ICO Guidelines for Glaucoma Eye Care

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ICO Guidelines for Glaucoma Eye Care

Internaꢀonal Council of Ophthalmology Guidelines for Glaucoma Eye Care

The Internaꢀonal Council of Ophthalmology (ICO) Guidelines for Glaucoma Eye Care have been developed as a supporꢀve and educaꢀonal resource for ophthalmologists and eye care providers worldwide. The goal is to improve the quality of eye care for paꢀents and to reduce the risk of vision loss from the most common forms of open and closed angle glaucoma around the world.

Core requirements for the appropriate care of open and closed angle glaucoma have been summarized, and consider low and intermediate to high resource seꢁngs.

This is the first ediꢀon of the ICO Guidelines for Glaucoma Eye Care (February 2016). They are designed to be a working document to be adapted for local use, and we hope that the Guidelines are easy to read and

translate.

2015 Task Force for Glaucoma Eye Care

Neeru Gupta, MD, PhD, MBA, Chairman Tin Aung, MBBS, PhD Nathan Congdon, MD Tanuj Dada, MD Fabian Lerner, MD Sola Olawoye, MD Serge Resnikoff, MD, PhD Ningli Wang, MD, PhD Richard Wormald, MD

Acknowledgements

We gratefully acknowledge Dr. Ivo Kocur, Medical Officer, Prevenꢀon of Blindness, World Health Organizaꢀon (WHO), Geneva, Switzerland, for his invaluable input and parꢀcipaꢀon in the discussions of the Task Force.

We sincerely thank Professor Hugh Taylor, ICO President, Melbourne, Australia, for many helpful insights during the development of these Guidelines.

  • Internaꢀonal Council of Ophthalmology | Guidelines for Glaucoma Eye Care
  • Internaꢀonal Council of Ophthalmology | Guidelines for Glaucoma Eye Care

Table of Contents

  • Introducꢀon
  • 2

  • 4
  • Iniꢀal Clinical Assessment of Glaucoma

Glaucoma Assessment and Equipment Needs Glaucoma Assessment Checklist
56
Approach to Open Angle Glaucoma Care Ongoing Open Angle Glaucoma Care Approach to Closed Angle Glaucoma Care Ongoing Care for Closed Angle Glaucoma
10 13 15 16
Indicators to Assess Glaucoma Care Programs ICO Guidelines for Glaucoma Eye Care
19 20

Internaꢀonal Council of Ophthalmology | Guidelines for Glaucoma Eye Care | Page 1

Introducꢀon

Glaucoma is the leading cause of world blindness aſter cataracts. Glaucoma refers to a group of diseases, in which opꢀc nerve damage is the common pathology that leads to vision loss. The most common types of glaucoma are open angle and closed angle forms. Worldwide, open angle and closed angle glaucoma each account for about half of all glaucoma cases. Together, they are the major cause of irreversible vision loss globally. The burden of each of these diseases varies considerably among racial and ethnic groups worldwide. For example, in western countries, vision loss from open angle glaucoma is most common, in contrast to East Asia, where vision loss from closed angle glaucoma is most common. Paꢀents with glaucoma are reported to have poorer quality of life, reduced levels of physical, emoꢀonal, and social well-being, and uꢀlize more health care resources.

High intraocular pressure (IOP) is a major risk factor for loss of sight from both open and closed angle glaucoma, and the only one that is modifiable. The risk of blindness depends on the height of the intraocular pressure, severity of disease, age of onset, and other determinants of suscepꢀbility, such as family history of glaucoma. Epidemiological studies and clinical trials have shown that opꢀmal control of IOP reduces the risk of opꢀc nerve damage and slows disease progression. Lowering IOP is the only intervenꢀon proven to prevent the loss of sight from glaucoma.

Glaucoma should be ruled out as part of every regular eye examinaꢀon, since complaints of vision loss may not be present. Differenꢀaꢀng open from closed angle glaucoma is essenꢀal from a therapeuꢀc standpoint, because each form of the disease has unique management consideraꢀons and intervenꢀons. Once the correct diagnosis of open or closed angle glaucoma has been made, appropriate steps can be taken through medicaꢀons, laser, and microsurgery. This approach can prevent severe vision loss and disability from sight threatening glaucoma.

In low resource seꢁngs, managing paꢀents with glaucoma has unique challenges. Inability to pay, treatment rejecꢀon, poor compliance, and lack of educaꢀon and awareness, are all barriers to good glaucoma care. Most paꢀents are unaware of glaucoma disease, and by the ꢀme they present, many have lost significant vision. Long distances from healthcare faciliꢀes, and insufficient medical professionals and equipment, add to the difficulty in treaꢀng glaucoma. A diagnosis of open or closed angle glaucoma requires medical and surgical intervenꢀons to prevent vision loss and to preserve quality of life. Prevenꢀng glaucoma blindness in underserved regions requires heightened aꢂenꢀon to local educaꢀonal needs, availability of experꢀse, and basic infrastructure requirements.

There is strong support to integrate glaucoma care within comprehensive eye care programs and to consider rehabilitaꢀon aspects of care. Persistent efforts to support effecꢀve and accessible care for glaucoma are needed.1

1. Universal Eye Health: A Global Acꢀon Plan 2014-2019, WHO, 2013 www.who.int/blindness/

acꢀonplan/en/.

Internaꢀonal Council of Ophthalmology | Guidelines for Glaucoma Eye Care | Page 2

Open Angle Glaucoma
Closed Angle Glaucoma

In open angle glaucoma, there is characterisꢀc opꢀc nerve damage and loss of visual funcꢀon in the presence of an open angle with no idenꢀfying pathology. The disease is chronic and progressive. Although elevated IOP is oſten associated with the disease, elevated IOP is not necessary to make the diagnosis. Risk factors for the disease include elevated intraocular pressure, increasing age, posiꢀve family history, racial background, myopia, thin corneas, hypertension, and diabetes. Paꢀents with elevated IOP or other risk factors should be followed regularly for the development of glaucoma.
In closed angle glaucoma, opꢀc nerve damage and vision loss may occur in the presence of an anatomical block of the anterior chamber angle by the iris. This may lead to elevated intraocular pressure and opꢀc nerve damage. In acute angle closure glaucoma, the disease may be painful, needing emergency care. More oſten the disease is chronic, progressive, and without symptoms. Risk factors for the disease include racial background, increasing age, female gender, posiꢀve family history, and hyperopia. Paꢀents with these risk factors should be followed regularly for the development of closed angle glaucoma.

 Open Angle
 Closed Angle
 Glaucomatous Opꢀc Nerve Damage
±±±
Elevated IOP
±±
Elevated IOP
Glaucomatous Opꢀc Nerve Damage Visual Field Damage
Visual Field Damage
Most paꢀents with open and closed angle forms of glaucoma are unaware they have sightthreatening disease. Mass populaꢀon screening is not currently recommended. However, all paꢀents presenꢀng for eye care should be reviewed for glaucoma risk factors and undergo clinical examinaꢀon to rule out glaucoma. Paꢀents with glaucoma should be told to alert brothers, sisters, parents, sons, and daughters that they have a higher risk of developing disease, and that they also need to be checked regularly for glaucoma. The ability to make an accurate diagnosis of glaucoma, to determine whether it is an open or closed form, and to assess disease severity and stability, are essenꢀal to glaucoma care strategies and blindness prevenꢀon.

Internaꢀonal Council of Ophthalmology | Guidelines for Glaucoma Eye Care | Page 3

Iniꢀal Clinical Assessment of Glaucoma

History

Assessment for glaucoma includes asking about complaints that may relate to glaucoma such as vision loss, pain, redness, and halos around lights. The onset, duraꢀon, locaꢀon, and severity of symptoms should be noted. All paꢀents should be asked about family members with glaucoma, and a detailed history should also be taken.

Table 1 - History Checklist

 Chief Complaint  Age, Race, Occupaꢀon  Social History  Possibility of Pregnancy  Family History of Glaucoma  Past Eye Disease, Surgery, or Trauma  Corꢀcosteroid Use  Eye Medicaꢀons  Systemic Medicaꢀons  Drug Allergies  Tobacco, Alcohol, Drug Use  Diabetes  Lung Disease  Heart Disease  Cerebrovascular Disease  Hypertension/Hypotension  Renal Stones  Migraine  Raynaud's Disease  Review of Systems

Iniꢀal Glaucoma Assessment

Evaluaꢀon for glaucoma is recommended as part of a comprehensive eye exam. The ability to diagnose glaucoma in its open or closed angle forms, and to evaluate its severity, are criꢀcal to glaucoma care approaches and the prevenꢀon of blindness. Core examinaꢀon and equipment needs to diagnose and monitor glaucoma paꢀents are listed in Table 2.

Internaꢀonal Council of Ophthalmology | Guidelines for Glaucoma Eye Care | Page 4

Table 2 - Glaucoma Assessment and Equipment Needs - Internaꢀonal Recommendaꢀons

Opꢀonal Equipment

(Intermediate /
High Resource Seꢁngs)

Minimal Equipment

(Low Resource Seꢁngs)

Clinical Assessment

Visual Acuity

Near reading card or distance chart with 5 standard leꢂers or symbols
3- or 4-meter visual acuity lane with high contrast visual acuity chart
Pinhole

Trial frame and lenses

Phoropter

Refracꢀon

  • Reꢀnoscope, Jackson cross-cylinder
  • Autorefractor

Pupils

Pen light or torch Slit lamp biomicroscope Keratometer

Anterior Segment

Corneal pachymeter
Goldmann applanaꢀon tonometer
Tonopen
Portable handheld applanaꢀon

tonometer

Intraocular Pressure

Pneumotonometer
Schiotz tonometer

Anterior segment opꢀcal coherence tomography
Slit lamp gonioscopy

Angle Structures

Goldmann, Zeiss/Posner goniolenses
Ultrasound biomicroscopy

Fundus photography

  • Direct ophthalmoscope
  • Opꢀc nerve image analyzers

Confocal scanning laser ophthalmoscopy

Opꢀc Nerve

(dilated if angle open)
Slit lamp biomicroscopy with hand held 78 or 90 diopter lens

Opꢀcal coherence tomography Scanning laser polarimetry

Direct ophthalmoscope Head mounted indirect ophthalmoscope with 20 or 25 diopter lens

Fundus

12 and 30 diopter lenses 60 and 90 diopter lenses
Slit lamp biomicroscopy with 78 diopter lens

Frequency doubling technology Short wave automated perimetry
Manual perimetry or automated white on white perimetry

Visual Field

Internaꢀonal Council of Ophthalmology | Guidelines for Glaucoma Eye Care | Page 5

Glaucoma Assessment Checklist



Corneal Thickness

Visual Acuity

The thickness of the cornea is measured to help interpret IOP readings. Thick corneas tend to overesꢀmate the IOP reading, and thin corneas tend to underesꢀmate the reading.
Vision should be tested (undilated), unaided, and with best correcꢀon at distance and near. Central vision may be affected in advanced glaucoma.

Refracꢀve Error
Intraocular Pressure

The refracꢀve error will help to understand the risk of open angle glaucoma (myopia) or closed angle glaucoma (hyperopia). Neutralizing the error is important to assessing visual acuity and visual fields.
IOP should be measured in each eye before gonioscopy and before dilaꢀon. Recording the ꢀme of IOP measurement

is recommended to account for diurnal

variaꢀon.



Pupils
Anterior Segment

Pupils should be tested for reacꢀvity and afferent pupillary defect. An afferent defect may signal asymmetric moderate to advanced glaucoma.
The anterior segment should be examined in the undilated state and aſter dilaꢀon (if the angle is open). Look for anterior chamber shallowing and peripheral depth, pseudoexfoliaꢀon, pigment dispersion, inflammaꢀon and neovascularizaꢀon, or other causes of glaucoma.

Lids/Sclera/ Conjuncꢀva

Evidence of inflammaꢀon, redness, ocular surface disease, or local pathology may point to uncontrolled IOP due to acute or chronic angle closure, or possible glaucoma drug allergy, or other disease.

Cornea

The cornea should be examined for edema, which may be seen in acute or chronic high IOP. Note that IOP readings are underesꢀmated in the presence of corneal edema. Corneal precipitates may indicate inflammaꢀon.

Internaꢀonal Council of Ophthalmology | Guidelines for Glaucoma Eye Care | Page 6

Glaucoma Assessment Checklist (cont’d)

Angle Structures

The angle should be examined for the presence of iris contact with the trabecular meshwork in a dark room seꢁng. The locaꢀon and extent, and whether it is due to apposiꢀonal or synechial closure, should be determined by indentaꢀon gonioscopy. The presence of inflammaꢀon, pseudoexfoliaꢀon, neovascularizaꢀon, and other pathology should be noted.

Open angle on gonioscopy

Iris

The iris should be examined for mobility and irregularity, the presence of anterior and posterior synechiae, and pseudoexfoliaꢀon at the pupil margin. Forward bowing, peripheral angle crowding, and iris inserꢀon should be noted in addiꢀon to the presence of inflammaꢀon, neovascularizaꢀon, and other pathology.

Lens

The lens should be examined for cataract, size, posiꢀon, posterior synechiae, pseudoexfoliaꢀon material, and evidence of inflammaꢀon.

Closed angle on gonioscopy with no structures visible Plateau iris with peripheral iris roll
Pseudoexfoliaꢀon deposits at the pupil margin

Internaꢀonal Council of Ophthalmology | Guidelines for Glaucoma Eye Care | Page 7

Glaucoma Assessment Checklist (cont’d)

Opꢀc Nerve

The opꢀc nerve should be evaluated for characterisꢀc signs of glaucoma. The degree of opꢀc nerve damage helps to guide iniꢀal treatment goals.

• Early opꢀc nerve damage may include a cup ≥0.5, focal reꢀnal nerve fiber layer defects, focal rim thinning, verꢀcal cupping, cup/disc asymmetry, focal excavaꢀon, disc hemorrhage, and departure from the ISNT rule (rim thickest inferiorly, then superiorly, nasally and temporally).

• Moderate to advanced opꢀc nerve damage may include a large cup ≥ 0.7, diffuse reꢀnal nerve fiber defects, diffuse rim thinning, opꢀc nerve excavaꢀon, acquired pit of the opꢀc nerve, and disc hemorrhage.

Reꢀnal nerve fiber layer defect
Thinning of the inferior rim

Advanced glaucoma with 0.9 verꢀcal cup
Disc hemorrhage at 5 o’clock

Internaꢀonal Council of Ophthalmology | Guidelines for Glaucoma Eye Care | Page 8

Glaucoma Assessment Checklist (cont’d)

Fundus

The posterior pole should be evaluated for the presence of diabeꢀc reꢀnopathy, macular degeneraꢀon, and other reꢀnal disorders. See the ICO Guidelines for Diabeꢀc Eye Care at:

www.icoph.org/downloads/ICOGuidelinesforDiabeꢀcEyeCare.pdf.

The Visual Field

Preserving visual funcꢀon is the goal of all glaucoma management. The visual field is a measure of visual funcꢀon that is not captured by the visual acuity test. Visual field tesꢀng idenꢀfies, locates, and quanꢀfies the extent of field loss. The presence of visual field damage may indicate moderate to advanced disease. Monitoring the visual field is important to determine disease instability as seen below.

Progressive vision loss over ꢀme

Internaꢀonal Council of Ophthalmology | Guidelines for Glaucoma Eye Care | Page 9

Approach to Open Angle Glaucoma Care

A diagnosis of open angle glaucoma requires medical and possible surgical intervenꢀon to prevent vision loss and to preserve quality of life. Once a diagnosis of open angle glaucoma is made, paꢀent educaꢀon should begin regarding the nature of the disease, the need to lower IOP, along with discussions of treatment opꢀons. Paꢀents should be informed of the need to alert first degree relaꢀves for the need of a glaucoma examinaꢀon.

The financial, physical, social, emoꢀonal, and occupaꢀonal burdens of glaucoma treatment opꢀons should be carefully considered for each paꢀent. Recommendaꢀons, risks, opꢀons, and consequences of no treatment, should be discussed with all paꢀents in language that is understandable to the paꢀent or caregiver. Classifying glaucoma disease as early, or moderate to advanced, can help to guide IOP treatment goals and approaches. A simplified approach to iniꢀaꢀng care in glaucoma paꢀents is summarized below in Table 3.

Table 3 - Iniꢀaꢀng Open Angle Glaucoma Care - Internaꢀonal Recommendaꢀons

Glaucoma Severity
Suggested IOP
Reducꢀon

  • Findings
  • Treatment Consideraꢀons

Medicaꢀon or

Opꢀc Nerve Damage
Lower IOP

≥25%

Early

±

Laser trabeculoplasty
Visual Field Loss

Medicaꢀon or

Laser trabeculoplasty or
Opꢀc Nerve Damage
Trabeculectomy ± Mitomycin C

or Tube (± cataract removal and intraocular lens [IOL]) and/or
Lower IOP ≥25 – 50%

Moderate/ Advanced

+

Visual Field Loss
Cyclophotocoagulaꢀon (or cryotherapy)

Medicaꢀon and/or

  • Blind Eye
  • Lower IOP

≥25 – 50% (If painful)

End-stage

(Refractory glaucoma)
Cyclophotocoagulaꢀon

(or cryotherapy) and

±

Pain
Rehabilitaꢀon Services

Low resource seꢁngs pose unique challenges depending on the region. Parꢀcular aꢂenꢀon should be given to compliance with treatments and the capacity of the paꢀent to obtain and use medicaꢀon. If a paꢀent cannot afford the cost of drugs, iniꢀal laser trabeculoplasty would be favored wherever equipment and experꢀse are available. If resources to manage glaucoma are insufficient, referral

is indicated.

Internaꢀonal Council of Ophthalmology | Guidelines for Glaucoma Eye Care | Page 10

Table 4 - Medicines for Glaucoma Care: Internaꢀonal Recommendaꢀons

Essenꢀal Medicines
Opꢀonal Medicines

(Intermediate /
High Resource Seꢁngs)

Eye Drops

(Low Resource Seꢁngs)

Anestheꢀc Diagnosꢀc

Tetracaine 0.5% Fluorescein 1% Tropicamide 0.5%

Pupil Constricꢀng Pupil Dilaꢀng

Pilocarpine 2% or 4% Atropine 0.1, 0.5, or 1% Homatropine or cyclopentolate

Anꢀ-Inflammatory Anꢀ-Infecꢀves

Prednisolone 0.5% or 1% Ofloxacin 0.3%, gentamycin 0.3% or azithromycin 1.5%

Prostaglandin analogs Other beta blockers

Intraocular Pressure Lowering
(Topical)

Latanoprost 50µg/mL Timolol 0.25% or 0.5%
Carbonic anhydrase inhibitors Alpha agonists Fixed combinaꢀon drops

Intraocular Pressure Lowering
(Systemic)

  • Oral and IV acetazolamide
  • Methazolamide

  • IV mannitol 10% or 20%
  • Glycerol

See the 19th WHO Model List of Essenꢀal Medicines (April 2015), by going to:

www.who.int/medicines/publicaꢀons/essenꢀalmedicines/en/.

An ethical approach is indispensable to quality clinical care. Download the ICO Code of Ethics at:

www.icoph.org/downloads/icoethicalcode.pdf.

Internaꢀonal Council of Ophthalmology | Guidelines for Glaucoma Eye Care | Page 11

Table 5 - Laser Trabeculoplasty for Glaucoma: Internaꢀonal Recommendaꢀons

Treatment Parameters
Argon Laser Trabeculoplasty
(ALT)
Selecꢀve Laser Trabeculoplasty
(SLT)

Frequency doubled Q-Switched Nd: Yag Laser (532 nm)

Laser Type

Argon green or blue-green / Diode Laser

Spot Size

50 microns (Argon) or 75 microns (diode) 400 microns

Power

  • 300 to 1000 mW
  • 0.5 to 2 mJ

Applicaꢀon Site

  • TM juncꢀon non-pigmented/pigmented
  • Trabecular meshwork (TM)

Goldmann gonioscopy lens or Ritch lens

Handheld Lens

Goldmann or SLT lens 180 – 360 degrees

Treated Circumference

180 – 360 degrees

Number of Burns Number of Siꢁngs

~ 50 spots per 180 degrees 1 or 2
~ 50 spots per 180 degrees 1 or 2
Blanching at juncꢀon of anterior non-pigmented and pigmented TM

Endpoint

Bubble formaꢀon

Table 6 - Cyclophotocoagulaꢀon for Glaucoma: Internaꢀonal Recommendaꢀons

Treatment

  • Transscleral Nd: YAG Laser
  • Transscleral Diode Laser

Parameters

Laser Type

  • Nd: YAG Laser
  • Diode Laser

Power

  • 4 to 7 J
  • 1.0 to 2.5 W

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    Retinal Detachment with Subretinal and Vitreous Hemorrhages Causing Secondary Angle Closure Glaucoma Diagnosed with Ultrasound

    Henry Ford Health System Henry Ford Health System Scholarly Commons Emergency Medicine Articles Emergency Medicine 5-22-2020 Retinal detachment with subretinal and vitreous hemorrhages causing secondary angle closure glaucoma diagnosed with ultrasound Michael B. Holbrook Daniel Kaitis Lily Van Laere Jeffrey Van Laere Christopher R. Clark Follow this and additional works at: https://scholarlycommons.henryford.com/ emergencymedicine_articles YAJEM-159017; No of Pages 2 American Journal of Emergency Medicine xxx (xxxx) xxx Contents lists available at ScienceDirect American Journal of Emergency Medicine journal homepage: www.elsevier.com/locate/ajem Retinal detachment with subretinal and vitreous hemorrhages causing secondary angle closure glaucoma diagnosed with ultrasound Michael B. Holbrook, MD, MBA a,⁎, Daniel Kaitis, MD b, Lily Van Laere, MD b, Jeffrey Van Laere, MD, MPH a, Chris Clark, MD a a Henry Ford Hospital, Department of Emergency Medicine, Detroit, MI, United States of America b Henry Ford Hospital, Department of Ophthalmology, Detroit, MI, United States of America A 90-year-old female with a past medical history of trigeminal neu- choroid/retina consistent with a retinal detachment. Her pain was con- ralgia and age-related macular degeneration (AMD) presented with a trolled with oral hydrocodone/acetaminophen. Ultimately her vision four-day history of a left-sided headache, nausea, and vomiting. Regard- was deemed unsalvageable given her age, length of symptoms, and ing her left eye, she reported intermittent flashes of light over the past lack of light perception. At time of discharge, her left eye's IOP was month and complete vision loss for four days. She denied a history of di- 49 mmHg.
  • Guidelines for Universal Eye Screening in Newborns Including RETINOPATHY of Prematurity

    Guidelines for Universal Eye Screening in Newborns Including RETINOPATHY of Prematurity

    GUIDELINES FOR UNIVERSAL EYE SCREENING IN NEWBORNS INCLUDING RETINOPATHY OF PREMATURITY RASHTRIYA BAL SWASthYA KARYAKRAM Ministry of Health & Family Welfare Government of India June 2017 MESSAGE The Ministry of Health & Family Welfare, Government of India, under the National Health Mission launched the Rashtriya Bal Swasthya Karyakram (RBSK), an innovative and ambitious initiative, which envisages Child Health Screening and Early Intervention Services. The main focus of the RBSK program is to improve the quality of life of our children from the time of birth till 18 years through timely screening and early management of 4 ‘D’s namely Defects at birth, Development delays including disability, childhood Deficiencies and Diseases. To provide a healthy start to our newborns, RBSK screening begins at birth at delivery points through comprehensive screening of all newborns for various defects including eye and vision related problems. Some of these problems are present at birth like congenital cataract and some may present later like Retinopathy of prematurity which is found especially in preterm children and if missed, can lead to complete blindness. Early Newborn Eye examination is an integral part of RBSK comprehensive screening which would prevent childhood blindness and reduce visual and scholastic disabilities among children. Universal newborn eye screening at delivery points and at SNCUs provides a unique opportunity to identify and manage significant eye diseases in babies who would otherwise appear healthy to their parents. I wish that State and UTs would benefit from the ‘Guidelines for Universal Eye Screening in Newborns including Retinopathy of Prematurity’ and in supporting our future generation by providing them with disease free eyes and good quality vision to help them in their overall growth including scholastic achievement.
  • Tips and Techniques for Cataract Surgery in Glaucoma Patients

    Tips and Techniques for Cataract Surgery in Glaucoma Patients

    Tips and Techniques for Cataract Surgery in Glaucoma Patients Joey Yen-Cheng Hsia, MD Assistant Professor of Ophthalmology Glaucoma Service University of California, San Francisco No Financial Disclosures Introduction • Visually significant cataract often co-exist with glaucoma in the elderly population. • Glaucoma incisional surgery can lead to accelerated cataract formation. • Glaucoma patients are at risk for perioperative complications • Set realistic expectation preoperatively Preoperative Evaluation – Is the cataract or glaucoma causing the decreased vision? – PAP or PAM – Set realistic expectation – Is the IOP at target? – Role of combined surgery? – No. of medications – Anticoagulation – ⍺-1 blocker – Prior incisional surgeries Examination – angle grading, trab ostium - Prior incisional surgery - endothelial dysfunction – shallowing – dilation, prior LPI, iridectomy – PXE, phacodynesis – cupping, pallor, retinal pathology Postoperative IOP Spike • Note the of glaucoma – Foveal involving scotoma – At risk for progression with IOP spike : – Advanced glaucoma, IFIS, No. of gtts, long AXL, PXE • IOP spike occurs after surgery – Same day check up for high risk patients History of Trabeculectomy – Modify incisions accordingly – Avoid suction / fixation ring – High function bleb may lead to chemosis / chamber instability – Age<50, Preop IOP > 10, iris manipulation, postop IOP spike, and short interval time between trabeculectomy and cataract – Longer steroid +/- anti- metabolite Grover-Fellman spatula; Epislon History of Tube Shunt –
  • Extended Long-Term Outcomes of Penetrating Keratoplasty for Keratoconus

    Extended Long-Term Outcomes of Penetrating Keratoplasty for Keratoconus

    Extended Long-term Outcomes of Penetrating Keratoplasty for Keratoconus Sudeep Pramanik, MD, MBA,1 David C. Musch, PhD, MPH,2 John E. Sutphin, MD,1 Ayad A. Farjo, MD1,3,4 Objective: To report graft survival results for initial penetrating keratoplasty (PK) performed more than 20 years ago for keratoconus. Secondary outcome measures included recurrent keratoconus, best spectacle- corrected visual acuity (BSCVA), and rates of glaucoma. Design: Retrospective, consecutive, noncomparative case series. Participants: All patients with clinical and histopathological keratoconus who underwent initial PK at the University of Iowa Hospitals and Clinics from 1970 to 1983. Patients with pellucid marginal degeneration were excluded. Methods: At baseline, age, preoperative BSCVA, keratometric astigmatism, and host/donor graft sizes for each eye were recorded. Visual acuity and intraocular pressure were followed until the eyes reached 1 of 4 end points: graft failure, recurrent keratoconus, loss to follow-up, or death. Kaplan–Meier survival analysis was performed to estimate the long-term probability of graft failure and recurrent keratoconus. Results: Among the 112 eyes of 84 patients who met entry criteria, there was a mean age at transplant of 33.7 years and preoperative BSCVA of 20/193. With a mean follow-up of 13.8 years (range, 0.5–30.4), 7 eyes (6.3%) experienced graft failure. Recurrent keratoconus was confirmed clinically or histologically in 6 eyes (5.4%), with a mean time to recurrence of 17.9 years (range, 11–27). Kaplan–Meier analysis estimated a graft survival rate of 85.4% and a rate of recurrent keratoconus of 11.7% at 25 years after initial transplantation.
  • Understanding and Living with Glaucoma

    Understanding and Living with Glaucoma

    Understanding and Living with Glaucoma Betty hopes future generations won’t have to live with glaucoma. Dr. Goldberg’s breakthrough research could mean they won’t have to. Understanding and Living with Glaucoma C SUPPORTED BY AN EDUCATIONAL GRANT FROM AERIE PHARMACEUTICALS, INC. Glaucoma is an eye disease that gradually steals your vision. Usually, glaucoma has no symptoms in its early stages. But without proper treatment glaucoma can lead to blindness. The good news is that with regular eye exams, early detection, and treatment, you can preserve your sight. This guide will give you a complete introduction to the facts about glaucoma. D Glaucoma Research Foundation 2 INTRODUCTION 3 UNDERSTANDING GLAUCOMA 3 Understand the Eye to Understand Glaucoma 4 How Glaucoma Affects the Eye 6 Who Gets Glaucoma? 7 Are There Symptoms? 7 When Should You Get Your Eyes Checked for Glaucoma? 8 DIFFERENT TYPES OF GLAUCOMA 8 Primary Open-Angle or Open-Angle Glaucoma 9 Primary Angle-Closure or Angle-Closure Glaucoma or Narrow-Angle Glaucoma 10 Other Types of Glaucoma 10 • Normal-Tension Glaucoma 10 • Secondary Glaucoma 12 DETECTING GLAUCOMA 12 How Is Glaucoma Diagnosed? 12 What To Expect During Glaucoma Examinations 12 • Tonometry 12 • Ophthalmoscopy 15 • Perimetry 16 • Gonioscopy 16 • Pachymetry 17 TREATING GLAUCOMA 17 Treatment of Primary Open-Angle Glaucoma 17 • Selective Laser Trabeculoplasty 18 • Glaucoma Medications 21 • Incisional Surgeries 25 • Unapproved Treatments 25 Treatment of Primary Angle-Closure Glaucoma 26 Treatment of Other Types of Glaucoma 28 FREQUENTLY ASKED QUESTIONS 30 LIVING WITH GLAUCOMA 30 Working with Your Doctor 32 Responding to Vision Changes Due to Glaucoma 32 Questions For Your Doctor 34 Your Lifestyle Counts 35 Looking Ahead 36 APPENDIX 36 A Guide To Glaucoma Medications 38 Glossary Understanding and Living with Glaucoma 1 Introduction If you have been diagnosed with glaucoma, or are a glaucoma suspect, you probably have a lot of questions and some concerns.
  • Understanding-Glaucoma.Pdf

    Understanding-Glaucoma.Pdf

    Understanding Glaucoma National Glaucoma Research Understanding Glaucoma through its built-in drainage pathway. Then What is Glaucoma? the aqueous humor flows out through a Glaucoma is not just one disease, but a spongy tissue at the front of the eye called the group of eye diseases that damage the optic trabecular meshwork, into a drainage canal. nerve—the bundle of nerve fibers that carries In the more common forms of glaucoma, information from the eye to the brain. fluid cannot flow effectively through the trabecular meshwork, causing an increase in More than 60 million people around the IOP. This compresses the back of the eye and globe have glaucoma. In the United States, an is associated with damage to the optic nerve, estimated 3 million people have the disease, leading to vision loss. but as many as half of them may not even know it. There are additional types of glaucoma where optic nerve damage may occur The most common types of glaucoma often even with normal IOP. have no symptoms until irreversible damage to the eye has already occurred and vision loss has begun. That’s why glaucoma is sometimes called the “sneak thief of sight,” and why regular Types of Glaucoma screening and early detection are so important & Risk Factors in glaucoma. Some of the risk factors for glaucoma, such as, eye pressure and the condition of your cornea and optic nerve, are things you won’t know unless you’ve seen an eye doctor. That’s why it’s important to get comprehensive dilated eye exams on a regular basis, starting at the right age for your risk category.