The mission of the

Prostate Cancer Foundation is to find better treatments

and a cure for recurrent

prostate cancer.

2006 Progress Report 1 As the Prostate Cancer Foundation nears its 15th year of seeking better treatments and an eventual cure for prostate cancer, we pledge to you – trusted partners, directors, donors, friends, survivors and families – that we will not rest until we accomplish the goal of ending death and suffering from prostate cancer. We’re accelerating our timetable, harnessing every available resource and delivering needed funds to investigators on the brink of finding new discoveries to benefit men and their families. Since 1993, generous donors like you have provided the means for the PCF to fund more than 1,400 investigators. We’ve received nearly 6,000 applications for our Competitive Awards Program that were submitted from scientific investigators at leading medical institutions in 43 countries. These investigators are on the frontline of research, working in concert to streamline their research approach and share best practices. And each year we bring together the world’s finest prostate cancer experts to collaborate on ideas, educate each other and energize the research field during the PCF Scientific Retreat. All this activity is focused on the fact that one in six American men will be diagnosed with prostate cancer, the most-diagnosed non-skin cancer in the United States. In 2006 alone, more than 234,000 men received the unfortunate news. But there is cause for hope. When the PCF began in 1993, there were seven approved drugs for prostate cancer – today there are 13. Most importantly, even as the population of men at greatest risk has grown with the aging baby boom, there has been a 22% decrease in prostate cancer deaths. We want that number to be zero, and we can get there. But we can’t do it alone. Just as we’re starting to turn the tide against prostate cancer, government funding for prostate cancer research is projected to decrease by 9% in 2007. We need your help to assist us in bridging the gap of resources. We need you to alert Washington that we will not tolerate a funding shortfall. And the timing is crucial. If we don’t increase the needed resources to learn how to prevent the disease, we will witness an estimated 37% increase in prostate cancer diagnoses by 2015 based on population trends. At the PCF, we’re aggressively accelerating our timetable to prevent this from happening. In 2007, we’re confidently building on the solid foundation created by nearly five years of leadership under the PCF’s previous chief executive officer, Leslie D. Michelson. Thank you to our many generous friends and donors for their support throughout the years. We look forward to working with you to put the PCF out of business.

Michael Milken Jonathan W. Simons, MD Founder and Chairman Chief Executive Officer and President David H. Koch Chair

2006 Progress Report 3 About Prostate Cancer

The Prostate Cancer Foundation is dedicated to harnessing and leveraging every available resource to find better treatments and a cure for recurrent prostate cancer. Prostate Cancer Risk Factors Prostate cancer occurs when the cells of the prostate Although all the detailed mechanisms underlying – a small, innocuous-looking gland that sits just the genetic damage in the prostate gland that leads below a man’s bladder inside his pelvis – begin to to development of prostate cancer remain unknown, grow uncontrollably. It is the most common non- risk factors for prostate cancer are well understood skin cancer in the United States, striking one in six and include age, race and family history. men. In 2006 alone, more than 234,000 men were • As men age, their risk of developing prostate diagnosed with prostate cancer and more than cancer increases significantly. About 65% of all 27,000 men died from the disease. Over the past prostate cancers are diagnosed in men over the decade, nearly 400,000 American men have been age of 65. lost to this disease and nearly 2 million men are • Compared with Caucasian men, African living with it. American men are 60% more likely to develop prostate cancer, more likely to develop aggressive prostate cancer and twice as likely to die from the disease. • Men with a first-degree relative – a father, a brother or even a son – with prostate cancer are twice as likely to develop the disease. The risk is even higher if the family members were diagnosed before age 60.

Bladder

Prostate

Prostate Cancer Cells

4 Prostate Cancer Foundation 2006 Progress Report 5 Detection and Diagnosis The Team Approach to More than 95% of men who are diagnosed with Prostate Cancer Management and treated for early-stage disease remain disease- The complexity of treating prostate cancer has free after five years compared with only 35% of yielded three different groups of prostate cancer men who are diagnosed with late-stage disease. specialists. Urologists, radiation oncologists and The PSA (prostate-specific antigen) blood test and medical oncologists all play important roles in the the digital rectal exam (DRE) are used to detect the management of men with prostate cancer presence of prostate cancer when no symptoms are and each group brings its own area of expertise present. An elevated PSA or an abnormal DRE can to the treatment of men with this disease. signal the need for a biopsy to examine the prostate Yet these groups of physicians often work cells and determine if they are cancerous. independently, potentially missing some The American Cancer Society recommends that opportunities to work as a team to maximize both the PSA and DRE should be offered annually treatment options. beginning at age 50 or earlier if there is a family Over the past few years, the PCF has worked history of prostate cancer. tirelessly to bring these groups together and to create a systemized team approach to prostate cancer management throughout the country. With this approach, men with prostate cancer can better benefit from the expertise of each type Probability of Diagnosis by Age of specialist at every step of the way – learning about all available treatment options and choosing the treatment approach that’s right for them.

4 Prostate Cancer Foundation 2006 Progress Report 5 PLAYER NO. NO. 234 Investigators 1,400 - Total number of awardees since inception Since 1993, the Prostate Cancer Foundation has funded the work of more than 1,400 investigators – promoting innovative ideas in prostate cancer research and novel concepts in drug discovery and development.

International prostate cancer investigators who partner with the PCF.

Dr. Donald S. Coffey with recipients of the 2006 Donald S. Coffey Career Development Award and their mentors.

Clinical investigators in the PCF Therapy Consortium.

6 Prostate Cancer Foundation 2006 Progress Report 7 Accomplishments in Science

Major programs instituted and implemented by the Prostate Cancer Foundation in 2006 helped researchers, physicians and patients stay up-to-date on the most recent research findings – and allowed the PCF to continue focusing its efforts on strategies to move the field forward. Therapy Consortium Prostate Cancer Symposium Thirteen years ago, when the PCF was founded, In 2006, nearly 1,500 practicing physicians, few institutions were focusing their efforts on biopharmaceutical executives and government establishing centers of excellence for prostate policy makers attended the Prostate Cancer NO. 234 cancer research. With funding from the PCF, eight Symposium, a three-day meeting focusing on institutions across the country were able to establish issues to advance the standard of multidisciplinary rigorous prostate cancer research programs and care of men with prostate cancer. The program was become leaders in conducting prostate cancer co-sponsored by a partnership among the PCF, the clinical trials. American Society of Clinical Oncology, the American Since its inception, the PCF has collectively provided Society for Therapeutic Radiology and Oncology, and more than $23 million to the Therapy Consortium the Society of Urologic Oncology. institutions, which include Cedars-Sinai Medical Consistent with the PCF’s efforts to promote a Center; Dana-Farber Cancer Institute; MD Anderson team approach to prostate cancer management, Cancer Center; Memorial Sloan-Kettering Cancer many presenters at the conference emphasized that Center; The Johns Hopkins University; the University important advances in patient care for prostate cancer of California, San Francisco; the University of come from coordinated efforts of all members of the Michigan; and the University of Wisconsin. healthcare team. The value of the PCF’s investment was demonstrated as nearly all were selected by the Department of Defense Prostate Cancer Research Program to receive three-year Clinical Consortium Awards, beginning in 2005. These awards are designed to help the nation’s leading research programs collaborate on clinical trials and further speed the development of new drugs and treatments for prostate cancer.

For a list of Therapy Consortium clinical investigators, see page 34.

6 Prostate Cancer Foundation 2006 Progress Report 7 PLAYER NO. Global 43 - Total number of countries that submitted applications for funding since inception The global reach of the Prostate Cancer Foundation has sparked innovative prostate cancer research projects in dozens of countries and has led to an increased focus on the need for improved prostate cancer therapies around the world.

In 2006, the 63 physicians and scientists who Competitive Awards Program There is no shortage of innovative and creative ideas in represented the “best of the best” in prostate prostate cancer research, only a shortage of resources cancer research received funding through the to pursue them completely. Each year, the PCF’s Competitive Awards Program. Nearly $6.1 million Competitive Awards Program provides funding to was distributed, adding to the nearly $81 million investigators with unique and creative solutions to distributed since the program’s inception in 1993.

some of prostate cancer’s more difficult questions. For a complete list of institutions and investigators who have received funds from the Competitive Awards Program, see pages 30-33. This focus on emerging scientific research has enabled the PCF to attract new talent to the prostate Argentina, Australia, Austria, Belgium, Brazil, Bulgaria, Cameroon, Canada, Chile, China, Czech Republic, Denmark, Finland, France, cancer research arena, and has played an important Germany, Greece, Hungary, India, Ireland, Israel, Italy, Japan, role in sparking novel ideas in drug discovery Kazakhstan, Kenya, Kuwait, Mexico, Netherlands, New Zealand, Nigeria, Norway, Portugal, Puerto Rico, Russia, Scotland, South and development. Africa, Spain, Sweden, Switzerland, Taiwan, Thailand, Turkey, United Kingdom, United States

Countries that submitted applications for funding since the Prostate Cancer Foundationʼs inception

8 Prostate Cancer Foundation 2006 Progress Report 9 Scientific Retreat Aspen Summit Each year, the PCF Scientific Retreat brings together Capitalizing on its strong relationships with a wide scientific leaders from universities, governmental range of individuals dedicated to fighting prostate agencies and the biopharmaceutical industry to cancer, the PCF brought together members of its discuss challenges and solutions to the prostate Board of Directors, key prostate cancer investigators, cancer problem. donors and friends to explore how the PCF can bring The 13th Annual Scientific Retreat in 2006 focused about new and significant advances in prostate the attention of more than 200 investigators from cancer research. five different countries on several major scientific The Aspen Summit offered participants a new areas of dramatic progress in the field and also some appreciation for the challenges in prostate cancer of the systemic obstacles that continue to impede research today and highlighted the profound role success in prostate cancer research. that the PCF can play in accelerating progress toward finding better treatments and a cure for Sessions held during the Retreat highlighted recurrent prostate cancer. critical areas of research currently underway at leading institutions around the world. Investigators presented landmark work in identifying molecular changes that play a key role in the development of prostate cancer and reviewed in detail laboratory studies being conducted on molecular targets and pathways known to play a role in prostate cancer progression. Most important, the discussions during all of the sessions revolved around how all of these findings might lead to the development of better treatments and a cure for prostate cancer.

Career Development Awards Over the years, funding from the PCF has been an essential source of support for young physician- scientists who are starting their careers in prostate cancer research. In 2006, four outstanding junior PCF-funded investigators Dr. Isla P. Garraway and her faculty members at National Cancer Institute- brother Dr. Levi A. Garraway. designated Comprehensive Cancer Centers received Career Development Awards and were invited to present their work at the PCF Scientific Retreat. The Career Development Program is named for Dr. Donald S. Coffey of The Johns Hopkins University, who is often referred to as one of the founding “fathers” of prostate cancer research. Dr. Coffey’s renowned emphasis on mentorship has set a standard for investigators across the country and is now being passed down to a new generation of prostate cancer investigators.

8 Prostate Cancer Foundation 2006 Progress Report 9 C o m m i t m e n t t o S c i e n t i fi c Pr o g r e s s

T h e c h a l l e n g e s t h a t f a c e t h e p r o s t a t e c a n c e r r e s e a r c h c o m m u n i t y t o d a y a r e n o l e s s d i f f i c u l t t o o v e r c o m e t h a n t h e y w e r e 1 3 y e a r s a g o w h e n t h e P r o s t a t e C a n c e r F o u n d a t i o n w a s s t a r t e d . P r o s t a t e c a n c e r r e m a i n s a c o m p l e x d i s e a s e , th e S e n i o r r e s e a r c h m a n a g e r s a t m a j o r b i o l o gy o f w h i c h i s d i ffi c u l t t o u n d e r s t a n d . An d b i o p h a r m a c e u t i c al c o m p a n i e s a n d th e C E O o f i t s h e t e r o g e n e o u s n a t u r e a n d s l o w , u n p r e d i c t a b l e a m a j o r c a n c e r c e n t e r s e rv e d a s m e m b e r s o f a n a n d p e r s i s t e n t g r o wth p a t t e r n s d e fy th e s t a n d a r d I n d e p e n d e n t E xp e rt R e vi e w P a n e l , w h i c h w a s t r e a t m e n t a p p r o a c h e s u s e d i n o th e r c a n c e r s . T h i s t a s k e d wi th e v al u a t i n g th e f e e d b a c k r e c e i v e d fr o m i s w h y c o n t i n u e d e ff o rt s b y d e d i c a t e d P C F s c i e n t i s t s th e r e s e a r c h c o m m u n i ty a n d s u b m i t t i n g th e t o b e t t e r u n d e r s t a n d h o w p r o s t a t e c a n c e r d e v e l o p s r e c o m m e n d e d s t r a t e g i e s t o th e B o a r d o f D i r e c t o r s . a n d s p r e a d s i s s o i m p o rt a n t . All o f th e p a rt i c i p a n t s , i n c l u d i n g th o s e a t B a i n & C o m p a n y , w o r k e d o n a p r o b o n o b a s i s a s a I d e n t i fy i n g N e w S t r a t e g i c t e s t a m e n t t o th e i r c o m m i t m e n t t o th e P C F , a n d O p p o rt u n i t i e s f o r t h e P C F th e i r r e c o g n i t i o n o f th e p r o f o u n d r o l e th a t th e P C F I n l a t e 2 0 0 5 , th e P C F l a u n c h e d a n e xt e n s i v e c a n p l a y i n th e p r o s t a t e c a n c e r r e s e a r c h a r e n a . s ix -m o n th e ff o rt t o g a i n i n s i g h t fr o m i n v e s t i g a t o r s i n th e fi e l d a b o u t w h a t th e P C F c o u l d d o t o h e l p th e m m o v e th e i r r e s e a r c h f o rw a r d m o r e r a p i dl y . T h e e ff o rt , l e d b y th e P C F B o a r d o f D i r e c t o r s a n d B a i n & C o m p a n y , f o c u s e d o n i d e n t i fyi n g n e w s t r a t e g i e s th a t b u i l d u p o n th e P C F ’s u n i q u e c a p a b i l i t i e s t o m o v e th e e n t i r e fi e l d f o rw a r d . M o s t i m p o rt a n t , i m p l e m e n t a t i o n o f s p e c i fi c g o al s a n d m i l e s t o n e s t o m e a s u r e th e s e g o al s w o u l d all o w th e P C F t o r a p i dl y r e vi e w i t s p r o g r e s s a n d a d j u s t i t s s t r a t e g i e s a n d i n v e s t m e n t o f r e s o u r c e s m o r e wi s e l y .

S c o t t H a h m a t w o r k i n t h e l a b o r a t o ry o f P C F -f u n d e d i n v e s t i g a t o r R o b e rt E. R e i t e r , M D .

10 Prostate Cancer F oundation 2006 Pro gress Report 11 At the conclusion of the review process, the 3. Identifying Better Markers of Disease Progression PCF’s Board of Directors unanimously endorsed In prostate cancer, reliable markers of disease the recommendations to focus on the following progression for making treatment decisions are three areas: urgently needed. Thus, clinical trials of new drugs typically run for five years or more to show a survival 1. Promoting Innovation in Prostate Cancer Research benefit and, on occasion, have closed early because Over the years, the PCF has taken pride in the duration of the trial was too long to determine encouraging and providing funding for investigators whether a clinical benefit would ultimately be seen. to explore new avenues of research. Unfortunately, funding for these proof-of-concept experiments A new generation of biotechnological advances is increasingly difficult to obtain. Thus, it is more in the past few years now enables investigators to important than ever that the PCF expand its role in begin identifying markers that will signal – within promoting innovation in prostate cancer research. weeks or months – whether the drug is working and The PCF will grant multi-year awards consisting of reasonably predict long-term outcomes. greater amounts of money – enabling investigators to Investigators working in this area recognize the commit more time to science and less time to raising need for collaboration to efficiently advance these needed funds. markers into clinical trials and recognize the need 2. Translating More Concepts and Compounds for the PCF to lead this effort. Capitalizing on its into Clinical Trials unique, independent position in the research arena, Because clinical trials evaluating new drugs for the PCF will survey the landscape of progression prostate cancer often take longer and require the markers for prostate cancer, begin to establish criteria enrollment of more patients than do trials for other for effective markers, facilitate collaboration among cancers, it is not surprising that biopharmaceutical investigators and assist in overcoming institutional companies rarely make prostate cancer a high and regulatory obstacles. priority for early clinical trials. Advancing the Cure Yet, when proof-of-concept experiments and With the implementation of the PCF’s three early-phase trials show that a drug is effective and initiatives, the landscape of prostate cancer research safe, biopharmaceutical companies frequently decide will dramatically shift toward increased investment, to commit the necessary resources to the clinical prioritization and enthusiasm for innovative development of new agents for prostate cancer. solutions to the problem. All of this work is focused In continuous collaboration with investigators at on the PCF’s central goal: to find better treatments major academic institutions, the PCF will drive and a cure for recurrent prostate cancer. efforts to identify and prioritize therapeutic compounds that should be tested in prostate cancer and move them rapidly through the first round of proof-of-concept and early-phase trials. With results from these studies in hand, the PCF will work with clinical trial consortia, biopharmaceutical companies and governmental agencies to ensure that these compounds are tested in men with prostate cancer.

10 Prostate Cancer Foundation 2006 Progress Report 11 PLAYER Gov ernment Ag encies NO. 4 Scientific- Total n umber Retreat of gov ernment ag encies w orking with the PCF The Prostate Cancer Foundation partners with state and federal government agencies to harness availa ble resources and support multi-institutional prostate cancer research programs across the country.

R e p r e s e nt at iv e s f r o m s t at e a n d f e d e r a l g o v e rn me nt a g e nc ie s w ho p a rt ne r w it h t h e P C F.

Congressionally Directed Medical Research Programs

12 Prostate Cancer Foundation 2006 Progress Report 13 Father’s Day 2006

Every year, the Prostate Cancer Foundation celebrates men and their families by using the Fatherʼs Day holiday to honor men who are battling prostate cancer, educate those who are at risk of getting the disease and raise much-needed funds for research through targeted campaigns. In 2006, the PCF continued to work with long-term supporters Safeway and Major League Baseball and enlisted a new partner, Gillette and its Gillette Prostate Cancer Challenge program.

Major League Baseball Safeway Since 1997, Major League Baseball (MLB) and the Celebrating six years of working with the PCF, Major League Baseball Players Association have Safeway and its family of premier food retailers taken a swing against prostate cancer by teaming up raised a record $5.1 million for prostate cancer w ith the PCF for the Home Run Challenge, raising research from Memorial Day through July 4th. more than $28 million for prostate cancer research. Led by Steve Burd, president and chief executive During the week of Father’s Day, MLB teams raise off icer of Safeway, the company-wide campaign money from fans and sponsors who pledge money included point- of- purchase donation opportunities for each home run hit in 60 selected games. at more than 15,000 checkout stands in all 1,700 Safeway stores. This long- standing partnership has In 2006, 153 home runs were hit and nearly $2.5 raised more than $17.6 million for prostate cancer million was raised for prostate cancer research, with investigators throughout the world. 42 home runs on Father’s Day alone. Baseball legends Reggie Jackson, Dennis Eckersley and Tommy Gillette Prostate Cancer Challenge Lasorda serve as Home Run Challenge Goodwill Joining the ranks of PCF supporters, in 2006 Gillette A mbassadors and made appearances across the sponsored several elements of the PCF Home Run countr y to raise awareness of prostate cancer and Challenge and helped conduct a Father’s Day national encourage people to make a pledge. In addition, men’s health survey, which highlighted the FOX Networks, Horizon Media, Turner lack of knowledge about prostate cancer Broadcasting and Cablevision and the critical role women can play in generously donated advertising educating their loved ones. space to publicize the program A mong many interesting findings, to potential donors. the PCF/Gillette Men’s Health Survey revealed that nearly three - quarters (72%) of men said they would be very likely to tal k to their doctors about prostate cancer if asked by the women in their lives. Yet only half of women believe they have that k ind of inf luence. The print and broadcast media coverage reached a potential combined audience of

Mike Milken and Screech, mascot for the Washington more than 25 million people, educating millions of Nationals, team up to raise prostate cancer awareness. A mericans about the PCF, prostate cancer and the need for research funding.

12 Prostate Cancer Foundation 2006 Progress Report 13 PLAYER Athletes for a Cure NO. 450Scientific - Total number Retreat of athletes participating Hundreds of professional and amateur athletes across the country teamed with the Prostate Cancer Foundation to raise awareness about prostate cancer and to raise funds for research.

Kevin Trock Bill Bell

Petranek Fitness, CrossFit Los Angeles

14 Prostate Cancer Foundation 2006 Progress Report 15 Athletes for a Cure

A new program was launched in 2006 to assist athletes in endurance sports to increase awareness of prostate cancer and raise money for prostate cancer research. Within months, 400 “athletes for a cure” ran, swam, bi ked and lif ted weights to raise more than $350,000 – w ith the help of the Wade F. B. Thompson Matching Grant – for prostate cancer research. A new website, www.athletesforacure.org, was a lso developed to create a home in the racing and f undraising communit y and prov ide athletes w ith multiple tools to set donation goa ls; upload photos, persona l stories and race information ; and send emails to their f riends and family.

The program was caref ully designed to give athletes the abilit y to raise money for prostate cancer research as part of any race event in which they are participating, a lthough Athletes for a Cure worked closely w ith severa l designated events, including USA Triathlon, the Los A ngeles Triathlon and CrossFit g y m aff iliates. In addition, severa l professiona l athletes proud ly wore the Athletes for a Cure logo during their respective races, and dozens of current and new professiona l athletes Dean Matsuda and kids are lined up to participate in 2007.

14 Prostate Cancer Foundation 2006 Progress Report 15 PLAYER Business NO. 15 - Total number of corporate organizations with whom the PCF has partnered The Prostate Cancer Foundation is proud to count many prominent companies and organizations as par tners in the effor t to find better treatments and a cure for recurrent prostate cancer. Forging Collaborative Partnerships

More than t wo million American men and their families are battling prostate cancer. It is a disease that affects countless families and communities which, in turn, touches ever yone. To help reach as many people as possible, in 2006 Examples of the PCF’s recent collaborations include: the Prostate Cancer Foundation continued to HUGO BOSS develop significant partnerships w ith corporations In 2006, HUGO BOSS, the maker of f ine men’s and and organizations w ith the mutua l goa l of ma k ing women’s clothing, hosted a private shopping event in a quantum leap for ward in the fight against this nine of its retail stores across the country, including disease. With their suppor t, the PCF has raised the Columbus Circle store in New York City and the more than $ 288 million, including $ 27 million Rodeo Drive store in Beverly Hills. Guests were able in 2006 a lone. to view the BOSS Black, BOSS Orange and HUGO Fall/Winter 2006 collections and spin a wheel for a chance to win several prizes, including HUGO BOSS gif t certif icates. Fif teen percent of the evening’s proceeds benef ited the PCF, and HUGO BOSS repre- sentatives also presented a $50,000 check to the PCF. Since 2004, HUGO BOSS in -store events have raised nearly $150,000 to help find better treatments and a cure for prostate cancer.

Debbie Bohnett, Chief Operating Off icer of the Prostate Cancer Foundation, accepted a $ 50,000 check from HUGO BOSS at the Columbus Circle store in New York City. HUGO BOSS representatives shown with her are, left to right, Bill Scott, Chief Operating Off icer ; Tony Lucia, Chief Executive Off icer ; and Vince Kavanaugh, Vice President of Retail Operations.

16 Prostate Cancer Foundation 2006 Progress Report 17 G i o r g i o A r m a n i S i n c e 2 0 0 5 , G i o r g i o A r m a n i , o n e o f t h e w o r l d’s l e a d i n g f a s h i o n a n d l u x u ry p u rv e y o r s , h a s t e a m e d w i t h t h e P C F t o r a i s e c r u c i a l f u n d s f o r p r o s t a t e c a n c e r r e s e a r c h . G i o r g i o A r m a n i , i n p a rt n e r s h i p wi th E s q u i r e, h o s t e d a p r i v a t e s h o p p i n g e v e n t i n i t s B e v e r l y H i ll s s t o r e i n 2 0 0 6 . G u e s t s w e r e a b l e t o vi e w th e M e n ’s M a d e t o M e a s u r e c o ll e c t i o n . F i ft e e n p e r c e n t o f th e e v e n i n g ’s p r o c e e d s , al o n g wi th i t e m s p u r c h a s e d f o r tw o w e e k s th e r e a ft e r , b e n e fi t e d th e P C F . I n a d d i t i o n , p r o c e e d s fr o m th e t i c k e t s al e s o f a l ux u ry r a ffl e L e s l i e D . M i c h e l s o n , P C F B o a r d M e m b e r a n d f o rm e r C h i e f E x e c u t i v e O f fi c e r , p a c k a g e w e r e d o n a t e d t o th e P C F . a n d b a s k e t b a l l l e g e n d K a r e e m A b d u l - J a b b a r j o i n A n d r e A l d ri d g e o f N B A T V a n d K a t h y B e h r e n s , S e n i o r V i c e P r e s i d e n t o f C o m m u n i t y a n d P l a y e r P r o g r a m s f o r t h e N B A , i n s u p p o rt o f p r o s t a t e c a n c e r r e s e a r c h .

N B A F o r t h e fi r s t t i m e , t h e P C F p a r t n e r e d w i t h t h e N a t i o n a l B a s k e t b a l l A s s o c i a t i o n ( N B A ) a n d i t s N B A C a r e s i n i t i a t i v e t o o ff e r s p e c i a l-e d i t i o n N B A p l a y e r w r i s t b a n d s . T h e d i ff e r e n t w r i s t b a n d s f e a t u r e d 1 8 s t a r s a n d l e g e n d s w i t h t e a m c o l o r s , p l a y e r n a m e s , p l a y e r s i g n a t u r e s a n d u n i f o r m n u m b e r s . S o m e o f t h e c u r r e n t a n d f o r m e r N B A p l a y e r s w h o p a r t i c i p a t e d i n t h e p r o g r a m i n c l u d e L e B r o n J a m e s ( C l e v e l a n d C a v a l i e r s ) ; C a r m e l o A n t h o n y ( D e n v e r N u g g e t s ) ; K a r e e m A b d u l- J a b b a r a n d J e r ry W e s t L e s l i e D . M i c h e l s o n , P C F B o a r d M e m b e r a n d f o rm e r C h i e f E x e c u t i v e ( L o s A n g e l e s L ak e r s ) ; S h a q u i l l e O ’ N e a l a n d D wy a n e O f fi c e r , i s j o i n e d b y f e l l o w s u p p o rt e rs o f p r o s t a t e c a n c e r r e s e a r ch : S p e n c e B o v e e , S e n i o r V i c e P r e s i d e n t o f M a r k e t i n g o f E x o d u s F i l m W a d e ( M i a m i H e a t ) ; W a l t F r a z i e r ( N e w Yo r k G r o u p ; T y l e r B a rt h , G i o r g i o A rm a n i E v e n t C o - c h a i r; a n d K e v i n O ’ M a l l e y , K n i c k s ) ; a n d T i m D u n c a n , G e o r g e G e rvi n a n d P u b l i s h e r o f E s q u i r e m a g a z i n e . To n y P a r k e r ( S a n An t o n i o S p u r s ) . T h e i n d i vi d u al wr i s t b an d s w e r e s o l d a t p a rti c i p a ti n g a r e n a s , th e N B A S t o r e i n N e w Yo r k C i ty an d o nl i n e a t N B A S t o r e . c o m an d www . p r o s t a t e c an c e rf o u n d a ti o n . o r g .

16 Prostate Cancer F oundation 2006 Pro gress Report 17 PLA YER Pub lic F igures NO . 3 0 0 - P u b l i c Scientific fi g u r e s w h oRetreat h a v e j o i n e d t h e P C F i n t h e fi g h t a g a i n s t p r o s t a t e c a n c e r SinceLore inceptioneu faccum of the volore Prostate tem Cancer zzrit Foundation, at, sed multiplete ver inibhprominent el iurem figures zzriure in politics, eliquisi.Lor sports, film sum and television ha v e proudldolorpero y lent their odoloborem time and support vercil to ent help venisis raise much-needed ad tio dolor. funds Lorefor prostate eu faccum cancer volo-reresearch. tem zzrit at, sed te ver inibh el iurem

Whoopi Gold berg

L eft to right: Dona ld T ru mp, Mike Mil ken , Don King a nd Bil l O’ Reil ly

K atie Cou ric a nd Mike Mil ken

Quinc y Jones a nd Ah mad R ashad

Joe Torre and Tommy Lasorda

18 Prostate Cancer Foundation 2006 Progress Report 19 Arnieʼs Army Battles Prostate Cancer Lamkin Grips Since 2002, the PCF has worked with Arnie’s Army Lamkin, the premier maker of golf club grips, on one- day events built around a closest-to- the- pin partnered with the PCF for “Grips for Life,” a contest on a par-3 hole. Banners, posters, pin flags program created with Arnold Palmer that donates and other collateral materials carr y the program a portion of all proceeds from domestic Lamkin logo and all golfers are encouraged to join Arnie’s branded grip sales to help fund prostate cancer Army to help win the battle against prostate cancer. research. Lamkin has made a goal to raise at least To date, Arnie’s Army has sponsored nearly 2,000 $150,000 annually for prostate cancer research, and events, raising more than $1.3 million in the fight in 2006, the program surpassed the $300,000 mark against prostate cancer. in donations to the PCF.

Golf Digest Celebrity Invitational Champions Tour for the Cure Golf Digest magazine hosted its second annual Golf Co - chaired by Arnold Palmer, Jim Colbert and Ray Scientific Retreat Digest Celebrity Invitational at the Wilshire Countr y Floyd, Champions Tour for the Cure urges golf fans Lore eu faccum volore tem zzrit at, sed te ver inibh el iurem zzriure eliquisi.Lor sum Club in Los Angeles to benefit the PCF. Event to pledge $1 or more for each birdie made by their dolorpero odoloborem vercil ent venisis ad tio dolor. Lore eu faccum volo-re tem zzrit at, sed sponsors Ashworth, Cobra, Ketel One Vodka te ver inibh el iurem favorite Champions Tour players throughout the and Porsche helped raise nearly $200,000. season. Every birdie made between the MasterCard Hosted by Arnold Palmer and in support of Arnie’s Championship in mid-Januar y and the Charles Army Battles Prostate Cancer, the event featured Schwab Cup Championship in late October supports musicians and celebrities from TV and film paired prostate cancer research. Since 1998, the Champions w ith amateur golfers. Twent y- f ive celebrities Tour for the Cure has raised more than $4.5 million participated, including Richard Schiff, Kenny G. and to support prostate cancer research. Engelbert Humperdinck. Mart y Rubino, a cancer surv ivor with a 25 handicap, made a hole in one and won a 2007 Porsche Cayenne. In just two years, the Golf Digest Celebrity Invitational has raised more than $360,000 for prostate cancer research.

Ar nold Palmer, Kenny G. and featured musicians and celebrities from television and film at the Golf Digest Celebrity Invitational.

18 Prostate Cancer Foundation 2006 Progress Report 19 Fundraising Events

Prostate Cancer Foundation fundraising events seek to involve as many people as possible in the fight to find better treatments and a cure for prostate cancer. Supporters of the PCF come together to raise much-needed funds while also enjoying the camaraderie of others and updates about the PCF and its funding research efforts. In 2006, PCF fundraising events included golf and A Night to Remember tennis tournaments, formal dinners and other Featuring gourmet food, delicious wines and specialty programs. Highlights include: an energetic live auction, the annual A Night to Remember event raised nearly $1 million for prostate cancer research. Hosted by Marvin Shanken, editor of Wine Spectator, the event was held at the Four Seasons Restaurant in New York City. Since inception, A Night to Remember has raised $6.7 million for the PCF.

Hamptons Pro-Am Tennis Invitational David and Julia Koch welcomed the PCF back for a second year for a round-robin tennis tournament at the East Hampton Indoor & Outdoor Tennis Club in New York and a spectacular Pairings Party at their José Feliciano and Tony Bennett performed together at a benefit home. The weekend raised $1 million for the PCF’s for the PCF held at DANIEL in New York City. research efforts.

Ellis Ferreira, left, 2000 Australian Open Doubles Champion An Evening at DANIEL and 2000 US Open Doubles Finalist, partnered with Jerry Katell Guests of An Evening at DANIEL, held at the at the Hamptons Pro-Am Tennis Invitational. renowned French restaurant in New York City, rang in the 2006 holiday season by tasting award-winning Chef Daniel Boulud’s extraordinary cuisine and listening to the music of Tony Bennett and José Feliciano – a first-ever duet by these music legends. The first-time event raised more than $1.3 million for the PCF.

20 Prostate Cancer Foundation 2006 Progress Report 21 Alex O’Brien, left, winner of the 1999 US Open and ATP World Doubles Championship, partnered with Thomas Virtue for the Carl H. Lindner Pro-Am Invitational Tennis Tournament.

Carl H. Lindner Pro-Am Invitational Tennis Tournament Hosted by Donald Trump at his Mar-a-Lago Club in Palm Beach, Florida, the round-robin tennis tournament drew a star-studded field of former tennis pros including Jared Palmer, David Adams and Brian MacPhie. Guests enjoyed the stand-up comedy of Jay Leno and the auction of a Metropolitan Choppers custom motorcycle for $110,000. In total, more than $700,000 was raised for prostate cancer research.

Wynn Las Vegas Invitational Weekend Hosted by Steve and Elaine Wynn, the Wynn Las Vegas Invitational Weekend highlighted the best in dining, entertainment, the arts and other specially designed experiences. The two-day golf tournament featured several legends of NBA basketball, including Julius “Dr. J” Irving, Rick Barry and John Salley. Lowell Milken, left, Chairman and Co-Founder of the Milken Highlights of the weekend included a dance lesson Family Foundation, is joined by actor Greg Kinnear and from some of the stars of “Dancing with the Stars” PCF Board Member David Epstein at the Wynn Las Vegas Invitational Weekend supporting prostate cancer research. and a special luncheon with designer Zac Posen. The event benefited the PCF and generated nearly $2 million for prostate cancer research.

20 Prostate Cancer Foundation 2006 Progress Report 21 PLAYER Donors NO. 67,000 - Donors since inception The generous support of 67,000 donors has enabled the Prostate Cancer Foundation to support critical research – and every dollar raised has moved us closer to finding better treatments and a cure for recurrent prostate cancer.

Bob Each and family David Higger and his daughter, Ronni Dav id H. a nd Ju l ia K och

Sherma n M i l ler a nd f a mi ly Ed Si l ha n a nd f a mi ly

22 Prostate Cancer Foundation 2006 Progress Report 23 Broadening the Base of Vital Support

In 2006, the Prostate Cancer Foundation nearly doubled its base from the previous year, expanding from 13,000 total donors in 2005 to 24,000 in 2006. Across the nation, the PCF continues to educate Wade F. B. Thompson Matching Grant and inform various audiences, including donors, For the second year prostate cancer survivors and their families, and the in a row, PCF general public, about the PCF as an organization and donors generously its mission, prostate cancer statistics and the need responded to a for increased funding of prostate cancer research. matching grant by These communications efforts included a quarterly Wade F. B. newsletter, Focus, frequent website refreshes and Thompson, a updates, NewsPulse email news alerts, science updates prostate cancer, and more. melanoma and colon cancer survivor. In addition, amplified public relations efforts helped Wade F. B. Thompson increase visibility, awareness and education about Thompson, prostate cancer and the PCF. In 2006, the PCF secured chairman, president more than 500 print, broadcast and online media and chief executive officer of Thor Industries, Inc., placements, a 150% increase from the year before. has dedicated himself to defeating cancer. Of many visible placements, the most noteworthy More than 8,500 PCF donors generously included The New York Times, AARP Magazine, contributed $755,000 to the Wade F. B. Thompson Business Week, The Wall Street Journal, FORTUNE Matching Grant, exceeding the $500,000 goal. magazine, New York Post, Good Housekeeping, Sports Thompson matched the entire amount, resulting in Illustrated, Seventeen magazine, Reuters and Scripps a total of more than $1.5 million raised for prostate

PCF Inception-to-Date Donors (1000s) Howard News Service. cancer research.

13 12 The 2006 Competitive Awards Program immediately 11 10 Donors Since Inception (thousands) benefited from the newly raised funds generated by 9 8 the match, enabling the PCF to invest in many more 24 7 promising research projects. Because of the extra 6 22 5 funds available this year compared with last year, 17 4 20

3 18 more investigators received funds for their research 2

1 16 projects in a diverse range of topic areas including 0 ʼ93 ʼ94 ʼ95 ʼ96 ʼ97 ʼ98 ʼ99 ʼ00 ʼ01 ʼ02 ʼ03 ʼ04 ʼ05 ʼ06 14 genetics, biomarkers, immunotherapy and nutrition.

12

10

8

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22 Prostate Cancer Foundation 2006 Progress Report 23 A Special Thank You

The Prostate Cancer Foundation would like to thank everyone who has supported us over the years. We gratefully acknowledge the following individuals, foundations, corporations and others who have given at least $5,000 since our inception. Clifton S. Robbins Charitable Fund The Lynn Aymar Family Foundation Bruce R. and Jolene M. McCaw Fund Founders Ellen and Richard V. Sandler, Esq. Chris and Tory Bagdasarian George A. Mealey ($50,000,000+) Milken Family Foundation Sanofi-Aventis Charles F. Baird, Jr. Robert A. Meister Jane and Terry Semel Robert and Donna Baldwin MidOcean Partners David E. and Beth Kobliner Shaw Charles and Michelle Becker Avram Miller Founderʼs Circle Lester and Sue Smith Foundation Marc R. Benioff S. Leslie and Barbara Misrock ($2,000,000 - $49,999,999) Anonymous (2) Edward M. Snider Braman Family Foundation Kenneth and Julie Moelis David and Julia Koch Stuart Subotnick Eli & Edythe L. Broad Foundation Moore Family Foundation Thomas H. and Ann Tenenbaum Lee Michael L. and Lynne Tarnopol Gary S. Broad John and Rebecca Moores Carl Lindner Stanley and Barbara Zax John and Barbara Burns Jay and Elaine Moorin, Lowell Milken August A. Busch, IV Alain and Iris Schreiber, and Michael and Lori Milken Patrons California State Council of Laborers ProQuest Investments Ely R. Callaway Marc and Jane Nathanson The News Corporation Foundation ($250,000 - $499,999) Stewart and Lynda Resnick Anonymous (1) Wayne Calloway Nativity Jesuit Middle School Linden Nelson Safeway, Inc. Joseph and Annette Allen CAO International, Inc. George and Sandra Norcross Stephen and Elaine Wynn Robert K. Barth Cendant Corporation John and Sally Nordstrom Brian and Kathleen Bean John and Jennifer Chalsty James and Patricia Cayne Max C. Chapman, Jr. OSI Pharmaceuticals Leadership Circle Stephen and Chantal Cloobeck David S. Collins Palermo Ravich Family Foundation ($1,000,000 - $1,999,999) Condé Nast Publications, Inc. Concern Foundation Joel M. Pashcow Anonymous (5) L. John Doerr The Carole & Robert Daly Rick Pitino Abbott Laboratories David and Marsha Ederer Charitable Foundation Bruce I. Raben Aventis Pharmaceuticals, Inc. Christian B. Evensen Thomas and Gun Denhart Ramapo Trust Leon and Debra Black The Gillette Company James and Kristin Dolan Sumner and Paula Redstone Bristol-Myers Squibb Company Howard Gittis Dunwoody Senior Men’s Golf Association Brian and Patricia Reynolds Jamie B. Coulter Phillip and Lyn Goldstein Jeremy D. Eden William A. Richardson Charles F. Dolan David and Sheryll Harkins Charitable Gift Fund Don Engel Leonard and Louise Riggio William L. Edwards Heinz North America Ernst & Young LLP Lew Rothman Edward P. Evans Foundation Steven and Tomisue Hilbert William F. Farley Marc J. and Carolyn Rowan Andrew S. Grove The R.D. and Joan Dale Hubbard Ralph and Cynthia Finerman Lewis and Rachael Rudin Sidney Kimmel Foundation M. Anthony and Anne Fisher Larry W. Ruvo Rush Limbaugh Ray and Ghada Irani Sidney E. Frank Haim and Cheryl Saban The Lincy Foundation Michael Jordan Richard S. Fuld, Jr. San Francisco Giants Charles N. Mathewson Foundation Peter Karmanos, Jr. Friendship Foundation, Inc. The John F. Scarpa Foundation The Craig and Susan McCaw Foundation Charles G. Koch The David Geffen Foundation David and Janelle Shaffer Kerry Packer Herb and Natalie Kohler Richard and Phyllis Gelb J. Gary and O.J. Shansby Foundation Nelson and Claudia Peltz/Triarc Companies, Inc. C. Michael and Elizabeth Kojaian Gen-Probe Incorporated Silent Partners Inc. Ronald O. Perelman Robert A. Kotick Eric and Anne Gleacher Jeffrey and Lisa Silverman PGA Tour Charities, Inc. Lamkin Corporation Thomas and Holly Gores Eric and Susan Smidt Julian H. Robertson, Jr. F W McCarthy Foundation Greenbriar Golf Association Shoes for Crews William A. Schwartz Richard Mejasich Orland S. Greene David M. Solomon M. Shanken, Chairman Joy and Jerry Monkarsh Family Foundation Wayne and Janet Gretzky Martin & Toni Sosnoff Foundation M. Shanken Communications, Inc. Bruce and Jeannie Nordstrom Martin and Audrey Gruss Alex G. Spanos Thomas Spiegel Allen and Madeleine Paulson Guggenheim Investment Management, LLC Avy and Marcie Stein Taste for Living Sandra and Lawrence Post Richard B. Handler Joseph and Diane Steinberg Ted and Dani Virtue Family Foundation Joseph W. Harch 1992 Charitable Trust Wade F. B. Thompson Gene and Marianne Salmon Thomas O. Hicks Ernest E. Stempel Charitable Foundation Sanofi-Synthelabo Hilton Hotels Corporation The Stern Family Foundation Martin and Pamela Wygod Mickey and Karen Shapiro Leo Hindery, Jr. Roger and Susan Stone Melvin and Bren Simon Hugo Boss Fashions, Inc. Swing for the Cure Benefactors Charitable Foundation No.1 Jon and Karen Huntsman Marty Tenenbaum ($500,000 - $999,999) Paul and Elle Stephens Carl and Gail Icahn Laurence and Billie Tisch Anonymous (2) Sterling Equities Peter W. Janssen Tom and Diane Tuft Advance Magazine Group Warren and Jale Trepp Richard and Deborah Justice Van Van Auken Baume & Mercier Co. Clyde T. Turner Mel and Terry Karmazin The Wagner Family Foundation The Bunker Foundation Leslie L. Vadasz David Karpol Raul and Vicki Walters Ronald W. Burkle Varian Medical Systems, Inc. Solomon Kerzner Wasserman, Comden, Casselman & Pearson, LLP Winston H. Chen, PhD Robert and Angela Voss Michael and Jena King Will Weinstein Lawrence J. Ellison Dennis and Phyllis Washington Kissick Family Foundation Thomas and Emily Weisel Sue Gin Gary and Karen Winnick W. C. Klintworth John F. Welch, Jr. D. Wayne and Anne Gittinger Knowledge Universe Jim and Kim Williams Sam and Helen Zell Golfers Against Cancer Partners Kovler Family Foundation The Greenspun Family Foundation Selig Zises ($100,000 - $249,999) W. Howard and Mary Lester Kern Family Fund Anonymous (1) Solomon and Rosie Lew Carol and Earle I. Mack William and Donna Acquavella Peter B. Lewis Associates Richard N. Merkin, MD The G. Chris Andersen Family Foundation William and Phyllis Mack ($50,000 - $99,999) Gordon E. Moore Phillip and Nancy Anschutz Major League Baseball Charity, Inc. Anonymous (4) Novartis Pharmaceuticals Corporation Ambassador George L. Argyros, Sr. Jeffrey A. Marcus Robert W. Adler Lewis and Peg Ranieri Arnie’s Army Battles Prostate Cancer Leni and Peter May Edward C. Allred

24 Prostate Cancer Foundation 2006 Progress Report 25 Altadis USA, Inc. Laborers’ International Union Gregory White GPC Biotech Eric J. Aronson of North America David Yandry Mr. and Mrs. Kenneth B. Hamlet Arthur J. Gallagher & Co. Emeril Lagasse Don Yannias John J. Hannan Marlene and Michael Aufrecht Charitable Fund Kenneth and Linda Lay Zapolin Transactional Ventures, Inc. Reed L. Harman Facundo L. Bacardi The Leeds Family Foundation William Hartnett Lehman Brothers, Inc. Ralph and Kay Hemingway Roger Barnett Friends Robert Levin John and Susan Hess Ron and Judy Baron ($25,000 - $49,999) The Cecile and Fred Bartman Foundation Robert E. Linton Anonymous (2) Samuel J. Heyman Kathy and Frank Baxter Ira A. Lipman Don Ackerman Kenneth and Janet Himmel Erin and Douglas Becker Laurence and Karen Mandelbaum Neale M. Albert, Esq. Charlie J. Horky Samuel Belzberg Michael Marek Norman E. Alexander Charles and Barbara Hurwitz Marshall Bennett Margaritaville Holdings, LLC Allchin Foundation The Iacocca Foundation Ken Berg Joseph and Anne McCann Arby’s Vincent Iorio Phyllis and Martin Berman John E. McCaw Frank J. Arcella IRI Golf Management, LP Robert and Catherine Beyer Richard McKenzie, Jr. Roland E. Arnall Steve and Ellen Jackson Frank and Carol Biondi, Jr. Barry Meyer AstraZeneca Stanley R. Jaffe BlackRock Financial Management, Inc. Millennium Pharmaceuticals, Inc. Mr. & Mrs. Robert Baker Family Foundation Gerald Katell Dan Blumenthal Michael Minikes Robert Bales The Fritz and Adelaide Kauffman Boston Red Sox Edward J. Minskoff Jude T. Barbera, MD Foundation, Inc. Jerry Brassfield Morongo Band of Mission Indians David and Judy Oliver Bash Stephen and Marina Kaufman Shann Brassfield Native American Rights Fund Vera Wang and Arthur Becker KB Home Gresham T. Brebach, Jr. Movado Group, Inc. Robert A. Belfer J. Christopher Kennedy Steven A. Burd Angelo R. Mozilo Art H. Bilger Michael Klein Frank Caufield Ken Nees Les and Sheri Biller Henry R. Kravis Ray and Patti Chambers Neiman Marcus Direct Bobby Blair Benjamin V. Lambert Alfred and Kathryn Checchi James Newman Bloomberg L.P. Bill Lane, Jr. Chicago White Sox Phil R. North Bluefish Concierge, Inc. Gerrity Lansing Marshall and Maureen Cogan Ruth Ornest David Booth Bennett and Jerri Lebow Jerry and Adrianne Cohen Jon Otto Tony Borhani Steve Lehman Robert and Beverly Cohen The Palin Family Foundation, Inc. Denis A. Bovin Joseph Rob Link Family Foundation Jim Pattison Harry M. Brittenham, Esq. Joe Lumarda Ethan Penner Susan E. Lynch James H. Coleman Coco Brown The Picower Foundation Gene E. Lynn Countrywide Credit Industries Thomas and Jo Anne Bruno Pritzker Foundation Donald and Hilda Lytton Dendreon Corporation John M. Bryan Martin and Patricia Raynes David S. Mack Michael D. Dingman Brian P. Burns Richard S. Ressler Fredric Mack Robert and Tricia Earl Dick and Lisa Cashin Tony Ressler and Jamie Gertz Charitable Gift Fund Harvey Mackay Bruce Eichner Meshulam Riklis Circle “M” Enterprises Bernard L. Madoff Lee and Daniele Einsidler The Riordan Foundation Andrew S. Clare Bernard Marcus David J. Epstein George R. Roberts Brian and Denise Cobb Howard and Nancy Marks Mr. and Mrs. Robert S. Evans Allan V. Rose Gregory and Monica Coleman Stanley and Pamela Maron William B. Finneran The Rose Foundation Howard Cox Robert and Joan Masterson First Data Western Union Foundation Andrew M. Rosenfield Lester and Renee Crown Harold Matzner and The Safeway Foundation Pat and E. John Rosenwald Edgar and Elissa Cullman Keith W. McCaw David and Judith Fleischer Steven and Daryl Roth Ian M. Cumming Michael McKeever Paul M. Fleming Eric Rothfeld Davidoff of Geneva Dennis Mehiel Forester Family Foundation Peter H. Rothschild Robert and Kelly Day Jerome Meislin Theodore J. Forstmann Mike Ryan Celine Dion Foundation Merck and Co., Inc. Michael Frey salesforce.com/foundation Mark Donnelly Herman and Susan Merinoff Gantcher Family Philanthropic Fund Ronald Salkow Michael Dougherty Harold M. Messmer, Jr. Jeffrey D. Gargiulo and Valerie Boyd Allen B. Schwartz Efficiency Enterprises Theodore N. Miller Arthur and Linda Gelb Stephen A. Schwarzman Harvey P. Eisen James F. Moore Jay Geldmacher Harvey L. Silbert, Esq. Lewis M. Eisenberg Robert E. Morrow Henry and Arline Gluck Jeffrey and Helaine Silverstein Lawrence R. Elins Mark E. Mortimer Stanley P. Gold Herb Simon The Entertainment Industry Foundation Stuart W. Moselman Jeremy P. Goldberg William E. and Tonia Donnelley Simon Faith, Love, Hope, Win Foundation Netjets Aviation, Inc. Richard and Marcia Goldberg Paul and Celia Sirotkin Thomas J. Fazio Joseph Neubauer John and Kathleen Gorman Stuart M. Sloan Ferolito, Vultaggio & Sons Aviv Nevo William and Susan Gross Jeff P. Smith Cary Fields L. Mark Newman The Sam and Sarah Grossinger Foundation Don Soffer Steve Fink New York Mets Foundation, Inc. Allen Grubman Southern California District Alex Fisher John Nickoll Norb Guziewicz Council of Laborers Peter E. Fleming, Jr. T. D. O’Connell J. Ira and Nicki Harris The John R. & Inge P. Stafford Foundation Todd Follmer Chris K. Olander Alan and Vivien Hassenfeld Saul P. Steinberg Theo and Constance Folz Pierre and Pam Omidyar Houston Golf Association James Stern John R. Frank Larry R. Palmer, CEP, CTP Roy W. Howard Sternlicht Family Foundation Jim Freer William J. Polvino, MD James Hudson Louis B. Susman Robert Fremont John and Laura Pomerantz Jim Beam Brands Co. Allan R. Tessler Jerry Friedman Portland Bolt and Manufacturing Joseph H. Kanter Foundation William H. Tilley Steven Friedman Post Advisory Group Matthew Kaplan Time Inc. Carlos Fuente, Jr. Anthony & Jeanne Pritzker Bruce E. Karatz Jeanette Trepp Paul R. Garcia Family Foundation John Kelley Trimaran Capital Partners Philip H. Geier, Jr. Royce G. Pulliam Melvyn N. Klein Clark Van Nostrand Stephen A. Geppi Alan Quasha David and Janet Kline Fund Alice Walton Givingcapital LLC Mark Quigley The Kobrand Foundation Cheng Ching Wang Goldentree Asset Management Richard E. Rainwater Fred Kolber Casey and Laura Wasserman Bruce Goldstein Ramblewood Country Club Timothy Koogle Jerry and Jane Weintraub Edward and Cheryl Gordon The Riggio Foundation Dewanto Kurniawan Gary and Nina Wexler Maureen V. Gorman Bill R. Roberts

24 Prostate Cancer Foundation 2006 Progress Report 25 Donors • continued

Bob Roberts Michael Becker Terry Diamond Madison and Susan Graves Richard and Barbara Rosenberg Mitch Becker Dietz & Watson Foundation George D. Grayson Stan and Patti Rosenfeld Allen J. Beeber Richard DiMeola George L. Graziadio Round Hill Country Club William J. Bell Don King Productions, Inc. Steven and Dorothea Green Andrew Ruotolo Eric L. Berg Donaldson, Lufkin & Jenrette Alan C. Greenberg Barry L. Rupp Jeff Berg Carl Doumani Gary and Sandra Grimes Alvin and Marilyn Rush Anthony Bergamo, Esq. Milton H. Dresner Charitable Foundation Julie Groshens Peter M. Sacerdote Foundation Elliott H. Berger David H. Dreyfuss Michael S. Gross David Sambol Daniel G. Bergstein Dunwoody Country Club Roger S. Haber The Mara and Ricky Sandler Foundation David Berkoski Alvin Dworman David and Leslie Hahn Richard and Margaret Santulli The Judy and Howard Berkowitz Foundation Eastdil Realty, Inc. Brian L. Halla Richard Schmeelk Allen J. Bernstein Charles Edelstein Clay W. Hamlin, III John H. Schnatter The Stanley & Joyce Black Stephen Einhorn James A. Harmon Irving Schneider Family Foundation Steve Eiseman Richard J. Harrington Michael and Paola Schulhof Joni Hirsch Blackman David F. Eisner Mel Harris Brett T. Setzer Harvey Blau Roger A. Enrico William B. Harrison, Jr. David and Fela Shapell Charles X. Block Mike Ensign Richard C. Hartnack William Shaw Dennis Block The Daniel J. Epstein Fund of the Albert and Irene Hartog Mace and Jan Siegel Bloomberg Financial Markets Commodities News Jewish Community Foundation Richard J. Heckmann David and Lynn Silfen Burton Borman Jeff Epstein Andrew L. Heiskell Fred L. Smith Albert R. Boscov Evergreen Foundation Bruce Heller Irwin and Lorri Spiegel G. Michael Boswell Jonathan D. Farkas Jane Heller Fred and Sharon Stein Reggie Bowerman Federated Department Stores Foundation Jerry Hennessy Steinberg Family Fund, Inc. Steve Braverman Brad Felenstein Lawrence Herbert Spencer Stokes Bernard and Judy Briskin Robert M. Fell Sam Herzberg Burt and Mary Sugarman Brooklyn Hospital Center James and Alise Ferency Leon and Norma Hess Jim Tarlton Harry J. Brown Foundation Mike Ferry Andrew R. Heyer Mr. and Mrs. W. Thompson Bryanston Group, Inc. The Diane and Elliot Feuerstein Fund Rick Hill James Tisch Kurt W. Butenhoff of the Jewish Community Foundation The Armin & Esther Hirsch Foundation Marc Utay Bernie F. Butler Mark Finerman Douglas Hirsch and Holly Ander Peter Vegso Michael Butler Gerald B. Finneran HLT Prostate Cancer Fund Michael and Laura Venerable Canyon Partners Jerome and Anne Fisher H. S. Hoffman Linda J. Wachner Cardean Learning Larry and Kathleen Fisher Beth Hollfelder Charles J. Wagner Michael Caridi Lester and Gwen Fisher Butch Holmes Samuel Waksal Liam Carlos Richard Fisher Jane Holzer Ira Walker Johnny Carson Joseph Flom Homayoun Homampour Mr. and Mrs. Jay L. Wallberg Donald and Nancy Carter Florida Marlins Home Box Office Stephen and Maura Walsh Edwin P. Carter Steven T. Florio Steven and Cathy Hooper Michael and Jill Weinstein Marx L. Cazenave II Lynn Forester D. E. Brice Howe Stephen and Phyllis West Cell Genesys, Inc. Michael G. Foster, Jr. Helmut Huber Christopher and Kristine Williams Irwin Chafetz Foxsports.com Gene Humphrey H. L. Williams Linda Chen Lionel Frais Michael Hyatt Rick Wooley Peter Chernin Fred C. Hutchinson Cancer Research Center Royce Imhoff Don Zacharia Chubb Federal Insurance Company Paul Fribourg International Financiers, Inc. Citigroup Joshua S. and Beth Friedman Family Fund Invemed Associates LLC Supporters The Clark Charitable Foundation Stephen Friedman Ironman Motivations Coca-Cola Co. Larry H. Friend Jacks Broken Open ($10,000 - $24,999) Anonymous (2) Harold K. Cohen Peter Fudge Herb W. Jacobs David and Kay Aaker Mitchell H. Cohen Jeffrey Furman Sheldon Jacobs Paul Abecassis Jim and Marcia Colbert Frederick and Peggy Furth Ron Jacoby S. Daniel Abraham Commerce Bank, North, N.A. Ronald H. Galowich Mr. and Mrs. Robert M. Jaffe Abramson Family Foundation, Inc. Jimmy and Patti Connors Michael and Lynn Garvey Leonard R. Jaskol Joseph P. Adams, Jr. Nancy and James Cook General Nutrition Centers The JCT Foundation Sheldon Adelson David and Courtney Corleto Arie Genger Christopher M. Jeffries Larry Alleto The David and Sheila Cornstein Foundation Charles and Vivian Gillespie Michael and Linda Jesselson Bruce and Elvin Ambler Jack B. Corwin The Honorable Rudolph W. Giuliani Clark A. Johnson Lee W. Ang Ken Cory Guilford and Diane Glazer Allen N. Jones Judd Apatow Robert H. Cosgriff Alan and Marlene Gleicher Ellis B. Jones Michael F. Armstrong Terry Cosgrove Seth Glickenhaus The Joseph and Ida Foundation Inc. Michael F. Ashby Country Club of Roswell Colin Goddard, PhD Mitch Julis Atlanta Braves Foundation, Inc. Credit Suisse First Boston Corporation Bradley and Sunny Goldberg John Kahrhoff Memorial Golf Tournament Mark and Debbie Attanasio Alberto Cribiore Michael A. Goldberg Harold Sanford Kant, Esq. Jerry Auerbach Cuba Club Andy Goldfarb Scott G. Kasen Autism Speaks, Inc. Chip Cushman R. Anthony Goldman Peter M. Kash Abraham Azoulay Theodore Cutler Russell D. Goldsmith Howard and Susan Kaskel Dan Baldwin Cytogen Corporation Eric Goldstein David and Silvana Kay Martin and Dorothy Bandier Dabney/Resnick Imperial Michael Goldstein Joshua and Joia Kazam Jeffrey C. and Lori Barbakow John Daly The Golfworks Dean C. Kehler Sol Barer Len and Barbara Darling Family Fund Litto Gomez Gregory F. Kiernan F. Harlan Batrus J. Morton Davis Bennett Goodman Brian King William P. Beatson, Jr. Marvin and Barbara Davis The John R. & Kiendl Dauphinot Gordon Fund Michael G. King, Jr. Richard I. Beattie Roger J. Davis Berry Gordy, Jr. Kirkland & Ellis Foundation Warren Beatty and Annette Benning Michel De Beaumont Abraham D. Gosman Joel Kirschbaum Becker Family Fund of the Joseph J. Dempsey Fredric Gould Daniel J. Kleiman Baltimore Community Foundation Donald J. Deutsch Laurence Graff Calvin Klein Gary S. Becker Deutsche Bank Mark Grant Michael and Patricia Klowden

26 Prostate Cancer Foundation 2006 Progress Report 27 Harold and Shirley Kobliner Rooney Nelson Ian Schrager Robert Toll Jeff Koffman New England Financial The Schulhof Family Foundation Joe and Alice Torre KPMG, LLC Wayne and Kathleen Newton Schultz Family Foundation Richard P. Torykian, Sr. A. B. Krongard NFL Charities Marvin H. Schur Jesse I. Treu Mark Kurland Perry Nisen, MD, PhD Charles and Helen Schwab Prabhakar Tripuraneni, MD, FACR Herbert and Edyth Kurz Northern California District Alan D. Schwartz The Trump Organization Lachman Family Foundation Council of Laborers Ted Schwartz Tudor Investment Corporation Jeffery & Nancy Lane Foundation, Inc. Novacea, Inc. Schwartz, Kales Accountancy Corp. Valquip Corporation Latham & Watkins Marlene Nusbaum Charles “Red” Scott Karen van Nouhuys Leonard and Evelyn Lauder Oakland Athletics Russell Scott, Jr. Mary T. Venable William P. Lauder Cindy K. Olson Tony Scotti The Vons Companies Charitable Foundation, Inc. Steve Lawrence and Eydie Gorme Peter Busch Orthwein Sebastiani Vineyards, Inc. Rosemary Vrablic Norman Lear Gregory J. and Mary V. Pacelli Security Life Inc. Group Don Vultaggio Lederman Family Foundation Chuck Palombini Henry Seiden Shirlene A. Wainer Don and Rita Lee Marvin Parsons Ivan G. Seidenberg William and Claudia Walters Laurence C. Leeds, Jr. Alan Patricof Martin Selig Charlene Wang Richard S. LeFrak Norman J. Pattiz Mike Shad Kenneth Wang Stephen R. Leibowitz Paul, Weiss, Rifkind, Wharton & Garrison, LLP Michael Shapiro William and Sharon Ward Alfred and Norma Lerner David Pecker Shearman & Sterling Tom Watkins Julius and Miriam Lesner Clay and Elsie Pecorin Howard Shecter Scott Watt Frederick N. Levinger Gerry Pencer Mark Shenkman Robert F. Weis Frances and Jack Levy Foundation Arthur Penn Robert D. Shipp Melvyn I. Weiss John S. Levy Pensions 2000 Boaz Shonfeld Morris Weissman Richard Levy Leonard C. Perham Walter Shorenstein Dr. Herbert A. Wertheim Loida N. Lewis Phillips-Van Heusen Foundation, Inc. Stan Shuster Whittemore Family Foundation Robert Lienau Phoenix Home Life Mutual Stanley J. Sidel Ralph and Wendy Whitworth Mrs. Arthur Liman Insurance Company Sidney Frank Importing Company, Inc. Arthur Wiener Steven Lipman Albert and Jeanine Pirro Sanford C. Sigoloff Henry Wilf Michael D. London Michael A. Pitino Eugene Silverman Andrew Wise David B. Lowry Mack Pogue Jay B. Silverman Alexander J. Witherill Rufus and Patricia Lumry Carl and Eloise Pohlad Family Foundation Thomas M. Simms Fred Wolf Robert G. Lusk Steve Posner Mark J. Simon Douglas J. Wood Jerome D. Mack Maury Povich and Connie Chung Ted Simpkins C. Tal Wooten, Jr. Richard Mack Michael J. Price Sirens Society Young Presidents Organization, Macy’s Wayne Prim, Jr. Sanford Sirulnick Los Angeles Chapter John Magliocco Jay Pritzker John C. Sites Gerard Yvernault Peter A. Magowan Prometheus International, Inc. Charles B. Slack Louis G. Zachary, Jr. Mandalay Resort Group Ed W. Rabin Alan B. Slifka Harriet Zaretsky Alan and Barbara Mandelbaum Sheri and Marc Rapaport Fund Lynn Smiledge Jeffrey Dunston Zients Mandelbaum Foundation Bruce Ratner John F. Smith, Jr. Roy Zuckerberg Stuart Manheim, CPA Michael Ratner Matthew and Tracy Smith Robert A. Zummo Mel Mannion Randolph and Lindsey Read Orin Smith Stephen J. Marcus John S. Reed Snyder Weiner Weltchek & Vogelstein Contributors Mariners Care The Republic of Tea Marilyn Sobel ($5,000 - $9,999) Howard and Stacy Marks W. Brent and Brenda Rice Bruce Sokoloff Anonymous (2) Maverick Capital Foundation Denise Rich Bob Solomon Robert J. Abt Kenneth Mazik Robin Richards Warren J. Spector The Adler Family Foundation, Inc. Larry Mazzola James S. Riepe Family Foundation Allison Speer Advance Shared Services Center Michael and Kristy McChesney Richard A. Rigg Aaron and Candy Spelling AIM Management Group Les G. McCraw, Jr. Harold W. Ripps Jerry Speyer Alvin R. Albe John and Constance McGillicuddy Brian L. Roberts Lawrence Spira, MD Ellis J. Alden Thomas J. McKearn Kenn Roberts Joseph Stein R. Jack and Beulah Alexander Kara McKinley Ralph J. Roberts Jeffrey Steiner Donald and June Alford J. P. McManus Thomas and Mary Alice Roberts Irving Stenn, Jr. Lawrence B. Alletto James A. McRae James D. Robinson, III Karl Sternbaum Allied Beverage Group, LLC Medco Containment Co. Rodney Strong Vineyards Michael Strauss Arthur G. Altschul, Jr. Keith Meister Gerald Ronson Stricklin Account of Fidelity Charitable Gift Fund Ellsworth C. Alvord III Todd Meister Allison Rosen Lawrence Sheldon Stroll Richard W. Alvord Prakash Melwani Fredric D. Rosen Melanie Sturm Ameripoint Foundation Arnon Milchan Paul and Catherine Rosenberger Marianne Sufrin John Angelo Lee S. Millstein Betsy Ross Sanford and Charna Sugar Tom Armstrong Larry A. Mizel Byron Roth Sunbelt Beverage Company, LLC Phillip Asherian Robert Michael Mondavi James Rothstein Katharyn Swintek Michael Ashkin Charles K. Monfort Michel Roux Tag Associates, LLC Sherrell Aston Eugene Monkarsh James Russell Roberta R. Tanenbaum Victor K. Atkins David Moore Kenneth and Dina Russell Jeremiah and Nonie Tarr Aureon Laboratories, Inc. Pete Moore Edward B. Rust, Jr. Fredricka Taubitz Rick G. Avare Jerry Moss Donna Karan and Stephen Ruzow Ian Ross Taylor Bacardi Limited Wayne Mueller Ronald Saks Robert Taylor Jeffrey and Pamela Balton Donald R. Mullen Steve Sanak Douglas P. Teitelbaum Scott P. Barasch Peter Mullin Raymond and Helen Sandler Anthony Terlato Alexander E. Barkas and Lynda Wijcik Bill Mundell Richard Sandor Charles and Adele Thurnher Janice Barney Mr. and Mrs. Warren V. Musser Michael Sandorffy Andrew H. and Ann Tisch The Barrack Foundation Naples Drive for the Cure Sylvan Schefler Daniel and Bonnie Tisch Tyler Barth The Nash Family Foundation Andrew Scheinman Steven H. Tishman Michael J. Batza, Jr. Menasche M. Nass David Schneider Dennis A. Tito Charles T. Bauer David Nazarian Raymond D. Schoenbaum John T. Toland Ted Baum Marty Nealon Lewis M. Schott Bruce E. and Robbi S. Toll Foundation Lee Beattie

26 Prostate Cancer Foundation 2006 Progress Report 27 Donors • continued

Jack M. Beaven Cushman & Wakefield Blair Haarlow Laborers’ International Union - Bradley Bell Marion J. Davis, Jr. William and Evangeline Haarlow El Monte Local 1082 John Bendheim Ed DeBartolo, Jr. Lynn M. Haff Laborers’ International Union, Local 270 Walt L. Bent Paul R. Del Rossi Kerry and Kelly Hagen Laborers’ International Union Lee and Susan Benton Delaware North Companies, Inc. John Hagestad of North America - Local 300 Mr. and Mrs. Philip J. Bergan Delcal Enterprises, Inc. Hall Dickler Kent Goldstein & Wood, LLP LA-CO Industries, Inc. Martin S. Berger Jerry Della Femina Jesse Halperin Fred S. Lafer Leonard H. Bernheim, Jr. Robert Dodson Fred Hameetman Robert F. Lampe, Jr. Anthony J. Bettencourt Drexel University Mark S. Handler Ken Langone William C. Bevins Daniel A. Duc Mark S. Hanson Ira N. Langsan & Lillian Langsan Mr. and Mrs. Fred B. Bialek Duch Family Fund of the Martin Aaron Harmon Philanthropic Fund Les Bider Community Foundation Gilbert W. Harrison Robert Larner, MD Marc Blackman Raymond Duncan Lauren M. Hartman Martin and Sheila Lasky Robert S. Blank Joseph J. Dvorak, Jr. Kenneth and Kathryn Henderson Ronald Lauder Michael and Nina Blechman J. C. Earle Family Fund Thomas S. Henderson and Sally S. Lynn M. Leany Tim Blixseth Walter Eberstadt Henderson Foundation Frank Leanza James A. Block Spencer F. Eccles Arthur Hershaft Ken Leese Bloomberg L.P. David B. Edelson Michael B. Hershey Charles E. Leonard, III Ron Boeddeker Maurits E. Edersheim Edward and Gaye Hewson Steve Leonard Salvatore and Alison Bommarito Anders B. Eklov David Hicks Warner LeRoy Franklin Otis Booth, Jr. Elmwood Country Club Roderick Hills Margaret Lesher Kurt T. Borowsky Endocare, Inc. Leslie Wohlhan Himmel John and Betty Levin Richard Boughner Mr. and Mrs. Engelberg Peter A. Hochfelder Neil Levine Larry Bowman Robert Englander Robert W. Hoke Dan and Stacey Levitan Thomas S. Bowman Yan Erlikh Richard Scott Hollander David Levy Leonard Boxer Aaron R. Eshman Vincent Horcasitas Edward Lewis Thomas Breitling Linda Evangelista Gerald Horowitz The Liberal Do-Gooder Foundation Stephen M. Brett William F. Evans John and Sandra Horvitz David Liebowitz Pete Briger Samer Farah, MD Thomas J. Howa Sio Lindner Pam Brill Andrew Farkas Joe Howe Samuel S. Lionel Nancy Brinker Michael S. Fawer Mark Hughes Jeffrey and Susan Liss Gary Briskman Dr. Jeffrey Feingold The Litwin Foundation, Inc. Wayne Huizenga Edward Brodsky Stanley M. Feingold The Loa Productions, Inc. James Husband Mr. and Mrs. Jeffrey P. Brown Irving Feintech The Arthur Loeb Foundation George Hutchinson Richard A. Brown Frank and Victoria Fertitta John L. Loeb, Jr. Institute for Health & Christopher H. Browne Gregory Fischbach Shumer Lonoff Productivity Management Richard C. Browne Richard B. Fisher Bob Lorsch Hale S. Irwin Gloria S. Browning Stephen B. Fiverson Douglas and Nancy Lowe The J.P. Morgan Chase Foundation Marc R. Brutten Karen A. Flann and Homer Schwartz Lyncar Enterprises, Inc. Jeremy Jacobs Deborah L. Burger, Inc. Dennis Flatt Harry Macklowe Nathan P. Jacobs Alan A. Burgess Robert Forbes John Magnier Max Javit Jack Burstein Sam Forman Anthony J. Magro Gordon W. Jenkins Richard Byrd Gayle Devers Fortune Brian A. Maki Charles Jennings Phil Caputo David Foster Idelisse Malave Jewish Federation of Greater Phoenix Ronald G. Carley Michael Frankel Judd Malkin William M. Carson Albert Fried, Jr. JFD / MJD Golf Open Shareef Malnik Frank L. Cassidy, Jr. Joel Friedland James and Lorene Jimmerson George J. Maloof Matthew J. Celozzi II, PhD Robert and Ann Fromer Alastair J. Johnston Bernard A. Marden Clive and Bonnie Chajet Roy Furman Kaiser Permanente Morris Mark Michael J. Charles Tom W. Gamel Jay Kaiser Ken Martin Sophie Chen, PhD Howard Ganek Thomas J. Kalinske Kim Martindale Bernd Chorengel Lloyd Garver Bruce and Jeanie Kaminsky Elliott Masie Allen and Jill Chozen Lucio and Marta Gasperina The Kandell Fund Norman and Joanne Matthews Clarium Capital Management, LLC Frank Gehry Walter Karabian Giacomo Mattoli Greg Clark Alan Gelband Stanley Katz Caryn Mautner John H. Claster Genentech, Inc. Stephen Katz Thomas and Musa Mayer Bert Cohen Georgetown Tobacco & Pipe Stores, Inc. George Kaufman Marilyn McCoo and Billy Davis Joseph M. Cohen S. William Gersten Ivan Kaufman Richard E. McCready Foundation Fund of Richard D. Cohen Michael F. Gilligan, Jr. Ronald S. Kaufman the Baltimore Community Foundation The Betsy and Alan Cohn Foundation, Inc. Tom Giovanelli Ilan and Linda Kaufthal Liam E. McGee Victor A. Cohn David H. Glaser Richard and Suzanne Kayne John S. McIlwain William S. Comanor, PhD Arthur M. Goldberg Gershon Kekst Laureston and Barbara McLellan Michelle A. Connelly Howard Goldenson Donald H. Keltner Don McNamara James C. Cook Steve A. Goldfarb Ken Roberts Company Robert J. McNulty Elaine Terner Cooper Dr. Kenneth N. Goldman Keys Foundation Rolf Meijer-Werner John Cooper, Jr. Bradford S. Goodwin Kibble & Prentice Merrill Lynch & Company Foundation, Inc. Stephen A. Cooper, DMD, PhD Richard Goodwin Kidz, LLC Merritt Management Corp. Peter Coors Todd Goodwin Lila Kingsley The Morris and Helen Messing Foundation The Copses Family Foundation Jerome S. Gore James W. Klein David A. Miller Fred Corrado John P. Gould Burton Koffman Laura and Michael Miller Marshall B. Coyne Mr. and Mrs. Louis J. Grasmick Eugene Kohn Honorable Robert Joseph Miller Cresa Partners Jim Grau Oswaldo Kosta Peter H. Mills Richard Crisman Charles H. Greenberg Roger and Lorraiine Kotch Phillip S. Mittelman Robert and Mary Ann Cross Mark Greenhill Robert Kraft Alan Mnuchin Gregory Cuneo Robert Grossman Jules B. Kroll Arthur and Patricia Modell Cunningham Security Systems Howard R. Gurvitch Norman D. Kurtz James J. Moglia

28 Prostate Cancer Foundation 2006 Progress Report 29 PLAYER Medical Industry NO. 85 - Total number of pharmaceutical, biotechnology and device partners Partnering with the medical industry enables the Prostate Cancer Foundation to play an important role not only in the early discovery of innovative research ideas but also in the development of new therapeutics that can help men with prostate cancer live longer and better lives.

The Prostate Cancer Foundation acknowledges the following biopharmaceutical companies that supported our work in 2006.

Donors • continued David Moore Rick Powell Robert Schulman Rica F. Tarnoff Raymond Moore Ed Prager Gerald M. Schuster Janie C. Tarter Morongo Band of Mission Indians Arlen I. Prentice Governor Arnold Schwarzenegger Stanley G. Tate William S. Morris, III William L. Price and Mrs. Maria Shriver Walter D. Tearse Morton’s Restaurant Group Wayne Prim, Sr. Lisa White Schweitzer Vincent Tese Judy Bardugo and Harve H. Mossawir, Jr. Edward Probyn Peter W. Schweitzer Chuck B. Thornton, Jr. Paul Motenko Bob Pryt Spencer and Jacqueline Segura The Laura Steinberg Tisch Foundation, Inc. Charles H. Mott John A. Ptak Dr. Michael E. Seiff Tom Tisch Joseph M. Murphy Kjell H. Qvale Richard M. Seigel TJH Alan C. Myers Mark Rachesky David M. Shaffer Stanley S. Trotman, Jr. Douglas P. Nation Robert E. Racicot Michael S. Shannon Cecily Truett Lee S. Neibart Steve Rader Thomas J. Shannon, Jr. Mark Truitt Craig T. Nelson Harvey and Pauline Radler Carl and Ruth Shapiro Family Foundation Jeffrey H. Tucker Mary-Rose Nelson Raley’s Gold Rush Classic Robert F. Shapiro Turner Broadcasting System, Inc. Nestlé Waters North America, Inc. Max Ramberg Thomas and Medeleine Sherak Alfred Tyler II Blake Lee Neubauer, PhD Donald Rechler Pam Shriver Fund of the UBS AG Shilom Neuman Scott Gregg Rechler Baltimore Community Foundation Peter V. Ueberroth Chuck Nicolette, MD Blair & Kristin Richardson Foundation Herbert J. Siegel William D. Unger Niebaum-Coppola Estate Winery Joseph P. Riccardo William Siegel United Jewish Foundation of James B. Nish Ritz-Carlton Adrianne W. Silver Metropolitan Detroit Douglas and Nancy Norberg Ritz-Carlton Boston Richard Silverman Tom Unterman Greg Norman Lee P. Rizzuto Ronald A. Simms Michael J. Urfirer Nsuh Foundation Linda G. Robinson David Simon Neil G. Van Luven Obermeyer Asset Management Company Sam Robson Dick Simon Basil K. Vasiliou James T. O’Brien Iber Rodriguez Mimi Simoneaux The Daniel Veloric Foundation Morris Offit Sig Rogich James D. Sinegal Velos Medical Informatics, Inc. John O’Hurley Jeffrey Rosenthal Van Skilling Mary E. Venable Marvin Olshan Stephen M. Ross Joel E. Smilow Benjamin Wade Shepard Osherow Gordon Roth Gordon Smith Robert and Judy Waller Dan Otter Edward F. Rover Jeff N. Smith David E. Walters Corbin Page, Estate of Donald P. Pakosh Amy and Richard Ruben Arnold Snider John Walton Norm Pappas Mariano A. Rubino Steve Snyder Jack L. Warner Donald J. Parmet The Rachel and Lewis Rudin James Soules Roger Weber Partners Marketing Group Family Foundation, Inc. Southern Company Services, Inc. Raymond J. Weis Rafael Pastor Denny Ryerson Larry Spitcaufsky Robert Weiss E.H. Patterson Thomas L. Safran Richard and Ellie Sprague Jay Weitzman Randall Eric Paulson Max Salter Frank P. Stagen Miles D. White David R. Pedowitz Allan C. Sanders Starbucks Coffee Company Jeffrey S. Wilks James C. Pendergast Theodore and Alison Sands John Stark Gary L. Wilson Mark Perlbinder Sandy Spring Bank Steven E. Stern Daniel P. Wimsatt Charles Persico Patrick Savin The Stone Family Fund Moira Wolofsky James L. Peters Saybrook Tax-Exempt Advisors, LLC Bonnie and Tom Strauss Rodney A. Wray Robert E. Petersen Al Scheid Chris Stuhmer Bud Yorkin Pharmaceutical Research and Schmertz Company, Inc. Mary M. Sullivan Young Presidents Organization Manufacturers of America Alfons J. Schmitt Dennis A. Suskind Rebel Chapter Gerald Porter David M. Schoenthal Don Swirnow Stan Zicklin Timothy N. Poster Marvin I. Schotland S. Jerome and Judith Tamkin Ron Zimmerman

28 Prostate Cancer Foundation 2006 Progress Report 29 PLAYER Universities NO. 150 - Total number of Competitive Award and Therapy Consortium institutions The Prostate Cancer Foundation has played an important role in helping to establish and support nearly 150 robust prostate cancer research programs at institutions in the United States and worldwide – nearly 10 times the number of programs in place when the PCF was founded in 1993. Research Awards

The Prostate Cancer Foundationʼs Competitive Awards Program supports innovative, early-stage prostate cancer research projects. The following institutions and researchers have received funds from this program. Lewis C. Cantley, PhD Huatao Guo, PhD Albert Einstein Cold Spring Harbor Laboratory College of Medicine Mark A. Exley, MSC, PhD Alexander J. Varshavsky, PhD $100,000 $75,000 John V. Fragioni, MD, PhD Robert Lucito, PhD Nicole B. Schreiber-Agus, PhD Sandra M. Gaston, PhD California Pacific Xuesong Gu, PhD Medical Center Columbia University Assaf Harofe Medical Richard Junghans, MD, PhD $100,000 $2,229,500 Center (Israel) Towia A. Libermann, PhD Robert J. Debs, MD $100,000 Allen Pavilion Massimo Loda, MD Presbyterian Hospital Amnon Zisman, MD Carl A. Olsson, MD Jan E. Schnitzer, MD Cancer Institute of New Jersey $75,000 Bar-Ilan University (Israel) Atchley Pavilion $225,000 Brandeis University Robert S. DiPaola, MD Ralph Buttyan, PhD $250,000 Shlomo Grossman, PhD Lizbeth Hedstrom, PhD Uri Nir, PhD Cantonal Hospital St. Gall College of Physicians Gregory A. Petsko, PhD and Surgeons (Switzerland) Paul B. Fisher, PhD $75,000 Baylor University Aaron E. Katz, MD $3,855,000 Brigham and Womenʼs Hospital Marcus Groettrup, PhD $690,000 Nickolas Papadopoulos, PhD Jacques Banchereau, PhD Anthony V. D’Amico, MD, PhD Case Western Reserve University Columbia Presbyterian Baylor College of Medicine Francesca Demichelis, MSC, PhD $350,000 Norman M. Greenberg, PhD Phillip G. Febbo, MD Medical Center Sanford Markowitz, MD, PhD Edward P. Gelmann, MD Naijie Jing, PhD James W. Fett, PhD Bingcheng Wang, PhD Daniel Petrylak, MD Dov Kadmon, MD Joshua LaBaer, MD, PhD Paula Kaplan-Lefko, PhD Kevin R. Loughlin, MD Cornell University Michael Kattan, PhD Jing Ma, MD, PhD Cedars-Sinai Medical Center $4,199,325 $3,556,640 Dolores J. Lamb, PhD Karen A. Olson, PhD Beatrice S. Knudsen, MD, PhD David B. Agus, MD Bert W. O’Malley, MD Jeffrey L. Sklar, MD, PhD David M. Nanus, MD David R. Rowley, PhD H. Phillip Koeffler, MD Isett Laux, PhD New York Peter T. Scardino, MD British Columbia Presbyterian Hospital Timothy C. Thompson, PhD Cancer Agency Neil H. Bander, MD $100,000 Ming-Jer Tsai, PhD Childrenʼs Hospital Boston Ashutosh K. Tewari, MD, MCH Nancy L. Weigel, PhD Yuzhuo Wang, PhD $900,000 Ming Zhang, PhD Judah Folkman, MD Dana-Farber Cancer Institute Burnham Institute Michael Klagsburn, PhD $1,888,666 $6,085,000 Ben-Gurion University of the Calvin J. Kuo, MD Wadih Arap, MD, PhD Ranaan Berger, MD, PhD Negev (Israel) Marsha A. Moses, PhD Myles A. Brown, MD $325,000 Nuria E. Assa-Munt, PhD Richard C. Mulligan, PhD Harvey Cantor, MD Ron N. Apte, PhD Kathryn R. Ely, PhD Bruce R. Zetter, PhD Diego Castrillon, MD, PhD Joseph Levy, PhD John C. Reed, MD, PhD Angel Porgador, PhD Erkki I. Ruoslahti, MD, PhD Lan Bo Chen, PhD Shraga Segal, PhD Cleveland Clinic Foundation Ronald A. DePinho, MD $250,000 Glenn Dranoff, MD California Institute Katerina Gurova, PhD Phillip G. Febbo, MD Beth Israel of Technology Edward Plow, PhD Deaconess Medical Center $450,000 Levi A. Garraway, MD, PhD $560,000 Raymond J. Deshaies, PhD Robert H. Silverman, PhD Daniel J. George, MD

Awardees were performing research at the listed institution at the time funds were granted.

30 Prostate Cancer Foundation 2006 Progress Report 31 William C. Hahn, MD, PhD William G. Nelson, MD, PhD James P. Allison, PhD Harvard University Philip W. Kantoff, MD $250,000 Alan W. Partin, MD, PhD William R. Fair, MD David M. Livingston, MD James W. Fett, PhD Roberto Pili, MD George Farmer, PhD Massimo Loda, MD Ronald Rodriguez, MD, PhD Leonard P. Freedman, PhD Thomas Roberts, PhD Harvard Medical School Jonathan W. Simons, MD Zvi Fuks, MD William R. Sellers, MD $2,050,000 Dan Stoianovici, PhD Bernd Gansbacher, MD Myles A. Brown, MD Sabina Signoretti, MD Patrick C. Walsh, MD Polly Gregor, PhD Lan Bo Chen, PhD Bruce M. Spiegelman, PhD Srinivasan Yegnasubramanian, MD, PhD Adriana Haimovitz-Friedman, PhD Michael Klagsbrun, PhD Robert H. Vonderheide, MD, DPhil Warren D.W. Heston, PhD David M. Livingston, MD Karolinska Institute (Sweden) William Kevin Kelly, DO Massimo Loda, MD $75,000 Philip O. Livingston, MD Dartmouth-Hitchcock Marsha A. Moses, PhD Hans-Olov Adami, MD, PhD Medical Center Richard C. Mulligan, PhD Paul A. Marks, MD $75,000 Michael R. McDevitt, PhD Jane E. Schnitzer, MD Klinikum de Justus-Liebig Marc S. Ernstoff, MD David M. Nanus, MD Jeffrey L. Sklar, MD, PhD Universitat Giessen (Germany) Bruce M. Spiegelman, PhD $200,000 Neal Rosen, MD, PhD Duke University Trinad Chakraborty Michael Sadelain, MD, PhD $1,100,000 Bruce R. Zetter, PhD Peter T. Scardino, MD Phillip G. Febbo, MD Anthony L. Zietman, MD La Jolla Institute for Allergy David A. Scheinberg, MD, PhD Daniel J. George, MD and Immunology Howard I. Scher, MD Eli Gilboa, PhD Harvard School of Public Health $75,000 $725,000 George Sgouros, PhD Susan Halabi, PhD Stephen Schoenberger, PhD June M. Chan, ScD David Shaffer, MD, PhD Michael C. Pirrung, PhD Edward Giovannucci, MD Moshe Shike, MD David T. Price, MD Long Island College Hospital Laurie H. Glimcher, MD Susan F. Slovin, MD, PhD Johannes W. Vieweg, MD $15,000 Meir Stampfer, MD, ScD Ivan Grunberger, MD Peter Smith-Jones, PhD Dimitrios Trichopoulos, MD David B. Solit, MD Earle A. Chiles Sven Wenske, MD Research Institute Loyola University $100,000 Hebrew University (Israel) Medical Center Jedd D. Wolchok, MD, PhD $1,200,000 $200,000 Bernard A. Fox, PhD Yinon Ben-Neriah, MD, PhD Eugene D. Kwon, MD Howard Cedar, MD, PhD Menzies Centre for Population Eastern Virginia Medical School Eli Keshet, PhD Health Research (Australia) $175,000 McGill University $50,000 Alexander Levitzki, PhD $163,000 George L. Wright, Jr., PhD David A. Mackey, MD David Naor, PhD Nahum Sonenberg, PhD

Emory University Jewish General Hospital Mount Sinai School of Medicine $250,000 Henry M. Jackson Foundation Michael N. Pollak, MD $375,000 $99,978 Wayne Harris, MD Albert Dobi, PhD Michael J. Droller, MD John A. Petros, MD Massachusetts General Hospital Irwin H. Gelman, PhD $750,000 John A. Martignetti, MD, PhD Jonathan W. Simons, MD Indiana University $300,000 Joel Finkelstein, MD Robert L. Martuza, MD Erasmus University (Netherlands) Thomas A. Gardner, MD New York Medical College $250,000 Jian-Ting Zhang, PhD Matthew R. Smith, MD, PhD $150,000 Jan Trapman, PhD George W. Sledge, MD Ching-Hsuan Tung, PhD Cancer Research Institute Gert J. van Steenbrugge, PhD Anthony L. Zietman, MD Sophie Chen, PhD Institute for Systems Biology $500,000 Massachusetts Institute of Fred C. Hutchinson Cancer New York University Leroy E. Hood, MD, PhD Technology Research Center $1,535,000 $430,000 $2,753,914 Sandra M. Gaston, PhD Maarten C. Bosland, DVSc, PhD Peter S. Nelson, MD John Wayne Cancer Institute Herbert Lepor, MD $50,000 Richard O. Hynes, PhD Elaine A. Ostrander, PhD Frederick R. Singer, MD Jun O. Liu, PhD Ian J. Mohr, PhD Janet L. Stanford, PhD Peter H. Seeberger, PhD Samir Taneja, MD Johns Hopkins University Ganesh Venkataraman, PhD Georgetown University $15,871,867 Skirball Institute of $1,100,000 Biomolecular Medicine Philip A. Beachy, PhD Whitehead Institute for Ruben Abagyan, PhD Lombardi Cancer Center David Berman, MD, PhD Biomedical Research Edward P. Gelmann, MD G. Steven Bova, MD John M. Essigmann, PhD Northwest Hospital Robert L. Martuza, MD Michael A. Carducci, MD Eric S. Lander, PhD Richard C. Mulligan, PhD $475,000 Renxiao Wang, PhD Angelo DeMarzo, MD, PhD Gerald P. Murphy, MD, DSc Shaomeng Wang, PhD Samuel R. Denmeade, MD Mario Eisenberger, MD Mayo Clinic and Foundation $500,000 Northwestern University Stephen J. Freedland, MD Lorraine A. Fitzpatrick, MD $200,000 Hadassah University (Israel) Robert H. Getzenberg, PhD John C. Morris, MD Wade Bushman, MD, PhD $598,550 John T. Isaacs, PhD Donald J. Tindall, PhD Zhou Wang, PhD Rachel Bar-Shavit, PhD William B. Isaacs, PhD Eithan Galun, MD, PhD Clara L. Kielkopf, PhD Memorial Sloan-Kettering Ohio State University Amnon Peled, PhD $300,000 Hyam I. Levitsky, MD Cancer Center Eli Pikarsky, MD, PhD Jun O. Liu, PhD $18,903,272 Ching-Shih Chen, MD, PhD Israel Vlodavsky, PhD Joel B. Nelson, MD David B. Agus, MD M. Guill Wientjes, PhD

Awardees were performing research at the listed institution at the time funds were granted.

30 Prostate Cancer Foundation 2006 Progress Report 31 Research Awards • continued

Oregon Health Sciences State University of New York University of California System University of California, University $112,500 $20,064,476 San Francisco $100,000 $8,885,898 Downstate Medical School Jeffrey Arbeit, MD Ron G. Rosenfeld, MD Jack Mydlo, MD Lawrence Livermore National Laboratory Allan Balmain, PhD $75,000 Elizabeth Blackburn, PhD Preventive Medicine Stony Brook Christine Hartmann Siantar, PhD Robert H. Blelloch, MD, PhD Research Institute Victor I. Romanov, PhD $500,000 Robert A. Bok, MD, PhD Peter R. Carroll, MD Dean Ornish, MD University of California, Berkeley Technion, Israel Institute of $1,066,666 June M. Chan, ScD Technology (Israel) Colin Collins, PhD $950,000 James P. Allison, PhD Rabin Medical Center (Israel) Heike E. Daldrup-Link, MD, PhD $50,000 Ami Aronheim, PhD Carolyn Bertozzi, PhD Marc I. Diamond, MD Avishay Sella, MD Arthur A. Hurwitz, PhD Aaron Ciechanover, MD, DSc Robert J. Fletterick, PhD Fuad Fares, DSc David H. Raulet, PhD Mark W. Frohlich, MD Rockefeller University Ehud Keinan, PhD Peter G. Schultz, PhD $500,000 Rodney Guy, PhD Gera Neufeld, PhD David E. Wemmer, PhD Robert G. Roeder, PhD Douglas Hanahan, PhD Israel Vlodavsky, PhD Ronald H. Jensen, PhD Strang Cancer Research University of California, Davis John Kurhanewicz, PhD $269,572 Laboratory Tel-Aviv University (Israel) James D. Marks, MD, PhD Ralph W. de Vere White, MD Martin Lipkin, MD $400,000 Dean Ornish, MD Zvi Fishelson, PhD Christopher P. Evans, MD Timothy P. Quinn, MD Roger Williams Medical Center Sara Lavi, PhD Shing-Jien Kung, PhD Mack Roach, III, MD $225,000 Ada Rephaeli, PhD Eric J. Small, MD Richard P. Junghans, MD, PhD Ilan Tsarfaty, PhD University of California, Thea Tlsty, PhD Qiangzhong Ma, PhD Los Angeles Paul Webb, PhD Sourasky Medical Center $9,347,362 Ben-Zion Katz, PhD Salk Institute for Arie S. Belldegrun, MD University of California, Avi Orr-Urtreger, MD, PhD Santa Barbara Biological Studies Michael F. Carey, PhD $100,000 $760,500 Rowan T. Chlebowski, MD, PhD Dulal Panda, PhD Ronald M. Evans, PhD Thomas Jefferson University Pinchas Cohen, MD $125,000 Michael J. Mastrangelo, MD Jean B. deKernion, MD University of Chicago San Diego Cancer Research $492,900 $75,000 Albert J. Wong, MD Purnima Dubey, PhD Douglas K. Bishop, PhD R. Michael Williams, MD, PhD Sanjiv S. Gambhir, MD, PhD Carrie W. Rinker-Schaeffer, PhD Tulane University David Heber, MD, PhD Mitchell H. Sokoloff, MD Scripps Research Institute $500,000 Harvey R. Herschman, PhD $975,000 Andrew V. Schally, MD, PhD Ben May Institute for Michael E. Jung, PhD Cancer Research Ruben A. Abagyan, PhD Jay R. Lieberman, MD Shutsung Liao, PhD K.C. Nicolaou, PhD University Hospital, Nijmegen Carl W. Miller, PhD Prabhakar Tripuraneni, MD (Netherlands) University of Colorado $275,000 Ayyappan K. Rajasekaran, PhD $730,000 Marion J.G. Bussemakers, PhD Robert E. Reiter, MD L. Michael Glode, MD Sheba Medical Center (Israel) $150,000 Peter Rosen, MD William E. Huffer, MD Gideon Rechavi, MD, PhD University of Alabama, Kathleen M. Sakamoto, MD Andrew S. Kraft, MD Birmingham Charles L. Sawyers, MD Gary J. Miller, MD, PhD $200,000 Sidney Kimmel Cancer Center Ke Shuai, PhD $100,000 David T. Curiel, MD University of Connecticut Peter Tontonoz, MD, PhD Michael McClelland, PhD Richard D. Lopez, MD $147,603 Owen N. Witte, MD Linda H. Shapiro, PhD Hong Wu, MD, PhD Pramod Srivastava, PhD Skirball Institute of University of Arizona Biomedical Medicine $100,000 Lily Wu, MD, PhD $100,000 Leslie Gunatilaka, PhD University of Edinburgh Ruben A. Abagyan, PhD University of California, Riverside (Scotland) Mark W. Kunkel, PhD $100,000 $75,000 Ameae M. Walker, PhD Fouad K. Habib, PhD St. Louis University University of Basel $75,000 William S.M. Wold, PhD (Switzerland) University of California, University of Helsinki (Finland) $75,000 San Diego $200,000 Lukas Bubendorf, MD $1,500,000 Institute of Biomedicine Stanford University Dennis A. Carson, MD Olli A. Janne, MD, PhD $1,500,000 University of Bern (Switzerland) Randolph D. Christen, MD Gerald R. Crabtree, MD $100,000 Lawrence S.B. Goldstein, PhD University of Illinois David Feldman, MD George N. Thalmann, MD $150,000 Calvin J. Kuo, MD, PhD Michael Karin, PhD Nissum Hay, PhD Michael G. Rosenfeld, MD John E. McNeal, MD University of British Columbia Donna M. Peehl, PhD $200,000 Helen P. Tighe, PhD University of Illinois, Urbana-Champaign Thomas A. Stamey, MD Martin E. Gleave, MD Maurizio Zanetti, MD Jianjun Cheng, PhD

Awardees were performing research at the listed institution at the time funds were granted.

32 Prostate Cancer Foundation 2006 Progress Report 33 University of Innsbruck (Austria) University of Pittsburgh University of Toronto (Canada) Volcani Center (Israel) $103,000 $2,623,900 $350,000 $180,000 Mark Pines, PhD Zoran Culig, MD Michael J. Becich, MD, PhD Sunnybrook Health Science Center Barbara A. Foster, PhD Shoukat Dedhar, PhD University of Iowa John Gilbertson, MD Robert S. Kerbel, PhD Vrije Universiteit medisch $175,000 Susan L. Greenspan, MD centrum (Netherlands) $100,000 Michael D. Henry, PhD Candace S. Johnson, PhD University of Utah, Tanja D. de Gruijl, PhD George Weiner, MD Joel B. Nelson, MD Health Sciences Center Denise S. O’Keefe, PhD $100,000 Arthur R. Brothman, PhD Wake Forest University University of Kentucky Beth R. Pflug, PhD $65,000 $100,000 Uzma S. Shah, PhD Purnima Dubey, PhD Donald L. Trump, MD University of Virginia Vivek M. Rangnekar, PhD $4,150,000 Janey Whalen, PhD John M. Chirgwin, PhD Walter Reed Army Medical University of Louisville Leland W.K. Chung, PhD Center $100,000 $50,000 University of Regensburg Thomas A. Gardner, MD LaCreis R. Kidd, PhD, MPH (Germany) David G. McLeod, MD, JD $99,760 Theresa Guise, MD Deborah Lannigan, PhD Christoph A. Klein, MD Washington University University of Maryland Charles E. Myers, Jr., MD $300,000 $3,339,166 J. Thomas Parsons, PhD Natasha Kyprianou, PhD University of Rochester William J. Catalona, MD $500,000 Fraydoon Rastinejad, PhD Mark L. Day, PhD Yun Qiu, PhD Chawnshang Chang, PhD Mitchell H. Sokoloff, MD Helen Donis-Keller, PhD Edward Messing, MD Michael J. Weber, PhD Steven F. Dowdy, PhD University of Massachusetts Ganesh S. Palapattu, MD Peter A. Humphrey, MD, PhD $425,000 Jeffrey Milbrandt, MD, PhD Robert E. Carraway, PhD University of Washington University of Southern California $8,361,342 Nobuyuki Oyama, MD, PhD Michael R. Green, MD, PhD $589,282 Arthur Camerman, PhD Timothy L. Ratliff, PhD Shuk-Mei Ho, PhD Gerhard A. Coetzee, PhD Martin A. Cheever, MD Brian K. Suarez, PhD Mani Menon, MD Christopher A. Haiman, ScD Leroy E. Hood, MD, PhD Shi-Lung Lin, PhD Gail Jarvik, MD, PhD Wayne State University University of Michigan Donald G. Skinner, MD Paul H. Lange, MD $350,000 $4,624,935 Mariana C. Stern, PhD Alvin Liu, PhD Michael L. Cher, MD Arul M. Chinnaiyan, MD, PhD Robert L. Vessella, PhD Kenneth V. Honn, PhD Mark Day, PhD University of Tampere (Finland) $300,000 Harper Hospital Evan T. Keller, DVM., PhD University of Wisconsin J. Edson Pontes, MD Tapio Visakorpi, MD, PhD Donna Livant, PhD $4,164,580 David A. Boothman, PhD Robert D. Loberg, PhD Weizmann Institute of Science University of Tennessee Wade Bushman, MD, PhD Kenneth J. Pienta, MD (Israel) $150,000 Chawnshang Chang, PhD $1,949,650 Russell S. Taichman, DMD, DMSc Jeffrey Gingrich, MD David F. Jarrard, MD Avri Ben-Ze’ev, PhD Martin G. Sanda, MD Douglas G. McNeel, MD, PhD Hadassa Degani, PhD Shaomeng Wang, PhD University of Texas $14,728,213 George Wilding, MD Zelig Eshhar, PhD Donald T. Witiak, PhD Benjamin Geiger, PhD University of Minnesota Health Science Center at Yitzhak Koch, PhD $100,000 San Antonio Urological Sciences Yoram Salomon, PhD Junxuan Lu, PhD Susan Padalecki, PhD Research Foundation Rony Seger, PhD $100,000 MD Anderson Cancer Center Yechiel Shai, PhD University of Missouri Wadih Arap, MD, PhD Leonard S. Marks, MD Yosef Shaul, PhD $75,000 Danai Daliani, MD David Wallach, PhD Valeri V. Mossine, PhD John DiGiovanni, PhD Utah State Cancer Registry Yosef Yarden, PhD Isaiah J. Fidler, DVM., PhD $183,420 Yehiel Zick, PhD University of Nebraska Sue-Hwa Lin, PhD Janet Stanford, MD $100,000 Christopher J. Logothetis, MD Yale University Ming-Fong Lin, PhD David J. McConkey, PhD Vancouver General Hospital $300,000 $100,000 Craig M. Crews, PhD Timothy J. McDonnell, MD, PhD Martin E. Gleave, MD University of North Carolina, Nora M. Navone, MD, PhD Alan Garen, PhD Chapel Hill Christos N. Papandreou, MD, PhD $250,000 Vanderbilt University Renata Pasqualini, PhD $540,000 David Ornstein, MD Padmanee Sharma, MD, PhD Sam Chang, MD Terry Van Dyke, PhD Dean G. Tang, MD, PhD Jay H. Fowke, PhD, MPH Andrew C. von Eschenbach, MD Robert Matusik, PhD University of Pennsylvania Zhengxin Wang, PhD Joseph A. Smith, Jr., MD $400,000 Christopher G. Wood, MD Mark I. Greene, MD, PhD Veteranʼs Administration Southwestern Medical Center, $8,745 Wistar Institute Dallas George C. Prendergast, PhD Jerry W. Shay, PhD Patricia Cornett, MD

Awardees were performing research at the listed institution at the time funds were granted.

32 Prostate Cancer Foundation 2006 Progress Report 33 Therapy Consortium

The Prostate Cancer Foundationʼs Therapy Consortium supports clinical trial infrastructure at eight leading medical institutions. The following clinical investigators that comprise the Therapy Consortium are among the most respected prostate cancer researchers in the United States: Cedars-Sinai Medical Center The Johns Hopkins University, University of California, San Francisco Sidney Kimmel Cancer Center Comprehensive Cancer Center

David B. Agus, MD Research Director, Mario A. Eisenberger, MD Eric J. Small, MD Louis Warschaw Prostate R. Dale Hughes Professorship Professor of Medicine and Urology; Cancer Center in Oncology; Professor Director of Urologic Oncology Research of Urology Dana-Farber Cancer Institute University of Michigan Medical Center

Philip Kantoff, MD Michael A. Carducci, MD Kenneth J. Pienta, MD Director, The Lank Center for Genitourinary Associate Professor of Oncology and Professor of Internal Medicine and Urology; Oncology; Chief, Division of Solid Tumor Oncology Urology; Co-Director, Drug Co-Director of the Urologic/Prostate Development Program Oncology Research Program MD Anderson Cancer Center, University of Texas

William G. Nelson, MD, PhD Maha Hussain, MD Professor of Oncology, Urology, Professor of Internal Medicine Christopher J. Logothetis, MD Pharmacology, Medicine, Pathology and and Urology Chair and Professor, Genitourinary Radiation Oncology; Director, Molecular Medical Oncology Pharmacology Laboratory; Co-Director, University of Wisconsin Anti-Cancer Drug Discovery and Comprehensive Cancer Center Memorial Sloan-Kettering Development Program; and Co-Director, Cancer Center Genitourinary Oncology Program

George Wilding, MD Howard I. Scher, MD Director, Comprehensive Cancer Center; Chief, Genitourinary Oncology Service; Assistant Dean for Oncology; Anderson D. Wayne Calloway Chair in Urologic Oncology Professor of Medicine

34 Prostate Cancer Foundation 2006 Progress Report 35 PLAYER Prostate Cancer Foundation NO. 56NO. - 56Executive - Executive Leadership, Leadership, Board Board of Directors of Directors and Staffand Staff The dedication of the Prostate Cancer Foundation, its Board of Directors and its staff members has enabled hundreds of investigators aroundinvestigators the world around to workthe world tirelessly to work to findtirelessly better to treatments find better and treatments a cure for and recurrent a cure forprostate recurrent cancer. prostate cancer.

Presidential Board of Directors Leadership Team

Board Mike Milken Shmuel Meitar Jonathan W. Simons, MD Founder and Chairman Director Chief Executive Officer and President, Prostate Cancer Foundation Aurec Group David H. Koch Chair

Charles F. Baird, Jr. Leslie D. Michelson Ralph Finerman Managing Partner Chief Financial Officer, North Castle Partners Lori Milken Treasurer and Secretary Vice President Prostate Cancer Foundation James Blair Debbie Bohnett General Partner Chief Operating Officer Jerry Monkarsh Domain Associates Partner Stuart Holden, MD EJM Development Medical Director S. Ward (Trip) Casscells III, MD John Edward Tyson Distinguished Professor of Medicine and Henry L. Nordhoff Howard R. Soule, PhD Chairman, President and Executive Vice President, Vice President of Biotechnology Chief Executive Officer Discovery and Translation Jimmy Carter University of Texas HSC, Houston Gen-Probe Incorporated Gregg S. Britt Senior Vice President, David Ederer Nelson Peltz Chairman Chairman and Biopharmaceutical Research Ederer Investment Company Chief Executive Officer and Development Triarc Companies, Inc. Karen D. Stone David Epstein Lynda Resnick Senior Vice President, Vice Chairman Development R. Christian B. Evensen Roll International Scott Harvey Bert Roberts Senior Vice President, The Reverend Rosey Grier Consultant Corporate Alliances The Milken Family Foundation Richard Sandler Helen Hsieh Partner Vice President, Stuart Holden, MD Maron & Sandler Director, Louis Warschaw Prostate Finance and Administration Executive Vice Presiden Cancer Center, and Warschaw, t George H.W. Bush The Milken Family Foundation Jan Haber Robertson, Law Families Chair in Vice President, Prostate Cancer Events and Donor Relations J. Gary Shansby Cedars-Sinai Medical Center Chairman Medical Director TSG Consumer Partners, LLC Sarah Z. Evans Prostate Cancer Foundation Vice President, Communications Lester H. Smith Arthur Kern Partner Investor Shira Berman Smith Interests Vice President, David H. Koch Scientific Programs Executive Vice President Elaine Wynn Director Koch Industries Wynn Resorts The Honorable Earle I. Mack Senior Partner Stanley Zax Chairman and President The Mack Company Zenith National Insurance Corp. Bill Clinton Jeffrey A. Marcus Managing Director Crestview Advisors

34 Prostate Cancer Foundation 2006 Progress Report 35 Appeal for Support

Dear Friend, You have been a source of vital support for the Prostate Cancer Foundation and we thank you. To beat prostate cancer once and for all, the PCF must leverage the talents and resources of thousands of people and institutions around the world. We cannot do it alone. Your help has made a difference. Every day, the PCF reaches out to new individuals and organizations to join the fight – and appeals to you to stay in the battle with renewed and continued generosity. We are making progress, but we must not let up. Since 1993 there has been virtually no important discovery in this battle that the PCF has not funded or facilitated. But without your sustained support, the PCF cannot continue funding the research that is so crucial for ending the death and suffering from prostate cancer. Our new Chief Executive Officer and President, Dr. Jonathan Simons, believes that the treatment of prostate cancer has changed significantly just in the last couple of years and is now poised to change quite radically in the next few years to come. I have renewed hope for seeing greatly accelerated progress in the next five years. We are confident that the research we funded in 2006 will yield remarkable advances. You have a right to be excited by the work that you and other donors helped fund, and you can be encouraged that dedicated investigators are using your dollars to help combat this devastating disease – and that if we keep the funds coming, we have the potential to see new and even better treatment strategies emerge. Your generosity is crucial for the more than 2 million men, like me, who are currently battling this disease and the more than 234,000 others who were forced to join the battle in 2006. We’ve got to put this disease out of business…soon. Your giving is the biggest reason men battling this disease can have hope. Please give them more reason to hope today. With deep gratitude,

David A. Ederer Audit Committee Prostate Cancer Foundation Board of Directors

36 Prostate Cancer Foundation 2006 Progress Report 37 Donation Opportunities

The Prostate Cancer Foundation welcomes gifts of cash, securities, non-cash assets and gifts by Will or Living Trust. We also welcome contributions made in memory, in tribute or in honor of friends or loved ones.

Donations Please mail your check to:

Prostate Cancer Foundation 1250 Fourth Street Santa Monica, California 90401 To make an online contribution, please visit our website: www.prostatecancerfoundation.org To make a credit card donation, call 800.757.CURE (2873).

Memorial or Tribute Gifts Honor the memory of a loved one or celebrate the accomplishment of a friend or family member by helping others. Make a memorial or tribute gift and the PCF will send an acknowledgment card to the family or honoree.

Other Gift Suggestions Assets or property including appreciated stock and real estate. Bequest – Include a gift to the PCF in your Will. Name the PCF as the primary or contingent beneficiary on a life insurance policy. Rollover funds from your IRA as a gift to the PCF and avoid all tax on the rollover (valid through 2007 and applies to those 70 1⁄2 years and older).

Editors: Shira Berman, Sarah Evans, Katie Lambe Contributing Editors: Sean Grimes, Donovin Matthews, Shavaun Rigler Special Thanks: Photos courtesy of Jay Weise (front and back cover, pages 3, 6, 9, 12); Milken Family Foundation (pages 10, 13, 18, 20, 21, 22); Rich Cruse (pages 14, 15); HUGO BOSS (page 16); Giorgio Armani (page 17); Ned Dishman/NBAE (page 17); Golf Digest (page 19); Ling Li (pages 20, 21); Bob Each, David Higger, Sherman Miller, Ed Silhan (page 22) More Information: www.prostatecancerfoundation.org

36 Prostate Cancer Foundation 2006 Progress Report 37 1250 Fourth Street Santa Monica, CA 90401 Tel 800.757.CURE (2873) Fax 310.570.4701 www.prostatecancerfoundation.org