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Prone Positioning for Open Reduction Internal Fixation of Pediatric Medial Epicondyle Fractures 34 Aristides I

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Prone Positioning for Open Reduction Internal Fixation of Pediatric Medial Epicondyle Fractures 34 Aristides I The University of Pennsylvania Orthopaedic Journal Volume 26, June 2016 Editorial Board Editors-in-Chief James M. Friedman, MD Cody D. Hillin, MD, MS Faculty Advisors Jaimo Ahn, MD, PhD Samir Mehta, MD Section Editors Joshua Rozell, MD Matthew Sloan, MD, MS Jenna Bernstein, MD Daniel Gittings, MD Zachary R. Zimmer, MD Blair Ashley, MD Daniel Lim, MD Tyler R. Morris, MD Russel N. Stitzlein, MD Nicki Zelenski, MD Jonathan Slaughter, MD VOLUME 26, JUNE 2016 iii The University of Pennsylvania Orthopaedic Journal Volume 26 June 2016 Table of Contents Letter from the Editors-in-Chief 1 Cody Hillin MD MS, James M Friedman MD Dedication: Gerald Williams MD 2 James M Friedman MD, Cody Hillin MD MS Honored & Humbled 3 Gerald R Williams MD Clinical Research Arthroplasty Techniques in Cementation for Hip Hemiarthroplasty 5 Joshua C. Rozell, MD, Neil P. Sheth, MD Novel Classification System for Bone Loss in the Setting of Revision Total Knee Arthroplasty 9 Charles L. Nelson, MD, Francis J. Aversano, BS, Nicholas Pulos, MD, Craig L. Israelite, MD, Neil P. Sheth, MD Diagnosing Infection in Patients Undergoing Conversion of Prior Internal Fixation to Total Hip Arthroplasty 13 Daniel Gittings MD, P. Maxwell Courtney MD, Blair Ashley MD, Patrick Hesketh MD, Derek Donegan MD, Neil Sheth MD Epidermal Growth Factor Receptor (EGFR) Signaling in Cartilage Prevents Osteoarthritis Progression 17 Haoruo Jia, Xiaoyuan Ma, Basak Doyran, Wei Tong, Xianrong Zhang, Motomi Enomoto-Iwamoto, Lin Han, Ling Qin Epidemiology Hot Topics in Orthopaedic Clinical Research Methodology 20 Matthew Sloan MD MS, Keith D. Baldwin MD MSPT MPH Hand Operative Technique: Use of a volar plate for restoration of volar tilt intra-operatively 14 Jenna Bernstein MD, Benjamin Gray MD Pediatrics Treatment of Hip Flexion Contracture with Psoas Lengthening Through the Middle Window of the Ilioinguinal Approach 27 Daniel Gittings MD, Jonathan Dattilo MD, Derek Donegan MD, Keith Baldwin MD Pediatric Shoulder Instability: Current Trends in Management 30 Christian A. Refakis BA, Eileen P. Storey BA, Christopher M. Brusalis BA, Theodore J. Ganley MD Prone Positioning for Open Reduction Internal Fixation of Pediatric Medial Epicondyle Fractures 34 Aristides I. Cruz Jr. MD, J. Todd R. Lawrence MD PhD, Theodore J. Ganley MD New Approach to Characterize Juvenile Osteochondritis Dissecans 37 Saba Pasha PhD, Eileen P. Storey BA, Theodore J.Ganley MD The Ponseti Method for Clubfoot Treatment in Low and Middle-Income Countries: A Systematic Review of Barriers and Solutions to Service Delivery 40 James M. Friedman MD, Rachel R. Johnson BA, Andrew M. Becker BS, David A. Spiegel MD Shoulder & Elbow Doxycycline Improves Sedentary, but not Exercised, Supraspinatus Tendon and Muscle in a Rat Model 42 Sarah I. Rooney, Daniel J. Torino, Rachel Baskin, Rameen P. Vafa, Pooja S. Khandekar, Andrew F. Kuntz, Louis J. Soslowsky Effects of Autologous Tenocyte-Seeded Nanofibrous Scaffolds in Rotator Cuff Repair are Age-Dependent 45 Huegel J, Kim DH, Cirone JM, Pardes AM, Morris TR, Nuss CA, Mauck RL, Soslowsky LJ, Kuntz AF iv UNIVERSITY OF PENNSYLVANIA ORTHOPAEDIC JOURNAL TABLE OF CONTENTS V Rat Supraspinatus Tendon Responds Acutely and Chronically to Exercise 48 Sarah I. Rooney, Daniel J. Torino, Rachel Baskin, Rameen P. Vafa, Andrew F. Kuntz, Louis J. Soslowsky Pulsed Electromagnetic Field Therapy Improves Tendon-to-Bone Healing in a Rat Rotator Cuff Repair Model 51 Jennica J Tucker, James M. Cirone, Tyler R. Morris, Courtney A. Nuss, Erik I. Waldorff, Nianli Zhang, James T. Ryaby, Louis J. Soslowsky Simvastatin Recovers Supraspinatus Tendon Mechanical and Histological Properties in a Diet-Induced Hypercholesterolemia Rat Model 54 Jennica J Tucker, Louis J. Soslowsky Spine Revisiting Anterior Stand-Alone Fixation (ASAF) Devices for the Treatment of Single Level Lumbosacral Degenerative Disease 56 Blair Ashley MD, Vincent Arlet MD Fabrication, Maturation, and Implantation of a Composite Tissue-Engineered Total Disc Replacement 58 Dong Hwa Kim, John T. Martin, Sarah E. Gullbrand, Christian G. Pfeifer, Dawn M. Elliott, Lachlan J. Smith, Harvey E. Smith, Robert L. Mauck Recapitulating the Spectrum of Intervertebral Disc Degeneration in a Large Animal Model 60 Sarah E. Gullbrand, Neil R. Malhotra, Thomas P. Schaer, Zosia Zawacki, John T. Martin, Justin Bendigo, Andrew H. Milby, George R. Dodge, Edward J. Vresilovic, Dawn M. Elliott, Robert L. Mauck, Lachlan J. Smith Sports Biomechanical Estimation of Elbow Valgus Loading in Throwing Athletes as a Means to Reduce Injury Risk 63 Ryan L. Crotin PhD CSCS, Sarah A. Zinamon BSE, John D. Kelly IV MD, Josh R. Baxter PhD Low-Fidelity Simulation: An Emerging Trend in Orthopaedic Surgical Education 65 Christopher M. Brusalis BA, Eileen P. Storey BA, Christian A. Refakis BA, Theodore J. Ganley MD Perfectionism—The Foe of Happiness 68 John D. Kelly IV MD Trauma Trauma Tips and Tricks: Measurement and Management of Compartment Syndrome 71 Tyler R. Morris, MD, Daniel P. Lim, MD, Derek J. Donegan, MD Locking Cap Designs Improve Fatigue Properties of Polyaxial Screws in Upper Extremity Applications 73 Surena Namdari MD, Samir Mehta MD, Michael Hast PhD Use of a “Kickback” Screw in Olecranon Fractures Stabilization Increases Stability 75 Samir Mehta MD, Surena Namdari MD, Michael Hast PhD Arthroscopic Lysis of Adhesions Improves Knee Range of Motion After Fixation of Intra-Articular Knee Fractures 77 Daniel Gittings MD, Patrick Hesketh BS, John Kelly IV MD, Samir Mehta MD Peroneal Nerve Palsy I: Evaluation and Diagnosis 80 Tyler R Morris MD, Keith D Baldwin MD MPH MSPT Tumor Considering Cartilage Lesions in the Evaluation of the Adult with Joint Pain 82 Russell Stitzlein MD, Kristy Weber MD Study of the Different Methods of Management of Defects After Curettage of Benign Cystic Bone Lesions 85 Ihab Badawi MD Orth, Awad Abdel Mmoniem Rafalla MD, El Sayed Abd El-halim Abdullah MD VOLUME 26, JUNE 2016 VI TABLE OF CONTENTS Basic Science Research Articles Bone Progression of Vertebral Bone Disease in Mucopolysaccharidosis VII Dogs from Birth to Skeletal Maturity 92 Sun H. Peck, Jennifer L. Kang, Joseph A. Chiaro, Neil R. Malhotra, Patricia O’Donnell, Mark E. Haskins, Margret L. Casal, Lachlan J. Smith The Critical Role of Mesenchymal Progenitors in Initiating the Secondary Ossification Center at the Epiphyseal Cartilage 94 Wei Tong , Haoruo Jia , Xiaoyuan Ma , Motomi Enomoto-Iwamoto , Ling Qin Suppression of Sclerostin Alleviates Radiation Damage to Bone by Protecting Bone forming Cells 97 Abhishek Chandra, Tiao Lin, Wei-ju Tseng, Keith Cengel, Michael A. Levine, X. Sherry Liu, Ling Qin Cartilage Temporal Dynamics of Nascent ECM Production by Chondrocytes and MSCS via Multi-Color Protein Labeling 99 Claire M. McLeod, Robert L. Mauck Matrix Degradation Enhances Cell Mobility in Dense Connective Tissues 102 Feini Qu, Miltiadis H. Zgonis, John L. Esterhai, Robert L. Mauck Platelet-Derived Growth Factor Promotes Interstitial Cell Migration in the Knee Meniscus 105 Feini Qu, Julianne L. Holloway, Michael P. Pintauro, Jason A. Burdick, Robert L. Mauck Aberrant Glycosaminoglycan Accumulation and Sulfation in Epiphyseal Cartilage in Mucopolysaccharidosis VII 108 Sun H. Peck, Jennifer L. Kang, George R. Dodge, Neil R. Malhotra, Mark E. Haskins, Lachlan J. Smith Impaired Wnt Signaling Contributes to Delayed Chondrocyte Differentiation in Mucopolysaccharidosis VII Dogs 111 Sun H. Peck, Eileen M. Shore, Neil R. Malhotra, John W. Tobias, Maurizio Pacifici, Mark E. Haskins, Lachlan J. Smith Tendon & Ligament Engineered Nanofiber Crimp Alters Scaffold Mechanics and Mesenchymal Stem Cell Mechanotransduction 114 Spencer E. Szczesny, Pang-Ching Liu, Tristan P. Driscoll , Robert L. Mauck , Pen-Hsiu G. Chao Electrospun PLGA Nanofiber Scaffolds Release Ibuprofen Faster and Degrade Slower after In Vivo Implantation 116 Corinne N Riggin, Feini Qu, Dong Hwa Kim, Julianne Huegel, David R Steinberg, Louis J Soslowsky, Robert L Mauck, Joseph Bernstein Injured Tendons Increase Lactate Synthesis and Pharmacological Inhibition of Lactate Synthesis Improves Tendon Repair 118 Motomi Enomoto-Iwamoto, Kairui Zhang, Michael W. Hast, Leslie Cantley, Masahiro Iwamoto, Louis J. Soslowsky Structure and Composition in Tendons with Altered Collagen V Expression are Location-Dependent 120 Brianne K. , Sheila M. Adams, David E. Birk , Louis J. Soslowsky Collagen V-Deficient Tendons Exhibit Altered Dynamic Mechanical Behavior at Multiple Hierarchical 124 Scales Brianne K. Connizzo, Lin Han, David E. Birk, Louis J. Soslowsky Ground Reaction Forces Are More Sensitive Gait Measures Than Temporal Parameters in Rodents Following Rotator Cuff Injury 126 Pardes AM, Freedman BR, Soslowsky LJ Immunohistochemical Analysis of Muscle Tissue Following Blunt Achilles Tendon Transection in a Rat Model 128 Tyler R Morris, Benjamin R Freedman, Pankti R Bhatt, Joshua A Gordon, Alexis A Williams, Louis J Soslowsky Sex Differences Are Present in Uninjured Achilles Tendon and Muscle 130 Pardes AM, Freedman BR, Fryhofer GW, Salka NS, Bhatt PB, Soslowsky LJ Aggressive Rehabilitation with Nonsurgical Treatment Demonstrates Improved Fatigue Mechanics and Functional Outcomes Following Achilles Tendon Rupture in an Animal Model 132 Benjamin R. Freedman , Tyler M. Morris, Courtney A. Nuss, Corinne N. Riggin, Nabeel S. Salka, Joshua A. Gordon, Aricia Shen, Daniel C. Farber,Louis J. Soslowsky UNIVERSITY OF PENNSYLVANIA ORTHOPAEDIC JOURNAL TABLE OF CONTENTS VII Other Whole-Transcriptome Profiling of Notochord-Derived Cells during Embryonic Nucleus Pulposus
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