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Cardiac Assist Devices Cardiac Assist Devices Current and Pipeline Products GDME1006FPR / Published March 2013 Table of Contents 1 Table of Contents 1 Table of Contents ............................................................................................................... 2 1.1 List of Tables ............................................................................................................... 7 1.2 List of Figures ........................................................................................................... 13 2 Introduction ....................................................................................................................... 14 2.1 Catalyst ..................................................................................................................... 14 3 Competitive Assessment ................................................................................................... 16 3.1 Cardiac Assist Device Market, Comparison of Key Marketed Products ...................... 16 3.2 Ventricular Assist Devices Market, Key Company Share ............................................ 18 3.3 Ventricular Assist Devices, Comparison based on Pump Technology ........................ 19 3.4 Ventricular Assist Devices ......................................................................................... 20 3.4.1 Overview............................................................................................................. 20 3.4.2 First-Generation Devices ..................................................................................... 21 3.4.3 Second-Generation Devices ................................................................................ 22 3.4.4 Third-Generation Devices ................................................................................... 22 3.4.5 Fourth-Generation Devices ................................................................................. 23 3.4.6 Fifth-Generation Devices ..................................................................................... 23 3.4.7 Sixth-Generation Devices .................................................................................... 23 3.4.8 Seventh-Generation Devices ............................................................................... 23 3.4.9 Counterpulsation Devices ................................................................................... 23 3.4.10 Adult Primary Implant Breakdown........................................................................ 24 3.4.11 Brand-Specific Training ....................................................................................... 24 3.5 Extracorporeal Ventricular Assist Devices .................................................................. 25 3.5.1 AB5000 (Abiomed, Inc.) ...................................................................................... 25 3.5.2 CentriMag, PediMag (Thoratec) .......................................................................... 27 3.5.3 Delta-Stream DP3 Pump (Medos Medizintechnik AG) ......................................... 30 3.5.4 Excor (Berlin Heart)............................................................................................. 31 © GlobalData. This report is a licensed product and is not to be copied, reproduced, shared or resold in any form. Page 2 GDME1006FPR / Published MAR 2013 Table of Contents 3.5.5 PVAD (Thoratec) ................................................................................................. 33 3.5.6 RotaFlow (Maquet Cardiovascular) ..................................................................... 35 3.6 Intracorporeal Ventricular Assist Devices ................................................................... 37 3.6.1 DuraHeart (Terumo) ............................................................................................ 38 3.6.2 EvaHeart (Sun Medical Technology Research Corporation) ................................ 40 3.6.3 Heart Assist 5 (MicroMed Cardiovascular, Inc.) ................................................... 42 3.6.4 HeartMate II (Thoratec) ....................................................................................... 44 3.6.5 HVAD (HeartWare) ............................................................................................. 48 3.6.6 Incor (Berlin Heart) .............................................................................................. 52 3.6.7 IVAD (Thoratec) .................................................................................................. 54 3.6.8 Jarvik 2000 (Jarvik Heart) ................................................................................... 56 3.7 Percutaneous Ventricular Assist Devices ................................................................... 59 3.7.1 Impella (Abiomed, Inc.) ....................................................................................... 60 3.7.2 Synergy (CircuLite) ............................................................................................. 63 3.7.3 TandemHeart (Cardiac Assist, Inc.) ..................................................................... 66 3.8 Intra-Aortic Balloon Pumps ........................................................................................ 69 3.8.1 Overview............................................................................................................. 69 3.8.2 AutoCAT 2 Wave (Teleflex) ................................................................................. 71 3.8.3 CardioSave (Maquet Cardiovascular) .................................................................. 73 3.8.4 CS300 (Maquet Cardiovascular) ......................................................................... 75 3.8.5 iVAC (PulseCath) ................................................................................................ 77 3.8.6 Xemex (Zeon) ..................................................................................................... 78 3.9 Extra-Aortic Balloon Pumps ....................................................................................... 79 3.9.1 C-Pulse (Sunshine Heart) ................................................................................... 81 3.10 Total Artificial Heart ................................................................................................... 85 3.10.1 Overview............................................................................................................. 85 3.10.2 AbioCor (Abiomed).............................................................................................. 86 3.10.3 SynCardia (SynCardia Systems, Inc.).................................................................. 88 © GlobalData. This report is a licensed product and is not to be copied, reproduced, shared or resold in any form. Page 3 GDME1006FPR / Published MAR 2013 Table of Contents 3.11 Extracorporeal Membrane Oxygenation ..................................................................... 91 4 Pipeline Products .............................................................................................................. 92 4.1 Overview ................................................................................................................... 92 4.2 Ventricular Assist Devices ......................................................................................... 93 4.2.1 CorAide, DexAide (Teleflex) ................................................................................ 93 4.2.2 DuraHeart II (Terumo) ......................................................................................... 95 4.2.3 HeartMate III (Thoratec) ...................................................................................... 96 4.2.4 HeartMate X (Thoratec)....................................................................................... 97 4.2.5 MiFlow (HeartWare) ............................................................................................ 98 4.2.6 MiTiHeart LVAD (Mohawk Innovative Technology, Inc.)....................................... 99 4.2.7 MVAD (HeartWare) ........................................................................................... 101 4.2.8 PediaFlow VAD (HeartWare) ............................................................................. 103 4.2.9 PediPump (Cleveland Clinic) ............................................................................. 104 4.2.10 Revolution (Vadovations, Inc.) ........................................................................... 105 4.2.11 s.pump (Medos Medizintechnik AG) .................................................................. 106 4.3 Percutaneous Ventricular Assist Devices ................................................................. 107 4.3.1 HeartMate PHP (Thoratec) ................................................................................ 107 4.3.2 Reitan Catheter Pump (CardioBridge GmbH) .................................................... 108 4.4 Total Artificial Hearts ............................................................................................... 110 4.4.1 AbioCor II (Abiomed, Inc.) ................................................................................. 110 4.4.2 Carmat TAH (Carmat) ....................................................................................... 111 4.4.3 Golding TAH (Cleveland Clinic) ......................................................................... 113 4.4.4 Beatless Heart (Texas Heart Institute) ..............................................................
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