Electronic Supplementary Material (ESI) for Lab on a Chip. This Journal Is © the Royal Society of Chemistry 2020

Electronic Supplementary Material (ESI) for Lab on a Chip. This journal is © The Royal Society of Chemistry 2020

2/20/2020

Supplemental Table 1. References for Nausea Qualification Set

Drug Name Reference Nausea Incidence Reference Exposure

Carboplatin Acta Oncologica 29, 593-595 (1990) J Clin Pharmacol 28, 208-215 (1988)

Oxycodone Curr Med Res Opin 25, 765-776 (2009) Clin Ther 18, 95-105 (1996)

Pomalidomide Pomalidomide. FDA Approval Package. Pomalidomide. FDA Approval Package. Label 204026/S-000 (2013-02-08). Label 204026/S-000 (2013-02-08). Retrieved from Retrieved from https://www.pharmapendium.com/br https://www.pharmapendium.com/bro owse/fda/Pomalidomide/178f7bb33c2 wse/fda/Pomalidomide/178f7bb33c2fb fb5d512a2c79a3c6c8c48?query=consti 5d512a2c79a3c6c8c48?query=constipa pation&includeSynonyms=true tion&includeSynonyms=true Cabozantanib Ann Oncol 28, 2813-2819 (2017) J Clin Pharmacol 55, 1293-1302 (2015)

Bortezomib Bortezomib. Mosby's Drug Consult. Bortezomib. Mosby's Drug Consult. (2006). (2006). https://www.pharmapendium.com/br https://www.pharmapendium.com/bro owse/mosby/Bortezomib/Bortezomib wse/mosby/Bortezomib/Bortezomib Raltitrexed Pfizer. (2017). Product Monograph Pfizer. (2017). Product Monograph Tomudex (Raltitrexed disodium for Tomudex (Raltitrexed disodium for Injection). Retrieved from Injection). Retrieved from https://www.pfizer.ca/sites/g/files/g1 https://www.pfizer.ca/sites/g/files/g10 0050796/f/201710/TOMUDEX_PM.pdf 050796/f/201710/TOMUDEX_PM.pdf Tapentadol Curr Med Res Opin 25, 765-776 (2009) Drugs 70, 1719-1743 (2010)

Bosutinib Haematologica 103, 1298-1307 (2018) Bosutinib Monohydrate. FDA Approval Package. Label 203341/S-015 (Revised 10/2018). Retrieved from https://www.pharmapendium.com/bro wse/fda/Bosutinib%20Monohydrate/f5 513801f774cb2f3723257e3147c3e9 Ixabepilone Ixabepilone. FDA Approval Package. Ixabepilone. FDA Approval Package. Label 022065/S-006 (2011-10-20). Label 022065/S-006 (2011-10-20). Retrieved from Retrieved from https://www.pharmapendium.com/br https://www.pharmapendium.com/bro owse/fda/Ixabepilone/133ec8399fcb5 wse/fda/Ixabepilone/133ec8399fcb53c 3c2063d1aa6629ba2ec 2063d1aa6629ba2ec

1 2/20/2020

Decitabine Decitabine. Mosby's Drug Consult. Eisai. (2010). DACOGEN® (decitabine) (2006). for INJECTION: Highlights of Prescribing https://www.pharmapendium.com/br Information. Retrieved from owse/mosby/Decitabine/Decitabine https://www.accessdata.fda.gov/drugs atfda_docs/label/2010/021790s006lbl. pdf Pemetrexed Pemetrexed Disodium. Mosby's Drug Pemetrexed Disodium. FDA Approval Consult. (2006). Package. Clinical Pharmacology and https://www.pharmapendium.com/br Biopharmaceutics Review 021462/S- owse/mosby/Pemetrexed%20Disodiu 000 Part 01 (2002-10-24). Retrieved m/Pemetrexed from: https://www.pharmapendium.com/bro wse/fda/Pemetrexed%20Disodium/6eb 6e273a10c29b7aa117782946caadf Lubiprostone Lubiprostone. Mosby's Drug Consult. Lubiprostone. Mosby's Drug Consult. (2006). (2006). https://www.pharmapendium.com/br https://www.pharmapendium.com/bro owse/mosby/Lubiprostone/Lubiprosto wse/mosby/Lubiprostone/Lubiproston ne e Varenicline Varenicline Tartrate. Mosby's Drug J Clin Pharmacol 46, 1439-1448 (2006) Consult. (2006). https://www.pharmapendium.com/#/ browse/mosby/Varenicline%20Tartrat e/Varenicline Ritonavir Ritonavir. Mosby's Drug Consult. Ritonavir. Mosby's Drug Consult. (2006). (2006). https://www.pharmapendium.com/#/ https://www.pharmapendium.com/#/b browse/mosby/Ritonavir/Ritonavir rowse/mosby/Ritonavir/Ritonavir Mycophenolic Mycophenolic Acid. Mosby's Drug Mycophenolic Acid. Mosby's Drug acid Consult. (2006). Consult. (2006). https://www.pharmapendium.com/#/ https://www.pharmapendium.com/#/b browse/mosby/Mycophenolic%20Acid rowse/mosby/Mycophenolic%20Acid/ /Mycophenolic%20Acid Mycophenolic%20Acid Docetaxel See Pemetrexed Disodium. Mosby's Clin Cancer Res 10, 1976-1983 (2004) Drug Consult. (2006). https://www.pharmapendium.com/br owse/mosby/Pemetrexed%20Disodiu m/Pemetrexed Tramadol (ER) Tramadol Hydrochloride. Mosby's Tramadol Hydrochloride. Mosby's Drug Drug Consult. (2006). Consult. (2006). https://www.pharmapendium.com/#/ https://www.pharmapendium.com/#/b browse/mosby/Tramadol%20Hydrochl rowse/mosby/Tramadol%20Hydrochlor oride/Tramadol%20Hydrochloride ide/Tramadol%20Hydrochloride Duloxetine Duloxetine Hydrochloride. Mosby's Clin Pharmacokinet 50, 281-294 (2011) Drug Consult. (2006). https://www.pharmapendium.com/#/ browse/mosby/Duloxetine%20Hydroc

2 2/20/2020

hloride/Duloxetine%20Hydrochloride

Pentostatin Pentostatin. Mosby's Drug Consult. Pentostatin. FDA Approval Package (2006). 020122/S-001 Part 06 (1991-10-11). https://www.pharmapendium.com/#/ Retrieved from browse/mosby/Pentostatin/Pentostati https://www.pharmapendium.com/bro n wse/fda/Pentostatin/a3ec8fb5c6bfbde 4ca1d0b11732de5ef Dofetilide Dofetilide. Mosby's Drug Consult. Br J Clin Pharmacol 50, 247-253 (2000) (2006). https://www.pharmapendium.com/#/ browse/mosby/Dofetilide/Dofetilide Febuxostat Febuxostat. FDA Approval Package. Febuxostat. FDA Approval Package. Label 021856/S-013 (2019-02-22). Pharmacology Review 021856/S-000 Retrieved from Part 01 (2009-01-05). Retrieved from https://www.pharmapendium.com/br https://www.pharmapendium.com/bro owse/fda/Febuxostat/3dbd0fb13eb34 wse/fda/Febuxostat/f82153647be4737 28c822846570b4d0861 42615b8a6a2f24fcc Amlodipine Amlodipine Besylate. Mosby's Drug Clin Pharmacokinet 22, 22-31 (1992) Consult. (2006). https://www.pharmapendium.com/#/ browse/mosby/Amlodipine%20Besylat e/Amlodipine%20Besylate Verapamil Verapamil Hydrochloride. Mosby's Br J Clin Pharmacol 33, 623-627 (1992) Drug Consult. (2006). https://www.pharmapendium.com/#/ browse/mosby/Verapamil%20Hydroch loride/Verapamil%20Hydrochloride Maprotiline Maprotiline Hydrochloride. Mosby's Br J Clin Pharmacol 37, 383-388 (1994) Drug Consult. (2006). https://www.pharmapendium.com/#/ browse/mosby/Maprotiline%20Hydro chloride/Maprotiline%20Hydrochlorid e Fesoterodine Fesoterodine Fumarate. FDA Approval Fesoterodine Fumarate. FDA Approval Package. Label 022030/S-009 (2012- Package. Label 022030/S-009 (2012-08- 08-02). Retrieved from 02). Retrieved from https://www.pharmapendium.com/#/ https://www.pharmapendium.com/#/b browse/fda/Fesoterodine%20Fumarat rowse/fda/Fesoterodine%20Fumarate/ e/427218bb4ab95e96610527dfd099a 427218bb4ab95e96610527dfd099ad00 d00 Furosemide Am. J. Med. 111, 513-520 (2001) Clin Pharmacol Ther 14, 178-186 (1974)

3 2/20/2020

Nadolol Nadolol. Mosby's Drug Consult. Eur J Clin Pharmacol 26, 125-127 (1984) (2006). https://www.pharmapendium.com/#/ browse/mosby/Nadolol/Nadolol

Simvastatin Simvastatin. Mosby's Drug Consult. Clin Pharmacokinet 31, 348-371 (1996) (2006). https://www.pharmapendium.com/#/ browse/mosby/Simvastatin/Simvastati n Finasteride Finasteride. FDA Approval Package. Finasteride. Mosby's Drug Consult. Medical/Clinical Review 020788/S-000 (2006). Part 03 (1997-12-19). Retrieved from https://www.pharmapendium.com/#/b https://www.pharmapendium.com/#/ rowse/mosby/Finasteride/Finasteride# browse/fda/Finasteride/fa76d8e4fb48 Brand%20Name:Propecia 29402ed41ad44706e0d5?query=naus ea&includeSynonyms=true\ Haloperidol Haloperidol. FDA Approval Package Clin Pharmacokinet 34, 227-263 (1998) 017079 (1972-01-03). Retrieved from https://www.pharmapendium.com/#/ browse/fda/Haloperidol/734c22981d4 d1510f1ca6144b87fd01e?query=naus ea&includeSynonyms=true Valsartan Lancet 370, 221-229 (2007) Eur J Clin Pharmacol 52, 371-378 (1997)

Prednisone Prednisone. FDA Approval Package. J Clin Pharmacol 53, 326-333 (2013) Medical/Clinical Review 202020/S-000 Part 04 (2011-09-27). Retrieved from https://www.pharmapendium.com/br owse/fda/Prednisone/296a610bbfd14 db2eb9c8bc2970d46b0?query=constip ation&includeSynonyms=true Oxazepam Oxazepam. Mosby's Drug Consult. (2006). Oxazepam. Mosby's Drug Consult. https://www.pharmapendium.com/#/bro (2006). wse/mosby/Oxazepam/Oxazepam https://www.pharmapendium.com/#/b rowse/mosby/Oxazepam/Oxazepam

4 2/20/2020

Supplemental Table 2. References for Vomiting Qualification Set

Reference Vomiting Incidence Reference Exposure Drug Name

Carboplatin Acta Oncologica 29, 593-595 (1990) J Clin Pharmacol 28, 208-215 (1988)

Oxycodone Curr Med Res Opin 25, 765-776 Clin Ther 18, 95-105 (1996) (2009) Raltitrexed Pfizer. (2017). Product Monograph Pfizer. (2017). Product Monograph Tomudex Tomudex (Raltitrexed disodium for (Raltitrexed disodium for Injection). Injection). Retrieved from Retrieved from https://www.pfizer.ca/sites/g/files/ https://www.pfizer.ca/sites/g/files/g100507 g10050796/f/201710/TOMUDEX_P 96/f/201710/TOMUDEX_PM.pdf M.pdf Bosutinib Haematologica 103, 1298-1307 Bosutinib Monohydrate. FDA Approval (2018) Package. Label 203341/S-015 (Revised 10/2018). Retrieved from https://www.pharmapendium.com/browse/ fda/Bosutinib%20Monohydrate/f5513801f7 74cb2f3723257e3147c3e9 Bortezomib Bortezomib. Mosby's Drug Consult. Bortezomib. Mosby's Drug Consult. (2006). (2006). https://www.pharmapendium.com/browse/ https://www.pharmapendium.com/ mosby/Bortezomib/Bortezomib browse/mosby/Bortezomib/Bortezo mib Tapentadol Curr Med Res Opin 25, 765-776 Drugs 70, 1719-1743 (2010) (2009) Ixabepilone Ixabepilone. FDA Approval Package. Ixabepilone. FDA Approval Package. Label Label 022065/S-006 (2011-10-20). 022065/S-006 (2011-10-20). Retrieved from Retrieved from https://www.pharmapendium.com/browse/ https://www.pharmapendium.com/ fda/Ixabepilone/133ec8399fcb53c2063d1aa browse/fda/Ixabepilone/133ec8399 6629ba2ec fcb53c2063d1aa6629ba2ec Cinacalcet Cinacalcet Hydrochloride. Mosby's Clin Drug Investig 34, 537–544 (2014) Drug Consult. (2006). https://www.pharmapendium.com/ #/browse/mosby/Cinacalcet%20Hyd rochloride/Cinacalcet%20Hydrochlo ride

5 2/20/2020

Cabozantanib Ann Oncol 28, 2813-2819 (2017) J Clin Pharmacol 55, 1293-1302 (2015)

Decitabine Decitabine. Mosby's Drug Consult. Eisai. (2010). DACOGEN® (decitabine) for (2006). INJECTION: Highlights of Prescribing https://www.pharmapendium.com/ Information. Retrieved from browse/mosby/Decitabine/Decitabi https://www.accessdata.fda.gov/drugsatfda ne _docs/label/2010/021790s006lbl.pdf Pemetrexed Pemetrexed Disodium. Mosby's Pemetrexed Disodium. FDA Approval Drug Consult. (2006). Package. Clinical Pharmacology and https://www.pharmapendium.com/ Biopharmaceutics Review 021462/S-000 Part browse/mosby/Pemetrexed%20Dis 01 (2002-10-24). Retrieved from: odium/Pemetrexed https://www.pharmapendium.com/browse/ fda/Pemetrexed%20Disodium/6eb6e273a10 c29b7aa117782946caadf Mycophenolic Mycophenolic Acid. Mosby's Drug Mycophenolic Acid. Mosby's Drug Consult. acid Consult. (2006). (2006). https://www.pharmapendium.com/ https://www.pharmapendium.com/#/brows #/browse/mosby/Mycophenolic%20 e/mosby/Mycophenolic%20Acid/Mycophen Acid/Mycophenolic%20Acid olic%20Acid Docetaxel See Pemetrexed Disodium. Mosby's Clin Cancer Res 10, 1976-1983 (2004) Drug Consult. (2006). https://www.pharmapendium.com/ browse/mosby/Pemetrexed%20Dis odium/Pemetrexed Ritonavir Ritonavir. Mosby's Drug Consult. Ritonavir. Mosby's Drug Consult. (2006). (2006). https://www.pharmapendium.com/#/brows https://www.pharmapendium.com/ e/mosby/Ritonavir/Ritonavir #/browse/mosby/Ritonavir/Ritonavi r Varenicline Varenicline Tartrate. Mosby's Drug J Clin Pharmacol 46, 1439-1448 (2006) Consult. (2006). https://www.pharmapendium.com/ #/browse/mosby/Varenicline%20Ta rtrate/Varenicline Duloxetine Duloxetine Hydrochloride. Mosby's Clin Pharmacokinet 50, 281-294 (2011) Drug Consult. (2006). https://www.pharmapendium.com/ #/browse/mosby/Duloxetine%20Hy drochloride/Duloxetine%20Hydrochl oride Lubiprostone Lubiprostone. Mosby's Drug Lubiprostone. Mosby's Drug Consult. (2006). Consult. (2006). https://www.pharmapendium.com/ https://www.pharmapendium.com/#/brows #/browse/mosby/Lubiprostone/Lubi e/mosby/Lubiprostone/Lubiprostone

6 2/20/2020

prostone

Amlodipine Amlodipine Besylate. Mosby's Drug Clin Pharmacokinet 22, 22-31 (1992) Consult. (2006). https://www.pharmapendium.com/ #/browse/mosby/Amlodipine%20Be sylate/Amlodipine%20Besylate Furosemide Am. J. Med. 111, 513-520 (2001) Clin Pharmacol Ther 14, 178-186 (1974) Nadolol Nadolol. Mosby's Drug Consult. Eur J Clin Pharmacol 26, 125-127 (1984) (2006). https://www.pharmapendium.com/ #/browse/mosby/Nadolol/Nadolol Simvastatin Simvastatin. Mosby's Drug Consult. Clin Pharmacokinet 31, 348-371 (1996) (2006). https://www.pharmapendium.com/ #/browse/mosby/Simvastatin/Simva statin Prednisone Prednisone. FDA Approval Package. J Clin Pharmacol 53, 326-333 (2013) Medical/Clinical Review 202020/S- 000 Part 04 (2011-09-27). Retrieved from https://www.pharmapendium.com/ browse/fda/Prednisone/296a610bb fd14db2eb9c8bc2970d46b0?query= constipation&includeSynonyms=tru e Verapamil Verapamil Hydrochloride. Mosby's Br J Clin Pharmacol 33, 623-627 (1992) Drug Consult. (2006). https://www.pharmapendium.com/ #/browse/mosby/Verapamil%20Hyd rochloride/Verapamil%20Hydrochlo ride Valsartan Valsartan. Mosby's Drug Consult Eur J Clin Pharmacol 52, 371-378 (1997) (2006). https://www.pharmapendium.com/ browse/mosby/Valsartan/Valsartan

Maprotiline Maprotiline Hydrochloride. Mosby's Br J Clin Pharmacol 37, 383-388 (1994) Drug Consult. (2006). https://www.pharmapendium.com/ #/browse/mosby/Maprotiline%20H ydrochloride/Maprotiline%20Hydro chloride

7 2/20/2020

Haloperidol Haloperidol. FDA Approval Package Clin Pharmacokinet 34, 227-263 (1998) 017079 (1972-01-03). Retrieved from https://www.pharmapendium.com/ #/browse/fda/Haloperidol/734c229 81d4d1510f1ca6144b87fd01e?quer y=nausea&includeSynonyms=true Guaifenesin Guaifenesin. Mosby's Drug Consult. Clin Pharmacol Drug Dev 2, 25-32 (2013) (2006). https://www.pharmapendium.com/ browse/mosby/Guaifenesin/Guaifen esin Oxazepam Oxazepam. Mosby's Drug Consult. Oxazepam. Mosby's Drug Consult. (2006). (2006). https://www.pharmapendium.com/#/brows https://www.pharmapendium.com/ e/mosby/Oxazepam/Oxazepam #/browse/mosby/Oxazepam/Oxaze pam Dofetilide Dofetilide. Mosby's Drug Consult. Br J Clin Pharmacol 50, 247-253 (2000) (2006). https://www.pharmapendium.com/ #/browse/mosby/Dofetilide/Dofetili de Fesoterodine Fesoterodine Fumarate. FDA Fesoterodine Fumarate. FDA Approval Approval Package. Medical/Clinical Package. Label 022030/S-009 (2012-08-02). Review 022030/S-000 Part 02 (2007- Retrieved from 01-25). Retrieved from https://www.pharmapendium.com/#/brows https://www.pharmapendium.com/ e/fda/Fesoterodine%20Fumarate/427218bb browse/fda/Fesoterodine%20Fumar 4ab95e96610527dfd099ad00 ate/bcb6ed914742fb95590f3c31c1e 8622d?query=vomiting&includeSyn onyms=true Febuxostat Febuxostat. FDA Approval Package. Febuxostat. FDA Approval Package. Label 021856/S-013 (2019-02-22). Pharmacology Review 021856/S-000 Part 01 Retrieved from (2009-01-05). Retrieved from https://www.pharmapendium.com/ https://www.pharmapendium.com/browse/ browse/fda/Febuxostat/3dbd0fb13 fda/Febuxostat/f82153647be473742615b8a eb3428c822846570b4d0861 6a2f24fcc

8 2/20/2020

Supplemental Table 3. References for Constipation Qualification Set

Reference Incidence Reference Exposure Drug Name

Clomipramine Clomipramine Hydrochloride. Clomipramine Hydrochloride. Mosby's Drug Mosby's Drug Consult. (2006). Consult. (2006). https://www.pharmapendium.co https://www.pharmapendium.com/#/browse m/#/browse/mosby/Clomipramin /mosby/Clomipramine%20Hydrochloride/Clo e%20Hydrochloride/Clomipramine mipramine%20Hydrochloride %20Hydrochloride Bortezomib Bortezomib. Mosby's Drug Bortezomib. Mosby's Drug Consult. (2006). Consult. (2006). https://www.pharmapendium.com/browse/ https://www.pharmapendium.co mosby/Bortezomib/Bortezomib m/browse/mosby/Bortezomib/Bo rtezomib Pomalidomide Pomalidomide. FDA Approval Pomalidomide. FDA Approval Package. Label Package. Label 204026/S-000 204026/S-000 (2013-02-08). Retrieved from (2013-02-08). Retrieved from https://www.pharmapendium.com/browse/f https://www.pharmapendium.co da/Pomalidomide/178f7bb33c2fb5d512a2c7 m/browse/fda/Pomalidomide/178 9a3c6c8c48?query=constipation&includeSyn f7bb33c2fb5d512a2c79a3c6c8c48 onyms=true ?query=constipation&includeSyno nyms=true Decitabine Decitabine. Mosby's Drug Consult. Eisai. (2010). DACOGEN® (decitabine) for (2006). INJECTION: Highlights of Prescribing https://www.pharmapendium.co Information. Retrieved from m/browse/mosby/Decitabine/Dec https://www.accessdata.fda.gov/drugsatfda_ itabine docs/label/2010/021790s006lbl.pdf Alosetron Alosetron Hydrochloride. Mosby's Women's Health 3, 15-27 (2007) Drug Consult. (2006). https://www.pharmapendium.co m/#/browse/mosby/Alosetron%2 0Hydrochloride/Alosetron%20Hyd rochloride Cabozantanib Ann Oncol 28, 2813-2819 (2017) J Clin Pharmacol 55, 1293-1302 (2015)

Clozapine Clozapine. Mosby's Drug Consult. Clozapine. Mosby's Drug Consult. (2006). (2006). https://www.pharmapendium.com/#/browse https://www.pharmapendium.co /mosby/Clozapine/Clozapine m/#/browse/mosby/Clozapine/Cl ozapine

9 2/20/2020

Hydromorphone BMC Palliat Care 7, 17, doi: Hydromorphone Hydrochloride. Mosby's 10.1186/1472-684X-7-17 (2008) Drug Consult. (2006). https://www.pharmapendium.com/#/browse /mosby/Hydromorphone%20Hydrochloride/ Hydromorphone%20Hydrochloride Tramadol (ER) Tramadol Hydrochloride. Mosby's Tramadol Hydrochloride. Mosby's Drug Drug Consult. (2006). Consult. (2006). https://www.pharmapendium.co https://www.pharmapendium.com/#/browse m/#/browse/mosby/Tramadol%20 /mosby/Tramadol%20Hydrochloride/Tramad Hydrochloride/Tramadol%20Hydr ol%20Hydrochloride ochloride Oxycodone Curr Med Res Opin 25, 765-776 Clin Ther 18, 95-105 (1996) (2009) Odansetron Ann Oncol 7, 945-952 (1996) Pharmacotherapy 18, 288-294 (1998) Duloxetine Duloxetine Hydrochloride. Clin Pharmacokinet 50, 281-294 (2011) Mosby's Drug Consult. (2006). https://www.pharmapendium.co m/#/browse/mosby/Duloxetine% 20Hydrochloride/Duloxetine%20H ydrochloride Morphine BMC Palliat Care 7, 17, doi: Morphine Sulfate. Mosby's Drug Consult. 10.1186/1472-684X-7-17 (2008) (2006). https://www.pharmapendium.com/#/browse /mosby/Morphine%20Sulfate/Morphine%20 Sulfate Cabergoline Cabergoline. Mosby's Drug Cabergoline. Mosby's Drug Consult. (2006). Consult. (2006). https://www.pharmapendium.com/#/browse https://www.pharmapendium.co /mosby/Cabergoline/Cabergoline m/#/browse/mosby/Cabergoline/ Cabergoline Voriconazole Voriconazole. Mosby's Drug Voriconazole. Mosby's Drug Consult. (2006). Consult. (2006). https://www.pharmapendium.com/#/browse https://www.pharmapendium.co /mosby/Voriconazole/Voriconazole m/#/browse/mosby/Voriconazole /Voriconazole Amlodipine Amlodipine Besylate. Mosby's Clin Pharmacokinet 22, 22-31 (1992) Drug Consult. (2006). https://www.pharmapendium.co m/#/browse/mosby/Amlodipine% 20Besylate/Amlodipine%20Besylat e Nadolol Nadolol. Mosby's Drug Consult. Eur J Clin Pharmacol 26, 125-127 (1984) (2006). https://www.pharmapendium.co m/#/browse/mosby/Nadolol/Nad olol

10 2/20/2020

Lubiprostone Lubiprostone. Mosby's Drug Lubiprostone. Mosby's Drug Consult. (2006). Consult. (2006). https://www.pharmapendium.com/browse/ https://www.pharmapendium.co mosby/Lubiprostone/Lubiprostone m/browse/mosby/Lubiprostone/L ubiprostone Simvastatin Simvastatin. Mosby's Drug Clin Pharmacokinet 31, 348-371 (1996) Consult. (2006). https://www.pharmapendium.co m/#/browse/mosby/Simvastatin/S imvastatin Zolmitriptan Zolmitriptan. Mosby's Drug Zolmitriptan. FDA Approval Package. Clinical Consult. (2006). Pharmacology and Biopharmaceutics Review https://www.pharmapendium.co 020768 (1997-09-10). Retrieved from m/#/browse/mosby/Zolmitriptan/ https://www.pharmapendium.com/browse/f Zolmitriptan da/Zolmitriptan/08677a5ed621a2b5955031c 355a7420a Dofetilide Dofetilide. Mosby's Drug Consult. Br J Clin Pharmacol 50, 247-253 (2000) (2006). https://www.pharmapendium.co m/#/browse/mosby/Dofetilide/Do fetilide Prednisone Prednisone. FDA Approval J Clin Pharmacol 53, 326-333 (2013) Package. Medical/Clinical Review 202020/S-000 Part 04 (2011-09- 27). Retrieved from https://www.pharmapendium.co m/browse/fda/Prednisone/296a6 10bbfd14db2eb9c8bc2970d46b0? query=constipation&includeSynon yms=true Fomepizole Fomepizole. Mosby's Drug Fomepizole. Mosby's Drug Consult. (2006). Consult. (2006). https://www.pharmapendium.com/browse/ https://www.pharmapendium.co mosby/Fomepizole/Fomepizole m/browse/mosby/Fomepizole/Fo mepizole Trimethoprim Trimethoprim. Mosby's Drug Br J Clin Pharmacol 47, 255-259 (1999) Consult. (2006). https://www.pharmapendium.co m/#/browse/mosby/Trimethopri m/Trimethoprim Oxazepam Oxazepam. Mosby's Drug Consult. Oxazepam. Mosby's Drug Consult. (2006). (2006). https://www.pharmapendium.com/#/browse https://www.pharmapendium.co /mosby/Oxazepam/Oxazepam m/#/browse/mosby/Oxazepam/O xazepam Ritonavir Ritonavir. Mosby's Drug Consult. Ritonavir. Mosby's Drug Consult. (2006). (2006). https://www.pharmapendium.com/#/browse https://www.pharmapendium.com/# /mosby/Ritonavir/Ritonavir

11 2/20/2020

/browse/mosby/Ritonavir/Ritonavir

Finasteride Finasteride. FDA Approval Package. Finasteride. Mosby's Drug Consult. (2006). Medical/Clinical Review 020788/S- https://www.pharmapendium.com/#/browse 000 Part 03 (1997-12-19). Retrieved /mosby/Finasteride/Finasteride#Brand%20N from ame:Propecia https://www.pharmapendium.com/# /browse/fda/Finasteride/fa76d8e4fb4 829402ed41ad44706e0d5?query=nau sea&includeSynonyms=true