EXHIBIT a – TEST NAME DESCRIPTIONS Item Test Name Description No

Total Page:16

File Type:pdf, Size:1020Kb

EXHIBIT a – TEST NAME DESCRIPTIONS Item Test Name Description No EXHIBIT A – TEST NAME DESCRIPTIONS Item Test Name Description No. 1. Postmortem, Basic, Blood 11-Hydroxy Delta-9 THC, 6-Monoacetylmorphine – Free, 7-Amino Clonazepam, Acetone, Acetyl Fentanyl, Alpha-Hydroxyalprazolam, Alprazolam, Amobarbital, Amphetamine, Amphetamines, Barbiturates, Benzodiazepines, Benzoylecgonine, Blood Alcohol Concentration (BAC), Buprenorphine – Free, Buprenorphine / Metabolite, Butabarbital, Butalbital, Cannabinoids, Chlordiazepoxide, Clobazam, Clonazepam, Cocaethylene, Cocaine, Cocaine / Metabolites, Codeine – Free, Delta-9 Carboxy THC, Delta-9 THC Desalkylflurazepam, Diazepam, Dihydrocodeine / Hydrocodol – Free, EDDP, Ephedrine, Estazolam, Ethanol, Fentanyl, Fentanyl / Acetyl Fentanyl, Flurazepam, Hydrocodone – Free, Hydromorphone – Free, Hydroxyethylflurazepam, Hydroxytriazolam, Isopropanol, Lorazepam, MDA, MDEA, MDMA, Methadone, Methadone / Metabolite, Methamphetamine, Methamphetamine / MDMA, Methanol, Midazolam, Morphine - Free, Norbuprenorphine - Free, Nordiazepam, Norfentanyl, Norpseudoephedrine, Opiates, Oxazepam, Oxycodone - Free, Oxycodone / Oxymorphone, Pentobarbital, Phencyclidine, Phenobarbital,Phentermine, Phenylpropanolamine, Pseudoephedrine, Secobarbital, Temazepam, Triazolam 2. Postmortem, Basic, Tissue 11-Hydroxy Delta-9 THC, 6-Monoacetylmorphine – Free, 7-Amino Clonazepam, Acetone, Acetyl Fentanyl, Alpha-Hydroxyalprazolam, Alprazolam, Amobarbital, Amphetamine, Amphetamines, Barbiturates, Benzodiazepines, Benzoylecgonine, Blood Alcohol Concentration (BAC), Buprenorphine – Free, Buprenorphine / Metabolite, Butobarbital, Butalbital, Cannabinoids, Chlordiazepoxide, Clobazam, Clonazepam, Cocaethylene, Cocaine, Cocaine / Metabolites, Codeine – Free, Delta-9 Carboxy THC, Delta-9 THC Desalkylflurazepam, Diazepam, Dihydrocodeine / Hydrocodol – Free, EDDP, Ephedrine, Estazolam, Ethanol, Fentanyl, Fentanyl / Acetyl Fentanyl, Flurazepam, Hydrocodone – Free, Hydromorphone – Free, Hydroxyethylflurazepam, Hydroxytriazolam, Isopropanol, Lorazepam, MDA, MDEA, MDMA, Methadone, Methadone / Metabolite, Methamphetamine, Methamphetamine / MDMA, Methanol, Midazolam, Morphine - Free, Norbuprenorphine - Free, Nordiazepam, Norfentanyl, Norpseudoephedrine, Opiates, Oxazepam, Oxycodone - Free, Oxycodone / Oxymorphone, Pentobarbital, Phencyclidine, Phenobarbital, Phentermine, Phenylpropanolamine, Pseudoephedrine, Secobarbital, Temazepam, Triazolam 3. Postmortem, Basic, Fluid 11-Hydroxy Delta-9 THC, 6-Monoacetylmorphine – Free, 7-Amino Clonazepam, Acetone, Acetyl Fentanyl, Alpha-Hydroxyalprazolam, Alprazolam, Amobarbital, Amphetamine, Amphetamines, Barbiturates, Benzodiazepines, Benzoylecgonine, Blood Alcohol Concentration (BAC), Buprenorphine – Free, Buprenorphine / Metabolite, Butobarbital, Butalbital, Cannabinoids, Chlordiazepoxide, Clobazam, Clonazepam, Cocaethylene, Cocaine, Cocaine / Metabolites, Codeine – Free, Delta-9 Carboxy THC, Delta-9 THC Desalkylflurazepam, Diazepam, Dihydrocodeine / Hydrocodol – Free, EDDP, Ephedrine, Estazolam, Ethanol, Fentanyl, Fentanyl / Acetyl Fentanyl, Flurazepam, Hydrocodone – Free, Hydromorphone – Free, Hydroxyethylflurazepam, Hydroxytriazolam, Isopropanol, Lorazepam, MDA, MDEA, MDMA, Methadone, Methadone / Metabolite, Methamphetamine, Methamphetamine / MDMA, Methanol, Midazolam, Morphine - Free, Norbuprenorphine - Free, Nordiazepam, Norfentanyl, Norpseudoephedrine, Opiates, Oxazepam, Oxycodone - Free, Oxycodone / Oxymorphone, Pentobarbital, Phencyclidine, Phenobarbital, Phentermine, Phenylpropanolamine, Pseudoephedrine, Secobarbital, Temazepam, Triazolam 4 Postmortem, Expanded, Blood 10-Hydroxycarbazepin, 11-Hydroxy Delta-9 THC, 2-Furanylfentanyl, 6-Beta-Naltrexol – Free, 6- Monoacetylmorphine, 6-Monoacetylmorphine – Free, 7-Amino Clonazepam, 7-Amino Flunitrazepam, 9-Hydroxyrisperidone, Acetaminophen, Acetone, Acetyl Fentanyl, Acryl Fentanyl, Alfentanil, Alpha- Hydroxyalprazolam, Alprazolam, Amitriptyline, Amobarbital, Amoxapine, Amphetamine, Aripiprazole, Atomoxetine, Atropine, BZP, Barbiturates, Benzoylecgonine, Benztropine, Blood Alcohol Concentration (BAC), Bromazepam, Brompheniramine, Bupivacaine, Buprenorphine, Buprenorphine – Free, Bupropion, Buspirone, Butabarbital, Butalbital, Butorphanol, Butorphanol – Free, Butylone, Butyrylfentanyl, Caffeine, Cannabinoids, Carbamazepine, Carbamazepine-10,11 – Epoxide, Carfentanil, Carisoprodol, Chlordiazepoxide, Chlorpheniramine, Chlorpromazine, Citalopram / Escitalopram, Clobazam, Clomipramine, Clonazepam, Clonazolam, Clonidine, Clozapine, Cocaethylene, Cocaine, Codeine, Cotinine, Cyclobenzaprine, Cyclopropylfentanyl, Delorazepam, Delta-9 Carboxy THC, Delta-9 THC, Desalkylflurazepam, Desethyl Vardenafil, Desipramine, Desmethylclomipramine, Desmethyldoxepin, Desmethylloperamide, Desmethylsertraline, Desmethyltrimipramine, Dextro / Levo Methorphan, Dextrorphan / Levorphanol, Diazepam, Dibutylone, Diclazepam, Dicyclomine, Dihydrocodeine / Hydrocodol, Dihydrocodeine / Hydrocodol – Free, Diltiazem, Diphenhydramine, Donepezil, Doxepin, Doxylamine, Duloxetine, EDDP, Ephedrine, Estazolam, Eszopiclone / Zopiclone, Ethanol, Etizolam, Etomidate, Fentanyl, Flecainide, Flubromazepam, Flubromazolam, Flunitrazepam, Fluoxetine, Fluphenazine, Flurazepam, Fluvoxamine, Gabapentin, Glimepiride, Glipizide, Glyburide, Guaifenesin, Haloperidol, Hydrocodone, Hydrocodone – Free, Hydromorphone, Hydromorphone – Free, Hydroxybupropion, Hydroxyethylflurazepam, Hydroxytriazolam, Hydroxyzine, Iloperidone, Imipramine, Isobutyrylfentanyl, Isopropanol, Itraconazol, Ketamine, Ketoconazole, LSD, Lacosamide, Lamotrigine, Laudanosine, Levamisole, Levetiracetam, Lidocaine, Loperamide, Lorazepam, Loxapine, MDA, MDEA, MDMA, Maprotiline, Memantine, Meperidine, Meprobamate, Mescaline, Mesoridazine, Metaxalone, Methadone, Methamphetamine, Methanol, Methaqualone, Methocarbamol, Methoxyacetylfentanyl, Methylphenidate, Metoclopramide, Metoprolol, Mexiletine, Midazolam, Mirtazapine, Mitragynine, Monoethylglycinexylidide (MEGX), Morphine, Morphine - Free, N-Desmethylsildenafil, N-Ethyl Pentylone, Nalbuphine, Nalbuphine - Free, Naloxone, Naltrexone, Naltrexone - Free, Naproxen, Nicotine, Nifedipine, Norbuprenorphine - Free, Norclozapine, Nordiazepam, Norfentanyl, Norflunitrazepam, Norfluoxetine, Norketamine, Normeperidine, Norpropoxyphene, Norpseudoephedrine, Nortriptyline, O-Desmethyltramadol, O-Desmethylvenlafaxine, Olanzapine, Orphenadrine, Oxazepam, Oxycodone, Oxycodone - Free, Oxymorphone, Oxymorphone - Free, Paroxetine, Pentobarbital, Perphenazine, Phenazepam, Phencyclidine, Pheniramine, Phenobarbital, Phentermine, Phenylethylmalonamide (PEMA), Phenylpropanolamine, Phenytoin, Primidone, Prochlorperazine, Promazine, Promethazine, Propoxyphene, Pseudoephedrine, Psilocin, Quetiapine, Quinidine, Quinine, Risperidone, Risperidone and 9-Hydroxyrisperidone - Total, Ritalinic Acid, Salicylate, Salicylates, Scope Statement, Secobarbital, Sertraline, Sildenafil, Strychnine, Sufentanil, TFMPP, Tadalafil, Tapentadol, Tapentadol - Free, Temazepam, Tetrahydrozoline, Theophylline, Thioridazine, Tiletamine, Topiramate, Tramadol, Trazodone, Triazolam, Trifluoperazine, Trihexyphenidyl, Trimipramine, Triprolidine, U-47700, Valeryl Fentanyl, Vardenafil, Venlafaxine, Verapamil, Voriconazole, Warfarin, Xylazine, Yohimbine, Zaleplon, Ziprasidone, Zolazepam, Zolpidem, Zonisamide, cis-3-Methlyfentanyl, mCPP, para-Fluor butyryl Fentanyl, para-Fluoroisobutyryl Fentanyl, trans-2-Methylfentanyl EXHIBIT A – TEST NAME DESCRIPTIONS 5. Postmortem, Expanded, Tissue 10-Hydroxycarbazepin, 11-Hydroxy Delta-9 THC, 2-Furanylfentanyl, 6-Beta-Naltrexol – Free, 6- Monoacetylmorphine, 6-Monoacetylmorphine – Free, 7-Amino Clonazepam, 7-Amino Flunitrazepam, 9-Hydroxyrisperidone, Acetaminophen, Acetone, Acetyl Fentanyl, Acryl Fentanyl, Alfentanil, Alpha- Hydroxyalprazolam, Alprazolam, Amitriptyline, Amobarbital, Amoxapine, Amphetamine, Aripiprazole, Atomoxetine, Atropine, BZP, Barbiturates, Benzoylecgonine, Benztropine, Blood Alcohol Concentration (BAC), Bromazepam, Brompheniramine, Bupivacaine, Buprenorphine, Buprenorphine – Free, Bupropion, Buspirone, Butabarbital, Butalbital, Butorphanol, Butorphanol – Free, Butylone, Butyrylfentanyl, Caffeine, Cannabinoids, Carbamazepine, Carbamazepine-10,11 – Epoxide, Carfentanil, Carisoprodol, Chlordiazepoxide, Chlorpheniramine, Chlorpromazine, Citalopram / Escitalopram, Clobazam, Clomipramine, Clonazepam, Clonazolam, Clonidine, Clozapine, Cocaethylene, Cocaine, Codeine, Cotinine, Cyclobenzaprine, Cyclopropylfentanyl, Delorazepam, Delta-9 Carboxy THC, Delta-9 THC, Desalkylflurazepam, Desethyl Vardenafil, Desipramine, Desmethylclomipramine, Desmethyldoxepin, Desmethylloperamide, Desmethylsertraline, Desmethyltrimipramine, Dextro / Levo Methorphan, Dextrorphan / Levorphanol, Diazepam, Dibutylone, Diclazepam, Dicyclomine, Dihydrocodeine / Hydrocodol, Dihydrocodeine / Hydrocodol – Free, Diltiazem, Diphenhydramine, Donepezil, Doxepin, Doxylamine, Duloxetine, EDDP, Ephedrine, Estazolam, Eszopiclone / Zopiclone, Ethanol, Etizolam, Etomidate, Fentanyl, Flecainide, Flubromazepam, Flubromazolam, Flunitrazepam, Fluoxetine, Fluphenazine, Flurazepam, Fluvoxamine, Gabapentin, Glimepiride, Glipizide, Glyburide, Guaifenesin, Haloperidol, Hydrocodone, Hydrocodone – Free, Hydromorphone, Hydromorphone – Free, Hydroxybupropion, Hydroxyethylflurazepam, Hydroxytriazolam, Hydroxyzine, Iloperidone, Imipramine, Isobutyrylfentanyl, Isopropanol, Itraconazol, Ketamine, Ketoconazole, LSD, Lacosamide, Lamotrigine, Laudanosine, Levamisole, Levetiracetam, Lidocaine, Loperamide, Lorazepam, Loxapine, MDA,
Recommended publications
  • 18 December 2020 – to Date)
    (18 December 2020 – to date) MEDICINES AND RELATED SUBSTANCES ACT 101 OF 1965 (Gazette No. 1171, Notice No. 1002 dated 7 July 1965. Commencement date: 1 April 1966 [Proc. No. 94, Gazette No. 1413] SCHEDULES Government Notice 935 in Government Gazette 31387 dated 5 September 2008. Commencement date: 5 September 2008. As amended by: Government Notice R1230 in Government Gazette 32838 dated 31 December 2009. Commencement date: 31 December 2009. Government Notice R227 in Government Gazette 35149 dated 15 March 2012. Commencement date: 15 March 2012. Government Notice R674 in Government Gazette 36827 dated 13 September 2013. Commencement date: 13 September 2013. Government Notice R690 in Government Gazette 36850 dated 20 September 2013. Commencement date: 20 September 2013. Government Notice R104 in Government Gazette 37318 dated 11 February 2014. Commencement date: 11 February 2014. Government Notice R352 in Government Gazette 37622 dated 8 May 2014. Commencement date: 8 May 2014. Government Notice R234 in Government Gazette 38586 dated 20 March 2015. Commencement date: 20 March 2015. Government Notice 254 in Government Gazette 39815 dated 15 March 2016. Commencement date: 15 March 2016. Government Notice 620 in Government Gazette 40041 dated 3 June 2016. Commencement date: 3 June 2016. Prepared by: Page 2 of 199 Government Notice 748 in Government Gazette 41009 dated 28 July 2017. Commencement date: 28 July 2017. Government Notice 1261 in Government Gazette 41256 dated 17 November 2017. Commencement date: 17 November 2017. Government Notice R1098 in Government Gazette 41971 dated 12 October 2018. Commencement date: 12 October 2018. Government Notice R1262 in Government Gazette 42052 dated 23 November 2018.
    [Show full text]
  • Seminar on Drug Chirality
    Drug chirality: Stereoselectivity in the action and disposition of anaesthetic agents Isomerism Isomers: Drugs with the same chemical composition and molecular formula. Isomers Structural Stereoisomers isomers •Constitutional / Structural isomerism: Same molecular formula but different chemical structure as the arrangement of atoms is different. Stereoisomerism: Same molecular formula and chemical structure but a different configuration (i.e. different three dimensional spatial arrangement of their atoms) Two types: 1. Optical isomers 2. Geometrical isomers Optical isomerism Enantiomers: A pair of stereoisomers that are non-superimposable mirror images of each other. Cause of enantiomerism: presence of a chiral centre. Physiochemical properties ( solubility, melting and boiling points, ionization constant) are identical. Separation is difficult. Diastereomers: Stereoisomers that are not mirror images of each other and are not enantiomeric. Physiochemical properties are different. Separation is easy. What is chirality? Chiral - derived from a Greek word chiros, meaning handedness. A molecule or object that is not superimposable on its mirror image is said to be chiral. Chiral centre / asymmetric carbon / stereogenic centre – A carbon atom attached to four different substituents. • Achiral molecules usually contain a plane of symmetry but chiral molecules do not. • A plane of symmetry is a mirror plane that cuts the molecule in half, so that one half of the molecule is a reflection of the other half. • With chiral compounds, the plane of the polarized light is rotated through an angle . A compound that rotates polarized light is said to be optically active. •With achiral compounds, the light that passes through the compound remains unchanged. A compound that does not change the plane of polarized light is said to be optically inactive.
    [Show full text]
  • Consensus for the Management of Analgesia, Sedation and Delirium in Adults with COVID-19-Associated Acute Respiratory Distress Syndrome
    ARTIGO ESPECIAL Manuel Donato1,2,3 , Federico Carlos Carini4 , María Julia Meschini5, Ignacio López Saubidet6 , Consenso para el manejo de la analgesia, sedación Adela Goldberg7, Marisol García Sarubio5, Daniela Olmos8, Rosa Reina5 em nombre del Comité de y delirium en adultos con síndrome de distrés Analgesia, Sedación y Delirium de la Sociedad Argentina de Terapia Intensiva respiratorio agudo por COVID-19 Consensus for the management of analgesia, sedation and delirium in adults with COVID-19-associated acute respiratory distress syndrome 1. Hospital General de Agudos José María Penna RESUMEN Sedación y Delirium de la Sociedad - Buenos Aires, Argentina. Argentina de Terapia Intensiva. 2. Ministerio de Salud de la Nación Argentina – Objetivo: Proponer estrategias Resultados: Se acordaron Buenos Aires, Argentina. agile para este abordaje integral de 3. Instituto de Efectividad Clínica y Sanitaria - recomendaciones y se desarrollaron la analgesia, sedación, delirium, Buenos Aires, Argentina. herramientas para asegurar un 4. Hospital Italiano de Buenos Aires - Buenos implementación de movilidad abordaje integral de analgesia, Aires, Argentina. temprana e inclusión familiar del sedación, delirium, implementación 5. Hospital Interzonal General de Agudos General paciente con síndrome de dificultad San Martín - La Plata, Argentina. de movilidad temprana e inclusión respiratoria aguda por COVID-19, 6. Centro de Educación Médica e Investigaciones familiar del paciente adulto con Clínicas “Norberto Quirno” - Buenos Aires, Argentina. considerando el alto riesgo de infección síndrome de dificultad respiratoria 7. Sanatorio de La Trinidad Mitre - Buenos Aires, que existe entre los trabajadores de Argentina. aguda por COVID-19. salud, el tratamiento humanitario 8. Hospital Municipal Príncipe de Asturias - Córdoba, Discusión: Ante el nuevo orden Argentina.
    [Show full text]
  • Recommended Methods for the Identification and Analysis of Fentanyl and Its Analogues in Biological Specimens
    Recommended methods for the Identification and Analysis of Fentanyl and its Analogues in Biological Specimens MANUAL FOR USE BY NATIONAL DRUG ANALYSIS LABORATORIES Laboratory and Scientific Section UNITED NATIONS OFFICE ON DRUGS AND CRIME Vienna Recommended Methods for the Identification and Analysis of Fentanyl and its Analogues in Biological Specimens MANUAL FOR USE BY NATIONAL DRUG ANALYSIS LABORATORIES UNITED NATIONS Vienna, 2017 Note Operating and experimental conditions are reproduced from the original reference materials, including unpublished methods, validated and used in selected national laboratories as per the list of references. A number of alternative conditions and substitution of named commercial products may provide comparable results in many cases. However, any modification has to be validated before it is integrated into laboratory routines. ST/NAR/53 Original language: English © United Nations, November 2017. All rights reserved. The designations employed and the presentation of material in this publication do not imply the expression of any opinion whatsoever on the part of the Secretariat of the United Nations concerning the legal status of any country, territory, city or area, or of its authorities, or concerning the delimitation of its frontiers or boundaries. Mention of names of firms and commercial products does not imply the endorse- ment of the United Nations. This publication has not been formally edited. Publishing production: English, Publishing and Library Section, United Nations Office at Vienna. Acknowledgements The Laboratory and Scientific Section of the UNODC (LSS, headed by Dr. Justice Tettey) wishes to express its appreciation and thanks to Dr. Barry Logan, Center for Forensic Science Research and Education, at the Fredric Rieders Family Founda- tion and NMS Labs, United States; Amanda L.A.
    [Show full text]
  • Understanding and Challenging the Drugs: Chemistry and Toxicology
    UNDERSTANDING AND CHALLENGING THE DRUGS: CHEMISTRY AND TOXICOLOGY Presenter: • Dr. Jasmine Drake, Graduate Program Director and Assistant Professor, Administration of Justice Department, Barbara Jordan-Mickey Leland School of Public Affairs, Texas Southern University NACDL Training Defending Drug Overdose Homicides in Pennsylvania Penn State Harrisburg, Middletown, PA November 6th, 2019 11:30- 12:45 p.m. Understanding & Challenging the Drugs: Chemistry & Toxicology Dr. Jasmine Drake, Forensic Science Learning Laboratory, Texas Southern University I. Opioid Drug Classifications A. Types of Opioids B. Classic vs. Synthetic C. Toxicology of Opioids 1) How opioids interact with the body 2) Addiction (psychological vs. physiological II. New Classes of Drugs A. Emerging Threats B. Potency III. National Trends in Opioid Overdose Deaths in the U.S. A. Based on State B. Ethnicity C. Drug-Type (prescription vs. fentanyl vs. heroin) IV. Trends of Opioid Overdose Deaths in Philadelphia A. Based on Ethnicity B. Drug Type (prescription vs. fentanyl vs. heroin) V. Legal Considerations to the Opioid Epidemic A. Punitive Measures vs. Rehabilitative Treatment B. Progressive Jurisdictions Nationwide C. New Legal Measures in Philadelphia VI. Toxicology Reports A. What’s in the report? B. Key Aspects of the Tox Report C. Terminology D. Evaluating and Interpreting the data? E. Questions and considerations. VII. Conclusion and Discussion A. Case Specific Examples B. Sample Toxicology Reports The Opioid Epidemic: What labs have to do with it? Ewa King, Ph.D. Associate Director of Health RIDOH State Health Laboratories Analysis. Answers. Action. www.aphl.org Overview • Overdose trends • Opioids and their effects • Analytical testing approaches • Toxicology laboratories Analysis. Answers. Action.
    [Show full text]
  • Smumedical Journal
    SMU Medical Journal ISSN : 2349 – 1604 (Volume – 4, No. 1, January 2017) Review Article Indexed in SIS (USA), ASI (Germany), I2OR & i-Scholar (India), SJIF (Morocco) and Cosmos Foundation (Germany) databases. Impact Factor: 3.835 (SJIF) Analytical Aspects with Brief Overview of Depressants Sandeep Kumar1 Nand Gopal Giri2 Ashok Kumar Jaiswal3* Anil Kumar Jaiswal4 1M.Sc. (Forensic Science), LNJN NICFS, New Delhi 110085, 2Assistant Professor, Department of Chemistry, Shivaji College (University of Delhi) Raja Garden, New Delhi 110 027, 3Dept. of Forensic Medicine and toxicology, All India institute of Medical Sciences, New Delhi 110 029.4Assistant Professor, Department of Mathematics, St. Andrew’s PG College, Gorakhpur, UP. *Corresponding author Manuscript received : 30.10.2016 Manuscript accepted: 21.11.2016 Abstract Depressants are drugs that slow down the functions of the central nervous system (CNS). These drugs are used to reduce anxiety and insomnia without drowsiness. The depressants cause relaxed feeling if used in small quantity but cause unconsciousness, vomiting and even death if taken in high quantity. It affects concentration and coordination of a person by slowing down his/ her ability to respond in unexpected situations. These drugs are also attributed for their physiological and psychological effects, eventually in large dose it become lethal. The different 142 SMU Medical Journal, Volume – 4, No. – 1, January, 2017 physical and chemical features of some very often used depressants are discussed in this manuscript. Keyword: Depressant, TLC, UV spectroscopy, HPLC, GLC etc. Introduction The classical depressants are hypnotics (which induce sleep), most antianxiety medicine (diazepam or valium), muscle spasm prevent seizure, but these drugs rapidly develop dependence and tolerance which finally leads to coma and death, so use of these drugs is highly unsafe.
    [Show full text]
  • CAS Number Index
    2334 CAS Number Index CAS # Page Name CAS # Page Name CAS # Page Name 50-00-0 905 Formaldehyde 56-81-5 967 Glycerol 61-90-5 1135 Leucine 50-02-2 596 Dexamethasone 56-85-9 963 Glutamine 62-44-2 1640 Phenacetin 50-06-6 1654 Phenobarbital 57-00-1 514 Creatine 62-46-4 1166 α-Lipoic acid 50-11-3 1288 Metharbital 57-22-7 2229 Vincristine 62-53-3 131 Aniline 50-12-4 1245 Mephenytoin 57-24-9 1950 Strychnine 62-73-7 626 Dichlorvos 50-23-7 1017 Hydrocortisone 57-27-2 1428 Morphine 63-05-8 127 Androstenedione 50-24-8 1739 Prednisolone 57-41-0 1672 Phenytoin 63-25-2 335 Carbaryl 50-29-3 569 DDT 57-42-1 1239 Meperidine 63-75-2 142 Arecoline 50-33-9 1666 Phenylbutazone 57-43-2 108 Amobarbital 64-04-0 1648 Phenethylamine 50-34-0 1770 Propantheline bromide 57-44-3 191 Barbital 64-13-1 1308 p-Methoxyamphetamine 50-35-1 2054 Thalidomide 57-47-6 1683 Physostigmine 64-17-5 784 Ethanol 50-36-2 497 Cocaine 57-53-4 1249 Meprobamate 64-18-6 909 Formic acid 50-37-3 1197 Lysergic acid diethylamide 57-55-6 1782 Propylene glycol 64-77-7 2104 Tolbutamide 50-44-2 1253 6-Mercaptopurine 57-66-9 1751 Probenecid 64-86-8 506 Colchicine 50-47-5 589 Desipramine 57-74-9 398 Chlordane 65-23-6 1802 Pyridoxine 50-48-6 103 Amitriptyline 57-92-1 1947 Streptomycin 65-29-2 931 Gallamine 50-49-7 1053 Imipramine 57-94-3 2179 Tubocurarine chloride 65-45-2 1888 Salicylamide 50-52-2 2071 Thioridazine 57-96-5 1966 Sulfinpyrazone 65-49-6 98 p-Aminosalicylic acid 50-53-3 426 Chlorpromazine 58-00-4 138 Apomorphine 66-76-2 632 Dicumarol 50-55-5 1841 Reserpine 58-05-9 1136 Leucovorin 66-79-5
    [Show full text]
  • UCSF UC San Francisco Previously Published Works
    UCSF UC San Francisco Previously Published Works Title Fentanyl, fentanyl analogs and novel synthetic opioids: A comprehensive review Permalink https://escholarship.org/uc/item/8xh0s7nf Authors Armenian, Patil Vo, Kathy Barr-Walker, Jill et al. Publication Date 2017-10-01 Peer reviewed eScholarship.org Powered by the California Digital Library University of California Fentanyl, fentanyl analogs and novel synthetic opioids: A comprehensive review Patil Armenian, Kathy Vo, Jill Barr-Walker, Kara Lynch University of California, San Francisco-Fresno and University of California, San Francisco Keywords: opioid, synthetic opioids, fentanyl, fentanyl analog, carfentanil, naloxone Abbreviations: 4-ANPP: 4-anilino-N-phenethyl-4-piperidine; ANPP 4Cl-iBF: 4-chloroisobutyryfentanyl 4F-iBF: 4-fluoroisobutyrfentanyl AEI: Advanced electronic information AMF: alpha-methylfentanyl CBP: US Customs and Border Protection CDC: Centers for Disease Control CDSA: Controlled Drug and Substance Act (Canada) CNS: central nervous system DEA: US Drug Enforcement Agency DTO: Drug trafficking organization ED: Emergency department ELISA: enzyme-linked immunosorbent assay EMCDDA: European Monitoring Centre for Drug and Drug Addiction FDA: US Food and Drug Administration GC-MS: gas chromatography mass spectrometry ICU: intensive care unit IN: intranasal IV: intravenous LC-HRMS: liquid chromatography high resolution mass spectrometry LC-MS/MS: liquid chromatography tandem mass spectrometry MDA: United Kingdom Misuse of Drugs Act NPF: non-pharmaceutical fentanyl THF-F: tetrahydrofuranfentanyl US: United States USPS: US Postal Service UNODC: United Nations office on drugs and crime 1. Introduction The death rate due to opioid analgesics nearly quadrupled in the US from 1999 to 2011 and was responsible for 33,091 deaths in 2015 (CDC, 2014; Rudd et al., 2016).
    [Show full text]
  • Test Summary Sheet For
    Test Summary Sheet for: 8054B Postmortem, Expanded with NPS, Blood (Forensic) The following test codes are contained in this document: 1. 8054B Postmortem, Expanded with NPS, Blood (Forensic) 2. 50000B Acetaminophen Confirmation, Blood (Forensic) 3. 52250B Alcohols and Acetone Confirmation, Blood (Forensic) 4. 52143B Alfentanil and Sufentanil Confirmation, Blood (Forensic) 5. 52168B Amitriptyline and Metabolite Confirmation, Blood (Forensic) 6. 52239B Amoxapine Confirmation, Blood (Forensic) 7. 52485B Amphetamines Confirmation, Blood (Forensic) 8. 52416B Aripiprazole Confirmation, Blood (Forensic) 9. 52007B Atomoxetine Confirmation, Blood (Forensic) 10. 50011B Barbiturates Confirmation, Blood (Forensic) 11. 52365B Bath Salts Confirmation, Blood (Forensic) 12. 52367B Bath Salts Confirmation, Blood (Forensic) 13. 50012B Benzodiazepines Confirmation, Blood (Forensic) 14. 52443B Benztropine Confirmation, Blood (Forensic) 15. 52245B Brompheniramine Confirmation, Blood (Forensic) 16. 52011B Bupivacaine Confirmation, Blood (Forensic) 17. 52012B Bupropion and Metabolite Confirmation, Blood (Forensic) 18. 52444B Buspirone Confirmation, Blood (Forensic) 19. 52198B Cannabinoids Confirmation, Blood (Forensic) 20. 52015B Carbamazepine and Metabolite Confirmation, Blood (Forensic) 21. 52017B Carisoprodol and Metabolite Confirmation, Blood (Forensic) 22. 52440B Chlorpheniramine Confirmation, Blood (Forensic) 23. 52272B Chlorpromazine Confirmation, Blood (Forensic) 24. 52482B Citalopram Confirmation, Blood (Forensic) 25. 52274B Clomipramine and Metabolite
    [Show full text]
  • Comprehensive Multi-Analytical Screening Of
    COMPREHENSIVE MULTI-ANALYTICAL SCREENING OF DRUGS OF ABUSE, INCLUDING NEW PSYCHOACTIVE SUBSTANCES, IN URINE WITH BIOCHIP ARRAYS APPLIED TO THE EVIDENCE ANALYSER Darragh J., Keery L., Keenan R., Stevenson C., Norney G., Benchikh M.E., Rodríguez M.L., McConnell R. I., FitzGerald S.P. Randox Toxicology Ltd., Crumlin, United Kingdom e-mail: [email protected] Introduction Biochip array technology allows the simultaneous detection of multiple drugs from a single undivided sample, which This study summarises the analytical performance of three different biochip arrays applied to the screening of increases the screening capacity and the result output per sample. Polydrug consumption can be detected and by acetylfentanyl, AH-7921, amphetamine, barbiturates, benzodiazepines (including etizolam and clonazepam), incorporating new immunoassays on the biochip surface, this technology has the capacity to adapt to the new trends benzoylecgonine/cocaine, benzylpiperazines, buprenorphine, cannabinoids, carfentanil, dextromethorphan, fentanyl, in the drug market. furanylfentanyl, meprobamate, mescaline, methamphetamine, methadone, mitragynine, MT-45, naloxone, ocfentanyl, opioids, opiates, oxycodone, phencyclidine, phenylpiperazines, salvinorin, sufentanil, synthetic cannabinoids (JWH-018, UR-144, AB-PINACA, AB-CHMINACA), synthetic cathinones [mephedrone, methcathinone, alpha- pyrrolidinopentiophenone (alpha-PVP)], tramadol, tricyclic antidepressants, U-47700, W-19, zolpidem. Methodology Three different biochip arrays were used (DOA ULTRA,
    [Show full text]
  • (12) Patent Application Publication (10) Pub. No.: US 2005/0033522 A1 Wainer Et Al
    US 20050033522A1 (19) United States (12) Patent Application Publication (10) Pub. No.: US 2005/0033522 A1 Wainer et al. (43) Pub. Date: Feb. 10, 2005 (54) COMPUTER-BASED MODEL FOR Related U.S. Application Data IDENTIFICATION AND CHARACTERIZATION OF (63) Continuation-in-part of application No. 10/411,206, NON-COMPETITIVE INHIBITORS OF filed on Apr. 11, 2003. NCOTINIC ACETYLCHOLINE RECEPTORS AND RELATED LIGAND-GATED ON Publication Classification CHANNEL RECEPTORS (51) Int. Cl." .......................... G06F 19/00; G01N 33/48; (76) Inventors: Irving W. Wainer, Washington, DC GO1N 33/50 (US); Krzysztof Jozwiak, Abingdon, (52) U.S. Cl. ................................................................ 702/19 MD (US); Ruin Moaddel, Germantown, MD (US); Sarangan (57) ABSTRACT Ravichandran, Frederick, MD (US); A computer readable medium holding data of a molecular Jack R. Collins, Frederick, MD (US) model of a ligand-gated ion channel receptor and/or a computer System for modeling Said receptor are provided by Correspondence Address: the instant invention. The molecular model can be used to BRCH STEWART KOLASCH & BRCH design novel compounds having activity as non-competitive PO BOX 747 inhibitors of the ion channel. A preferred embodiment of the FALLS CHURCH, VA 22040-0747 (US) invention relates to nicotinic acetylcholine receptorS. Com pounds having activity as non-competitive inhibitors of (21) Appl. No.: 10/820,809 ligand-gated ion channel receptors and methods for inhib iting the receptor and treating diseases or disorderS mediated (22) Filed: Apr. 9, 2004 by function of the receptor are also disclosed. Patent Application Publication Feb. 10, 2005 Sheet 1 of 16 US 2005/0033522 A1 ONE SUBUNT OF nAChR - N NH2 UGAND-BINDING STE Soffee CROSS-SECTION OF FME ASSEMBLED SUBUNITS (2xa + 3x p) OF nAChR i: T.
    [Show full text]
  • Introduced B.,Byhansen, 16
    LB301 LB301 2021 2021 LEGISLATURE OF NEBRASKA ONE HUNDRED SEVENTH LEGISLATURE FIRST SESSION LEGISLATIVE BILL 301 Introduced by Hansen, B., 16. Read first time January 12, 2021 Committee: Judiciary 1 A BILL FOR AN ACT relating to the Uniform Controlled Substances Act; to 2 amend sections 28-401, 28-405, and 28-416, Revised Statutes 3 Cumulative Supplement, 2020; to redefine terms; to change drug 4 schedules and adopt federal drug provisions; to change a penalty 5 provision; and to repeal the original sections. 6 Be it enacted by the people of the State of Nebraska, -1- LB301 LB301 2021 2021 1 Section 1. Section 28-401, Revised Statutes Cumulative Supplement, 2 2020, is amended to read: 3 28-401 As used in the Uniform Controlled Substances Act, unless the 4 context otherwise requires: 5 (1) Administer means to directly apply a controlled substance by 6 injection, inhalation, ingestion, or any other means to the body of a 7 patient or research subject; 8 (2) Agent means an authorized person who acts on behalf of or at the 9 direction of another person but does not include a common or contract 10 carrier, public warehouse keeper, or employee of a carrier or warehouse 11 keeper; 12 (3) Administration means the Drug Enforcement Administration of the 13 United States Department of Justice; 14 (4) Controlled substance means a drug, biological, substance, or 15 immediate precursor in Schedules I through V of section 28-405. 16 Controlled substance does not include distilled spirits, wine, malt 17 beverages, tobacco, hemp, or any nonnarcotic substance if such substance 18 may, under the Federal Food, Drug, and Cosmetic Act, 21 U.S.C.
    [Show full text]