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“The Matrix in Focus” Meeting Chair: Jeffrey Miner, Washington University in St American Society for Matrix Biology Biennial Meeting 2020 ASMB Biennial Meeting ◆ November 8-11, 2020 Hyatt Regency St. Louis Arch St. Louis, MO “The Matrix in Focus” Meeting Chair: Jeffrey Miner, Washington University in St. Louis Sunday, November 8th Plus 4 selected talks from abstracts Concurrent 3: Basement Membranes and 9:00am - 6:00pm Registration Disease Location: Grand Foyer Therapeutic Implications of Mechanistic 10:30am - 12:00pm Guest Symposia I & II Heterogeneity in Patients with COL4A1 and Location: Grand ABC, Grand D COL4A2 Mutations, Douglas Gould, University of California, San Francisco 10:30am - 12:00pm Poster Flash Talks Location: Grand E Plus 4 selected talks from abstracts Highly recognized abstracts that were not selected for a concurrent session will be presented in this 2:30-2:45pm Break fast-paced forum. Location: Grand Foyer 12:00-6:00pm Exhibits 2:45-4:15pm Concurrent Sessions Location: Grand Foyer Special Interest Session 1 - TBA 12:00-1:00pm Break – Lunch on Your Own Concurrent 4: Elastic Fibers 12:00-1:00pm Networking Brown Bag Bring your own lunch and join an informal Elastic Fibers and Arterial Mechanics, Jessica discussion group! Wagenseil, Washington University in St. Louis 1:00-2:30pm Concurrent Sessions Plus 4 selected talks from abstracts Concurrent 1: Fibroblasts & ECM Remodeling Concurrent 5: Mechanisms of Fibrosis Cardiac Fibroblasts: Purveyors of Ventricular Cellular and Molecular Regulation of Matrix Stiffness, Amy Bradshaw, Medical University of Protein Production, Valerie Horsley, Yale South Carolina University Plus 4 selected talks from abstracts Plus 4 selected talks from abstracts Concurrent 2: Game of Bones: ECM & Skeletal Biology 4:15-4:30pm Break Location: Grand Foyer Global Knockout Mouse Models Reveal Cooperative Effects of Thrombospondins 1 4:30-6:00pm President’s Welcome & and 2 on Bone Cell Physiology, Andrea Alford, Award Talks University of Michigan Location: Grand D-F American Society for Matrix Biology Biennial Meeting 2020 Junior Investigator Awardee, Iozzo Award Winner, Senior Investigator Awardee Human Kidney Organoids for Unravelling the Drivers of Early Kidney Development 6:00-7:00pm Welcome Reception and Disease, Sue Kimber, University of Location: Grand Foyer Manchester 7:00-7:15pm Founders Award Talk Multiple Roles of Tenascin-C in Cancer Location: Grand D-F Progression, Gertraud Orend, INSERM, Strasbourg 7:15-8:00pm Keynote Lecture Tumor ECM Remodeling to Facilitate Location: Grand D-F Metastasis, Greg Longmore, Washington Creating a State Space of Human Stem Cell University in St. Louis Signatures, Rick Horwitz, Allen Institute for Cell Science 12:00-12:30pm ASMB Business Meeting th Monday, November 9 12:30-2:30pm Poster Session I Location: Grand FGH and Park View 7:15-8:30am Career Mentoring Breakfast Odd Number Boards Present Discussion begins at 7:30am Location: Mills Room TBD 2:30-4:00pm Concurrent Sessions 7:30am-5:30pm Registration and Exhibits Concurrent 6: Matricellular Proteins Location: Grand Foyer At the Nexus of Contraction and Matrix 7:30-8:30am Breakfast Synthesis: Periostin as a Modulator of Soft Location: Grand Foyer Tissue Repair, Douglas Hamilton, University of Western Ontario 8:30-10:00am Plenary I: Stem Cells, Organogenesis, and Regeneration Plus 4 selected talks from abstracts Skeletal Stem Cells in the Growth Plate: Concurrent 7: Genetics of Connective Tissue Deeply Embedded in the Niche, Noriaki Disorders Ono, University of Michigan Genetic Variants, Aortic Dissection, and Talk Title TBA, Natasza Kurpios, Cornell Receptor-Matrx Interactions, Dianna M. University (invited) Milewicz, The University of Texas Health Science Center at Houston, McGovern Medical Injectable ECM Hydrogels for School Regenerative Engineering, Karen L. Christman, University of California, San Plus 4 selected talks from abstracts Diego Concurrent 8: Mechanobiology 10:00-10:30am Coffee Break Location: Grand Foyer Biochemical and Biophysical Regulation of Integrin-mediated Adhesion Initiation to 10:30-12:00pm Plenary II: Let’s Not Forget Fibronectin, Nico Strohmeyer, ETH Zurich the Microenvironment American Society for Matrix Biology Biennial Meeting 2020 Plus 4 selected talks from abstracts Syndecan Interactions in Innate Immunity and Gram+ Infections, Pyong Woo Park, Boston Children’s Hospital and Harvard 4:00-4:30pm Coffee Break Medical School Location: Grand Foyer Cell-mediated Collagen Degradation in Homeostasis and Disease, Kamran Atabai, 4:30-6:00pm Concurrent Sessions University of California, San Francisco Concurrent 9: Therapeutic Targeting of Matrix 9:30-10:15am ISMB Distinguished Investigator Award Presentation Talk Title TBA, Jacqueline Hecht, The Location: Grand D-F University of Texas Health Science Center at Houston, McGovern Medical School 10:15-10:30am Coffee Break Location: Grand Foyer Plus 4 selected talks from abstracts 10:30-12:00pm Plenary IV: Little Guys, Big Concurrent 10: Cardiovascular Biology & ECM Questions Remodeling Location: Grand D-F Role of Disintegrin and Metalloproteinases Basement Membrane Dynamics in (ADAMs) in Fibroblast Function and Homeostasis and Repair, Andrea Page- Fibrosis in Heart Disease, Zamaneh Kassiri, McCaw, Vanderbilt University University of Alberta A Basement Membrane Toolkit in the Plus 4 selected talks from abstracts Worm: Formation, Growth, and Moving Matrix Components Revealed, David Sherwood, Duke University Guest Society or SIS TBA Lizard Tail Regeneration As an Instructive Model of Enhanced Healing Capabilities in th Tuesday, November 10 an Adult Amniote, Thomas Lozito, University of Southern California Keck School of 7:15-8:30am Women Mentoring Women Medicine Breakfast Discussion begins at 7:30am Location: Mills Room TBD 12:00-2:00pm Poster Session II 7:30am-5:30pm Registration and Exhibits Location: Grand FGH and Park View Location: Grand Foyer Even Number Boards Present 7:30-8:30am Breakfast 2:00-3:30pm Concurrent Sessions Location: Grand Foyer Concurrent 11: ECM Changes with Aging 8:30-9:30am Plenary III: Catching Pressure: Collagen and Glaucoma, Matrix, Infection, & Metabolism Ian Sigal, University of Pittsburgh School of Medicine Anne Woods Memorial: Joanne Murphy- Ullrich, ASMB Past-President Plus 4 selected talks from abstracts American Society for Matrix Biology Biennial Meeting 2020 Concurrent 12: Structural Aspects of ECM, Receptors, & Adhesion 8:00am-11:00am Exhibits Location: Grand Foyer Structural Mechanism of Laminin Recognition by Integrins, Junichi Takagi, 7:30-8:30am Breakfast Osaka University Location: Grand Foyer Plus 4 selected talks from abstracts 8:30-9:30am Iozzo Award Presentations Guest or Special Interest Session 9:45-11:15am Plenary V: TBD Mechanotransduction: Biology Meets 3:30-4:00pm Coffee Break Engineering Location: Grand Foyer Three-dimensional Tunable Collagen- 4:00-5:30pm Concurrent Sessions fibronectin Scaffolds for Cancer Research, Delphine Gourdon, University of Ottawa Concurrent 13: Proteoglycans & Glycobiology Myofibroblast Matrix – Memory, Mechanics, Cell Surface Hyaluronan Degradation and and Mechanisms, Boris Hinz, University of Cell Behavior, Yu Yamaguchi, Scripps Institute Toronto Plus 4 selected talks from abstracts Matrix Mechanics in Cancer Progression, Cynthia Reinhart-King, Vanderbilt University Concurrent 14: Home is Where the Matrix is: Stem Cell Niches 11:15-11:30am Coffee Break Location: Grand Foyer Controlling the Cytoskeleton to Build a Better Pancreas, Jeffrey Millman, Washington 11:30am -1:00pm Concurrent Sessions University in St. Louis Concurrent 16: Collagens & Friends Plus 4 selected talks from abstracts Quantifying 3D Collagen-fiber Organization, Concurrent 15: Cell Migration through ECM Kimani Toussaint, Brown University Live Imaging of the Inflammatory Response Plus 4 selected talks from abstracts and Its Consequences in Wound Repair and Cancer, Paul Martin, University of Bristol Concurrent 17: Matrix Proteases: Chop ‘til They Drop Plus 4 selected talks from abstracts Membrane-Anchored Matrix 7:00-11:00pm Social Event – City Museum, Metalloproteinases & the Pathophysiologic 750 North 16th Street Remodeling of the Extracellular Matrix, (All are invited!) Stephen Weiss, University of Michigan Plus 4 selected talks from abstracts Wednesday, November 11th Special Interest Session 3 8:00am-12:00pm Registration TBA Location: Grand Foyer .
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