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PROGRAMME AND ABSTRACTS Welcome The biannual Molecular Microbiology Mee�ng seeks to unite scien�sts who study the molecular biology of microbes with a focus on prokaryotes and fungi. The Molecular Microbiology Mee�ng has previously been held five �mes at various loca�ons around Europe. In 2019 the mee�ng will be hosted by the Centre for Bacterial Cell Biology at Newcastle University, UK. The mee�ng will span two days and will be composed of both lectures and a poster session, allowing for PhD students, Postdoctoral Research Associates and Principal Inves�gators to present their work. Short talks will be selected from submited abstracts. Early career scien�sts are encouraged to apply. Please use the Hashtag #micronewcastle for posts and updates on Social Media. The Organising Commitee, Tracy Palmer, Jeff Errington, Henrik Strahl, Yulia Yuzenkova, Wendy Grunson, Stephanie Zuger-Legler and Heath Murray 2 | Page 6th Molecular Microbiology Meeting Newcastle upon Tyne Sponsors We would like to acknowledge the generous support of our sponsors: 3 | Page 6th Molecular Microbiology Meeting Newcastle upon Tyne Contents Welcome .............................................................................................................................................................. 2 Sponsors .............................................................................................................................................................. 3 Keynote Speakers ................................................................................................................................................ 5 General Information ............................................................................................................................................ 6 Conference venues .......................................................................................................................................... 6 Registration ..................................................................................................................................................... 6 Talks ................................................................................................................................................................. 6 AV facilities ...................................................................................................................................................... 6 Poster presentations ....................................................................................................................................... 6 Internet ............................................................................................................................................................ 6 Catering ........................................................................................................................................................... 6 Sponsor Exhibitions ......................................................................................................................................... 6 Conference dinner ........................................................................................................................................... 6 Maps .................................................................................................................................................................... 7 Useful Contacts .................................................................................................................................................. 10 Programme ........................................................................................................................................................ 11 Monday 17th of June ...................................................................................................................................... 11 Programme ........................................................................................................................................................ 13 Tuesday 18th of June ...................................................................................................................................... 13 Abstracts Oral Presentations ............................................................................................................................. 15 Abstracts Posters ............................................................................................................................................... 34 List of participants ............................................................................................................................................. 39 4 | Page 6th Molecular Microbiology Meeting Newcastle upon Tyne Keynote Speakers Susan Gotesman, Na�onal Ins�tutes of Health (USA) Tracy Palmer, Newcastle University (UK) Jeanna Salje, University of Oxford (UK) / Rutgers (USA) Tung Le, John Innes Centre (UK) Waldemar Vollmer, Newcastle University, UK Mar�n Thanbichler, Max Planck Ins�tute for Terrestrial Microbiology (DE) Esther Angert, Cornell University (USA) Morgan Beeby, Imperial Collage London (UK) Tanneke den Blaauwen, University of Amsterdam (NL) Manjula Reddy, Centre for Cellular & Molecular Biology (CCMB) (IN) Bert van den Berg, Newcastle University (UK) David Grainger, University of Birmingham (UK) 5 | Page 6th Molecular Microbiology Meeting Newcastle upon Tyne General Information Conference venues The conference will be taking place in the Catherine Cookson Building and the Baddiley-Clark building. The venues will be sign-posted. Registration The registration desk will be located next to the David Shaw Lecture Theatre in the Catherine Cook Building. Talks All talks will be held in the David Shaw Lecture Theatre in the Catherine Cookson building. A detailed schedule and titles are included in this booklet. AV facilities • Presenter PC with a standard set of software /HDMI cable to connect your personal device • Speakers to amplify any audio from the PC or your connected personal device • Widescreen (16:9) Digital display (this may either be a data projector or a large screen) Poster presentations The posters will be set-up in the Forum and the Seminar Room in the Baddiley-Clark Building. Internet Eduroam Visiting academics from participating institutions can use eduroam over wireless to login at Newcastle using their local Login Name and Password. Wireless Guest Service Visitors who are not able to connect to eduroam can use the free cloud WiFi network WiFi Guest to access the Internet using their own computer. Catering During the breaks there will be a tea/coffee buffet just outside the David Shaw Lecture Theatre. The lunch buffets will be in the Baddiley-Clark Building. Sponsor Exhibitions Our sponsors will set up stalls next to the David Shaw Lecture Theatre in the Catherine Cookson Building. Conference dinner The evening event will be held at the Wylam Brewery in Exhibition Park – a 10 minute walk from the main venues. 6 | Page 6th Molecular Microbiology Meeting Newcastle upon Tyne Maps FMS / CBCB FMS 7 | Page 6th Molecular Microbiology Meeting Newcastle upon Tyne 8 | Page 6th Molecular Microbiology Meeting Newcastle upon Tyne 9 | Page 6th Molecular Microbiology Meeting Newcastle upon Tyne Useful Contacts Newcastle University Webpage: www.ncl.ac.uk Institute for Cell and Molecular Biosciences Reception: 0191 20 83492 Organising Committee Email: [email protected] or [email protected] Online mapping: www.ncl.ac.uk/about/visit/maps Campus Security General: 0191 208 6817 Emergency: 0191 208 6666 City Information www.newcastlegateshead.co.uk National Rail Enquiries 08457 484950 / www.nationalrail.co.uk Newcastle International Airport 0871 882 1121 / www.newcastleairport.com 10 | Page 6th Molecular Microbiology Meeting Newcastle upon Tyne Programme Monday 17th of June 08:00–09:00 Registration 09:00–09:10 Welcome – Jeff Errington Session 1 Chair: Elisabeth Lowe 09:10–09:40 Tracy Palmer (Newcastle, UK) Genetic and biochemical analysis of the bacterial Tat system 09:40–09:55 Sam Hickman (Oxford, UK) Capturing protein transport in bacteria using ultra-long single-molecule tracking 09:55–10:10 Francesca Cianfanelli (Basel, CH) The PhoPQ two-component system enables Salmonella to adapt to tissue heterogeneity 10:10–10:40 Tanneke den Blaauwen (Amsterdam, NL) Periplasmic party 10:40–11:20 Coffee Session 2 Chair: David Bolam 11:20–11:50 Bert van den Berg (Newcastle, UK) Outer membrane nutrient processosomes mediate glycan uptake by the human gut microbiota 11:50–12:05 Paula Salgado (Newcastle, UK) S-layer structure and function in C. difficile 12:05–12:20 Marvin Gohrbandt (Osnabrück, DE) Partitioning of proteins into liquid-disordered domains in phase-separated in vivo plasma membranes of Escherichia coli and Bacillus subtilis 12:20–12:35 Rosalyn Leaman (York, UK) Illuminating the spatio-temporal dynamics of lipopolysaccharide in the Gram-negative bacterial outer membrane 12:35–12:50 Damon Huber (Birmingham, UK) Tale of a tail: how the C-terminal tail of SecA regulates its activity 12:50–14:00 Lunch 11 | Page 6th Molecular Microbiology Meeting Newcastle upon Tyne Session 3 Chair: Paula Salgado 14:00–14:30 Jeanne Salje (Oxford, UK/Rutgers USA) Peptidoglycan in obligate intracellular bacteria 14:30–14:45 Helene Botella (Imperial College, UK) Antibiotic tolerance in Mycobacteria 14:45–15:00 Emeline Lawaree (Oxford, UK) Impact of DNA ADP-ribosylation on DNA replication in enteropathogenic Escherichia coli 15:00–15:15
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