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HIV MEDICINE Published on Behalf of the British HIV Association and the European AIDS Clinical Society HIV MEDICINE Published on behalf of the British HIV Association and the European AIDS Clinical Society Editors Brian Gazzard, UK HINARI: Access to this journal is available free online within institutions Jens Lundgren, Denmark in the developing world through the HINARI initiative with the WHO. For information, visit www.who.int/hinari/en/ Editorial Board Wiley is a founding member of the UN-backed HINARI, AGORA, and OARE José Gatell, Spain initiatives. They are now collectively known as Research4Life, making online scientific content available free or at nominal cost to researchers in developing Margaret Johnson, UK countries. Please visit Wiley’s Content Access – Corporate Citizenship site: Jürgen Rockstroh, Germany http://www.wiley.com/WileyCDA/Section/id-390082.html Georg Behrens, Germany Ian Williams, UK Publisher and Business Correspondence Editorial Panel HIV Medicine is published by John Wiley & Sons Ltd: 9600 Francisco Antunes, Portugal Jeff Lazarus, Denmark Garsington Road, Oxford OX4 2DQ, UK. Tel: +44 (0)1865 776868, Fax: Jose Arribas, Spain Adriano Lazzarin, Italy +44 (0)1865 714591. Blackwell Publishing was acquired by John Wiley & Jason Baker, USA Paddy Mallon, Dublin Sons in February 2007. Wiley’s Corporate Citizenship initiative seeks to address the environmental, Georg Behrens, Germany Esteban Martinez, Spain social, economic, and ethical challenges faced in our business and which Jordi Blanch, Spain Frank Miedema, Netherlands are important to our diverse stakeholder groups. Since launching the Stéphane Blanche, France José M Miró, Spain initiative, we have focused on sharing our content with those in need, Ray Brettle, UK Amanda Mocroft, London enhancing community philanthropy, reducing our carbon impact, creating Françoise Brun-Vézinet, France Jean-Michel Molina, France global guidelines and best practices for paper use, establishing a vendor Alexandra Calmy, Switzerland Fiona Mulcahy, Ireland code of ethics, and engaging our colleagues and other stakeholders in our Richard Chaisson, USA Robert Murphy, USA efforts. Follow our progress at www.wiley.com/go/citizenship. Duncan Churchill, UK Mark Nelson, UK Journal Customer Services: For ordering information, claims and Bonaventura Clotet, Spain George Panos, Greece any enquiry concerning your journal subscription please go to Nathan Clumeck, Belgium Deenan Pillay, UK www.wileycustomerhelp.com/ask or contact your nearest office. Dominique Costagliola, France Daniel Podzamczer, Spain Americas: E-mail: [email protected]; Tel: +1 781 388 8598 or Antonella d’Arminio Monforte, Italy Bruce Polsky, USA +1 800 835 6770 (Toll free in the USA and Canada). Andrea de Luca, Rome Frank Post, UK Europe, Middle East and Africa: E-mail: [email protected]. Joseph Eron, USA Anton Pozniak, UK Asia Pacific: E-mail: [email protected]; Tel: +65 6511 8000. Hans-Jacob Furrer, Switzerland François Raffi, France Japan: For Japanese speaking support, Email: [email protected]. Visit our Online Customer Get-Help available in 7 languages at Christoph Fux, Switzerland Peter Reiss, Netherlands www.wileycustomerhelp.com/ask. Carlo Giaquinto, J. Richard Smith, Italy UK Advertising: Sarah Young, HIV Medicine advertising Andrew Grulich, Australia Vincent Soriano, Spain (email: [email protected]) Scott Hammer, USA Ann Sullivan, UK Commercial reprints: Claire Porter Graham Hart, UK Stefano Vella, Italy (email: [email protected]) Andrzej Horban, Poland Ed Wilkins, UK Christine Katlama, France Robin Wood, Cape Town Peter Kelleher, UK Copyright and Copying HIV Medicine © 2017 British HIV Association. All rights reserved. No Editorial Office part of this publication may be reproduced, stored or transmitted in Editorial Director: Ann O'Mahony any form or by any means without the prior permission in writing from Wiley Blackwell the copyright holder. Authorization to copy items for internal and personal use is granted by the copyright holder for libraries and other 9600 Garsington Road users registered with their local Reproduction Rights Organisation (RRO), Oxford, OX4 2DQ, UK e.g. Copyright Clearance Center (CCC), 222 Rosewood Drive, Danvers, Fax: +44 1865 714 591 MA 01923, USA (www.copyright.com), provided the appropriate fee is E-mail: [email protected] paid directly to the RRO. This consent does not extend to other kinds of copying such as copying for general distribution for advertising or Production Editor promotional purposes, for creating new collective works or for resale. John Marlou De Guzman (e-mail: [email protected]) Special requests should be addressed to: [email protected] OnlineOpen HIV Medicine accepts articles for Open Access publication. Please visit Aims and Scope http://olabout.wiley.com/WileyCDA/Section/id-828081.html for further HIV Medicine aims to provide an alternative outlet for publication of information about OnlineOpen. international research papers in the field of HIV Medicine, embracing clinical, pharmacological, epidemiological, ethical, preclinical and Disclaimer in vitro studies. In addition, the journal will commission reviews and other feature articles. It will focus on evidence-based medicine as the The Publisher, the British HIV Association, the European AIDS Clinical mainstay of successful management of HIV and AIDS. Society and the Editors cannot be held responsible for errors or any consequences arising from the use of information contained in this Information for Subscribers journal; the views and opinions expressed do not necessarily reflect those HIV Medicine is published in 10 issues per year. Institutional subscription of the Publisher, the British HIV Association, the European AIDS Clinical prices for 2016 are: Print & Online: US$2428 (US), US$2830 (Rest of Society and the Editors, neither does the publication of advertisements World), €1670 (Europe), £1317 (UK). Prices are exclusive of tax. Asia- constitute any endorsement by the Publisher, the British HIV Association, Pacific GST, Canadian GST/HST and European VAT will be applied at the the European AIDS Clinical Society and Editors of the products advertised. appropriate rates. For more information on current tax rates, please go to ISSN 1464-2662 (Print) www.wileyonlinelibrary.com/tax-vat. The price includes online access to ISSN 1468-1293 (Online) the current and all online back files to January 1st 2012, where available. For submission instructions, subscription and all other For other pricing options, including access information and terms and information visit: www.hivmedicinejournal.com conditions, please visit www.wileyonlinelibrary.com/access. Note to NIH Grantees Delivery Terms and Legal Title Pursuant to NIH mandate, Wiley Blackwell will post the accepted version Where the subscription price includes print issues and delivery is to of contributions authored by NIH grant-holders to PubMed Central upon the recipient’s address, delivery terms are Delivered at Place (DAP); acceptance. This accepted version will be made publicly available 12 the recipient is responsible for paying any import duty or taxes. Title months after publication. For further information, see www.wiley.com/go/ to all issues transfers FOB our shipping point, freight prepaid. We will nihmandate. endeavour to fulfil claims for missing or damaged copies within six months of publication, within our reasonable discretion and subject to HIV MEDICINE (1464-2662) is published monthly except June and availability. December. US mailing agent: Mercury Media Processing, LLC 1850 Back issues: Single issues from current and recent volumes are available at Elizabeth Avenue, Suite #C, Rahway, NJ 07065 USA. Periodical postage the current single issue price from [email protected]. Earlier issues paid at Rahway, NJ. POSTMASTER: Send all address changes to HIV may be obtained from Periodicals Service Company, 351 Fairview Avenue MEDICINE, John Wiley & Sons Inc., C/O The Sheridan Press, PO Box 465, – Ste 300, Hudson, NY 12534, USA. Hanover, PA 17331 USA. Tel: +1 518 822-9300, Fax: +1 518 822-9305, Typeset by Scientific Publishing Services (P) Ltd, Email: [email protected] and printed in Singapore by Markono Print Media Pte Ltd. HIV MEDICINE Volume 18, Supplement 1, April 2017 Abstracts of the 23rd Annual Conference of the British HIV Association (BHIVA) Liverpool, UK 4–7 April 2017 Contents Oral Abstracts O1–O6 Antiretroviral Therapy 3 O7–O15 Testing and Early Infection 5 O16–O24 Toxicities and Comorbidities 8 O25–O30 Living with HIV 11 Poster Abstracts P1–P23 Antiretrovirals: Efficacy, Interactions and Pharmacokinetics 14 P24–P27 Basic Science: Immunology, Virology and Pathogenesis 22 P28–P35 Behaviour, Transmission and Prevention 23 P36–P48 Children and Pregnancy 26 P49–P106 Comorbidities, Co-infections and HIV/ART Complications 30 P107–P131 HIV Testing, Epidemiology and Surveillance 48 P132–P143 Psychosocial Issues and Quality of Life 55 P144–P169 Service Development, Education and Training 59 P170–P176 STIs, Reproductive Health, Contraception and Sexual Dysfunction 68 Disclaimer This abstract book has been produced using author-supplied copy. No responsibility is assumed for any claims, instructions, methods or drug dosages contained in the abstracts; it is recommended that these are verified independently. EDITORS EDITORIAL BOARD Brian Gazzard, UK José Gatell, Spain Jens Lundgren, Denmark Margaret Johnson, UK Jürgen Rockstroh, Germany Schlomo Staszewski, Germany Ian Williams, UK Oral Abstracts Methods: A single (SD) and multiple-dose (MD) randomized, double-blind, placebo-controlled (6 active 2 placebo/cohort) of
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