Glossary of Medical Examination Terms
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Geriatric Medicine and Why We Need Geriatricians! by Juergen H
Geriatric Medicine and why we need Geriatricians! by Juergen H. A. Bludau, MD hat is geriatric medicine? Why is there a need for 1. Heterogeneity: As people age, they become more Wthis specialty? How does it differ from general heterogeneous, meaning that they become more and more internal medicine? What do geriatricians do differently when different, sometimes strikingly so, with respect to their they evaluate and treat an older adult? These are common health and medical needs. Imagine for a moment a group questions among patients and physicians alike. Many of 10 men and women, all 40 years old. It is probably safe internists and family practitioners argue, not unjustifiably, to say that most, if not all, have no chronic diseases, do not that they have experience in treating and caring for older see their physicians on a regular basis, and take no long- patients, especially since older adults make up almost half of term prescription medications. From a medical point of all doctors visits. So do we really need another type of view, this means that they are all very similar. Compare this physician to care for older adults? It is true that geriatricians to a group of 10 patients who are 80 years old. Most likely, may not necessarily treat older patients differently per se. But you will find an amazingly fit and active gentleman who there is a very large and important difference in that the focus may not be taking any prescription medications. On the of the treatment is different. In order to appreciate how other end of the spectrum, you may find a frail, memory- significant this is, we need to look at what makes an older impaired, and wheelchair-bound woman who lives in a adult different from a younger patient. -
A Crisis in Health Care: a Call to Action on Physician Burnout
A CRISIS IN HEALTH CARE: A CALL TO ACTION ON PHYSICIAN BURNOUT Partnership with the Massachusetts Medical Society, Massachusetts Health and Hospital Association, Harvard T.H. Chan School of Public Health, and Harvard Global Health Institute A Crisis in Health Care: A Call to Action on Physician Burnout Authors About the Massachusetts Medical Society Ashish K. Jha, MD, MPH The Massachusetts Medical Society (MMS) is the state- Director, Harvard Global Health Institute wide professional association for physicians and medical stu- Senior Associate Dean for Research Translation and dents, supporting 25,000 members. The MMS is dedicated Global Strategy to educating and advocating for the physicians and patients K.T. Li Professor, Dept. of Health Policy and Management, of Massachusetts both locally and nationally. As a voice of Harvard T.H. Chan School of Public Health leadership in health care, the MMS provides physician and Professor of Medicine, Harvard Medical School patient perspectives to influence health-related legislation Andrew R. Iliff, MA, JD at both state and federal levels, works in support of public Lead Writer and Program Manager, Harvard Global health, provides expert advice on physician practice manage- Health Institute ment, and addresses issues of physician well-being. Alain A. Chaoui, MD, FAAFP About the Massachusetts Health and President, Massachusetts Medical Society Hospital Association Steven Defossez, MD, EMHL The Massachusetts Health and Hospital Association Vice President, Clinical Integration, Massachusetts Health (MHA) was founded in 1936, and its members include and Hospital Association 71 licensed member hospitals, many of which are organized Maryanne C. Bombaugh, MD, MSc, MBA within 29 member health systems, as well as interested indi- President-Elect, Massachusetts Medical Society viduals and other healthcare stakeholders. -
Acute Liver Failure J G O’Grady
148 Postgrad Med J: first published as 10.1136/pgmj.2004.026005 on 4 March 2005. Downloaded from REVIEW Acute liver failure J G O’Grady ............................................................................................................................... Postgrad Med J 2005;81:148–154. doi: 10.1136/pgmj.2004.026005 Acute liver failure is a complex multisystemic illness that account for most cases, but a significant number of patients have no definable cause and are evolves quickly after a catastrophic insult to the liver classified as seronegative or of being of indeter- leading to the development of encephalopathy. The minate aetiology. Paracetamol is the commonest underlying aetiology and the pace of progression strongly cause in the UK and USA.2 Idiosyncratic reac- tions comprise another important group. influence the clinical course. The commonest causes are paracetamol, idiosyncratic drug reactions, hepatitis B, and Viral seronegative hepatitis. The optimal care is multidisciplinary ALF is an uncommon complication of viral and up to half of the cases receive liver transplants, with hepatitis, occurring in 0.2%–4% of cases depend- ing on the underlying aetiology.3 The risk is survival rates around 75%–90%. Artificial liver support lowest with hepatitis A, but it increases with the devices remain unproven in efficacy in acute liver failure. age at time of exposure. Hepatitis B can be associated with ALF through a number of ........................................................................... scenarios (table 2). The commonest are de novo infection and spontaneous surges in viral repli- cation, while the incidence of the delta virus cute liver failure (ALF) is a complex infection seems to be decreasing rapidly. multisystemic illness that evolves after a Vaccination should reduce the incidence of Acatastrophic insult to the liver manifesting hepatitis A and B, while antiviral drugs should in the development of a coagulopathy and ameliorate replication of hepatitis B. -
Guidelines for Developing a Team Physician Services Agreement in the Secondary School
Guidelines for Developing a Team Physician Services Agreement in the Secondary School The following document has been developed by the NATA Secondary School Athletic Trainers’ Committee in an effort to assist secondary school athletic trainers in strengthening and formalizing the relationship with a team physician. The included components for such an agreement have been suggested by the American College of Sports Medicine (ACSM) and NATA (see resources). Guidelines for Developing a Team Physician Agreement in the Secondary School is intended to serve as an overview of those key components as they apply to the secondary school setting. It should be noted that while all components cited have merit, not all may be practical for all situations. Variability with state and local regulations must also be considered. DEVELOPED BY THE SECONDARY SCHOOL ATHLETIC TRAINERS’ COMMITTEE: Larry Cooper, MS, ATC, LAT, Chair Kembra Mathis, MEd, ATC, LAT Bart Peterson, MSS, ATC, Incoming Chair Lisa Walker, ATC Denise Alosa, MS, ATC Stacey Ritter, MS, ATC Casey Christy, ATC Chris Snoddy, ATC, LAT George Wham, EdD, ATC, SCAT Chris Dean, ATC Dale Grooms, ATC Cari Wood, ATC, NATA BOD Liaison Dan Newman, MS, ATC, LAT Amanda Muscatell, NATA Staff Liaison A SPECIAL THANKS TO TEAM PHSYICIAN SERVICES AGREEMENT SUBCOMMITTEE: George Wham, EdD, ATC, SCAT Dale Grooms, ATC Casey Christy, ATC Larry Cooper, MS, ATC, LAT, Chair Bart Peterson, MSS, ATC, Incoming Chair NATA Secondary School Athletic Trainers’ Committee 2016 Disclaimer: The materials and information provided in the National Athletic Trainers’ Association (“NATA”) “Guidelines for Developing a Team Physician Services Agreement in the Secondary School” (the “Guideline”) are educational in nature, and the Guideline is published as a resource for NATA members and is intended solely for personal use/reference in the manner described herein. -
Differential Metabolism of Alprazolam by Liver and Brain Cytochrome (P4503A) to Pharmacologically Active Metabolite
The Pharmacogenomics Journal (2002) 2, 243–258 2002 Nature Publishing Group All rights reserved 1470-269X/02 $25.00 www.nature.com/tpj ORIGINAL ARTICLE Differential metabolism of alprazolam by liver and brain cytochrome (P4503A) to pharmacologically active metabolite HV Pai1,2* ABSTRACT SC Upadhya1,2* Cytochrome P450 (P450) is a superfamily of enzymes which mediates metab- 1 olism of xenobiotics including drugs. Alprazolam, an anti-anxiety agent, is SJ Chinta * metabolized in rat and human liver by P4503A1 and P4503A4 respectively, SN Hegde1 to 4-hydroxy alprazolam (4-OHALP, pharmacologically less active) and ␣- V Ravindranath1,2 hydroxy alprazolam (␣-OHALP, pharmacologically more active). We exam- ined P450 mediated metabolism of alprazolam by rat and human brain 1Department of Neurochemistry, National microsomes and observed that the relative amount of ␣-OHALP formed in Institute of Mental Health & Neurosciences, brain was higher than liver. This biotransformation was mediated by a P450 Bangalore, India; 2National Brain Research Centre, ICGEB Campus, Aruna Asaf Ali Marg, isoform belonging to P4503A subfamily, which is constitutively expressed in New Delhi , India neuronal cells in rat and human brain. The formation of larger amounts of ␣-OHALP in neurons points to local modulation of pharmacological activity Correspondence: in brain, at the site of action of the anti-anxiety drug. Since hydroxy metab- V Ravindranath, National Brain Research olites of alprazolam are hydrophilic and not easily cleared through blood- Centre, ICGEB Campus, Aruna Asaf Ali ␣ Marg, New Delhi - 110 067, India CSF barrier, -OHALP would potentially have a longer half-life in brain. Tel: +91 124 630 8317 The Pharmacogenomics Journal (2002) 2, 243–258. -
Fact Sheet - Symptoms of Pancreatic Cancer
Fact Sheet - Symptoms of Pancreatic Cancer Diagnosis Pancreatic cancer is often difficult to diagnose, because the pancreas lies deep in the abdomen, behind the stomach, so tumors are not felt during a physical exam. Pancreatic cancer is often called the “silent” cancer because the tumor can grow for many years before it causes pressure, pain, or other signs of illness. When symptoms do appear, they can vary depending on the size of the tumor and where it is located on the pancreas. For these reasons, the symptoms of pancreatic cancer are seldom recognized until the cancer has progressed to an advanced stage and often spread to other areas of the body. General Symptoms Pain The first symptom of pancreatic cancer is often pain, because the tumors invade nerve clusters. Pain can be felt in the stomach area and/or in the back. The pain is generally worse after eating and when lying down, and is sometimes relieved by bending forward. Pain is more common in cancers of the body and tail of the pancreas. The abdomen may also be generally tender or painful if the liver, pancreas or gall bladder are inflamed or enlarged. It is important to keep in mind that there are many other causes of abdominal and back pain! Jaundice More than half of pancreatic cancer sufferers have jaundice, a yellowing of the skin and whites of the eyes. Jaundice is caused by a build-up bilirubin, a substance which is made in the liver and a component of bile. Bilirubin contains a lot of yellow pigment, and gives bile it’s color. -
Hepatitis B? HEPATITIS B Hepatitis B Is a Contagious Liver Disease That Results from Infection with the Hepatitis B Virus
What is Hepatitis B? HEPATITIS B Hepatitis B is a contagious liver disease that results from infection with the Hepatitis B virus. When first infected, a person can develop Are you at risk? an “acute” infection, which can range in severity from a very mild illness with few or no symptoms to a serious condition requiring hospitalization. Acute Hepatitis B refers to the first 6 months after someone is exposed to the Hepatitis B virus. Some people are able to fight the infection and clear the virus. For others, the infection remains and leads to a “chronic,” or lifelong, illness. Chronic Hepatitis B refers to the illness that occurs when the Hepatitis B virus remains in a person’s body. Over time, the infection can cause serious health problems. How is Hepatitis B spread? Hepatitis B is usually spread when blood, semen, or other body fluids from a person infected with the Hepatitis B virus enter the body of someone who is not infected. This can happen through having sex with an infected partner; sharing needles, syringes, or other injection drug equipment; or from direct contact with the blood or open sores of an infected person. Hepatitis B can also be passed from an infected mother to her baby at birth. Who should be tested for Hepatitis B? Approximately 1.2 million people in the United States and 350 million people worldwide have Hepatitis B. Testing for Hepatitis B is recommended for certain groups of people, including: Most are unaware of their infection. ■ People born in Asia, Africa, and other regions with moderate or high rates Is Hepatitis B common? of Hepatitis B (see map) Yes. -
Hepatitis A, B, and C: Learn the Differences
Hepatitis A, B, and C: Learn the Differences Hepatitis A Hepatitis B Hepatitis C caused by the hepatitis A virus (HAV) caused by the hepatitis B virus (HBV) caused by the hepatitis C virus (HCV) HAV is found in the feces (poop) of people with hepa- HBV is found in blood and certain body fluids. The virus is spread HCV is found in blood and certain body fluids. The titis A and is usually spread by close personal contact when blood or body fluid from an infected person enters the body virus is spread when blood or body fluid from an HCV- (including sex or living in the same household). It of a person who is not immune. HBV is spread through having infected person enters another person’s body. HCV can also be spread by eating food or drinking water unprotected sex with an infected person, sharing needles or is spread through sharing needles or “works” when contaminated with HAV. “works” when shooting drugs, exposure to needlesticks or sharps shooting drugs, through exposure to needlesticks on the job, or from an infected mother to her baby during birth. or sharps on the job, or sometimes from an infected How is it spread? Exposure to infected blood in ANY situation can be a risk for mother to her baby during birth. It is possible to trans- transmission. mit HCV during sex, but it is not common. • People who wish to be protected from HAV infection • All infants, children, and teens ages 0 through 18 years There is no vaccine to prevent HCV. -
White and Brown Bagging Emerging Practices, Emerging Regulation
White and Brown Bagging Emerging Practices, Emerging Regulation Prepared By The National Association of Boards of Pharmacy White and Brown Bagging Emerging Practices, Emerging Regulation Published April 2018 Copyright 2018 National Association of Boards of Pharmacy 1600 Feehanville Drive Mount Prospect, IL 60056 USA 847/391‐4406 www.nabp.pharmacy Carmen A. Catizone, MS, RPh, DPh Executive Director/Secretary NABP Mission Statement NABP is the independent, international, and impartial Association that assists its member boards and jurisdictions for the purpose of protecting the public health. NABP Vision Statement Innovating and collaborating today for a safer public health tomorrow. ________________________________________________________________________ © 2018 by the National Association of Boards of Pharmacy. All rights reserved. No part of this publication may be reproduced in any manner without the written permission of the executive director/secretary of the National Association of Boards of Pharmacy. The terms “National Association of Boards of Pharmacy,” and “NABP,” are registered trademarks of the National Association of Boards of Pharmacy. Violation of the copyright will lead to prosecution under federal copyright laws. Table of Contents Overview……………………………………………………………………………………………………………………………..2 Results ………………………………………………………………………………………………………………………………..2 Results Background …………………………………………………………………………………………………………….3 Recommendations ………………………………………………………………………………………………………………5 References ………………………………………………………………………………………………………………………….6 -
Practitioner Acronym Table
Practitioner Acronym Table AAP American Academy of Pediatrics ABAI American Board of Allergy and Immunology ABFP American Board of Family Practitioners ABO American Board of Otolaryngology ABPN American Board of Psychiatry and Neurology AK Acupuncturist (Pennsylvania) AOBFP American Osteopathic Board of Family Physicians American Osteopathic Board of Special Proficiency in Osteopathic Manipulative AOBSPOMM Medicine AP Acupuncture Physician ASG Affiliated Study Group BHMS Bachelor of Homeopathic Medicine and Surgery BSN Bachelor of Science, Nursing BVScAH Bachelor of Veterinary Science and Animal Husbandry CA Certified Acupuncturist CAAPM Clinical Associate of the American Academy of Pain Management CAC Certified Animal Chiropractor CCH Certified in Classical Homeopathy CCSP Certified Chiropractic Sports Physician CRNP Certified Registered Nurse Practitioner CRRN Certified Rehabilitation Registered Nurse CSPOMM Certified Specialty of Proficiency in Osteopathic Manipulation Medicine CVA Certified Veterinary Acupuncturist DAAPM Diplomate of American Academy of Pain Management DABFP Diplomate of the American Board of Family Practice DABIM Diplomate of the American Board of Internal Medicine DAc Diplomate in Acupuncture DAc (RI) Doctor of Acupuncture, Rhode Island DAc (WV) Doctor of Acupuncture, West Virginia DACBN Diplomate of American Chiropractic Board of Nutrition DACVD Diplomate of the American College of Veterinary Dermatology DC Doctor of Chiropractic DDS Doctor of Dentistry DHANP Diplomate of the Homeopathic Academy of Naturopathic -
Team Physician Consensus Statement
Team Physician Consensus Statement SUMMARY QUALIFICATIONS OF A TEAM PHYSICIAN The objective of the Team Physician Consensus Statement is to provide The primary concern of the team physician is to provide physicians, school administrators, team owners, the general public, and the best medical care for athletes at all levels of participa- individuals who are responsible for making decisions regarding the medical tion. To this end, the following qualifications are necessary care of athletes and teams with guidelines for choosing a qualified team physician and an outline of the duties expected of a team physician. for all team physicians: Ultimately, by educating decision makers about the need for a qualified • Have an M.D. or D.O. in good standing, with an team physician, the goal is to ensure that athletes and teams are provided unrestricted license to practice medicine the very best medical care. • The Consensus Statement was developed by the collaboration of six Possess a fundamental knowledge of emergency care major professional associations concerned about clinical sports medicine regarding sporting events issues: American Academy of Family Physicians, American Academy of • Be trained in CPR Orthopaedic Surgeons, American College of Sports Medicine, American • Have a working knowledge of trauma, musculoskeletal Medical Society for Sports Medicine, American Orthopaedic Society for injuries, and medical conditions affecting the athlete Sports Medicine, and the American Osteopathic Academy of Sports Med- icine. These organizations have committed to forming an ongoing project- In addition, it is desirable for team physicians to have based alliance to “bring together sports medicine organizations to best clinical training/experience and administrative skills in serve active people and athletes.” some or all of the following: • Specialty Board certification EXPERT PANEL • Continuing medical education in sports medicine • Formal training in sports medicine (fellowship train- Stanley A. -
How Is Alcohol Metabolized by the Body?
Overview: How Is Alcohol Metabolized by the Body? Samir Zakhari, Ph.D. Alcohol is eliminated from the body by various metabolic mechanisms. The primary enzymes involved are aldehyde dehydrogenase (ALDH), alcohol dehydrogenase (ADH), cytochrome P450 (CYP2E1), and catalase. Variations in the genes for these enzymes have been found to influence alcohol consumption, alcohol-related tissue damage, and alcohol dependence. The consequences of alcohol metabolism include oxygen deficits (i.e., hypoxia) in the liver; interaction between alcohol metabolism byproducts and other cell components, resulting in the formation of harmful compounds (i.e., adducts); formation of highly reactive oxygen-containing molecules (i.e., reactive oxygen species [ROS]) that can damage other cell components; changes in the ratio of NADH to NAD+ (i.e., the cell’s redox state); tissue damage; fetal damage; impairment of other metabolic processes; cancer; and medication interactions. Several issues related to alcohol metabolism require further research. KEY WORDS: Ethanol-to acetaldehyde metabolism; alcohol dehydrogenase (ADH); aldehyde dehydrogenase (ALDH); acetaldehyde; acetate; cytochrome P450 2E1 (CYP2E1); catalase; reactive oxygen species (ROS); blood alcohol concentration (BAC); liver; stomach; brain; fetal alcohol effects; genetics and heredity; ethnic group; hypoxia The alcohol elimination rate varies state of liver cells. Chronic alcohol con- he effects of alcohol (i.e., ethanol) widely (i.e., three-fold) among individ- sumption and alcohol metabolism are on various tissues depend on its uals and is influenced by factors such as strongly linked to several pathological concentration in the blood T chronic alcohol consumption, diet, age, consequences and tissue damage. (blood alcohol concentration [BAC]) smoking, and time of day (Bennion and Understanding the balance of alcohol’s over time.