IVF Histories and Cultures Workshop 3 22-23Rd June 2015, Christ's
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Fertility Network UK Magazine – Autumn 2016
INUK Autumn 2016.e$S_Layout 1 11/10/2016 10:21 Page 1 No.51 Autumn 2016 The national charity, here for anyone who has ever experienced fertility problems NHS Funding Fundin g for NHS fertility treatmen the country, with access entir your postcode. t var ely dependies across ent on Information aby, you can find If you are trying to have a b rmation about fertility problems, treatment info upport here. options, funding and emotional s News News art parents icles f or those trying to become Support Our support network is here to offer those affected by fertility issues the support and understanding they need, when they need it. Events We have details of events which are free to attend and we will also list details of open days and free patient events for clinics who are members of our clinic outreach scheme. Our new website will be launched at The Fertility Show in November: www.fertilitynetworkuk.org INUK Autumn 2016.e$S_Layout 1 11/10/2016 10:23 Page 2 Fertility Network UK Susan Seenan Staff Gallery Chief Executive [email protected] Tel: 01294 230730 Mobile: 07762 137786 Sheena Andrew Coutts Catherine Hill Gillian Young Business Media McLaughlin Head of Development Relations Volunteer Business Manager Officer Co-ordinator Development [email protected] [email protected] [email protected] [email protected] Mobile: 07710 764162 Mobile: 07794 372351 Mobile: 07469 660845 Mobile: 07909 686874 Head Office Claire Heritage Alison Hannah Head Office Onash Tramaseur Manager Administrator -
3 Franklin TS 4-1(M)
Lecture Embryo Watching How IVF Has Remade Biology Sarah Franklin University of Cambridge Abstract In addition to being one of the most iconic of the new reproduc- tive technologies introduced in the late twentieth century, in vitro fertiliza- tion is also a technology of representation – a looking glass into conception, a window onto early human development, and as such a new form of public spectacle. Still a rapidly expanding global biomedical service sector, IVF tech- nology is also the source of new images of human origins, and thus offers a new visual grammar of coming into being. This lecture explores these con- nections, and argues that the micromanipulation imagery associated with IVF, and now a routine feature of news coverage and popular debate of NRTs, al- so introduces a new connection between cells and tools, thus returning us to one of the oldest sociological questions – the question concerning technolo- gy. Moving between IVF as a technology of reproduction, and a visual tech- nology, enables us to revisit a series of broad sociological questions concern- ing technology, reproduction, genealogy and the future of biological control from the unique perspective offered by the conversion of the human embryo into both a tool and a lens. Keywords IVF; micromanipulation; human embryo; biological control; visual culture. Corresponding author Sarah Franklin, Department of Sociology, Free School Lane, Cambridge CB2 3RQ, United Kingdom - Email: [email protected] 1. Introduction Although its first human offspring were not born until the1970s, in vitro fertilization is now at least a century old, and is itself the product of many generations of accumulated scientific expertise. -
Full Programme
Ways of Working online symposium programme 2.00pm-2.05pm Welcome from Allen Packwood, Director of Churchill Archives Centre. 2.05pm-2.35pm Madelin Evans (Edwards Papers Archivist, Churchill Archives Centre) and Professor Nick Hopwood (Department of History and Philosophy of Science, University of Cambridge) in conversation about using the archive of Robert Edwards for research. 2.35pm-3.05pm Professor Sarah Franklin (Reproductive Sociology Research Group, University of Cambridge) and Gina Glover (Artist, creator of Art in ART: Symbolic Reproduction exhibition) on working with images of reproduction in the Edwards archive. 3.05pm-3.15pm Break, with the chance to view a film of Art in ART: Symbolic Reproduction exhibition by Gina Glover 3.15pm-3.45pm Dr Kay Elder (Senior Research Scientist, Bourn Hall Clinic) and Dr Staffan Müller-Wille (University Lecturer, Department of History and Philosophy of Science, University of Cambridge) on using clinical research notebooks, and scientific notebooks and manuscripts, for historical research. 3.45pm-4.15pm Professor Sir Richard Gardner (Emeritus Royal Society Research Professor in the University of Oxford) and Professor Roger Gosden (lately Professor at Cornell University, now Visiting Scholar at William & Mary and official biographer of Robert Edwards) on Robert Edwards’ style of working in the laboratory. 4.15pm-4.30pm Dr Jenny Joy (daughter of Robert Edwards, key in gathering together his archive) will talk about her experience of how her father worked. 4.30pm-5pm Concluding remarks, questions and discussion The Papers of Professor Sir Robert Edwards, at Churchill Archives Centre The archive comprises 141 boxes of personal and scientific papers including correspondence, research and laboratory notebooks, draft publications and journal articles, newspaper clippings, photographs, videos and film. -
Multicentre Study of the Clinical Relevance of Screening IVF Patients for Carrier Status of the Annexin A5 M2 Haplotype
RBMO 1128 No. of Pages 8, Model 6+ 15 April 2014 Reproductive BioMedicine Online (2014) xxx, xxx– xxx www.sciencedirect.com www.rbmonline.com ARTICLE 7 4 Multicentre study of the clinical relevance 8 5 of screening IVF patients for carrier status 6 of the annexin A5 M2 haplotype a, b b c 9 Simon Fishel *, Rashmi Patel , Alison Lytollis , Jeanette Robinson , e d a a 10 Mary Smedley , Paula Smith , Craig Cameron , Simon Thornton , a b d e 11 Ken Dowell , Glenn Atkinson , Adel Shaker , Philip Lowe , c f f 12 Rahnuma Kazem , Sandra Brett , Anna Fox 13 a CARE Fertility Group, John Webster House, 6 Lawrence Drive, Nottingham Business Park, Nottingham NG8 6PZ, United 14Q1 Kingdom; b CARE Manchester, 108–112 Daisy Bank Road, Victoria Park, Manchester M14 5QH, United Kingdom; c CARE 15 Northampton, 67 The Avenue, Cliftonville, Northampton NN1 5BT, United Kingdom; d CARE Sheffield, 24–26 Glen Road, 16 Sheffield S7 1RA, United Kingdom; e CARE Nottingham, John Webster House, 6 Lawrence Drive, Nottingham Business Park, 17 Nottingham NG8 6PZ, United Kingdom; f CARE Dublin, Beacon CARE Fertility, Beacon Court, Sandyford, Dublin 18, Ireland 18 * Corresponding author. E-mail address: simon.fi[email protected] (S Fishel). Simon Fishel is CEO of CARE Fertility Group. He commenced research at Cambridge University with Bob Edwards in 1975. In 1980, he joined Patrick Steptoe and Bob at the start of Bourn Hall and was also awarded the prestigious Beit Memorial Fellowship and Research Fellowship at Churchill College. He has published more than 200 papers and three books and has received many international awards. -
Introduction: IVF—Global Histories
Reproductive BioMedicine and Society Online (2016) 2,1–7 www.sciencedirect.com www.rbmsociety.com SYMPOSIUM: IVF — GLOBAL HISTORIES Introduction Sarah Franklin a,⁎, Marcia C. Inhorn b a Reproductive Sociology Research Group (ReproSoc), University of Cambridge, UK; b Department of Anthropology, Yale University, US * Corresponding author. E-mail address: [email protected] (S. Franklin). Professor Sarah Franklin is a Wellcome Trust Senior Investigator and Director of the Reproductive Sociology Research Group at the University of Cambridge where she holds the Chair of Sociology. She is the author of more than 150 articles, chapters and books on the social aspects of reproductive biomedicine. Marcia C. Inhorn is the William K. Lanman, Jr. Professor of Anthropology and International Affairs at Yale University. A specialist on Middle Eastern gender, religion, and reproductive health, Inhorn has conducted research on the social impact of infertility and assisted reproductive technologies in Egypt, Lebanon, the United Arab Emirates, and Arab America over the past 30 years. She is the author of five books on the subject and is currently conducting a National Science Foundation-funded research project on oocyte cryopreservation for both medical and elective fertility preservation. Abstract The contributions to this Symposium issue of RBMS have been prepared following a unique meeting held at Yale University in April 2015 entitled IVF: Global Histories. The articles gathered here present empirical histories of the development of IVF in various countries. These are not intended to be ethnographic, or to develop major new theoretical or conceptual arguments, but rather aim to be indicative case studies situating the development of IVF in specific national contexts with an emphasis on how particular societal influences in the various countries affected the development of the IVF industries there. -
Postmodern Procreation: a Cultural Account of Assisted Reproduction
EIGHTEEN Postmodern Procreation: A Cultural Account of Assisted Reproduction Sarah Franklin What is in crisis here is the symbolic order, the conceptualisation of the relationship between nature and culture such that one can talk about the one through the other Nature as a ground for meaning can no longer be taken for granted if Nature itself is regarded as having to be protected and promoted. -MARILYN STRATHERN, After Nature Popular conceptions of new reproductive technology often take as their starting point the birth of Louise Brown, the world's first "test-tube baby," born in Oldham, Lancashire, in July 1978. From an anthropological perspective, this conception story is an overdetermined one. With the birth of Louise Brown also came into being a new kind of public debate about conception, in which unprecedented procreative possibilities raised moral uncertainty and political controversy. Both the moral issues and the political implications remain controversial today. In the process of formulating legislation, for example, considerable concern continues to be expressed about how to establish a legitimate foundation for decision making and debate in the field of assisted reproduction. Feminists have shared these concerns and dilemmas and have struggled to come to terms with rapid advances in the field of reproductive technology. Reproduction has long been a significant focus of feminist theory and politics because of the way in which its control has been seen as instrumental to the subordination of women in a patriarchal culture. Early feminist critiques focused upon motherhood as a patriarchal institution (Rich 1976), the medicalization of pregnancy by the maledominated medical profession (Donnison 1977; Ehrenreich and English 1973a, 1973b, 1978), the history of birth control (Gordon 1977), and the patriarchal desire to control the reproductive process (Firestone 1970, O'Brien 1981). -
Time-Lapse Imaging Algorithms Rank Human Preimplantation Embryos According to the Probability of Live Birth
304 RBMO VOLUME 37 ISSUE 3 2018 ARTICLE Time-lapse imaging algorithms rank human preimplantation embryos according to the probability of live birth BIOGRAPHY Simon Fishel, Founder and President of CARE Fertility Group, Fellow of the Royal Society of Biology worked with IVF pioneer and Nobel Laureate Robert Edwards from 1975-1985 at Cambridge University and as Deputy Scientific Director of the first IVF clinic, Bourn Hall. In 1978 he received the Beit Memorial Fellowship and was elected Research Fellow of Churchill College, Cambridge. In 2009 was awarded Liverpool John Moores University Honorary Fellowship for ”outstanding contributions to humanity and science in the field of fertility treatment including embryology and IVF” Simon Fishel1, Alison Campbell1,*, Sue Montgomery2, Rachel Smith3, Lynne Nice4, Samantha Duffy2, Lucy Jenner5, Kathryn Berrisford5, Louise Kellam5, Rob Smith6, Fiona Foad7, Ashley Beccles1 KEY MESSAGE This retrospective study demonstrated for the first time that human blastocyst embryos can be objectively ranked according to their propensity to produce a live birth using an in-house derived morphokinetic-based algorithm from time-lapse imaging. This appears to have greater discriminating power than subjective, conventional morphology assessment. ABSTRACT Research question: Can blastocysts leading to live births be ranked according to morphokinetic-based algorithms? Design: Retrospective analysis of 781 single blastocyst embryo transfers, including all patient clinical factors that might be potential confounders for the primary outcome measure of live birth, was weighed using separate multi-variable logistic regression models. Results: There was strong evidence of effect of embryo rank on odds of live birth. Embryos were classified A, B, C or D according to calculated variables; time to start (tSB) and duration (dB{tB – tSB}) of blastulation. -
Annual Conference RM
INTERNATIONAL CONFERENCE FINAL PROGRAMME 2017 Annual conference in reproductive medicine Recurrent implantation failure: A journey into deep understanding 21-22 April 2017 - Milan, Italy O F N I L A R E N E G GENERAL INFORMATION 2017 Annual conference in reproductive medicine Recurrent implantation failure: A journey into deep understanding Overview The ability to recognize the nature of failed implantation is extremely important to the success of ART. To this end, greater emphasis is being placed on understanding crucial biological processes involved in human embryo implantation. Researchers have endeavored to unravel the key aspects of implantation by studying the various endometrial, immunological, genomic and embryological facets of the process. A number of interventions are suggested for improving implantation and more importantly for overcoming the challenge of recurrent implantation failure (RIF). A firm grasp of basic science and an eye for evidence are central to implementing what will work for patients. This conference will critically appraise methods and techniques suggested for overcoming RIF and enhancing ART outcomes. Learning will be supported through lively discussion and debate as well as opportunities to meet experts for one-on-one discussion. Learning objectives By attending this live educational conference , participants will: • Acquire knowledge on the key biological aspects of human embryo implantation and causes of RIF • Enhance their understanding of advanced techniques to maximize implantation and treat RIF • Be able to apply evidence-based practices to achieve optimal outcomes from ART Target audience This conference is targeted at clinicians, embryologists and scientists working in ART who wish to update their knowledge of advanced techniques and scientific innovation. -
Cryostorage and Retransplantation of Ovarian Tissue As an Infertility Treatment
Best Practice & Research Clinical Endocrinology & Metabolism xxx (2018) 1e14 Contents lists available at ScienceDirect Best Practice & Research Clinical Endocrinology & Metabolism journal homepage: www.elsevier.com/locate/beem 9 Cryostorage and retransplantation of ovarian tissue as an infertility treatment * Christiani A. Amorim, DMV, PhD, Professor a, , Ellen Cristina Rivas Leonel, MSc a, b, Yousri Afifi, MD, PhD c, Arri Coomarasamy, MD, M.R.C.O.G., Professor d, e, Simon Fishel, PhD, FRSB, Professor f a Pole^ de Recherche en Gynecologie, Institut de Recherche Experimentale et Clinique, Universite Catholique de Louvain, Avenue Mounier 52, bte. B1.52.02, 1200, Brussels, Belgium b Department of Biology, Institute of Biosciences, Humanities and Exact Sciences, Sao~ Paulo State University, Rua Cristov ao~ Colombo, 2265 Jardim Nazareth, 15054-000, Sao~ Jose do Rio Preto, Sao~ Paulo, Brazil c Department of Obstetrics and Gynaecology, Birmingham Women's NHS Foundation Trust, Birmingham, United Kingdom d Tommy's National Centre for Miscarriage Research, Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, B15 2TT, United Kingdom e Birmingham Women's and Children's NHS Foundation Trust, Mindelsohn Way, Birmingham, B15 2TG, United Kingdom f CARE Fertility Group, John Webster House, 6 Lawrence Drive, Nottingham Business Park, Nottingham, NG8 6PZ, United Kingdom article info While still considered an experimental procedure in most coun- Article history: tries, ovarian tissue cryopreservation and transplantation has been Available online xxx increasingly applied worldwide to restore fertility in patients with malignant and non-malignant pathologies with risk of premature Keywords: ovarian insufficiency. It has yielded more than 130 live births up to cryopreservation now and almost all transplanted patients recovered their ovarian transplantation function. -
In Search of Oogonial Stem Cells
focus on REPRODUCTION In search of oogonial stem cells Best of ESHRE & ASRM 2017 // MAY 2017 Switzerland: 35 years of IVF All rights reserved. The opinions expressed in this magazine are those of the authors and/or persons interviewed and do not necessarily reflect the views of ESHRE. MAY 2017 EXECUTIVE COMMITTEE // Chairman Kersti Lundin (SE) // Chairman Elect Roy Farquharson (GB) // Members Basak Balaban (TR), Mariette Goddijn (NL), Georg Griesinger (DE), Grigoris Grimbizis (GR), Borut Kovacic (SI), Nicholas Macklon (GB), Tatjana Motrenko (ME), Andres Salumets (EE), Petra De Sutter (BE), Rita Vassena (ES) Ex-officio members // Juha Tapanainen (FI, Past Chairman), Helen Kendrew (GB, Paramedical Group), Cristina Magli (IT, SIG Committee) FOCUS ON REPRODUCTION EDITORIAL COMMITTEE // Susanna Apter, Christine Bauquis, Bruno Van den Eede, Hans Evers, Roy Farquharson, Kersti Lundin, Nick Macklon, Juha Tapanainen, Rita Vassena, Anna Veiga, Simon Brown (Editor) FOCUS ON REPRODUCTION is published by The European Society of Human Reproduction and Embryology, Meerstraat 60, Grimbergen, Belgium // www.eshre.eu COVER PICTURE: Josephine van der Klaauw CHAIRMAN’S INTRODUCTION As I will shortly complete my two-year term as Chairman of ESHRE, this will be my last editorial for Focus on Reproduction. At our Annual Meeting in Geneva I will become Past Chairman, and Roy Farquharson will take over. CONTENTS ESHRE’s chairmen’s cycle of serving two years as Chair Elect (to gain understanding of the Society’s structure, processes and tasks), two as READY FOR GENEVA 2017 4 Chairman, and two as Past Chair is a well functioning system which ensures continuity and ‘memory’ within the system - and a smooth turnover of GENERAL ASSEMBLY AGENDA 5 chairmen. -
Cryostorage and Retransplantation of Ovarian Tissue As an Infertility Treatment
Best Practice & Research Clinical Endocrinology & Metabolism 33 (2019) 89e102 Contents lists available at ScienceDirect Best Practice & Research Clinical Endocrinology & Metabolism journal homepage: www.elsevier.com/locate/beem 8 Cryostorage and retransplantation of ovarian tissue as an infertility treatment * Christiani A. Amorim, DMV, PhD, Professor a, , Ellen Cristina Rivas Leonel, MSc a, b, Yousri Afifi, MD, PhD c, Arri Coomarasamy, MD, M.R.C.O.G., Professor d, e, Simon Fishel, PhD, FRSB, Professor f a Pole^ de Recherche en Gynecologie, Institut de Recherche Experimentale et Clinique, Universite Catholique de Louvain, Avenue Mounier 52, bte. B1.52.02, 1200, Brussels, Belgium b Department of Biology, Institute of Biosciences, Humanities and Exact Sciences, Sao~ Paulo State University, Rua Cristov ao~ Colombo, 2265 Jardim Nazareth, 15054-000, Sao~ Jose do Rio Preto, Sao~ Paulo, Brazil c Department of Obstetrics and Gynaecology, Birmingham Women's NHS Foundation Trust, Birmingham, United Kingdom d Tommy's National Centre for Miscarriage Research, Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, B15 2TT, United Kingdom e Birmingham Women's and Children's NHS Foundation Trust, Mindelsohn Way, Birmingham, B15 2TG, United Kingdom f CARE Fertility Group, John Webster House, 6 Lawrence Drive, Nottingham Business Park, Nottingham, NG8 6PZ, United Kingdom article info While still considered an experimental procedure in most coun- Article history: tries, ovarian tissue cryopreservation and transplantation has been Available online 13 September 2018 increasingly applied worldwide to restore fertility in patients with malignant and non-malignant pathologies with risk of premature Keywords: ovarian insufficiency. It has yielded more than 130 live births up to cryopreservation now and almost all transplanted patients recovered their ovarian transplantation function. -
Sarah Franklin in Conversation with Silvia Posocco, Paul Boyce, and EJ Gonzalez-Polledo
Franklin, Sarah; Boyce, P; Gonzalez-Polledo, EJ and Posocco, S. 2019. Conceptuality in Relation: Sarah Franklin in Conversation with Silvia Posocco, Paul Boyce, and EJ Gonzalez-Polledo. In: Paul Boyce; EJ Gonzalez-Polledo and Silvia Posocco, eds. Queering Knowledge: Analytics, De- vices and Investments after Marilyn Strathern. London: Routledge. ISBN 9781138230989 [Book Section] https://research.gold.ac.uk/id/eprint/25091/ The version presented here may differ from the published, performed or presented work. Please go to the persistent GRO record above for more information. If you believe that any material held in the repository infringes copyright law, please contact the Repository Team at Goldsmiths, University of London via the following email address: [email protected]. The item will be removed from the repository while any claim is being investigated. For more information, please contact the GRO team: [email protected] Conceptuality in Relation: Sarah Franklin in conversation with Silvia Posocco, Paul Boyce, and EJ Gonzalez-Polledo Editors’ Note: In preparation for the interview, we worked together to develop a set of questions which we shared with Sarah Franklin in advance of our meeting. We met Sarah Franklin in Cambridge in March 2018. EJ: Would you like to contextualise for us when your relation with Marilyn Strathern’s work began? Sarah Franklin: I took a somewhat unusual path through academia because I did an undergraduate degree in women’s studies a long time ago I graduated in 1982, and there weren’t really any graduate programmes in feminism, gender or women’s studies in the early 1980s in the United States.