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Journal of the American Osteopathic College of Dermatology Journal of the American Osteopathic College of Dermatology Journal of the American Osteopathic College of Dermatology Journal of the American Osteopathic College of Dermatology Editors Jay S. Gottlieb, D.O., F.O.C.O.O. Stanley E. Skopit, D.O., F.A.O.C.D. Associate Editor James Q. Del Rosso, D.O., F.A.O.C.D. Editorial Review Board Earl U. Bachenberg, D.O. Richard Miller, D.O. Lloyd Cleaver, D.O. Ronald Miller, D.O. Eugene Conte, D.O. Evangelos Poulos, M.D. Monte Fox, D.O. Stephen Purcell, D.O. Sandy Goldman, D.O. Darrel Rigel, M.D. Gene Graff, D.O. Robert Schwarze, D.O. Andrew Hanly, M.D. Michael Scott, D.O. Cindy Hoffman, D.O. Eric Seiger, D..O David Horowitz, D.O. Brooks Walker, D.O Charles Hughes, D.O. Bill Way, D.O. Daniel Hurd, D.O. Schield Wikas, D.O. Mark Lebwohl, M.D. Edward Yob, D.O. Jere Mammino, D.O. 2002-2003 OFFICERS President: Robert F. Schwarze, DO President-Elect: Stanley E. Skopit, DO First Vice-President: Ronald C. Miller, DO Second Vice-President: Richard A. Miller, DO Third Vice-President: Bill V. Way, DO Secretary-Treasurer: James D. Bernard, DO Immediate Past President: Cindy F. Hoffman, DO Trustees: Daniel S. Hurd, DO Jere J. Mammino, DO Brian S. Portnoy, DO Robert J. Signore, DO Executive Director: Rebecca Mansfield, MA AOCD 1501 E Illinois Kirksville, MO 63501 800-449-2623 FAX: 660-627-2623 www.aocd.org COPYRIGHT AND PERMISSION: written permission must be obtained from the Journal of the American Osteopathic College of Der- matology for copying or reprinting text of more than half page, tables or figures. Permissions are normally granted contingent upon similar permission from the author(s), inclusion of acknowledgement of the original source, and a payment of $15 per page, table or fig- ure of reproduced material. Permission fees are waived for authors wishing to reproduce their own articles. Request for permission should be directed to JAOCD c/o AOCD PO Box 7525 Kirksville, MO 63501 Copyright 2003 by the Journal of the American Osteopathic College of Dermatology Printed by: Stoyles Graphics Services, Mason City, IA 50401 Journal of the American Osteopathic College of Dermatology 2 Journal of the American Osteopathic College of Dermatology Volume 1, Issue 1 April 2003 CONTENTS Letter From The JAOCD Editors ....................................................................................................................................................................................4 Letter from the President of the AOCD............................................................................................................................................................................5 Patient Assessment in the Treatment of Premenstrual Acne Flare with Vitamin B6 Therapy: A Two-Year Retrospective Study..................................6 Bill V. Way, D.O., Rick Lin, M.P.H.D.O., Dan J. Ladd Jr., D.O. Squamous Cell Carcinoma of the Lip ............................................................................................................................................................................10 Jay S. Gottlieb, D.O., F.O.C.O.O. Phakomatoses ................................................................................................................................................................................................................15 Kellie Mosley, D.O., Stanley E. Skopit, D.O., F.A.O.C.D. Mid-dermal Elastolysis: A Case Report and Literature Review ....................................................................................................................................18 Matthew B. Doppelt, D.O., Stanley E. Skopit, D.O., F.A.O.C.D. A Rare Case of Bleomycin Induced Flagellate Hyperpigmentation Presenting Histopathologically as an Urticarial Drug Hypersensitivity Reaction ................................................................................................................................................................23 Risa Gorin, D.O., Charles Gropper, M.D., Cindy Hoffman, D.O., Damian DiCostanzo, M.D. Cutaneous Manifistations of Sarcoidosis........................................................................................................................................................................26 Steven Israel Moreno, D.O., Stanley E. Skopit, D.O., F.A.O.C.D. Therapeutic Perspectives in Dermatology #1 ................................................................................................................................................................30 James Q. Del Rosso, D.O., F.A.O.C.D. Necrobiotic Xanthogranuloma: A Case Report and Literature Review ........................................................................................................................34 Robin I. Shecter, D.O., Brad P. Blick, D.O., M.P.H., David Tenzel, M.D., Neal Penneys, M.D., PhD., and Steven M. Abrams, M.D. Furuncular Cutaneous Myiasis ......................................................................................................................................................................................37 Jere J. Mammino, D.O. Cutaneous Anthrax and Bioterrorism ............................................................................................................................................................................41 Peter A. Vitulli, D.O., Stanley E. Skopit, D.O., F.A.O.C.D. Porokeratosis Palmaris et Plantaris Disseminata: A case report ....................................................................................................................................43 Eric Adrien Adelman, D.O. Cutaneous Manifestations of Biological Terrorism........................................................................................................................................................47 Stephen G. Mallette, D.O., David Harowitz, D.O., Mark Horowitz, D.O. First Documented Case of Fournier’s Gangrene After Dilatation and Curettage ..........................................................................................................55 Alpesh D. Desai, D.O., Tejas D. Desal, D.O., David Horowitz, D.O., Mark Horowitz, D.O. Stevens-Johnson Sydrome: Treatment with Intravenous Immunoglobulin, A Case Report and Review ......................................................................58 Charmaine Jensen, D.O., Schield Wikas, D.O., Monte Fox, D.O. Epidermotropic Metastatic Malignant Melanoma (EMMM)–a pathological variant of melanoma...............................................................................68 Julian O. Moore, D.O., Rao N. Saladi, M.D., Neal B. Shultz, M.D., Mark G. Lebwohl, M.D., Robert G. Phelps, M.D. 3 Letter From The JAOCD Editors Jay S. Gottlieb, D.O. Stanley E. Skopit, D.O. James Q. DelRosso, D.O. It is with great pride, excitement and anticipation that our dream of launching our College's first journal, the JAOCD, has come to fruition in this inaugural edition. This journal will hopefully serve several functions. The mission of the Journal of the American Osteopathic College of Dermatology serves to better the continuing education needs of the AOCD members, residents and the dermatology community at large. The JAOCD will be a vehicle for our residents throughout the country to have the opportunity for their required papers to be published during their residency program. The Journal will provide our dermatology colleagues, as well, the ability to report on interesting and rare disorders of the integumentary system. We will cover topics that will be academically challenging. We will include such areas as dermatologic therapeutic modalities, original presentation of research, brief opinions, a review of dermatology affiliated clinical studies, brief individual case reports of unusual interest, basic science as it relates to dermatology, articles emphasizing cutaneous surgery, dermatopathology, cosmetic dermatology, pharmaceutical dermatology, editorials, letters to the editors, and finally Pearls and anecdotes in dermatology. At this time we must extend our sincere appreciation to our Founding Spon- sors. These six companies, without hesitation, stepped up to the plate to back our efforts. We look forward to a long and mutually beneficial relationship with each one. Our deepest thank you goes to Allergan Skin Care, Connetics Cor- poration, Global Pathology Laboratory Services, Novartis Pharmaceuticals Corporation, Medicis-The Dermatology Company and 3M Pharmaceuticals who have made the financial commitment to see that our dream has been ful- filled. Get information about the JAOCD at www.aocd.org or e-mail us at [email protected]. Fraternally yours in Dermatology, Jay S. Gottlieb, D.O., F.O.C.O.O. (Editor) Stanley E. Skopit, D.O., F.A.O.C.D. (Editor) James Q. Del Rosso, D.O., F.A.O.C.D. (Associate Editor) 4 5 Patient Assessment in the Treatment of Premenstrual Acne Flare with Vitamin B6 Therapy: A Two-Year Retrospective Study Bill V. Way, D.O.,* Rick Lin, D.O., M.P.H.,** Dan J. Ladd Jr., D.O.*** Abstract Premenstrual acne flare (PAF) is a common condition among female acne patients. Vitamin B6 is used by some physicians to treat this condition. This study provides statistical data in support of Vitamin B6 therapy for the treatment of premenstrual acne flare. There are 67 female participants in this study. Among the 57 patients in the 100mg treatment group, 19 patients (33%) per- ceive no response while 38 patients (66%) experience positive response. Among the 21 patients in the 200mg treatment group, 5 patients (24%) did not experience any improvement of their premenstrual acne flare, while 16 patients (76%) experienced improve- ment with
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