Watlow® Thermal Solutions For Medical And Clinical Applications Innovative Thermal Solutions For Medical And Clinical Applications

emperature continues to play an important role T in the development of new medical equipment, biotechnology and clinical diagnostic instrumentation. With 50 years’ experience in the Life Science industries, Watlow® is a leader in breaking new ground in designing, manufacturing and supporting innovative thermal solutions to meet medical advancements and new industry requirements. Leading medical equipment manufacturers rely on Watlow solutions for their patient care equipment, surgical devices and biotechnology and clinical diagnostic instrument application needs.

Watlow Thermal Solutions Deliver Benefits That Make The Difference: ■ Greater temperature responsiveness ■ Accurate temperature control of critical processes ■ Low leakage current compliance ■ Reduced cost, space and device weight ■ Superior temperature measurement ■ Lower heater mass and temperature uniformity ■ Faster processing times ■ Reduction in moving parts ■ Product miniaturization ■ Set up simplification Global Thermal Leadership

ith a reputation for delivering dedicated global resources will deliver W expert application knowledge, an on-time, cost-effective solution to global manufacturing capabilities, meet your requirements, wherever exceptional technical support and and whenever needed. We realize that service, Watlow is a preferred and there is no “one-size-fits-all” solution. trusted partner with leading medical You can count on the collective equipment manufacturers. As a global knowledge of Watlow’s global team We Ask The company, we support international of more than 400 consultative sales design guidelines, compliance and agents, field engineers, product Right Questions agency approvals including RoHS, specialists and system engineers W.E.E.E, CE and UL®. From routine to offer a choice of solutions that fit To Deliver The customer issues to engineering and the intended use for your particular technical problem solving, Watlow’s medical device application. Best Solution Designing the best heater solution requires technical understanding of thermal Choose The Right Partner requirements and business acumen to best service your hether it is redesigning existing cycle. Watlow has a proven track application needs. Technical W equipment to extend product record in producing high volume, questions we will address life or developing a custom assembly complex heaters and assemblies and during the conversation with a design for new equipment, we will a worldwide presence to leverage ask the right questions to solve your our vast market knowledge across device engineer include: problem quickly and correctly. borders. ■ What is the application?

■ We can complement your team at any Partner with Watlow and take Is the device heating air, gas, fluid or solid material? project stage from concept to quick advantage of our broad selection of prototyping and throughout heaters, sensors and controllers– ■ What is the process your product’s life designed to work together temperature? for optimal efficiency ■ What is the temperature ramp and long life. rate? ■ What are the dimensional requirements? ■ Are there any known material compatibility issues? ■ Are there any voltage limitations? ■ Are there any special agency approval requirements? ■ What is the heater life expectancy? ■ Where is the sensor located? ■ How is the system monitored and controlled? ■ What is the expected life cycle of the device?

Medical and Clinical Thermal Solutions - 1 Thermal Solutions For Medical Equipment And Patient Care

lectric heaters and subassemblies into the body, stabilize equipment Eenhance the operation of various performance, enhance surgical types of medical, patient care and procedures, sterilize instruments and clinical diagnostic equipment. for many other applications.

Patient safety is critical in equipment Injecting warmed fluids into a and heater design. Safety patient in post-operative recovery considerations include electrical can increase body temperature and (low leakage current), touch safe comfort while accelerating recovery. characteristics and thermal stability. Watlow’s flexible, cartridge and Medical and diagnostic devices ULTRAMIC® heaters monitor and Watlow Thermal are covered by several regulatory control thermal and other processes organizations including FDA, UL® and that are critical to ensuring patient Solutions Are CE. Watlow heaters are engineered safety and well being by keeping body and manufactured for compliance with temperature close to 37°C (98.6°F). Designed To Solve medical equipment, mechanical and electrical isolation requirements and Your Medical commonly include on-board monitors And Clinical and safety limit controllers. Watlow designs heaters and thermal Application Needs subassemblies to incubate cultures, add warm to respiratory ■ Anesthesia delivery systems equipment, heat fluids before injection ■ Blood and intravenous (IV) fluid warmers ■ Transfusion equipment ■ Syringe contrast media heating ■ Bloodless surgical procedures ■ Hemodialysis and kidney dialysis machines ■ Infant warmers and incubators ■ Insufflators ■ Lithotripters ■ Oxygen sensor electrodes ■ Respiratory therapy devices (, nebulizers and ventilators) ■ Thermal ablation instruments ■ Hypothermia (warming blankets) ■ Wound therapy systems ■ Cyrotherapeutic chambers ■ Apheresis equipment

2 - Medical and Clinical Thermal Solutions Thermal Solutions For Biotechnology Equipment And Clinical Diagnostic Instrumentation

iotechnology equipment and The need for greater throughput at Bdevices are used to extract, less cost has been met with smaller replicate, amplify and sequence devices that can turn tests quickly DNA from genes. Clinical diagnostic at a reduced cost. Meeting this instruments are used in hospitals, need drives tighter requirements clinics, commercial laboratories and for temperature accuracy and test sites to perform tests on human repeatability. Watlow’s design team blood and other body fluids. will work closely with your engineers Biotechnology to develop thermal assemblies with Watlow has developed high precision modular design concepts that reduce And Clinical heater and controller solutions for design time and costs, and provide biotechnology equipment and clinical logistics support for the final product. Diagnostic diagnostic instrument applications when a uniform operating temperature Equipment at or near a body temperature of 37°C (98.6°F) is required for That Integrate effective application performance. Some applications, including cell Watlow Thermal incubation and sterilization, may require higher temperatures. Solutions Precise temperature is a ■ Blood gas analyzers critical factor for most ■ biotechnology and Clinical chemistry analyzers clinical applications ■ Coagulation analyzers where incubation and ■ Genetic analyzers for DNA transfer of fluids is sequencing required as part of a ■ Hematology analyzers process. ■ Hybridization ovens ■ Immunoassay analyzers ■ Integrated systems analyzers ■ In-vitro diagnostics (IVD) ■ Lab-on-a-chip thermal systems ■ Magnetic resonance imaging (MRI) ■ Thermal cyclers

Medical and Clinical Thermal Solutions - 3 Ceramic Heaters

ULTRAMIC® Advanced Ceramic Heaters

Features and LTRAMIC® advanced ceramic A very low leakage current, as low as Uheaters are designed for 1μA even at standard line voltages, Benefits medical devices and clinical can eliminate the need for step-down applications where electrical safety, isolation transformers or low-voltage High dielectric strength small size, fast temperature ramp power supplies which add size, weight ■ Delivers superior electrical rates and cleanliness are critical. and cost to the system. Applications such as respiratory performance Available in a variety of miniature therapy equipment, clinical diagnostic ■ Ensures low leakage current shapes and sizes, fast responding instrumentation and DNA analysis < 10µA at 500VAC and 100°C ULTRAMIC heaters feature watt are an ideal match for ULTRAMIC’s (212°F) densities, up to 1000 W/in2 capabilities. ■ Enables high breakdown voltage (155 W/cm2) and deliver operating >2000VDC Constructed using aluminum nitride temperatures as high as 600°C (AlN), ULTRAMIC advanced ceramic (1112°F) for optimal performance and Robust aluminum nitride (AlN) heaters incorporate a proprietary equipment effectiveness. ceramic construction to provide maximum ■ Provides a clean, non- performance and long life in contaminating heat source demanding applications. The robust ■ Offers homogeneous assembly ceramic construction creates a clean, with no open porosity for non-contaminating heat source atmospheric or vacuum that is resistant to chemical applications attack and moisture ingress. High thermal conductivity and watt densities ■ Enables ultra-fast temperature ramp rate of up to 150°C (270°F) per second ■ Provides uniform temperatures across the heater’s surface ■ Allows for quick cool down Type K thermocouple integrated with assembly ■ Provides process control or high limit safety protection ■ Improves accuracy with optimized temperature sensing ■ Delivers a high response rate in Watlow ramping applications ULTRAMIC advanced gency recognition and A ceramic heaters safety compliance provide maximum performance and ® ■ UL long life when ■ CE patient safety and cleanliness are ■ RoHS application critical.

4 - Medical and Clinical Thermal Solutions Cartridge Heaters

FIREROD® Cartridge Heaters

atlow’s FIREROD® cartridge Available in both imperial and Features and W heaters are designed for metric sizes with high, medium and medical equipment including baby low watt density units, FIREROD Benefits incubators and kidney dialysis is one of the most versatile and machines and injector ports. widely-used cartridge heaters. Its Magnesium oxide insulation of Incorporating engineering robust construction and operating specific grain and purity excellence and supported characteristics help to reduce ■ Results in high dielectric by more than half a downtime and heater replacement strength and contributes to century of solid industry costs. Service life of FIREROD faster heat up performance, Watlow’s heaters has proven to be 12 Minimal sheath spacing FIREROD cartridge heater times longer than other between the element wire and is an excellent solution for cartridge heaters, sheath medical applications that require even at high ■ Prolonged heater life due to heating aluminum, stainless steel temperatures. lower internal temperature or other metal subassemblies. Built using premium materials and tight ■ Special low leakage designs manufacturing process controls, the available FIREROD cartridge heater provides Swaged construction superior and uniform ■ Delivers higher watt density up temperatures. to 400 W/in2 (62 W/cm2) ■ Enables higher temperature capacity ■ Provides maximum heat transfer efficiency ■ Increases dielectric strength Internal thermocouple option ■ Allows use in space-restricted applications 1 Special low mass /8 in. diameter available ■ Provides superior performance in a small package ■ Delivers better heat transfer ■ Enables faster response time

Sheath Agency recognition and safety compliance Pins ■ UL® MgO Insulator Nickel-Chrome ■ ® Resistance Wire UL Type LL for low leakage Seal applications Lead Wires The FIREROD cartridge heater is built to ■ CE last, providing the smallest no-heat section ■ in the industry on both ends of the heater. RoHS

No Heat Section Medical and Clinical Thermal Solutions - 5 Fluid Delivery Heaters

FREEFLEX® Heaters

lood warmers, IV fluid warmers, This innovative design enables B blood transfusion equipment, efficient, responsive heating and fluid syringe heating and contrast temperature control over a portion or media heating are all used to warm the entire length of the tube contents. fluids injected into a patient. The element is evenly wound to ensure reliable, close contact for ® Watlow’s FREEFLEX heater is ideally uniform heating where needed. suited for automated fluid delivery that requires uniform heat transfer. Its A flexible, durable jacket covers the thin, bendable properties allow it to fit wound element, allowing the tubing eatures and directly into applications that require to flex and move. The result is fluid F complex shapes and geometries. delivery to multiple locations from a Benefits FREEFLEX heaters used for fluid single supply source. For stationary delivery provide reliable, fast heat up applications, FREEFLEX heated Flexible heat-up and transport and cool down rates, uniform heat tubing is conveniently routed around system distribution and high watt densities. system components. For added

■ versatility, FREEFLEX is available with Eliminates the need for heated The FREEFLEX heating element and reservoir systems in many optional thermocouples or thermistor sensor directly contact the perimeter applications temperature sensors integrated with of the tubing to effectively transfer the thermal system. Direct contact between the energy to fluids within an inside heating element and tubing diameter. Its ability to move fluids ■ Provides efficient, highly within diameters as small as 0.8 mm responsive heating (1/32 in.) and operate up to a maximum temperature of 100°C (212°F) make Available in three this FREEFLEX heater ideal for reagent configurations transfer. ■ Flexible design allows tubing to flex, coil or bend around FREEFLEX heaters reduce power system components, enabling requirement as heat is available directly convenient retrofits where it is needed without any temperature loss. ■ Pre-formed design extends the tube length in smaller volume ■ Molded design offers a compact heating assembly for easy installation Integral sensors ■ Maintain close control of the heater and fluid temperatures Low voltage design ■ Ensures safety Miniature sizes with an inside diameter as small as 0.88 mm (1/32 in.) ■ Heats and transports fluids within tiny spaces

6 - Medical and Clinical Thermal Solutions Fluid Delivery Heaters

Syringe Heaters

atlow syringe heaters were The Watlow syringe heater is available W developed specifically to in two configuration types with an Features and match the unique needs of medical optional, repeatable temperature injection applications. Fluid and sensing controller. The silicone/wire Benefits drug delivery that maintains precise configuration accommodates varying liquid temperatures and reduces syringe size needs. The translucent, Optional, precise, repeatable fluid viscosity maximizes patient high-tech laminate construction of temperature sensing control comfort and decreases risk. Body the polycarbonate/foil design enables with a fully redundant system temperature injections are more easily fluid levels and air bubbles to be easily ■ Precise fluid temperatures introduced, particularly for patients viewed and monitored. Its smooth maximize patient comfort and in a frail or distressed condition. outer surface and radius on all inside minimize risk Used in contrast delivery system corners facilitate easy cleaning. Temperature stability yields applications for angiography and CT viscosity stability scanning, Watlow syringe heaters An overmold design houses the ■ Ensures accuracy and maintain temperature consistency and optional electronic controller and/ repeatability of test results reduce viscosity variation to increase or temperature sensor to allow diagnostic accuracy. trouble-free servicing Durable, reliable heater design and extend and construction Flexible and adaptable, Watlow’s heater life. The ■ Fits snugly to the outside syringe heaters deliver superior overmold can surface of the syringe to ensure operational performance, long life be modified precise heating and can be customized to meet most and color ■ Formed heater body holds firmly original equipment manufacturer matched for to the syringe center (OEM) requirements. a seamless, integrated ■ Reinforced power cord to meet appearance. pull strength requirements up to 89 N (20 lbF) ■ Less equipment down time minimizes the need to reschedule procedures ■ Carries a longer product life than bimetal construction Silicone/wire configuration ■ Adaptable and flexible design accommodates various syringe sizes Polycarbonate/foil configuration

■ Clear material enables easy viewing and monitoring for air bubbles ■ Customizable design meets most original equipment manufacturer requirements ■ Overmold can be modified and color matched for a seamless, integrated appearance

Medical and Clinical Thermal Solutions - 7 Flexible Heaters

Polyimide Flexible Heaters

olvent-resistant polyimide is S a thin, lightweight organic polymer film that provides excellent tensile strength, tear resistance and dimensional stability. Watlow’s polyimide heater is ideal for IV heaters, respiratory therapy units and blood, fluid and endoscope warmers. It is also used for DNA analysis equipment and clinical diagnostic instrumentation that require low in a vacuum or resistance to radiation, fungus and Features and chemicals. Watlow uses an enhanced Benefits precision registration cutting process to provide polyimide Etched foil provides high- heaters with tight tolerance tolerance physical and to fit exact application A polyimide heater is bonded to a electrical properties customer supplied plate for a renal and power needs. Precise dialysis machine. ■ Thermal stability across a wide temperature distribution and temperature range up to 200°C proper bonding or attachment (392°F) methods to subassemblies can ■ High dielectric strength: 5000 reduce installation costs. Watlow’s volts per 0.025 mm (0.001 in.) engineering team can engineer ■ Flexible: minimum bend radius a heater design and develop a of 0.8 mm (1/32 in.) production schedule that best fits your needs. ■ Material easily wipes clean Transparent polyimide materials

■ Allows internal construction to be easily inspected Agency recognition and safety compliance ■ UL® ■ C-UL® ■ Facilities easy agency approval for finished design A polyimide lead extension provides a flexible and robust power connection to the heater assembly used in DNA test equipment.

8 - Medical and Clinical Thermal Solutions Flexible Heaters

Silicone Rubber Heaters

ugged, yet thin, lightweight and Silicone rubber heaters are used R flexible, Watlow silicone rubber in medical applications for blood heaters put heat where it is needed analyzers, infant warmers, respiratory to improve heat transfer, speed therapy units, test tube heaters, warm-ups and decrease wattage continuous and variable positive requirements. Fiberglass-reinforced airway pressure (CPAP and VPAP) silicone rubber provides dimensional machines, and can be formed to stability without sacrificing flexibility. A fit many custom designed device Features and minimal amount of material separates components. They can be supplied the element from the part to enable as a complete thermal assembly to Benefits rapid and efficient heat transfer. reduce installation costs. With vast Designed to fit exact shape global resource capabilities, Watlow and size requirements can accommodate a few quick- ■ turn prototypes and ramp up to a Conforms to equipment configuration for precise power production volume of thousands of where needed. heaters per year. ■ Power density can be easily distributed to provide superior Watlow silicone rubber temperature distribution heaters can be designed to ■ Available in many design fit the exact configurations to accommodate shape and most geometries size for specific Moisture, abrasion and applications. chemical- resistant silicone rubber material ■ Extends heater longevity Many combinations of element and silicone rubber constructions are available ■ Heater design can best match application needs Vulcanized adhesives or fasteners

■ Sets up easily and provides strong bonding between the heater and the part Process temperature range ■ Up to 220°C (428°F) Agency recognition and safety compliance ■ UL®, C-UL® ■ VDE, CE ■ Facilitates easy agency approvals of finished equipment

Medical and Clinical Thermal Solutions - 9 Tubular Heaters

WATROD™ and FIREBAR® Tubular Heaters

atlow’s round WATROD™ and With more than 30 years’ experience, W flat FIREBAR® tubular heating Watlow can design the optimum elements are used in both radiant and incubator solution to match your modes to provide uniform application needs. temperature profiles. They are ideal for use in demanding applications, such Tubular elements and assemblies are as those used in baby incubators, also used in sterilizers and in medical which require uniform temperature as applications to heat liquids in non- well as minimal surface material loss invasive surgical equipment. while reducing leakage to ground. Features and Benefits Precision bending with intricate geometrical formations ■ Enables the heating element to be designed around available space to maximize efficiency ■ Provides reliable heater life internal thermocouple temperature sensor ■ Reduces assembly costs and is more responsive and accurate compared to separate surface mount thermocouple temperature sensors High temperature, moisture- resistant seals The high-temperature tubular heater’s Inconel® 600 sheath material ■ Protect against moisture and special internal construction deliver high contamination and are UL® rated temperature performance. up to 371°C (700°F) ■ Minimize low leakage current at high temperatures Wire to Pin 360˚ Magnesium oxide (MgO) Fusion Weld Metal Sheath insulation filled sheath Threaded ■ Provides good dielectric Stud strength and heat transfer Agency recognition and safety compliance ■ UL® ■ CSA® Nickel-Chromium Resistance Wire Terminal Pin MgO Insulation Tubular heater construction 10 - Medical and Clinical Thermal Solutions Temperature and Process Controllers

SERIES EHG® SL10 Process Features and Controller And Safety Limit Benefits Process controller and ® The EHG SL10 in-line or sub-panel he Watlow SERIES EHG SL10 safety limit in one package T process controller and safety limit mount temperature controller/limit ■ ® is a powerful system that integrates is an ideal combination for thermal Meets UL 1998 and CE 60730 requirements a heater with an adjustable set management of medical applications point temperature controller, high/ including patient warming, fluid ■ Easy to install, compact design low temperature alert, a power warming or any medical device ■ Ethernet compatible, ISO-9001 switching device and a high requiring thermal management. compliant and meets all UL®, temperature safety Its small size, adjustable CSA, CE and VDE certifications or fixed set point, limit. Optional display/ precise temperature communications module control with a built in agency ■ Enables an easy upgrade with the approved base device controller/ ■ Offers a low cost field upgrade safety limit ■ Provides easy, snap-on enables installation versatility Accurate and flexible across many temperature process applications. controller

■ Replaces problematic bi-metal with accurate electronic temperature process controllers ■ Permits process parameters to be easily changed Integrated high/low temperature alert signal relay

■ Provides a dry contact, mechanical output to activate external alarm or process function ■ Signals control status with three integrated LEDs The EHG ■ Allows a signal of up to SL10 process controller’s 2 amperes, 30VAC/VDC, Form A optional display/ to alert if the process temperature communication is out of range limits module provides easy snap on Health check diagnostics installation with the flexible heater. ■ Monitors the maximum heater process temperature, maximum ambient temperature and thermocouple operation ■ Provides a health check signal to inform the operator that the process is working correctly

Medical and Clinical Thermal Solutions - 11 Temperature and Process Controllers

EZ-ZONE® Integrated Multi-Function Controller

atlow’s family of EZ-ZONE® The EZ-ZONE RM controller saves W integrated multi-function time, cost and space for a variety of controllers combine temperature, applications. It allows multiple inputs process and machine control, to be mixed and matched to configure over- and under-temperature limit up to 152 PID loops and monitor up protection, high amperage power to 256 analog inputs. The EZ-ZONE switching, safety disconnects and RM controller is perfect for complex field communications into a single applications that require multiple Features and package. Offering a variety of modular sensing points and built-in logic. form factors and display types in place Benefits of several components, the EZ-ZONE The highly scalable EZ-ZONE PM is convenient and reliable. panel mount controller reduces EZ-ZONE RM AND system complexity and the cost of EZ-ZONE PM CONTROLLER Watlow multi-function controllers are thermal loop ownership. It can be ideal for use in simple to complex ordered as a PID controller, as an Special output function over/under limit controller or all of algorithm for peltier devices medical applications, such as DNA processing and blood or these functions can be ■ Assures that the action of the combined into the bi-directional control does not glucose monitoring. When damage the peltier device data logging, data storage integrated controller. and communications are Communicates with an operator interface terminal critical, multi-function (touch screen) controllers provide ■ Transmits multiple messages in primary and secondary various languages to medical temperature control with personnel universal inputs, including Combines temperature thermistors. EZ-ZONE control and agency approved temperature controllers can factory mutual (FM) limit in a be configured with an agency- single package approved microprocessor ■ Eliminates need for two temperature controller and discrete and independent limit in one package. Simple controllers which reduces cost applications requiring one loop of and space requirements control and one limit loop can be The EZ-ZONE Combine or order optional achieved in as small as a 1/16 DIN RM controller integrated controller package size. saves time, cost functions and space for a variety of applications. ■ Saves engineering time and labor costs while shortening project schedules Enables thermistor input ■ Accuracy to display precise temperature readings Current monitoring ■ Detects heater current flow The EZ-ZONE PM and provides alarm indication controller displays accurate and precise of output device or heater load temperature readings. failure 12 - Medical and Clinical Thermal Solutions Sensors

Temperature Sensor Technologies

chieving temperature sensor Watlow’s technological expertise in A accuracy, repeatability and microprocessor technology, combined stability are key factors that determine with multiple input/output applications how well an application performs. For (I/O), includes resistance temperature some applications, such as measuring detectors (RTDs), thermocouple blood or body fluid temperatures, and thermistor input for precise response to small changes in temperature measurement. temperature is critical to patient health. Watlow’s thermistor, RTDs and eatures and thermocouple sensor assemblies F Watlow thermal engineers combine can be used in autoclaves and for Benefits deep knowledge of various fluid, air or surface measurement and applications with material science, monitoring applications. Thermistors Designed to maintain , electrical properties are highly sensitive to small changes accuracy over the life of and connectivity to develop sensors in temperature and maintain accurate the sensor for specific medical applications. The temperatures over a limited range. ■ Permits dependable, accurate result is a sensor that consistently RTDs are very accurate and linear readings to improve process yields the best performance in over a wide operating range. control and application medical device applications. Thermocouples can be produced in performance very small diameter packages with a Typically integrated with a Watlow flexible metal sheath. Interchangeable sensor heater for clinical diagnostic probes applications, Watlow sensor ■ Allow probes from different assemblies deliver fast, accurate lots to be substituted without and repeatable temperature recalibrating to provide measurement. consistent control of critical processes Small size and low mass

■ Enables fast response to small temperature changes ensuring application accuracy

Watlow manufactures a wide Sensor assembly integration variety of sensors to match with Watlow heaters and medical application needs. controllers

■ Provides single-source access to expert design, products and engineering services for Thermocouples RTDs Thermistors all of your thermal system V R R 2-wire components – heaters, temperature sensors and power controllers Voltage Resistance Resistance T T T Temperature Temperature Temperature Watlow offers an array of precision sensor products Medical and Clinical Thermal Solutions - 13 Case Histories

Watlow FIREROD Cartridge Heater Ensures Temperature Stability For Kidney (Renal) Dialysis Machine

Problem Application Solution Kidney dialysis machines purify the To ensure temperature stability Watlow’s engineering team blood in patients whose kidneys and meet safety requirements, collaborated with a medical equipment have failed. During the kidney dialysis the application requires an in-line manufacturer to develop a heater procedure, it is critical that body immersion heater that will not touch solution to meet all temperature and temperature is regulated to prevent the perimeter of the plastic water medical device requirements. A 3 mm the occurrence of thermal shock. A transport tube. If the plastic tubing (1/8 in.) thick flange is attached to a kidney dialysis machine implements were to make contact with the heater, 16 mm (0.625 in.) diameter by 18 cm a three-step thermal process that the tube would melt. Also, for the (7 in.) long FIREROD heater. The typically includes a 90°C (194°F) patient’s safety, medical products flange allows the FIREROD to remain disinfection cycle, followed by a 37°C require a low leakage current. To concentric with the plastic tube. To (98.6°F) cycle to clean the blood and a comply with UL® safety requirement meet leakage specifications, a 90°C (194°F) system cleaning 60601-1, a Class 1 medical Type LL, special low leakage FIREROD cycle at the end of device must have a heater capable of maintaining leakage usage each day. leakage current below 15 µA is used. of less than 300µA.

While maintaining fluids at exactly 37°C (98.6°F), the special low leakage FIREROD heater meets stringent UL® medical device safety requirements.

14 - Medical and Clinical Thermal Solutions Case Histories

Watlow’s Syringe Heater Increases Temperature Consistency

Problem Application Solution An accurate heater was needed To detect blockages, a fluid is injected The application required a robust, for an injection system to view soft into the patient’s veins. This fluid is compact and reusable heater package tissue in patients for a company that designed to be opaque to X-ray or CT to ensure accurate temperature makes angiography and CT scanning scanning devices. Due to the contrast control for the injection system and equipment used by hospitals and in the X-ray image, a technician can provide the capability to view the laboratories. At 16°C (60°F), contrast easily view the areas where the fluid opaque contrast media used in X-ray media has a high viscosity which is has filled the normal vein and the area and CT tests. Watlow designed a reduced by approximately 50 percent that the fluid is blocked from entering. syringe heater to fit snugly to the at 37°C (98.6°F). Temperature stability This contrast media fluid is very thick outside surface of the syringe. A is critical to delivering consistent test in consistency (or of a high viscosity) molded pod on the backside of the results. An angiogram can be used to and the consistency changes housing integrates a sensor and determine if there are blockages in the considerably with temperature. The a custom temperature and limit veins around a patient’s material will change to be one-half controller. Prior to performing the heart. of the 16°C (60ºF) viscosity procedure, the syringe is placed at the 37°C (98ºF) on top of the injector head, and viscosity. Temperature the syringe heater is clipped to the stability is critical syringe to heat the fluid to the required to delivering temperature. The heater consistently consistent test maintains the injection medium at the results. correct temperature.

Watlow’s syringe heater, attached to the outside syringe surface, heats fluid for ultimate patient comfort and safety.

Medical and Clinical Thermal Solutions - 15 Case Histories

ULTRAMIC Advanced Ceramic Heater And EZ-ZONE® RM Controller Improve Speed Of Cancer Screening

Problem Application Solution Developing innovative technology An IHC machine required a low profile Watlow’s ULTRAMIC advanced solutions that enhance diagnostic heater with a non-contaminating ceramic heater and EZ-ZONE® RM capabilities of anatomic pathology construction, fast temperature ramp controller are used with the IHC laboratories provides clinicians with rate and quick recovery time to enable machine to radiantly heat biopsy rapid, reliable, actionable diagnostic the machine to generate lab results in tissue and reagents sandwiched information and advanced patient one hour. between glass slides. Using finite care. element analysis (FEA), a customized resistor circuit pattern was developed An immunohistochemistry (IHC) to optimize temperature uniformity machine, used to diagnose across the sample. The heater’s cells from cancer biopsy integrated thermocouple screenings, typically works with the EZ-ZONE RM requires several days controller to accurately for results when control the surface traditional lab temperature and prevent equipment is used. an overtemperature The customer condition. required a solution that would enable their IHC machine to analyze cells from cancer biopsy screenings in one hour. Receiving lab results while the patient is still in surgery enables the doctor to decide almost immediately if additional biopsies are required, eliminating the need for an additional surgery and associated costs. There is also a great This ULTRAMIC heater assembly and EZ-ZONE RM controller enables relief for the patient to get results as cancer screening results to be soon as possible. available in 1-2 hours.

16 - Medical and Clinical Thermal Solutions Case Histories

Silicone Rubber Heater for Blood Coagulation Analyzers

Problem Solution Detecting and timing blood clotting A turnkey assembly was is necessary for identifying diseases designed using two silicone such as hemophilia and for patients rubber heaters per heating block receiving anticoagulant drugs and to heat reagents and incubate pre-surgical examinations. Reagents the blood plasma. The silicone used in tests and blood plasma rubber heaters were factory need warming and their temperature vulcanized to the furnished part controlled to permit rapid and to achieve efficient heat transfer accurate processing. and lower customer installation costs. To allow line voltage Application operation, both heaters were wired in series. A blood clot sensing and recording By die cutting the instrument application required a high heaters, the cost of resistance heater to efficiently heat repeatedly meeting reagents for blood plasma incubation. close tolerances of the The design required a thermal solution contoured shape was to reduce complexity of the equipment reduced. while providing uniform temperature distribution.

Watlow’s flexible silicone rubber heaters apply heat directly where it is needed to improve heat transfer, speed warm ups and decrease wattage requirements. Medical and Clinical Thermal Solutions - 17 Find out more about Watlow and how we can provide thermal solutions for your company: Phone: 1-800-WATLOW2 (1-800-928-5692) E-mail: [email protected] Web site: www.watlow.com

Watlow Products and Technical About Watlow Support Delivered Worldwide Watlow designs and manufactures industrial heaters, temperature sensors, controllers and system assemblies – North American Technical Support & all of the components of a thermal system. Designing and Sales Offices manufacturing the complete thermal system allows Watlow North America 1-800-WATLOW2 to recommend, develop and deliver the optimum thermal (1-800-928-5692) solution for our customers’ equipment and process heat Asian Technical Support & Sales Offices requirements. Australia +61 3 9335 6449 China +86 21 3532 8532 Watlow manufactures thermal systems for a broad range India +91 40 6661 2700 of industries including: semiconductor processing, Japan +81 3 3518 6630 photovoltaics, energy processing, diesel emissions, Korea +82 2 2628 5770 foodservice equipment, medical equipment and aerospace. Malaysia +60 3 8076 8745 Watlow customers receive the highest level of technical engineering combined with exceptional customer service. Singapore +65 6773 9488 Taiwan +886 7 288 5168 Since 1922, Watlow has grown in product capability, European Technical Support & Sales Offices market experience and global reach. We hold more than France +33 (0) 1 41 32 79 70 200 patents and employ 2,000 employees working in Germany +49 (0) 72 53 / 94 00-0 12 manufacturing facilities in the United States, Mexico, Italy +39 024588841 Europe and Asia. We also have sales offices in 15 Spain +34 91 675 12 92 countries around the world. Our company has grown at an United Kingdom +44 (0) 115 964 0777 exponential rate, but our commitment remains the same Latin American Technical Support & – to provide our customers with superior products and Sales Office services for their individual needs. Mexico +52 442 217 6235

Watlow Trademarks Trademarks The following are registered UL®, C-UL® and cUR® are trademarks of Watlow Electric registered trademarks of Your Authorized Watlow Distributor is: Manufacturing Company: Underwriter’s Laboratories, Inc. Watlow® CSA® is a registered trademark of ULTRAMIC® CSA International WATROD™ Incoloy® and Inconel® are registered FIREBAR® trademarks of Special Metals FIREROD® Corporation. FREEFLEX® SERIES EHG® EZ-ZONE® WATROD™ is a trademark of Watlow Electric Manufacturing Company

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