Anti-ITIH4 Monoclonal Antibody, Clone 8H20 (DMABT-H28055) This Product Is for Research Use Only and Is Not Intended for Diagnostic Use

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Anti-ITIH4 monoclonal antibody, clone 8H20 (DMABT-H28055) This product is for research use only and is not intended for diagnostic use. PRODUCT INFORMATION Product Overview Mouse Anti-ITIH4 Monoclonal Antibody Specificity Reacts with most HIV-1 Clade C gp120/gp160 proteins as tested. Minimal cross-reactivity to other subtypes. Target ITIH4 Immunogen Recombinant gp120 (Con_C/2006) protein (a.a. 34-518) Isotype IgG1 Source/Host Mouse Species Reactivity Virus Clone 8H20 Conjugate Unconjugated Epitope Conformational Epitope Size 500 μg Preservative None Storage Store at -20°C for long-term storage. Store at 2-8°C for up to one month. Avoid freeze/thaw cycles. GENE INFORMATION Gene Name ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4 [ Homo sapiens ] Official Symbol ITIH4 Synonyms ITIH4; inter-alpha-trypsin inhibitor heavy chain family, member 4; inter alpha (globulin) inhibitor H4 (plasma Kallikrein sensitive glycoprotein) , ITIHL1; inter-alpha-trypsin inhibitor heavy chain H4; H4P; IHRP; plasma Kallikrein sensitive glycoprotein; ITI heavy chain H4; inter-alpha-inhibitor heavy chain 4; plasma kallikrein-sensitive glycoprotein 120; inter-alpha-trypsin inhibitor, heavy 45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected] Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved chain-like, 1; inter-alpha-trypsin inhibitor family heavy chain-related protein; inter-alpha (globulin) inhibitor H4 (plasma Kallikrein-sensitive glycoprotein); GP120; PK120; ITIHL1; PK-120; ITI-HC4; DKFZp686G21125; Entrez Gene ID 3700 Protein Refseq NP_001159921 UniProt ID B7ZKJ8 Chromosome Location 3p21.1 Function endopeptidase inhibitor activity; serine-type endopeptidase inhibitor activity; 45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected] Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved.

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Frequent Expression Loss of Inter-Alpha-Trypsin Inhibitor Heavy Chain (ITIH) Genes in Multiple Human Solid Tumors: a Systematic Expression Analysis
Hamm, A; Veeck, J; Bektas, N; Wild, P J; Hartmann, A; Heindrichs, U; Kristiansen, G; Werbowetski-Ogilvie, T; Del Maestro, R; Knuechel, R; Dahl, E (2008). Frequent expression loss of Inter-alpha-trypsin inhibitor heavy chain (ITIH) genes in multiple human solid tumors: a systematic expression analysis. BMC Cancer, 8:25. Postprint available at: http://www.zora.uzh.ch University of Zurich Posted at the Zurich Open Repository and Archive, University of Zurich. Zurich Open Repository and Archive http://www.zora.uzh.ch Originally published at: BMC Cancer 2008, 8:25. Winterthurerstr. 190 CH-8057 Zurich http://www.zora.uzh.ch Year: 2008 Frequent expression loss of Inter-alpha-trypsin inhibitor heavy chain (ITIH) genes in multiple human solid tumors: a systematic expression analysis Hamm, A; Veeck, J; Bektas, N; Wild, P J; Hartmann, A; Heindrichs, U; Kristiansen, G; Werbowetski-Ogilvie, T; Del Maestro, R; Knuechel, R; Dahl, E Hamm, A; Veeck, J; Bektas, N; Wild, P J; Hartmann, A; Heindrichs, U; Kristiansen, G; Werbowetski-Ogilvie, T; Del Maestro, R; Knuechel, R; Dahl, E (2008). Frequent expression loss of Inter-alpha-trypsin inhibitor heavy chain (ITIH) genes in multiple human solid tumors: a systematic expression analysis. BMC Cancer, 8:25. Postprint available at: http://www.zora.uzh.ch Posted at the Zurich Open Repository and Archive, University of Zurich. http://www.zora.uzh.ch Originally published at: BMC Cancer 2008, 8:25. Frequent expression loss of Inter-alpha-trypsin inhibitor heavy chain (ITIH) genes in multiple human solid tumors: a systematic expression analysis Abstract BACKGROUND: The inter-alpha-trypsin inhibitors (ITI) are a family of plasma protease inhibitors, assembled from a light chain - bikunin, encoded by AMBP - and five homologous heavy chains (encoded by ITIH1, ITIH2, ITIH3, ITIH4, and ITIH5), contributing to extracellular matrix stability by covalent linkage to hyaluronan.
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