DOCSLIB.ORG

Human Population History and Its Interplay with Natural Selection

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Human Population History and Its Interplay with Natural Selection Human population history and its interplay with natural selection Veronika Siska Department of Zoology University of Cambridge This dissertation is submitted for the degree of Doctor of Philosophy Trinity College 2018 September Human population history and its interplay with natural selection Veronika Siska Summary The complex demographic changes that underlie the expansion of anatomically modern humans out of Africa have important consequences on the dynamics of natural selection and our ability to detect it. In this thesis, I aimed to refine our knowledge on human population history using ancient genomes, and then used a climate-informed, spatially explicit framework to explore the interplay between complex demographies and selection. I first analysed a high-coverage genome from Upper Palaeolithic Romania from ~37.8 kya, and demonstrated an early diversification of multiple lineages shortly after the out-of-Africa expansion (Chapter 2). I then investigated Late Upper Palaeolithic (~13.3ky old) and Mesolithic (~9.7 ky old) samples from the Caucasus and a Late Upper Palaeolithic (~13.7ky old) sample from Western Europe, and found that these two groups belong to distinct lineages that also diverged shortly after the out of Africa, ~45-60 ky ago (Chapter 3). Finally, I used East Asian samples from ~7.7ky ago to show that there has been a greater degree of genetic continuity in this region compared to Europe (Chapter 4). In the second part of my thesis, I used a climate-informed, spatially explicit demographic model that captures the out-of-Africa expansion to explore natural selection. I first investigated whether the model can represent the confounding effect of demography on selection statistics, when applied to neutral part of the genome (Chapter 5). Whilst the overlap between different selection statistics was somewhat underestimated by the model, the relationship between signals from different populations is generally well-captured. I then modelled natural selection in the same framework and investigated the spatial distribution of two genetic variants associated with a protective effect against malaria, sickle-cell anaemia and β0 thalassemia (Chapter 6). I found that although this model can reproduce the disjoint ranges of different variants typical of the former, it is incompatible with overlapping distributions characteristic of the latter. Furthermore, our model is compatible with the inferred single origin of sickle-cell disease in most regions, but it can not reproduce the presence of this disorder in India without long-distance migrations. ii Declaration This dissertation is the result of my own work and includes nothing which is the outcome of work done in collaboration except as declared in the Preface and specified in the text. It is not substantially the same as any that I have submitted, or, is being concurrently submitted for a degree or diploma or other qualification at the University of Cambridge or any other University or similar institution except as specified in the text. I further state that no substantial part of my dissertation has already been submitted, or, is being concurrently submitted for any such degree, diploma or other qualification at the University of Cambridge or any other University or similar institution. The main text does not exceed the prescribed word limit for the relevant Degree Committee (School of Biology). Veronika Siska 2018 September iii Acknowledgements I would like to give my thanks to the many people in many countries who I met through my PhD journey and without whom the work presented in this thesis would not have been possible. First and foremost, I would like to thank my supervisor, Andrea Manica. Thank you for your continuous support, your understanding and your advice in both academic matters and regarding general life issues. Thank you also for your trust and for giving me the freedom to explore my ideas. I am also grateful for the continuous support of the postdocs in our group – without them, this PhD would have been a very lonely experience. Thank you, Eppie, for your guidance on ancient DNA, for my first, fully positive experience about collaborative research, and for your incredible support when I was searching for my path. I also want to thank Anders for creating the model I could build on; Pier for his warm support (especially in the last, frantic period) and the many useful discussions and Mario and Robert for their effort on modelling. I would like to also thank my advisors, Chris Jiggins and John Welch for insightful comments on my project. Another warm thank goes to those who have given their time to read through my thesis and make sure it is actually in English: to Philipp, Eppie, Pier, Anne-Sophie and Riva. I am also grateful for all of the organisations who supported me. The Gates Cambridge Trust provided the financial basis that enabled me to conduct this research and attend conferences. Even more importantly, the Trust provided a stimulating environment through workshops on general humanitarian and personal development topics and by acting as a platform to meet with like-minded scholars. I also would like to thank the Cambridge Philosophical Society for their financial help in the last year of my PhD studies. Lastly, living in Cambridge would not have been such an incredible, unique experience without my college, Trinity, who not only helped me financially, but was also my home for over three years. In particular, the support of my college tutor, David Spring, the lively discussions over dinner on the Trinity Biology Seminars and the warmth and helpfulness of every member of the college staff made me feel welcome in Cambridge and at Trinity College. The Department of Zoology and the Evolutionary Ecology Lab provided the basis of all of my academic work. The frequent coffee breaks, happy hours, talks showcasing various animals and the odd lunch meeting created a lovely working space. I am grateful for the staff iv to make all of our work possible and feel honoured to have met so many incredible people at Zoology: Riva, Anne-Sophie, Eppie, Pier, Anahit, Robert, Mario, Tim, Anders, Maddie, Maanasa, Lizzie, Alison, James, Jim, Arne and so many others. Such an environment made it possible to keep focused and bounce back at the inevitable downs - I will miss everyone! I also would like to thank my friends who had my back through these exciting, but often challenging years. In Cambridge, Anne-Sophie helped me manage my own expectations and demonstrated that work-life balance is possible, Riva showed what being passionate about a research topic really is like and Young Mi was always there when things were not going according to plan. Another warm thanks goes to David for his support; Konrad for helping me find a job; Daniel, Tim and Lawrence, my climbing companions, and to all the friendly Trinitarians, Zoologists and other Cambridge residents I’ve met. Special thanks to all of my friends in Budapest who made the effort to keep in touch with me through my ever-changing life, visited me and met with me at home: Péter, Szilvi, Laura, Bence and Bálint kept me in touch with “real life” beyond Cambridge. Finally, I am eternally grateful for my family for supporting me in a foreign environment and for giving me the strong roots that I could rely on. This PhD was an incredible journey leading to new destinations. I would like to dedicate my thesis to those closest to me who helped me find my own way: to my parents, Éva and Péter, and to my partner, Philipp. v Contents Contents .................................................................................................................................... vi Chapter 1 General introduction .......................................................................................... 11 1.1 History of anatomically modern humans .................................................................. 11 1.1.1 Evolution of anatomically modern humans ....................................................... 11 1.1.2 The expansion of anatomically modern humans out of Africa .......................... 13 1.1.3 Neolithic transition............................................................................................. 15 1.2 Genome sequencing .................................................................................................. 16 1.2.1 Introduction to genome sequencing ................................................................... 16 1.2.2 Ancient DNA ..................................................................................................... 17 1.3 Modelling .................................................................................................................. 19 1.3.1 Demography ....................................................................................................... 19 1.3.2 Genetics.............................................................................................................. 20 1.4 Natural selection ........................................................................................................ 22 1.4.1 Introduction to natural selection ........................................................................ 22 1.4.2 Confounding effects ........................................................................................... 23 1.5 Bibliography .............................................................................................................. 24 Chapter 2 Palaeolithic Oase genome implies diversification and extinction events across
Load more

Recommended publications
  • Region Country County/Prov Ince 1 As
    Locality Decimal Decimal Elevation (m County/prov No. Locality Subsite/stratum latitude longitude asl.) Region Country ince 1 Asdal 57,4666 9,9833 60 North DK Jutland 2 Nørre Lyngby A 57,4000 9,7000 North DK Jutland 2 Nørre Lyngby A 57,4000 9,7000 North DK Jutland 2 Nørre Lyngby A 57,4000 9,7000 North DK Jutland 2 Nørre Lyngby A 57,4000 9,7000 North DK Jutland 2 Nørre Lyngby A 57,4000 9,7000 North DK Jutland 2 Nørre Lyngby A 57,4000 9,7000 North DK Jutland 2 Nørre Lyngby A 57,4000 9,7000 North DK Jutland 2 Nørre Lyngby A 57,4000 9,7000 North DK Jutland 2 Nørre Lyngby A 57,4000 9,7000 North DK Jutland 2 Nørre Lyngby A 57,4000 9,7000 North DK Jutland 2 Nørre Lyngby A 57,4000 9,7000 North DK Jutland 2 Nørre Lyngby A 57,4000 9,7000 North DK Jutland 2 Nørre Lyngby A 57,4000 9,7000 North DK Jutland 2 Nørre Lyngby A 57,4000 9,7000 North DK Jutland 2 Nørre Lyngby B 57,4000 9,7000 North DK Jutland 2 Nørre Lyngby B 57,4000 9,7000 North DK Jutland 2 Nørre Lyngby B 57,4000 9,7000 North DK Jutland 2 Nørre Lyngby B 57,4000 9,7000 North DK Jutland 2 Nørre Lyngby B,C 57,4000 9,7000 North DK Jutland 2 Nørre Lyngby C 57,4000 9,7000 North DK Jutland 2 Nørre Lyngby C 57,4000 9,7000 North DK Jutland 2 Nørre Lyngby C 57,4000 9,7000 North DK Jutland 2 Nørre Lyngby D 57,4000 9,7000 North DK Jutland 2 Nørre Lyngby general 57,4000 9,7000 North DK Jutland 2 Nørre Lyngby 57,4000 9,7000 North DK Jutland 2 Nørre Lyngby 57,4000 9,7000 North DK Jutland 2 Nørre Lyngby 57,4000 9,7000 North DK Jutland 2 Nørre Lyngby 57,4000 9,7000 North DK Jutland 2 Nørre Lyngby 57,4000
    [Show full text]
  • Tentative Lists Submitted by States Parties As of 15 April 2021, in Conformity with the Operational Guidelines
    World Heritage 44 COM WHC/21/44.COM/8A Paris, 4 June 2021 Original: English UNITED NATIONS EDUCATIONAL, SCIENTIFIC AND CULTURAL ORGANIZATION CONVENTION CONCERNING THE PROTECTION OF THE WORLD CULTURAL AND NATURAL HERITAGE WORLD HERITAGE COMMITTEE Extended forty-fourth session Fuzhou (China) / Online meeting 16 – 31 July 2021 Item 8 of the Provisional Agenda: Establishment of the World Heritage List and of the List of World Heritage in Danger 8A. Tentative Lists submitted by States Parties as of 15 April 2021, in conformity with the Operational Guidelines SUMMARY This document presents the Tentative Lists of all States Parties submitted in conformity with the Operational Guidelines as of 15 April 2021. • Annex 1 presents a full list of States Parties indicating the date of the most recent Tentative List submission. • Annex 2 presents new Tentative Lists (or additions to Tentative Lists) submitted by States Parties since 16 April 2019. • Annex 3 presents a list of all sites included in the Tentative Lists of the States Parties to the Convention, in alphabetical order. Draft Decision: 44 COM 8A, see point II I. EXAMINATION OF TENTATIVE LISTS 1. The World Heritage Convention provides that each State Party to the Convention shall submit to the World Heritage Committee an inventory of the cultural and natural sites situated within its territory, which it considers suitable for inscription on the World Heritage List, and which it intends to nominate during the following five to ten years. Over the years, the Committee has repeatedly confirmed the importance of these Lists, also known as Tentative Lists, for planning purposes, comparative analyses of nominations and for facilitating the undertaking of global and thematic studies.
    [Show full text]
  • Discovery of the Fuyan Teeth: Challenging Or Complementing the Out-Of-Africa Scenario?
    ZOOLOGICAL RESEARCH Discovery of the Fuyan teeth: challenging or complementing the out-of-Africa scenario? Yu-Chun LI, Jiao-Yang TIAN, Qing-Peng KONG Although it is widely accepted that modern humans (Homo route about 40-60 kya (Macaulay et al, 2005; Sun et al, 2006). sapiens sapiens) can trace their African origins to 150-200 kilo The lack of human fossils dating earlier than 70 kya in eastern years ago (kya) (recent African origin model; Henn et al, 2012; Eurasia implies that the out-of-Africa immigrants around 100 Ingman et al, 2000; Poznik et al, 2013; Weaver, 2012), an kya likely failed to expand further east (Shea, 2008). Consistent alternative model suggests that the diverse populations of our with this notion, the Late Pleistocene hominid records species evolved separately on different continents from archaic previously found in eastern Eurasia have been dated to only human forms (multiregional origin model; Wolpoff et al, 2000; 40-70 kya, including the Liujiang man (67 kya; Shen et al, 2002) Wu, 2006). The recent discovery of 47 teeth from a Fuyan cave and Tianyuan man (40 kya; Fu et al, 2013b; Shang et al, 2007) in southern China (Liu et al, 2015) indicated the presence of H. in China, the Mungo Man in Australia (40-60 kya; Bowler et al, s. sapiens in eastern Eurasia during the early Late Pleistocene. 1972), the Niah Cave skull from Borneo (40 kya; Barker et al, Since the age of the Fuyan teeth (80-120 kya) predates the 2007) and the Tam Pa Ling cave man in Laos (46-51 kya; previously assumed out-of-Africa exodus (60 kya) by at least 20 Demeter et al, 2012).
    [Show full text]
  • Curriculum Vitae Erik Trinkaus
    9/2014 Curriculum Vitae Erik Trinkaus Education and Degrees 1970-1975 University of Pennsylvania Ph.D 1975 Dissertation: A Functional Analysis of the Neandertal Foot M.A. 1973 Thesis: A Review of the Reconstructions and Evolutionary Significance of the Fontéchevade Fossils 1966-1970 University of Wisconsin B.A. 1970 ACADEMIC APPOINTMENTS Primary Academic Appointments Current 2002- Mary Tileston Hemenway Professor of Arts & Sciences, Department of Anthropolo- gy, Washington University Previous 1997-2002 Professor: Department of Anthropology, Washington University 1996-1997 Regents’ Professor of Anthropology, University of New Mexico 1983-1996 Assistant Professor to Professor: Dept. of Anthropology, University of New Mexico 1975-1983 Assistant to Associate Professor: Department of Anthropology, Harvard University MEMBERSHIPS Honorary 2001- Academy of Science of Saint Louis 1996- National Academy of Sciences USA Professional 1992- Paleoanthropological Society 1990- Anthropological Society of Nippon 1985- Société d’Anthropologie de Paris 1973- American Association of Physical Anthropologists AWARDS 2013 Faculty Mentor Award, Graduate School, Washington University 2011 Arthur Holly Compton Award for Faculty Achievement, Washington University 2005 Faculty Mentor Award, Graduate School, Washington University PUBLICATIONS: Books Trinkaus, E., Shipman, P. (1993) The Neandertals: Changing the Image of Mankind. New York: Alfred A. Knopf Pub. pp. 454. PUBLICATIONS: Monographs Trinkaus, E., Buzhilova, A.P., Mednikova, M.B., Dobrovolskaya, M.V. (2014) The People of Sunghir: Burials, Bodies and Behavior in the Earlier Upper Paleolithic. New York: Ox- ford University Press. pp. 339. Trinkaus, E., Constantin, S., Zilhão, J. (Eds.) (2013) Life and Death at the Peştera cu Oase. A Setting for Modern Human Emergence in Europe. New York: Oxford University Press.
    [Show full text]
  • Reports on Completed Research for 2014
    Reports on Completed Research for 2014 “Supporting worldwide research in all branches of Anthropology” REPORTS ON COMPLETED RESEARCH The following research projects, supported by Foundation grants, were reported as complete during 2014. The reports are listed by subdiscipline, then geographic area (where applicable) and in alphabetical order. A Bibliography of Publications resulting from Foundation-supported research (reported over the same period) follows, along with an Index of Grantees Reporting Completed Research. ARCHAEOLOGY Africa: DR. JAMIE LYNN CLARK, University of Alaska, Fairbanks, Alaska, received a grant in April 2013 to aid research on “The Sibudu Fauna: Implications for Understanding Behavioral Variability in the Southern African Middle Stone Age.” This project sought to gain a deeper understanding of human behavioral variability during the Middle Stone Age through the analysis of the Still Bay (SB; ~71,000 ya) and pre-SB (>72,000 ya) fauna from Sibudu Cave. In addition to characterizing variation in human hunting behavior within and between the two periods, the project had two larger goals. First, to explore whether the data were consistent with hypotheses linking the appearance of the SB to environmental change. No significant changes in the relative frequency of open vs. closed dwelling species were identified, with species preferring closed habitats predominant throughout. This suggests that at Sibudu, the onset of the SB was not correlated with climate change. Secondly, data collected during this project will be combined with lithic and faunal data from later deposits at Sibudu in order to explore the relationship between subsistence and technological change spanning from the pre-SB through the post-Howiesons Poort MSA (~58,000 ya).
    [Show full text]
  • Direct Dating of Neanderthal Remains from the Site of Vindija Cave and Implications for the Middle to Upper Paleolithic Transition
    Direct dating of Neanderthal remains from the site of Vindija Cave and implications for the Middle to Upper Paleolithic transition Thibaut Devièsea,1, Ivor Karavanicb,c, Daniel Comeskeya, Cara Kubiaka, Petra Korlevicd, Mateja Hajdinjakd, Siniša Radovice, Noemi Procopiof, Michael Buckleyf, Svante Pääbod, and Tom Highama aOxford Radiocarbon Accelerator Unit, Research Laboratory for Archaeology and the History of Art, University of Oxford, Oxford OX1 3QY, United Kingdom; bDepartment of Archaeology, Faculty of Humanities and Social Sciences, University of Zagreb, HR-10000 Zagreb, Croatia; cDepartment of Anthropology, University of Wyoming, Laramie, WY 82071; dDepartment of Evolutionary Genetics, Max-Planck-Institute for Evolutionary Anthropology, D-04103 Leipzig, Germany; eInstitute for Quaternary Palaeontology and Geology, Croatian Academy of Sciences and Arts, HR-10000 Zagreb, Croatia; and fManchester Institute of Biotechnology, University of Manchester, Manchester M1 7DN, United Kingdom Edited by Richard G. Klein, Stanford University, Stanford, CA, and approved July 28, 2017 (received for review June 5, 2017) Previous dating of the Vi-207 and Vi-208 Neanderthal remains from to directly dating the remains of late Neanderthals and early Vindija Cave (Croatia) led to the suggestion that Neanderthals modern humans, as well as artifacts recovered from the sites they survived there as recently as 28,000–29,000 B.P. Subsequent dating occupied. It has become clear that there have been major pro- yielded older dates, interpreted as ages of at least ∼32,500 B.P. We blems with dating reliability and accuracy across the Paleolithic have redated these same specimens using an approach based on the in general, with studies highlighting issues with underestimation extraction of the amino acid hydroxyproline, using preparative high- of the ages of different dated samples from previously analyzed performance liquid chromatography (Prep-HPLC).
    [Show full text]
  • Annotated Atlatl Bibliography John Whittaker Grinnell College Version June 20, 2012
    1 Annotated Atlatl Bibliography John Whittaker Grinnell College version June 20, 2012 Introduction I began accumulating this bibliography around 1996, making notes for my own uses. Since I have access to some obscure articles, I thought it might be useful to put this information where others can get at it. Comments in brackets [ ] are my own comments, opinions, and critiques, and not everyone will agree with them. The thoroughness of the annotation varies depending on when I read the piece and what my interests were at the time. The many articles from atlatl newsletters describing contests and scores are not included. I try to find news media mentions of atlatls, but many have little useful info. There are a few peripheral items, relating to topics like the dating of the introduction of the bow, archery, primitive hunting, projectile points, and skeletal anatomy. Through the kindness of Lorenz Bruchert and Bill Tate, in 2008 I inherited the articles accumulated for Bruchert’s extensive atlatl bibliography (Bruchert 2000), and have been incorporating those I did not have in mine. Many previously hard to get articles are now available on the web - see for instance postings on the Atlatl Forum at the Paleoplanet webpage http://paleoplanet69529.yuku.com/forums/26/t/WAA-Links-References.html and on the World Atlatl Association pages at http://www.worldatlatl.org/ If I know about it, I will sometimes indicate such an electronic source as well as the original citation. The articles use a variety of measurements. Some useful conversions: 1”=2.54
    [Show full text]
  • Agricultural Practices in Ancient Macedonia from the Neolithic to the Roman Period
    View metadata, citation and similar papers at core.ac.uk brought to you by CORE provided by International Hellenic University: IHU Open Access Repository Agricultural practices in ancient Macedonia from the Neolithic to the Roman period Evangelos Kamanatzis SCHOOL OF HUMANITIES A thesis submitted for the degree of Master of Arts (MA) in Black Sea and Eastern Mediterranean Studies January 2018 Thessaloniki – Greece Student Name: Evangelos Kamanatzis SID: 2201150001 Supervisor: Prof. Manolis Manoledakis I hereby declare that the work submitted is mine and that where I have made use of another’s work, I have attributed the source(s) according to the Regulations set in the Student’s Handbook. January 2018 Thessaloniki - Greece Abstract This dissertation was written as part of the MA in Black Sea and Eastern Mediterranean Studies at the International Hellenic University. The aim of this dissertation is to collect as much information as possible on agricultural practices in Macedonia from prehistory to Roman times and examine them within their social and cultural context. Chapter 1 will offer a general introduction to the aims and methodology of this thesis. This chapter will also provide information on the geography, climate and natural resources of ancient Macedonia from prehistoric times. We will them continue with a concise social and cultural history of Macedonia from prehistory to the Roman conquest. This is important in order to achieve a good understanding of all these social and cultural processes that are directly or indirectly related with the exploitation of land and agriculture in Macedonia through time. In chapter 2, we are going to look briefly into the origins of agriculture in Macedonia and then explore the most important types of agricultural products (i.e.
    [Show full text]
  • LAMPEA-Doc 2015 – Numéro 37
    Laboratoire méditerranéen de Préhistoire (Europe – Afrique) Bibliothèque LAMPEA-Doc 2015 – numéro 37 vendredi 11 décembre 2015 [Se désabonner >>>] Suivez les infos en continu en vous abonnant au fil RSS http://lampea.cnrs.fr/spip.php?page=backend ou sur Twitter @LampeaDoc https://twitter.com/LampeaDoc 1 - Congrès, colloques, réunions - Modern origins in the Mediterranean : interdisciplinary approach - 5èmes Journées « informatique et archéologie » de Paris (JIAP 2016) - Mining and Quarrying - Points d’eau et dynamiques des paysages au Quaternaire en Afrique du Nord 2 - Emplois, bourses, prix, stages - Assistante de gestion en archéologie - La ville de Poitiers recrute un conservateur en archéologie (préhistorique et protohistorique) - L'Office Allemand d’Echanges Universitaires de Paris soutient les étudiants … - Poste d’animateur d’ateliers préhistoriques pour scolaires 3 - Site web - Carnivore Ecology & Conservation : e-resources for scientists and conservationists - Jurn directory : 4000 revues en accès libre en SHS 4 - Acquisitions bibliothèque La semaine prochaine Congrès, colloques, réunions Séminaire 2015-2016 "Archéologie et histoire de l'Afrique" : Diversité et coexistence des systèmes sociaux, techniques et économiques http://lampea.cnrs.fr/spip.php?article3392 du 14 octobre 2015 au 16 décembre 2015 Université de Toulouse : Maison de la Recherche TAG 2015 (Theoretical Archaeology Group) http://lampea.cnrs.fr/spip.php?article3430 14-16 december 2015 Bradford Statistiques et modèles en archéométrie et en archéologie http://lampea.cnrs.fr/spip.php?article3445
    [Show full text]
  • Geographic Names
    GEOGRAPHIC NAMES CORRECT ORTHOGRAPHY OF GEOGRAPHIC NAMES ? REVISED TO JANUARY, 1911 WASHINGTON GOVERNMENT PRINTING OFFICE 1911 PREPARED FOR USE IN THE GOVERNMENT PRINTING OFFICE BY THE UNITED STATES GEOGRAPHIC BOARD WASHINGTON, D. C, JANUARY, 1911 ) CORRECT ORTHOGRAPHY OF GEOGRAPHIC NAMES. The following list of geographic names includes all decisions on spelling rendered by the United States Geographic Board to and including December 7, 1910. Adopted forms are shown by bold-face type, rejected forms by italic, and revisions of previous decisions by an asterisk (*). Aalplaus ; see Alplaus. Acoma; township, McLeod County, Minn. Abagadasset; point, Kennebec River, Saga- (Not Aconia.) dahoc County, Me. (Not Abagadusset. AQores ; see Azores. Abatan; river, southwest part of Bohol, Acquasco; see Aquaseo. discharging into Maribojoc Bay. (Not Acquia; see Aquia. Abalan nor Abalon.) Acworth; railroad station and town, Cobb Aberjona; river, IVIiddlesex County, Mass. County, Ga. (Not Ackworth.) (Not Abbajona.) Adam; island, Chesapeake Bay, Dorchester Abino; point, in Canada, near east end of County, Md. (Not Adam's nor Adams.) Lake Erie. (Not Abineau nor Albino.) Adams; creek, Chatham County, Ga. (Not Aboite; railroad station, Allen County, Adams's.) Ind. (Not Aboit.) Adams; township. Warren County, Ind. AJjoo-shehr ; see Bushire. (Not J. Q. Adams.) Abookeer; AhouJcir; see Abukir. Adam's Creek; see Cunningham. Ahou Hamad; see Abu Hamed. Adams Fall; ledge in New Haven Harbor, Fall.) Abram ; creek in Grant and Mineral Coun- Conn. (Not Adam's ties, W. Va. (Not Abraham.) Adel; see Somali. Abram; see Shimmo. Adelina; town, Calvert County, Md. (Not Abruad ; see Riad. Adalina.) Absaroka; range of mountains in and near Aderhold; ferry over Chattahoochee River, Yellowstone National Park.
    [Show full text]
  • Sacred Places Europe: 108 Destinations
    Reviews from Sacred Places Around the World “… the ruins, mountains, sanctuaries, lost cities, and pilgrimage routes held sacred around the world.” (Book Passage 1/2000) “For each site, Brad Olsen provides historical background, a description of the site and its special features, and directions for getting there.” (Theology Digest Summer, 2000) “(Readers) will thrill to the wonderful history and the vibrations of the world’s sacred healing places.” (East & West 2/2000) “Sites that emanate the energy of sacred spots.” (The Sunday Times 1/2000) “Sacred sites (to) the ruins, sanctuaries, mountains, lost cities, temples, and pilgrimage routes of ancient civilizations.” (San Francisco Chronicle 1/2000) “Many sacred places are now bustling tourist and pilgrimage desti- nations. But no crowd or souvenir shop can stand in the way of a traveler with great intentions and zero expectations.” (Spirituality & Health Summer, 2000) “Unleash your imagination by going on a mystical journey. Brad Olsen gives his take on some of the most amazing and unexplained spots on the globe — including the underwater ruins of Bimini, which seems to point the way to the Lost City of Atlantis. You can choose to take an armchair pilgrimage (the book is a fascinating read) or follow his tips on how to travel to these powerful sites yourself.” (Mode 7/2000) “Should you be inspired to make a pilgrimage of your own, you might want to pick up a copy of Brad Olsen’s guide to the world’s sacred places. Olsen’s marvelous drawings and mysterious maps enhance a package that is as bizarre as it is wonderfully acces- sible.
    [Show full text]
  • British Archaeological Reports
    British Archaeological Reports Gordon House, 276 Banbury Road, Oxford OX2 7ED, England Tel +44 (0) 1865 311914 Fax +44 (0) 1865 512231 [email protected] www.archaeopress.com TITLES IN PRINT NOVEMBER 2013 BAR INTERNATIONAL SERIES The BAR series of archaeological monographs were started in 1974 by Anthony Hands and David Walker. From 1991, the publishers have been Tempus Reparatum, Archaeopress and John and Erica Hedges. From 2010 they are published exclusively by Archaeopress. Descriptions of the Archaeopress titles are to be found on www.archaeopress.com Publication proposals to [email protected] Sign up to our ALERTS SERVICE Find us on Facebook www.facebook.com/Archaeopress. and Twitter www.twitter.com/archaeopress BAR –S99 2001 (1981) The Defence of Byzantine Africa from Justinian to the Arab Conquest An account of the military history and archaeology of the African provinces in the sixth and seventh centuries by Denys Pringle. ISBN 0860541193. £18.00. AVAILABLE ONLY AS PDF DOWNLOAD £18.00 inc VAT. BAR –S545, 1989 Ecology, Settlement and History in the Osmore Drainage, Peru edited by Don S. Rice, Charles Stanish and Philip R. Scarr. ISBN 0 86054 692 6. £42.00. BAR –S546, 1989 Formal Variation in Australian Spear and Spearthrower Technology by B. J. Cundy. ISBN 0 86054 693 4. £13.00. BAR –S547, 1989 The Early Roman Frontier in the Upper Rhine Area Assimilation and Acculturation on a Roman Frontier by Marcia L. Okun. ISBN 0 86054 694 2. £25.00. BAR –S548, 1989 Computer Applications and Quantitative Methods in Archaeology 1989 edited by Sebastian Rahtz and Julian Richards.
    [Show full text]