Supplementary Appendix
Supplementary Appendix This appendix has been provided by the authors to give readers additional information about their work. Supplement to: Mann JFE, Ørsted DD, Brown-Frandsen K, et al. Liraglutide and renal outcomes in type 2 diabetes. N Engl J Med 2017;377:839-48. DOI: 10.1056/NEJMoa1616011 Supplementary Appendix Liraglutide and Renal Outcomes in Type 2 Diabetes Johannes F.E. Mann, M.D.,1,2 David D. Ørsted, M.D., Ph.D.,3 Kirstine Brown-Frandsen, M.D.,3 Steven P. Marso, M.D.,4 Neil R. Poulter, F.Med.Sci.,5 Søren Rasmussen, Ph.D,3 Karen Tornøe, M.D., Ph.D.,3 Bernard Zinman, M.D.,6 John B. Buse M.D., Ph.D.,7 on behalf of the LEADER Steering Committee and Investigators 1Friedrich Alexander University of Erlangen, Erlangen, Germany; 2KfH Kidney Center, Munich, Germany; 3Novo Nordisk, Bagsvaerd, Denmark; 4University of Texas Southwestern Medical Center, Dallas, TX, USA; 5Imperial College London, London, UK; 6Lunenfeld– Tanenbaum Research Institute, Mt. Sinai Hospital, University of Toronto, Toronto, Canada; 7University of North Carolina School of Medicine, Chapel Hill, NC, USA Supplementary Methods Page 2 Supplementary Figures and Tables Page 5 Figure S1a. Urinary albumin-to-creatinine: ratio to baseline at 3-year visit in subgroups stratified according to albuminuria at baseline Page 5 Figure S1b. Urinary albumin-to-creatinine during trial in subgroups stratified according to albuminuria at baseline Page 6 Figure S2. Estimated GFR: ratio to baseline at 3-year visit in subgroups stratified according to eGFR at baseline Page 7 Table S1. Microvascular, renal and eye events Page 8 Table S2.
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