November 13, 2014

Francis S. Collins, M.D., Ph.D. Director National Institutes of Health 9000 Rockville Pike Bethesda, MD 20892

Dear Dr. Collins:

We, the undersigned aging and Alzheimer’s disease researchers, educators and clinicians strongly urge you to include an additional $500 million in the FY 2016 National Institutes of Health (NIH) Budget to support aging research. We believe that this funding is the minimum essential to sustain research needed to make progress in attacking the chronic diseases that are driving significant increases in our national healthcare costs. The institutes that make up the NIH, in particular the National institute on Aging (NIA), lead national scientific efforts to understand the nature of aging in order to promote the health and well-being of older adults, whose numbers are projected to increase dramatically in the coming years due to increased life expectancy and the aging of a baby boom generation.. According to results from the 2010 Decennial Census, “the U.S. population 65 and older is now the largest in terms of size and percent of the population.” Further, the U.S. Census Bureau currently estimates that the number of people age 65 and older is 13.7 percent of the population and will rise to 88.5 million or 20 percent of the population by 2050. Those 85 and older will reach 19 million by 2050, a three-fold increase from just three years ago.

Increased investment in preventing, treating or curing chronic diseases of aging is perhaps the single most effective strategy in reducing national spending on health care. According to the Centers for Medicare & Medicaid Services, in 2011 approximately 23 percent of beneficiaries had 4 or 5 multiple chronic diseases associated with aging. Medicare spends an average of $9,738 per beneficiary per year. Beneficiaries with 4 or more chronic conditions have Medicare spending higher than this average, as much as $13,000 per year. Unprecedented increases in age-related chronic diseases as the population ages are one reason the Congressional Budget Office projects that total spending on healthcare will rise to 25 percent of the U.S. GDP by 2025. Simply put, our nation does not have the luxury of time to wait to address the health research needs of this population.

Alzheimer’s disease and related dementias and the tremendous toll it places on caregivers are a dramatic example of the crisis ahead. The NIA reports that as many as 5.1 million Americans over 65 are today dying with Alzheimer's disease and the numbers of Americans that will die of this disease are projected to increase dramatically in the coming years. It is estimated that over 10 million baby boomers will develop Alzheimer’s in addition to today’s victims. Alzheimer’s disease will also cause physical and emotional impairments on more and more families and caregivers. The growing numbers of Alzheimer’s victims and the rapidly-rising costs associated with the disease will put a heavy economic burden on families, businesses and government. Estimates are that the costs of Alzheimer’s care will amount to $2 trillion by 2020. In stark contrast to the increasing costs of healthcare for the aging population, we as a nation are making a miniscule, and declining, investment in the prevention, treatment or cure of aging conditions. We appreciate that despite a budget shortfall, NIH dedicated an additional $100 million for Alzheimer’s disease research with support from the Administration last year. This funding has been allocated to many worth Alzheimer’s disease research programs, but as you know there are many recommendations that grew out of the NIH’s 2012 Alzheimer’s Disease Research Summit that still have not been supported to meet the goal of finding effective therapies by 2025 set out in our National Plan to Address Alzheimer’s Disease. As you know, there is also an upcoming Alzheimer’s Disease Research Summit in February 2015 that will no doubt result in additional research recommendations. Francis S. Collins, M.D., Ph.D. November 13, 2014

In addition to increased opportunities to make advances against Alzheimer’s disease, NIH is also poised to accelerate other scientific discoveries that we as a nation are counting on. Twenty of the 27 institutes and centers at the NIH are now working more closely under the banner of the Trans-NIH Geroscience Interest Group (GSIG) to understand basic cellular and molecular underpinnings of aging as a principal risk factor for chronic disease and to explore common mechanisms governing relationships between aging and chronic disease. Activities organized by the GSIG like regular meetings, quarterly seminars and the recommendations from the 2013 Advances in Geroscience Summit have identified new pathways for research collaboration. Research that can be translated quickly into effective prevention and efficient health care will reduce the burden of a “Silver Tsunami” of age-associated chronic diseases. Breakthroughs from NIH research can lead to treatments and public health interventions that could delay the onset or slow the progression of costly conditions such as heart disease, stroke, diabetes, bone fractures, age-related blindness, and neurological diseases. Such advances could save trillions of dollars by the middle of the current century.

As you develop a proposed FY 2016 NIH budget that includes cost-effective health research for all Americans, we look forward to working with you. Thank you for considering our views, and please do not hesitate to contact Sue Peschin, Chair, Friends of the NIA, at (202) 688-1246 or email [email protected] if you have any questions or would like additional information.

Sincerely,

Katherine Abbott Anshu Agrawal Research Assistant Professor Associate Adjunct Professor University of Pennsylvania University of California Irvine

Carmela R. Abraham, Ph.D. Paul Aisen, M.D. Professor, Department of Biochemistry Professor of Neurosciences Boston University School of Medicine University of California, San Diego

Muhammed K. Absar, M.D. Tom Ala, M.D. Assistant Clinical Professor Center for Alzheimer's Disease and Related Disorders Tufts University Medical School Southern Illinois University School of Medicine Diplomate, Behavioral Neurology & Neuropsychiatry Medical Director, Geriatric Neuropsychiatry Melissa Alldred, PhD Metro West Medical Center Research Assistant Professor Dept of Psychiatry, NYU Olga Achildi, M.D. Langone Medical Center Department of Psychiatry Temple University Hospital Richard M. Allman, M.D. Parrish Endowed Professor of Medicine ActivistsAgainstAlzheimer's Director, Center for Aging & Division of Gerontology, Geriatrics & Palliative Care AfricanAmericansAgainstAlzheimer's Birmingham/Atlanta VA Geriatric Research Education & Clinical Center Eugene Agichtein Assistant Professor Emory University

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Francis S. Collins, M.D., Ph.D. November 13, 2014 Dr. Yair Argon Allan A. Anderson, M.D. Professor, Dept. Pathology and Lab Medicine Medical Director, The University of Pennsylvania Samuel and Alexia Bratton Memory Clinic Assistant Professor John Hopkins University Csilla Ari, Ph.D. Current President, American Association for Geriatric Postdoctoral scholar Psychiatry Byrd Alzheimer Institute, USF

Julie K. Andersen, Ph.D. Robert Arking Professor Professor of Biological Sciences The Buck Institute for Age Research Wayne State University

Martha S. Anderson, DNP, CNS, FNGNA Peter Armour Associate Professor Manager, Department of Epidemiology & Biostatistics Jefferson College of Health Sciences University of California at San Francisco

Katrin Andreasson Lisette Arnaud Associate Professor of Neurology Doctor Stanford University Institute for Basic research in Development Disabilities

Mary Ann Fricker Steven E. Arnold, M.D. Retired MSN,RN Professor of Psychiatry and Neurology Director, Penn Memory Center Liana Apostolova, M.D. MSCR Associate Director, Institute on Aging Assistant Professor of Neurology University of Pennsylvania UCLA Mary S. Easton Center for Alzheimer's Disease Research J Wesson Ashford M.D., Ph.D. Clinical Professor of Psychiatry and Behavioral Sciences James C. Appleby, RPh, MPH (affiliated) Executive Director & CEO Stanford University The Gerontological Society of America Sanjay Asthana, M.D. Kimberly D. Acquaviva, Ph.D., M.S.W. ADRC Director, University of Wisconsin School of Associate Dean for Faculty Affairs; Associate Professor Medicine and Public Health The George Washington University School of Nursing Ayodeji Asuni Maria P. Aranda, Ph.D., L.C.S.W. Research Assistant Professor Associate Professor, School of Social Work New York University University of Southern California Craig Atwood, Ph.D. Jill Ardila Associate Professor of Medicine Assistant Director for Clinical Research University of Wisonsin-Madison School of Medicine and USF Health Byrd Alzheimer's Institute Public Health

Christine Arenson, MD Pavan K. Auluck, M.D., Ph.D. Professor and Research Fellow Interim Chair Massachusetts General Hospital and the Whitehead Department of Family and Community Medicine Institute for Biomedical Research

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Francis S. Collins, M.D., Ph.D. November 13, 2014 Steven N. Austad, Ph.D. Joseph Baur, Ph.D. Professor, Department of Cellular and Structural Biology Assistant Professor of Physiology University of Texas Health Science Center University of Pennsylvania School of Medicine Barshop Institute for Longevity & Aging Studies Peter Bayley, Ph.D. Bobbie Ann Austin, PhD Assistant Professor of Psychiatry and Behavioral Assistant Director of Science Policy & Programs Sciences (affiliated) The Association for Research in Vision and Stanford University Opathamology Hillary Beach Suan Averbach Thomas Jefferson University Senior Public Administrative Analyst, Department of Department of Family and Community Medicine Epidemiology and Biostatistics Program Assistant, EPaD GEC Grant University of California at San Francisco Robert E. Becker M.D., C.M. Jason Bailey President Doctoral Candidate Aristea Translational Medicine Corporation Indiana University School of Medicine Walter K. Beech James R. Bamburg Biological Lab Science Technician Professor Emeritus and Director U.S. Veterans Administration Undergraduate Neuroscience Program Colorado State University Barbara B Bendlin Assistant Professor Ambassador Donald and Jane K. Bandler University of Wisconsin-Madison Alzheimer’s Association Christopher Benz, MD Chicago, Illinois Buck Institute for Age Research

Steven W. Barger, Ph.D. Dr. Martin J. Berg Professor of Geriatrics, Neurobiology & Developmental Nathan S. Kline Institute Sciences University of Arkansas for Medical Sciences Oksana Berezovska Associate Professor of Neurology Warren Barker Massachusetts General Hospital Research Coordinator Mount Sinai Medical Center Ed Berger Manager Andrzej Bartke, PhD AHAF Professor Emeritus Chief, Geriatrics Research Ilya Bezprozvanny, Ph.D. Southern Illinois University Professor School of Medicine UT Southwestern Medical Center at Dallas

Nir Barzilai, MD Akhil Bhalla Professor of Medicine & Genetics Post-Doc Director, Institute for Aging Research Columbia University Albert Einstein College of Medicine Paula C. Bickford, Ph.D. James A. Haley VAMC and USF Health 4

Francis S. Collins, M.D., Ph.D. November 13, 2014 Olivier Boutaud Eileen H Bigio, M.D. Research Associate Professor Professor of Pathology Vanderbilt University Northwestern CNADC Neuropathology Core Leader Northwestern University Feinberg School of Medicine Martin Brand PhD Neuropathology Medical Director Professor The Buck Institute for Research on Aging Gal Bitan Assistant Professor Barbara Braun UCLA Executive Director Neuwirthe Foundation Karen Blank, M.D. Medical Director, Memory Disorders Center Dale E. Bredesen, M.D. Braceland Center for Mental Health and Aging Professor and Founding President, Buck Institute for Institute of Living, Hartford Hospital Age Research University of California, San Francisco Robin Blass Professor, Department of Neurology Director of National Development Case Western Reserve University Gregory J. Brewer, Ph.D. Professor, Kenneth Stark Endowed Chair in Alzheimer Marie Boltz, Ph.D., RN, GNP-BC Research Assistant Professor, NYU Southern Illinois University School of Medicine College of Nursing Departments of Neurology and Medical Microbiology, Immunology and Cell Biology Honorable Amy Bondurant Former Ambassador OECD Ab Brody, Ph.D., RN, GNP-BC Heather Born Assistant Professor, NYU Graduate student College of Nursing Baylor College of Medicine Jacob A. Brody, MD Amy R. Borenstein, Ph.D. Professor of Epidemiology Professor of Epidemiology University of Illinois at Chicago Department of Epidemiology and Biostatistics University of South Florida, Tampa, FL Holly M. Brown-Borg, Ph.D. Professor Soo Borson, M.D. University of North Dakota School of Medicine & Health Professor, Psychiatry and Behavioral Sciences Sciences (Geriatrics) University of Washington School of Medicine Guojun Bu Director, Memory Disorders and Dementia Health Professor Services Research Mayo Clinic Rochelle Buffenstein Ph.D. Sergiy Borysov Professor, Barshop Institute and Physiology Department Postdoctoral Scholar University of Texas Health Science Center at San University of South Florida, USF Health Byrd Alzheimer's Antonio Institute Louis Burgio, PhD Harold R. Johnson Professor of Social Work University of Michigan, School of Social Work 5

Francis S. Collins, M.D., Ph.D. November 13, 2014 Marianne Chanti-Ketterl, M.D., MSPH Jeffrey Burns, M.D., MS University of San Francisco Associate Professor, Neurology University of Kansas School of Medicine Neil Charness William G. Chase Professor of Psychology Mark P. Burns, Ph.D. Florida State University Assistant Professor of Neuroscience Georgetown University Ved Chauhan Head, Cellular Neurochemistry Lab Rex L. Cannon NYS Office of People with Developmental Disabilities Assistant Research Professor University of Tennessee Graduate School of Medicine Gang Chen Institute of Translational Neuroscience Anne R. Cappola, MD, ScM University of Minnesota Associate Professor of Medicine Perelman School of Medicine at the University of Yuzhi Chen Pennsylvania Principal Investigator University of Arkansas for Medical Sciences Cynthia M. Carlsson, M.D., MS Assistant Professor of Medicine, Division of Geriatrics Nancy L. Chernett, MPH, MA University of Wisconsin School of Medicine and Public Instructor Health Jefferson School of Population Health Thomas Jefferson University Christy Carter Assistant Professor Lynda Chin, MD University of Floria Anderson Cancer Center

Gemma Casadesus Jennie Chin Hansen, RN, MS, FAAN Assistant Professor Chief Executive Officer Case Western Reserve University American Geriatrics Society

Anil Cashikar Joung Il Choi Assistant Professor Assistant Professor Medical College of Georgia University of Maryland at Baltimore

Richard Cawthon Leonidas Chouliaras, M.D. Research Associate Professor Maastricht University University of Utah, Dept. of Human Genetics Erica Christen Peggy M. Cawthon Director, Core Programs Associate Scientist The Feinstein Institute for Medical Research CPMC Jin Chu Colleen Chancler, PT, MHS Post-Doctoral Fellow Site Manager of Therapy Services Temple University Good Shepherd Penn Partners at the Hospital of the University of Pennsylvania Chee Yeun Chung Senior Research Scientist Whitehead Institute 6

Francis S. Collins, M.D., Ph.D. November 13, 2014 Donald J Connor David G. Clark, M.D. Neuropsychologist Assistant Professor of Neurology Sun Health Research Institue Birmingham VA Medical Center and University of Alabama at Birmingham Patty Conrad Associate Professor Donna M. Cleary, GNP-BC Case Western Reserve University University of Arkansas for Medical Sciences Craig A. Cooney, Ph.D. ClergyAgainstAlzheimer's Investigator VAMC Little Rock Robert Cockrell, M.D. Novellus Research Mary Corcoran Ph.D. Professor, Clinical Research and Leadership Donna Cohen, Ph.D. The George Washington University Professor, Department of Aging and Mental Health Disparities Kelly Cosman Louis de la Parte Florida Mental Health Insitute Health Project Coordinator University of South Florida University of Rochester Medical Center

Greg M. Cole, Ph.D. Carl W. Cotman Associate Director Mary S. Easton Alzheimer Disease Director UCI Alzheimer’s Disease Research Center Research Center Professor of Neurology Professor, Departments of Medicine & Neurology University of California, Irvine UCLA Scott E. Counts Christopher C. Colenda, MD, MPH Assistant Professor Chancellor for Health Sciences Rush University Medical Center Robert C. Byrd Health Sciences Center West Virginia University Penny Cowan Executive Director L. Stephen Coles. M.D., Ph.D., American Chronic Pain Association Lecturer, Department of Chemistry and Biochemistry UCLA Emalee Craft Pharmacy Intern Mark R. Collins University of Arizona Glenn Foundation for Medical Research Suzanne Craft, Ph.D. Cathleen Colon-Emeric, MD, MHS Professor Duke University Medical Center University of Washington

Carol A. Colton, Ph.D. Rebecca Craik, PT, Ph.D. Professor Professor and Chair, Department of Physical Therapy Duke University Medical Center Arcadia University

Meryl Comer Paige Cramer President Graduate Student Geoffrey Beene Foundation Alzheimer's Initiative Case Western Reserve University School of Medicine

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Francis S. Collins, M.D., Ph.D. November 13, 2014 John Crary Aubrey D.N.J. de Grey, Ph.D. Assistant Professor Chief Science Officer Columbia University Medical Center SENS Foundation

Martin D. Cunningham, Ph.D. Steven T. DeKosky, MD Chairman and CSO Visiting Professor of Radiology and Psychiatry University Progression BioSciences, Inc. of Pittsburgh School of Medicine

Luciano D'Adamio, PI Jack de la Torre, M.D., Ph.D. Albert Einstein College of Medicine Senior Scientist Banner Research Institute Nabila Dahodwala, MD, MS Assistant Professor Maria De Luca Department of Neurology Assistant Professor University of Pennsylvania University of Alabama at Birmingham

John M. Daly, M.D. Kathryn Dennett Dean, School of Medicine Clinical Research Coordinator Temple University University of Utah

Robert B. Daroff, M.D. Ronald DePinho, MD Professor and Chair Emeritus of Neurology Dana Farber Cancer Institute Case Western Reerve University School of Medicine Anita L DeStefano, Ph.D. Elizabeth Dart Professor of Biostatistics Rodwell Dart Memorial Foundation Boston University School of Public Health

Ian Daugs D.P. Devanand, M.D. Research Associate Professor of Clinical Psychiatry and Neurology Banner Sun Health Research Institute College of Physicians and Surgeons, Columbia University

Mak Adam Daulatzai, M.D., Ph.D. Gilbert Di Paolo University of Melbourne, Australia Assistant Professor in Pathology and Cell Biology Columbia University Adam Davey, Ph.D. Director, Doctoral Program in Health Ecology Ramon Diaz-Arrastia, M.D., Ph.D. Temple University Professor, Department of Neurology University of Texas Southwestern Medical Center Donald A Davidoff, PhD Assistant Professor of Psychiatry - Harvard Medical Cordula Dick-Muehlke, Ph.D. School Director of Education Director, Department of Neuropsychology - McLean Institute for Memory Impairments and Neurological Hospital Disorders University of California-Irvine Kenneth L. Davis, M.D. President and CEO Brad Dickerson M.D. The Mount Sinai Medical Center Associate Professor of Neurology Harvard Medical School

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Francis S. Collins, M.D., Ph.D. November 13, 2014 Andrew Dillin, PhD Sandra B. Ellis-Grannis Salk Institute for Biological Studies Research Assistant Hilgos Foundation Kelly Dineley Associate Professor Charlotte Eliopoulos RN, MPH, PhD University of Texas Medical Branch Executive Director American Association for Long Term Care Nursing Hongxin Dong Assistant Professor E. Wesley Ely, MD, MPH Northwestern University Professor of Medicine Pulmonary and Critical Care Natacha Donoghue Assoc Director of Aging Research, VA GRECC Staff Research Associate II Vanderbilt University Medical Center UCLA Memory and Aging Research Center Corinne Engelman Rachelle S. Doody, M.D.,Ph.D. Assistant Professor Effie Marie Cain Chair in Alzheimer's Disease Research University of Wisconsin - Madison Director, Alzheimer's Disease and Memory Disorders Center Yurika Enobi Baylor College of Medicine-Department of Neurology Student San Diego State University Richard L. Doty, Ph.D. Professor and Director, Smell and Taste Center Susan Ewing University of Pennsylvania School of Medicine Senior Statistician, Department of Epidemiology and Biostatistics Giulio Draetta, MD PhD University of California at San Francisco Professor, Genomic Medicine Director, Institute for Applied Cancer Science Lisa T. Eyler, Ph.D. Member, MD Anderson - MIT - Baylor Associate Professor of Psychiatry, Neurodegeneration Consortium, University of California, San Diego The University of Texas MD Anderson Cancer Center Gregory M. Fahy Karen Duff CEO Professor Intervene Biomedical Columbia University Suzanne Faith Kevin Duff, PhD, ABPP Clinical Director Board Certified in Clinical Neuropsychology Alzheimer's Services of Cape Cod & the Islands Center for Alzheimer's Care, Imaging and Research Associate Professor, Department of Neurology Dana Falcone University of Utah Genetic Counselor University of Pennsylvania Jamie Eberling, Ph.D. Associate Director of Research Elizabeth Fauth, PhD Michael J Fox Foundation Department of Family, Consumer, and Human Development Gregory Elder Utah State University Professor Mount Sinai School of Medicine 9

Francis S. Collins, M.D., Ph.D. November 13, 2014 Leda S. Felicio M.D., Ph.D.. Medical Director, Alzheimer's Disease Cooperative Associate Clinical Professor of Medicine Study, Associate Professor, Department of University of California, San Diego Neurosciences School of Medicine Director, Exercise Stress Test Laboratory and Cardiology Patricia J Foley, MS Ed. Consult Service Coordinator VA San Diego Healthcare System Alzheimer's Day Program Herricks Community Center Isidro Ferrer Professor Brent Forester MD Institute of Neuropathology Director, Mood Disorders Division, Hospital Universitari de Bellvitge Geriatric Psychiatry Research Program Barcelona, Spain McLean Hospital Assistant Professor of Psychiatry Steve Ferris, M.D., Ph.D. Harvard Medical School Gerald and Dorothy Friedman Professor of NYU Alzheimer’s Disease Center, Director Dr. Lauren Fox of Aging & Dementia Research Center, Dept. of Staff Clinical Psychologist Psychiatry, NYU Langone Medical Center Long Beach VA Healthcare System

Els Fieremans, Ph.D. Blas Frangione, M.D., Ph.D. Assistant Professor Professor Emeritus of Pathology & Psychiatry Dept. of Radiology NYU Langone Medical Center NYU Langone Medical Center Willard M Freeman Howard Fillit, M.D. Associate Professor Executive Director Penn State College of Medicine Alzheimer's Drug Discovery Foundation Daniel Freudenberger Dr. Gina Finan Advisory Council Member Columbia University Harvard NeuroDiscovery Center

Caleb Finch, PhD Alexandra Freund University of California, Davis Program Coordinator School of Gerontology Dept of Psychiatry NYU Langone Medical Center Dr. Richard E. Fine Professor of Biochemistry Robert Friedland, M.D. Boston University School of Medicine Professor and Rudd Chair, Department of Neurology University of Louisville Richard Fisher Chief Scientific Officer Ari Gafni, Ph.D. Neurophage Pharmaceuticals Professor of Biological Chemistry Professor and Graduate Chair, Biophysics Adam S. Fleisher M.D, M.A.S. The University of Michigan Associate Director of Brain Imaging Banner Alzheimer's Institute University of California, San Diego

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Francis S. Collins, M.D., Ph.D. November 13, 2014 Veronica Galvan, Ph.D. Martha Goldstein Assistant Professor Department of Physiology and The Advancement Officer Barshop Institute for Longevity and Aging Studies Crossroads School University of Texas Health Science Center at San Antonio Cheng-Xin Gong, M.D. Head, Laboratory of Brain Metabolism Sam Gandy M.D., Ph.D. New York State Institute for Basic Research Professor of Neurology & Psychiatry Mount Sinai Paul Gottschalll Professor of Pharmacology and Toxicology Mary Ganguli MD MPH University of Arknsas for Medical Sciences Professor of Psychiatry, Neurology, and Epidemiology, University of Pittsburgh School of Medicine and Gunnar K. Gouras Graduate School of Public Health Professor of Neurology and Neuroscience Weill Cornell Medical College Guanghui Ge Research Specialist B Warren J. Goux University of Pennsylvania Associate Professor University of Texas at Dallas Carmelina Gemma Assistant Professor Neill Graff-Radford, M.D. University of South Florida Professor of Neurology Mayo College of Medicine Othman Ghribi, Ph.D. Associate Professor, Department of Pharmacology, Noreen Greatens Physiology & Therapeutics Executive Director School of Medicine and Health Sciences, University of Legacies Arts Project, Inc North Dakota Robert M Greenberg, M.D. Gary E. Gibson Co-Chair, AAGP Clinical Practice Committee Professor of Neuroscience Chief of Geriatrics and Geropsychiatry, Lutheran Weill Cornell Med Coll/Burke Med Res Inst Medical Center, Brooklyn, NY Clinical Associate Professor of Psychiatry, UMDNJ Thomas M. Gill, MD School of Medicine Yale School of Medicine Lloyd A. Greene Grover C. Gilmore Professor of Pathology and Cell Biology Dean and Professor Columbia University Case Western Reserve University Joshua Grill, Ph.D. Stephen D. Ginsberg Easton Center for Alzheimer's Disease Research Associate Professor Assistant Professor Depts. Of Psychiatry & Neuroscience & Physiology UCLA NYU Langone Medical Center Leanne Groban, M.D. Dmitry Goldgaber Wake Forest University School of Medicine Professor Stony Brook University George T. Grossberg, M.D. Samuel W. Fordyce Professor 11

Francis S. Collins, M.D., Ph.D. November 13, 2014 Director, Geriatric Psychiatry Department of Neurology & Psychiatry S. Mitchell Harman, M.D., Ph.D. Saint Louis University School of Medicine Director and President Kronos Longevity Research Institute Murray Grossman, M.D. Professor of Neurology Kathleen Hayden University of Pennsylvania School of Medicine Associate Professor Department of Psychiatry and Behavioral Sciences Andrew C. Grover Ph.D. Duke University L.J.Roberts Center of Alzheimers Research Banner Research Institute Leonard Hayflick, Ph.D. Sun City AZ Professor of Anatomy University of California, San Francisco Jaime Grutzendler Assistant Professor of Neurology Elizabeth Head Northwestern University Feinberg school of Medicine Associate Professor University of Kentucky Leonard P. Guarente, PhD Massachusetts Institute of Technology Judith L. Heidebrink, M.D. Assistant Professor of Neurolog Lisa P. Gwyther, MSW, LCSW University of Michigan Associate Professor, Department of Psychiatry Duke University Medical School Stephen Helfand, MD Brown University Karen H. Gylys, Ph.D. Associate Professor Karen Henley Mary S. Easton Center for Alzheimer's Research at UCLA Aging Research Advocate UCLA School of Nursing Westbury, NY

Lori Haase Louis B. Hersh Graduate Student George Schwert Professor and Chair SDSU/UCSD University of Kentucky

Sue Halliday Leigh Ann Hewston, PT, MEd, CEEAA Principal Asst Professor, Physical Therapy Adult Healthcare Resources, LLC Thomas Jefferson University

Barbara C. Hansen, Ph.D. James J. Hickman Professor of Internal Medicine and Pediatrics Professor University of South Florida College of Medicine University of Central Florida Hideo Hara Associate Professor Pat Hilgendorf Division of Neurology Support Group Facilitator Department of Internal Medicine MemoryCare Saga University Faculty of Medicine

Calvin Harley, Ph.D. Founder and CSO Telome Health, Inc. (THINC) 12

Francis S. Collins, M.D., Ph.D. November 13, 2014 Karen B. Hirschman, Ph.D. MSW Andrew Hwang Research Assistant Professor Research Specialist NewCourtland Center for Transitions and Health Center for Neurodegenerative Disease Research Fellow, Institute on Aging University of Pennsylvania School of Nursing Lee Hyer, Ph.D. ABPP Professor of Psychiatry and Human Behavior Nancy A. Hodgson, Ph.D., RN Mercer School of Medicine & GA Neurosurgical Institute Assistant Professor Kanae Iijima-Ando Thomas Jefferson University Assistant Professor Thomas Jefferson University Charles Hoeffer, Ph.D. Adjunct Assistant Professor Koichi Ijima Dept. of Neuroscience & Physiology Assistant Professor NYU Langone Medical Center Thomas Jefferson University

Patrick R. Hof, M.D. Donald K. Ingram Ph.D. Professor Professor, Nutritional Neuroscience and Aging Mount Sinai School of Medicine Laboratory Pennington Biomedical Research Center Donna J. Holmes, Ph.D. Director, Animal Physiology and Behavior Core Research Associate Professor LSU System Washington State University Jayme Hommer Robert C. Intrieri, Ph.D. Associate Director of Development Associate Professor Georgetown University Medical Center Western Illinois University

Robyn A. Honea David J. Irwin, M.D. Assistant Professor NRSA Postdoctoral Research Fellow University of Kansas School of Medicine University of Pennsylvania

Peter J. Hornsby Jeffree Itrich Professor Senior Communications Specialist University of Texas Health Sciences Center University of California, San Diego Alzheimer's Disease Cooperative Study Karla DeMoe Hornstein Alzheimer’s Association Awardee Walker S. Jackson Postdoctoral scholar Alma Houston Whitehead Institute Administrative Specialist Mary S. Easton Center for Alzheimer's Disease Research William Jagust UCLA Professor University of California, Berkeley Berna Huebner Director, Hilgos Foundation Hieronim Jakubowski Professor Jesse M. Hunter, Ph.D. UMDNJ-New Jersey Medical School Banner Sun Health Research Institute Dr. Kenneth A. James, MD Mayo Clinic 13

Francis S. Collins, M.D., Ph.D. November 13, 2014 Sofia Jurgensen, Msc Joanna L Jankowsky, Ph.D. Federal University of Rio de Janeiro Assistant Professor of Neuroscience Baylor College of Medicine Inga Kadish Assistant Professor Daniel Jarosz University of Alabama at Birmingham Postdoctoral Fellow Whitehead Institute for Biomedical Research Sarah H. Kagan PhD, RN Lucy Walker Honorary Term Professor of Gerontological Heinrich Jasper Nursing, School of Nursing Professor University of Pennsylvania Buck Institute for Research on Aging Arnold Kahn S. Michal Jazwinski, Ph.D. Senior Scientist Professor of Medicine California Pacific Medical Center Tulane University Director, Tulane Center for Aging Dr. Pankaj Kapahi, PhD Professor Kathryn Jedrziewski The Buck Institute for Research on Aging Deputy Director University of Pennsylvania Institute on Aging Neeraj Kapoor Postdoc Kurt Jellinger, M.D., Ph.D. Rockefeller University Professor of Neurology and Neurpathology Medical University Vienna, Vienna, Austria Jason Karlawish, MD Professor of Medicine and Medical Ethics Gregory A. Jicha University of Pennsylvania Professor of Neurology University of Kentucky Jordan F. Karp, MD Associate Professor of Psychiatry, Anesthesiology, and F. Brad Johnson, MD PhD Clinical and Translational Science Associate Professor University of Pittsburgh School of Medicine Pathology and Lab Medicine University of Pennsylvania B. S. Kasinath, M.D. Professor, Dept of Medicine Keith Johnson University of Texas Health Science Center at San Professor Antonio Radiology and Neurology Massachusetts General Hospital Loukia Katsouri Research Assistant Robert Duren Johnson, M.D. Imperial College President, Medical Doctor Pathology Consulting Services, LLC John Kauwe Assistant Professor Sterling Johnson, Ph.D. Brigham Young University Associate Professor University of Wisconsin-Madison Brian Kennedy, Ph.D. President & CEO Buck Institute for Research on Aging 14

Francis S. Collins, M.D., Ph.D. November 13, 2014 Doo Yeon Kim Frances Kennedy Asssitant Professor of Neurology Alzheimer's Caregiver Massachusetts General Hospital

Gary J. Kennedy MD Jungsu Kim Division of Geriatric Psychiatry Assistant Professor Montefiore Medical Center Washington University Albert Einstein College of Medicine Tae-Wan Kim Quinn Kennedy Associate Professor Research Associate II Columbia University Stanford University/VA Palo Alto Healthcare System Mark Kindy Kristen Kennedy Professor Post-doc Medical University of South Carolina University of Texas at Dallas Alan Kluger, MPH, Ph.D. Sunnie Kenowsky, DVM Adjunct Associate Professor Clinical Instructor Dept. of Psychiatry Dept. of Psychiatry NYU Langone Medical Center NYU Langone Medical Center Li-wen Ko, Ph.D. Cynthia Kenyon Mayo Clinic Florida American Cancer Society Research Professor University of California, San Francisco Rada Koldamova Department of Biochemistry and Biophysics Assistant Professor University of Pittsburgh Stephen B. Kern, Ph.D., OTR/L, FAOTA Associate Professor Catharine A Kopac, Ph.D., DMin, CGNP Director Entry Level Masters Program in Occupational Associate Professor Therapy The George Washington University School of Nursing Thomas Jefferson University School of Health Professions, Department of Paulette Kozlowski RN CRRN QDCS Occupational Therapy ADC & Caregiver Support Manager St. Johns County Council on Aging Inc. Diane Kerwin M.D. St. Augustine, FL Assistant Professor of Medicine Northwestern University Richard J. Kryscio Geriatrics Cognitive Neurology and Alzheimer's Disease Professor Center (CNADC) University of Kentucky

Konstantin Khrapko, Ph.D. Linda K. Kwong, Ph.D. Professor Senior Research Investigator Department of Biology Center of Neurodegenerative Disease Research Northeastern University University of Pennsylvania

Dr. Vikram Khurana Massachusetts General Hospital

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Francis S. Collins, M.D., Ph.D. November 13, 2014 Debomoy K Lahiri Professor of Neuroscience Siu Sylvia Lee, Ph.D. Department of Psychiatry Associate Professor Indiana University School of Medicine Cornell University Department of Molecular Biology and Genetics Patricia Lair Assistant to the Director Christiaan Leeuwenburgh The American University of Paris Professor University of Florida Bruce Lamb Associate Staff Scientist Iliya Lefterov The Cleveland Clinic Assistant Professor University of Pittsburgh Gary Landreth Professor of Neurosciences Malcolm A. Leissring, Ph.D. Case Western Reserve University Assistant Professor Department of Neuroscience Mayo Clinic Florida Nancy E. Lane, M.D. Dmitriev Leonid Director and Endowed Professor, Aging Center, Professor Medicine and Rheumatology Cardiology Research Center, Moscow, Russia University of California at Davis Medical Center Allan Levey, M.D., Ph.D. Dianne Langford Professor and Chair, Dept of Neurology and Director Assistant Professor Emory Alzheimer's DIsease Research Center Temple University School of Medicine Emory University

Hiuyan Lau, Ph.D. Harry LeVine, III Posdoctoral Fellow Associate Professor Dept. of Psychiatry University of Kentucky NYU Langone Medical Center Efrat Levy, Ph.D. Stephanie Lederman Associate Professor Executive Director Depts. Of Biochemistry & Molecular Pharmacology and American Federation for Aging Research(AFAR) Psychiatry NYU Langone Medical Center Gloria Lee Associate Professor Yueming Li University of Iowa Associate Professor and Lab Head Memorial Sloan-Kettering Cancer Center Edward B. Lee, M.D., Ph.D. University of Pennsylvania Daniel Lichter, PhD President, Population Association of America Virginia M.Y. Lee Cornell University Professor of Pathology and Laboratory Medicine University of Pennsylvania Liana Lisboa Fernandez, Ph.D. UFCSPA Brazil Hyoung-gon Lee Instructor Case Western Reserve University 16

Francis S. Collins, M.D., Ph.D. November 13, 2014 Gordon J. Lithgow Ph.D. Caryn MacDonald Professor Research Specialist The Buck Institute for Age Research Center for Neurodegenerative Disease Research University of Pennsylvania Nancy Emerson Lombardo, Ph.D. Boston University David Madden, PhD Assistant Professor Justin Matthew Long Touro University California Student, Medical Scientist Training Program College of Pharmacy Indiana University School of Medicine Sumihiro Maeda, Ph.D. University of California San Francisco Kimberley Larson, Executive Director Family Alliance, Inc. Ghulam M. Maharvi, Ph.D. Woodstock, Illinois Research Fellow Mayo Clinic Dawn A. Lowe Associate Professor Panchanan Maiti University of Minnesota Postdoctoral scholar UCLA Jennifer Luebke Associate Professor Susan M. Maixner, MD Boston University Assistant Professor of Psychiatry Program Director, Geriatric Psychiatry Fellowship Susan Lindquist, Ph. D. Director, Outpatient Geriatric Psychiatry Clinic Whitehead Institute for Biomedical Research University of Michigan Health System Department of Biology, MIT Howard Hughes Medical Institute Michael Malek-Ahmadi, MSPH Banner Sun Health Research Institute Irene I. Lukoff Senior Director of Development Roberto Malinow University of Pennsylvania Professor Institute on Aging and Research Partners University of California San Diego

Victoria Lunyak, PhD Ali Mansoori The Buck Institute for Research on Aging Professor of BioEngineering University of Illinois at Chicago Yuri Lyubchenko Professor Peter Marro University of Nebraska Medical Center Briteside Adult Day Center, Inc

Qiulan Ma, M.D., Ph.D Karyn Marsh, Ph.D. University of California, Los Angeles Managing Associate Director Alzheimer’s Disease Center Chera L. Maarouf NYU Langone Medical Center Research Specialist Banner Sun Health Research Institute

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Francis S. Collins, M.D., Ph.D. November 13, 2014 Gad A. Marshall, M.D. Associate Neurologist Simon Melov, Ph.D. Center for Alzheimer Research & Treatment Associate Professor & Director of Genomics Associate Medical Director of Clinical Trials The Buck Institute for Age Research Brigham and Women's Hospital Yvonne L. Michael, ScD, SM Daniel Marson, JD, Ph.D. Associate Professor, Epidemiology and Biostatistics Professor of Neurology; Director, Division of Drexel University School of Public Health Neuropsychology University of Alabama at Birmingham Laurie S. Minamide Director, Alzheimer's Disease Center Senior Research Associate Coloraod State University George M. Martin, M.D. Professor of Pathology Emeritus Jacobo Mintzer, M.D., MBA University of Washington Professor of Neurosciences & Psychiatry Medical University of South Carolina/Department of Paul Matthews, Ph.D. Neurosciences Assistant Professor Director, Division of Translational Research Dept. of Psychiatry NYU Langone Medical Center Mary Mittleman, DPH Research Professor William Maung Tay, Ph.D. Dept. of Psychiatry Mayo Clinic Jacksonville NYU Langone Medical Center

Richard Mayeux, M.D. Andrei C. Miu, Ph.D. Columbia University Associate Professor of Neuroscience and Genetics Department of Psychology, Babes-Bolyai University, Charlene McCarthy, MPH, CCRC Cluj-Napoca, Romania CSP #546 Study Coordinator Bay Pines VA Healthcare System Panaiyur Mohan, Ph.D. Bay Pines, FL Assistant Professor Dept. of Psychiatry Kathleen M. McCauley Ph.D., RN, ACNS-BC, FAAN, FAHA NYU Langone Medical Center Class of 1965 Reunion Term Professor of Cardiovascular Nursing Richard Mohs University of Pennsylvania School of Nursing Distinguished Research Fellow Eli Lilly and Co. William M. McDonald, MD JB Fuqua Chair for Late-Life Depression Juliet A. Moncaster, Ph.D. Professor of Psychiatry and Behavioral Sciences Senior Postdoctoral Associate Emory University School of Medicine Boston University School of Medicine

Wade McGregor Mervyn J. Monteiro Assistant Professor Professor Arizona State University University of Maryland, Baltimore

Laura Beth J. McIntire Karen Moran Associate Research Scientist Domestic Engineer Columbia University Moran Institute 18

Francis S. Collins, M.D., Ph.D. November 13, 2014 Michael J. Murphy. M.D., M.P.H. Paula Moreira, Ph.D. Assistant Clinical Professor Center for Neuroscience and Cell Biology Department of Psychiatry Vanderbilt University David Morgan Director, Byrd Alzheimer Institute M. Paul Murphy, M.A., Ph.D. University of South Florida Associate Professor Department of Molecular and Cellular Biochemistry Richard Morimoto, PhD University of Kentucky Department of Molecular Biosciences Center for Genetic Medicine Anne M. Murray, M.D., MSc Northwestern University Associate Professor of Medicine and Geriatrics University of Minnesota Martha Clare Morris, Sc.D. 2008-2009 Fesler Lampert Chair in Aging Studies Professor Chronic Disease Research Group Rush University Medical Center Hennepin County Medical Center

Mary F. Morrison, MD, MS, FACP Hyman B. Muss, MD Vice Chairperson for Research, Department of University of North Carolina, Psychiatry Lineberger Comprehensive Cancer Center Professor of Psychiatry, Internal Medicine and Center for Substance Abuse Research Maureen C. Nash, M.D., M.S., F.A.P.A. Temple University School of Medicine Medical Director, Tuality Center for Geriatric Psychiatry

Farzad Mortazavi, Ph.D. Mary D. Naylor Ph.D., RN Instructor Marian S. Ware Professor in Gerontology Laboratory for Cognitive Neurobiology University of Pennsylvania School of Nursing Department of Anatomy & Neurobiology Director, NewCourtland Center for Transitions and Boston University School of Medicine Health

Elliott Mufson, Ph.D. Peter T. Nelson, M.D., Ph.D. Alla and Solomon Jesmer Chair in Aging Department of Pathology, Division of Neuropathy Rush University Medical Center University of Kentucky Professor, Neurological Sciences James F. Nelson, Ph.D. Florian L. Muller, Ph.D. Professor, Department of Physiology Department of Cancer Biology, UT Health Science Center, San Antonio University of Texas MD Anderson Cancer Center Barshop Institute for Longevity and Aging Studies

Virgil Muresan Paul Newhouse, M.D. Associate Professor Jim Turner Professor of Cognitive Disorders UMDNJ - New Jersey Medical School Professor of Psychiatry, Pharmacology, and Medicine Director, Center for Cognitive Medicine, Claire Murphy, Ph.D. Department of Psychiatry Professor Vanderbilt University School of Medicine San Diego State University Louis Nguyen Graduate Student University of California, San Diego 19

Francis S. Collins, M.D., Ph.D. November 13, 2014

Michael R. Nichols Brian R. Ott, M.D. Associate Professor Professor of Neurology University of Missouri-St. Louis Alpert Medical School of Brown University

Janko Nikolich Arancio Ottavio Chairman of the Board and CEO Associate Professor American Aging Association Columbia University

Ralph Nixon, PhD, MD Jaya Padmanabhan Professor, Depts. of Psychiatry and Cell Biology, Assistant Professor Director, Silberstein Alzheimer’s Institute USF Health Byrd Alzheimer's Institute NYU Langone Medical Center Beverly Paigen, Ph.D Flavio Nobili Professor Neurologist The Jackson Laboratory, Bar Harbor, ME Dept. of Neuroscience, Ophthalmology and Genetics, University of Genoa (Italy) Howard Palmer Associate Systems Manager Catherine Nolan Washington University press officer UNESCO Michael Partain Research Specialist Martha R. Nolan Center for Neurodegenerative Research, University of Vice President, Public Policy Pennsylvania Society for Women's Health Research Sachin P. Patil Avertano Noronha, M.D. Assistant Professor Associate Professor of Neuology Widener University The University of Chicago Robia G. Pautler Chris Norris Associate Professor Associate Professor, Sanders-Brown Center on Aging Baylor College of Medicine University of Kentucky College of Medicine Arthur Peck, M.D. Michal Novak Retired Associate Clinical Professor of Psychiatry Professor Mt. Sinai School of Medicine Institute of Neuroimmunology, Slovak Academy of Sciences Kathy Peng, Ph.D. Candidate NYU Langone Medical Center S. Jay Olshansy, PhD University of Illinois at Chicago Olivia M Pereira-Smith, Ph.D. Professor Minna Oinas, M.D., Ph.D. Barshop Institute for Longevity and Aging studies Helsinki University Central Hospital Department of Cellular and Structural Biology

Bill Orr Daniel Perry Professor Founder Southern Methodist University Alliance for Aging Research 20

Francis S. Collins, M.D., Ph.D. November 13, 2014

George Perry, Ph.D. Farzaneh Pour Ansari Dean and Professor Data Manager, San Francisco Coordinating Center College of Sciences University of California at San Francisco University of Texas at San Antonio Richard Powers, M.D. Susan Peschin, MHS Professor, Department of Pathology President & CEO School of Medicine, University of Alabama at Alliance for Aging Research Birmingham

Chris Ann Phelan Domenico Pratico Company Owner Professor PHELAN Temple University

Robert J. Pignolo, M.D., Ph.D. Stanley R. Primmer Director, Ralston-Penn Clinic for Osteoporosis & Related Director Bone Disorders Supercentenarian Research Foundation Departments of Medicine & Orthopaedic Surgery University of Pennsylvania School of Medicine Dr. Daniel Promislow Ian Cali Clinical & Research Scholar, Center for FOP and University of Georgia Related Bone Disorders Jean K Quam Ph.D., L.I.C.S.W. Elizabeth Pirraglia, MA Dean and Professor, College of Education and Human Statistician, Dept. of Psychiatry Developoment NYU Langone Medical Center University of Minnesota

Genie Pritchett, MD Crystal Quinn, LMSW Geriatrician, HealthMark Research Coorindator, Dept. of Psychiatry Senior Vice President Medical Services MY Langone Medical Center Colorado Access Joseph F. Quinn, M.D. Carol L Polhamus Associate Professor, Neurology Director Oregon Health and Sciences University Natural Bridges High School Qitao Ran Tuomo Polvikoski Assistant Professor Clinical Senior Lecturer in Neuropathology University of Texas Health Science Center at San Institute for Ageing and Health, Newcastle University Antonio

Huntington Potter Margaret Rasmussen, MPH Professor Senior Research Associate, Department of Epidemiology University of South Florida and Biostatistics University of California at San Francisco William Z. Potter, M.D. Ph.D. Retired VP of Translational Neuroscience Shane L. Rea, Ph.D. Merck Research Laboratories Assistant Professor, Barshop Institute for Longevity and former Intramural Researcher within NHLI and NIMH Aging Studies University of Texas Health Science Center, San Antonio Department of Physiology 21

Francis S. Collins, M.D., Ph.D. November 13, 2014

P. Hemachandra Reddy Erik D. Roberson, M.D. Ph.D. Associate Scientist Assistant Professor of Neurology and Neurobiology Oregon National Primate Research Center University of Alabama at Birmingham

Bruce R. Reed, Ph.D John Robinson Professor, Department of Neurology University of Pennsylvania University of California, Davis Dr. Catherine M. Roe Barry Reisberg, M.D. Assistant Professor of Neurology Professor, Dept. of Psychiatry, Director of Fisher Washington University School of Medicine Alzheimer’s Disease Education and Resources Program NYU Langone Medical Center Emily Rogaslki Associate Professor ReseachersAgainstAlzheimer's Northwestern University

Margaret Rice, Ph.D. Aric Rogers, Ph. D. Professor, Depts. Of Neurosurgery & Neuroscience & Post-doctoral Fellow Physiology Buck Institute for Research on Aging NYU Langone Medical Center Dr. Alex E. Roher Kathy Richards Ph.D., RN, FAAN Neuroscientist Ralston House Term Chair in Gerontological Nursing Banner Sun Health Research Instiute University of Pennsylvania School of Nursing Jon Rose, Ph.D. Arlan Richardson, Ph.D. Psychologist Senior Research Career Scientist (STVHCS) VA Palo Alto HCS University of Texas Health Science Center at San Antonio Susanna Rosi, Ph.D Director, Barshop Institute for Longevity and Aging Assistant Professor, Brain and Spinal Injury Center Studies University of California, San Francisco

Mario C. Rico, M.D. Barry W. Rovner, MD Assistant Professor Professor, Departments of Psychiatry & Neurology Temple University School of Medicine Jefferson Hospital for Neuroscience Davis C. Ryman, M.D., Ph.D. Shari Riding Washington University School of Medicine Executive Director Oregon Alzheimer's Network Kenneth Sakauye, M.D. Professor of Psychiatry Ann Riggs, M.D. University of Tennessee Health Science Center Vice Chair of Clinical Affairs Department of Geriatrics Hiroshi Saito, Ph.D. University of Arkansas for Medical Sciences Assistant Professor, Department of Surgery University of Kentucky Brad A. Rikke, Ph.D. Alla B. Salmina Senior Research Associate Professor University of Colorado at Boulder Krasnoyarsk State Medical University Institute for Behavioral Genetics 22

Francis S. Collins, M.D., Ph.D. November 13, 2014 Stefanie Schrump Michael F. Salvatore Graduate Student Associate Professor Case Western Reserve University University of North Texas Health Science Center Eben Schwartz, Ph.D. Kumar Sambamurti Postdoctoral Fellow in Neuropsychology and Professor Neuroimaging Medical University of South Carolina Dartmouth Hitchcock Medical Center

Dr. Andrew V. Samuelson Christian Sell, Ph.D. Assistant Professor Associate Professor, Department of Pathology University of Rochester Drexel University Director, Aging Initiative Li-San Wang, Ph.D. Assistant Professor of Pathology and Laboratory Sudha Seshadri, M.D. Medicine Associate Professor of Neurology University of Pennsylvania Perelman School of Medicine Boston University School of MEdicine

David W. Sanders Norman E. Sharpless, M.D. Graduate Student Professor of Medicine and Genetics Washington University Associate Cancer Center Director for Translational Research Gene Saunders The Lineberger Comprehensive Cancer Center, 21-225 Chief Director General The University of North Carolina School of Medicine CEO/Founder Project Lifesaver International Leslie M Shaw, PhD Professor Mrissa Schafer, Ph.D. Candidate Director, Toxicology Laboratory NYU Langone Medical Center Director, Biomarker Research Laboratory Department of Pathology & Laboratory Medicine Douglas W. Scharre, M.D. Perelman School of Medicine Director, Division of Cognitive Neurology University of Pennsylvania Ohio State University Michael Shelanski, M.D., Ph.D. Helen Scharfman, Ph.D. Director, Alzheimer's Disease Research Center Professor, Depts. Of Child & Adolescent Psychiatry, Columbia University Neuroscience & Physiology NYU Langone Medical Center Jianhua Shi, M.D. New York State Institute for Basic Research Frederick A. Schmitt, Ph.D. Professor, Dept. of Neurology, Psychology Charles Shockley Sanders-Brown Center on Aging Fiscal and Business Specialist University of South Florida Nathalie Schnetz-Boutaud Research Instructor Einar M. Sigurdsson, Ph.D. Vanderbilt University Associate Professor, Depts. Of Neuroscience & Physiology & Psychiatry NYU Langone Medical Center

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Francis S. Collins, M.D., Ph.D. November 13, 2014 Megan Smithey Rebecca A. Silliman, MD, PhD Postdoctoral Fellow Professor of Medicine and Epidemiology University of Arizona Boston University Schools of Medicine and Public Health William Sonntag, Ph.D. David A. Sinclair, PhD Professor and Donald W. Reynolds Chair of Aging Harvard Medical School Research Clifford Singer, MD Oklahoma University Health Science Center Adjunct Professor, University of Maine Director, Reynolds Oklahoma Center on Aging; Chief, Division of Geriatric Mental Health and Department of Geriatric Medicine Neuropsychiatry, The Acadia Hospital and Eastern Maine Medical Center Aaron Sorensen Clinical Research Industry Specialist Neena Singh GE Healthcare Associate Professor Case Western Reserve University Diane Spencer Clinical Research Asst. Dharma Singh Khalsa, M.D. Sanders-Brown Center onAging President Alzheimer's Research and Prevention Foundation Reisa Sperling, M.D. Professor of Neurology, Harvard Medical School Nancy J. Sipes, M.D. Director, Center for Alzheimer Research and Treatment American Life Science Pharmaceuticals, Inc. Brigham and Women's Hospital and Massachusetts General Hospital Frank J .Slack Professor Richard L. Sprott, Ph.D. Yale University Former Executive Director The Ellison Medical Foundation Stanley L. Slater, MD Private Practice, Geriatric Psychiatry, Chevy Chase, MD Glenn T Stebbins Ph.D. Professor of Neurological Sciences Camy Sleeman Rush University Medical Center Marketing & Communications Specialist Dept of Psychiatry John W. Steele IV NYU Langone Medical Center Ph.D. Candidate Mount Sinai School of Medicine Gary W. Small, M.D. Parlow-Solomon Professor in Aging Paula Stern Professor of Psychiatry & Behavioral Sciences Chairwoman David Geffen School of Medicine at UCLA The Stern Group, Inc. Director, UCLA Longevity Center Robert A. Stern, Ph.D. Gail Smith Professor of Neurology, Neurosurgery, and Anatomy & Undergraduate Advisor Neurobiology University of South Florida Director of Clinical Research, BU CTE Center Director, Clinical Core, BU Alzheimer's Disease Center Ken Smith, Ph.D. Boston University School of Medicine Professor of Human Development & Family Studies University of Utah 24

Francis S. Collins, M.D., Ph.D. November 13, 2014 Katie L. Stone, Ph.D. Daniel Tardiff Senior Scientist, San Francisco Coordinating Center Postdoctoral Fellow California Pacific Medical Center-Research Institute Whitehead Institute

Joel E. Streim, MD Pierre N. Tariot, M.D. Professor of Psychiatry Memory Disorders Clinic Geriatric Psychiatry Section Banner Alzheimer’s Institute University of Pennsylvania Marc Tatar Wolfgang J. Streit Professor of Biology and Medicine Professor Brown University University of Florida Curtis Tatsuoka Randy Strong, Ph.D. Director of Biostatistics, Neurological Institute and Professor, Pharmacology and Barshop Insitute for Neurological Outcomes Center Longevity and Aging Studies Case Western Reserve University and University University of Texas Health Science Center at San Hospitals Antonio Joy L Taylor, Ph.D. Patrick M. Sullivan, PhD Stanford University Associate Professor Department Medicine, Division Geriatrics Edmond Teng Durham VA Medical Center Assistant Professor of Neurology Duke University UCLA

Sandra Swantek, M.D. Bruce Teter Associate Professor, Psychiatry and Behavioral Sciences Assistant Professor Director, Division of Geriatric Psychiatry University of California, Los Angeles Feinberg School of Medicine Northwestern University Nikolaos Tezapsidis President & CEO Robert A. Sweet, M.D. Neurotez, Inc. Professor of Psychiatry and Neurology Vice-Chair, Institutional Review Board LaDora V Thompson, Ph.D. University of Pittsburgh University of Minnesota

Junji Takeshita, M.D. Heidi A. Tissenbaum Professor and Associate Chair, Clinical Services Associate Professor Program Director, Geriatric Psychiatry University of Massachusetts Medical School Department of Psychiatry University of Hawaii Terrence Town Associate Professor Zaldy S. Tan, M.D., M.P.H. Cedars-Sinai / UCLA Assistant Professor of Medicine Harvard Medical School Kristen Triebel, Psy.D. Neuropsychologist Jun Tan University of Alabama at Birmingham Professor of Psychiatry Instructor, Dept. of Neurology University of South Florida 25

Francis S. Collins, M.D., Ph.D. November 13, 2014 Mehul A. Trivedi Derya Unutmaz, M.D. Instructor Associate Professor of Microbiology and Pathology Rush University Medical School and Medicine Director, Center for AIDS Research John Q. Trojanowski, M.D., Ph.D New York University School of Medicine William Maul Measey-Truman G. Schnabel, Jr., M.D. Professor of Geriatric Medicine and Gerontology; Brigita Urbanc Director, Institute on Aging; Director, Alzheimer's Associate Professor of Physics Disease Core Center; Drexel University University of Pennsylvania School of Medicine Director, Udall Parkinson's Research Center; USAgainstAlzheimer's Co-director, Center for Neurodegenerative Disease Research and Marian S. Ware Alzheimer Drug Discovery Saba Valadkhan Program; Professor, Department of Pathology and Assistant Professor Laboratory Medicine Case Western Reserve University

Carol M. Troy, M.D., Ph.D. Licet Valois, LMSW, MPS Associate Professor Social Worker, Dept. of Psychiatry Columbia University NYU Langone Medical Center

Karen (Karle) Truman, Ph.D. Vivianna Van Deerlin, M.D., Ph.D. President Associate Professor Dementia Caregiver Resources, Inc. University of Pennsylvania Health System Director, Molecular Pathology Lab Eugenia (Jania) Trushina, PhD Associate Professor Linda J. Van Eldik Departments of Neurology Director, Sanders-Brown Center on Aging and Pharmacology University of Kentucky Mayo Clinic Thomas Van Groen, PhD Li-Huei Tsai, PhD University of Alabama at Birmingham Professor and Director - Picower Institute for Learning and Memory Heather VanGuilder Investigator - Howard Hughes Medical Institute Postdoctoral Research Scholar Senior Associate Member, Broad Institute Penn State University Massachusetts Institute of Technology William E. Van Nostrand, PhD Debby Tsuang, M.D. Professor Professor Department of Neurosurgery University of Washington Stony Brook University

Raymond Scott Turner, MD, PhD Joycelyn Vanterpool, MD Professor of Neurology Adult and Geriatric Psychiatrist independent contractor Georgetown University Nicholas Varvel Postdoctoral Fellow Hertie Institute for Clinical Brain Research

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Francis S. Collins, M.D., Ph.D. November 13, 2014 Tracey Vause Earland, MS, OTR/L Assistant Professor, Department of Occupational Huafeng Wei, M.D., Ph.D.. Therapy, Jefferson School of Health Professions Associate Professor of Anesthesia Thomas Jefferson University University of Pennsylvania Project Director, Translational Research Activities Department of Anesthesiology and Critical Care Jefferson Center for Applied Research on Aging and Health Richard Weindruch, Ph.D. Professor, Department of Medicine Olivia J. Veatch University of Wisconsin-Madison Graduate Student Vanderbilt University Sandra Weintraub, Ph.D., ABCN/ABPP Professor of Psychiatry, Neurology and Psychology S.M. Veeranna, Ph.D. Northwestern University Assistant Professor, Dept. of Psychiatry Clinical Core Director, Northwestern Cognitive NYU Langone Medical Center Neurology And Alzheimer’s Disease Center

Irving Vega, Ph.D. Sara L. Weisenbach, Ph.D. Assistant Professor University of Michigan University of Puerto Rico Department of Biology Don Weissman, M.D. LifeScience and Healthcare, Medical Liaison Business Dr. Robert P. Vertes Development Professor Florida Atlantic University Rudi G.J. Westendorp, MD Leyden University Medical Center George Vradenburg Founder & Chairman, USAgainstAlzheimer's Terrie Fox Wetle, Ph.D. Executive Vice President, AOL/Time Warner (ret.) Dean, School of Public Health Co-convenor, Leaders Engaged in Alzheimer's Disease Professor of Health Services, Policy & Practice Brown University Meredith C. Walgren, M.D., Ph.D. Board-certified Geriatric Psychiatrist Ellen M. Wijsman, Ph.D. Marquette General Hospital System Professor , Div. of Medical Genetics and Dept. Biostatistics James Walker, PhD University of Washington, Seattle President, Association of Population Centers University of Wisconsin, Madison Thomas Wisniewski, M.D. Professor, Depts. Of Neurology, Pathology & Lary C. Walker PPsychiatry, Director of Aging and Dementia Research Professor NYU Langone Medical Center Emory University Ellen Witkowski Louise C. Walter MD Graduate student Professor Boston University University of California, San Francisco Gwendolyn T Wong Frank M. Webbe Writer and Curator Professor of Psychology Alzheimer Research Forum Florida Institute of Technology 27

Francis S. Collins, M.D., Ph.D. November 13, 2014

Elisabeth M. Wood Zaim Wadghiri Youssef, Ph.D. Genetic Counselor Assistant Professor University of Pennsylvania Depts. Of Geriatrics & Radiology NYU Langone Medical Center Andrew Wolf Research Assistant Dr. Junying Yuan Barrow Neurological Institute Harvard University

WomenAgainstAlzheimer's Michael Zagorski Professor of Chemistry Marc Wortmann Case Western Reserve University Executive Director Alzheimer's Disease International Kathleen Zahs, Ph.D. Director of Translational Research, N. Bud Grossman Dr. Selina Wray Center for Memory Research and Care Research Fellow University of Minnesota UCL Institute of Neurology Edward Zamrini, M.D. Miaozong Wu, Ph.D. Consultant and Senior Investigator Director, Translational Research Division Center for Board Certified in Geriatric Neurology Diagnostic Nanosystems Board Certified in Behavioral and Cognitive Neurology Marshall University Center for Alzheimer's Care, Imaging and Research Professor, Department of Neurology Xuemin Xu Scientist, The Brain Institute Professor University of Utah University of Tennessee Henrik Zetterberg Shi Du Yan, M.D. Head of Department Professor Institute of Neuroscience and Physiology, the Department of Pathology & Cell Biology Sahlgrenska Academy, Sweden Surgey Taub Institute for Research on Aging and Alzheimer Disease Physicians & Surgeons College of Qiang Zhang Columbia University Postdoctoral Fellow Buck institute for age research Dun-Sheng Yank, Ph.D. Assistant Professor Bin Zhang, M.D., Ph.D. Dept. of Psychiatry University of Pennsylvania NYU Langone Medical Center Bruce A. Yankner, M.D., Ph.D. Hui Zheng Harvard Medical School Professor and Director Baylor College of Medicine Xingwang Ye Postdoctoral Associate Xiongwei Zhu Northeastern University Associate Professor Case Western Reserve University Michael Yetman Research Assistant (Graduate Student) Baylor College of Medicine: Neuroscience Department 28

Francis S. Collins, M.D., Ph.D. November 13, 2014

Michael J. Zigmond Professor University of Pittsburgh

Berislav V. Zlokovic, M.D., Ph.D. Professor and Chair, Department of Physiology and Biophysics Director, Center for Neurodegeneration and Regeneration Zilkha Neurogenetic Institute Keck School of Medicine University of Southern California

Wenquan Zou Assistant Professor Case Western Reserve University

Artem Zykovich, Ph.D. Postdoctoral Fellow Buck Institute

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