World Journal of W J C C Clinical Cases Submit a Manuscript: http://www.wjgnet.com/esps/ World J Clin Cases 2014 December 16; 2(12): 866-872 Help Desk: http://www.wjgnet.com/esps/helpdesk.aspx ISSN 2307-8960 (online) DOI: 10.12998/wjcc.v2.i12.866 © 2014 Baishideng Publishing Group Inc. All rights reserved. MINIREVIEWS Precancerous lesions of oral mucosa Gurkan Yardimci, Zekayi Kutlubay, Burhan Engin, Yalcin Tuzun Gurkan Yardimci, Department of Dermatology, Muş State Hos- alternatives such as corticosteroids, calcineurin inhibi- pital, 49100 Muş, Turkey tors, and retinoids are widely used. Zekayi Kutlubay, Burhan Engin, Yalcin Tuzun, Department of Dermatology, Cerrahpaşa Medical Faculty, Istanbul University, © 2014 Baishideng Publishing Group Inc. All rights reserved. 34098 Istanbul, Turkey Author contributions: Kutlubay Z designed research; Yardımci Key words: Oral premalignant lesions; Leukoplakia; G performed research; Tuzun Y contributed new reagents or ana- Erythroplakia; Submucous fibrosis; Lichen planus; Ma- lytic tools; Engin B analyzed data; Yardımci G wrote the paper. Correspondence to: Zekayi Kutlubay, MD, Department of lignant transformation Dermatology, Cerrahpaşa Medical Faculty, Istanbul University, Cerrah Paşa Mh., 34098 Istanbul, Core tip: Precancerous lesions of oral mucosa are the Turkey.
[email protected] diseases that have malignant transformation risk at dif- Telephone: +90-212-4143120 Fax: +90-212-4147156 ferent ratios. Clinically, these diseases may sometimes Received: July 22, 2014 Revised: August 28, 2014 resemble each other. Thus, the diagnosis should be Accepted: September 23, 2014 confirmed by biopsy. In early stages, histopathological Published online: December 16, 2014 findings are distinctive, but if malignant transformation occurs, identical histological features with oral carci- noma are seen.