DOCSLIB.ORG

Innovation for Health Research That Makes a Difference

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Innovation for Health Research That Makes a Difference Innovation for health Research that makes a difference TDR biennial report | 2010-2011 Innovation for health Research that makes a difference TDR biennial report | 2010-2011 WHO Library Cataloguing-in-Publication Data Innovation for health: research that makes a difference: TDR biennial report 2010-2011. 1.Tropical medicine. 2.Research. 3.Program evaluation. 4.Strategic planning. 5.Annual reports. I.UNICEF/UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases. ISBN 978 92 4 150356 3 (NLM classification: WC 680) Copyright © World Health Organization on behalf of the Special Programme for Research and Training in Tropical Diseases 2012 All rights reserved. The use of content from this health information product for all non-commercial education, training and information purposes is encouraged, including transla- tion, quotation and reproduction, in any medium, but the content must not be changed and full acknowledgement of the source must be clearly stated. A copy of any resulting product with such content should be sent to TDR, World Health Organization, Avenue Appia, 1211 Geneva 27, Switzerland. TDR is a World Health Organization (WHO) executed UNICEF/UNDP/World Bank/World Health Organiza- tion Special Programme for Research and Training in Tropical Diseases. This information product is not for sale. The use of any information or content whatsoever from it for publicity or advertising, or for any commercial or income- generating purpose, is strictly prohibited. No elements of this information product, in part or in whole, may be used to promote any specific individual, entity or prod- uct, in any manner whatsoever. The designations employed and the presentation of material in this health infor- Compiled and edited by Jamie Guth mation product, including maps and other illustrative materials, do not imply the Design and layout: Lisa Schwarb, Bruno Duret expression of any opinion whatsoever on the part of WHO, including TDR, the au- thors or any parties cooperating in the production, concerning the legal status of Writing: Jamie Guth, Mahnaz Vahedi, Bernard Dichet, Patrick Adams any country, territory, city or area, or of its authorities, or concerning the delinea- Picture credits: pages cover, 4, 10, 14, 21, 29, WHO/TDR/Craggs; tion of frontiers and borders. 6, Yves Leresche; 7, Die Projektoren/DSW; 8, Lucina Schmich; 13, WHO/TDR/ Matlashewski; 15, WHO/TDR/Stammers, WHO/TDR/Crump; Mention or depiction of any specific product or commercial enterprise does not 16-19, Bernard Dichek; 27, Olivier Asselin; 30-31, Brenda Okech; imply endorsement or recommendation by WHO, including TDR, the authors or 32-33, Wilfried Mutombo; 35, Paul Hahn; 37, WHO/TDR/Pagnoni; any parties cooperating in the production, in preference to others of a similar na- 38, WHO/TDR/Schwarb. ture not mentioned or depicted. This report represents the combined efforts of many TDR staff, all of whom are Printed in France. thanked for their invaluable input, comments and support. Contents PART I Foreword by Dr Marie-Paule Kieny, TDR Special Programme Coordinator and Assistant Director-General – Innovation, Information, Evidence and Research, World Health Organization .............. 6 Message from Dr Sue Kinn, Chair of the TDR Joint Coordinating Board .......................................................... 7 Introduction by Dr John Reeder, TDR Director ................................................................................................... 8 PART II Key research achievements ............................................................................................................................. 12 A tale of three villages – A new approach bringing together malaria and pneumonia treatment by community volunteers that could reduce childhood deaths in Africa ...................................................... 16 Ongoing progress ................................................................................................................................................. 20 Stewardship and empowerment ................................................................................................................... 26 Strengthening research capacity where it’s needed most – A profile of the TDR Career Development Fellowship Programme ...................................................................................... 30 Partnerships ........................................................................................................................................................... 34 PART III Key publications and resources .............................................................................................................................. 38 TDR governance and management ........................................................................................................................ 42 STAC membership ..................................................................................................................................................... 45 TDR performance overview for the biennium 2010-2011 .................................................................................. 47 Financial summary .................................................................................................................................................... 50 TDR biennial report | 2010-2011 3 4 PART I Foreword Message Introduction TDR biennial report | 2010–2011 5 Foreword by Dr Marie-Paule Kieny TDR Special Programme Coordinator and Assistant Director-General – Innovation, Information, Evidence and Research, World Health Organization I have worked very closely with TDR’s governing bodies, its senior staff, and most recently, with the new director, John Reeder, to identify and develop new structures that will support the changes. While this has been a challenging time, I also believe it has provided valuable opportunities to try new methods and approaches. TDR has been in transition, but is coming out stronger, leaner, and with a clearer focus on some key areas. I would like to point out that even during this transition, TDR has achieved some impressive results, particularly in the areas of reducing bottlenecks to getting valuable medications and diagnostics to people living in poor, remote areas. This evidence has helped WHO develop new policies that will improve critical services in diseases such as malaria, tuberculosis, dengue and visceral leishmaniasis, This has been an extraordinary two years for TDR, as well as improving healthcare systems. and for me. I became the Assistant Director-General of Innovation, Information, Evidence and Research We are now developing a new strategy that will continue in 2010, which also brings the responsibility of being this tradition of success, albeit in new and innovative TDR’s Special Programme Coordinator. During this ways. This work will provide benefits for people today, time, there has been a great deal of valuable analysis and such as improving the management of African children’s reorganization both at TDR and throughout WHO. The fever – a major killer, and for the next generation as we world is changing and we are looking at new ways to continually expand and improve the local capacity to drive innovation and bring greater access to health care conduct research in the countries where these diseases to those who need it most. cause such a burden. 6 PART I Message from Dr Sue Kinn Chair of the TDR Joint Coordinating Board TDR is a key player and partner for health research on diseases of poverty. Winning the 2011 Gates Award for Global Health lays ample testimony to TDR’s significant record of achievements and the confidence of the global health research community in the continued relevance and importance of TDR. The past two years have been a challenging time for TDR. It became clear that the six year business plan (2008-2013) which foresaw a rapid and continuous growth was too ambitious and needed to be revised. At the beginning of 2011, TDR initiated a reorganization and thorough review of its portfolio of activities. TDR’s governing bodies, the Joint Coordinating Board (JCB), the Standing Committee and the Scientific and Technical Advisory Committee have been actively engaged in the process. I am confident that under the leadership of its new Director, Dr John Reeder, TDR will emerge from this process as a more streamlined Programme focusing on the needs of people afflicted by the diseases of poverty and making sure that the knowledge generated by research is translated into practical health outcomes. TDR has shown itself to be highly adaptable and responsive in the past. With the ongoing support and advice from its partners and stakeholders, such responsiveness will ensure TDR’s continued success and relevance for research on diseases of poverty. TDR biennial report | 2010-2011 7 Introduction by Dr John Reeder TDR Director I am very pleased to be here at TDR. I came at the beginning of the new biennium to find some remarkable successes achieved over the last two years, that you can read about in this report. What I would like to share with you is where TDR is headed. TDR has always stood on solid values – investment in capacity and leadership, driving the science through engagement with people in country, conducting research that meets identified needs – that is its strength. I want to build on this and bring forward into the next stage of TDR a focus on the people and institutions in the countries where these diseases create so many problems.
Load more

Recommended publications
  • CURRICULUM VITAE John William Mcarthur Brookings Institution Global Economy and Development Program 1775 Massachusetts Ave NW Wa
    CURRICULUM VITAE John William McArthur Brookings Institution Global Economy and Development Program 1775 Massachusetts Ave NW Washington, DC 20036 USA t: +1-202-797-6029 e: [email protected] CITIZENSHIP Canada EDUCATION 2009 University of Oxford Doctor of Philosophy in Economics 2000 University of Oxford Master of Philosophy in Economics 1998 Harvard University, John F. Kennedy School of Government Master of Public Policy with concentration in International Trade and Finance 1996 University of British Columbia Bachelor of Arts (1st Class Honours) in Political Science with International Relations PROFESSIONAL APPOINTMENTS 2012 - The Brookings Institution Inaugural Director, Center for Sustainable Development (2020 - ) Senior Fellow, Global Economy and Development (2014 - ) Visiting Fellow, Global Economy and Development (2013 - 2014) Nonresident Senior Fellow, Global Economy and Development (2012 - 2013) 2012 - United Nations Foundation Senior Advisor on Sustainable Development (2016 - ) Senior Fellow (2012 – 2015) 2012 - 2014 Fung Global Institute (Hong Kong) Senior Fellow (2013 - 2014) Senior Advisor (Fall 2012) 2008 - 2011 Millennium Promise Alliance Chief Executive Officer 1 2008 - 2011 Columbia University, School of International and Public Affairs Adjunct Associate Professor (Fall 2011) Adjunct Assistant Professor (Spring 2008 - Spring 2011) 2002 - 2011 Earth Institute at Columbia University Senior Advisor to the Director (2008-2011) Policy Director (2006-2008) Associate Director (2002-2005) 2007 United Nations Development
    [Show full text]
  • April 29 & 30, 2021
    April 29 & 30, 2021 WHAT IS THE REACH ALLIANCE? The Reach Alliance was founded in 2015 The Reach Alliance recruits top students – at the University of Toronto’s Munk equipping the next generation of leaders School of Global Affairs & Public Policy, to produce actionable insights – and in partnership with the Mastercard catalyzes impact through our institutional Center for Inclusive Growth. Inspired partners. Our talented cohort of student by the United Nations’ Sustainable researchers is diverse; since 2015, 63% Development Goals, Reach is a student- have been students of colour, with 19% driven, faculty-mentored research and identifying as Black. Women have made leadership initiative examining how critical up 70% or our cohort, of which 61% have interventions and innovations reach those been women of colour. who are the hardest to reach: those living Our program recruits student leaders in extreme poverty, the geographically across the world’s best universities to remote, administratively invisible and investigate inventive, local solutions to marginalized. Our research has been pressing global challenges. The actionable featured in leading outlets, and our in- insights being generated by the network depth case studies are available on the of universities and companies in the Reach website. Reach Alliance are advancing an inclusive The Reach Alliance is a network of top economy, one that will deliver value to all universities and leading global companies stakeholders while enabling the success of committed to advancing the Sustainable graduates, companies, communities and Development Agenda. Together, we are countries. uncovering the most effective ways to achieve inclusive growth and preparing a generation of leaders with the skills to make it happen.
    [Show full text]
  • From Innovation to Impact ANNUAL REPORT
    ANNUAL REPORT 2017–2018: From Innovation to Impact Grand Challenges Canada / Grands Défis Canada MaRS Centre, West Tower, 661 University Avenue, Suite 1720, Toronto, Ontario M5G 1M1 T +1.416.583.5821 E [email protected] From Innovation to Impact ANNUAL REPORT April 2017 to March 2018 Grand Challenges Canada is funded by: Table of Contents A MESSAGE FROM THE CHAIR OF THE BOARD .................................................................. 4 A MESSAGE FROM THE OUTGOING CHIEF EXECUTIVE OFFICER .................................... 6 A MESSAGE FROM THE INCOMING CO-CHIEF EXECUTIVE OFFICERS ............................ 7 HIGHLIGHTS ............................................................................................................................. 8 Snapshot of 2017–18 ........................................................................................................................ 8 Lives Saved and Improved ................................................................................................................ 8 Key Outputs ..................................................................................................................................... 10 Activities and Inputs ......................................................................................................................... 11 STRATEGIC PLAN .................................................................................................................. 12 Vision and Mission ..........................................................................................................................
    [Show full text]
  • A Platform for Innovation
    Grand Challenges Canada / Grands Défis Canada MaRS Centre, West Tower, 661 University Avenue, Suite 1720, Toronto, Ontario M5G 1M1 T +1.416.583.5821 E [email protected] A Platform for Innovation ANNUAL REPORT April 2016 to March 2017 A Platform for Innovation ANNUAL REPORT 2016–2017 Table of Contents A MESSAGE FROM THE CHAIR OF THE BOARD.................................................................3 A MESSAGE FROM THE CHIEF EXECUTIVE OFFICER.......................................................4 HIGHLIGHTS........................................................................................................................5 Lives Saved and Improved......................................................................................5 Key Outputs.............................................................................................................6 Knowledge Generated..........................................................................................6 Activities and Inputs................................................................................................7 OUR PROGRAMS.................................................................................................................8 Transition To Scale...................................................................................................9 Saving Lives at Birth................................................................................................13 Saving Brains..........................................................................................................16
    [Show full text]
  • Canada's Stars in Global Health Shine from Sea To
    News Release Embargoed until: November 22, 2012 at 2:00 a.m. ET CANADA’S STARS IN GLOBAL HEALTH SHINE FROM SEA TO SEA & WIN FUNDING FROM GRAND CHALLENGES CANADA From cities all across the country, 17 Canadians are selected for their bold out-of-the-box ideas to tackle debilitating disease and save lives in the Developing World Toronto. Grand Challenges Canada, which is funded by the Government of Canada, announced today seed grants awarded to 17 innovators for their bold and creative ideas to tackle health conditions in poor countries. The Stars in Global Health program seeks unique, breakthrough and affordable ideas which can be transformative in addressing disease – innovations that can benefit the developed world as well. The 17 were selected from a total of 60 proposals submitted for the Canadian Stars program. A total of more than $1.7 million in funding will go to innovators from across Canada. The bold ideas are breakthrough innovations such as mimicking rocket propelled technology, but in the body, to address maternal bleeding. A meter to detect HIV infection in fewer than 5 minutes. And a virtual reality game to assist stroke victims. “Canada has a deep pool of talent dedicated to pursuing bold ideas that can have big impact in the developing world,” said Dr. Peter A. Singer, CEO of Grand Challenges Canada. “Grand Challenges Canada is proud to support these extraordinary innovators from across the country because they will make a difference to so many lives.” “Canada works with our like-minded partners throughout the world to leverage our investments in health innovation so they're focused on getting results," said Foreign Affairs Minister John Baird.
    [Show full text]
  • Impact Investing in Canada Four Examples of Impact Investing in Canada Today
    STATE OF THE NATION IMPACT INVESTING IN CANADA FOUR EXAMPLES OF IMPACT INVESTING IN CANADA TODAY 1 2 FIRA FONDs d’INVESTISSEMENT SOLAR SHARE COMMUNITY BOND POUR LA RELÈVE AGRICOLE Created in 2010 by TREC Renewable Energy In 2010, the FONDS de solidarité FTQ, the Government Co-op. Solar Share is a non-profit co-op- of Québec and Desjardins Capital joined to create The erative with a mission to develop commu- Fonds d’investissemnet pour la relève agricole (FIRA), nity-based solar electricity generation in a $75-million private fund established to support Ontario by engaging residents and investors sustainable agriculture and encourage the next gen- in projects that offer tangible financial, so- eration of farmers in Quebec. The program provides cial and environmental returns. Solar Share patient capital in the form of subordinated loans or bonds are backed by 20-year government lease agreements of farmland, allowing young farm- agreements under Ontario’s Feed-in Tariff ers time to establish their agricultural business in program and are secured by mortgages on the early years. Property acquisition by FIRA allows title. Ontario residents who become Solar for 15-year leases with exclusive right of redemption Share Co-op members can purchase the through entire lease. bonds on a five-year term. Learn more: www.lefira.ca Learn more: www.solarbonds.ca 3 4 RENEWAL3 RBC GENERATOR FUND Renewal3 is part of Renewal Funds; it was started by The RBC Generator Fund was established Carol Newell and Joel Solomon, who met through a in 2012, as a $10-million pool of capital to network of individuals using wealth for good.
    [Show full text]
  • Bid Solicitation Innovation Portfolio Sensemaking
    BID SOLICITATION Grand Challenges Canada MaRS Centre, West Tower, 661 University Avenue, Suite 1720, Toronto, Ontario, Canada M5G 1M1 T 416.583.5821 E [email protected] Bid Solicitation Innovation Portfolio Sensemaking Submission Deadline: 27 January 2020 – 17:00 ET RFP Reference Number: RFP-2020-01-02 1 Part 1: Introduction 1.1 Grand Challenges Canada’s Objective Grand Challenges Canada is seeking assistance with its activities to nurture the scalability and sustainability of global health innovations that Grand Challenges Canada supports. The objective of this bid solicitation (“Bid Solicitation”) is to select vendor(s) to enter into a contract with Grand Challenges Canada to provide the services described in the Statement of Work, as defined in Appendix A. Appendix B defines the evaluation criteria that will be used during the selection process. 1.2 About Grand Challenges Canada Grand Challenges Canada is dedicated to supporting Bold Ideas with Big Impact®. Funded by the Government of Canada and other partners, Grand Challenges Canada funds innovators in low- and middle-income countries and Canada. The bold ideas Grand Challenges Canada supports integrate science and technology, social and business innovation – known as Integrated Innovation®. One of the largest impact-first investors in Canada, and with a feminist investment approach, Grand Challenges Canada has supported a pipeline of over 1200 innovations in more than 85 countries. Grand Challenges Canada estimates that these innovations have the potential to save up to 1.6 million lives and improve up to 51 million lives by 2030. Grand Challenges Canada is hosted in Toronto at the Sandra Rotman Centre at the University Health Network.
    [Show full text]
  • Annual Report 2019–20
    ANNUAL REPORT 2019–20 CELEBRATING 10 YEARS OF BOLD IDEAS WITH BIG IMPACT ® TTaabbllee ooff CCoonntteennttss A Message from the Chair of the Board 1 of Directors A Message from our Co-CEOs 3 10 Years of Impact – by the Numbers 7 Rotman Innovation of the Year Award 8 Stories of Impact 9 Management Discussion and Analysis 11 Financial Highlights 16 To learn more about the past decade of growth,, visit our interactive impact report at: www.grandchallenges.ca/see-our-impact CELEBRATING 10 YEARS OF BOLD IDEAS WITH BIG IMPACT® i AA MMeessssaaggee ffrroomm tthhee CChhaaiirr ooff tthhee BBooaarrdd ooff DDiirreeccttoorrss It has been a distinct pleasure to chair the Board of Directors over the past year—a 10th- anniversary year that has been an important one for Grand Challenges Canada. Celebrate the past, embrace the future While Grand Challenges Canada’s mandate has expanded to three areas of impact over the last decade (Development, Humanitarian and Indigenous) our underlying principles have remained the same—underlying principles that were defined by inspirational leaders. We remember founding Chair Joseph Rotman, who saw the potential of Grand Challenges Canada in being a platform to catalyze innovative approaches that need support and money to get going, but which could sustain life-saving impacts long after our last dollar has been invested. His passion for entrepreneurship and philanthropy inspired Grand Challenge Canada’s approach of Integrated Innovation® – the coordinated application of scientific/technological, social and business innovation to develop solutions to complex challenges. We remember founding Board member Allan Gotlieb, who sadly passed away earlier this year.
    [Show full text]
  • Saving Brains Identify Early Life Interventions That Promote the Fulfillment of Human Capital May 2011
    REQUEST FOR PROPOSALS Grand Challenges Canada at the McLaughlin-Rotman Centre for Global Health Saving Brains Identify early life interventions that promote the fulfillment of human capital May 2011 Executive Summary Grand Challenges Canada is creating an initiative to promote the fulfillment of human capital by focusing on interventions administered in the first thousand days of development – between conception and two years of age. Over 200 million children fail to reach their full cognitive developmental potential. Poverty is both a cause and a result of this failure. This creates a vicious cycle whereby malnutrition, infection, poor management of pregnancy and birth complications, and a lack of cognitive stimulation and nurturing before two years of age—all risks to cognitive development—have long- lasting effects that decrease productivity in adulthood. In parallel with strengthening of health systems and tackling broader determinants of poor health, interventions targeted against these risk factors in the first thousand days have the potential to increase the productive wealth embodied in the intellectual, social and physical capability of the individual, which is key to the development of individuals, communities, and whole societies. The ultimate aim of this initiative is to identify and develop effective and efficient means to promote cognitive development in the first thousand days with lasting impact on human capital in low- and middle-income countries. This request for proposals solicits proposals for projects that evaluate the long-term effect of interventions delivered in the first thousand days of development on human capital by re-enrollment and assessment of cohorts who have participated in intervention studies.
    [Show full text]
  • Saving Brains May 2016
    REQUEST FOR PROPOSALS Grand Challenges Canada at the Sandra Rotman Centre MaRS Centre, South Tower, 101 College Street, Suite 406, Toronto, Ontario, Canada M5G 1L7 T 416.673.6568 F 416.978.6826 E [email protected] Saving Brains May 2016 [Updated July 15, 2016] Executive Summary Early child development is an essential part of building healthy, productive societies where children both survive and thrive. A world where girls and boys thrive is envisioned through the Sustainable Development Goals for nutrition, education, health, peace and conflict, and is central to the UN Secretary General’s Global Strategy for Women’s, Children’s and Adolescent’s Health (2016–2030). An individual’s developmental path is shaped by the interaction of the genes they possess and the experiences and environment to which they are exposed – especially early in life. Living in poverty increases the exposure to a number of adverse experiences and environments that can pose a risk to healthy development. These risk factors can include poor management of birth complications, lack of consistent and nurturing interactions, exposure to violence or neglect, malnutrition, severe or chronic infections, exposure to environmental toxins, and other sources of toxic stress. Failure to nurture children and protect them from these risks erodes the right of millions of children to develop to their full potential. It is also a devastating waste of human capital that leaves the next generation ill-equipped to solve the enormous challenges that lock individuals, communities and societies in poverty. With the ultimate goal of increasing human capital and tackling existing inequalities, Saving Brains seeks bold ideas for products, services and implementation models that protect and nurture early brain development in a sustainable manner.
    [Show full text]
  • Evidence-Based Innovation
    Grand Challenges Canada at the Sandra Rotman Centre MaRS Centre, South Tower, 101 College Street, Suite 406, Toronto, Ontario, Canada M5G 1L7 T 416.673.6568 F 416.978.6826 E [email protected] Evidence-based Innovation ANNUAL REPORT April 2015 to March 2016 Evidence-based Innovation ANNUAL REPORT 2015–2016 Table of Contents A MESSAGE FROM THE CHAIR OF THE BOARD........................................................3 A MESSAGE FROM THE CHIEF EXECUTIVE OFFICER................................................4 HIGHLIGHTS 2015–2016.................................................................................................5 Lives Saved and Improved......................................................................................5 Policies Influenced.................................................................................................5 Knowledge Generated..........................................................................................6 Next Generation of Innovators Supported...........................................................7 Activities and Inputs................................................................................................7 Distribution of Innovations.................................................................................8 OUR PROGRAMS................................................................................................................9 Strategic Priorities and Portfolio.......................................................................9 Transition To Scale.............................................................................................10
    [Show full text]
  • Challenges Faced by Multidisplinary New Investigators On
    TSpace Research Repository tspace.library.utoronto.ca Challenges faced by multidisplinary new investigators on addressing grand challenges in global health Carmen Logie, Helen Dimaras, Anny Fortin, & Santiago Ramón-García Version Published Version/ Final PDF Citation Logie, C., et al. (2014). Challenges faced by multidisciplinary new (published version) investigators on addressing grand challenges in global health. Globalization and Health 10(1): 27. doi: 10.1186/1744-8603-10-27. Copyright / License CC BY 4.0 How to cite TSpace items Always cite the published version, so the author(s) will receive recognition through services that track citation counts, e.g. Scopus. If you need to cite the page number of the TSpace version (original manuscript or accepted manuscript) because you cannot access the published version, then cite the TSpace version in addition to the published version using the permanent URI (handle) found on the record page. Logie et al. Globalization and Health 2014, 10:27 http://www.globalizationandhealth.com/content/10/1/27 DEBATE Open Access Challenges faced by multidisplinary new investigators on addressing grand challenges in global health Carmen Logie1,2†, Helen Dimaras3,4,5,10*†, Anny Fortin6,7,11† and Santiago Ramón-García8,9,12† Abstract Background: The grand challenges approach aims to spark innovative and transformative strategies to overcome barriers to significant global health issues. Grand Challenges Canada endorses an ‘Integrated Innovation™’ approach that focuses on the intersection of scientific/technological, social and business innovation. In this article we explore themes emerging from a dialogue between the authors, who are multidisciplinary recipients of the ‘Rising Stars in Global Health’ award from Grand Challenges Canada, regarding benefits of engaging in integrated innovation research, and recommendations for how this approach may develop in the future.
    [Show full text]