Update on Tumor-Infiltrating Lymphocytes (Tils) in Breast Cancer
Seminars in Cancer Biology xxx (xxxx) xxx–xxx Contents lists available at ScienceDirect Seminars in Cancer Biology journal homepage: www.elsevier.com/locate/semcancer Review Update on tumor-infiltrating lymphocytes (TILs) in breast cancer, including recommendations to assess TILs in residual disease after neoadjuvant therapy and in carcinoma in situ: A report of the International Immuno- ☆ Oncology Biomarker Working Group on Breast Cancer ⁎ Maria Vittoria Diecia,b, , Nina Radosevic-Robinc,d, Susan Fineberge,f, Gert van den Eyndeng,h, Nils Ternesi,j, Frederique Penault-Llorcac,d,k, Giancarlo Pruneril,m, Timothy M. D’Alfonson, Sandra Demariao, Carlos Castanedap, Joselyn Sanchezp, Sunil Badveq, Stefan Michielsi,j, Veerle Bossuytr, Federico Rojos, Baljit Singht, Torsten Nielsenu, Giuseppe Vialev, Seong-Rim Kimw, Stephen Hewittx, Stephan Wienerty, Sybille Loiblz, David Rimmr, Fraser SymmansA, Carsten DenkertB, Sylvia AdamsC, Sherene LoiD, Roberto SalgadoE,F,G,on behalf of the International Immuno-Oncology Biomarker Working Group on Breast Cancer a Department of Surgery, Oncology and Gastroenterology, University of Padua, Padua, Italy b Medical Oncology 2, Veneto Institute of Oncology IOV – IRCCS, Padua, Italy c Department of Surgical Pathology and Biopathology, Jean Perrin Comprehensive Cancer Centre, Clermont-Ferrand, France d Inserm/University of Auvergne U1240, Clermont-Ferrand, France e Montefiore Medical Center, Bronx, NY, USA f The Albert Einstein College of Medicine, Bronx, NY, USA g Molecular Immunology Unit, Institut Jules Bordet, Université Libre de Bruxelles, Brussels, Belgium h Department of Pathology, GZA Ziekenhuizen, Antwerp, Belgium i Service de Biostatistique et d'Epidémiologie, Gustave Roussy, B2 M, RdC,114 rue Edouard-Vaillant, 94805, Villejuif, France j CESP, Fac. de médecine – Univ.
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