View metadata, citation and similar papers at core.ac.uk brought to you by CORE World Journal of Surgical Oncology provided by PubMed Central BioMed Central Review Open Access Goblet cell carcinoid of the appendix Payam S Pahlavan*1 and Rani Kanthan2 Address: 1Department of Physiology and Pathophysiology, University of Heidelberg, Heidelberg, Germany and 2Department of Pathology, University of Saskatchewan, Saskatoon, Canada Email: Payam S Pahlavan* -
[email protected]; Rani Kanthan -
[email protected] * Corresponding author Published: 20 June 2005 Received: 16 February 2005 Accepted: 20 June 2005 World Journal of Surgical Oncology 2005, 3:36 doi:10.1186/1477-7819-3- 36 This article is available from: http://www.wjso.com/content/3/1/36 © 2005 Pahlavan and Kanthan; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: Goblet cell carcinoid (GCC) of the appendix is a rare neoplasm that share histological features of both adenocarcinoma and carcinoid tumor. While its malignant potential remains unclear, GCC's are more aggressive than conventional carcinoid. The clinical presentations of this neoplasm are also varied. This review summarizes the published literature on GCC of the appendix. The focus is on its diagnosis, histopathological aspects, clinical manifestations, and management. Methods: Published studies in the English language between 1966 to 2004 were identified through Medline keyword search utilizing terms "goblet cell carcinoid," "adenocarcinoid", "mucinous carcinoid" and "crypt cell carcinoma" of the appendix.