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Annual technical report 2014 Department of Reproductive Health and Research including UNDP/UNFPA/UNICEF/WHO/World Bank Special Programme of Research, Development and Research Training in Human Reproduction (HRP) Department of Reproductive Health and Research, including the UNDP/UNFPA/UNICEF/WHO/World Bank Special Programme of Research, Development and Research Training in Human Reproduction (HRP) Annual Technical Report, 2014 WHO/RHR/15.10 © World Health Organization 2015 All rights reserved. Publications of the World Health Organization are available on the WHO website (www.who.int) or can be purchased from WHO Press, World Health Organization, 20 Avenue Appia, 1211 Geneva 27, Switzerland (tel.: +41 22 791 3264; fax: +41 22 791 4857; e-mail: [email protected]). Requests for permission to reproduce or translate WHO publications –whether for sale or for non-com- mercial distribution– should be addressed to WHO Press through the WHO website (www.who.int/about/ licensing/copyright_form/en/index.html). The designations employed and the presentation of the material in this publication do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted and dashed lines on maps represent approximate border lines for which there may not yet be full agreement. The mention of specific companies or of certain manufacturers’ products does not imply that they are endorsed or recommended by the World Health Organization in preference to others of a similar nature that are not mentioned. Errors and omissions excepted, the names of proprietary products are distin- guished by initial capital letters. All reasonable precautions have been taken by the World Health Organization to verify the information contained in this publication. However, the published material is being distributed without warranty of any kind, either expressed or implied. The responsibility for the interpretation and use of the material lies with the reader. In no event shall the World Health Organization be liable for damages arising from its use. Printed by the WHO Document Production Services, Geneva, Switzerland Table of contents Acronyms and abbreviations vii 1. Introduction 1 2. High-level advocacy and input to global initiatives for sexual and reproductive health 3 3. Thematic areas 11 3.1 Family planning and contraception 11 3.2 Adolescent sexual and reproductive health 29 3.3 Maternal and perinatal health 40 3.4 Preventing unsafe abortion 69 3.5 Sexually transmitted infections (STIs) and reproductive tract infections (RTIs), including multipurpose prevention technologies (MPTs) and SRH–HIV linkages 75 3.6 Cervical cancer 92 3.7 Violence against women and harmful practices, including female genital mutilation and early marriage 99 3.8 Sexual and reproductive health in humanitarian settings 110 3.9 Infertility 113 3.10 Sexual Health 123 4. Cross-cutting topics 127 4.1 Human rights and gender equality 127 4.2 Innovations 134 4.3 Biostatistics and data management 139 4.4 Advocacy and communications 142 4.5 Research project review 153 5. Research capacity strengthening, including the HRP Alliance 157 Annex A. HRP results report 2014–2015 (provisional expenditure data) 167 Annex B. Indicator report 182 Annex C. Donors 2013-2014. 202 Acronyms and abbreviations vii Acronyms and abbreviations ACS antenatal corticosteroids AHI adolescent health intervention AMR antimicrobial resistance ANC antenatal care ARV antiretroviral ASRH adolescent sexual and reproductive health ASRM American Society for Reproductive Medicine AYSRH adolescent and youth sexual and reproductive health BASTA Battling Against Syphilis – a Team Approach (listserve) BOLD Better Outcomes in Labour Difficulty (project) BV bacterial vaginosis C4-GEP Comprehensive cervical cancer control: a guide to essential practice CAF Country Accountability Framework CAPRISA Centre for AIDS Prevention and Research in Southern Africa CCM Country Coordination Mechanism CDC United States Centers for Disease Control and Prevention CEFM child, early and forced marriage CERQual Confidence in the Evidence from Reviews of Qualitative research tool CESCR Committee on Economic, Social and Cultural Rights CHAI Clinton Health Access Initiative CIRE Continuous Identification of Research Evidence CoIA Commission on Information and Accountability for Women’s and Children’s Health CONSORT Consolidated Standards of Reporting Trials CoP Communities of Practice COS controlled ovarian stimulation CRPD Committee on the Rights of Persons with Disabilities CRVS civil registration and vital statistics CSE comprehensive sexuality education DECIDE Developing and Evaluating Communication Strategies to Support Informed Decisions and Practice Based on Evidence framework DHS Demographic and Health Survey DMPA depot medroxyprogesterone acetate DP Depo-Provera DSMB Data Safety and Monitoring Board EC emergency contraception ECOWAS Economic Community of West African States ECSA-HC East, Central and Southern African Health Community viii Annual Technical Report 2014 EDC Education Development Center EMTCT elimination of mother-to-child transmission EOBC emergency obstetric care EPF European Parliamentary Forum EPMM Ending Preventable Maternal Mortality ERC see WHO-ERC ESSENCE Enhancing Support for Strengthening the Effectiveness of National Capacity Efforts EU European Union EVD Ebola virus disease FANC focused antenatal care FGM female genital mutilation FGM/C female genital mutilation/cutting FIGO International Federation of Gynecology and Obstetrics FIGO-RMC FIGO’s Reproductive Medicine Committee FP2020 Family Planning 2020 (an outcome of the 2012 London Summit on Family Planning) GAC Grants Approval Committee GAP Gender and Rights Advisory Panel GARPR Global AIDS Response Progress Reporting System GASP Gonococcal Antimicrobial Surveillance Programme GAVI GAVI Alliance GDG Guideline Development Group GEAS Global Early Adolescent Study GFF Global Financing Facility GIS geographic information systems GLOSS Global STI Surveillance System GRADE Grading Recommendations, Assessment, Development and Evaluation GREAT Guideline-driven, Research priorities, Evidence synthesis, Application of evidence, Network and Transfer of knowledge GRC Guidelines Review Committee GURM genito/urinary and reproductive medicine H4+ UNFPA, UNICEF, WHO, World Bank, UNAIDS, UN Women HCV hepatitis C virus HPV human papillomavirus HRP UNDP/UNFPA/WHO/World Bank Special Programme of Research, Development and Research Training in Human Reproduction; also: Human Reproduction Programme HSV herpes simplex virus IARC International Agency for Research on Cancer IBP Implementing Best Practices ICD International Statistical Classification of Diseases and Related Health Problems ICD-MM WHO Application of ICD-10 to deaths during pregnancy, childbirth and the puerperium (ICD-Maternal Mortality) Acronyms and abbreviations ix ICD-PM WHO Application of ICD-10 to perinatal deaths (ICD-Perinatal Mortality) ICMART International Committee Monitoring Assisted Reproductive Technologies ICPD International Conference on Population and Development ICSI intracytoplasmic sperm injection ICT information and communication technology iEtD interactive Evidence-to-Decision (tool) IFFS International Federation of Fertility Societies IMPRINT Improving the reporting of clinical trials of infertility treatments IMPT Initiative for Multipurpose Prevention Technologies IPPF International Planned Parenthood Federation IPU Inter-Parliamentary Union IRB Institutional Review Board IRP Implementation Research Platform IUD intrauterine device IUI intrauterine insemination IVB Immunization, Vaccines and Biologicals (WHO Department) IVF in vitro fertilization IWG Innovations Working Group KAP knowledge, attitudes and practices LID Long-term Institutional Development (grant) LMIC low- and middle-income countries LNG levonorgestrel LSHTM London School of Hygiene and Tropical Medicine M&E monitoring and evaluation MAPS mHealth for Assessment and Planning for Scale (tool) MCA Maternal, Newborn, Child and Adolescent Health (WHO Department) MCHIP Maternal and Child Health Integrated Program MCS Multicountry Survey MDG Millennium Development Goal MEC Medical eligibility criteria for contraceptive use MHTF Maternal Health Task Force MISP Minimum Initial Service Package MMEIG Maternal Mortality Estimation Interagency Group MMWG Maternal Morbidity Working Group MOH ministry of health MPHO medical products of human origin MPT multipurpose prevention technology MSI Marie Stopes International MSI Management Systems International MSM men who have sex with men mTERG Technical and Evidence Review Group on mHealth for RMNCH x Annual Technical Report 2014 NASG non-pneumatic anti-shock garment NCD noncommunicable disease NET-EN norethisterone enanthate NGO nongovernmental organization NIH United States National Institutes of Health NVI Noncommunicable Diseases, Disability, Violence and Injury Prevention (WHO Department) OHCHR Office of the UN High Commissioner for Human Rights OHSS ovarian hyper-stimulation syndrome OpenSRP Open Smart Register Platform PAHO Pan American Health Organization PCC Policy and Coordination Committee PCOS polycystic ovary syndrome PICO population, intervention, comparator and outcome PID pelvic inflammatory disease PMNCH Partnership for Maternal, Newborn and Child Health PMTCT prevention of mother-to-child transmission POCT point-of-care
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