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Aphrodisiac Herbal Therapy for Erectile Dysfunction
Original Article Aphrodisiac Herbal therapy for Erectile Dysfunction Bharti Goel1, Neelesh Kumar Maurya2* 1Research Scholar Department of Foods and Nutrition, Government Home Science College, Panjab University, Chandigarh, India. 2 Research Scholar, Department of Foods and Nutrition, Institute of Home Science, Bundelkhand University, Jhansi, Uttar Pradesh, India. Abstract Erectile dysfunction (ED) or male impotence is described as an inability to maintain penile erection primarily endothelial and neuronal dysfunction which is partly characterized by decreased production of nitric oxide (NO). Male impotence can be caused by androgen deficiency in aging men, atherosclerosis, diabetes mellitus, spinal cord injury, high level of cholesterol, hypertension, prostate surgery, prostate and heart disease, penis anatomical deformity, social and psychological conditions as unhappy marital relationship, depression, and stress. Aphrodisiac is a drink or food that arouse sexuality. It can be categorized into three groups according to their action mode as follows: increase sexual pleasure substances, increase libido substances (arousal, sexual desire), and increase sexual potency (erection effectiveness). Various extracts of medicinal plants and orally active drugs such as vardenafil, sildenafil, and tadalafil are used to increase arterial blood flow for treating (ED) in southwest Asia. Hence, this paper review focuses on medicinal plants used as aphrodisiacs for scientific validation and management of erectile dysfunction (ED). Keywords: Aphrodisiacs, herbal plants, erectile dysfunction, penile erection INTRODUCTION care providers, testosterone replacement therapy for aging men has been practiced for many years but if the patient has Erectile dysfunction (ED) is a neurovascular condition that no clinical signs of androgen deficiency then testosterone involves endothelium of the corpora cavernosal arterial blood replacement therapy will have no clinical effect [13, 14]. -
Phenomenological Claim of First Sexual Intercourse Among Individuals of Varied Levels of Sexual Self-Disclosure
University of Montana ScholarWorks at University of Montana Graduate Student Theses, Dissertations, & Professional Papers Graduate School 2005 Phenomenological claim of first sexual intercourse among individuals of varied levels of sexual self-disclosure Lindsey Takara Doe The University of Montana Follow this and additional works at: https://scholarworks.umt.edu/etd Let us know how access to this document benefits ou.y Recommended Citation Doe, Lindsey Takara, "Phenomenological claim of first sexual intercourse among individuals of varied levels of sexual self-disclosure" (2005). Graduate Student Theses, Dissertations, & Professional Papers. 5441. https://scholarworks.umt.edu/etd/5441 This Thesis is brought to you for free and open access by the Graduate School at ScholarWorks at University of Montana. It has been accepted for inclusion in Graduate Student Theses, Dissertations, & Professional Papers by an authorized administrator of ScholarWorks at University of Montana. For more information, please contact [email protected]. Maureen and Mike MANSFIELD LIBRARY The University of Montana Permission is granted by the author to reproduce this material in its entirety, provided that this material is used for scholarly purposes and is properly cited in published works and reports. **Please check "Yes" or "No" and provide signature Yes, I grant permission ___ No, I do not grant permission ___ Author's Signature: Date: ^ h / o 5 __________________ Any copying for commercial purposes or financial gain may be undertaken only with the author's -
Refractory Period
اختﻻﻻت عمل جىسی َ آمُزش َمطاَري ٌذف کلی درس : آضىایی با اختﻻﻻت عمل جىسی َ آمُزش مىاسب در ایه مُارد اٌذاف کلی جلسات : ) جٍت ٌر جلسً یک ٌذف ( آضىایی با فازٌای مختلف سیکل پاسخ جىسی آضىایی با عُاملی ماوىذ سه ، دارَ ، بیماریٍا َ ......... تأثیر آوٍا بر مسائل جىسی آضىایی با مسائل جىسی در دَران وُزادی ، وُپایی ، خردسالی ، پیص از مذرسً َ دَران مذرسً آضىایی با مسائل جىسی دردَران بلُغ َ وُجُاوی آضىایی با فعالیتٍای جىسی َتغییرات آن در دَران بارداری َ ضیردٌی آضىآ آضىایی با کٍىسالی َ تأثیر آن بر مسائل جىسی آضىایی با بیماریٍای مختلف َ تأثیر آن ٌا بر مسائل جىسی آضىایی با اختﻻﻻت عمل جىسی َ طریقً مقابلً با آن Anatomy of the male reproductive system Testis Scrotum Penis Seminal vessicles, prostate gland, bulbourethral glands Epididymis, vas deferens, urethra TESTES Primary reproductive organs or gonads Production of sperm Suspended outside the body cavity by scrotum PENIS Deposits sperm in female Erectile tissue (vascular) Erection results from gorging tissue with blood Erection is a parasympathetic spinal reflex to tactile and other stimulation enhanced by sympathetic inhibition Provide the bulk of the semen, a mixture of secretions, sperm and mucous Fructose and prostaglandins from seminal vessicles Alkalinity and clotting enzymes from prostate Lubricant for intercourse from bulbourethral glands Epididymus, vas deferens, urethra: ejaculation Route of exit of sperm Ductus deferns stores sperm During emmission phase of ejaculation sperm are emptied into urethra by sympathetically induced contractions Motor neuron induced contractions -
11 A. Excitement. for Men, This Involves Erection of the Penis
A. Excitement. For men, this involves erection of the penis, which usually occurs within a few seconds after sexual stimulation begins. In addition, skin ridges of the scrotum smooth out and the testes are drawn towards the body. B. Plateau. In men, the diameter of the head of the penis increases slightly and deepens in color because of increased blood flow. Vasocongestion also causes the testes to swell, becoming 50 to 100 percent larger than in the unstimulated state. In addition, small amounts of clear fluid may sometimes be secreted from the Cowper’s gland and appear from the male urethra. C. Orgasm. Men ejaculate semen during this stage, which actually has two parts: First, men experience a sensation of ejaculatory inevitability, which occurs just before ejaculation begins. Second, contractions of the urethra, penis and prostate glad serve to expel semen from the head of the penis. D. Resolution. Immediately after ejaculation, men enter a refractory period, during which further orgasm or ejaculation is not possible. This time varies greatly between men and increases with age. A partial loss of erection occurs during the refractory period. Eventually, blood flow to the genitals returns to pre-excitement levels. (Masters and Johnson, 1966). For thirty years this model has served as the foundation for the study of human sexual response and sexual dysfunction. In the 1970s, Kaplan (1974) and later Lief (1977) identified a subset of individuals whose sexual dysfunction did not lie within the four stages described by Masters and Johnson (1966). Instead, these people experienced little interest in sexual activity. -
Male Anorgasmia: from “No” to “Go!”
Male Anorgasmia: From “No” to “Go!” Alexander W. Pastuszak, MD, PhD Assistant Professor Center for Reproductive Medicine Division of Male Reproductive Medicine and Surgery Scott Department of Urology Baylor College of Medicine Disclosures • Endo – speaker, consultant, advisor • Boston Scientific / AMS – consultant • Woven Health – founder, CMO Objectives • Understand what delayed ejaculation (DE) and anorgasmia are • Review the anatomy and physiology relevant to these conditions • Review what is known about the causes of DE and anorgasmia • Discuss management of DE and anorgasmia Definitions Delayed Ejaculation (DE) / Anorgasmia • The persistent or recurrent delay, difficulty, or absence of orgasm after sufficient sexual stimulation that causes personal distress Intravaginal Ejaculatory Latency Time (IELT) • Normal (median) à 5.4 minutes (0.55-44.1 minutes) • DE à mean IELT + 2 SD = 25 minutes • Incidence à 2-11% • Depends in part on definition used J Sex Med. 2005; 2: 492. Int J Impot Res. 2012; 24: 131. Ejaculation • Separate event from erection! • Thus, can occur in the ABSENCE of erection! Periurethral muscle Sensory input - glans (S2-4) contraction Emission Vas deferens contraction Sympathetic input (T12-L1) SV, prostate contraction Bladder neck contraction Expulsion Bulbocavernosus / Somatic input (S1-3) spongiosus contraction Projectile ejaculation J Sex Med. 2011; 8 (Suppl 4): 310. Neurochemistry Sexual Response Areas of the Brain • Pons • Nucleus paragigantocellularis Neurochemicals • Norepinephrine, serotonin: • Inhibit libido, -
Table of Contents
Fall 2011 Table of Contents Contents Announcing the Masters & Johnson Collection Kinsey library receives the archives of these pioneers in sex research. Mapplethorpe Foundation Donates Photographs 30 photographs by this influential 20-century artist donated to the Kinsey Collections. Researchers Present at Fall Conferences Kinsey Institute scientists and graduate students share their research. New Thought Leaders Join Kinsey Board Industry leaders contribute their expertise. Announcing the 2012 John Money Fellowship for Scholars of Sexology Graduate Student fellowship utilizes Kinsey Institute library and archives. Applications close December 22, 2011. In Memory: Don McMasters We honor the life of art enthusiast and Kinsey donor Don McMasters. Fall Events at The Kinsey Institute Filmmaker Monika Treut curates Kinsey films and Len Prince show opens. Hold the date! May 17-20, 2012, Eastern/Midcontinent Regions Meeting of SSSS at Indiana University. Hope to see you here. The mission of The Kinsey Institute is to promote interdisciplinary research and scholarship in the fields of human sexuality, gender, and reproduction. The Institute was founded in 1947 by renowned sex researcher Alfred Kinsey. Today, the Institute has two components, an Indiana University research institute and a not-for-profit corporation, which owns and manages the Institute's research data and archives, collections, and databases. The Masters & Johnson Collection The Kinsey Institute is pleased to announce the new “Masters and Johnson” collection at The Kinsey Institute library. The collection documents the work of William Masters and Virginia Johnson, who from 1957 to the 1980s transformed our understanding of sexual response and sex therapy. The collection, donated by Virginia Johnson and her family, includes letters, records, correspondence, research papers, media coverage, books, paintings, awards and certificates. -
Sexual Arousal and Performance Are Modulated by Adrenergic-Neuropeptide- Steroid Interactions
* 1995 Elsevier Science B. V. All rights reserved. The Pharmacology of Sexual Function and Dysfunction J. Bancroft, editor 55 Sexual Arousal and Performance are Modulated by Adrenergic-Neuropeptide- Steroid Interactions John T. Clark Department of Physiology, Meharry Medical College, 1005 D.B. Todd Boulevard, Nashville, Tennessee, 37208, U.S.A. Introduction Sexual function is regulated by a complex interaction between the nervous system, hormones and sexually relevant tissues. In addition to psychogenic causes, organic factors such as aging, hypertension, diabetes, renal failure, malnutrition, and obesity, as well as responses to medications used to treat these disorders, may all contribute to sexual dysfunction. Although the precise identification of the neurochemical messengers (and the appropriate neuroanatomical loci) underlying the expression of male sexual behavior remains to be elucidated, progress has been made. We feel that, with careful attention paid to the aspects of sexuality and the problems associated with continuous (or long-term) pharmacological/hormonal treatment, some degree of relief may be available for those exhibiting sexual dysfunction In our research in male rats, we have frequently observed a repression of sexual function. However, some treatments do facilitate aspects of sexual behavior. We have repeatedly observed two "prosexual" effects in male rats: a facilitation of the ejaculatory response; and a facilitation of sexual arousal. Other prosexual effects have been reported, typically an enhancement of erection. Assessment of Sexual Function Animal modeling of human sexual function is viable, and its usage is aimed at elucidating the biological factors affecting male sexual behavior [1-5]. Although it seems reasonable to test drugs for sexual effects in animals first, many clinically useful agents (including antihypertensives) have not been systematically studied. -
Asexuality: Dysfunction Or Sexual Orientation?
em & yst Se S xu e a v l i t D c i Reproductive System & Sexual s u o Parente and Albuquerque, Reprod Syst Sex Disord 2016, 5:3 d r o d r e p r e DOI:10.4172/2161-038X.1000185 s R Disorders: Current Research ISSN: 2161-038X Commentary Open Access Asexuality: Dysfunction or Sexual Orientation? Jeanderson Soares Parente1 and Grayce Alencar Albuquerque2* 1Faculdade de Juazeiro do Norte-FJN, Member of the Research Group on Sexuality, Gender, Sexual Diversity and Inclusion-GPESGDI 2Nursing Department, Universidade Regional do Cariri- URCA *Corresponding author: Albuquerque GA, Assistant Professor of the Nursing Department of the Universidade Regional do Cariri- URCA, Coordinator of the Observatory of Violence and Human Rights, Leader of the Research Group on Sexuality, Gender, Sexual Diversity and Inclusion-GPESGDI, Street Vicente Furtado, 521, Limoeiro, Juazeiro do Norte, Ceará, Brasil, Tel: +55-88-988878717; E-mail: [email protected] Rec date: July 2, 2016; Acc date: July 20, 2016; Pub date: July 27, 2016 Copyright: © 2016 Parente JS, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Abstract The objective was to perform a brief reflection on asexuality and its relationship with medical (pathologizing) and social (sexual diversity) practices. Asexuality is still considered a sexual dysfunction capable of medicalization in medical practice, although currently, with the visibility of sexual diversity, asexual identity has been breaking the paradigm of medicalization of sexuality. -
“Rauwolscine/ Alfa Yohimbine”
“Rauwolscine/ Alfa Yohimbine” Rauwolscine / Alfa Yohimbine – Natural and Safe Alternative for FAT BURNING Rauwolscine or Alfa–Yohimbine is an indole alkaloid with stimulant, aphrodisiac and local anaesthetic effects found naturally in plants of the genus Rauwolfia and Pausinystalia, along with several other active alkaloids including Yohimbine. Rauwolscine is a stereoisomer of Yohimbine, that is it is chemically identical, but differs in its 3 dimensional orientation. There are a total of 3 stereoisomers of Yohimbine, the other two are corynanthine and 3-epi-alpha-yohimbine. How it works – science behind this natural supplement Fat-Burning Potential Rauwolscine, or {3H}Rauwolscine, is a potent and selective antagonist of alpha-2 adrenergic receptors. This is the same mechanism by which yohimbine acts by blocking the pre- and post-synaptic alpha-2 adrenoceptors, this prevents the release of Norepinephrine from cells. Norepinepherine stimulates both the alpha and beta receptors in a cell. Stimulation of the beta adrenoceptors causes the breakdown of fat, whilst stimulating the alpha-2 adrenoceptors prevents this breakdown of fats.Alfa Yohimbine (Rauwolscine) blocks the alpha feedback mechanism, thus increasing norepinephrine. Additionally in blocking the alpha-2 receptor it blocks the storage of new fat. Serotonergic Effects Its works in a similar fashion like yohimbine, rauwolscine is an agonist of 5-HT1a/b receptors and induces serotonin-like effects.Whereas yohimbine has more affinity for the receptor, rauwolscine has a lower IC50 value (meaning it can saturate more receptors at the same dose) and can be seen as slightly more potent in serotonergic activity. Rauwolscine, an antagonist radioligand for the cloned human 5- hydroxytryptamine2b (5-HT2B) receptor. -
Case Report Absence of Orgasm-Induced Prolactin Secretion in a Healthy Multi-Orgasmic Male Subject
International Journal of Impotence Research (2002) 14, 133–135 ß 2002 Nature Publishing Group All rights reserved 0955-9930/02 $25.00 www.nature.com/ijir Case Report Absence of orgasm-induced prolactin secretion in a healthy multi-orgasmic male subject P Haake1, MS Exton1*, J Haverkamp1, M Kra¨mer1, N Leygraf2, U Hartmann3, M Schedlowski1 and THC Krueger1 1Department of Medical Psychology, University Clinic of Essen, Essen, Germany; 2Department of Forensic Psychiatry, University Clinic of Essen, Essen, Germany; and 3Department of Clinical Psychiatry, Hannover Medical School, Hannover, Germany In several studies we have recently demonstrated that orgasm induces prolactin secretion in healthy males and females. This suggests that prolactin may form a feedback regulator of the refractory period following orgasm. To examine this position we investigated the prolactin response of a healthy multi-orgasmic male subject. Blood was drawn continuously during masturbation-induced orgasm. The prolactin response of the case-subject was compared with that of nine healthy adult men with a normal refractory period. The case-subject showed no prolactin response to three orgasms. Data from this multi-orgasmic subject support the hypothesized role of plasma prolactin in contributing to sexual-satiation mechanisms. International Journal of Impotence Research (2002) 14, 133–135. DOI: 10.1038=sj=ijir=3900823 Keywords: sexual arousal; prolactin; multi-orgasmic; model; refractory period; neuroendo- crinology Introduction fulfilling the criteria for multi-orgasmic and multi- ejaculatory males.7 Sexual dysfunction is a commonly reported side effect of psychiatric medication, underscoring the importance of neuroendocrine mechanisms in reg- Methods ulating sexual competence.1,2 Thus, we recently designed a continuous blood sampling technique and sexual arousal paradigm to investigate endo- The case subject (aged 25 y) reported an average crine mechanisms regulating sexual arousal. -
MASTERS of SEX by Michelle Ashford
MASTERS OF SEX by Michelle Ashford First Draft, Revised June 28, 2011 EXT. RITZ CARLETON HOTEL - CARONDELET PLAZA - NIGHT A busy downtown sidewalk illuminated by the lamps of the hotel overhang. A DOORMAN moves to the curb, opens the door of a sleek Ford Fairlane. Well-heeled guests emerge, VANISH behind the heavy brass doors. A VOICE drifts to the surface. VOICE (O.S.) ... a bellwether in the field of obstetrics and gynecology. Maternity Hospital has set a new standard in the Midwest. The highest standard. SUPER: RITZ CARLETON HOTEL - ST. LOUIS, MISSOURI - 1956 VOICE (O.S.) (CONT’D) So high that even our friends on the coasts are now paying attention. A RIPPLE of laughter, as we go... INT. BALLROOM - CONTINUOUS Black tie. Filled to capacity. CHANCELLOR SHEPLEY speaks from the podium, bestows his benevolent gaze on DR. WILLIAM MASTERS. Masters sits at the head table, stares into middle space with a vague frown, rubs his finger along the base of his water glass. He doesn’t appear to notice the SQUEAK. Shepley continues to tout his hospital’s accomplishments, as LIBBY MASTERS places her hand over her husband’s to settle him. Gives a smile. Masters SIGHS, as the woman on his other side, DODIE BRODHEAD, leans toward Libby with a loud WHISPER. DODIE ... it was the January House & Garden. Because they were the first, I’m quite sure of it, to introduce the whole idea of cork flooring. LIBBY I think I saw it in Woman’s Day. Masters remains deaf to this CHATTER as we follow his GAZE. -
Is Changing Sexual Orientation a Viable Option for Ego-Dystonic
DOCUMENT RESUME ED 275 919 CG 019 451 AUTHOR Keener, Dana Ray TITLE Is Changing Sexual Orientation a Viable Option for Ego-Dystonic Homosexuality? PUB DATE Aug 86 MOTE 69p.; Doctor of Psychology Research Paper, Biola University, California. PUB TYPE Information Analyses (070) EDRS PRICE MF01/PC03 Plus Postage. DESCRIPTORS Attitude Change; Behavior Change; *Behavior Modification; *Group Therapy; *Homosexuality; Life Style; *Psychotherapy; *Self Help Programs; *Sexual Identity ABSTRACT This paper addresses the issue of homosexuals who want to change their sexual orientation. It is noted that many ego-dystonic homosexuals who want to become heterosexual, despite e ncouragement from psychotherapists to accept their homosexuality, are turning to self-help groups in an effort to change their sexual orientation. Studies that have attempted to change sexual orientation are reviewed in this paper. Problems with defining and measuring change in sexual orientation are considered and the importance of therapies for changing sexual orientation is discussed. Studies involving psychoanalytic therapies are reviewed. Several studieson behavior therapies are examined, including studies of aversion therapy, classical conditioning, and systematic desensitization. Studies dealing with group therapy are discussed under the headings of heterogeneous groups, homogeneous groups, and self-helpgroups. Problems associated with each type of therapy are noted. Thepaper concludes that studies in which changes in sexual orientationseem most complete involve a change in lifestyle whereby the person takes on a new social and sexual identity. It is asserted that psychotherapists can offer better help to homosexuals desiring to change their sexual orientation as aspects of sexual identity and lifestyle are more fully addressed. (Author/NB) *********************************************************************** * Reproductions supplied by EDRS are the best that can be made * * from the original document.