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Volume 139 Number 1 January 2014 ISSN: 0971-5916
Estd : 1913 Submit online: littp://\v>v>v.journalonweb.coiii/ijnir
THE INDIAN JOURNAL OF MEDICAL RESEARCH
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INDIAN COUNCIL OF MEDICAL RESEARCH NEW DELHI
www.ijmp.org.ip Indian J Med Res 139, January 2014, pp 1-184
Contents
Editorial Alzheimer's disease prevention & acetyl salicylic acid: a believable story Massimiliano Pomponi & Massimo F.L. Pomponi Commentaries Approach to the diagnosis ofdevelopmental delay - The changing scenario Neerja Gupta & Madhulika Kabra India can do more about intestinal worm infections Nilanthi de Silva
Review Articles Role ofgut pathogens in development ofinitable bowel syndrome Madhiisudan Grover Probiotic foods: Can their increasing use in India ameliorate the burden of chronic lifestyle disorders? Neerja Hajela, G. Balakrish Nair, B.S. Ramah'ishna & N.K. Ganguly Distribution ofgenetic polymorphisms ofgenes encoding drug metabolizing enzymes & drug transporters - a review with Indian perspective Gurusamy Umamaheswaran, Dhakchinamoorthi Krishna Kumar & Chandrasekaran Adithan Original Articles Clinical utility ofmultiplex ligation-dependent probe amplification technique in identification ofaetiology of unexplained mental retardation: A study in 203 Indian patients Vy'ay R. Boggula, Anju Shukla, Siimita Danda, Sankar V. Hariharan, Sheela Nampoothiri, Rashmi Kumar <& Shubha R. Phadke Prevalence & risk factors for soil transmitted helminth infection among school children in south India Deepthi Kattula, Rajiv Sarkar, Sitara Swarna Rao Ajjampur, Shantidani Minz, Bruno Levecke, Jayaprakash Muliyil & Gagandeep Kang Association between obstetric complications & previous pregnancy outcomes with current pregnancy outcomes in Uttar Pradesh, India Deepti Singh, Srinivas Goli & Sulabha Parsuraman Endophthalmitis patients seen in a tertiaiy eye care centre in Odisha: A clinico-microbiological analysis Savitri Sharma, Tapas R. Padhi, Sownyava Basu, Sarita Kar, Arvind Roy & Taraprasad Das Prevalence ofGraves' ophthalmopathy in patients with Graves' Jisease presenting to a referral centre in north India Sagiii Vijaya Bhaskar Reddy, Ami Jain, Subhash B. Yadav, Kimnidini Sharma & EeshBhalia Molecular genotyping ofABO blood groups in some population groups from India Sabita Ray, Ajit C. Gorakshakar, K. Vasantha, Anita Nadkarni, Yazdi Italia & Kanjaksha Ghosh Efficacy & safety ofcontinuous erythropoietin receptor activator (CERA) in treating renal anaemia in diabetic patients with chronic kidney disease not on dialysis Sameer G. Vankar. Pinaki Dutta, H.S. Kohli & Anil Bhansali (iv) Contents Pages
Validity of SW982 synovia! cell line for studying the drugs against rheumatoid arthritis in fluvastatin-induced apoptosis signaling model Jae-Ho Chang, Kyu-Jae Lee, Soo-Ki Kim, Dae-Hyun Yoo & Tae-Young Kang ... 117 Expressional regulation of genes linked to immunity & programmed development in human early placenta! villi M.A. Khan, S. Manna, N. Malhotra, J. Sengupta & D. Ghosh 125 Bio-medical waste management: situational analysis & predictors of performances in 25 districts across 20 Indian States INCLEN Program Evaluation Network (IPEN)study group. New Delhi, India ... 141 Clinical profile & predictors of poor outcome of adult HlV-tuberculosis patients in a tertiary care centre in north India Surendra K. Sharma, Manish Soneja, K.T Prasad & Sanjay Ranjan 154 Polymerase chain reaction targeting insertion sequence for the diagnosis of extrapulmonary tuberculosis V. Makeshkumar, Radha Madhavan & Sujatha Narayanan Survival of diumally sub periodic Wuchereria bancrofti in Downsiomyia nivea (Diptera: Culicidae): a density dependent factor from Andaman & Nicobar Islands A.N. Shriram, K. Krishnamoorthy & P. Vanamail jgy Student IJ?i1R Assessment of stress & related albuminuria in caregivers of severe mentally ill persons Anirban Dalui, Prathama Guha, Angshuman De, Sandip Chakraborty & Indranil Chakraborty 174 Correspondence The relationship between the use of fluconazole & the incidence of fluconazole-resistant Candida species Chia-Chang Kuo & Chien-Ming Chao jyg Authors' response J.K. Oberoi, C. Wattal, N. Goel, R. Raveendran, S. Datta & K. Prasad 278 Clinical Images Stewart-Treves syndrome Marek Stcinczyk & MagdaJena Gewartowska j A case of pycnodysostosis presented with pathological femoral shaft fracture Shailendra Singh & Balaji Sambandam j Book Reviews The evolving threat of antimicrobial resistance: Options for action jg2 WHO qualityRights tool kit: Assessing and improving quality and human rights in mental health and social care facilities jg^ Book Received ^g^ Guidelines for Contributors , . (v) Indian J Med Res 139, February 2014, pp 185-332
Contents
Editorial Pages Debunk the myths: Oncologic misconceptions Jaydip Biswas 185 Commentaries Depression in primarycare: challenges & controversies Ajit Avasthi & Abhishek Ghosh 188 Ethical challenges 8c dilemmasfor medicalhealth professionals doing psychiatric research Manjulika Vaz <& K. Srinivasan 191 Review Articles
Opportunistic invasive fungal infections: diagnosis & clinical management • Parisa Badiee & Zahra Hashemizadeh 195 Antimalarial drug policy in India: Past, present & future AnupkumarR. Anvikar, UshaArora, GS. Sonal, Neelima Mishra, Bharatendu Shahi, DeepaliSavargaonkar, Navin Kumar, Naman K. Shah &Neena Valecha 205 Breast cancer painmanagement -A review of current & novel therapies AanchalSatija, SyedMehmood Ahmed, RahulGupta, ArifAhmed, Shiv Pratap Singh Rana, Suraj Pal Singh, Seema Mishra & Sushma Bhatnagar 216 Special Reports 1 ICMRprogramme onAntibiotic Stewardship, Prevention of Infection & Control (ASPIC) 't SujithJ. Chandy, Joy SarojiniMichael, Balaji Veeraraghavan, O.C. Abraham, Sagar S. Bachhav & Nilima A. Kshirsagar 226 Perceptions of State Government stakeholders & researchers regarding public health research priorities in India:An exploratory survey Prabhdeep Kaur, Grace A. Chitra, Sanjay M. Mehendale& Vishwa M. Katoch 231 Original Articles Enhanced careby community health workers in improving treatment adherence to antidepressant medication in rural women with major depression Johnson Pradeep, Anton Isaacs, DeepthiShanbag, SumithraSelvan iSc Krishnamachari Srinivasan 236 Knowledge &attitudes of mental health professionals regarding psychiatric research N.N. Mishra, Triptish Bhatia, Nandini Kumar, Vishwajit L. Nimgaonkar, LisaS. Parker cfe Smita N. Deshpande 246 High prevalence ofcardiovascular risk factors inAsian Indians^ Acommunity survey - Chandigarh Urban Diabetes Study (CUDS) Rama Walia, Anil Bhansali, Muthuswamy Ravikiran, PadalaRavikumar, Sanjay K. Bhadada, G. Shanmugasundar, Pinaki Dutta & NareshSachdeva 252 A single hospital study onportal vein thrombosis in cirrhotic patients - clinical characteristics & risk factors Huisong Chen, Goolab Trilok, Fei Wang, Xiaolong Qi, Junjie Xiao &Changqing Yang 260 Early evaluation ofmagnetic resonance imaging guided focused ultrasound sonication in the treatment ofuterine fibroids Y. Himabindu, M. Sriharibabu, Vinay Nyapathy &Anindita Mishra 267
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f<- -'i •.vj Contents a-Adducin gene G614Tpolymorphisms in essential hypertension patientswith high low density lipoprotein (LDL) levels Lifang Wang, BinZheng, Hongguang Zhao, Peng Du, Aihua Sun, Kouzhen Hua c& Yuyu Gao Effect ofgender, biochemical parameters & parathyroid surgery on gastrointestinal manifestations ofsymptomatic primary hyperparathyroidism Viral N. Shah, Sanjay KumarBhadada, AnilBhansali, A. Behera,Anish Bhattacharya, Uma Nahar, Deepak Bhasin &. Bhavin Vadera Effect of public-private partnership in treatment of sexually transmitted infections among female sex workers in Andhra Pradesh, India Suresh Babu Kokku, Bidhubhusan Mahapatra, Saroj Tucker, NiranjanSaggurti& Parimi Prabhakar Response ofmalaria vectors to conventional insecticides in the southern districts ofOdisha State, India S.S. Sahu, K. Gunasekaran, H.K. Raju, P. Vanamail, M.M. Pradhan & P. Jambulingam Lymph nodes cytology in HIV seropositive cases with haematological alterations Neelima Tirumalasetti & P. Prema Latha Role of 72 kDa protein ofLeptospira interrogans asa diagnostic marker inacute leptospirosis M. Riazi, F.Z. Zainul, A.R. Bahaman, F. Amran & A. Khalilpour Correspondences High frequency of young age rectal cancer in a tertiary care centre of southernAssam, North East India Ruhina Shirin Laskar, Fazlur Rahman Talukdar, Rosy Mondal, Ravi Kannan t&. Sankar Kumar Ghosh In vitro evaluation ofantibiotics for methicillin-resistant Staphylococcus aureus from north India AbhishekMewara, Vikas Gautam, Harsimran Kaur & Pallab Ray Need to revisit vitamin A supplementation programme in India J.K Raman & Deepika Nayar Chaudhery Authors' response H.P.S. Sachdev & Umesh Kapil Clinical Images A rare type ofpartial anomalous pulmonary venous return in late diagnosed patients AH Kemal Sivrioglu & Giiner Sonmez Exogenous ochronosis Avninder Singh & V Ramesh Book Reviews WHO Study Group on Tobacco Product Regulation WHO Expert Committee on Leprosy Some Forthcoming Scientifc Event Form IV Guidelines for Contributors
WW:'- Indian J Med Res 139, March 2014, pp 333-480
Contents Editorial Pages Tuberculosis in India - Can we ensure a test, treatment & cure for all? Soumya Swaminathan ... 333 Commentaries Alielic variability in PSA & AR genes: A novel biomarker on the horizon for carcinoma prostate RN. Dogra ... 337 Probiotics for diarrhoea SusameHempel ... 339 Review Articles Migraine & paediatric obesity: a plausible link? SaritRavid ... 343 Cytogenomics of hexavalent chromium (Cr^)exposed cells: A comprehensive review Akanksha Nigam, Shivam Priya, Preeti Bqjpai Antibiotic susceptibilities, streptococcal pyrogenic exotoxin gene profiles among clinical isolates Editorial ofgroup C or GStreptococcus dysgalactiae subsp. equisimilis &ofgroup G S. anginosus group at a tertiary care centre Bijayini Behera, Purva Mathur, Nidhi BhardwaJ, Neetu Jain, M.C. Misra, Tuberculosis in India - Can we ensure a test, treatment & cure for all? Arti Kapil & Sarman Singh 438 Attenuation ofquorum sensing controlled virulence ofPseudomonas aeruginosa bycranberry Kiisum Harjai, Ravi Kumar Gupta & Himanshi Sehgal 446 Clinical profile & outcome ofHlNl infected pregnant women in a tertiary care teaching hospital ofnorthern India that can predict this event. Further, one of the many Seema Singhal, Nivedita Sarda, Renu Arora, Nikky Punia & AnilJain With a quarter of the world's tuberculosis (TB) 454 patients living in India, an estimated 2.3 million new survival mechanisms of the bacterium is the fact that it Demographics ofanimal bite victims & management practices in a tertiary care institute in cases and 300,000 deaths each year, the disease is a resides within macrophages, utilizing many pathways Mumbai, Maharashtra, India massive public health challenge for the country'. to subvert the host immune system and resist killing^ NJ. Gogtay, A. Nagpal, A. Mallad, K. Patel, S.J. Stimpson, A. Belur & U.M. Thatte 459 The theme of this year's World TB Day is "Reach In India, the prevalence of latent TB infection (LTBI) A c;9--positive clinical staphylococcal isolate from India with multiple mechanisms the three million: A test, treatment and cure for all" is 50-60 per centin the adultpopulation and the annual risk ofTB infection ranges fi-om 1-1.6 per cent^. of linezolid-resistance - highlighting the fact that only about two-thirds of Vineeth Rajan, Vijay Gowdara Shankarappa Kumar & Shubha Gopal 463 the estimated 9 million new TB cases are reported The Revised National TB Control Programme Correspondences to national TB programmes and subsequently to the was introduced in 1993 (as a pilot programme and Fading chikungunya feverfrom India: beginning of the end of another episode? World Health Organization every year. In India, while later expanded to cover the entire country by 2006) approximately 1.5 million TB patients are notified and to replace the older National TB Programme. The M. Muniaraj 468 treated in the Revised National TB Control Programme new Programme included certain key elements that Reliability of Mycobacterial Growth Indicator Tube (MGIT) 960for the detection of isoniazid (RNTCP), an estimated 1 million are "missing"^ A were lacking earlier - standardized diagnosis based resistance in a tuberculosis endemic setting majority of these patients are probably treated in the on sputum smear microscopy, adequate supply of N.S. Gomathi & Vanaja Kumar 471 private sector, while an unknown number are either high quality drugs in patient-wise boxes, directly Clinical Images missed, misdiagnosed or die before a diagnosis can be observed treatment to ensure adherence and a reporting A rare cause ofleft back pain made. In order to make appropriate national plans and framework that allowed constant monitoring. The fifth Chang-Han Lo & Heng-Cheng Chii 474 policies to control TB, it is important to understand component ofthis so called "DOTS strategy" is political Poland's anomaly the true burden ofTB in the community, as well as its will - strong government support that ensured adequate distribution, risk factors, health seeking behaviour and MittalAliza & Kailash Chandra Aggarwal 476 financing and human resources. The Programme has pathways ofcare that patients use. This will be possible Book Reviews been consistently achieving the global targets for new only when there is full compliance with TB notification smear positive case detection (70%) and treatment Pituitary Today II: New molecular, physiological and clinical aspects 477 through NIKSHAY, an online portal launched by the success (85%) for the past ten years, and prevalence Urbanising cholera: The social determinants of its re-emergence 478 Government of India in May 2012-\ and mortality rates have been reduced in line with Some Forthcoming Scientifc Events 480 Millennium Development Goals (MDGs^. However, Tuberculosis has been known since ancient times, Guidelines for Contributors incidence is falling very slowly and the disease is still (V) and its causative agent Mycobacterium tuberculosis, ahuge public health problem, with 300,000 deaths and is well known for its adaptation to the human host. USD 23.7 billion the direct and indirect costs of TB Biologically, one of the challenges of controlling TB every year^ is that the bacterium can survive in a dormant or latent state, and re-activate to produce clinical disease, over a The question arises as to why, despite a well span of anentirelifetime"*. Thereasons for re-activation functioning programme and all the resources that have in a particular individual are still incompletely been allocated, TB continues to infect and kill hundreds understood and no biomarker has been developed of thousands of Indians each year. The answers can This editorial ispublished on the occasion ofWorld Tuberculosis Day - March 24. 2014. • •nrv •i,' Indian J Med Res 139, April 2014, pp 481-656 Contents Editorial World Health Day 2014: an opportunity topromote research onvectors &vector-bome diseases Leonard Ortega Commentaries Tobacco cessation in India:Apriority health intervention K. R. Thankappan NewHPV16 viral biomarkers to understand the progression of cervical lesions towards cancer Jean-Luc Pretet, David Guenat, Didier RiethmuUer & Christiane Mougin Review Articles A brief history of vaccines& vaccination in India Chandrakant Lahariya Role of neural modulation in the pathophysiology of atrial fibrillation Shailesh Male & Benjamin J. Scherlag Original Articles Tobacco cessation outcomes ina cohort of patients attending a chest medicine outpatient clinic in Bangalore city, southern India P.K. Mony, D.P Rose, P. Sreedaran, G. D 'Souza & K. Srinivasan Physical state © number ofhigh risk human papillomavirus type 16 DNA in progression of cervical cancer Shirish Shukla, Sutapa Mahata, Gauri Shishodia, Shailja Pande, Gaurav Verma, SureshHedau, Suresh Bhambhani, ArchanaKimari, SwarajBatra, Seemi F Basin Bhudev C. Das & Alok C. Bharti An approach for conjugation of'"Lu- DOTA-SCN- Rituximab (BioSim) &its evaluation for radioimmunotherapy ofrelapsed &refractory B-cell non Hodgkins lymphoma patients Parul Thah'al, Suhas Singla, Madhav Prasad Yadav, Atul Vasisht, Atul Sharma, Santosh KumarGupta, C.S. Bal, Snehlata&AnmMalhotra Bioevaluation of'~^I Ocu-Prosta seeds for application inprostate cancer brachytherapy Archana Mukherjee, Haladhar Dev Sarma, Sanjay Saxena, Yogendra Kumar. Pradip Chaudhari. Jayant Sastri Goda, Pranjal Adurkar. Ashutosh Dash &Grace Samuel Downregulated inhibitor ofgrowth 3(ING3) expression during colorectal carcinogenesis Wen-feng Gou, Hong-zhi Sun, Shuang Zhao, Zhe-fengNiu, Xiao-Yun Mao, Yasuo Takano & Hua-chuan Zheng Role ofoxidative stress &antioxidant defence in ulcerative colitis patients from north India S. V. Rana, S. Sharma, K.K. Prasad, S.K. Sinha & K. Singh CYP4F2 1347 G>A & GGCX12970 C>G polymorphisms: frequency in north Indians & their effect on dosing of acenocoumarol oral anticoagulant Saurabh Singh Rathore, Surendra Kumar Agarwal, Shantanu Pande, Sushil Kumar Singh, Tulika Mittal & Balraj Mittal Blood count innew onset atrial fibrillation after acute myocardial infarction - Ahypothesis generating study Klaus Distelmaier, Gerald Maurer & Georg Goliasch Pasteurization ofbone for tumour eradication prior to reimplantation - An in vitro &pre-clinical efficacy study . • p • Jyoti Kode. Prasad Taur, Ashish Gulia, Nirmala Jambhekar, Manish Agarwal &Ajay Pun Age related secretary pattern of growth hormone, insulin-like grovrth factor-I &insulin-like growth factor binding protein-3 in postmenopausal women Akbar Alinsgarzadeh. Morteza Ghojazadeh, Reza Haji-Hoseini. Faezeh Mehanfar, Reza Piri, Mohammad Naghavi-Behzad &Nariman Nezami (iv) Contents Pages Covalent immobilization of lipase, glycerol kinase, glycerol-3-phosphate oxidase & horseradish peroxidase onto plasticized polyvinyl chloride(PVC) strip & its application in serum triglyceride determination Nidhi Chauhan, Jagriti Narang & Chandra Shekhar Pundir ... 603 Safety evaluation of mercury based Ayurvedic formulation {Sidh Makardhwaj) on brain cerebrum, liver & kidney in rats Gajendra Kumar, Amita Srivastava, Surinder Kumar Sharma & Yogendra Kumar Gupta ... 610 Effect of active immunization against angiotensin II type 1 (ATI) receptor on hypertension & arterial remodelling in spontaneously hypertensive rats(SHR) Liu-Dong Li, Miao Tian, Yu-Hua Liao, Zi-Hua Zhou. Fen Wei. Feng Zhu, Min Wang, Bin Wang & Yii-Miao Wei ... 619 Phenotypic identification & molecular detection of bla„d„,.i gene in multidrug resistant Gram-negative bacilli in a tertiary care centre Anjana Shenoy K., Jyothi E.K. & R. Ravikiimar ... 625 Detection & characterization of necrotoxin producing Escherichia coli(NTEC) from patients with urinary tract infection (UTI) Helina Rahman & Manab Deka ... 632 Student UMR Predictors of quitting behaviour with special reference to nicotine dependence among adult tobacco-users in a slum of Burdwan district, West Bengal, India Kamirul Islam, Indranil Saha, Rajib Saha, Sufi Abdul Samim Khan, Rupali Thakur & Swapnil Shivam 638 Correspondences Multi-drug resistance in clinical isolates of Gram-negative bacilli in a tertiary care hospital of Assam Himadri Duita, Reema Nath & Lahari Saikia ^43 Susceptibility testing of Staphylococaus aureus V. Anil Kumar . 646 Authors' response Sheetal Chilnis, Gunjan Katara, Nanda Hemavani, Siddika Pareek & Dhananjay Sadashiv Chitnis ... 646 Clinical Images Potter's syndrome - a fatal constellation of anomalies M.G. Manoj & S. Kakkar 648 Queyrat erythroplasia accompanied by bladder cancer in a circumcised male Savas Oztiirk & Haydar U(^ak Book Reviews 9 Clinical assessment and management of childhood psychiatric disorders ^52 Polycystic ovary syndrome; Novel insights into causes and therapy ^^3 Some Forthcoming Scientific Events ^55 Guidelines for Contributors Indian J Med Res 139, May 2014, pp 657-792 Contents Editorials Pages Towards better hypertension management in India Rajeev Gupta & Salim Yiisuf ••• 657 Obesity - a risk factor or a disease. What can exercise do for obese children? Jose M. Saavedra 661 Commentary Need for a nomogram of renal sizes in the Indian population Egberongbe Adedeji — 663 Review Articles Progeria: A rare genetic premature ageing disorder Jitendra Kumar Sinha, Shampa Ghosh & Manchala Raghunath ... 667 Human mammaglobin in breast cancer: a brief review of its clinical utility Fawwaz Shakir AlJoudi ••• 675 Original Articles Need for a nomogram of renal sizes in the Indian population- findings from a single centre sonographic study Prakash Muthusami, Ramesh Ananthahishnan & Poyyamoli Santosh ... 686 Changes in clinical & biochemical presentations of primary hyperparathyroidism in India over a period of 20 years Viral N. Shah, Sanjay Kumar Bhadada, Anil Bhansali. Arnanshu Behera & B.R. Mittal ... 694 A 4-compartment model based validation of air displacement plethysmography, dual energy X-ray absorptiometry, skinfold technique & bio-electrical impedance for measuring body fat in Indian adults Rebecca Kiiriyan. Tinku Thomas, Sangeetha Ashok, Jayakumar J. & Anura V Kurpad ... 700 Profile of inhalant users seeking treatment at a de-addiction centre in north India Sunil Gupta, Naresh Nebhinani, Debasish Basu & Siirendra Kumar Mattoo ... 708 Role of computed tomography(CT) scan in staging of cervical carcinoma TV. Prasad. S. Thulkar, S. Hari, D.N. Sharma & S. Kumar ... 714 Copy number polymorphism of glutathione-S-transferase genes (GSTMl & GSTTJ) in susceptibility to lung cancer in a high-risk population from north-east India Rakhshan Ihsan, Pradeep Singh Chauhan, Ashwani Kumar Mishra. L.C. Singh, Jagannath Dev Sharma, Eric Zomawia, Yogesh Verma, Sijala Kapur & Sunita Saxena ... 720 Associations between androgen receptor CAG & GGN repeat polymorphism & recurrent spontaneous abortions in Chinese women Zhang Chiian. Dang Jie, Xu Hao, Bao Junhiia, Guo Mengjing. Pei Liguo, Yan Yousheng, Lu Hong & Huo Zhenghao ... 730 Association of interleukin-lO with hepatitis B virus(HBV) mediated disease progression in Indian population Roii Saxena. Yogesh Kumar Chawla. Indii Verma & Jyotdeep Kaur Induction of resistant mutants of Salmonella enterica serotype Typhi under ciprofloxacin selective pressure Sushila Dahiva. Arti Kapil. Rakesh Lodha. Ramesh Kumar. Bimal Kumar Das. Seema Sood & S.K Kahra 746 (i^) Contents Pages Entomological investigations into an epidemic of Japanese encephalitis (JE) in northern districts of West Bengal, India (2011-2012) T. Mariappan, P. Philip Samuel, V Thenmozhi, R. Paramasivan, Puran Kumar Sharma, Asit Kumar Biswas & B.K. Tyagi 754 Serratia odorifera mediated enhancement in susceptibility ofAedes aegypti for chikungunya virus Anjali D. Apte-Deshpande, MandarS. Paingankar. Mangesh D. Gokhale & Dileep N. Deobagkar Isolation of Chandipura virus {Vesiculovirus: Rhabdoviridae) from Seigentomyia species of sandflies from Nagpur, Maharashtra, India ' A.B. Sudeep. VP Bondre, Y.K Gurav, M.D. Gokhale, G.N. Sapkal, M.S. Mavale, R.P George & A.C. Mishra ^ 759 Low vaccine efficacy of mumps component among MMR vaccine recipients in Chennai, India Jeevan Malaiyan & Thangam Menon 773 Correspondences Rapid detection of Brucella by an automated blood culture system at a tertiary care hospital of north India , Atul Raj, Vikas Gaiilam, Puneet Kumar Gupta, Sunil Sethi, Sudesh Rana & Pallab Ray ... 776 Rare manifestation of multiple endocrine neoplasia type 2A & cutaneous lichen amyloidosis in a family with RET gene mutation Shweta Birla, Rajiv Singla, Anmdhati Sharma & Nikhil Tandon ' 779 Pathogenicity of avian influenza HI IN! virus isolated from wild aquatic bird Eurasian Spoonbill (Platalea leucorodia) Santosh S. Koratkar, Shailesh D. Pawar, Vijay N. Shelke, Sandeep D. Kale &. Akhilesh C. Mishra ... 782 Clinical Images '^F FDG PET/CT identifies unsuspected bilateral adrenal histoplasmosis in an elderly immuno compromised patient S. Padma & Sreekala Sreehari ... 786 Triple torus palatinus Wen-Sen Lai & Cheng-Ping Shih 788 Book Reviews Neurocognition and social cognition in schizophrenia patients: Basic concepts and treatment ... 789 Attention-deficit hyperactivity disorder(ADHD) in adults 79O Book Received 791 Some Forthcoming Scientific Events ^ 792 Guidelines for Contributors ^^7 IndianJ Med Res 139, June 2014, pp 793-970 Contents Editorial Pages Acentury after discovery ofsickle cell disease: keeping hope alive! Dipika Mohanty Commentaries Developmental trajectory ofsubstance use disorders: What role do the parents play (or are perceived to play)? Debasish Basil & Abhishek Ghosh Adiponectin & inflammatory biomarkers incoronary artery disease Jaewon Oh & Seok-Min Kang Prostate biopsy for elevated prostate specific antigen (PSA) - Indian perspective • N. Ragavan Review Articles Foodallergy: Diagnosis, management & emerging therapies Rachel Glick Robison Prevention ofventilator-associated pneumonia in the intensive care unit: A re^'iew ofthe clinically relevant recent advancements HoUy Keyt, Paola Faverio & Marcos I. Restrepo Obesity-related inflammation &cardiovascular disease: Efficacy ofa yoga-based lifestyle intervention Kumar Sarvottam & Raj Kumar Yadav Original Articles Perceptions ofparental bonding in freebase cocaine users versus non-illicit drug users Marcia Pettenon, Felix Henrique Paim Kessler, Luciano S.P Giiimaraes, Rosemeri SiqueiraPedroso, Simone Hauck& FlavioPechansky Comparison of plasma adiponectin &certain inflammatoiy markers in angiographically proven coronary artery disease patients with & without diabetes - A study from India Satyavani Kumpatla. Kirubakaran Karuppiah, Sathyamiirthy Immaneni, Parthiban Muthukumaran, JayanthiKrishnan, Srinivasan Kanthalhi Narayanamoorthy & Vijay Viswanathan Raising cut-offvalue of prostatespecific antigen (PSA) for biopsy in symptomatic men in India to reduce unnecessary biopsy Shalini Agnihotri, R.D. Mittai. R. Kapoor & Anil Mandhani Effects of gamma oryzanol supplementation on anthropometric measurements & muscular strength in healthy males following chronicresistance training Saghar Eslami, Norhaizan Mohd Esa, Seyed Mohammad Marandi, Gholamali Ghasemi & Sepehr Eslami Protective effects of glucose-6-phosphate dehydrogenase on neurotoxicity of aluminium applied into the CAl sector of rat hippocampus Marina D. Jovanovic, Ankica Jelenkovic, Ivana D. Stevanovic, Dubravko Bokonjic, Miodrag Colic, Natasa Petronijevic & Dauica B. Stanimirovic Roie of genetic & environment risk factors in theaetiology of colorectal cancer in Malaysia NurulHanis Ramzi. Jagdish Kaiir Chahil, SayMean Lye, Khamsigan Munretnam, KavithaItagi Sahadevappa, Sharmiia Velapasamy, Nikman Adli Nor Hashim, Soon Keat Cheah, Gerard Chin Chye Lim, Heselvnn Hussein, Mohd Roslan Haron. Livy Alex & Lian Wee Ler (iy) Contents Pages Impact of referral transport system on institutional deliveries in Haryana, India Shankar Prinja, Gursimer Jeet, Manmeet Kaur, Arun Kumar Aggarwal, Neha Manchanda & Rajesh Kumar ... 883 A study of Mycobacterium tuberculosis genotypic diversity & drug resistance mutations in Varanasi, north India Anamika Gupta, Savita Kulkami, Nalin Rastogi & Shampa Anupurba ... 892 Assessment of clinico-immunological profile of newly diagnosed HIV patients presenting to a teaching hospital of eastern India Saptarshi Bishnu, Dipanjan Bandyopadhyay, Samiran Samui, Indrani Das, Pradip Mondai, Pramit Ghosh, Deeptarka Roy & Sukanta Manna ... 903 Production of a compound against methicillin resistant Staphylococcus aureus(MRSA) fi:om Streptomyces rubrolavendulae ICN3 & its evaluation in zebrafish embryos Rajaretinam Rajesh Kannan, Appadurai Muthamil Iniyan & Samuel Gnana Prakash Vincent ... 913 Chironomid midges as allergens: evidence from two species fi-om West Bengal, Kolkata, India Soumi Nandi, Gautam Aditya, Indrani Chowdhury, Arijit Das & Goutam K Saha ... 921 Histopathological changes due to the effect of selenium in experimental cockerels S.A.A. Latheef, K Radhika G. Subramanyam 927 Effect of oxytocin injection to milching buffaloes on its content & stability in milk Raghu Pullakhandam, Ravindranadh Palika, Sudershan Rao Vemula, Kalpagam Polasa & Sesikeran Boindala ... 933 Circulation of hepatitis A genotype IIIA virus in paediatric patients in central India P. V. Barde, M,K Shukla, Ruchi Pathak, B.K Kori & P.K Bharti 94O Student IJMR Antimicrobial resistance pattern in Escherichia coli causing urinary tract infection among inpatients Niranjan V. & Malini A. 943 Correspondences Low rate of seropositivity(IgG) to mumps component in MMR vaccinees in Chennai, south India Jeevan Malaiyan,. Thatchayini Duraipandian, Aparna Warrier & Thangam Menon 949 Can Parvovirus B19 infection be naturally oncolytic: clinical findings raise such a possibility in leukaemic children Janak Kishore & Divya Kishore 952 Evaluation of the effectiveness of diagnostic & management decision by teleophthalmology for retinal diseases Aditi Gupta, Rajiv Raman & Tarun Sharma ^ 954 Authors' response S.C. Gupta, Subodh Kumar Sinha & Abhishek Dagar 955 Does serum vitamin-D predict insulin resistance in individuals with prediabetes? Sunil Kumar Raina 95^ Authors' response Deep Dutta, Indira Maisnam, Ankit Shrivastava, Anirban Sinha, Sujoy Ghosh, Pradip Mukhopadhyay. Satinath Mukhopadhyay & Subhankar Chowdhury 957 Contents Insulin resistance & vitamin-D levels in prediabetics Mehmet Agilli, Ibrahim Aydin & Fevzi NuriAydin Authors' response Deep Dutta. Indira Maisnam, AnkitShrivastava, Anirban Sinha, Sujoy Ghosh, Pradip Mukhopadhyay, Satinath Mukhopadhyay & Siibhankar Chowdhury Calculation error in estimating low HDL in women RS. Reddy Authors' response K.R. Thankappan, Bela Shah, Prashant Mathur, PS. Sarma, G. Srinivas, G.K. Mini Meena Daivadanam, Bijii Soman & Ramachandran S. Vasan CJinical Images Gollop-Wolfgang syndrome Naresh Dhanakodi & Siijit Kumar Tripathy Arc ofRiolan Sureka Binit & Mahesh Kumar Mittal , Book Reviews WHO Expert Committee on Drug Dependence Body composition and aging Books Received Some Forthcoming Scientific Events Guidelines for Contributors ^ •h-V- Indian J Med Res 140, July 2014, pp 1-156 Contents Editorial Pages Viral hepatitis eradication in India by 2080 - gaps, challenges & targets Manoj Kumar & Shiv K. Sarin 1 Commentaries How to prevent early mortalitydue to spinal cord injuries? New evidence 8l update Ellen Merete Hagen •f.:. v:;. Long term bisphosphonate therapy& atypical femoral fractures: A word of caution Sagili Vijaya Bhaskar Reddy Viewpoint Holobionts: emerging strategy for interventions against infectious diseases, metabolic disorders & cancer Yadvir Singh & Seyed E. Hasnain 11 Perspective Diabetic oncopathy - One moreyet another deadly diabetic complication! M. Balasubramanyam 15 Review Articles Epidemiology &social costs ofhaemophilia in India AnitaKar, SupriyaPhadnis, Siimedha Dharmarajan &Juki Nakade 19 Management ofnewborn infant bom to mother suffering from tuberculosis: Current recommendations & gaps in knowledge Hema Mittal, SaurabhiDas & MM.A. Faridi 32 Original Articles Mortality profile ofpatients with traumatic spinal injuries at a level Itrauma care centre in India S. Lalwani. V. Singh. V. Trikha. V. Sharma. S. Kumar. R. Bagla. D. Aggarwal & M.C. Misra 40 Predictors ofatypical femoral fractures during long term bisphosphonate therapy: A case series & review of literature Sanjay Kumar Bhadada, Subbiah Sridhar, Jeyaram Muthukrishmm, Ambrish Mithal, Dinesh C. Sharma, Anil Bhansali & Vandana Dhiman 46 Molecular evaluation of a novel missense mutation & an insertional truncating mutation in SUMFl gene Udhaya H. Kotecha. Sireesha Movva. Deepak Sharma. Jyotsna Verma, Rama Dua Puri i Ishwar Chancier Verma 55 Interleukin-6 (JL-6)-597 A/G (rsl 800797) &-174 G/C (rsl 800795) gene polymorphisms in type 2diabetes Madhukar Saxena. C. G. Agrawal. Neena Srivastava Monisha Banerjee 60 Expression ofgalectin-3 in gastric adenocarcinoma Th' Simao Gomes. Celma Tizuko Fujiyama Oshima, Nora Manoukian Forones, FliZoe OHveira Lima ^ Daniel Araki Ribeiro 69 Prevalencer. 1 ofr systemic COro-morbiditiesinu in patients with various grades••oft-•diabeticw- retinopathy P d^ Venkatesh. Sapna Tibrewal, Dipankar Bhowmik, Manjari Tripathi, SivaSramanian RamakrL-ihnan. Naginder Vashisf, Rajpal Vohra <& Satpal Garg 77 Level of suboptimal adherence to first line antiretroviral treatment &its determinants among HIV positive pe P Chauhan. Achhelal Pasi, Ragini Kulkarni. Nithya Sunil, Damodar Bachani, Beena Josni. Ranjit Mankeshwar &ART Adherence Sludy Group • ' • '•-/ -•'i-'' ' * Jr (iv) Contents Pages Grass pea consumption & present scenario ofneurolathyrism in Maharashtra State of India Arjun L. Khandare, J.JBabu, M. Ankulu, N Aparrta, AmolShirfule & G. Shankar Rao 96 Mosquito larvicidal potential of four common medicinalplants of India Anjali Rawani, Amtpam Ghosh & Goutam Chandra 102 Dipyrone & 2,5-dimethylcelecoxib suppress Th2-related chemokine production in monocyte Jeng-Chuan Shiang, Ren-Long Jan, Ming-Kai Tsai, Chong-Chao Hsieh, Hsuan-Fu Kuo, Chang-HungKuo, San-Nan Yang, Ming-Tii Huang, Li-ChenChen& Chih-Hsing Hung 109 a.. Drugresistance of Mycobacterium tuberculosis isolates from tuberculosis lymphadenitis patients in Ethiopia Fantahun Biadglegne, BelayTessema, Ulrich Sack&Arne C. Rodloff 116 Role of '^C methacetin breath test for non invasive staging of liver fibrosis in patients with chronic hepatitis C Carmen Fierbinteanu-Braticevici, Raluca Papacocea, Laura Tribus & Baicus Cristian 123 Antibacterial activityof three newly-synthesized chalcones & synergism withantibiotics against clinical isolates of methicillin-resistant Staphylococcus aureus Dragana D. Bozic, Marina Milenkovic, BrankaIvkovic &Ivana Cirkovic 130 Correspondences Riskfactors of pulmonary tuberculosis in teagarden communities ofAssam, India P.K. Chelleng, K. Rekha Devi, Debasish Borborb, M. Chetia, Avinash Saikia, Jagadish Mahanta & Kanwar Narain 138 Chronic inflammatory arthritis with persisting bony erosions in patients following chikungunya infection Itta Krishna Chaaithanya, NagarajanMuruganandam, Uppoor Raghuraj, Attayur Purushottaman Sugunan, Reesu Rajesh, MaileAnwesh, Subhodh Kumar Rai & Paluru Vijayachari 142 HIV prevention programmes & new interventions for truckers in India Divya Nair, Anindo Majumdar, Sitanshu Sekhar Kar&Ganesh Kumar S. 146 Authors' response Prem Kumar S.G., G. Anil Kumar, Ramesh Poluru, John A. Schneider, LalitDandona. Lakshmi Vemu, T Sudha, Kenneth H. Mayer & Rakhi Dandona 147 Selfweighing & non-probability samples Sunil Kumar Raina 149 Authors' response Rama Walia, Anil Bhansali, Muthuswamy Ravikiran, PadalaRavikumar, Sanjay K. Bhadada, G. Shanmugasundar, Pinaki Dutta & Naresh Sachdeva 150 Clinical Images Obturator hernia; a rare cause ofacute small bowel obstruction Shiue-Wei Lai & Tzu-Chuan Huang 151 Vascular ring with a Kommerell's diverticulum: Neonatal presentation with oesophageal symptoms Venkatraman S. Bhat & Vimal Raj 152 Book Reviews Hepatitis C in renal disease, hemodialysis and transplantation 154 Probiotic bacteria and their effect on human health and well-being 155 Some Fortlicoming Scientific Events 156 Guidelines for Contributors (V) I k-C^zsw.—.r-.r :.V-> j*- "'••.V'-v Indian J Med Res 140,August 2014, pp 157-326 Contents Editorials Violence against women in India: Comprehensive care for survivors Vijaykumar Harbishettar & Suresh Bada Math Liver biopsy interpretation & the regression ofhepatitis B virus related cirrhosis Fabio Grizzi & Valeer J. Desmet Commentaries Clobazam; The phoenix drug (from the very old to the brand new) Carlos A. M. Guerreiro Pneumococcal disease in India: The dilemma continues Joseph L. Mathew & Sunit Singhi Perspective Relationship ofhousehold air pollution from solid fuel combustion with tuberculosis? S.K. Jindal Special Report Establishment of BiosafetyLevel-3 (BSL-3) laboratory: Important criteriato considerwhile designing, constructing, commissioning & operating the facility in Indian setting , Devendra T. Momya, Pragya D. Yadav, Triparna Dutta Majumdar, Devendra S. Chauhan & Vishwa Mohan Katoch Review Article Health behaviours & problems among young people in India: Cause for concern & call for action Singh Sunitha & Gopalkrishna Giirumj Original Articles Effect ofclobazam as add-on antiepileptic drug in patients with epilepsy Rupa Joshi, Manjari Tripathi, Pooja Gupta & Yogendra Kumar Gupta Nasopharyngeal carriage, antibiogram & serotype distribution ofStreptococcus pneumoniae among healthy under five children K.L Ravi Kumar, Vandana Ashok, Feroze Ganaie & A.C. Ramesh Novel mutations in PRG4 gene in two Indian families with camptodactyly-arthropathy- coxa vara- pericarditis (CACP) syndrome Rajashree S. Nandagopalan, Shubha R. Phadke, Ashwin B. Dalai & Prajnya Ranganath Intra-articular injection ofdexketoprofen in rat knee joint: Histopathologic assessment ofcartilage & synovium Aycan Guner Ekici, OnatAkyol, Murat Ekici, Tolga Sitilci, Hakan Topacoglu & Emine Ozyuvaci Alpha thalassaemia in tribal communities ofcoastal Maharashtra, India Madhav G. Deo & Prakash V.Pawar Expression of interleukins 7 & 8 in peripheral blood mononuclear cells from patients with metabolic syndrome: A preliminary study M. Saidijam, A.S. Tootoonchi, M.T. Goodaizi, T Hassanzadeh, S.H. Borzuei, R. Yadegarazari & N. Shabab Antiviral drug profile of human influenza A & B viruses circulating in India: 2004-2011 V.A. Potdar, M.R. Dakhave, P.B. Kulkarni, S.A. Tikhe. S. Broor, P. Gimashekaran, M. Chawla-Sarkar, A. Abraham. D. Bishwas, K.N. Patil, A.A. Kadam, S.S. Kode. A.C. Mishra & M.S. Chadha Diagnostic efficacy of a real time-PCR assay for Chlamydia trachomatis infection in infertile women in north India Benu Dhawan. Jyoti Rawre. Arnab Ghosh, Neena Malhotra. Mir Muneer Ahmed. Vishnubhatla Sreenivas & Rama Chaudhiy . t' I » W;---. it? '1; -I- TiMMf- i" M"'"Y — (iv) Contents Pages Multiple drug resistantcarbapenemases producing Acinetobacter baitmannii isolates harbours multiple R-plasmids Rajagopalan Saranathan, Pagal Sudhakar, R. Uma Karthika, Santosh KumarSingh, P.Shashikala, Reba Kanungo & K. Prashanth 262 Clinicalprofile of HIV infectedpatientsattending a HIV referralclinic in Pune, India MeghaAntwal, Rohan Giirjar, Shweta Chidrawar, Jyoti Pawar, Sunil Gaikwad, Narayan Panchal, Varsha Kale, Madhitri Thakar, Anm Risbud & Srikanth Tripathy 271 Spatiotemporal distribution of dengue vectors & identificationof high risk zones in district Sonitpur, Assam, India MomiDas, Reji Gopalakrishnan, Dharmendra Kumar, Jyotsna Gayan, Indra Baruah, Vijay VeercS Prafulla Dutta 278 Laboratory evaluation of molluscicidal & mosquito larvicidal activities ofleaves ofSolariumnigrum L. AnjaliRawani, Amipam Ghosh & Goutam Chandra 285 Environmental management through sluice gated bed-dam; a revived strategy for the control of Anophelesfluviatilis breeding in streams S.S. Sahu, K. Gimasekaran & R Jambulingam ^ 296 Student IJMR Presenceof diabetes mellitus in the 'Dawoodi Bohra youth community' in Udaipur, Rajasthan S. Abbas, S. Goyal & T. Cornelius 302 Microbial contamination ofsoft contact lenses & accessories in asymptomatic contact lens users Deeksha V. Thakur & Ujjwala N. Gaikwad 307 Correspondences Trends of typhoid fever seropositivity over ten years in north India Tiihina Banerjee,BishwaNath Shukla, Joel Filgona, ShampaAnupurba & Malay Ranjan Sen 310 Durability of protectivefabrics against dengue VQCiov Aedes albopictus in northeasternIndia ReJi Gopalakrishnan, A.K. Chaurasia, Indra Baruah & Vijay Veer 314 Clinical Images Multiple epidermal cysts of scrotum Karthik K. Prasad & Manjunath R.D. 318 Childhood cerebral adrenoleukodystrophy Aliza Mittal & Kailash Chandra Aggarwal 319 Spontaneous pneumothorax in ataxia telangectasia Sudheer Chakravarthi & Manoj Kumar Goyal 321 Book Reviews ^ Brain, stroke and kidney 323 Nutrition and growth 324 Boole Received 325 Some Forthcoming Scientific Events 326 Guidelines for Contributors (V) : ^ V •' 'fi rr Indian J Med Res 140, September 2014, pp 327-468 Contents Editorials Pages World Heart Day - creating heart healthy environments Nakul Sinha, R.K. Saran & Mansoor Hasan ... 327 Healthy heart, happy life Zhibing Lu & Hong Jiang ... 330 Commentaries Traditional food & modem lifestyle: Impact of probiotics T. Bagchi _ 333 New directions for research into type 1 diabetes in India - An immimological perspective Ranjit Unnikrishnan & Viswanathan Mohan ... 335 Review Article Use of antibiotics in animal agriculture & emergence of methicillin-resistant Staphylococcus aureus(MRSA) clones: Need to assess the impact on public health PL Mehndiratta & P Bhalla ... 339 Original Articles Probiotic potential of lactic acid bacteria present in home made curd in southem India Ramadass Balamurugan, Aarthi Sophia Chandragunasekaran, Gowri Chellappan, Krithika Rajaram, Gayathri Ramamoorthi & Balakrishnan S. Ramakrishna ... 345 Clinical & immunological profile of newly diagnosed patients with youth onset diabetes mellitus D.K. Dhanwal, S. Agarwal, S. Garg & P Agarwal ... 355 CD3+,CD4+ & CD8+ tumour infiltrating lymphocytes(TILs) are predictors of favourable survival outcome in infiltrating ductal carcinoma of breast Ankita Singh Rathore, Sandeep Kumar, RituraJ Konwar, Annu Makker, M.PS. Negi & Madhu Mati Goel ... 361 Risk factor profile for non-communicable diseases among Mishing tribes in Assam, India: Results from a WHO STEPs survey Palash Jyoti Misra, G.K. Mini & K.R. Thankappan ... 370 Subclinical atherosclerosis in patients with rheumatoid arthritis by utilizing carotid intima-media thickness as a surrogate marker Alladi Mohan, Sujay Sada,B. Siddhartha Kumar, K. V.S. Sarma,B. Vijayalakshmi Devi, P. V.L.N. SrinivasaRao,D. Rajasekhar &D.T. Katyarmal ... 379 In vitro fertilization outcome in women with endometriosis & previous ovarian surgery Sonja Pop-Trajkovic, Vesna Kopitovic, Jasmina Popovic, Vladimir Antic, Dragana Radovic & Radomir Zivadinovic * ... 387 Comparative prognostic value of C-reactive protein & fibrinogen in patients . with coronary arteiy disease GJin Ndrepepa, Siegmund Braun, Tomohisa Tada, Lamin King, Salvatore Cassese, Massimiliano Fusaro, Dritan Keta,Adnan Kastrati & Roland Schmidt ... 392 Antibody screening & identification in the general patient population at a tertiary care hospital in New Delhi, India Raj Nath Makroo, Aakanksha Bhatia, Vikas Hegde, Mohit Chowdhry, Uday Kumar Thakur & Rosamma N.L ... 401 (iv) Contents Pages Application of real time polymerase chain reaction targeting kex 1 gene & its comparison with the conventional methods for rapid detection ofPneumocystisjirovecii in clinical specimens ManiRevathy, Kulandai Lily Therese, Radhakishnan Bagyalakshmi, Chokaliingam Chandrasekar, Suria Kumar &Hajib N. Madhavan ... 406 Clinical & biochemical profile of trichinellosis outbreak in north India RahulK. Sharma, N. Raghavendra, Smita Mohanty, BrijendraK. Tripathi, B. Gupta&Ankita Goel ... 414 Twin outbreak ofcholera in rural North Kamataka, India Shuchismita Dey, Mahantesh V. Parande, Aisha M. Parande, S.L. Lakkannavar, Poonam K. Rathore, B.G. Mantur, Sanjiva D. Kholkute & SubarnaRoy ... 420 Mosquitocidal Bacillus amyloliquefaciens: Dynamics of growth &. production of novel pupicidal biosurfactant 1. Geetha, R. Aruna & A.M. Manonmani ... 427 Correspondences Emergence of multi drug resistant bacteria in diabetic patients with lower limb wounds Wilbin Xavier, Mangalanandan T. Sukumaran, Ajit Kumar Varma, Harish Kumar & Gopi Chellan ... 435 Mosquito larvicidal properties of Mirabilisjalapa (Nyctaginaceae) againstAnopheles stephensi, Aedes aegypti & Culexquinquefasciatus (Diptera: Culicidae) M. Govindarajan, A. Ramya & R. Sivakumar ... 438 Clinical Images Osteosclerotic & osteolytic lesions in multiple myeloma Rapur Ram & Vishmibotla Siva Kumar ... 441 Myoepithelial cell carcinoma ofthe oral cavity AmishaA. Shah & YashwantIngle ... 443 Book Reviews Medical decision making ... 445 Genetic heterogeneity and human diseases ... 446 Policy Document Consensus & Evidence-based INOSA Guidelines 2014 (First edition) Surendra K. Sharma, Vishwa Mohan Katoch, Alladi Mohan, T Kadhiravan, A. Elavarasi, R. Ragesh, Neeraj Nischal, Prayas Sethi. D. Behera, Manvir Bhatia, A.G. Ghoshal, Dipti Gothi, Jyotsna Joshi, M.S. Kanwar, O.P Kharbanda, Suresh Kumar, PR. Mohapatra, B.N. Mallick, Ravindra Mehta, Rajendra Prasad, S.C. Sharma, KapilSikka, Sandeep Aggarwal, GarimaShukla, J.C. Suri, B. Vengamma, Ashoo Grover, V.K. Vijayan, N. Ramakrishnan, Rasik Gupta for Indian Initiative on Obstructive Sleep Apnoea (INOSA) Guidelines Working Group ... 449 Guidelines for Contributors • ... (v) •y.Ai. '. 'i •• - 's-l ; ' 1''' ' I •'9 It: •iiTiii >1 iriTi Indian J Med Res 140, October 2014, pp 469-578 Contents Editorials Schizophrenia - Enhancing hope with better care 8i research R. Thara The challenge of childhood cataractblindness Jagat Ram & AniruddhaAgarwal Commentaries HIV/AIDS in India - Indigenous evidence through operational research Gautam Ahlnwalia Early detection ofmulti-drug resistant tuberculosis in India using GenoType MTBDRplus assay &profile ofresistance mutations in Mycobacterium tuberculosis Sannan Singh Reference range of serum prostate-specific antigen levels inIndian men Rama Devi Mittal Review Article Vitamin D& endothelial function A. Alyami, MJ. Soares, J.L. Sherhff&J.C. Mamo Original Articles Determinants ofsurvival in adult HIV patients on antiretroviral therapy inEastern Uttar Pradesh: A prospective study Java Chakravarty, Narendra K. Tiwaiy. Shashi Ranjan Prasad, Saurabh Shukla, Anurag Tiwari Rabindra Nath Mishra & Shyam Sundar Detection ofmulti-dmg resistance &characterization ofmutations in Mycobacterium tuberculosis isolates from North-eastern States of India using GenoType MTBDRplus assay Ritu Singhal, Vithal Prasad Myneedu, Jyoti Arora, Niti Singh. Girish Chander Sah & Rohit Sarin Ahospital based study on reference range of serum prostate specific antigen levels Aditi Gupta, Deepa Gupta. Arun Raizada, Narmada Prasad Gupta, Rajiv Yadav, Kamini Vinayak & Vijay Tewah Double positive CD4-f-CD8+ Tcells: key suppressive role in the production of autoantibodies in systemic lupus eiythematosus Yongkang Wu. Bei Cai, Weihua Feng. Bin Yang. Zlmochun Huang, Oman Ziio &Lanlan Wang Effect ofextreme conditions ofAntarctica on human leukocyte antigen-G in Indian expeditioners K.P. Mishra. A.P. Yadav. YK. Sharma. Lilly Ganju & S.B. Sif?gh Role of leptin on the expressi.on of low density lipoprotein receptor NavalKishor Yadav. Albina Arjuman & Nimai C. Chandra Vitamin D levels in Indian children with intrathoracic Uiberculosis Deepchand Khandelwal, Nandita Gupta, Aparna Mukherjee. Rakesh Lodha. Varinder Smgh, Harleen M.S. Grewal. Shinjini Bhatnagar. Sarman Singh. S.K. Kabra & Delhi Pediatric TB Study Group Contents Pages Effect ofhouse spraying with lambdacyhalothrin 10 per cent capsule suspension (CS) formulation in comparison with 10per cent wettable powder(WP) againstmalaria vector in Malkangiri district, Odisha, India K. Gimasekaran, S.S. Sahii, T Vijayakumar, S. Siibramanian & P. Jamhulingam Detection ofNew Delhi metallo beta lactamase-1 (NDM-1) carbapenemase in Pseiidomonas aeniginosa in a single centre in southern India Mariappan Shanthi, UmaSekar, Anmagiri Kamalanathan & Balaraman Sekar Functional response analysis ofAnisops sardea (Hemiptera; Notonectidae) against Ciilexquinqiiefasciatus in laboratory condition Rajendra Prasad Mondal, Amipam Ghosh, Subhasis Bandyopadhyay & Goiitam Chandra Student IJMR Fungal profile offunguria cases at a tertiary care hospital in southern India SurumyP. Siilaiman, Rakesh Singh & Jharna Mandal Correspondences Efficacy of anti-pseudomonal antibiotics: Need to reconsider the empirical use of cefepime A. Kotwal, D. Biswas, B. Kakati, B. Thakuria & N. BhardwaJ Adverse drug reactions reporting culture in Pharmacovigilance Programme ofIndia Vivekanandan Kalaiselvan, ThotaPrasad, Akanksha Bisht, SurinderSingh & Gyanendra Nath Singh Areport on the presence of GES-5 extended spectrum beta-lactamase producing Pseiidomonas aeniginosa associated with urinary tract infection from north-east India Anand Prakash Mainya, Debarati Choiidbwy, Aniipam Das Tahikdar, Debadatta Dhar (Chanda), Atami Chah-avarty &Amitabha Bhallacharjee Cost calculations in health care Kanica Kaiishal Authors' response NJ. Gogtay A. Nagpal. A. Mallad, K. Pate/, S. J. Stimpson, A. Behir cS U.M. Thalte Clinical Images Cri-du-chat syndrome R. Nandhagopal & A. M. Udayakumar Brown-Sequard syndrome Upasana Ranga & Senthil Kumar Aiyappan Book Reviews ChronolherapcLitics for affective disorders; Aclinician's manual for light and wake therapy ' Drug - drug interactions for therapeutic biologies Some Forthcoming Scientific Events Guidelines for Contributors Indian J Med Res 140, November 2014, pp 579-700 Contents Editorial Pages Know the signs and symptoms of diabetes A. Ramachandran ... 579 Commentaries Probiotics, prebiotics & synbiotics in small intestinal bacterial oveigrowtfa: Opening up a new therapeutic horizon! Wei Chung Chen & Eamonn MM. Quigley ... 582 Role of matrix metalloproteinases in physiological processes & disease V.V. RaviKanth &D,NageshwarRedcfy ... 585 Review Article Genetic & epigenetic approach to human obesity K. Rajender Rao, Nirupama Lai &N.V. Giridharan ... 589 Original Articles Evaluating the efficacy of probiotic on treatment in patients with small intestinal bacterial overgrowth(SIBO) - A pilot study ► A.R. Khalighi, M.R. Khalighi, R. Behdani, J. Jamali, A. Khosravi, Sh. Kouhestani, H. Radmanesh, S. Esmaeelzadeh&N. Khalighi ... 604 Association of matrix metalloproteinase -7 (-18 iA/G) promoter polymorphism in chronic pancreatitis K. Sri Manjari, A. Jyothy, P. Shravan Kumar. B. Prabhakar, Pratibha Nallari & A. Venkateshwari ... 609 Relationship between promoter methylation & tissue expression of MGAfTgene in ovarian cancer Shilpa v., Rahul Bhagat, C.S. Premalata, Pallavi V.R., G. Ramesh & Lakshmi Krishnamoorthy ... 616 Renal cell carcinoma in India demonstrates early age of onset & a late stage of presentation Shalini Agnihotri. Jatinder Kumar, Manoj Jain, Rakesh Kapoor & Anil Mandhani ... 624 Propofol or sevoflurane anaesthesia does not affect hepatic integrity as assessed by ffie M30 & M65 cell death markers & liver enzymes Konstantinos Chondrogiannis, Emilia Hadziyannis & Argyro Fassoulaki ... 630 Internal consistency & validity of Indian Disability Evaluation and Assessment Scale (IDEAS) in patients with schizophrenia Sandeep Graver, Ruchita Shah, ParmanandKulhara & Rama Malhotra ... 637 Use of computerized tests to evaluate psychomotor performrmce in children with specific learning disabilities in comparison to normal children Santosh Tour, Sunil Karande, Akriti A. Saxena, Nithya J. Gogtay & Urmila M. Thatte ... 644 Nucleic acid amplification tests (NAATs) for gonorrhoea diagnosis in women: Experience of a tertiary care hospital in north India Seema Sood, Rachna Verma, Shazia Shaheen Mir, Madhav Agarwal, Neeta Singh, Hemanta Kumar Kar Vinod Kumar Sharma • ■ • 649 Estimation of vectorial capacity of Anopheles minimus Theobald & An. fluviatilis James (Diptera: Culicidae) in a malaria endemic area of Odisha State, India K. Gunasekaran, S.S. Sahu & P. Jambulingam — 653 r ' "...niLwe Indian (iv) Contents Pages A three year retrospective study on the increasing trend in seroprevalence ofdengue infection from southern Odisha, India Edito] Sanghamitra Padhi, Muktikesh Dash, Pritilata Panda, BanojiniPanda, Indrani Mohanty, Susmita Sahu & M.V. Narasimham Sphizc 660 R. Time dependent enhanced resistance against antibiotics & metal salts by planktonic & biofilm form ofAcinetobacter haemolyticus MMC 8 clinical isolate The cl Jo Sharvari Vijaykumar Gaidhani, Aartee Vishnu Raskar, Sharmishtha Poddar, Shriya Gosavi, Praveen Kishore Sahu, Karishma Rajendra Pardesi, Shobhana V. Bhide Comr & Balu Ananada Chopade 665 HIYU NDM-1 (New Delhi metallo beta lactamase-1) producing Gram-negative bacilli: G Emergence & cHnical implications Early BashirAhmadFomda, Asiya Khan & Danish Zahoor 672 assay Comparison of pulsed-field gel electrophoresis & repetitive sequence-based PGR methods Sc for molecular epidemiological studies ofEscherichia coli clinical isolates Refer" IIKwon Bae, Juwon Kim, Je Young Hannah Sun, Seok Hoon Jeong, Yong-Rok Kim, R. Kang-Kyun Wang & Kyungwon Lee 679 Revie Correspondences Vitaff Serological diagnosis ofscrub typhus in patients attending a government hospital A at Vellore, Tamil Nadu Origi V. Rajagopal, M. Bhaskar, R. Renuka Devi & P. Rajkumar Deter 686 A pro Detection ofAmpC p-lactamases production in Acinetobacter species by inhibitor (disk) J. based & modified three dimensional (enzyme extraction) methods R E. Kumar, K. Usha, A. Chaudhury, B. V. Ramana &D.V.R. Sai Gopal 688 Detec Astudy on surgical site infections after trauma surgeries in atertiary care hospital in north India tuber Nonika Rajkumari, Kumkum Sharma, Purva Mathur, Subodh Kumar &Amit Gupta 691 R Clinical Images C Huge neurofibroma ofthe scalp Ahof MuhammedEren ^im§ek & Ramazan Kahveci A 695 Intranasal ectopic tooth Wen-Sen Lai & Jih-Chin Lee Dout 696 autoa Book Reviews } Inflammation in psychiatry 697 Effec Clinical recovery from CNS damage 698 / Book Received 699 Role Some Forthcoming Scientific Events 700 P Errata 700 Vitar Guidelines for Contributors L (V) } I .-1/ . - .1 . H- * •'v' ' • Indian J Med Res 140, December 2014, pp 701-822 Contents Editorials Long term impact ofantiretroviral therapy - Can we end HIV epidemic, the goal beyond 2015 N. Kumarasamy & R. Pendse After 3 decades ofpaediatric HIV/AIDS - Where do we stand? M M. Lala & R. H. Merchant Viewpoint Addressing tobacco use & dependence in primary care: A priority for tobacco control in the country Rajmohan Panda Commentanes Spectrum ofHashimoto's thyroiditis: Clinical, biochemical & cytomorphologic profile Debmalya Sanyal An insight into the understanding of5-HTR2A variants leading to schizophrenia Kusuma Lingaiah & Nallur B. Ramachandra Review Article Current concepts on magnetic resonance imaging (MRI) perfusion-diffusion assessment in acute ischaemic stroke: a review & an update for the clinicians Ernesto Roldan-Valadez & Mariana Lopez-Mejia Original Articles Clinical, biochemical & cytomorphologic study on Hashimoto's thyroiditis Tina Thomas, Snja Sreedharan, Urmila N. Khadilkar, Deviprasad D, M. Panduranga Kamath, Kiran M. Bhojwani S: Arathi Alva 5-Hydroxytryptamine(serotonin) 2A receptorgene polymorphism is associatedwith schizophrenia Siibash Padmajeya Sujitha, Asha Nair, Moinak Banerjee, Srinivasan Lakshmanan, Sampth Harshavaradhan, Soosiah Gunasekaran &Anilkiimar Gopinothan Expression profile of mitrogen-activated protein kinase (MAPK) signaling genes in the skeletal muscle & liver of rat with type 2 diabetes: Role in disease pathology Xiaoli Tang, Libin Deng, Hiiangid Xiong, GiiilinLi, Jiari Lin, Shuangmei Liu, Jinyan Xie, Jun Liu, Fanjun Kong, Guihua Tu, Haiying Peng <& Shangdong Liang Hypobaric hypoxia-mediated protein expression in plasma of susceptible & tolerant rats Santosh Kumar, Priyanka Sharma, Anju Bansal, Prakash C. Sharma & Kamal K. Aggarwal Antigen sequence typing ofouter membrane protein (fetA) gtne ofNeisseria meningitidis serogroup A from Delhi & adjoining areas S. Dwivedi, B.K. Das, A. Kapil, S. Sood, R. Chaudhry, S. Gupta, M. Deb, D. Nair & S. Aneja MALDI-TOF mass spectrometry proteomic based identification ofclinical bacterial isolates Ashutosh Panda. Sravya Kurapati, Jyotish C. Samantaray, Alagiri Srinivasan & Shehla Khali! Characterization of Shiga-toxigenic Escherichia coli isolated from cases ofdiarrhoea & haemolytic uremic syndrome in north India Ajay Kumar. Neelam Taneja, Bhavneet Bharti & Meera Sharma m (iv) Contents Pages Correspondences Seroprevalence ofcoxiellosis (Q fever) in sheep & goat in Puducherry & neighbouring TamilNadu Selvaraj Stephen, Balakrishnan Sangeetha & PrabakharX. Antony 785 Need for & use ofguidelines for reporting qualitative research N.J. Gogtay, U.M. Thatte, S. Thaker & S. Deshpande 788 Authors' response N.N. Mishra, Triptish Bhatia, Nandini Kumar, Vishwajit L. Nimogaonkar Lisa Parker & Smita N. Deshpande 789 Avoiding contamination in randomized controlled trial Kanica Kaushal 790 Authors' response Johnson Pradeep R., Anton Isaacs, Deepthi Shanhag, Sumithra Selvan & Krishnamachari Srinivasan 791 Clinical Images Classical eschar in scrub typhus Prashant Bafna & Tamitarasu Kadhiravan 792 Oculomotor nerve palsy in dengue encephalitis - a rare presentation Nirendra Mohan Biswas &. Soiiren Pal 793 Book Reviews Nutrition and growth 795 The psychiatric interview: Evaluation and diagnosis 796 Some Forthcoming Scientific Events 798 Panel of Reviewers (2014) 799 'iMti Guidelines for Contributors (v) .'•J • ••'••"• • '•• 'k