Using Multimodal MRI Techniques to Derive a Biomarker for Tracking The
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Addenbrooke's Cognitive Examination" As a Screening Test for Mild Cognitive Impairment in Hearing Impaired Individuals
Development and Validation of the “Addenbrooke’s Cognitive Examination” as a Screening Test for Mild Cognitive Impairment in Hearing Impaired Individuals Courtney North D.Clin.Psy. thesis (Volume 1), 2020 University College London 1 UCL Doctorate in Clinical Psychology Thesis declaration form I confirm that the work presented in this thesis is my own. Where information has been derived from other sources, I confirm that this has been indicated in the thesis. Signature: Name: Courtney North Date: 19th June 2020 2 Overview This thesis examined the utility of different neuropsychological tests in the detection of cognitive impairment in older adult populations. Limitations, directions for research and clinical implications have been highlighted. Part One: Meta-Analysis - The literature review sought to identify, for the first time, the cognitive tests that best discriminate between Posterior Cortical Atrophy (PCA) and typical Alzheimer’s Disease (tAD), as well as PCA and healthy controls (HC). The most discriminating cognitive tests for PCA and tAD presentations were found to be measures of perception and verbal memory. Part Two: Empirical Paper - The objectives were to develop a hearing-impaired version of the Addenbrooke’s Cognitive Examination (HI-ACE-III) and assess whether it can be used as a screening tool for mild cognitive impairment (MCI), as well as accurately distinguish cognitively impaired people from healthy controls. It was found to be a sensitive and specific screening tool, with a good ability to diagnose individuals with and without MCI in hearing-impaired populations. This was a joint project with Nattawan Utoomprurkporn, PhD student and qualified audiologist, and Mary Heatley, Trainee Clinical Psychologist Part Three: Critical Appraisal - The critical appraisal, considers the challenges of the project, including the barriers to recruitment, the navigation of the scientist- practitioner role and the impact of conducting research during a pandemic. -
Abstracts Presented at the International Neuropsychological
1 Abstracts Presented at the International Neuropsychological Society, the Swiss Neuropsychological Society (SVNP) and the German Neuropsychological Society (GNP) Meeting Zurich July 26-30, 2006 Zurich, Switzerland WEDNESDAY AFTERNOON, JULY 26, 2006 Symposium l/3:00-4:30 PM characterize pathology in patients with complex neuropsychiatric presentations. This part of the symposium will focus on providing specific examples of convergence in the data of diverse modalities in Using Neuropsychological, qEEG and SPECT Data the clinical care of refractory psychiatric patients. In our laboratories, to Direct Pharmacological and Neurosurgical we utilize a combination of tools in order to obtain converging data as Treatment in Refractory Psychiatric Disorders related to specific symptom clusters. We routinely use a combination of qEEG, evoked potentials, brain SPECT/PET, MRI/CT, and objective behavioral evaluation focusing on cognitive processes as Host: Angelos Halaris well as mood regulation. We developed a technique whereby we combine qEEG with SPECT/PET, which captures brain electrical activity as well as perfusion/metabolism, and correlate these profiles to structural features defined by MRI/CT. We have found that in many cases individual assessment modalities would not have sufficed M. PRIMEAU, C. BLODGETT DYCUS . Neuropsychological for appropriate interpretation of the data. Examples of diagnostic Evaluation as a Means to Direct Psychiatric Interve ntion. results, treatment decisions, and clinical outcomes will illustrate this Question: When is a psychiatrist like a blind man touching an principle. elephant? Answer: When the patient has a refractory psychiatric Correspondence: Angelos Halaris, M.D.,Ph.D. , APA, ACNP, disorder. Treatment targeted to a presenting symptom, such as Professor, Psychiatry and Behavioral Neurosciences, Loyola depression, may not be working because the patient’s condition is University Health System, 2160 S. -
Understanding Biological Psychology UBPA01 13/7/06 10:54 AM Page Ii
UBPA01 13/7/06 10:54 AM Page i Understanding Biological Psychology UBPA01 13/7/06 10:54 AM Page ii Basic Psychology This series offers those new to the study of psychology comprehensive, systematic and accessible introductions to the core areas of the subject. Written by specialists in their fields, they are designed to convey something of the flavour and excitement of psychological research today. Understanding Children’s Development Fourth Edition PETER K. SMITH, HELEN COWIE AND MARK BLADES Understanding Cognition PETER J. HAMPSON AND PETER E. MORRIS Understanding Abnormal Psychology NEIL FRUDE Understanding Biological Psychology PHILIP J. CORR UBPA01 13/7/06 10:54 AM Page iii Understanding Biological Psychology Philip J. Corr Department of Psychology University of Wales Swansea UBPA01 13/7/06 10:54 AM Page iv © 2006 by Philip J. Corr blackwell publishing 350 Main Street, Malden, MA 02148-5020, USA 9600 Garsington Road, Oxford OX4 2DQ, UK 550 Swanston Street, Carlton, Victoria 3053, Australia The right of Philip J. Corr to be identified as the Author of this Work has been asserted in accordance with the UK Copyright, Designs, and Patents Act 1988. All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means, electronic, mechanical, photocopying, recording or otherwise, except as permitted by the UK Copyright, Designs, and Patents Act 1988, without the prior permission of the publisher. First published 2006 by Blackwell Publishing Ltd 1 2006 Library of Congress Cataloging-in-Publication Data Corr, Philip J. Understanding biological psychology / Philip J. -
INS 2012 Fortieth Annual Meeting
Wednesday, February 15, 2012 i Final Program Fortieth Annual Meeting International Neuropsychological Society February 15-18, 2012 Montréal, Québec, Canada WEDNESDAY, FEBRUARY 15, 2012 9:00 AM–12:00 PM Wednesday Morning Continuing Education Courses Refer to CE Schedule for Location 12:00–4:00 PM Students of INS (SINS) Workshop: Writing Successful Grants in Neuropsychology Speakers: Mark Aloia, Rob Paul Verdun 1. ALOIA, MS Students of INS (SINS) Workshop: Writing Successful Grants in Neuropsychology 1:00–4:00 PM Wednesday Afternoon Continuing Education Courses Refer to CE Schedule for Location 4:15–5:45 PM Poster Session 1: Cognitive Rehabilitation/MS and Demylenation/Memory/Cross-cultural Salons Fontaine A and B Cross Cultural 1. ANDERSON, EC Written Expression Performance of Bilingual versus Monolingual College Students 2. BENNETT, J The Relationship Between Phonemic Fluency and IQ in Hispanic Bilingual Students 3. CROSSLEY, M The Northern Cultural Assessment of Memory (N-CAM): Normative Data from an Inner-city Clinic Supports Efficacy and Validity of a Cognitive Screen for Aboriginal Adults 4. JENKINS, JR Bilingual Proficiency and Contextual Memory Performance in a Hispanic Adult Sample 5. JOSHI, R Real-World Validity of Cross-Cultural Neuropsychological Testing: Cognitive Functioning and Occupational Level in India 6. LAU, KM Set-shifting, mental flexibility, and bicultural stress among Chinese American adults 7. MARTINEZ REYES, DA Monolingual and Multilingual Performance Differences on Tests of Unstructured Visuoconstruction Ability and Contextual Memory 8. RABIN, LA Trends in the Neuropsychological Assessment of Ethnic Minorities: A Survey of Neuropsychologists in the U.S. and Canada 9. RITCHIE, D Selection Criteria for Clinical Neuropsychology Internships 10. -
Addendum: Changes to the Program
Addendum: Changes to the Program The following changes to the program occurred after it was finalized. These changes will be included in an addendum to the Final Program in the Journal of the International Neuropsychological Society (JINS), Volume 20. The following abstracts have been rescheduled: WeDNESday July 9, 2014 2:00–3:30 PM Poster session 2: Attention, Autism, emotion, epilepsy, Genetics, laterality, Infectious Disease, Imaging, learning Disabilities, and Visuospatial Functions #32. KHeNTOV-KRAUS, l. Vowel letter Dyslexia. Moved to #41 in: Poster Session 3: Cognitive Intervention/Rehabilitation, executive Functions/ Frontal lobes, Memory Functions, and TBI (Thursday July 10, 10:30 AM–12:00 PM) 3:30–5:00 PM Paper session 6: Development and Genetics, Moderated by sarah Raz #4. ANAKI, D. Factors underlying Face and emotion Recognition in Women with Turner syndrome. Moved to #5 in: Paper Session 11: executive Functions, Moderated by yehuda Pollak (Friday July 11, 10:30 AM–12:00 PM) THuRsday July 10, 2014 10:30 AM–12:00 PM Poster session 3: Cognitive Intervention/Rehabilitation, executive Functions/Frontal lobes, Memory Functions, and TBI #10. HALLER, M. High Gamma Duration in Human Prefrontal Cortex Predicts Decision Time. Moved to #41 in: Poster Session 5: Assessment/Psychometrics/Methods, Cross Cultural, Drug/Toxin-Related Disorders, electrophysiology, Forensic Neuropsychology, Demyelinating Disorders, and Psychopathology/Neuropsychiatry (Friday July 11, 10:30 AM–12:00 PM) The following abstracts were withdrawn after being accepted for presentation: WeDNESday July 9, 2014 10:00–11:30 AM Poster session 1: Aging, Behavioral Neurology, Cancer, Dementia, and stroke/Aneurysm #10. AsGHAR, M. Potential role of grape powder in improving age-related decline in brain and kidney functions. -
Differentiation of Neuropsychological Features Between Posterior Cortical
Li et al. BMC Neurology (2018) 18:65 https://doi.org/10.1186/s12883-018-1068-6 RESEARCHARTICLE Open Access Differentiation of neuropsychological features between posterior cortical atrophy and early onset Alzheimer’s disease Jieying Li1,7, Liyong Wu1, Yi Tang1, Aihong Zhou1, Fen Wang1, Yi Xing1 and Jianping Jia1,2,3,4,5,6* Abstract Background: Posterior cortical atrophy (PCA) is a group of clinical syndromes characterized by visuospatial and visuoperceptual impairment, with memory relatively preserved. Although PCA is pathologically almost identical to Alzheimer’s disease (AD), they have different cognitive features. Those differences have only rarely been reported in any Chinese population. The purpose of the study is to establish neuropsychological tests that distinguish the clinical features of PCA from early onset AD (EOAD). Methods: Twenty-one PCA patients, 20 EOAD patients, and 20 healthy controls participated in this study. Patients had disease duration of ≤4 years. All participants completed a series of neuropsychological tests to evaluate their visuospatial, visuoperceptual, visuo-constructive, language, executive function, memory, calculation, writing, and reading abilities. The cognitive features of PCA and EOAD were compared. Results: All the neuropsychological test scores showed that both the PCA and EOAD patients were significantly more impaired than people in the control group. However, PCA patients were significantly more impaired than EOAD patients in visuospatial, visuoperceptual, and visuo-constructive function, as well as in handwriting, and reading Chinese characters. Conclusions: The profile of neuropsychological test results highlights cognitive features that differ between PCA and EOAD. One surprising result is that the two syndromes could be distinguished by patients’ ability to read and write Chinese characters.