Constipation • • Include: Time, Transit by Altering Stool
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Constipation It is normal to have a bowel movement (defecate) colon cancer, diabetes, stroke, hypothyroidism, anywhere from three times a day to three times or Parkinson’s disease), a week, as long as the stool (fecal matter) is soft • functional disorders, such as irritable bowel and comfortable to pass. A person experiencing syndrome, intestinal obstructions or strictures constipation has hard or lumpy stool, which is resulting from surgery, and difficult to pass. Chronic constipation affects 15- • diet and lifestyle choices, such as consuming 30% of Canadians, and is commonly found in young a diet too low in fibre and fluid, insufficient children and the elderly, occurring more frequently physical activity, and chronic use of laxatives, in females than in males. suppositories, or enemas. Transit time is the duration between when food enters the mouth and when leftover waste finally passes out as stool. A meal could take anywhere from Symptoms/Complications 12-72 hours to travel through the digestive tract. Each The increased length of time during which stool person is unique; a normal bowel movement pattern remains in the colon causes increased pressure on for one person may be very different from those of the bowels, leading to abdominal cramping and family members or friends. Some individuals have bloating. Bowel movements may occur infrequently, an irregular pattern, never knowing what to expect. resulting in hard, lumpy, dry stool, looking like Usually, before food enters the colon, most of the either many small pellets or one solid, hard, sausage- nutrients have been absorbed into the body and the shaped piece. Rectal pressure or fullness, bloating, colon’s role is to remove water. If someone has a long abdominal pain, and a sensation of incomplete transit time, meaning food passes slowly through the evacuation are common symptoms of constipation. colon, then too much water is absorbed, hardening the The slowdown in the digestive tract may also cause stool. poor appetite, back pain, and general malaise. Factors that can contribute to constipation, often Most complications result from the intense straining by altering transit time, include: needed to pass stool. These include hemorrhoids, anal • medication side-effects (e.g., some narcotics, fissures, diverticular disease, bright red streaks on antidepressants, codeine, calcium or iron the stool (rectal bleeding), and a condition in which supplements, and medications that affect the the rectal wall pushes out through the anus (rectal nervous system), prolapse). Ask for our pamphlet on Hemorrhoids, if • diseases in which there is a physiological you need more information on this topic. change to some tissue or organ of the body (e.g., radiation therapy, inflammatory bowel disease, style-photographs © Photo Bigstockphoto.com | www.badgut.org Crohn’s Disease GI Society 1 Diagnosis Food Guide, available from Health Canada, A panel of experts developed the main diagnostic and maintaining an adequate fluid intake, is the criteria for functional constipation, and update them recommended approach to prevent and manage regularly. Below are the current, Rome III, diagnostic constipation. (For more information on fibre, contact criteria*. our office.) 1. Must include two or more of the following: b. Straining during at least 25% of defecations Exercise c. Lumpy or hard stools in at least 25% of Exercise helps to move food through the colon defecations more quickly. Aerobic exercise, such as brisk d. Sensation of incomplete evacuation for at walking, accelerates your heart and breathing rates, least 25% of defecations and helps to stimulate the natural contractions of e. Sensation of anorectal obstruction/blockage intestinal muscles. for at least 25% of defecations f. Manual manoeuvres to facilitate at least 25% Physiotherapy of defecations (e.g., digital evacuation, support Pelvic dysfunction physiotherapy may include of the pelvic floor) bowel retraining, electrical stimulation, and posture g. Fewer than three defecations per week correction. 8. Loose stools are rarely present without the use of laxatives 9. Insufficient criteria for irritable bowel syndrome Medication Therapy (IBS) *Criteria fulfilled for the last 3 months with symptom If constipation does not improve with diet and onset at least 6 months prior to diagnosis lifestyle changes, then there are supplements and medications available. A physician may order a number of tests, including blood analysis, to check for abnormal levels of Bulk Forming Agents such things as thyroid hormone, electrolytes, or These are made of indigestible fibre, which glucose, and a stool sample to examine for hidden absorbs and retains fluid and helps to form a soft, (occult) blood. Other tests include a sigmoidoscopy bulky stool (e.g., Metamucil®, Prodiem®). While or colonoscopy, which are examinations with an not quick-acting, they are safe for longterm use. Add instrument that allows a physician to see the inside these to your diet gradually and increase your fluid of the rectum and colon. Colorectal screening is intake at the same time. recommended in persons older than 50 years of age. It is important to differentiate between temporary Enemas (acute) constipation and chronic constipation, as the An enema involves insertion of a liquid, usually treatments and recommendations may differ. water, into the rectum via the anus. Typically, after holding the liquid in place for a few minutes, there is an intense urgency to move the bowels. Management Always check with your healthcare provider Stool Softeners before making major changes, to be sure these These products work by holding water in the stool actions won’t interfere with other conditions you (e.g., Colace®). They are safe for long-term use and might have. for pregnant women and the elderly. Lubricants Dietary and Lifestyle Modifications Lubricant laxatives coat the colon and stool in a waterproof film, allowing it to remain soft and Diet slip easily through the intestine, usually within 6-8 Eating regular well-balanced meals and snacks hours. Don’t use these products for longer than a with high-fibre content, as outlined in Canada’s week, as some have been shown to cause vitamin 2 GI Society Crohn’s Disease www.badgut.org deficiencies and medication interactions. An Enterokinetics example of a lubricant laxative is mineral oil. Not Prucalopride succinate (Resotran®) works recommended for pregnant women or for persons by targeting the serotonin (5-HT4) receptors in who have difficulty swallowing. the digestive tract to stimulate motility (muscle movement) and has Health Canada approval for Stimulants the treatment of chronic idiopathic constipation in These laxatives increase muscle contractions to women for whom laxative treatment has failed to move food along the digestive tract more quickly provide relief. Resotran® usually produces a bowel (e.g., Ex-lax®, Dulcolax®, castor oil, senna tea, and movement within 2-3 hours and then spontaneous Senokot®). Use only for very short-term situations complete bowel movements typically begin and under the recommendation of a physician or occurring within 4-5 days of starting treatment. Side pharmacist, because repeated use could cause the effects may include nausea, diarrhea, abdominal digestive tract to become stimulant reliant. Not pain, and headache, mostly following the initial dose recommended for pregnant women. and then subsiding with ongoing treatment. Hyperosmotics Guanylate cyclase-C agonist Osmotic laxatives encourage bowel movements Linaclotide (Constella®) works by increasing by drawing water into the bowel from nearby tissue intestinal fluid secretion, which helps ease the (intestinal lumen), thereby softening stool. Some passage of stool through the digestive tract, relieving of these laxatives can cause electrolyte imbalances associated symptoms, and has Health Canada if they draw out too many nutrients and other approval for the treatment of chronic idiopathic substances with the water. They can increase thirst constipation in men and women. In clinical trials, and dehydration. There are four main types of Constella® showed a statistically significant hyperosmotics: improvement compared with placebo for complete Saline laxatives are salts dissolved in liquid; spontaneous bowel movements. The results occurred they rapidly empty all contents of the bowel, usually within the first week, often on the first day, of dosing working within 30 minutes to 3 hours. Examples and were sustained over the 12-week treatment of saline laxatives are citrate salts (e.g., Royvac®), period. Diarrhea is the most commonly noted side magnesium preparations (e.g., Phillips’® Milk of effect. Magnesia), sulfate salts, and sodium phosphate. Not intended for long-term use or for pregnant women. Lactulose laxatives are sugar-like agents that Outlook work similarly to saline laxatives but at a much Constipation can occur for many reasons, so slower rate, and are sometimes used to treat chronic treatment often requires trial and error. An individual constipation. They take 6 hours to 2 days to produce may experience a short bout of constipation and results. return to a normal routine, or it may be an ongoing Polymer laxatives consist of large molecules that health issue. With diet and lifestyle changes, and the cause the stool to hold and retain water. They are proper use of supplements and medications, most usually non-gritty, tasteless, and are well tolerated forms of constipation are manageable. If your bowel for occasional constipation. Results can