Accelerated Brain Ageing and Disability in Multiple Sclerosis
bioRxiv preprint doi: https://doi.org/10.1101/584888; this version posted March 21, 2019. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under aCC-BY-NC-ND 4.0 International license. Title page Accelerated brain ageing and disability in multiple sclerosis Cole JH*1,2, Raffel J*3, Friede T4, Eshaghi A5,6, Brownlee W5, Chard D5,14, De Stefano N6, Enzinger C7, Pirpamer L8, Filippi M9, Gasperini C10, Rocca MA9, Rovira A11, Ruggieri S10, Sastre-Garriga J12, Stromillo ML6, Uitdehaag BMJ13, Vrenken H14, Barkhof F5,15,16, Nicholas R*3,17, Ciccarelli O*5,16 on behalf of the MAGNIMS study group. *Contributed equally 1Department of Neuroimaging, Institute of Psychiatry, Psychology & Neuroscience, King’s College London, London, UK. 2Computational, Cognitive and Clinical Neuroimaging Laboratory, Department of Medicine, Imperial College London, London, UK. 3Centre for Neuroinflammation and Neurodegeneration, Faculty of Medicine, Imperial College London, London, UK. 4Department of Medical Statistics, University Medical Center Göttingen, Göttingen, Germany. 5Queen Square Multiple Sclerosis Centre, Department of Neuroinflammation, UCL Institute of Neurology, London, UK. 6Department of Medicine, Surgery and Neuroscience, University of Siena, Siena, Italy. 7Research Unit for Neural Repair and Plasticity, Department of Neurology and Division of Neuroradiology, Vascular and Interventional Radiology, Department of Radiology, Medical University of Graz, Graz, Austria. 8Neuroimaging Research Unit, Department of Neurology, Medical University of Graz, Graz, Austria 9Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.
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