SPHERA technology for life PRO

HYDROCEPHALUS PROGRAMMABLE SECURITY AGAINST Reservoir with base DEPROGRAMMING protection for punctioning With a unique design, the valve rotor has two mechanical safety locks that moves in opposite directions, and may have double or single locking against non-intentional deprogramming. Each lock is located on a magnet and is pushed against a SPHERA PRO pressure position by the PROGRAMMABLE SHUNT action of a spring.

Sphera Pro is a cerebral shunt system for intraventricular pressure control with a programmable valve. This product has been developed to provide ACCURACY on pressure control, SECURITY against deprogramming and EASY ADJUSTMENT procedure. When the magnetic fields from the environment, or an The valve has 08 different pressure settings, and pressure adjustment can be performed whenever necessary unilateral one (generated by MRI), by a non-invasive device and painless to patients. are able to move one of the Safety against magnetic fields deprogramming is provided by an exclusive double locking system, which holds the valve magnets and release one of at the chosen pressure even when the patient undergoes MR examinations of up to 3 teslas. the latches, the other is forced by the same fields to remain in the The Sphera Pro system can be supplied along with the Sphera Grav antigravity device which acts in intraventricular locking position, avoiding pressure control when the patient changes from the horizontal to the vertical position, preventing overdrainage especially Adjustment deprogramming for patients with Normal Pressure Hydrocephalus (NPH). mechanism of the valve. The valve and reservoir are made of polysulfone with a silicone coating and titanium connectors. The system’s ventricular and peritoneal catheter are made of transparent silicone with a radiopaque fillet which enables the visualization in imaging tests and minimizes the occurrence of calcification in its path. 8 Pressure of 21 cmH2O

7 Pressure of 19 cmH2O ACCURACY WITH THE ADJUSTMENT MECHANISM 6 Pressure of 16,5 cmH2O 5 Pressure of 13 cmH2O During the adjustment, the rotor movement changes the distance between the rotor axis and the Sphera mechanism (spring, sphera and conical ruby seat), 4 Pressure of 10 cmH2O increasing or decreasing the valve pressure. 3 Pressure of 6,5 cmH2O The precise rotor radius dimensional control allows the accurate definition of the 08 different levels of opening and closing pressures, providing a real 2 Pressure of 3 cmH2O control when the pressure adjustment is performed. 1 Pressure of 1 cmH2O Rotor unlocked by the Rotor locked even with Rotor double locked by 08 dierent programming device one lock unlocked by the the action of the springs pressure settings action of the magnetic elds

Antigravity mechanism

X-ray image of Sphera Pro for the 08 pressure settings, showing the inlet and outlet connectors, technology for life both magnets, the direction arrow, and the indicative mark for the valve laterality. EASY PRESSURE ADJUSTMENT ANTIGRAVITY DEVICE The programming device allows an Hiperdrainage control easy pressure adjustment as it provides easy valve location, Programmer painless to the patient and Compass immediate confirmation of the adjusted pressure, eliminating the necessity of image exams. Since the correct programming device centralization upon the valve Positioner is essential to the unlocking and 10 + 20 = 30

pressure adjustment, the reader has cmH2O an indication aligment system that confirms the right position. Sphera Pro Active Sphera Grav-20 functioning 10 + 14 = 24 on the postural change with cmH2O the Sphera Pro adjusted in 10 cmH O STEP 01 2 With the compass placed on the positioner, locate the valve. Sphera Grav

Align the positioner flow indication Active Out centered pointer: arrow with the peritoneal catheter path. programming device on the incorrect position By moving the positioner around the valve, align the center of the pointer 10 + 0 = 10 with the center of the compass. 0º cmH2O 45º While moving the compass, in both 90º directions, the pointer must remain still. Perform the reading.

Centered pointer: programming device on the correct position Sphera Pro Sphera Grav Active Inactive

The antigravity device Sphera Grav provides overdrainage control by performing automatic compensation for the system’s opening pressure as the patient postural changes. When the patient is in the supine position, no resistance will be built by Sphera Grav, only the Sphera Pro valve will be active. However, when the patient is in the orthostatic position, the maximum resistance of Sphera Grav will act along with the Sphera Pro adjustment pressure, making the shunt system more physiological and maintaining the intraventricular pressure more constant and with less risks of overdrainage.

STEP 02 STEP 03 Sphera Grav has 06 resistance options (10, 15, 20, 25, 30 or 35 cmH2O) to meet the different needs of pressure control for each patient. The device consists of tungsten and ruby spheres, polysulphone body, titanium connectors and silicone coating. Keep the positioner on the same site and insert the programmer Replace the programmer for the compass. Perform on the place of the compass. Turn counterclockwise to increase the the reading of the new pressure, keeping the pointer pressure and clockwise to decrease the pressure. center aligned with the center of the compass. Technical information on this product is not limited to the features presented in this catalog. For more information, request the For complete instructions on programming procedures please refer to the Instruction of Use. . Instructions for Use at [email protected] SPHERA PRO + SPHERA GRAV SPHERA GRAV SPHERA PRO PRO10223 PRO10215 Code SPHERAGRAV-35 SPHERAGRAV-30 SPHERAGRAV-25 SPHERAGRAV-20 SPHERAGRAV-15 SPHERAGRAV-10 Code UPRO10223-G35 UPRO10223-G30 UPRO10223-G25 UPRO10223-G20 UPRO10223-G15 UPRO10223-G10 UPRO10215-G35 UPRO10215-G30 UPRO10215-G25 UPRO10215-G20 UPRO10215-G15 UPRO10215-G10 Code catheters separated Valve and technology forlife UPRO10223 UPRO10215 pre-attached to thevalvepre-attached UNISHUNT -Peritoneal catheter 01 Cerebral ventricular straight catheter andangular of23,5cmwithstainlesssteel stylet 01 Sphera Grav-35 device; 01Peritonial catheter of102cm;01RHH-2reservoir; 01 Hydrocephalus valve Sphera Pro to: pre-attached 01 Cerebral ventricular straight catheter andangular of23,5cmwithstainlesssteel stylet 01 Sphera Grav-30 device; 01Peritonial catheter of102cm;01RHH-2reservoir; 01 Hydrocephalus valve Sphera Pro to: pre-attached 01 Cerebral ventricular straight catheter andangular of23,5cmwithstainlesssteel stylet 01 Sphera Grav-25 device; 01Peritonial catheter of102cm;01RHH-2reservoir; 01 Hydrocephalus valve Sphera Pro to: pre-attached 01 Cerebral ventricular straight catheter andangular of23,5cmwithstainlesssteel stylet 01 Sphera Grav-20 device; 01Peritonial catheter of102cm;01RHH-2reservoir; 01 Hydrocephalus valve Sphera Pro to: pre-attached 01 Cerebral ventricular straight catheter andangular of23,5cmwithstainlesssteel stylet 01 Sphera Grav-15 device; 01Peritonial catheter of102cm;01RHH-2reservoir; 01 Hydrocephalus valve Sphera Pro to: pre-attached 01 Cerebral ventricular straight catheter andangular. of23,5cmwithstainlesssteel stylet 01 Sphera Grav-10 device; 01Peritonial catheter of102cm;01RHH-2reservoir; 01 Hydrocephalus valve Sphera Pro to: pre-attached 01 Cerebral ventricular straight catheter andangular of15cmwithstainlesssteel stylet 01 Sphera Grav-35 device; 01Peritonial catheter of102cm;01RHH-2reservoir; 01 Hydrocephalus valve Sphera Pro to: pre-attached 01 Cerebral ventricular straight catheter andangular. of15cmwithstainlesssteel stylet 01 Sphera Grav-30 device; 01Peritonial catheter of102cm;01RHH-2reservoir; 01 Hydrocephalus valve Sphera Pro to: pre-attached 01 Cerebral ventricular straight catheter andangular. of15cmwithstainlesssteel stylet 01 Sphera Grav-25 device; 01Peritonial catheter of102cm;01RHH-2reservoir; 01 Hydrocephalus valve Sphera Pro to: pre-attached 01 Cerebral ventricular straight catheter andangular. of15cmwithstainlesssteel stylet 01 Sphera Grav-20 device; 01Peritonial catheter of102cm;01RHH-2reservoir; 01 Hydrocephalus valve Sphera Pro to: pre-attached 01 Cerebral ventricular straight catheter andangular. of15cmwithstainlesssteel stylet 01 Sphera Grav-15 device; 01Peritonial catheter of102cm;01RHH-2reservoir; 01 Hydrocephalus valve Sphera Pro to: pre-attached 01 Cerebral ventricular straight catheter andangular. of15cmwithstainlesssteel stylet 01 Sphera Grav-10 device; 01Peritonial catheter of102cm;01RHH-2reservoir; 01 Hydrocephalus valve Sphera Pro to: pre-attached Content 01 Antigravity device withequivalent resistance to pressure of10cmH 01 Antigravity device withequivalent resistance to pressure of35cmH 01 Antigravity device withequivalent resistance to pressure of30cmH 01 Antigravity device withequivalent resistance to pressure of25cmH 01 Antigravity device withequivalent resistance to pressure of20cmH 01 Antigravity device withequivalent resistance to pressure of15cmH Content e-mail: [email protected] •www.hpbio.com.br São P Rua M HP BIOP aulo •SPBrasilCEP: ar ia JoséR R 01 Peritoneal catheter of102cm 01 Cerebral ventricular straight catheter andangular of23,5cmwithstainlesssteel stylet 01 Hydrocephalus valve Sphera Pro 01 Peritoneal catheter of102cm 01 Cerebral ventricular straight catheter andangular of15cmwithstainlesssteel stylet 01 Hydrocephalus valve Sphera Pro Content OTES E S angel, L TDA 83•VilaSãoP 04650-180•T aulo el.: 2 2 2 2 2 2 O O O O O O 551138537625 . . . . .