner Carl W. Dieffenbach, Ph.D. F.R.A.C.P.

Leadership and Advisory Committees Daniel C. Douek, M.D., Ph.D. Lynn Pulliam, Ph.D. Finance & Budget Committee D. Peter Drotman, M.D., M.P.H. Lee Ratner, M.D., Ph.D. Michael J. Klingensmith, Chair Frank Duff, M.D. Andrew Rice, Ph.D. Vincent A. Roberti Anke A. Ehrhardt, Ph.D. Melissa Robbiani, Ph.D. John C. Simons Homayoon Farzadegan, Ph.D. Yvonne J. Rosenberg, Ph.D. Dianne M. Finkelstein, Ph.D. Ruth M. Ruprecht, M.D., Ph.D. Fund Development Committee Jacquelyn H. Flaskerud, Ph.D. Travis Sanchez, D.V.M. Donald A. Capoccia, Chair Gerald Herbert Friedland, M.D. Frederick A. Schmitt, Ph.D. Jonathan S. Canno Richard Brian Gaynor, M.D. Gerald Schochetman, Ph.D. Edward L. Milstein Howard E. Gendelman, M.D. Robert Turner Schooley, M.D. Vincent A. Roberti Peter Ghazal, Ph.D Ola A. Selnes, Ph.D. William D. Zabel, Esq. Marya Gwadz, Ph.D. Ganes C. Sen, Ph.D. Nancy L. Haigwood, Ph.D. Frederick P. Siegal, M.D. Dean Hamer, Ph.D. Gail Skowron, M.D. Polly Harrison, Ph.D. Whaijen Soo, M.D., Ph.D. Sharon Hillier, Ph.D. James L. Sorensen, Ph.D. Charles H. Hinkin, Ph.D. Leonidas Stamatatos, Ph.D. Martin S. Hirsch, M.D. Simon Swingler, Ph.D. David Ho, M.D. Edward Elliot Telzak, M.D. Gary Norman Holland, M.D. Ernest F. Terwilliger, Ph.D. Thomas J. Hope, Ph.D. Gwen Van Servellen, R.N., Ph.D. Shiu-Lok Hu, Ph.D. Barbara Visscher, M.D., Dr.P.H. John Hylton, M.H.S., Ph.D. David Vlahov, Ph.D. David E. Kanouse, Ph.D. David J. Volsky, Ph.D. Ronald C. Kennedy, Ph.D. Bruce D. Walker, M.D. Vineet KewalRamani, Ph.D. J. Brice Weinberg, M.D. Robert Stephen Klein, M.D. Darrell P. Wheeler, Ph.D., M.P.H. Richard Kornbluth, M.D., Ph.D. Steven S. Witkin, Ph.D. Richard A. Koup, M.D. Peter R. Wolfe, M.D. Joan Kreiss, M.D., M.S.P.H. Richard T. Wyatt, Ph.D. Nathaniel R. Landau, Ph.D. ACKNOWLEDGMENTS

amfAR extends its grateful appreciation to William H. Byer, Variable Graphics LLC, for partial donation of the printing of this Annual Report.

PHOTO CREDITS

Page 2 Eric T. Michelson Page 3 Lawrence Switzer Page 6 Courtesy of Dr. Carolina Herrera; Piotr Bizior/SXC Page 7 Courtesy of Dr. Fong Siew Moy; Lawrence Switzer Page 8 © Les Cunliffe/Dreamstime.com Page 10 Jeff Vespa/WireImage Page 11 Courtesy of Dr. Ya-Lin Chiu Page 12 Courtesy of Dr. Robin Shattock Page 15 © Zol/Dreamstime.com Page 16 Sam Avrett Page 17 Courtesy of Dr. Pope Kosalaraksa Page 19 Karl Grobl Page 22 © Mike Rogal/Dreamstime.com; © Diadem Images/Dreamstime.com Page 24 Lawrence Switzer Page 25 Emily Byram Page 26 © Dmitriy Shironosov/Dreamstime.com Page 28 Courtesy of Dr. Peter Shalit Page 29 Kenneth Cole Productions Page 33 Dr. Rowena Johnston Page 36 Courtesy of Hewlett-Packard Page 39 Bruno Page 41 Courtesy of Stanford University Archives amfAR, The Foundation for AIDS Research, is a New York State not-for-profit corporation and is exempt from federal This Annual Report was produced by amfAR’s Public Information department: income tax under Section 501(c)(3) of the United States Internal Revenue Code Andrew McInnes, Group Director, Public Information (“the code”) and corresponding New Raoul Norman, Creative Director York Revenue and Taxation Code sections. Constance Herndon, Senior Staff Writer Contributions to amfAR are tax-deductible Carolyn Hanson, Staff Writer in accordance with the code. Winnie McCroy, Staff Writer Barbara Battle, Editorial Manager Yolande Hunter, Production Artist Natalie Jacobs, Assistant Coordinator amfAR meets the BBB Wise Giving Alliance’s Standards for Charity Accountability. AMERICAN AIRLINES is the official airline of amfAR. T H E F O U N D A T I O N F O R AIDS RESEARCH

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