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School of Veterinary Medicine Date UNIVERSITY OF PENNSYLVANIA - SCHOOL OF VETERINARY MEDICINE DATE: November 2019 CURRICULUM VITAE Oliver A Garden BSc BVetMed PhD FRSA FCPP FHEA FRCVS DipACVIM DipECVIM-CA The Henry and Corinne R Bower Professor of Medicine Chair of the Department of Clinical Sciences and Advanced Medicine OFFICE ADDRESS: University of Pennsylvania School of Veterinary Medicine Matthew J Ryan Veterinary Hospital 3900 Delancey Street Philadelphia, PA 19104 EDUCATION: King’s College London, UK: Bachelor of Science (First Class), 1990, Pharmacology with Basic Medical Sciences Royal Veterinary College, UK: Bachelor of Veterinary Medicine (Distinction in Medicine), 1993: Veterinary Medicine and Surgery Royal Veterinary College, UK: Doctor of Philosophy (passed with no corrections), 1998: Gastrointestinal Immunology Imperial College London, UK: Certificate of Advanced Studies in Learning and Teaching, 2005: Further Education / Pedagogy POSTDOCTORAL TRAINING and FELLOWSHIP APPOINTMENTS: 08.01.93 – 08.01.94: Royal Veterinary College, UK Rotating internship, Department of Small Animal Medicine and Surgery 09.10.94 – 09.10.98: Royal Veterinary College, UK Wellcome Trust Clinical Research Training Scholarship: Combined clinical / PhD program funded by a personal Scholarship, with specialization in gastroenterology and immunology 11.01.98 – 07.01.99: University of South Carolina School of Medicine Wellcome Trust Research Training Fellowship: Postdoctoral program at Palmetto Richland Memorial Hospital, funded by a personal Fellowship 07.12.99 – 07.12.01: Cornell University Hospital for Animals, Ithaca, New York Residency in Small Animal Internal Medicine 08.03.01 – 08.15.04: Imperial College London, UK Wellcome Trust Advanced Fellowship: Postdoctoral program in the Department of Immunology, Division of Medicine, Hammersmith Campus, funded by a personal Fellowship PRIOR FACULTY APPOINTMENTS: All at the Royal Veterinary College, UK 08.18.04 – 11.12.11: Senior Lecturer in Internal Medicine 11.13.11 – 08.31.13: Reader in Internal Medicine and Immunology 09.01.13 – 12.02.16: Professor with tenure in Comparative Medicine and Immunology 1 HOSPITAL AND UNIVERSITY ADMINISTRATIVE APPOINTMENTS: Chairman of Departmental Safety Committee, Department of Immunology, Imperial College London, UK (2004 to 2008) Undergraduate Research Opportunities Program Coordinator, Department of Immunology, Imperial College London (2004 to 2008) London Technology Network Business Fellow, Department of Immunology, Imperial College London (2005 to 2007) Member of Genetically Modified Organisms Committee, Royal Veterinary College (RVC), UK (2008 to 2013) Chairman of Phase 3 Sub-Committee overseeing Intramural Clinical Rotations, Didactic Clinical Elective modules and Research Project 2, before its disbanding; RVC (2009 to 2011) Member of Learning, Teaching & Assessment and Course Management Committees, RVC (2009 to 2014) Director of Research Project 2 (Final Year Student Research Project), RVC (2009 to 12/2016) Director of Elective Teaching Program, RVC (2009 to 2015) Member of Quality Assurance and Enhancement Strategy Working Group, RVC (2011 to 2014) Academic Lead of the Oncology Special Interest Group (team of ~70 academics, including postdoctoral fellows and PhD students, with an interest in oncology), RVC (2012 to 12/2016) RESEARCH and/or CLINICAL INTERESTS: My research focuses on mechanisms of peripheral tolerance in health and disease, spanning the mouse, rat and dog as model species of both autoimmune disease and cancer. My work has interrogated the role of regulatory T cells and more recently myeloid-derived suppressor cells in this context. SPECIALTY CERTIFICATION: Royal College of Veterinary Surgeons (UK) Certificate in Small Animal Internal Medicine (September 1996) Diplomate of the American College of Veterinary Internal Medicine (Small Animal Internal Medicine) (July 2002) Diplomate of the European College of Veterinary Internal Medicine – Companion Animals (May 2003) Royal College of Veterinary Surgeons (UK) Specialist in Small Animal Internal Medicine (February 2016) LICENSURE: 07.27.93: Membership of the Royal College of Veterinary Surgeons (UK) 08.01.05: Fellowship of The Higher Education Academy (UK) 09.23.16: Fellowship of the Royal College of Veterinary Surgeons (UK) AWARDS AND HONORS: Undergraduate awards (BSc and BVetMed): Leaper Science Prize (1987), Frank Drury Anatomy Prize (1989), Tompson First Prize (1992), Centenary First Prize (1992) British Society for Immunology (BSI) Best Poster Prize (of >400 posters on display), Annual Congress, December 2-5, 2003, Harrogate: Monk, CR, Spachidou, M, Rovis, F, Lechler, RI and Garden, OA (2003) MRL/Mp CD4+CD25- T cells resist suppression by CD25+ Tregs in vitro: a defect of effector cells in lupus? Immunology 110 (S1): 81 ProImmune Ltd Poster Prize, BSI Annual Congress, December 2-5, 2003, Harrogate: Rovis, F, Lee, B, Lechler, RI and Garden, OA (2003) Murine CD4+CD25+ Tregs: towards the identification of molecular markers. Immunology 110 (S1): 119 Nature Immunology Poster Prize, The Third International Conference on Regulatory T Cells and Helper T Cell Subsets and Clinical Applications in Human Diseases, October 13-16, 2012, 2 Shanghai, China: Pinheiro, D, Pinney, JW and Garden, OA. A phylogenetic examination of regulatory networks within the Animalia Kingdom. The Kennel Club International Canine Health Award for research into canine health and diseases: May 2017 MEMBERSHIP in LEARNED / PROFESSIONAL SOCIETIES: Member and then Fellow, Royal College of Veterinary Surgeons: July 1993 to date Member and then Fellow, Royal Society of Biology: July 1990 to date Member, British Society for Immunology: August 2001 to date Member, Comparative Gastroenterology Society: June 2007 to date Member, European Society of Veterinary Oncology: February 2014 to date Fellow, The Higher Education Academy: August 2004 to date Fellow, The Royal Society of Arts, Manufactures and Commerce: January 2016 to date Fellow, The College of Physicians of Philadelphia: March 2019 to date PROFESSIONAL ASSOCIATIONS: Visiting Professor, Division of Immunology and Inflammation, Department of Medicine, Imperial College London, Hammersmith Campus, Du Cane Road, London, W12 ONN, UK (2002 to 2018) Visiting Professor, Centre for Haemato-Oncology, Barts Cancer Institute, School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London, EC1M 6BQ, UK (2013 to 2018) Adjunct Professor, Royal Veterinary College, University of London, NW1 0TU, UK (2016 to present) NATIONAL / INTERNATIONAL COMMITTEES AND ACTIVITIES: Reviewer for the Journal of Veterinary Internal Medicine, Veterinary Clinical Pathology, Veterinary Research, In Practice, Immunology, Clinical and Experimental Immunology, Arthritis Research and Therapy, American Journal of Transplantation (2002 to present) Grant reviewer for Biological and Biotechnology Science Research Council, Wellcome Trust, Medical Research Council Member of Steering Committee, Comparative Gastroenterology Society Biopsy Archive Project (2008 to 2015) Member and Angoff Study Participant, ACVIM Examination Rating Committee (2010 to 2014) Member of European Canine Lymphoma Network initiative (2013 to present) Chairman, European College of Veterinary Internal Medicine Clinical Studies Grant Fund (2016 to present) CLINICAL SERVICE at Queen Mother Hospital for Animals (Royal Veterinary College): Title of Years Number of Weeks/Month Number of Hours per week service Months on on Clinics Days on of direct student Clinics/year clinics per teaching contact Week while on clinics Small 12 3 4 5 (7 when on 12 Animal weekend duty, which Internal amounts to 8 Medicine weekends per year) In my current position as the Chair of the Department, I undertake 10 weeks of clinical service per year, as an internist in the Matthew J Ryan Hospital. 3 PUBLICATIONS: Peer-Reviewed Research Papers: IF = impact factor (when published) Garden, OA and Tuck, ME (1993) Tendon transposition in the surgical management of a soft tissue sarcoma of the limb. Veterinary Record 133: 621-623 [IF 1.50] Lamb, CR, Wrigley, RH, Simpson, KW, Forster-van Hijfte, M, Garden, OA, Smyth, JBA, Rutgers, HC and White, RN (1996) Ultrasonographic diagnosis of portal vein thrombosis in four dogs. Veterinary Radiology and Ultrasound 37(2): 121-129 [IF 1.06] White, RN, Trower, ND, McEvoy, FJ, Garden, OA and Boswood, A (1996) A method for controlling portal pressure after attenuation of intrahepatic portacaval shunts. Veterinary Surgery 25: 407-413 [IF 1.57] White, RN, Boswood, A, Garden, OA and Hammond, RA (1997) Surgical management of subvalvular aortic stenosis and congenital mitral dysplasia in a golden retriever. Journal of Small Animal Practice 38: 251-255 [IF 0.89] Polvi, A, Garden, OA, Elwood, CM, Sørensen, SH, Batt, RM, Maki, M and Partanen, J (1997) Canine major histocompatibility complex genes DQA and DQB in Irish setter dogs. Tissue Antigens 49: 236-243 [IF 2.33] Garden, OA, Rutgers, HC, Sørensen, SH, Daniels, S, Walker, D and Batt, RM (1997) Reference range and repeatability of a combined intestinal permeability and function test in Irish setter dogs. Research in Veterinary Science 63: 257-261 [IF 1.35] Garden, OA, Polvi, A, Houlston, RS, Maki, M, Batt, RM and Partanen, J (1998) Genetic susceptibility to dietary gluten sensitivity in Irish setter dogs is not linked to the major histocompatibility complex. Tissue Antigens 52: 1-7 [IF 2.33] Garden, OA, Manners, HK, Sørensen, SH, Rutgers, HC, Daniles, S,
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