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.X' Volume 139 Number 1 January 2014 ISSN: 0971-5916 Estd : 1913 Submit online: littp://\v>v>v.journalonweb.coiii/ijnir THE INDIAN JOURNAL OF MEDICAL RESEARCH nevXS INDIAN COUNCIL OF MEDICAL RESEARCH NEW DELHI www.ijmp.org.ip Indian J Med Res 139, January 2014, pp 1-184 Contents Editorial Alzheimer's disease prevention & acetyl salicylic acid: a believable story Massimiliano Pomponi & Massimo F.L. Pomponi Commentaries Approach to the diagnosis ofdevelopmental delay - The changing scenario Neerja Gupta & Madhulika Kabra India can do more about intestinal worm infections Nilanthi de Silva Review Articles Role ofgut pathogens in development ofinitable bowel syndrome Madhiisudan Grover Probiotic foods: Can their increasing use in India ameliorate the burden of chronic lifestyle disorders? Neerja Hajela, G. Balakrish Nair, B.S. Ramah'ishna & N.K. Ganguly Distribution ofgenetic polymorphisms ofgenes encoding drug metabolizing enzymes & drug transporters - a review with Indian perspective Gurusamy Umamaheswaran, Dhakchinamoorthi Krishna Kumar & Chandrasekaran Adithan Original Articles Clinical utility ofmultiplex ligation-dependent probe amplification technique in identification ofaetiology of unexplained mental retardation: A study in 203 Indian patients Vy'ay R. Boggula, Anju Shukla, Siimita Danda, Sankar V. Hariharan, Sheela Nampoothiri, Rashmi Kumar <& Shubha R. Phadke Prevalence & risk factors for soil transmitted helminth infection among school children in south India Deepthi Kattula, Rajiv Sarkar, Sitara Swarna Rao Ajjampur, Shantidani Minz, Bruno Levecke, Jayaprakash Muliyil & Gagandeep Kang Association between obstetric complications & previous pregnancy outcomes with current pregnancy outcomes in Uttar Pradesh, India Deepti Singh, Srinivas Goli & Sulabha Parsuraman Endophthalmitis patients seen in a tertiaiy eye care centre in Odisha: A clinico-microbiological analysis Savitri Sharma, Tapas R. Padhi, Sownyava Basu, Sarita Kar, Arvind Roy & Taraprasad Das Prevalence ofGraves' ophthalmopathy in patients with Graves' Jisease presenting to a referral centre in north India Sagiii Vijaya Bhaskar Reddy, Ami Jain, Subhash B. Yadav, Kimnidini Sharma & EeshBhalia Molecular genotyping ofABO blood groups in some population groups from India Sabita Ray, Ajit C. Gorakshakar, K. Vasantha, Anita Nadkarni, Yazdi Italia & Kanjaksha Ghosh Efficacy & safety ofcontinuous erythropoietin receptor activator (CERA) in treating renal anaemia in diabetic patients with chronic kidney disease not on dialysis Sameer G. Vankar. Pinaki Dutta, H.S. Kohli & Anil Bhansali (iv) Contents Pages Validity of SW982 synovia! cell line for studying the drugs against rheumatoid arthritis in fluvastatin-induced apoptosis signaling model Jae-Ho Chang, Kyu-Jae Lee, Soo-Ki Kim, Dae-Hyun Yoo & Tae-Young Kang ... 117 Expressional regulation of genes linked to immunity & programmed development in human early placenta! villi M.A. Khan, S. Manna, N. Malhotra, J. Sengupta & D. Ghosh 125 Bio-medical waste management: situational analysis & predictors of performances in 25 districts across 20 Indian States INCLEN Program Evaluation Network (IPEN)study group. New Delhi, India ... 141 Clinical profile & predictors of poor outcome of adult HlV-tuberculosis patients in a tertiary care centre in north India Surendra K. Sharma, Manish Soneja, K.T Prasad & Sanjay Ranjan 154 Polymerase chain reaction targeting insertion sequence for the diagnosis of extrapulmonary tuberculosis V. Makeshkumar, Radha Madhavan & Sujatha Narayanan Survival of diumally sub periodic Wuchereria bancrofti in Downsiomyia nivea (Diptera: Culicidae): a density dependent factor from Andaman & Nicobar Islands A.N. Shriram, K. Krishnamoorthy & P. Vanamail jgy Student IJ?i1R Assessment of stress & related albuminuria in caregivers of severe mentally ill persons Anirban Dalui, Prathama Guha, Angshuman De, Sandip Chakraborty & Indranil Chakraborty 174 Correspondence The relationship between the use of fluconazole & the incidence of fluconazole-resistant Candida species Chia-Chang Kuo & Chien-Ming Chao jyg Authors' response J.K. Oberoi, C. Wattal, N. Goel, R. Raveendran, S. Datta & K. Prasad 278 Clinical Images Stewart-Treves syndrome Marek Stcinczyk & MagdaJena Gewartowska j A case of pycnodysostosis presented with pathological femoral shaft fracture Shailendra Singh & Balaji Sambandam j Book Reviews The evolving threat of antimicrobial resistance: Options for action jg2 WHO qualityRights tool kit: Assessing and improving quality and human rights in mental health and social care facilities jg^ Book Received ^g^ Guidelines for Contributors , . (v) Indian J Med Res 139, February 2014, pp 185-332 Contents Editorial Pages Debunk the myths: Oncologic misconceptions Jaydip Biswas 185 Commentaries Depression in primarycare: challenges & controversies Ajit Avasthi & Abhishek Ghosh 188 Ethical challenges 8c dilemmasfor medicalhealth professionals doing psychiatric research Manjulika Vaz <& K. Srinivasan 191 Review Articles Opportunistic invasive fungal infections: diagnosis & clinical management • Parisa Badiee & Zahra Hashemizadeh 195 Antimalarial drug policy in India: Past, present & future AnupkumarR. Anvikar, UshaArora, GS. Sonal, Neelima Mishra, Bharatendu Shahi, DeepaliSavargaonkar, Navin Kumar, Naman K. Shah &Neena Valecha 205 Breast cancer painmanagement -A review of current & novel therapies AanchalSatija, SyedMehmood Ahmed, RahulGupta, ArifAhmed, Shiv Pratap Singh Rana, Suraj Pal Singh, Seema Mishra & Sushma Bhatnagar 216 Special Reports 1 ICMRprogramme onAntibiotic Stewardship, Prevention of Infection & Control (ASPIC) 't SujithJ. Chandy, Joy SarojiniMichael, Balaji Veeraraghavan, O.C. Abraham, Sagar S. Bachhav & Nilima A. Kshirsagar 226 Perceptions of State Government stakeholders & researchers regarding public health research priorities in India:An exploratory survey Prabhdeep Kaur, Grace A. Chitra, Sanjay M. Mehendale& Vishwa M. Katoch 231 Original Articles Enhanced careby community health workers in improving treatment adherence to antidepressant medication in rural women with major depression Johnson Pradeep, Anton Isaacs, DeepthiShanbag, SumithraSelvan iSc Krishnamachari Srinivasan 236 Knowledge &attitudes of mental health professionals regarding psychiatric research N.N. Mishra, Triptish Bhatia, Nandini Kumar, Vishwajit L. Nimgaonkar, LisaS. Parker cfe Smita N. Deshpande 246 High prevalence ofcardiovascular risk factors inAsian Indians^ Acommunity survey - Chandigarh Urban Diabetes Study (CUDS) Rama Walia, Anil Bhansali, Muthuswamy Ravikiran, PadalaRavikumar, Sanjay K. Bhadada, G. Shanmugasundar, Pinaki Dutta & NareshSachdeva 252 A single hospital study onportal vein thrombosis in cirrhotic patients - clinical characteristics & risk factors Huisong Chen, Goolab Trilok, Fei Wang, Xiaolong Qi, Junjie Xiao &Changqing Yang 260 Early evaluation ofmagnetic resonance imaging guided focused ultrasound sonication in the treatment ofuterine fibroids Y. Himabindu, M. Sriharibabu, Vinay Nyapathy &Anindita Mishra 267 'v- f<- -'i •.vj Contents a-Adducin gene G614Tpolymorphisms in essential hypertension patientswith high low density lipoprotein (LDL) levels Lifang Wang, BinZheng, Hongguang Zhao, Peng Du, Aihua Sun, Kouzhen Hua c& Yuyu Gao Effect ofgender, biochemical parameters & parathyroid surgery on gastrointestinal manifestations ofsymptomatic primary hyperparathyroidism Viral N. Shah, Sanjay KumarBhadada, AnilBhansali, A. Behera,Anish Bhattacharya, Uma Nahar, Deepak Bhasin &. Bhavin Vadera Effect of public-private partnership in treatment of sexually transmitted infections among female sex workers in Andhra Pradesh, India Suresh Babu Kokku, Bidhubhusan Mahapatra, Saroj Tucker, NiranjanSaggurti& Parimi Prabhakar Response ofmalaria vectors to conventional insecticides in the southern districts ofOdisha State, India S.S. Sahu, K. Gunasekaran, H.K. Raju, P. Vanamail, M.M. Pradhan & P. Jambulingam Lymph nodes cytology in HIV seropositive cases with haematological alterations Neelima Tirumalasetti & P. Prema Latha Role of 72 kDa protein ofLeptospira interrogans asa diagnostic marker inacute leptospirosis M. Riazi, F.Z. Zainul, A.R. Bahaman, F. Amran & A. Khalilpour Correspondences High frequency of young age rectal cancer in a tertiary care centre of southernAssam, North East India Ruhina Shirin Laskar, Fazlur Rahman Talukdar, Rosy Mondal, Ravi Kannan t&. Sankar Kumar Ghosh In vitro evaluation ofantibiotics for methicillin-resistant Staphylococcus aureus from north India AbhishekMewara, Vikas Gautam, Harsimran Kaur & Pallab Ray Need to revisit vitamin A supplementation programme in India J.K Raman & Deepika Nayar Chaudhery Authors' response H.P.S. Sachdev & Umesh Kapil Clinical Images A rare type ofpartial anomalous pulmonary venous return in late diagnosed patients AH Kemal Sivrioglu & Giiner Sonmez Exogenous ochronosis Avninder Singh & V Ramesh Book Reviews WHO Study Group on Tobacco Product Regulation WHO Expert Committee on Leprosy Some Forthcoming Scientifc Event Form IV Guidelines for Contributors WW:'- Indian J Med Res 139, March 2014, pp 333-480 Contents Editorial Pages Tuberculosis in India - Can we ensure a test, treatment & cure for all? Soumya Swaminathan ... 333 Commentaries Alielic variability in PSA & AR genes: A novel biomarker on the horizon for carcinoma prostate RN. Dogra ... 337 Probiotics for diarrhoea SusameHempel ... 339 Review Articles Migraine & paediatric obesity: a plausible link? SaritRavid ... 343 Cytogenomics of hexavalent chromium (Cr^)exposed cells: A comprehensive review Akanksha Nigam,