DOCSLIB.ORG

Drosophila Information Service

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Drosophila Information Service Drosophila Information Service Number 103 December 2020 Prepared at the Department of Biology University of Oklahoma Norman, OK 73019 U.S.A. ii Dros. Inf. Serv. 103 (2020) Preface Drosophila Information Service (often called “DIS” by those in the field) was first printed in March, 1934. For those first issues, material contributed by Drosophila workers was arranged by C.B. Bridges and M. Demerec. As noted in its preface, which is reprinted in Dros. Inf. Serv. 75 (1994), Drosophila Information Service was undertaken because, “An appreciable share of credit for the fine accomplishments in Drosophila genetics is due to the broadmindedness of the original Drosophila workers who established the policy of a free exchange of material and information among all actively interested in Drosophila research. This policy has proved to be a great stimulus for the use of Drosophila material in genetic research and is directly responsible for many important contributions.” Since that first issue, DIS has continued to promote open communication. The production of this volume of DIS could not have been completed without the generous efforts of many people. Except for the special issues that contained mutant and stock information now provided in detail by FlyBase and similar material in the annual volumes, all issues are now freely-accessible from our web site: www.ou.edu/journals/dis. For early issues that only exist as aging typed or mimeographed copies, some notes and announcements have not yet been fully brought on line, but key information in those issues is available from FlyBase. We intend to fill in those gaps for historical purposes in the future. We continue to encourage all researchers to consider submitting articles that use Drosophila for teaching as well as articles that report new techniques, research results, and interesting new mutations. In the interests of honoring the long-standing philosophy of open exchange of ideas, we sometimes accept articles that have unusual or limited perspectives. We thank the many contributors from around the world who sent material for this issue, and we invite your submissions for future annual issues as well as any suggestions you have for maintaining this as a useful Drosophila research community resource. James N. Thompson, jr., Editor David Ross Boyd Professor of Biology Department of Biology University of Oklahoma, Norman Jenna J. Hellack, Associate Editor Department of Biology, Emeritus University of Central Oklahoma, Edmond Department of Biology, Adjunct Professor University of Oklahoma, Norman Contributions and Inquiries should be sent to: James N. Thompson, jr., Department of Biology, University of Oklahoma, Norman, OK 73019; Phone: (405) 325-2001, FAX (405) 325-6202, email: [email protected] Printed copies of the recent volumes can be ordered from lulu.com. Dros. Inf. Serv. 102 (2019) iii List of Contributions General Announcements Guide to Authors 74 Printed copies of Drosophila Information Service from lulu.com 104 Book Review: Held, L.I., Jr. Animal Anomalies: What Abnormal Anatomies Reveal About Normal Development. 2021. Cambridge University Press 96 Research Notes Blackmon, R.H., and G.L. Harmon. Trichostatin A enhances catalase activity in Drosophila melanogasterap56f. 24 Del Pino, F., P. Espinoza, C. Pozo, F. Gonzalez, M. Zamora, and E. Alvarez. Effect of population density on the development of Drosophila immigrans. 63 Del Pino, F., F. Claps, C. Gabilan, F. Santin, and E. Alvarez. Effect of population density on the development of Drosophila melanogaster. 64 Domit, S.G., L.M.S. Baptista, B.M. Araujo, J.P.B. Machado, and R.P. Mateus. Life history traits and esterase activity of Drosophila species of the tripunctata and guarani groups in different food resources. 47 Fonseca, B.B.E., M.C. Ferreira, L.P.B. Machado, and R.P. Mateus. Wing heritability variation in Drosophila willistoni isofemale lines from three Brazilian Atlantic Forest fragments. 35 Guruprassad, B.R. A preliminary survey of Drosophila species in the fruit market, Mysuru, Karnataka, India. 27 He, W. T. Renoni, S. Brigida, and B. Possidente. The Drosophila Antennapedia mutation is associated with sex-specific effects on circadian activity rhythms. 12 Jolfaei, C., S. Mahin, and B.E. Staveley. GFP-RNAi expression in dopaminergic neurons can reduce lifespan in Drosophila melanogaster. 68 Khadem, M. A survey of drosophilid fauna of the Guilan province in north Iran. 16 Kitagawa, H. Gene duplication of the antimicrobial peptide attacin in Japanese populations of Drosophila virilis. 53 Knox, M.T., G.L. Harmon, and R.H. Blackmon. Thermal stress induces catalase in apterous56f Drosophila melanogaster. 23 iv Dros. Inf. Serv. 103 (2020) Lammons, J.W., K.A. Faria, and J.N. Thompson, jr. Modifiers of cell death in the Drosophila wing using sequenced strains of the Drosophila melanogaster Genetic Reference panel (DGRP). 50 MacIntyre, R. Position effect variegation of the dumpy gene in Drosophila melanogaster. 31 Mahato, S.P., and K.K. Gupta. List of species of Family Drosophilidae described and recorded from North Chotanagpur Division of Jharkhand, India. 15 Mateus, R.P., E.M. Moraes, and L.P.B. Machado. Initial population size fluctuation of introduced species Zaprionus indianus in drosophilids surveys in Brazil: data from periodic collections at early invasion. 29 Paixao, J.F., and L. Madi-Ravazzi. Transferability of species-specific microsatellite primers from D. prosaltans to D. austrosaltans. 40 Santos, K.A.V., S.V. Zorzato, G.R. Salomon, L.P.B. Machado, and R.P. Mateus. Microsatellites null alleles detection in species of guarani and guaramuru groups collected in Highland Araucaria Forest of Brazil. 43 Shivanna, N., B.S. Srinath, and A.S. Tarafdar. Influence of urea on the morphology of D. melanogaster. 18 Shoben, C.R., and M.A.F. Noor. Variable fitness effects of Drosophila mutant markers across genetic backgrounds, temperatures, and containers. 9 Solodovnikov, A.A., and S.A. Lavrov. Exact breakpoints of In(1)wm4 rearrangement. 65 Spratt, S.J. A Turing machine for the Life Sciences. 57 Uysal, H., H. Celik, H. Kizilet, B. Yilmaz, M. Ozdal, and O. Gulmez. Determination of the protective effects of fungus species belonging to the genus Pleurotus against the longevity toxicity of guaiazulene in Drosophila melanogaster (Oregon R). 1 Technique Notes Cheburkanov, V., P. Alicia, A. Doan, V.V. Yakovlev, and V. Panin. Assessment of Drosophila muscle elasticity using dual Brillouin-Raman microscopy. 90 Eckert, F.B., D. de Brittos Valdati, J.M. Neto, D.C. de Toni, and C.L. de Oliveira. Lane-maze for behavioral tests in flies. 77 Graham, P.L., M.D. Fischer, and L. Pick. Efficient screening of CRISPR/Cas9 genome editing in Drosophila without a visible marker. 80 Dros. Inf. Serv. 102 (2019) v Jain, D., and S. Mohanty. Fly transcriptomics uncovers the molecular signature of cellular and tissue-specific function. 83 Massey, J.H., J. Li, and P.J. Wittkopp. A method using CO2 anesthesia to collect embryos for microinjection in Drosophila elegans. 75 Teaching Notes Borowski, N.M., M.A. Balinski, and R.C. Woodruff. Influence of stress on the somatic movement of the mariner DNA element in Drosophila simulans: II. Crowding with Drosophila melanogaster. 97 Deshpande, P., A.C. Venkatakrishnan, and A. Singh. An undergraduate cell biology laboratory exercise of Nile Red staining to mark lipid droplets in fly eye model of neurodegeneration. 99 Other Reports The North American Drosophila Board 105 vi Dros. Inf. Serv. 103 (2020) Dros. Inf. Serv. 103 (2020) 1 Research Notes Determination of the protective effects of fungus species belonging to the genus Pleurotus against the longevity toxicity of guaiazulene in Drosophila melanogaster (Oregon R). Uysal, Handan1*, Hatice Çelik1, Halit Kizilet2, Bilal Yilmaz3, Murat Özdal1, and Özlem Gülmez1. 1Department of Biology, Faculty of Science, Atatürk University, 25240, Erzurum, Turkey; 2Department of Cardiology, Erzurum Training and Research Hospital, 25100, Erzurum, Turkey; 3Department of Analytical Chemistry, Faculty of Pharmacy, Ataturk University, 25240, Erzurum, Turkey; *Corresponding author: [email protected] Abstract Lactarius indigo is an edible fungus and contains various secondary metabolites. One of these metabolites, Guaiazulene (GUA), is a kind of terpene. In this study, it was observed that Drosophila melanogaster shortened the life span of both male and female populations based on Guaiazulene's dose-time interaction (25, 50, 100, 200 ppm GUA and chronic application every three days). The average life span in the control group was 48.83 ± 1.95 days in the ♀ population and 48.30 ± 2.22 days in the ♂ population. These values in the ♀♀ were found to be 44.91 ± 1.45 to 12.11 ± 0.26 in the lowest and highest Gua application groups (25-200 ppm); in ♂♂, it decreased from 44.70 ± 1.22 to 11.44 ± 0.21 (P < 0.05). In the second part of the study, water extracts of two edible fungi, Pleurotus sajor-caju (PSCwt) and Pleurotus osteratus (POwt), were used together with GUA (200 ppm GUA+PSCwt and GUA+POwt, 1:1 v/v ratio). Both extracts showed a healing effect and increased longevity compared to 200 ppm GUA application. Namely, in GUA+PSCwt application, the longevity was extended to 21.93 ± 0.62 days for females and 19.05 ± 0.46 days for males. These values were found as 21.83 ± 0.66 and 18.75 ± 0.39 days in GUA+POwt application, respectively (P < 0.05). In this study, both fungal extracts were also analyzed by gas chromatography-mass spectrometry (GS-MS). A total of 13 and 10 components were identified in POwt and PSCwt, respectively. In addition, total phenol and flavanoid contents of two extracts were determined. Key words: Drosophila melanogaster, Lactarius indigo, Pleurotus, longevity Introduction Every living thing has a certain life span. In this process, living things are born, grow, age, and die. In accordance with the programmed genetic information, these development parameters are completed in certain processes.
Load more

Recommended publications
  • The Evolution, Diversity, and Host Associations of Rhabdoviruses Ben Longdon,1,* Gemma G
    Virus Evolution, 2015, 1(1): vev014 doi: 10.1093/ve/vev014 Research article The evolution, diversity, and host associations of rhabdoviruses Ben Longdon,1,* Gemma G. R. Murray,1 William J. Palmer,1 Jonathan P. Day,1 Darren J Parker,2,3 John J. Welch,1 Darren J. Obbard4 and Francis M. Jiggins1 1 2 Department of Genetics, University of Cambridge, Cambridge, CB2 3EH, School of Biology, University of Downloaded from St Andrews, St Andrews, KY19 9ST, UK, 3Department of Biological and Environmental Science, University of Jyva¨skyla¨, Jyva¨skyla¨, Finland and 4Institute of Evolutionary Biology, and Centre for Immunity Infection and Evolution, University of Edinburgh, Edinburgh, EH9 3JT, UK *Corresponding author: E-mail: [email protected] http://ve.oxfordjournals.org/ Abstract Metagenomic studies are leading to the discovery of a hidden diversity of RNA viruses. These new viruses are poorly characterized and new approaches are needed predict the host species these viruses pose a risk to. The rhabdoviruses are a diverse family of RNA viruses that includes important pathogens of humans, animals, and plants. We have discovered thirty-two new rhabdoviruses through a combination of our own RNA sequencing of insects and searching public sequence databases. Combining these with previously known sequences we reconstructed the phylogeny of 195 rhabdovirus by guest on December 14, 2015 sequences, and produced the most in depth analysis of the family to date. In most cases we know nothing about the biology of the viruses beyond the host they were identified from, but our dataset provides a powerful phylogenetic approach to predict which are vector-borne viruses and which are specific to vertebrates or arthropods.
    [Show full text]
  • L. Lacey Knowles
    Curriculum Vitae L. Lacey Knowles Department of Ecology and Evolutionary Biology E-mail: [email protected] Museum of Zoology, University of Michigan Orcid ID: 0000-0002-6567-4853 Ann Arbor, MI 48109-1079 POSITIONS 2015-present, Robert B. Payne Collegiate Professor, Department of Ecology and Evolutionary Biology, Curator of Insects, Museum of Zoology, University of Michigan 2012-2015, Professor, Department of Ecology and Evolutionary Biology, Curator of Insects, Museum of Zoology, University of Michigan 2008-2012, Associate Professor, Department of Ecology and Evolutionary Biology, Curator of Insects, Museum of Zoology, University of Michigan 2003-2008, Assistant Professor, Department of Ecology and Evolutionary Biology, Curator of Insects, Museum of Zoology, University of Michigan ACADEMIC APPOINTMENTS: Science Communication Fellow, Museum of Natural History, University of Michigan Member, Center for statistical Genetics, University of Michigan NIH Training Program in Genome Sciences, University of Michigan EDUCATION 2001-2002 NIH Postdoctoral Fellowship (PERT: Postdoctoral Excellence in Research and Teaching) awarded through the Center for Insect Science at the University of Arizona 1999-2001 Postdoctoral Fellowship from the National Science Foundation Research Training Group in the Analysis of Biological Diversification at the University of Arizona 1999 Ph.D., Ecology and Evolution, State University of New York at Stony Brook Dissertation title: Genealogical portraits of Pleistocene speciation and diversity patterns in montane grasshoppers 1993 M.S., Zoology, University of South Florida. Thesis title: Effects of habitat structure on community assemblages of epifaunal macroinvertebrates in seagrass systems. 1989 B.S., cum laude with honors in Marine Biology, University of North Carolina, Wilmington RESEARCH INTERESTS Speciation and processes that promote divergence Phylogenomics and statistical phylogeography Evolutionary consequences of climate change HONORS AND AWARDS *Fulbright U.S.
    [Show full text]
  • Alan Robert Templeton
    Alan Robert Templeton Charles Rebstock Professor of Biology Professor of Genetics & Biomedical Engineering Department of Biology, Campus Box 1137 Washington University St. Louis, Missouri 63130-4899, USA (phone 314-935-6868; fax 314-935-4432; e-mail [email protected]) EDUCATION A.B. (Zoology) Washington University 1969 M.A. (Statistics) University of Michigan 1972 Ph.D. (Human Genetics) University of Michigan 1972 PROFESSIONAL EXPERIENCE 1972-1974. Junior Fellow, Society of Fellows of the University of Michigan. 1974. Visiting Scholar, Department of Genetics, University of Hawaii. 1974-1977. Assistant Professor, Department of Zoology, University of Texas at Austin. 1976. Visiting Assistant Professor, Dept. de Biologia, Universidade de São Paulo, Brazil. 1977-1981. Associate Professor, Departments of Biology and Genetics, Washington University. 1981-present. Professor, Departments of Biology and Genetics, Washington University. 1983-1987. Genetics Study Section, NIH (also served as an ad hoc reviewer several times). 1984-1992: 1996-1997. Head, Evolutionary and Population Biology Program, Washington University. 1985. Visiting Professor, Department of Human Genetics, University of Michigan. 1986. Distinguished Visiting Scientist, Museum of Zoology, University of Michigan. 1986-present. Research Associate of the Missouri Botanical Garden. 1992. Elected Visiting Fellow, Merton College, University of Oxford, Oxford, United Kingdom. 2000. Visiting Professor, Technion Institute of Technology, Haifa, Israel 2001-present. Charles Rebstock Professor of Biology 2001-present. Professor of Biomedical Engineering, School of Engineering, Washington University 2002-present. Visiting Professor, Rappaport Institute, Medical School of the Technion, Israel. 2007-2010. Senior Research Associate, The Institute of Evolution, University of Haifa, Israel. 2009-present. Professor, Division of Statistical Genomics, Washington University 2010-present.
    [Show full text]
  • Another Way of Being Anisogamous in Drosophila Subgenus
    Proc. NatI. Acad. Sci. USA Vol. 91, pp. 10399-10402, October 1994 Evolution Another way of being anisogamous in Drosophila subgenus species: Giant sperm, one-to-one gamete ratio, and high zygote provisioning (evoludtion of sex/paternty asune/male-derived contrIbutIon/Drosophia liftorais/Drosopha hydei) CHRISTOPHE BRESSAC*t, ANNE FLEURYl, AND DANIEL LACHAISE* *Laboratoire Populations, Gen6tique et Evolution, Centre National de la Recherche Scientifique, F-91198 Gif-sur-Yvette Cedex, France; and *Laboratoire de Biologie Cellulaire 4, Unit6 Recherche Associ6e 1134, Universit6 Paris XI, F-91405 Orsay Cedex, France Communicated by Bruce Wallace, July 11, 1994 ABSSTRACT It is generally assume that sexes n animals within-ejaculate short sperm heteromorphism in the Dro- have arisen from a productivity versus provisioning conflict; sophila obscura species group (Sophophora subgenus) to males are those individuals producing gametes n ily giant sperm found solely within the Drosophila subgenus. small, in excess, and individually bereft of all paternity assur- The most extreme pairwise comparison of sperm length ance. A 1- to 2-cm sperm, 5-10 times as long as the male body, between these taxonomic groups represents a factor of might therefore appear an evolutionary paradox. As a matter growth of 300 (12). In all Drosophila species described so far of fact, species ofDrosophila of the Drosophila subgenus differ in this respect, sperm contain a short acrosome, a filiform from those of other subgenera by producing exclusively sperm haploid nucleus, and a flagellum composed of two inactive of that sort. We report counts of such giant costly sperm in mitochondrial derivatives (13, 14) flanking one axoneme Drosophila littondis and Drosophila hydei females, indicating along its overall length: the longer the sperm, the larger the that they are offered in exceedingly small amounts, tending to flagellum and hence the more mitochondrial material.
    [Show full text]
  • University of Mysore
    Biodata of Dr. N. B. RAMACHANDRA Ph.D, FASc PROFESSOR, AND PRINCIPAL INVESTIGATOR Chairman - Department of Studies in Genetics and Genomics Chairman- Board of Studies in Genetics and Genomics Deputy Coordinator for UGC-SAP (CAS-1), DOS in Zoology Director- University of Mysore Genome Centre (Local Secretary - 103rd Indian Science Congress 2016 Former Chairman-Board of Studies in Zoology (UG&PG) & BOS in Clinical Research & Clinical Data Management) University of Mysore, Manasagangotri, Mysuru – 570 006, INDIA [email protected] / [email protected] http://scholar.google.co.in/citations?user=CBqZv1oAAAAJ http://www.ramachandralab.com/ Phone: 0821-2419781/888 (O) ; Mobile: 09880033687 1. Date of Birth: 31.05.1958 2. Educational Qualification: 1982-88: Ph.D. in Zoology, Department of Zoology, University of Mysore, INDIA. Thesis title: "Contributions to population cytogenetics of Drosophila: Studies on interracial hybridization and B-chromosomes". 1980-82: M.Sc. in Zoology, 1st Class with 2nd Rank, University of Mysore, Mysore. 1977-80: B.Sc. (Chemistry, Botany, and Zoology), 1st class, Cauvery College, Gonicoppal, University of Mysore, INDIA. 3. Area of Specialization: 1) Drosophila Genetics and Evolution 2) Human Genetic Diseases and Genomics 4. Awards/ Recognitions: Sl.No. Year Recognition Institution “Best boy of the college” Cauvary College, Gonicoppal, Univ. 1 1980 award of Mysore. 2 1982 II Rank in M.Sc DOS in Zoology, Univ. of Mysore. Government of India Nehru Department of Biological sciences, 3 1990 Centenary British Fellowship Warwick University, Coventry, United (common wealth) Award Kingdom (not availed). 1990 - McMaster University, Department of 4. 1992 Post Doctoral Fellow Award Biochemistry, Canada University of California, Department of 1999- Senior Research Associate 5 Cell Molecular and Developmental 2000 II award Biology, Los Angeles, USA VISITING PROFESSOR- to Dept.
    [Show full text]
  • YAP1 and the Hippo Signaling Pathway Regulate Progenitor Proliferation
    YAP1 and the Hippo Signaling Pathway Regulate Progenitor Proliferation Inaugural-Dissertation to obtain the academic degree Doctor rerum naturalium (Dr. rer. nat.) submitted to the Department of Biology, Chemistry and Pharmacy, Freie Universität Berlin submitted by Dipl.-Biochem. Karin Schlegelmilch born in Berlin, Germany 2013 I conducted my doctoral studies from July 2009 until February 2013 at the Boston Children’s Hospital/ Department for Stem Cell and Regenerative Biology of Harvard University in Boston, USA under the supervision of Assistant Prof. Dr. Fernando D. Camargo. 1st Reviewer: Assistant Prof. Dr. Fernando D. Camargo, Harvard University, Boston, USA 2nd Reviewer: Prof. Dr. Petra Knaus, Freie Universität Berlin, Berlin, Germany Date of defense: Acknowledgements Most importantly, I would like to thank Assistant Professor Fernando Camargo for giving me the great opportunity to work in his laboratory, for always being there for stimulating discussions and providing guidance and support. I would also like to thank Professor Petra Knaus. Without her support and commitment, my PhD thesis abroad would not have been possible. I thank my whole family and in particular my parents, Sigrid and Walter Schlegelmilch, who have supported me in my decisions all my life. I am moreover truly grateful to my brother Ingo Schlegelmilch for all his encouragement. I am immensely grateful to Jan Riethmayer for supporting me in every possible way throughout my PhD, it means so much to me and made all the difference. I am especially thankful to have met my amiga Ingrid Carvacho during the time at Children’s Hospital. Thanks so much for always being there for me and finding the right words.
    [Show full text]
  • Analysis of Drosophila Buzzatii Transposable Elements Doctoral
    Analysis of Drosophila buzzatii transposable elements Doctoral Thesis Nuria Rius Camps Departament de Genetica` i de Microbiolog`ıa, Universitat Autonoma de Barcelona, Bellaterra (Barcelona), Spain Memoria` presentada per la Llicenciada en Biologia Nuria Rius Camps per a optar al grau de Doctora en Genetica.` Nuria Rius Camps Bellaterra, a 23 de novembre de 2015 El Doctor Alfredo Ruiz Panadero, Catedratic` del Departament de Genetica` i Microbiologia de la Fac- ultat de Biociencies` de la Universitat Autonoma` de Barcelona, CERTIFICA que Nuria Rius Camps ha dut a terme sota la seva direccio´ el treball de recerca realitzat al Departament de Genetica` i Microbiologia de la Facultat de Biociencies` de la Universitat Autonoma` de Barcelona que ha portat a l’elaboracio´ d’aquesta Tesi Doctoral titulada “Analysis of Drosophila buz- zatii transposable elements”. I perque` consti als efectes oportuns, signa el present certificat a Bellaterra, a 23 de novembre de 2015 Alfredo Ruiz Panadero I tell you all this because it’s worth recognizing that there is no such thing as an overnight success. You will do well to cultivate the resources in yourself that bring you happiness outside of success or failure. The truth is, most of us discover where we are headed when we arrive. At that time, we turn around and say, yes, this is obviously where I was going all along. It’s a good idea to try to enjoy the scenery on the detours, because you’ll probably take a few. (Bill Watterson) CONTENTS Abstract iii Resumen v 1. Introduction 1 1.1. Transposable elements .......................... 1 1.1.1.
    [Show full text]
  • 2020 Program Book
    PROGRAM BOOK Note that TAGC was cancelled and held online with a different schedule and program. This document serves as a record of the original program designed for the in-person meeting. April 22–26, 2020 Gaylord National Resort & Convention Center Metro Washington, DC TABLE OF CONTENTS About the GSA ........................................................................................................................................................ 3 Conference Organizers ...........................................................................................................................................4 General Information ...............................................................................................................................................7 Mobile App ....................................................................................................................................................7 Registration, Badges, and Pre-ordered T-shirts .............................................................................................7 Oral Presenters: Speaker Ready Room - Camellia 4.......................................................................................7 Poster Sessions and Exhibits - Prince George’s Exhibition Hall ......................................................................7 GSA Central - Booth 520 ................................................................................................................................8 Internet Access ..............................................................................................................................................8
    [Show full text]
  • During Early Embryogenesis HEIDRUN ELLINGER-ZIEGELBAUER,' ABDELMADJID K
    MOLECULAR AND CELLULAR BIOLOGY, Apr. 1994, p. 2786-2797 Vol. 14, No. 4 0270-7306/94/$04.00+0 Copyright © 1994, American Society for Microbiology FTZ-F1-Related Orphan Receptors in Xenopus laevis: Transcriptional Regulators Differentially Expressed during Early Embryogenesis HEIDRUN ELLINGER-ZIEGELBAUER,' ABDELMADJID K. HIHI,2 VINCENT LAUDET,3 HANSJORG KELLER,2 WALTER WAHLI,2 AND CHRISTINE DREYER'* Max-Planck-Institut far Entwicklungsbiologie, D-72011 Tubingen, Federal Republic of Germany'; Institut de Biologie Animale, Universite de Lausanne, CH-1015 Lausanne, Switzerland ; and Unite d'Oncologie Moleculaire, Institut Pasteur, 59019 Lille Cedex, France3 Received 27 October 1993/Returned for modification 1 December 1993/Accepted 10 January 1994 Orphan receptors of the FTZ-F1-related group of nuclear receptors (xFFlr) were identified in Xenopus laevis by isolation of cDNAs from a neurula stage library. Two cDNAs were found, which encode full-length, highly related receptor proteins, xFFlrA and B, whose closest relative known so far is the murine LRH-1 orphan receptor. xFFIrA protein expressed by a recombinant vaccinia virus system specifically binds to f1Z-F1 response elements (FRE; PyCAAGGPyCPu). In cotransfection studies, xFF1rA constitutively activates transcription, in a manner dependent on the number of FREs. The amounts of at least four mRNAs encoding full-length receptors greatly increase between gastrula and early tailbud stages and decrease at later stages. At early tailbud stages, xFTZ-F1-related antigens are found in all nuclei of the embryo. The nuclear hormone receptor superfamily includes recep- yet another class of receptors (type III). They most probably tors for steroid and thyroid hormones, vitamin D and retinoic bind as monomers to extended, unrepeated half-site motifs.
    [Show full text]
  • Diptera: Drosophilidae) in North-Eastern Argentina Revista De La Sociedad Entomológica Argentina, Vol
    Revista de la Sociedad Entomológica Argentina ISSN: 0373-5680 [email protected] Sociedad Entomológica Argentina Argentina LAVAGNINO, Nicolás J.; CARREIRA, Valeria P.; MENSCH, Julián; HASSON, Esteban; FANARA, Juan J. Geographic distribution and hosts of Zaprionus indianus (Diptera: Drosophilidae) in North-Eastern Argentina Revista de la Sociedad Entomológica Argentina, vol. 67, núm. 1-2, 2008, pp. 189-192 Sociedad Entomológica Argentina Buenos Aires, Argentina Disponible en: http://www.redalyc.org/articulo.oa?id=322028482021 Cómo citar el artículo Número completo Sistema de Información Científica Más información del artículo Red de Revistas Científicas de América Latina, el Caribe, España y Portugal Página de la revista en redalyc.org Proyecto académico sin fines de lucro, desarrollado bajo la iniciativa de acceso abierto ISSN 0373-5680 Rev. Soc. Entomol. Argent. 67 (1-2): 189-192, 2008 189 NOTA CIENTÍFICA Geographic distribution and hosts of Zaprionus indianus (Diptera: Drosophilidae) in North-Eastern Argentina LAVAGNINO, Nicolás J., Valeria P. CARREIRA, Julián MENSCH, Esteban HASSON and Juan J. FANARA Laboratorio de Evolución. Departamento de Ecología, Genética y Evolución. Facultad de Ciencias Exactas y Naturales. Universidad de Buenos Aires. Pabellón II. Ciudad Universitaria. C1428HA. Buenos Aires, Argentina; e-mail: [email protected] Distribución geográfica y hospedadores de Zaprionus indianus (Diptera: Drosophilidae) en el noreste de Argentina RESUMEN. El primer registro publicado de la especie africana Zaprionus indianus Gupta 1970 en el continente Americano se refiere a individuos observados en frutos caídos de «caqui» (Diospyros kaki Linnaei) en la ciudad de São Paulo, (Brasil) en Marzo de 1999. Desde esa fecha, esta especie ha colonizado ambientes naturales y perturbados en todo el continente.
    [Show full text]
  • Science Review of the United States Forest Service
    SCIENCE REVIEW OF THE UNITED STATES FOREST SERVICE DRAFT ENVIRONMENTAL IMPACT STATEMENT FOR NATIONAL FOREST SYSTEM LAND MANAGEMENT Summary Report 1255 23 rd Street, NW, Suite 275 Washington, DC 20037 http://www.resolv.org Tel 202-965-6381 | Fax 202-338-1264 [email protected] April 2011 SCIENCE REVIEW OF THE UNITED STATES FOREST SERVICE DRAFT ENVIRONMENTAL IMPACT STATEMENT FOR NATIONAL FOREST SYSTEM LAND MANAGEMENT Summary Report Science Reviewers*: Dr. John P. Hayes, University of Florida Dr. Alan T. Herlihy, Oregon State University Dr. Robert B. Jackson, Duke University Dr. Glenn P. Juday , University of Alaska Dr. William S. Keeton, University of Vermont Dr. Jessica E. Leahy , University of Maine Dr. Barry R. Noon, Colorado State University * Order of authors is alphabetical by last name RESOLVE Staff: Dr. Steven P. Courtney (Project Lead) Debbie Y. Lee Cover photo courtesy of Urban (http://commons.wikimedia.org/wiki/File:Muir_Wood10.JPG). is a non-partisan organization that serves as a neutral, third-party in policy decision-making. One of RESOLVE’s specialties is helping incorporate technical and scientific expertise into policy decisions. Headquartered in Washington, DC, RESOLVE works nationally and internationally on environmental, natural resource, energy, health, and land use planning issues. Visit http://www.resolv.org for more details. Contact RESOLVE at [email protected] . EXECUTIVE SUMMARY The US Forest Service asked RESOLVE to coordinate an external science review of the draft Environmental Impact Statement (DEIS) for National Forest System Land Management Planning. The basic charge of the review process was to ‘evaluate how well the proposed planning rule Draft Environmental Impact Statement (DEIS) considers the best available science.
    [Show full text]
  • Pharmacogene Regulatory Elements: from Discovery to Applications
    Smith et al. Genome Medicine 2012, 4:45 http://genomemedicine.com/content/4/5/45 REVIEW Pharmacogene regulatory elements: from discovery to applications Robin P Smith1,2†, Ernest T Lam2,3†, Svetlana Markova1, Sook Wah Yee1* and Nadav Ahituv1,2* Pharmacogenomics and gene regulatory elements: Abstract an emerging picture Regulatory elements play an important role in the Most pharmacogenomics studies to date have focused on variability of individual responses to drug treatment. coding variants of pharmacologically important proteins. This has been established through studies on three However, well-supported examples of variants in regu la- classes of elements that regulate RNA and protein tory elements of genes involved in drug response, such as abundance: promoters, enhancers and microRNAs. drug metabolizing enzymes and transporters (see review Each of these elements, and genetic variants within by Georgitsi et al. [1]), show that variants in noncoding them, are being characterized at an exponential pace regulatory sequences are also likely to be important by next-generation sequencing (NGS) technologies. In (Table 1). Th ree classes of regulatory elements have been this review, we outline examples of how each class of studied in this context: promoters, enhancers and element aff ects drug response via regulation of drug microRNAs (miRNAs). Each of these has a direct impact targets, transporters and enzymes. We also discuss on the abundance of messenger RNA (mRNA) (in the case the impact of NGS technologies such as chromatin of promoters and enhancers) and protein (in the case of immunoprecipitation sequencing (ChIP-Seq) and RNA miRNAs). Genetic variation within each of these elements sequencing (RNA-Seq), and the ramifi cations of new has been linked to human disease as well as interindividual techniques such as high-throughput chromosome diff erences in drug response.
    [Show full text]