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Rabbit Anti-HOXA6/FITC Conjugated antibody

SL11294R-FITC

Product Name: Anti-HOXA6/FITC Chinese Name: FITC标记的同源盒基因HOXA6蛋白抗体 HOX1B; Homeo box 1B; Homeo box A6; 1B; Homeobox A6; Homeobox Hox A6; Homeobox protein Hox-1B; Homeobox protein Hox-A6 antibody Alias: Homeobox protein HoxA6; HOX 1; Hox 1B; HOX1; HOX1.2; Hox1B; HOXA6; HX A6; HXA6; HXA6_HUMAN. Organism Species: Rabbit Clonality: Polyclonal React Species: Human,Mouse,Rat,Dog,Pig,Horse,Sheep, ICC=1:50-200IF=1:50-200 Applications: not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. Molecular weight: 23kDa Form: Lyophilized or Liquid Concentration: 1mg/ml immunogen: KLH conjugated synthetic peptide derived from human HOXA6/HOX1B (171-233aa) Lsotype: IgG Purification: affinitywww.sunlongbiotech.com purified by Protein A Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year Storage: when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. background: The Hox homeobox encode that are transcriptional regulators with an established role in embryonic development. HoxA6 (homeobox A6), also known as Product Detail: HOX1B, is a 233 amino acid protein that localizes to the nucleus. Expressed during embryonic development, HoxA6 functions as a sequence-specific DNA-binding that is part of a regulatory mechanism that provides cells with positional identities during development. Via its ability to bind DNA, HoxA6 plays an important role in the regulation of expression, as well as morphogenesis and differentiation. The gene encoding HoxA6 maps to human 7, which houses over 1,000 genes and comprises nearly 5% of the . Defects in some of the genes localized to have been linked to Osteogenesis imperfecta, Williams-Beuren syndrome, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.

Function: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

Tissue Specificity: Nucleus.

Similarity: Belongs to the Antp homeobox family. Contains 1 homeobox DNA-binding domain.

Database links:

Entrez Gene: 3203 Human

Entrez Gene: 15403 Mouse

Entrez Gene: 685732 Rat

Omim: 142951 Human

SwissProt: P31267 Human

SwissProt: P09092 Mouse Unigene:www.sunlongbiotech.com 679517 Human Unigene: 222030 Mouse

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.